Compounds > isradipine

isradipine and 1,4-dihydropyridine

isradipine has been researched along with 1,4-dihydropyridine in 82 studies

Research

Studies (82)

TimeframeStudies, this research(%)All Research%
pre-199018 (21.95)18.7374
1990's50 (60.98)18.2507
2000's14 (17.07)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christen, MO; Feron, O; Godfraind, T; Wibo, M1
Fekete, Z; Liu, J; Slomiany, A; Slomiany, BL; Yao, P1
Bick, IR; Felix, JP; Garcia, ML; Kaczorowski, GJ; King, VF; Shevell, JL; Slaughter, RS1
Fekete, Z; Liu, J; Murty, VL; Slomiany, A; Slomiany, BL1
Goldmann, S; Stoltefuss, J; Triggle, DJ; Zheng, W1
Latifpour, J; Weiss, RM; Yoshida, M1
Bladen, C; Dunn, SM2
Bravo, G; Godfraind, T; Wibo, M1
Mironneau, C; Mironneau, J; Rakotoarisoa, L; Sayet, I1
Lory, P; Schultz, D; Schwartz, A; Varadi, G; Varadi, M1
Drímal, J1
Rudin, M; Sauter, A1
Bezáková, G; Krizanová, O; Lehotský, J; Mézesová, V1
Fujimoto, M; Mihara, S1
Ebata, H; Mitsuhashi, T; Natsume, T; Yaginuma, T1
Ebata, H; Johnson, JD; Mills, JS; Nemcek, K1
Glossmann, H; Knaus, HG; Romanin, C; Scheffauer, F; Schindler, HG1
Ahlijanian, MK; Catterall, WA; Westenbroek, RE1
Hosey, MM; McMahon, KK; Ptasienski, J1
Glossmann, H; Goll, A; Moosburger, K; Striessnig, J1
Brown, AM; Brush, K; Hamilton, SL; Schwartz, A; Yatani, A1
Froehner, SC; Morton, ME1
Askanas, V; Desnuelle, C; Engel, WK1
Beam, KG; Knudson, CM1
Massieu, L; Tapia, R1
Dunn, SM1
Castillo, CJ; Fonteríz, RI; García, AG; López, MG; Rosenheck, K1
Alvarez, RM; Brush, KL; Fill, M; Hamilton, SL; Hawkes, MJ; Schilling, WP; Stefani, E1
Brown, AM; Caffrey, JM; Rampe, D; Schneider, MD1
Bode-Greuel, KM; Singer, W1
Quirion, R1
Gerard, P; Huchet, AM; Huguet, F; Narcisse, G1
Barhanin, J; Henning, R; Lazdunski, M; Lerch, U; Oekonomopulos, R; Qar, J; Romey, G; Urbach, H1
Schilling, WP1
Barhanin, J; Borsotto, M; Fosset, M; Lazdunski, M1
Reynolds, IJ; Snowman, AM; Snyder, SH1
Liu, J; Rutledge, A; Triggle, DJ1
Sze, PY; Yu, BH1
Canda, A; Sze, PY; Yu, BH1
Beam, KG; Dirksen, RT1
Rao, MR; Xu, Y1
Hayashi, T; Kato, H; Koshino, Y; Kutsumi, Y; Miyabo, S; Nakai, T; Oida, K1
Bourachot, ML; Crouzel, C; Fuseau, C; Syrota, A; Valette, H1
Bangalore, R; Liu, J; Rutledge, A; Triggle, DJ1
Do Carmo, LG; Jurkiewicz, A; Jurkiewicz, NH; Lafayette, SS; Martini, LC; Nunes, SH; Wanderley, AG1
Ganunis, TF; Helfaer, MA; Hoehner, PJ; Kirsch, JR; Murphy, MT; Traystman, RJ1
Gayman, KJ; Lachnit, WG; Pessah, IN; Phillips, M1
Cagnotto, A; Gaviraghi, G; Mennini, T; Micheli, D; Ratti, E; Taddei, C; Trist, D; Uslenghi, A1
Lombet, A; Spedding, M1
Fekete, Z; Liu, J; Slomiany, A; Slomiany, BL1
Glossmann, H; Grabner, M; Hering, S; Striessnig, J; Wang, Z1
Catterall, WA; Peterson, BZ; Tanada, TN1
Jacobson, KA; Jiang, JL; Melman, N; Olah, ME; Stiles, GL; van Rhee, AM1
Borea, PA; Cerbai, E; Gessi, S; Guerra, L; Mugelli, A1
Hamman, BN; Thomas, MJ; Tibbits, GF1
Birnbaumer, L; Suh-Kim, H; Wei, X1
Guerrier, P; Krantic, S; Tomkowiak, M1
Blanck, TJ; Curtis, WE; Gardner, TJ; Quigg, M; Yasukochi, S1
Campbell, KP; De Waard, M; Felix, R; Gurnett, CA1
Hofmann, F; Ito, H; Klugbauer, N1
Kanaya, N; Kawana, S; Kimura, H; Matsumoto, M; Miyamoto, A; Namiki, A; Ohshika, H; Tsuchida, H1
Frick, GP; Gaur, S; Goodman, HM; Morton, ME1
Grabner, M; Hering, S; Kraus, RL; Ostler, D; Striessnig, J1
Hofmann, F; Hu, M; Klugbauer, N; Lacinová, L1
Grant, KA; Green, KL1
Ait-Daoud, N; Bordnick, PS; Johnson, BA; Roache, JD1
Gonon, A; Nordlander, M; Rydén, L; Segawa, D; Sjöquist, PO; Wang, QD1
Ait-Daoud, N; Johnson, BA; Wells, LT1
Hofmann, F; Klugbauer, N; Lacinová, L1
Deguchi, Y; Kimura, R; Uchida, S; Yamada, S; Yamamoto, M1
Carroll, EM; Collins, PL; Gianopoulos, JG1
Glossmann, H; Mitterdorfer, J; Striessnig, J; Wappl, E1
Bidet, M; Martial, S; Martin, D; Melendez, E; Namorado, MD; Poujeol, C; Poujeol, P; Reyes, JL; Sanchez, E; Tauc, M; Valencia, L1
Dolphin, AC; Nürnberg, B; Plant, TD; Scholze, A1
Ait-Daoud, N; Devous, MD; Johnson, BA; Ruiz, P1
Grabner, M; Heinzle, T; Hoda, JC; Koschak, A; Reimer, D; Striessnig, J; Walter, D1
Adachi-Akahane, S; Ichijo, H; Nagao, T; Yamaguchi, S; Yoshioka, K; Zhorov, BS1
Hofmann, F; Lee, M; Wegener, JW1
El Bardai, S; Hamaide, MC; Lyoussi, B; Morel, N; Quetin-Leclercq, J; Wibo, M1
Fujimura, S; Hattori, T; Hirai, K; Wang, P1
Hoda, JC; Huber, IG; Sinnegger-Brauns, MJ; Striessnig, J; Walter-Bastl, D; Wappl-Kornherr, E1

Reviews

2 review(s) available for isradipine and 1,4-dihydropyridine

ArticleYear
Calcium currents in embryonic and neonatal mammalian skeletal muscle.
    The Journal of general physiology, 1988, Volume: 91, Issue:6

    Topics: Animals; Animals, Newborn; Barium; Calcium; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Electrophysiology; Embryo, Mammalian; Embryo, Nonmammalian; Ion Channels; Isradipine; Muscles; Oxadiazoles; Stereoisomerism

1988
Treatment advances for cocaine-induced ischemic stroke: focus on dihydropyridine-class calcium channel antagonists.
    The American journal of psychiatry, 2001, Volume: 158, Issue:8

    Topics: Brain Ischemia; Calcium Channel Blockers; Cocaine-Related Disorders; Dihydropyridines; Humans; Isradipine; Stroke; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Vasospasm, Intracranial

2001

Trials

2 trial(s) available for isradipine and 1,4-dihydropyridine

ArticleYear
Isradipine, a dihydropyridine-class calcium channel antagonist, attenuates some of d-methamphetamine's positive subjective effects: a preliminary study.
    Psychopharmacology, 1999, Volume: 144, Issue:3

    Topics: Adrenergic Agents; Adult; Affect; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Double-Blind Method; Drug Antagonism; Female; Humans; Isradipine; Male; Methamphetamine; Middle Aged; Reinforcement, Psychology; Reward; Substance-Related Disorders

1999
Effects of isradipine, a dihydropyridine-class calcium channel antagonist, on D-methamphetamine-induced cognitive and physiological changes in humans.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 22, Issue:5

    Topics: Adult; Amphetamine-Related Disorders; Calcium Channel Blockers; Cardiovascular Physiological Phenomena; Cognition; Cross-Over Studies; Dihydropyridines; Double-Blind Method; Female; Humans; Isradipine; Male; Methamphetamine; Middle Aged; Nootropic Agents

2000

Other Studies

78 other study(ies) available for isradipine and 1,4-dihydropyridine

ArticleYear
Interaction of pinaverium (a quaternary ammonium compound) with 1,4-dihydropyridine binding sites in rat ileum smooth muscle.
    British journal of pharmacology, 1992, Volume: 105, Issue:2

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Dihydropyridines; Diltiazem; Ileum; In Vitro Techniques; Isradipine; Kinetics; Morpholines; Muscle, Smooth; Parasympatholytics; Rats; Receptors, Nicotinic; Saponins

1992
Modulation of dihydropyridine-sensitive gastric mucosal calcium channels by GM1-ganglioside.
    The International journal of biochemistry, 1992, Volume: 24, Issue:8

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Cell Membrane; Dihydropyridines; G(M1) Ganglioside; Gastric Mucosa; Isradipine; Lanthanum; Liposomes; Male; Osmolar Concentration; Phosphatidylcholines; Rats; Rats, Inbred Strains

1992
Bis(benzylisoquinoline) analogs of tetrandrine block L-type calcium channels: evidence for interaction at the diltiazem-binding site.
    Biochemistry, 1992, Dec-01, Volume: 31, Issue:47

    Topics: Alkaloids; Animals; Benzylisoquinolines; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Fluspirilene; Gallopamil; Isoquinolines; Isradipine; Kinetics; Molecular Conformation; Molecular Structure; Myocardium; Sarcolemma; Swine

1992
Activation of dihydropyridine-sensitive parotid salivary gland calcium channels by epidermal growth factor.
    Archives of oral biology, 1992, Volume: 37, Issue:11

    Topics: Animals; Calcium; Calcium Channels; Calcium Radioisotopes; Cell Membrane; Dihydropyridines; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Isradipine; Lanthanum; Liposomes; Male; Parotid Gland; Phosphorylation; Rats; Rats, Sprague-Dawley; Tyrosine

1992
Pharmacologic and radioligand binding studies of 1,4-dihydropyridines in rat cardiac and vascular preparations: stereoselectivity and voltage dependence of antagonist and activator interactions.
    Molecular pharmacology, 1992, Volume: 41, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Binding, Competitive; Calcium Channel Blockers; Dihydropyridines; Drug Antagonism; Heart; In Vitro Techniques; Isradipine; Male; Muscle Contraction; Nifedipine; Radioligand Assay; Rats

1992
Evidence for the presence of regional differences in the calcium antagonist receptors in lower urinary tract smooth muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:6

    Topics: Animals; Binding Sites; Calcium Channel Blockers; Carbachol; Dihydropyridines; Drug Interactions; Female; Isradipine; Muscle Contraction; Muscle, Smooth; Nifedipine; Rabbits; Urinary Tract

1992
Low-affinity binding sites for 1,4-dihydropyridines in skeletal muscle transverse tubule membranes revealed by changes in the fluorescence of felodipine.
    Biochemistry, 1992, Apr-28, Volume: 31, Issue:16

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cations; Cell Membrane; Dihydropyridines; Felodipine; Fluorescent Dyes; Isradipine; Kinetics; Muscles; Rabbits; Spectrometry, Fluorescence

1992
Kinetics of binding of dihydropyridine calcium channel ligands to skeletal muscle membranes: evidence for low-affinity sites and for the involvement of G proteins.
    Biochemistry, 1991, Jun-11, Volume: 30, Issue:23

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Isradipine; Kinetics; Ligands; Membrane Proteins; Microsomes; Muscles; Nitrendipine; Oxadiazoles; Rabbits; Receptors, Nicotinic; Stereoisomerism; Thionucleotides

1991
Postnatal maturation of excitation-contraction coupling in rat ventricle in relation to the subcellular localization and surface density of 1,4-dihydropyridine and ryanodine receptors.
    Circulation research, 1991, Volume: 68, Issue:3

    Topics: Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Dihydropyridines; Heart Ventricles; Isradipine; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cholinergic; Ryanodine; Ryanodine Receptor Calcium Release Channel; Subcellular Fractions; Ventricular Function

1991
Modulation of [3H]dihydropyridine binding by activation of protein kinase C in vascular smooth muscle.
    European journal of pharmacology, 1991, Nov-13, Volume: 208, Issue:3

    Topics: Aluminum; Animals; Binding Sites; Calcium Channels; Dihydropyridines; Enzyme Activation; Fluorine; Horses; In Vitro Techniques; Isradipine; Membrane Potentials; Membranes; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phorbol Esters; Phosphorylation; Portal Vein; Potassium Chloride; Protein Kinase C; Tritium

1991
Acceleration of activation and inactivation by the beta subunit of the skeletal muscle calcium channel.
    Nature, 1991, Jul-11, Volume: 352, Issue:6331

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Binding Sites; Calcium Channels; Cell Line; Cell Membrane; Dihydropyridines; DNA; Electric Conductivity; Gene Expression; Ion Channel Gating; Isradipine; Kinetics; L Cells; Macromolecular Substances; Muscles; Oxadiazoles; Rabbits; Receptors, Nicotinic; Transfection

1991
The beta-adrenergic receptor-regulated 1,4-dihydropyridine calcium channel receptor sites in coronary artery smooth muscle.
    Physiological research, 1991, Volume: 40, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channels; Cell Membrane; Cyclic AMP; Dihydropyridines; Dogs; Guanosine Triphosphate; Isoproterenol; Isradipine; Male; Microsomes; Muscle, Smooth, Vascular; Receptors, Adrenergic, beta

1991
Prevention of stroke and brain damage with calcium antagonists in animals.
    American journal of hypertension, 1991, Volume: 4, Issue:2 Pt 2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain Damage, Chronic; Calcium Channel Blockers; Cerebrovascular Disorders; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Isradipine; Male; Prognosis; Pyridines; Rats; Rats, Inbred SHR

1991
Denervation induced changes in level of Ca-antagonists binding cytosolic protein from white skeletal muscle.
    General physiology and biophysics, 1991, Volume: 10, Issue:1

    Topics: Animals; Calcium Channel Blockers; Cytosol; Denervation; Dihydropyridines; Electrophoresis, Polyacrylamide Gel; Isradipine; Microsomes; Muscles; Oxadiazoles; Rabbits; Receptors, Cholinergic

1991
Effect of S-312, a new calcium channel blocker, on the 1,4-dihydropyridine binding sites in porcine basilar blood vessels and rat aortic smooth muscle cells.
    Japanese journal of pharmacology, 1991, Volume: 56, Issue:3

    Topics: Animals; Aorta; Basilar Artery; Binding Sites; Calcium; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Isradipine; Muscle, Smooth, Vascular; Nicardipine; Nitrendipine; Oxadiazoles; Rats; Swine

1991
Reduced calcium sensitivity of dihydropyridine binding to calcium channels in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:2

    Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Isradipine; Male; Microsomes; Muscles; Myocardium; Oxadiazoles; Rats; Rats, Inbred SHR

1991
Calcium binding to extracellular sites of skeletal muscle calcium channels regulates dihydropyridine binding.
    The Journal of biological chemistry, 1990, Jan-05, Volume: 265, Issue:1

    Topics: Animals; Binding Sites; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels; Cations, Divalent; Cell Membrane; Dihydropyridines; Edetic Acid; Egtazic Acid; Isradipine; Magnesium; Microsomes; Muscles; Myocardium; Oxadiazoles; Rabbits; Sarcolemma

1990
Heparin binds with high affinity to voltage-dependent L-type Ca2+ channels. Evidence for an agonistic action.
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Calcium Channels; Carps; Cell Membrane; Cerebral Cortex; Dihydropyridines; Diltiazem; Electric Conductivity; Guinea Pigs; Heparin; Isradipine; Molecular Sequence Data; Muscles; Myocardium; Nicotinic Antagonists; Oxadiazoles; Polyelectrolytes; Polymers; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil

1990
Clustering of L-type Ca2+ channels at the base of major dendrites in hippocampal pyramidal neurons.
    Nature, 1990, Sep-20, Volume: 347, Issue:6290

    Topics: Animals; Antibodies, Monoclonal; Calcium Channels; Dendrites; Dihydropyridines; Hippocampus; Immunoenzyme Techniques; Immunosorbent Techniques; Isradipine; Neurons; omega-Conotoxins; Oxadiazoles; Peptides, Cyclic; Rats; Rats, Inbred Strains; Synaptic Membranes

1990
High and low affinity states of the dihydropyridine and phenylalkylamine receptors on the cardiac calcium channel and their interconversion by divalent cations.
    Biochemical and biophysical research communications, 1985, Jun-28, Volume: 129, Issue:3

    Topics: Animals; Calcium; Cations, Divalent; Chickens; Dihydropyridines; Heart; Ion Channels; Isradipine; Magnesium; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil

1985
Purified calcium channels have three allosterically coupled drug receptors.
    FEBS letters, 1986, Mar-03, Volume: 197, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Amines; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil

1986
A comparison between the binding and electrophysiological effects of dihydropyridines on cardiac membranes.
    Molecular pharmacology, 1987, Volume: 31, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Heart; Ion Channels; Isradipine; Kinetics; Membrane Potentials; Membranes; Myocardium; Nicotinic Acids; Nimodipine; Nitrendipine; Oxadiazoles; Pyridines; Stereoisomerism; Structure-Activity Relationship

1987
Monoclonal antibody identifies a 200-kDa subunit of the dihydropyridine-sensitive calcium channel.
    The Journal of biological chemistry, 1987, Sep-05, Volume: 262, Issue:25

    Topics: Animals; Antibodies, Monoclonal; Calcium; Dihydropyridines; Electrophoresis, Polyacrylamide Gel; Ion Channels; Isradipine; Macromolecular Substances; Molecular Weight; Muscles; Oxadiazoles; Pyridines; Rabbits

1987
Dihydropyridine-sensitive Ca2+ channel in aneurally cultured human muscles. Relationship between high-affinity binding site and inhibition of calcium uptake.
    FEBS letters, 1988, Mar-28, Volume: 230, Issue:1-2

    Topics: Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cells, Cultured; Dihydropyridines; Electrophysiology; Humans; Ion Channels; Isradipine; Muscles; Nitrendipine; Oxadiazoles; Potassium

1988
Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes.
    Journal of neurochemistry, 1988, Volume: 51, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aminopyridines; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; gamma-Aminobutyric Acid; Ion Channels; Isradipine; Lanthanum; Male; Mice; Neurotransmitter Agents; Nifedipine; Nitrendipine; Oxadiazoles; Potassium; Receptors, Nicotinic; Ruthenium Red; Synaptosomes

1988
Multiple calcium channels in synaptosomes: voltage dependence of 1,4-dihydropyridine binding and effects on function.
    Biochemistry, 1988, Jul-12, Volume: 27, Issue:14

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Male; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Synaptosomes; Verapamil

1988
(+)-PN200-110 and ouabain binding sites in purified bovine adrenomedullary plasma membranes and chromaffin cells.
    Journal of neurochemistry, 1989, Volume: 53, Issue:5

    Topics: Adrenal Medulla; Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cattle; Cell Membrane; Chromaffin System; Dihydropyridines; Isradipine; Kinetics; Ouabain; Oxadiazoles; Stereoisomerism

1989
[3H]PN200-110 and [3H]ryanodine binding and reconstitution of ion channel activity with skeletal muscle membranes.
    Analytical biochemistry, 1989, Nov-15, Volume: 183, Issue:1

    Topics: Alkaloids; Animals; Calcium Channel Blockers; Calcium Channels; Chloride Channels; Chlorides; Dihydropyridines; Electrophoresis; Isradipine; Lipid Bilayers; Membrane Proteins; Membranes; Muscles; Oxadiazoles; Potassium Channels; Rabbits; Ryanodine; Sarcoplasmic Reticulum; Tritium

1989
Control of expression of the 1,4-dihydropyridine receptor in BC3H1 cells.
    Biochemical and biophysical research communications, 1988, Apr-29, Volume: 152, Issue:2

    Topics: Animals; Binding, Competitive; Calcium Channels; Cell Differentiation; Cell Line; Dihydropyridines; Isradipine; Mice; Muscles; Oxadiazoles; Peptides; Receptors, Nicotinic; Transforming Growth Factors

1988
Developmental changes of the distribution of binding sites for organic Ca2+-channel blockers in cat visual cortex.
    Experimental brain research, 1988, Volume: 70, Issue:2

    Topics: Aging; Animals; Autoradiography; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cats; Dihydropyridines; Image Processing, Computer-Assisted; Isradipine; Oxadiazoles; Receptors, Nicotinic; Visual Cortex

1988
Characterization of binding sites for two classes of calcium channel antagonists in human forebrain.
    European journal of pharmacology, 1985, Oct-29, Volume: 117, Issue:1

    Topics: Aniline Compounds; Autoradiography; Binding Sites; Brain; Calcium Channel Blockers; Dihydropyridines; Humans; In Vitro Techniques; Isradipine; Kinetics; Membranes; Oxadiazoles; Pyridines

1985
Characterization of dihydropyridine binding sites in the rat brain: hypertension and age-dependent modulation of [3H](+)-PN 200-110 binding.
    Brain research, 1987, May-26, Volume: 412, Issue:1

    Topics: Aging; Animals; Binding Sites; Brain; Calcium Channel Blockers; Dihydropyridines; Hypertension; Isradipine; Male; Oxadiazoles; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Tritium

1987
A novel high affinity class of Ca2+ channel blockers.
    Molecular pharmacology, 1988, Volume: 33, Issue:4

    Topics: Animals; Bepridil; Binding Sites; Calcium Channel Blockers; Cell Line; Dihydropyridines; Fluspirilene; Isradipine; Kinetics; Muscles; Oxadiazoles; Piperidines; Pyrrolidines; Rabbits; Rats; Structure-Activity Relationship; Thiazines; Verapamil

1988
Effect of divalent cation chelation on dihydropyridine binding in isolated cardiac sarcolemma vesicles.
    Biochimica et biophysica acta, 1988, Aug-18, Volume: 943, Issue:2

    Topics: Animals; Calcimycin; Calcium; Cations, Divalent; Dihydropyridines; Dogs; Edetic Acid; Hydrogen-Ion Concentration; Isradipine; Magnesium; Myocardium; Nitrendipine; Ouabain; Oxadiazoles; Phosphates; Sarcolemma

1988
The 1,4-dihydropyridine receptor associated with the skeletal muscle voltage-dependent Ca2+ channel. Purification and subunit composition.
    The Journal of biological chemistry, 1985, Nov-15, Volume: 260, Issue:26

    Topics: Animals; Anura; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Chickens; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Dihydropyridines; Electrophoresis, Polyacrylamide Gel; Isradipine; Microsomes; Molecular Weight; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Solubility

1985
(-)-[3H] desmethoxyverapamil labels multiple calcium channel modulator receptors in brain and skeletal muscle membranes: differentiation by temperature and dihydropyridines.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Animals; Brain Chemistry; Calcium; Calcium Channels; Cell Membrane; Dihydropyridines; Female; Isradipine; Kinetics; Male; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Stereoisomerism; Temperature; Tritium; Verapamil

1986
Short-term regulation of neuronal calcium channels by depolarization.
    Annals of the New York Academy of Sciences, 1995, Sep-15, Volume: 765

    Topics: Animals; Blotting, Northern; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Down-Regulation; Homeostasis; Ion Channel Gating; Isradipine; Membrane Potentials; Membrane Proteins; Models, Biological; N-Methylscopolamine; Neurons; Potassium; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives; Up-Regulation

1995
Glucocorticoid actions on synaptic plasma membranes: modulation of dihydropyridine-sensitive calcium channels.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:2

    Topics: Adenosine Triphosphate; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Membrane; Cerebral Cortex; Cyclic AMP; Dihydropyridines; Glucocorticoids; Isradipine; Kinetics; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Steroids; Synapses; Synaptosomes

1995
Biochemical characterization of ethanol actions on dihydropyridine-sensitive calcium channels in brain synaptosomes.
    Biochemical pharmacology, 1995, Nov-09, Volume: 50, Issue:10

    Topics: Adenosine Triphosphate; Alcoholism; Animals; Binding Sites; Brain; Calcium Channel Blockers; Calcium Channels; Cyclic AMP; Dihydropyridines; Ethanol; Isradipine; Magnesium; Male; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Synaptosomes; Tritium

1995
Single calcium channel behavior in native skeletal muscle.
    The Journal of general physiology, 1995, Volume: 105, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium Compounds; Cadmium; Cadmium Chloride; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chlorides; Dihydropyridines; Electrophysiology; Isradipine; Lanthanum; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Patch-Clamp Techniques

1995
Effects of tetrandrine on left ventricle hypertrophy in deoxycorticosterone acetate-salt hypertensive rats.
    European journal of pharmacology, 1995, May-04, Volume: 278, Issue:1

    Topics: Alkaloids; Animals; Antihypertensive Agents; Benzylisoquinolines; Binding, Competitive; Blood Pressure; Body Weight; Calcium; Desoxycorticosterone; Dihydropyridines; Disease Models, Animal; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Isradipine; Male; Mitochondria, Heart; Organ Size; Radioligand Assay; Random Allocation; Rats; Rats, Sprague-Dawley

1995
Autocrine production of endothelin-1 participates in the glucocorticoid-induced Ca2+ influx into vascular smooth muscle cells.
    Biochemical and biophysical research communications, 1995, Mar-08, Volume: 208, Issue:1

    Topics: Animals; Aorta; Azepines; Biological Transport; Calcium; Carbon Radioisotopes; Cell Line; Dexamethasone; Dihydropyridines; Endothelin Receptor Antagonists; Endothelins; Indoles; Isradipine; Kinetics; Muscle, Smooth, Vascular; Rats; Receptors, Endothelin

1995
Canine myocardial dihydropyridine binding sites: a positron emission tomographic study with the calcium channel inhibitor 11C-S11568.
    Life sciences, 1994, Volume: 55, Issue:19

    Topics: Animals; Binding Sites; Blood Pressure; Calcium Channel Blockers; Carbon Radioisotopes; Coronary Vessels; Dihydropyridines; Dogs; Female; Heart; Heart Rate; Isradipine; Myocardium; Tomography, Emission-Computed

1994
Modulation of L-type Ca2+ channels in clonal rat pituitary cells by membrane depolarization.
    Molecular pharmacology, 1994, Volume: 45, Issue:6

    Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Dihydropyridines; Down-Regulation; Isradipine; Kinetics; Membrane Potentials; Pituitary Gland, Anterior; Rats

1994
Decreased density of binding sites for the Ca2+ channel antagonist [3H]isradipine after denervation of rat vas deferens.
    European journal of pharmacology, 1994, May-02, Volume: 256, Issue:3

    Topics: Animals; Binding Sites; Calcium Channels; Denervation; Dihydropyridines; Isradipine; Male; Muscle Contraction; Potassium Chloride; Rats; Rats, Wistar; Vas Deferens

1994
Dihydropyridine ligand binding decreases earlier in adolescent than in infant swine after global cerebral ischemia.
    Stroke, 1994, Volume: 25, Issue:10

    Topics: Aging; Animals; Blood Pressure; Brain Ischemia; Calcium Channels; Caudate Nucleus; Cerebral Cortex; Dihydropyridines; Hippocampus; Isradipine; Ligands; Membrane Proteins; Nitrendipine; Protein Binding; Swine; Synaptosomes; Time Factors

1994
Ryanodine and dihydropyridine binding patterns and ryanodine receptor mRNA levels in myopathic hamster heart.
    The American journal of physiology, 1994, Volume: 267, Issue:3 Pt 2

    Topics: Animals; Calcium; Calcium Channels; Cardiomyopathies; Cricetinae; Dihydropyridines; Doxorubicin; Electrophysiology; Isradipine; Membrane Proteins; Muscle Proteins; Myocardium; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel

1994
In-vivo binding of (+)-[3H]PN 200-110 to peripheral tissues and brain of spontaneously hypertensive rats: effect of lacidipine.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:5

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding Sites; Brain; Calcium Channel Blockers; Cerebral Cortex; Dihydropyridines; Dose-Response Relationship, Drug; Drug Interactions; Heart; Ileum; Injections, Intravenous; Isradipine; Male; Myocardium; Rats; Rats, Inbred SHR; Tritium; Urinary Bladder

1993
Differential effects of non-peptidic tachykinin receptor antagonists on Ca2+ channels.
    European journal of pharmacology, 1994, Mar-15, Volume: 267, Issue:1

    Topics: Animals; Calcium Channels; Dihydropyridines; In Vitro Techniques; Isradipine; Muscles; Rats; Receptors, Tachykinin; Verapamil

1994
Activation of gastric mucosal calcium channels by epidermal growth factor.
    The International journal of biochemistry, 1993, Volume: 25, Issue:1

    Topics: Animals; Calcium; Calcium Channels; Calcium Radioisotopes; Chromatography, Affinity; Dihydropyridines; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Gastric Mucosa; In Vitro Techniques; Isradipine; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Tritium

1993
Transfer of 1,4-dihydropyridine sensitivity from L-type to class A (BI) calcium channels.
    Neuron, 1996, Volume: 16, Issue:1

    Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carps; Dihydropyridines; Ion Channel Gating; Isradipine; Molecular Sequence Data; omega-Agatoxin IVA; omega-Conotoxins; Peptide Fragments; Peptides; Protein Structure, Tertiary; Pyrroles; Rabbits; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Spider Venoms

1996
Molecular determinants of high affinity dihydropyridine binding in L-type calcium channels.
    The Journal of biological chemistry, 1996, Mar-08, Volume: 271, Issue:10

    Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cloning, Molecular; Dihydropyridines; Isradipine; Kinetics; Macromolecular Substances; Models, Structural; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Rabbits; Radioligand Assay; Recombinant Proteins; Structure-Activity Relationship; Tritium

1996
Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.
    Journal of medicinal chemistry, 1996, Jul-19, Volume: 39, Issue:15

    Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; CHO Cells; Cricetinae; Dihydropyridines; Enzyme Inhibitors; Guinea Pigs; Humans; Isradipine; Molecular Structure; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship

1996
The effect of oxygen free radicals on calcium current and dihydropyridine binding sites in guinea-pig ventricular myocytes.
    British journal of pharmacology, 1996, Volume: 118, Issue:5

    Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electrophysiology; Free Radicals; Fumarates; Guinea Pigs; Heart Ventricles; Isradipine; Myocardium; Patch-Clamp Techniques; Ventricular Function

1996
Dihydropyridine and ryanodine binding in ventricles from rat, trout, dogfish and hagfish.
    The Journal of experimental biology, 1996, Volume: 199, Issue:Pt 9

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Dihydropyridines; Dogfish; Female; Hagfishes; Heart Ventricles; Isradipine; Muscle Proteins; Myocardial Contraction; Myocardium; Oncorhynchus mykiss; Rats; Rats, Wistar; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Tritium

1996
Subunit composition is a major determinant in high affinity binding of a Ca2+ channel blocker.
    Molecular pharmacology, 1996, Volume: 50, Issue:5

    Topics: Aniline Compounds; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cations, Divalent; COS Cells; Dihydropyridines; Isradipine; Kinetics; Macromolecular Substances; Muscle, Skeletal; Stimulation, Chemical; Transfection

1996
Meiosis reinitiation of mussel oocytes involves L-type voltage-gated calcium channel.
    Journal of cellular biochemistry, 1997, Volume: 64, Issue:1

    Topics: Animals; Binding Sites; Bivalvia; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Membrane; Dihydropyridines; Dose-Response Relationship, Drug; Ion Channel Gating; Isradipine; Meiosis; Oocytes; Potassium Chloride; Tritium

1997
Global ischemia increases the density of voltage-dependent calcium channels in porcine cardiac sarcolemma.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:5

    Topics: 5'-Nucleotidase; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Heart Ventricles; In Vitro Techniques; Isradipine; Myocardial Ischemia; Myocardium; Sarcolemma; Swine

1997
Dissection of functional domains of the voltage-dependent Ca2+ channel alpha2delta subunit.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Sep-15, Volume: 17, Issue:18

    Topics: Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Humans; Isradipine; Kinetics; Protein Biosynthesis; Protein Conformation; Transcription, Genetic; Transfection

1997
Transfer of the high affinity dihydropyridine sensitivity from L-type To non-L-type calcium channel.
    Molecular pharmacology, 1997, Volume: 52, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Calcium Channel Blockers; Calcium Channels; Cell Line; Dihydropyridines; Humans; Isradipine; Molecular Sequence Data; Mutagenesis, Site-Directed

1997
Ca2+ channel modulation alters halothane-induced depression of ventricular myocytes.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthetics, Inhalation; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Drug Synergism; Halothane; Heart Ventricles; Isradipine; Myocardial Contraction; Myocardium; Nifedipine; Rats; Rats, Wistar; Sarcolemma; Verapamil

1998
Growth hormone regulates the distribution of L-type calcium channels in rat adipocyte membranes.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Adipocytes; Adipose Tissue; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Membrane; Cells, Cultured; Cytosol; Dihydropyridines; Epididymis; Growth Hormone; Isradipine; Kinetics; Male; Microsomes; Rats; Rats, Inbred Strains

1998
Molecular mechanism of diltiazem interaction with L-type Ca2+ channels.
    The Journal of biological chemistry, 1998, Oct-16, Volume: 273, Issue:42

    Topics: Alanine; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; DNA Mutational Analysis; Electric Conductivity; Electrophysiology; Ion Channel Gating; Isradipine; Muscle, Skeletal; Mutagenesis

1998
Reconstruction of the dihydropyridine site in a non-L-type calcium channel: the role of the IS6 segment.
    FEBS letters, 1999, May-21, Volume: 451, Issue:2

    Topics: Animals; Calcium Channels; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Electrophysiology; Inhibitory Concentration 50; Isradipine; Mutagenesis; Recombinant Fusion Proteins

1999
Effects of L-type voltage-sensitive calcium channel modulators on the discriminative stimulus effects of ethanol in rats.
    Alcoholism, clinical and experimental research, 1999, Volume: 23, Issue:5

    Topics: Animals; Calcium Channel Blockers; Conditioning, Operant; Dihydropyridines; Discrimination Learning; Ethanol; Feeding Behavior; Isradipine; Male; Nifedipine; Rats; Taste

1999
Cardiac inotropic vs. chronotropic selectivity of isradipine, nifedipine and clevidipine, a new ultrashort-acting dihydropyridine.
    European journal of pharmacology, 1999, Sep-10, Volume: 380, Issue:2-3

    Topics: Animals; Calcium Channel Blockers; Cardiotonic Agents; Coronary Circulation; Dihydropyridines; Heart Atria; Heart Block; Heart Rate; Isradipine; Male; Myocardial Contraction; Nifedipine; Pyridines; Rats; Rats, Sprague-Dawley; Systole; Ventricular Function, Left; Ventricular Pressure

1999
State- and isoform-dependent interaction of isradipine with the alpha1C L-type calcium channel.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:1

    Topics: Alternative Splicing; Barium; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Ion Transport; Isradipine; Membrane Potentials; Muscle, Smooth; Mutagenesis, Site-Directed; Myocardium; Patch-Clamp Techniques; Protein Isoforms; Transfection

2000
In vivo specific binding characteristics and pharmacokinetics of a 1,4-dihydropyridine calcium channel antagonist in the senescent mouse brain.
    Pharmaceutical research, 2000, Volume: 17, Issue:7

    Topics: Aging; Animals; Brain; Calcium Channel Blockers; Dihydropyridines; Isradipine; Male; Mice; Myocardium

2000
Abnormality of calcium channel inhibitor released from fetal membranes in preterm labor.
    American journal of obstetrics and gynecology, 2001, Volume: 184, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Extraembryonic Membranes; Female; Guinea Pigs; Humans; Isradipine; Obstetric Labor, Premature; Organ Specificity; Placenta; Pregnancy; Random Allocation; Rats; Rats, Wistar; Uterine Contraction

2001
Mechanism of dihydropyridine interaction with critical binding residues of L-type Ca2+ channel alpha 1 subunits.
    The Journal of biological chemistry, 2001, Apr-20, Volume: 276, Issue:16

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Female; Isoleucine; Isradipine; Kinetics; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Phenylalanine; Protein Structure, Secondary; Protein Subunits; Recombinant Proteins; Valine; Xenopus laevis

2001
Nifedipine-activated Ca(2+) permeability in newborn rat cortical collecting duct cells in primary culture.
    American journal of physiology. Cell physiology, 2001, Volume: 280, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Biological Transport; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cells, Cultured; Cytosol; Dihydropyridines; Diltiazem; Egtazic Acid; Gadolinium; Hydrogen Peroxide; Isradipine; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Lanthanum; Nifedipine; Protamines; Rats; Rats, Sprague-Dawley; Thapsigargin; Verapamil

2001
Functional expression and characterization of a voltage-gated CaV1.3 (alpha1D) calcium channel subunit from an insulin-secreting cell line.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:7

    Topics: Androstadienes; Animals; Barium; Calcium Channels; Calcium Channels, L-Type; Dihydropyridines; Electric Conductivity; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Female; Gene Expression; GTP-Binding Proteins; Ion Channel Gating; Isradipine; Myocardium; Neurons; Oocytes; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Receptors, Opioid, mu; Tetradecanoylphorbol Acetate; Wortmannin; Xenopus laevis

2001
Cav1.4alpha1 subunits can form slowly inactivating dihydropyridine-sensitive L-type Ca2+ channels lacking Ca2+-dependent inactivation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jul-09, Volume: 23, Issue:14

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cloning, Molecular; Dihydropyridines; Humans; Ion Channel Gating; Isradipine; Kidney; Molecular Sequence Data; Patch-Clamp Techniques; Protein Subunits; Sequence Homology, Amino Acid; Transfection

2003
Key roles of Phe1112 and Ser1115 in the pore-forming IIIS5-S6 linker of L-type Ca2+ channel alpha1C subunit (CaV 1.2) in binding of dihydropyridines and action of Ca2+ channel agonists.
    Molecular pharmacology, 2003, Volume: 64, Issue:2

    Topics: Alanine; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Isradipine; Phenylalanine; Point Mutation; Protein Subunits; Pyrroles; Rats; Repetitive Sequences, Nucleic Acid; Serine

2003
Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus.
    Canadian journal of physiology and pharmacology, 2003, Volume: 81, Issue:9

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Differentiation; Dihydropyridines; Female; Hypothyroidism; In Vitro Techniques; Isradipine; Mice; Mice, Inbred C57BL; Muscle, Smooth; Thyroid Hormones; Uterine Contraction; Uterus

2003
Marrubenol interacts with the phenylalkylamine binding site of the L-type calcium channel.
    European journal of pharmacology, 2004, May-25, Volume: 492, Issue:2-3

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diterpenes; Furans; Ileum; In Vitro Techniques; Isradipine; Male; Membranes; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Radioligand Assay; Rats; Rats, Wistar; Vasodilator Agents; Verapamil

2004
Proliferation of cultured human gingival fibroblasts caused by isradipine, a dihydropyridine-derivative calcium antagonist.
    European journal of medical research, 2004, Jun-30, Volume: 9, Issue:6

    Topics: Calcium; Calcium Channel Blockers; Cell Division; Cell Line; Collagen Type I; Culture Media; Dihydropyridines; Fibroblast Growth Factors; Fibroblasts; Gingiva; Humans; Isradipine

2004
Opposite effects of a single IIIS5 mutation on phenylalkylamine and dihydropyridine interaction with L-type Ca2+ channels.
    The Journal of biological chemistry, 2004, Dec-31, Volume: 279, Issue:53

    Topics: Animals; Brain; Calcium; Calcium Channels; Calcium Channels, L-Type; Carrier Proteins; Cell Membrane; Dihydropyridines; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Gallopamil; Homozygote; In Situ Hybridization; Isradipine; Kinetics; Mice; Mice, Transgenic; Microsomes; Models, Biological; Mutation; Oocytes; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; RNA, Complementary; Steroid Isomerases; Tyrosine; Verapamil; Xenopus laevis

2004