isradipine and 4-desmethoxyverapamil

isradipine has been researched along with 4-desmethoxyverapamil in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's12 (50.00)18.2507
2000's1 (4.17)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glossmann, H; Knaus, HG; Staudinger, R1
Rampe, D; Triggle, DJ; Zheng, W1
Beaufort, P; Chatelain, P; Clinet, M; Laruel, R; Meysmans, L; Nokin, P1
Dacquet, C; Mironneau, C; Mironneau, J; Rakotoarisoa, L; Sayet, I1
Glossmann, H; Knaus, HG; Romanin, C; Scheffauer, F; Schindler, HG1
Mironneau, C; Mironneau, J; Rakotoarisoa, L; Sayet, I1
Hosey, MM; McMahon, KK; Ptasienski, J1
Glossmann, H; Goll, A; Moosburger, K; Striessnig, J1
Barhanin, J; Borsotto, M; Fosset, M; Galizzi, JP; Lazdunski, M; Renaud, JF; Romey, G; Schmid, A1
Hofmann, F; Nastainczyk, W; Sieber, M; Wernet, W; Zubor, V1
Dillon, JS; Gu, XH; Nayler, WG1
Dillon, JS; Gu, XH; Liu, JJ; Nayler, WG1
Hudecová, S; Krizanová, O; Orlický, J; Zachar, J1
Garcia, L; Lazdunski, M; Rieger, F; Romey, G1
Barhanin, J; Henning, R; Lazdunski, M; Lerch, U; Oekonomopulos, R; Qar, J; Romey, G; Urbach, H1
Barhanin, J; Borsotto, M; Fosset, M; Galizzi, JP; Lazdunski, M1
Reynolds, IJ; Snowman, AM; Snyder, SH1
Anderson, K; Meissner, G1
Lombet, A; Spedding, M1
Boksa, P; Quirion, R; Sen, AP1
Hagiwara, M; Nagao, T; Shimasue, K; Urushidani, T1
Abu Khoudoud, OR; Bikhazi, AB; Bitar, KM; el-Kasti, MM; Ibrahim, MZ; Kreydiyyeh, SI; Saleh, RS1
Adachi-Akahane, S; Hagiwara, M; Nagao, T1
El Bardai, S; Hamaide, MC; Lyoussi, B; Morel, N; Quetin-Leclercq, J; Wibo, M1

Other Studies

24 other study(ies) available for isradipine and 4-desmethoxyverapamil

ArticleYear
Positive heterotropic allosteric regulators of dihydropyridine binding increase the Ca2+ affinity of the L-type Ca2+ channel. Stereoselective reversal by the novel Ca2+ antagonist BM 20.1140.
    The Journal of biological chemistry, 1991, Jun-15, Volume: 266, Issue:17

    Topics: Alkaloids; Allosteric Regulation; Animals; Benzothiazoles; Benzylisoquinolines; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; Diltiazem; Guinea Pigs; Isomerism; Isradipine; Kinetics; Macromolecular Substances; Models, Theoretical; Muscles; Oxadiazoles; Pyridines; Pyrrolidines; Rabbits; Thiazoles; Verapamil

1991
Pharmacological, radioligand binding, and electrophysiological characteristics of FPL 64176, a novel nondihydropyridine Ca2+ channel activator, in cardiac and vascular preparations.
    Molecular pharmacology, 1991, Volume: 40, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Isradipine; Male; Myocardium; Potassium; Pyrroles; Radioligand Assay; Rats; Vasoconstriction; Verapamil

1991
SR 33557, a novel calcium entry blocker. II. Interactions with 1,4-dihydropyridine, phenylalkylamine and benzothiazepine binding sites in rat heart sarcolemmal membranes.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Indolizines; Isradipine; Male; Myocardium; Oxadiazoles; Phenethylamines; Radioligand Assay; Rats; Rats, Inbred Strains; Sarcolemma; Verapamil

1990
Interactions of spironolactone with (+)-[3H]-isradipine and (-)-[3H]-desmethoxyverapamil binding sites in vascular smooth muscle.
    British journal of pharmacology, 1990, Volume: 101, Issue:1

    Topics: Animals; Binding Sites; Calcium Channel Blockers; Cell Membrane; Horses; In Vitro Techniques; Isradipine; Ligands; Muscle, Smooth, Vascular; Portal Vein; Progesterone; Pyridines; Spironolactone; Verapamil

1990
Heparin binds with high affinity to voltage-dependent L-type Ca2+ channels. Evidence for an agonistic action.
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Calcium Channels; Carps; Cell Membrane; Cerebral Cortex; Dihydropyridines; Diltiazem; Electric Conductivity; Guinea Pigs; Heparin; Isradipine; Molecular Sequence Data; Muscles; Myocardium; Nicotinic Antagonists; Oxadiazoles; Polyelectrolytes; Polymers; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil

1990
Selective modulation by membrane potential of desmethoxyverapamil binding to calcium channels in rat portal vein.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Animals; Barium; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Isradipine; Kinetics; Membrane Potentials; Muscle, Smooth, Vascular; Portal Vein; Pyridines; Rats; Strontium; Verapamil

1990
High and low affinity states of the dihydropyridine and phenylalkylamine receptors on the cardiac calcium channel and their interconversion by divalent cations.
    Biochemical and biophysical research communications, 1985, Jun-28, Volume: 129, Issue:3

    Topics: Animals; Calcium; Cations, Divalent; Chickens; Dihydropyridines; Heart; Ion Channels; Isradipine; Magnesium; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil

1985
Purified calcium channels have three allosterically coupled drug receptors.
    FEBS letters, 1986, Mar-03, Volume: 197, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Amines; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil

1986
Dihydropyridine-sensitive Ca2+ channels: molecular properties of interaction with Ca2+ channel blockers, purification, subunit structure, and differentiation.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Bepridil; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Chick Embryo; Cholic Acids; Diltiazem; Ion Channels; Isradipine; Kinetics; Macromolecular Substances; Molecular Weight; Muscles; Myocardial Contraction; Oxadiazoles; Pyridines; Pyrrolidines; Receptors, Nicotinic; Verapamil

1986
The 165-kDa peptide of the purified skeletal muscle dihydropyridine receptor contains the known regulatory sites of the calcium channel.
    European journal of biochemistry, 1987, Aug-17, Volume: 167, Issue:1

    Topics: Affinity Labels; Animals; Azides; Calcium; Calcium Channels; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Molecular Weight; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Verapamil

1987
Effect of age and of hypertrophy on cardiac Ca2+ antagonist binding sites.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:2

    Topics: Aging; Animals; Blood Pressure; Body Weight; Calcium Channels; Cardiomegaly; Cell Membrane; Dihydropyridines; Indicators and Reagents; Isradipine; Male; Myocardium; Oxadiazoles; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Nicotinic; Time Factors; Verapamil

1989
The failure of endothelin to displace bound, radioactively-labelled, calcium antagonists (PN 200/110, D888 and diltiazem).
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Diltiazem; Endothelins; Female; In Vitro Techniques; Isradipine; Oxadiazoles; Peptides; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Verapamil

1989
Is Ca2+ antagonists binding protein from cytosolic fraction the precursor of alpha 1-subunit of Ca2+ channel?
    General physiology and biophysics, 1989, Volume: 8, Issue:2

    Topics: Affinity Labels; Animals; Antibodies; Azides; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cytoplasm; Dihydropyridines; In Vitro Techniques; Isradipine; Muscles; Oxadiazoles; Protein Precursors; Rabbits; Radioligand Assay; Receptors, Nicotinic; Ultraviolet Rays; Verapamil

1989
Targets for calcium channel blockers in mammalian skeletal muscle and their respective functions in excitation-contraction coupling.
    Biochemical and biophysical research communications, 1988, Nov-15, Volume: 156, Issue:3

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Evoked Potentials; Isradipine; Mice; Muscle Contraction; Oxadiazoles; Piperidines; Thiazines; Verapamil

1988
A novel high affinity class of Ca2+ channel blockers.
    Molecular pharmacology, 1988, Volume: 33, Issue:4

    Topics: Animals; Bepridil; Binding Sites; Calcium Channel Blockers; Cell Line; Dihydropyridines; Fluspirilene; Isradipine; Kinetics; Muscles; Oxadiazoles; Piperidines; Pyrrolidines; Rabbits; Rats; Structure-Activity Relationship; Thiazines; Verapamil

1988
Characterization and photoaffinity labeling of receptor sites for the Ca2+ channel inhibitors d-cis-diltiazem, (+/-)-bepridil, desmethoxyverapamil, and (+)-PN 200-110 in skeletal muscle transverse tubule membranes.
    The Journal of biological chemistry, 1986, Jan-25, Volume: 261, Issue:3

    Topics: Affinity Labels; Animals; Autoradiography; Benzazepines; Bepridil; Binding, Competitive; Calcium Channels; Diltiazem; Isradipine; Kinetics; Muscles; Oxadiazoles; Photochemistry; Pyrrolidines; Rabbits; Receptors, Nicotinic; Verapamil

1986
(-)-[3H] desmethoxyverapamil labels multiple calcium channel modulator receptors in brain and skeletal muscle membranes: differentiation by temperature and dihydropyridines.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Animals; Brain Chemistry; Calcium; Calcium Channels; Cell Membrane; Dihydropyridines; Female; Isradipine; Kinetics; Male; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Stereoisomerism; Temperature; Tritium; Verapamil

1986
T-tubule depolarization-induced SR Ca2+ release is controlled by dihydropyridine receptor- and Ca(2+)-dependent mechanisms in cell homogenates from rabbit skeletal muscle.
    The Journal of general physiology, 1995, Volume: 105, Issue:3

    Topics: Animals; Calcium; Calcium Channels, L-Type; Egtazic Acid; Electrophysiology; Isradipine; Microtubules; Muscle Proteins; Muscle, Skeletal; Nifedipine; Rabbits; Sarcoplasmic Reticulum; Verapamil

1995
Differential effects of non-peptidic tachykinin receptor antagonists on Ca2+ channels.
    European journal of pharmacology, 1994, Mar-15, Volume: 267, Issue:1

    Topics: Animals; Calcium Channels; Dihydropyridines; In Vitro Techniques; Isradipine; Muscles; Rats; Receptors, Tachykinin; Verapamil

1994
Brain calcium channel related dihydropyridine and phenylalkylamine binding sites in Alzheimer's, Parkinson's and Huntington's diseases.
    Brain research, 1993, May-21, Volume: 611, Issue:2

    Topics: Aged; Alzheimer Disease; Autopsy; Binding Sites; Brain; Calcium; Calcium Channels; Dihydropyridines; Female; Humans; Huntington Disease; Isradipine; Male; Middle Aged; Organ Specificity; Parkinson Disease; Reference Values; Verapamil

1993
Effects of anandamide and arachidonic acid on specific binding of (+) -PN200-110, diltiazem and (-) -desmethoxyverapamil to L-type Ca2+ channel.
    European journal of pharmacology, 1996, Feb-05, Volume: 296, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium Channel Blockers; Calcium Channels; Diltiazem; Endocannabinoids; Isradipine; Male; Polyunsaturated Alkamides; Rabbits; Verapamil

1996
Binding and distribution of three prototype calcium channel blockers in perfused rat liver.
    Molecular and cellular biochemistry, 1997, Volume: 169, Issue:1-2

    Topics: Animals; Azides; Calcium Channel Blockers; Calcium Channels; Carbon Radioisotopes; Dihydropyridines; Inulin; Isradipine; Liver; Models, Biological; Perfusion; Rats; Rats, Sprague-Dawley; Time Factors; Tritium; Urea; Verapamil

1997
High-affinity binding of DTZ323, a novel derivative of diltiazem, to rabbit skeletal muscle L-type Ca++ channels.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Diltiazem; Isradipine; Male; Muscle, Skeletal; Rabbits; Verapamil

1997
Marrubenol interacts with the phenylalkylamine binding site of the L-type calcium channel.
    European journal of pharmacology, 2004, May-25, Volume: 492, Issue:2-3

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diterpenes; Furans; Ileum; In Vitro Techniques; Isradipine; Male; Membranes; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Radioligand Assay; Rats; Rats, Wistar; Vasodilator Agents; Verapamil

2004