Page last updated: 2024-08-21

isoxazoles and roxifiban

isoxazoles has been researched along with roxifiban in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (10.81)	18.2507
2000's	32 (86.49)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (2.70)	2.80

Authors

Authors	Studies
Foris, CM; Harlow, RL; Li, H; Li, ZG; Ma, P; Maurin, MB; Toby, BH; Vickery, RD	2
Boucher, RJ; Brockson, RW; Miyawa, JH; Williams, RC	1
Kapil, R; Mousa, SA; Mu, DX	1
Lloyd, DK; Reilly, K; Shamrock, WF	1
Boucher, RJ; Williams, RC	1
Forsythe, MS; Khurana, S; Mousa, SA	1
Bozarth, JM; Forsythe, MS; Mousa, SA; Slee, A	1
Foris, CM; Harlow, RL; Li, ZG; Liang, L; Liu, J; Maurin, MB; Olson, RE; Sielecki, TM; Vickery, RD	1
Mousa, SA	1
Batt, DG; Daneker, WF; Houghton, GC; Jadhav, PK	1
Christ, DD; Diamond, S; Gan, L; Mutlib, AE; Nemeth, G; Shockcor, J; Way, R	1
Bozarth, JM; Mousa, SA; Naik, UP; Slee, A	1
Abulencia, JP; Konstantopoulos, K; McCarty, OJ; Mousa, SA; Turner, NA	1
Billheimer, JT; Bradley, JD; Cromley, DA; Daly, RN; Dicker, IB; Godonis, HE; Gorko, MA; Grimminger, LC; He, B; Hollis, GF; Kieras, CJ; Pedicord, DL; Seiffert, D; Spitz, SM; Stern, AM; Thomas, BE; Wynn, R; Zolotarjova, NI	1
Cain, VA; Ebling, W; Fossler, MJ; Kornhauser, DM; Ma, S; Mondick, JT; Pieniaszek, HJ; Sy, SK	1
Caron, A; Merhi, Y; Mousa, SA; Théorêt, JF	1
Maurin, MB; Nemeth, GA; Vickery, RD	1
Feuerstein, GZ; Wang, X; Zondlo, SC	1
Barrett, YC; Billheimer, JT; Cromley, DA; Daly, RN; Ebling, W; He, B; Hollis, GF; Hua, TA; Kieras, CJ; Pedicord, DL; Pieniaszek, HJ; Rossi, RJ; Seiffert, D; Sferruzza, A; Stein, RB; Stern, AM; Wynn, R	1
Campbell, GC; Everlof, JG; Foris, CM; Maurin, MB; Nemeth, GA; Rabel, SR; Rowe, SM; Vickery, RD	1
Barbera, FA; Dorsam, RT; Feuerstein, GZ; Friedman, SM; Gibbs, S; Lauver, A; Savion, N; Varon, D; Wang, H; Wang, X	1
Barrett, JS; Ebling, WF; Fossler, MJ; Garner, D; Kornhauser, D; Ma, S; Mondick, J; Pieniaszek, HJ; Quon, CY	1
Barrett, YC; Davidson, AF; Olson, RE; Pieniaszek, HJ; Pinto, DJ; Reilly, TM; Walton, HL	1
Billheimer, JT; He, B; Seiffert, D; Spitz, SM; Stern, AM	1
Billheimer, JT; He, B; Kieras, CJ; Pedicord, DL; Seiffert, D; Stern, AM	1
Billheimer, JT; Breth, L; Dicker, I; Hollis, GF; O'Neil, K; Pedicord, DL; Seiffert, D; Stern, AM; Wynn, R	1
Emm, TA; Jiao, Q; Lloyd, TL; Mutlib, A; Pieniaszek, HJ; Shi, G; Sy, SK; Unger, SE; Wernicki, A	1
Bradley, JD; Cain, VA; Feuerstein, GZ; Hua, TA; Kornhauser, DM; Martin, DE; Munzer, DA; Seiffert, D; Stern, AM; Tchinnes, MA; Thomas, BE	1
Gurbel, PA; Malinin, AI; O'connor, CM; Serebruany, VL	1
Cain, VA; Daly, RN; Ebling, W; Gussak, I; Kopecky, SL; Murphy, J; Pieniaszek, HJ; Simonson, K; Sy, SK; Wilcox, RA; Williams, B; Wright, RS	1
Bozarth, JM; Feuerstein, GZ; Mousa, SA; Seiffert, D	1
Connor, JH; Connor, RF; Hantgan, RR; Mousa, SA; Stahle, MC	1
Barrett, YC; Billheimer, J; Ebling, W; Pieniaszek, H; Seiffert, D	1
Hantgan, RR; Stahle, MC	1
Carreira, EM; Sandmeier, T	1

Trials

7 trial(s) available for isoxazoles and roxifiban

Article	Year
Safety, tolerability, pharmacokinetics, and time course of pharmacologic response of the active metabolite of roxifiban, XV459, a glycoprotein IIb/IIIa antagonist, following oral administration in healthy volunteers. Journal of clinical pharmacology, 2002, Volume: 42, Issue:7 Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Amidines; Amino Acids; Area Under Curve; Aspirin; Bleeding Time; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Hydrolysis; Isoxazoles; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Time Factors	2002
Prospective testing for drug-dependent antibodies reduces the incidence of thrombocytopenia observed with the small molecule glycoprotein IIb/IIIa antagonist roxifiban: implications for the etiology of thrombocytopenia. Blood, 2003, Jan-01, Volume: 101, Issue:1 Topics: Amidines; Autoantibodies; Blood Platelets; Humans; Incidence; Isoxazoles; Platelet Glycoprotein GPIIb-IIIa Complex; Retrospective Studies; Thrombocytopenia; Time Factors; Vascular Diseases	2003
Integrated pharmacokinetic/pharmacodynamic model of XV459, a potent and specific GPIIb/IIIa inhibitor, in healthy male volunteers. Journal of clinical pharmacology, 2002, Volume: 42, Issue:12 Topics: Administration, Oral; Aged; Amidines; Amino Acids; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Humans; Isoxazoles; Middle Aged; Models, Biological; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs	2002
Effects of the glycoprotein IIb/IIIa antagonist Roxifiban on P-selectin expression, fibrinogen binding, and microaggregate formation in a phase I dose-finding study: no evidence for platelet activation during treatment with a glycoprotein IIb/IIIa antagon Platelets, 2003, Volume: 14, Issue:3 Topics: Adenosine Diphosphate; Adult; Amidines; Biomarkers; Dose-Response Relationship, Drug; Female; Fibrinogen; Humans; Isoxazoles; Male; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Receptors, Thrombin	2003
Effects of roxifiban on platelet aggregation and major receptor expression in patients with coronary artery disease for the Roxifiban Oral Compound Kinetics Evaluation Trial-I (ROCKET-I Platelet Substudy). American heart journal, 2003, Volume: 146, Issue:1 Topics: Amidines; Aspirin; Coronary Disease; Coronary Thrombosis; Double-Blind Method; Female; Flow Cytometry; Humans; Isoxazoles; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Statistics, Nonparametric; Thrombolytic Therapy	2003
The use of roxifiban (DMP754), a novel oral platelet glycoprotein IIb/IIIa receptor inhibitor, in patients with stable coronary artery disease. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2003, Volume: 3, Issue:2 Topics: Aged; Amidines; Angina Pectoris; Bleeding Time; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex	2003
Using thrombelastography to determine the efficacy of the platelet glycoprotein IIb/IIIa antagonist, roxifiban, on platelet/fibrin-mediated clot dynamics in humans. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2005, Volume: 16, Issue:3 Topics: Amidines; Aspirin; Blood Coagulation; Calcium Chloride; Cross-Over Studies; Fibrin; Humans; Isoxazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Reference Values; Thrombelastography	2005

Other Studies

30 other study(ies) available for isoxazoles and roxifiban

Article	Year
Polymorph determination for the GP IIb/IIIa antagonist, roxifiban, using a combination of electron diffraction and synchrotron X-ray powder diffraction techniques. Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:3 Topics: Amidines; Cardiovascular Agents; Electrons; Isoxazoles; Microscopy, Electron; Platelet Glycoprotein GPIIb-IIIa Complex; Synchrotrons; X-Ray Diffraction	1999
Optimization and validation of chiral high-performance liquid chromatographic method for analysis of a fibrinogen (gpIIb/IIIa) receptor antagonist. Journal of chromatography. A, 1999, Jun-04, Volume: 844, Issue:1-2 Topics: Amidines; Chromatography, High Pressure Liquid; Fibrinolytic Agents; Isoxazoles; Orosomucoid; Platelet Glycoprotein GPIIb-IIIa Complex; Quality Control; Sensitivity and Specificity; Stereoisomerism	1999
Intravenous and oral antithrombotic efficacy of the novel platelet GPIIb/IIIa antagonist roxifiban (DMP754) and its free acid form, XV459. Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:10 Topics: Administration, Oral; Amidines; Amino Acids; Animals; Bleeding Time; Disease Models, Animal; Dogs; Electroshock; Female; Femoral Artery; Humans; Injections, Intravenous; Isoxazoles; Male; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis	1999
Roxifiban. DMP 754, MK 0853, XJ 754. Drugs in R&D, 1999, Volume: 1, Issue:5 Topics: Amidines; Animals; Dogs; Humans; In Vitro Techniques; Isoxazoles; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis	1999
Automated sample preparation of Roxifiban tablets: transfer of a manual method to an automated workstation. Journal of pharmaceutical and biomedical analysis, 2000, Volume: 21, Issue:6 Topics: Amidines; Automation; Chromatography, High Pressure Liquid; Drug Compounding; Fibrinolytic Agents; Isoxazoles; Placebos; Reproducibility of Results; Tablets	2000
Analysis of potassium counter ion and inorganic cation impurities in pharmaceutical drug substance by capillary electrophoresis with conductivity detection. Journal of pharmaceutical and biomedical analysis, 2000, Volume: 22, Issue:1 Topics: Amidines; Calibration; Cations; Creatinine; Crown Ethers; Drug Contamination; Electric Conductivity; Electrophoresis, Capillary; Etanidazole; Ethers, Cyclic; Indicators and Reagents; Isoxazoles; Losartan; Pharmaceutical Preparations; Potassium; Spectrophotometry, Atomic	2000
Comparative in vitro efficacy of different platelet glycoprotein IIb/IIIa antagonists on platelet-mediated clot strength induced by tissue factor with use of thromboelastography: differentiation among glycoprotein IIb/IIIa antagonists. Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:4 Topics: Abciximab; Alanine; Amidines; Antibodies, Monoclonal; Blood Coagulation; Blood Platelets; Elasticity; Fibrin; Humans; Immunoglobulin Fab Fragments; Isoxazoles; Nephelometry and Turbidimetry; Oxazoles; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Sulfonamides; Thrombelastography; Thromboplastin; Viscosity	2000
Differential antiplatelet efficacy for various GPIIb/IIIa antagonists: role of plasma calcium levels. Cardiovascular research, 2000, Volume: 47, Issue:4 Topics: Abciximab; Alanine; Amidines; Analysis of Variance; Antibodies, Monoclonal; Anticoagulants; Blood Platelets; Calcium; Citric Acid; Eptifibatide; Fibrinogen; Heparin; Humans; Immunoglobulin Fab Fragments; Iodine Radioisotopes; Isoxazoles; Peptides; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Pyrrolidines; Tirofiban; Tyrosine	2000
Crystalline versus amorphous content of lumaxistrade mark analog XP280 using X-ray and electron diffraction methods. Journal of pharmaceutical sciences, 2000, Volume: 89, Issue:10 Topics: Amidines; Cardiovascular Agents; Crystallization; Isoxazoles; Mesylates; Microscopy, Electron; X-Ray Diffraction	2000
Comparative efficacy of different low-molecular-weight heparins (LMWHs) and drug interactions with LMWH: implications for management of vascular disorders. Seminars in thrombosis and hemostasis, 2000, Volume: 26 Suppl 1 Topics: Amidines; Antifibrinolytic Agents; Blood Coagulation; Clot Retraction; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Heparin, Low-Molecular-Weight; Humans; Isoxazoles; Kinetics; Platelet Aggregation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombelastography; Tinzaparin; Vascular Diseases	2000
Synthesis of cis and trans isomers of an isoxazoline ring-hydroxylated metabolite of roxifiban, a platelet glycoprotein IIb/IIIa receptor antagonist. The Journal of organic chemistry, 2000, Nov-17, Volume: 65, Issue:23 Topics: Amidines; Animals; Dogs; Humans; Isoxazoles; Platelet Glycoprotein GPIIb-IIIa Complex; Rats	2000
Mass spectrometric and NMR characterization of metabolites of roxifiban, a potent and selective antagonist of the platelet glycoprotein IIb/IIIa receptor. Xenobiotica; the fate of foreign compounds in biological systems, 2000, Volume: 30, Issue:11 Topics: Amidines; Amino Acids; Animals; Cardiovascular Agents; Chromatography, High Pressure Liquid; Dogs; Feces; Gas Chromatography-Mass Spectrometry; Humans; Isoxazoles; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Thrombosis	2000
Platelet GPIIb/IIIa binding characteristics of small molecule RGD mimetic: distinct binding profile for Roxifiban. British journal of pharmacology, 2001, Volume: 133, Issue:3 Topics: Amidines; Binding, Competitive; Blood Platelets; Collagen; Fibrinogen; Fibrinolytic Agents; Humans; Inhibitory Concentration 50; Isoxazoles; Kinetics; Ligands; Microscopy, Confocal; Molecular Mimicry; Oligopeptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Structure-Activity Relationship; Thermodynamics	2001
Comparative efficacy between the glycoprotein IIb/IIIa antagonists roxifiban and orbofiban in inhibiting platelet responses in flow models of thrombosis. Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:4 Topics: Alanine; Amidines; Blood Platelets; Dose-Response Relationship, Drug; Fibrinolytic Agents; Humans; Isoxazoles; Models, Biological; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Thrombosis	2002
Evidence that thrombocytopenia observed in humans treated with orally bioavailable glycoprotein IIb/IIIa antagonists is immune mediated. Blood, 2002, May-15, Volume: 99, Issue:10 Topics: Administration, Oral; Amidines; Animals; Antibodies; Biological Availability; Clinical Trials, Phase II as Topic; Enzyme-Linked Immunosorbent Assay; Epitopes; Humans; Isoxazoles; Kinetics; Pan troglodytes; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Conformation; Sensitivity and Specificity; Thrombocytopenia	2002
Anti-platelet effects of GPIIb/IIIa and P-selectin antagonism, platelet activation, and binding to neutrophils. Journal of cardiovascular pharmacology, 2002, Volume: 40, Issue:2 Topics: Abciximab; Amidines; Analysis of Variance; Antibodies, Monoclonal; Cells, Cultured; Humans; Immunoglobulin Fab Fragments; Isoxazoles; Neutrophils; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Tirofiban; Tyrosine	2002
Solid-state carbon NMR characterization of the polymorphs of roxifiban. Journal of pharmaceutical and biomedical analysis, 2002, Aug-22, Volume: 30, Issue:1 Topics: Amidines; Calibration; Crystallization; Indicators and Reagents; Isoxazoles; Magnetic Resonance Spectroscopy; Platelet Glycoprotein GPIIb-IIIa Complex	2002
Effects of orally active glycoprotein IIb/IIIa antagonists on platelet CD40 ligand (CD154) expression and platelet-heteroaggregate formation. Thrombosis research, 2002, Apr-01, Volume: 106, Issue:1 Topics: Administration, Oral; Alanine; Amidines; CD40 Ligand; Cell Adhesion; Dose-Response Relationship, Drug; Humans; Isoxazoles; Leukocytes; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Proteins; Pyrrolidines; Receptors, Thrombin	2002
Polymorphism of roxifiban. Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:12 Topics: Amidines; Calorimetry; Chemistry, Pharmaceutical; Isoxazoles	2002
Comparative analysis of various platelet glycoprotein IIb/IIIa antagonists on shear-induced platelet activation and adhesion. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3 Topics: Abciximab; Alanine; Amidines; Analysis of Variance; Antibodies, Monoclonal; Anticoagulants; Aspirin; Cell Aggregation; Dose-Response Relationship, Drug; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Isoxazoles; Peptides; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Rheology; Shear Strength; Temperature; Tirofiban; Tyrosine	2002
A double antibody radioimmunoassay for the determination of XV459, the active hydrolysis metabolite of roxifiban, in human plasma. Journal of pharmaceutical and biomedical analysis, 2003, Jan-01, Volume: 30, Issue:5 Topics: Amidines; Amino Acids; Animals; Antibodies; Binding Sites; Humans; Isoxazoles; Linear Models; Rabbits; Radioimmunoassay	2003
New applications of electron diffraction in the pharmaceutical industry: polymorph determination by using a combination of electron diffraction and synchrotron X-ray powder diffraction techniques. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada, 2002, Volume: 8, Issue:2 Topics: Amidines; Drug Industry; Isoxazoles; Microscopy, Electron; Powder Diffraction; Powders; Synchrotrons; Technology, Pharmaceutical; X-Ray Diffraction	2002
Effects of glycoprotein IIb/IIIa antagonists on platelet activation: development of a transfer method to mimic peak to trough receptor occupancy. Thrombosis research, 2002, Sep-15, Volume: 107, Issue:6 Topics: Alanine; Amidines; Benzodiazepines; Blood Platelets; Humans; In Vitro Techniques; Isoxazoles; Oximes; P-Selectin; Piperidines; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Thrombosis	2002
Regulation of clot retraction by glycoprotein IIb/IIIa antagonists. Thrombosis research, 2002, Nov-01, Volume: 108, Issue:2-3 Topics: Abciximab; Alanine; Amidines; Antibodies, Monoclonal; Blood Platelets; Clot Retraction; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Isoxazoles; Phosphorylation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Sulfonamides; Tyrosine	2002
CD32-dependent platelet activation by a drug-dependent antibody to glycoprotein IIb/IIIa antagonists. Thrombosis and haemostasis, 2003, Volume: 89, Issue:3 Topics: Amidines; Animals; Antibodies, Monoclonal; Blood Platelets; Cysteine Endopeptidases; Humans; In Vitro Techniques; Isoxazoles; Mice; Neoplasm Proteins; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, IgG; Thrombocytopenia	2003
Simultaneous quantification of seven active metabolites of roxifiban in human plasma by LC/MS/MS in the presence of an interfering displacer at millimolar concentrations. Journal of pharmaceutical and biomedical analysis, 2003, Apr-01, Volume: 31, Issue:5 Topics: Amidines; Calibration; Chromatography, High Pressure Liquid; Humans; Isoxazoles; Mass Spectrometry; Mesylates; Peptides, Cyclic; Platelet Glycoprotein GPIIb-IIIa Complex; Reproducibility of Results	2003
AlphaIIbbeta3 priming and clustering by orally active and intravenous integrin antagonists. Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:3 Topics: Administration, Oral; Alanine; Amidines; Binding, Competitive; Blood Platelets; Dimerization; Dose-Response Relationship, Drug; Eptifibatide; Female; Fibrinogen; Humans; In Vitro Techniques; Injections, Intravenous; Intercellular Signaling Peptides and Proteins; Isoxazoles; Kinetics; Male; Models, Molecular; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Conformation; Pyrrolidines; Reference Values; Structure-Activity Relationship; Tirofiban; Tyrosine	2007
Validation and implementation of drug-dependent antibody assays in clinical trials for safety monitoring of patients dosed with roxifiban, an orally bioavailable glycoprotein IIb/IIIa antagonist. Journal of pharmaceutical and biomedical analysis, 2007, Aug-15, Volume: 44, Issue:4 Topics: Amidines; Antibodies; Biological Availability; Clinical Trials as Topic; Drug Storage; Enzyme-Linked Immunosorbent Assay; Freezing; Humans; Immunoassay; Indicators and Reagents; Isoxazoles; Platelet Glycoprotein GPIIb-IIIa Complex; Quality Control; Recombinant Proteins; Reproducibility of Results	2007
Integrin priming dynamics: mechanisms of integrin antagonist-promoted alphaIIbbeta3:PAC-1 molecular recognition. Biochemistry, 2009, Sep-08, Volume: 48, Issue:35 Topics: Amidines; Dual Specificity Phosphatase 2; Eptifibatide; Integrins; Intercellular Signaling Peptides and Proteins; Isoxazoles; Models, Molecular; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Thermodynamics; Tirofiban; Tyrosine	2009
Enantio- and Chemoselective Intramolecular Iridium-Catalyzed Organic letters, 2021, 04-02, Volume: 23, Issue:7 Topics: Amidines; Catalysis; Iridium; Isoxazoles; Molecular Structure; Oximes; Propanols; Stereoisomerism	2021