isoxazoles has been researched along with tyrosine in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (11.43) | 18.7374 |
| 1990's | 7 (20.00) | 18.2507 |
| 2000's | 12 (34.29) | 29.6817 |
| 2010's | 10 (28.57) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Cross, SS; Gunasekera, SP | 1 |
| Akers, W; Ballaron, SJ; DeYoung, LM; Falciano, V; Goldsmith, LA | 1 |
| Berger, R; Schierbeek, H | 1 |
| Gromet-Elhanan, Z; Khananshvili, D | 1 |
| Bendtzen, K; Dinarello, CA; Wolff, SM | 1 |
| Homandberg, GA; Minor, ST; Peanasky, RJ | 1 |
| Cherwinski, HM; Devens, B; McCarley, D; Ransom, JT; Schatzman, R | 1 |
| Hamano, S; Morita, K; Oka, M; Teraoka, K | 1 |
| Blinder, L; Chong, AS; Gong, H; Shen, J; Williams, JW; Xu, X | 1 |
| Chong, AS; Finnegan, A; Gong, H; Jäck, HM; Siemasko, K; Williams, JW | 1 |
| Blinder, L; Chong, AS; Huang, W; Mall, JW; Myers, JA; Saclarides, TJ; Shen, J; Williams, JW; Xu, X | 1 |
| Bozarth, JM; Forsythe, MS; Mousa, SA; Slee, A | 1 |
| Caron, A; Merhi, Y; Mousa, SA; Théorêt, JF | 1 |
| Dimitrova, P; Herrmann, ML; Kalden, JR; Schleyerbach, R; Schulze-Koops, H; Skapenko, A | 1 |
| Barbera, FA; Dorsam, RT; Feuerstein, GZ; Friedman, SM; Gibbs, S; Lauver, A; Savion, N; Varon, D; Wang, H; Wang, X | 1 |
| Billheimer, JT; He, B; Kieras, CJ; Pedicord, DL; Seiffert, D; Stern, AM | 1 |
| Dale, GL; Hamilton, SF; Miller, MW; Thompson, CA | 1 |
| Berlinck, RG; de Oliveira, MF; König, GM; Molinski, TF; Rogers, EW | 1 |
| Connor, JH; Connor, RF; Hantgan, RR; Mousa, SA; Stahle, MC | 1 |
| Aguirre, N; de la Torre, R; Goñi-Allo, B; Hervias, I; Lasheras, B; Mathúna, BO; Puerta, E | 1 |
| Liu, Y; Xu, J; Zhang, GY | 1 |
| Benson, GM; Bleicher, K; Chen, L; Feng, S; Grether, U; Hong, D; Kuhn, B; Martin, RE; Plancher, JM; Richter, H; Rudolph, MG; Wang, Z; Yang, M; Zhang, Z | 1 |
| Hantgan, RR; Stahle, MC | 1 |
| Andrews, KT; Birrell, GW; Camp, D; Davis, RA; Quinn, RJ; Tran, TL; Xu, M | 1 |
| Deng, P; Liao, XJ; Xu, SH | 1 |
| Banner, DW; Benz, J; Diederich, F; Haap, W; Holland, MC; Kaib, PS; Kuster, O; Mary, JL; Salonen, LM; Schweizer, WB | 1 |
| Gochfeld, DJ; Kamel, HN; Olson, JB; Thacker, RW | 1 |
| Avery, VM; Camp, D; Davis, RA; Feng, Y; Quinn, RJ; Shelper, T; Sykes, ML; Xu, M | 1 |
| Dai, J; Kelly, M; Parrish, SM; Turkson, J; Williams, P; Yip, MLR; Yoshida, WY | 1 |
| Andersen, RJ; Appolinario, LR; Berlinck, RG; Eustaquio, AS; Ferreira, AG; Fróes, AM; Ióca, LP; Leomil, L; Nicacio, KJ; Thompson, CC; Thompson, FL; Williams, DE | 1 |
| Cho, ML; Jhun, JY; Kim, EK; Lee, HJ; Lee, WS; Min, JK; Moon, SJ; Park, SH | 1 |
| Byun, S; Guo, G; Kemper, B; Kemper, JK; Kim, DH; Kim, YC; Kong, B; Ryerson, D; Sun, H; Xu, HE; Yau, P | 1 |
| Bechmann, N; Binnewerg, B; Bornstein, SR; Ehrlich, H; Erpenbeck, D; Fromont, J; Fursov, A; Gelinsky, M; Giovine, M; Guan, K; Ivanenko, VN; Joseph, Y; Kovalchuk, V; Martinovic, R; Muzychka, L; Petrenko, I; Schubert, M; Smolii, OB; Springer, A; Tsurkan, MV; Voronkina, A; Wysokowski, M | 1 |
| Bechmann, N; Bornstein, SR; Drechsel, A; Ehrlich, H; Helm, J; Pantovic, S | 1 |
| Heo, JD; Jeong, EJ; Ji, YK; Kim, NH; Kim, YN; Lee, SM; Rho, JR; Tu, NV | 1 |
35 other study(ies) available for isoxazoles and tyrosine
| Article | Year |
|---|---|
Fistularin 3 and 11-ketofistularin 3. Feline leukemia virus active bromotyrosine metabolites from the marine sponge Aplysina archeri.
Topics: Animals; Antiviral Agents; Isoxazoles; Leukemia Virus, Feline; Magnetic Resonance Spectroscopy; Porifera; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured; Tyrosine; Virus Replication | 1992 |
Inhibition of human epidermal transglutaminases in vitro and in vivo by tyrosinamidomethyl dihydrohaloisoxazoles.
Topics: Cells, Cultured; Epidermis; Humans; Isoxazoles; Keratinocytes; Transglutaminases; Tretinoin; Tyrosine | 1991 |
Determination of succinylacetone and succinylacetoacetate in physiological samples as the common product 5(3)-methyl-3(5)-isoxazole propionic acid using an isotope dilution method and mass spectrometry.
Topics: Acetoacetates; Gas Chromatography-Mass Spectrometry; Heptanoates; Heptanoic Acids; Humans; Isotopes; Isoxazoles; Mass Spectrometry; Nitrogen Isotopes; Oxazoles; Tyrosine | 1989 |
Evidence that the Mg-dependent low-affinity binding site for ATP and Pi demonstrated on the isolated beta subunit of the F0.F1 ATP synthase is a catalytic site.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding Sites; Dicyclohexylcarbodiimide; Diethyl Pyrocarbonate; Histidine; Isoxazoles; Magnesium; Phosphates; Phosphorylation; Proton-Translocating ATPases; Rhodospirillum; Tyrosine | 1985 |
Studies on the active site of human leukocytic pyrogen.
Topics: Arginine; Binding Sites; Biotransformation; Carboxypeptidase B; Carboxypeptidases; Halogens; Humans; Indicators and Reagents; Interleukin-1; Isoxazoles; Phenylmethylsulfonyl Fluoride; Proteins; Tyrosine | 1982 |
Modification of the carboxypeptidase A active site residue Glu-270 prevents interaction with a protein protease inhibitor from Ascaris.
Topics: Animals; Ascaris; Benzenesulfonates; Binding Sites; Carboxypeptidases; Carboxypeptidases A; Glutamates; Hydrogen-Ion Concentration; Isoxazoles; Oxazoles; Protease Inhibitors; Protein Binding; Structure-Activity Relationship; Tetranitromethane; Tyrosine | 1980 |
The immunosuppressant leflunomide inhibits lymphocyte progression through cell cycle by a novel mechanism.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Calcium; Cell Cycle; Female; Immunosuppressive Agents; In Vitro Techniques; Interleukin-2; Isoxazoles; Leflunomide; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, Interleukin-2; Tumor Cells, Cultured; Tyrosine | 1995 |
Lack of relationship between gamma-glutamyl transpeptidase and tyrosine transport in cultured bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Animals; Biological Transport; Cattle; Cells, Cultured; gamma-Glutamyltransferase; Hippurates; Isoxazoles; Tyrosine | 1994 |
Control of lymphoproliferative and autoimmune disease in MRL-lpr/lpr mice by brequinar sodium: mechanisms of action.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Biphenyl Compounds; Cytidine Triphosphate; Female; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lymphoproliferative Disorders; Mice; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Phosphorylation; Tyrosine; Uridine; Uridine Triphosphate | 1997 |
Inhibition of JAK3 and STAT6 tyrosine phosphorylation by the immunosuppressive drug leflunomide leads to a block in IgG1 production.
Topics: Animals; B-Lymphocytes; Binding, Competitive; DNA-Binding Proteins; Growth Inhibitors; Immunoglobulin G; Immunosuppressive Agents; Interleukin-4; Isoxazoles; Janus Kinase 3; Leflunomide; Lipopolysaccharides; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; STAT6 Transcription Factor; Trans-Activators; Tyrosine; Uridine | 1998 |
In vitro and in vivo antitumor activity of a novel immunomodulatory drug, leflunomide: mechanisms of action.
Topics: 3T3 Cells; Adjuvants, Immunologic; Aniline Compounds; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Crotonates; Drug Screening Assays, Antitumor; ErbB Receptors; Female; Glioma; Hydroxybutyrates; Immunosuppressive Agents; Isoxazoles; Leflunomide; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nitriles; Phosphorylation; Pyrimidine Nucleotides; Receptors, Growth Factor; Receptors, Platelet-Derived Growth Factor; Toluidines; Tumor Cells, Cultured; Tyrosine | 1999 |
Differential antiplatelet efficacy for various GPIIb/IIIa antagonists: role of plasma calcium levels.
Topics: Abciximab; Alanine; Amidines; Analysis of Variance; Antibodies, Monoclonal; Anticoagulants; Blood Platelets; Calcium; Citric Acid; Eptifibatide; Fibrinogen; Heparin; Humans; Immunoglobulin Fab Fragments; Iodine Radioisotopes; Isoxazoles; Peptides; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Pyrrolidines; Tirofiban; Tyrosine | 2000 |
Anti-platelet effects of GPIIb/IIIa and P-selectin antagonism, platelet activation, and binding to neutrophils.
Topics: Abciximab; Amidines; Analysis of Variance; Antibodies, Monoclonal; Cells, Cultured; Humans; Immunoglobulin Fab Fragments; Isoxazoles; Neutrophils; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Tirofiban; Tyrosine | 2002 |
Restriction of de novo pyrimidine biosynthesis inhibits Th1 cell activation and promotes Th2 cell differentiation.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Female; Humans; Immunologic Memory; Immunosuppressive Agents; Interphase; Intracellular Fluid; Isoxazoles; Leflunomide; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phosphorylation; Pyrimidines; Stem Cells; Th1 Cells; Th2 Cells; Tyrosine; Uridine Triphosphate | 2002 |
Comparative analysis of various platelet glycoprotein IIb/IIIa antagonists on shear-induced platelet activation and adhesion.
Topics: Abciximab; Alanine; Amidines; Analysis of Variance; Antibodies, Monoclonal; Anticoagulants; Aspirin; Cell Aggregation; Dose-Response Relationship, Drug; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Isoxazoles; Peptides; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Rheology; Shear Strength; Temperature; Tirofiban; Tyrosine | 2002 |
Regulation of clot retraction by glycoprotein IIb/IIIa antagonists.
Topics: Abciximab; Alanine; Amidines; Antibodies, Monoclonal; Blood Platelets; Clot Retraction; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Isoxazoles; Phosphorylation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Sulfonamides; Tyrosine | 2002 |
Glycoprotein IIb/IIIa inhibitors increase COAT-platelet production in vitro.
Topics: Antibodies, Monoclonal; Blood Platelets; Collagen; Eptifibatide; Fibrinogen; Humans; Isoxazoles; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Sulfonamides; Thrombin; Tirofiban; Tyrosine | 2004 |
Stereochemical heterogeneity in Verongid sponge metabolites. Absolute stereochemistry of (+)-fistularin-3 and (+)-11-epi-fistularin-3 by microscale LCMS-Marfey's analysis.
Topics: Alanine; Animals; Australia; Brazil; Dinitrobenzenes; Florida; Isoxazoles; Mixed Function Oxygenases; Molecular Structure; Porifera; Stereoisomerism; Tyrosine | 2005 |
AlphaIIbbeta3 priming and clustering by orally active and intravenous integrin antagonists.
Topics: Administration, Oral; Alanine; Amidines; Binding, Competitive; Blood Platelets; Dimerization; Dose-Response Relationship, Drug; Eptifibatide; Female; Fibrinogen; Humans; In Vitro Techniques; Injections, Intravenous; Intercellular Signaling Peptides and Proteins; Isoxazoles; Kinetics; Male; Models, Molecular; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Conformation; Pyrrolidines; Reference Values; Structure-Activity Relationship; Tirofiban; Tyrosine | 2007 |
On the role of tyrosine and peripheral metabolism in 3,4-methylenedioxymethamphetamine-induced serotonin neurotoxicity in rats.
Topics: Analysis of Variance; Animals; Antimetabolites; Area Under Curve; Body Temperature; Brain; Catechols; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hydroxyindoleacetic Acid; Isoxazoles; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Nitriles; Protein Binding; Rats; Rats, Wistar; Serotonin; Time Factors; Tyrosine | 2008 |
Neuroprotection of GluR5-containing kainate receptor activation against ischemic brain injury through decreasing tyrosine phosphorylation of N-methyl-D-aspartate receptors mediated by Src kinase.
Topics: Animals; Brain; Disks Large Homolog 4 Protein; Intracellular Signaling Peptides and Proteins; Ischemia; Isoxazoles; Male; Membrane Proteins; Patch-Clamp Techniques; Phosphorylation; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Tyrosine | 2008 |
Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist.
Topics: Binding Sites; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Humans; Hydrogen Bonding; Isoxazoles; Ligands; Models, Chemical; Protein Binding; Receptors, Cytoplasmic and Nuclear; Serine; Tyrosine | 2009 |
Integrin priming dynamics: mechanisms of integrin antagonist-promoted alphaIIbbeta3:PAC-1 molecular recognition.
Topics: Amidines; Dual Specificity Phosphatase 2; Eptifibatide; Integrins; Intercellular Signaling Peptides and Proteins; Isoxazoles; Models, Molecular; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Thermodynamics; Tirofiban; Tyrosine | 2009 |
Psammaplysin H, a new antimalarial bromotyrosine alkaloid from a marine sponge of the genus Pseudoceratina.
Topics: Alkaloids; Animals; Antimalarials; Cell Line; Humans; Isoxazoles; Malaria, Falciparum; Oxepins; Plasmodium falciparum; Porifera; Tyrosine | 2011 |
[Isolation and identification of brominated alkaloids from the sponge Ircinia sp].
Topics: Alkaloids; Animals; China; Hydrocarbons, Brominated; Isoxazoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Oceans and Seas; Porifera; Tyrosine | 2011 |
Molecular recognition at the active site of factor Xa: cation-π interactions, stacking on planar peptide surfaces, and replacement of structural water.
Topics: Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Factor Xa; Factor Xa Inhibitors; Humans; Isoxazoles; Molecular Conformation; Peptides; Serine Endopeptidases; Stereoisomerism; Thermodynamics; Thiophenes; Tyrosine; Water | 2012 |
Trade-offs in defensive metabolite production but not ecological function in healthy and diseased sponges.
Topics: Animal Diseases; Animals; Anti-Bacterial Agents; Bacteria; Caribbean Region; Chromatography, High Pressure Liquid; Feeding Behavior; Isoxazoles; Oxazoles; Porifera; Spiro Compounds; Tetraodontiformes; Tyrosine | 2012 |
Ianthelliformisamines A-C, antibacterial bromotyrosine-derived metabolites from the marine sponge Suberea ianthelliformis.
Topics: Acinetobacter; Animals; Anti-Bacterial Agents; Isoxazoles; Marine Biology; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenethylamines; Porifera; Pseudomonas aeruginosa; Staphylococcus; Tyrosine | 2012 |
Bromotyrosine-derived metabolites from an Indonesian marine sponge in the family Aplysinellidae (Order Verongiida).
Topics: Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents; Aspartic Acid Endopeptidases; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Isoxazoles; Mice; NIH 3T3 Cells; Oximes; Porifera; Protease Inhibitors; Tyrosine | 2016 |
Cultures of the Marine Bacterium Pseudovibrio denitrificans Ab134 Produce Bromotyrosine-Derived Alkaloids Previously Only Isolated from Marine Sponges.
Topics: Alkaloids; Animals; Bacteria; Brazil; Isoxazoles; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oceans and Seas; Porifera; Tyrosine | 2017 |
The active metabolite of leflunomide, A77 1726, attenuates inflammatory arthritis in mice with spontaneous arthritis via induction of heme oxygenase-1.
Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Differentiation; Crotonates; Forkhead Transcription Factors; Heme Oxygenase-1; Humans; Hydroxybutyrates; Inflammation; Isoxazoles; Jurkat Cells; Leflunomide; Mice, Inbred BALB C; Mice, Inbred C57BL; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Nitriles; Oxidative Stress; Signal Transduction; Spleen; Th17 Cells; Toluidines; Tyrosine | 2017 |
Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis.
Topics: 1-Naphthylisothiocyanate; Animals; Bile Acids and Salts; Biomarkers; Cell Nucleus; Disease Models, Animal; Fibroblast Growth Factors; Healthy Volunteers; Hepatocytes; Humans; Intestinal Mucosa; Isoxazoles; Liver; Liver Cirrhosis, Biliary; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phosphorylation; Postprandial Period; Primary Cell Culture; Receptors, Cytoplasmic and Nuclear; Signal Transduction; src-Family Kinases; Tyrosine | 2018 |
Naturally Drug-Loaded Chitin: Isolation and Applications.
Topics: Animals; Anti-Bacterial Agents; Aquatic Organisms; Chitin; Cytoskeleton; Decamethonium Compounds; Drug Carriers; Hydrocarbons, Brominated; Isoxazoles; Microbial Sensitivity Tests; Peptides, Cyclic; Porifera; Spectroscopy, Fourier Transform Infrared; Staphylococcus aureus; Tyrosine | 2019 |
Anti-Tumor Activity vs. Normal Cell Toxicity: Therapeutic Potential of the Bromotyrosines Aerothionin and Homoaerothionin In Vitro.
Topics: Animals; Antineoplastic Agents; BALB 3T3 Cells; Cell Line, Tumor; Disease Models, Animal; Isoxazoles; Mice; Porifera; Spiro Compounds; Tyrosine | 2020 |
Stereochemical Determination of Fistularins Isolated from the Marine Sponge
Topics: Animals; Anti-Inflammatory Agents; Caco-2 Cells; Coculture Techniques; Cytokines; Dinoprostone; Humans; Inflammation Mediators; Inflammatory Bowel Diseases; Isoxazoles; Molecular Structure; NF-kappa B; Nitric Oxide; Porifera; Signal Transduction; Stereoisomerism; Structure-Activity Relationship; THP-1 Cells; Tyrosine | 2021 |