Page last updated: 2024-08-21

isoxazoles and thromboxane b2

isoxazoles has been researched along with thromboxane b2 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's6 (75.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Breslow, R; Cheng, JB; Conklyn, MJ; Pillar, JS; Shirley, JT; Showell, HJ1
Kent, JD; Leese, PT; Recker, DP; Talwalker, S1
Kent, JD; Leese, PT; Recker, DP1
Di Nunno, L; Patrignani, P; Scilimati, A; Tacconelli, S; Vitale, P1
Munsterhjelm, E; Neuvonen, PJ; Niemi, TT; Rosenberg, PH; Ylikorkala, O1
Arabmotlagh, M; Cheung, R; Geisslinger, G; Graff, J; Harder, S1
Ahmad, M; Graham, SH; Liu, H; Rose, ME; Zhang, Y1
Archer, TM; Mackin, AJ; Thomason, JM; Wills, RW1

Trials

5 trial(s) available for isoxazoles and thromboxane b2

ArticleYear
Valdecoxib does not impair platelet function.
    The American journal of emergency medicine, 2002, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Bleeding Time; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Naproxen; Platelet Aggregation; Statistics, Nonparametric; Sulfonamides; Thromboxane B2

2002
The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial.
    Journal of clinical pharmacology, 2003, Volume: 43, Issue:5

    Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Arachidonic Acid; Bleeding Time; Blood Platelets; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Ibuprofen; Isoenzymes; Isoxazoles; Male; Membrane Proteins; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2

2003
Influence on platelet aggregation of i.v. parecoxib and acetaminophen in healthy volunteers.
    British journal of anaesthesia, 2006, Volume: 97, Issue:2

    Topics: Acetaminophen; Adenosine Diphosphate; Adult; Analgesics, Non-Narcotic; Arachidonic Acid; Blood Platelets; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Epinephrine; Humans; Infusions, Intravenous; Isoxazoles; Male; Platelet Aggregation; Thromboxane B2

2006
Effects of parecoxib and dipyrone on platelet aggregation in patients undergoing meniscectomy: a double-blind, randomized, parallel-group study.
    Clinical therapeutics, 2007, Volume: 29, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Child; Cyclooxygenase Inhibitors; Dipyrone; Double-Blind Method; Drug Therapy, Combination; Enoxaparin; Enzyme-Linked Immunosorbent Assay; Female; Humans; Isoxazoles; Male; Middle Aged; Pain, Postoperative; Platelet Aggregation; Thromboxane B2

2007
Effects of immunosuppressive agents on the hemostatic system in normal dogs.
    Journal of veterinary internal medicine, 2018, Volume: 32, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azathioprine; Blood Coagulation; Blood Platelets; Creatinine; Cross-Over Studies; Cyclosporine; Dogs; Female; Hemostasis; Immunosuppressive Agents; Isoxazoles; Leflunomide; Male; Mycophenolic Acid; Platelet Aggregation; Platelet Count; Prednisone; Thromboxane B2

2018

Other Studies

3 other study(ies) available for isoxazoles and thromboxane b2

ArticleYear
Evidence that peptidoleukotriene is a prerequisite for antigen-dependent thromboxane synthesis in IgG1-passively sensitized guinea pig lungs.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Animals; Antigens; Guinea Pigs; Immunoglobulin G; Indazoles; Isoxazoles; Lung; Male; Platelet Activating Factor; SRS-A; Thromboxane B2

1990
Novel synthesis of 3,4-diarylisoxazole analogues of valdecoxib: reversal cyclooxygenase-2 selectivity by sulfonamide group removal.
    Journal of medicinal chemistry, 2004, Sep-23, Volume: 47, Issue:20

    Topics: Adult; Biochemistry; Blood; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Inhibitory Concentration 50; Isoenzymes; Isoxazoles; Lipopolysaccharides; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Sulfonamides; Thromboxane B2

2004
Prolonged opportunity for neuroprotection in experimental stroke with selective blockade of cyclooxygenase-2 activity.
    Brain research, 2009, Jul-07, Volume: 1279

    Topics: Animals; Blood Pressure; Body Temperature; Brain; Cerebrovascular Circulation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Hippocampus; Infarction, Middle Cerebral Artery; Isoxazoles; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sulfonamides; Thromboxane B2; Time Factors

2009