isoxazoles has been researched along with risperidone in 433 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (1.85) | 18.7374 |
| 1990's | 192 (44.34) | 18.2507 |
| 2000's | 112 (25.87) | 29.6817 |
| 2010's | 118 (27.25) | 24.3611 |
| 2020's | 3 (0.69) | 2.80 |
| Authors | Studies |
|---|---|
| Lindström, E; von Knorring, L | 4 |
| Heykants, J; Lorreyne, W; Van Rompaey, F; Woestenborghs, R | 1 |
| Awouters, FH; Janssen, PA; Meert, TF; Megens, AA; Niemegeers, CJ; Schellekens, KH | 1 |
| Awouters, FH; Megens, AA; Niemegeers, CJ | 2 |
| Gommeren, W; Janssen, PA; Janssen, PM; Leysen, JE; Pauwels, PJ; Wynants, J | 1 |
| Bollen, J; Claus, A; De Cuyper, H; Eneman, M; Heylen, S; Malfroid, M; Peuskens, J | 1 |
| Baert, AL; Bollen, J; Claus, A; De Cuyper, H; Eneman, M; Heylen, S; Malfroid, M; Peuskens, J; Van Ongeval, C; Wilms, G | 1 |
| Gelders, YG; Heylen, SL | 1 |
| Müller-Spahn, F | 1 |
| Marder, SR | 1 |
| Bowden, CR; De Coster, R; Heykants, J; Voina, SJ; Woestenborghs, R | 1 |
| Borison, RL; Diamond, BI; Meibach, RC; Pathiraja, AP | 1 |
| Benkert, O; Hillert, A; Maier, W; Wetzel, H | 1 |
| Awouters, F; Janssen, PA; Megens, AA; Niemegeers, CJ | 1 |
| Gelders, YG; Heylen, SL; Janssen, PA; Reyntjens, AJ; Vanden Bussche, G | 1 |
| Bogdanov, MB; Gaĭnetdinov, RR; Kudrin, VS; Medvedev, OS; Val'dman, AV | 1 |
| Gerlach, J | 1 |
| Kissling, W; Möller, HJ; Pelzer, E; Riehl, T; Wernicke, T | 1 |
| Awouters, F; Janssen, PA; Meert, TF; Megens, AA; Niemegeers, CJ; Schellekens, KH | 1 |
| de Chaffoy de Courcelles, D; Eens, A; Gommeren, W; Janssen, PA; Leysen, JE; Stoof, JC | 1 |
| de Haes, P; Janssen, PA; Meert, TF | 1 |
| Burton, P; Gelders, Y; Heylen, S; Mesotten, F; Pietquin, M; Suy, E | 1 |
| Gelders, YG | 1 |
| de Bruyckere, K; Janssen, PF; Leysen, JE; Schotte, A | 1 |
| Dugovic, C; Janssen, PA; Wauquier, A | 1 |
| Kerwin, R | 1 |
| Jeffries, JJ | 1 |
| MacEwan, GW | 1 |
| Ereshefsky, L; Lacombe, S | 1 |
| Arnott, W; Chouinard, G | 1 |
| Remington, GJ | 2 |
| Kane, JM | 4 |
| Busatto, GF; Costa, DC; Ell, PJ; Kerwin, RW; Pilowsky, LS; Verhoeff, NP | 2 |
| Livingston, MG | 1 |
| Ciccocioppo, R; Massi, M; Panocka, I; Pompei, P | 1 |
| Fensbo, C; Høyberg, OJ; Lingjaerde, O; Remvig, J; Salvesen, I; Sloth-Nielsen, M | 1 |
| Heinrich, K; Hruschka, H; Kinzler, E; Klieser, E; Lehmann, E | 1 |
| Janssen, PF; Leysen, JE; Megens, AA; Schotte, A | 1 |
| Czyrak, A; Frankiewicz, T; Maj, J; Rogóz, Z; Skuza, G | 1 |
| Aghajanian, GK; Gellman, RL | 1 |
| Kerwin, RW | 1 |
| Alessandria, A; Bonifati, V; Giustini, P; Meco, G | 1 |
| Marder, SR; Meibach, RC | 1 |
| Awouters, FH; Janssen, PA | 1 |
| Kido, H; Mori, H; Sakamoto, H; Shiba, K; Sumiyoshi, T; Suzuki, K; Urasaki, K; Yamaguchi, N; Yokogawa, K | 1 |
| Davidson, JE; Mosqueda, RA | 1 |
| Edwards, JG | 1 |
| Dalby, JT; Dickson, R; Williams, R | 1 |
| Emes, CE; Millson, RC | 1 |
| Land, W; Salzman, C | 1 |
| Littrell, K; Schultz, RE | 1 |
| Jahnová, E | 1 |
| Dwight, MM; Keck, PE; McElroy, SL; Stanton, SP; Strakowski, SM | 1 |
| Mok, H; Yatham, LN | 1 |
| Heykants, J; Huang, ML; Mannens, G; Meuldermans, W; Snoeck, E; Van Beijsterveldt, L; Van Peer, A; Woestenborghs, R | 1 |
| McEvoy, JP | 1 |
| Schooler, NR | 1 |
| Owens, DG | 1 |
| Janssen, PM; Leysen, JE; Megens, AA; Schotte, A | 1 |
| Ford, B; Greene, P; Lynch, T | 1 |
| Goodman, WK; McDougle, CJ; Price, LH | 1 |
| Sussman, N | 1 |
| Catalan, J; Singh, AN | 1 |
| Webster, P; Wijeratne, C | 1 |
| Honer, WG; Kopala, L | 1 |
| Goldberg, TE; Weinberger, DR | 1 |
| Cozza, SJ; Edison, DL | 1 |
| Aschauer, H; Kasper, S; Stamenkovic, M | 1 |
| Finlayson, R; Jones, BD; Labelle, A; Purdon, SE | 1 |
| Jones, BD; Labelle, A; Lit, W; Purdon, SE | 1 |
| Fitton, A; Grant, S | 1 |
| Eilers, R | 1 |
| Elomaa, E; Raitasuo, V; Vataja, R | 1 |
| Brammer, M; Bullmore, E; David, A; Howard, R; Mellers, J; Williams, S; Woodruff, P | 1 |
| Bennett, JA; Keck, PE; Wallhausser, LJ | 1 |
| Bennie, EH | 1 |
| Adams, M; Remington, G | 1 |
| Brocco, M; Millan, MJ; Schreiber, R | 1 |
| Eriksson, B; Eriksson, L; Farde, L; Halldin, C; Nyberg, S | 1 |
| Janssen, PM; Leysen, JE; Luyten, WH; Megens, AA; Schotte, A | 1 |
| Borison, RL; Diamond, B; Meibach, RC; Pathiraja, A | 1 |
| Post, L | 1 |
| Bruggeman, R; van der Linden, C; van Woerkom, TC | 1 |
| Geerts, RJ; Heykants, JJ; Leysen, JE; Megens, AA; Meuldermans, WE; van Beijsterveldt, LE; Van den Eynde, HM | 1 |
| Awouters, FH; Dugovic, C; Leysen, JE; Meert, TF; Megens, AA; Niemegeers, CJ; Schotte, A | 1 |
| Beaudry, P; Bélanger, MC; Chouinard, G; Miller, R; Roy, JY; Turnier, L; Vainer, JL | 1 |
| Perrault, G; Sanger, DJ | 1 |
| Auchus, AP; Freeman, A; Green, RC | 1 |
| Heykants, J; Mannens, G; Meuldermans, W; Snoeck, E | 1 |
| Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Yamada, K | 1 |
| Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Ogita, K; Yamada, K; Yoneda, Y | 1 |
| Keegan, D | 1 |
| Villeneuve, A | 1 |
| Sigmundson, HK | 1 |
| Holt, L; O'Croinin, F; Zibin, T | 1 |
| Lee, MA; Meltzer, HY; Ranjan, R | 1 |
| Black, DW; Gupta, S; Smith, DA | 1 |
| Honer, WG; Kopala, LC | 1 |
| Clarke, DE; Yaeger, SF | 1 |
| Bryois, C | 1 |
| Ericsson, B; Farde, L; Halldin, C; Nakashima, Y; Nyberg, S; Oxenstierna, G | 1 |
| Borison, RL | 1 |
| Chouinard, G | 1 |
| Heinrich, K; Kinzler, E; Klieser, E; Lehmann, E; Wurthmann, C | 1 |
| Tavares, AR | 1 |
| DeVane, CL | 1 |
| Love, RC | 1 |
| Perry, PJ | 1 |
| Curtis, VA; Kerwin, RW | 1 |
| Breier, A | 1 |
| Sternlicht, HC; Wells, SR | 1 |
| Pickar, D | 1 |
| Borison, RL; Chouinard, G; Möller, HJ; Müller, H; Schooler, NR | 1 |
| McEvoy, JP; Price, WA; Swanson, CL | 1 |
| Byerly, MJ; Evans, DL; Greer, RA | 1 |
| Silva, JA; Smith, EA; Tekell, JL | 1 |
| Giakas, WJ | 1 |
| Zimbroff, DL | 1 |
| Dalby, JT; Dickson, RA; Edwards, AL; Williams, R | 1 |
| Pelonero, AL | 1 |
| Allen, RL; D'Ath, PJ; Katona, CL; Walker, Z | 1 |
| Price, PL | 1 |
| Möller, HJ | 1 |
| Lindenmayer, JP | 1 |
| Azorin, JM | 1 |
| Aubert, AC; Baumann, P; Bondolfi, G; Meylan, C | 1 |
| Farde, L; Hall, H; Halldin, C; Nyberg, S; Sedvall, G | 1 |
| Shulman, LM; Singer, C; Weiner, WJ | 1 |
| He, H; Richardson, JS | 1 |
| McCarthy, RH; Terkelsen, KG | 1 |
| Huttunen, MO; Larmo, I; Nyholm, R; Piepponen, T; Raitasuo, V; Rantanen, H | 1 |
| Allen, M; Field, K; Ganguli, R; Reddy, R; Tanner, TB | 1 |
| Dave, M | 1 |
| Boland, RJ; Richards, C; Singer, S | 1 |
| Alderman, CP; Fraser, CD | 1 |
| Davis, YB; Jeanblanc, W | 1 |
| Cott, J; Lieberman, JA; Matthews, S; Shore, D | 1 |
| Borison, RL; Brown, TM; Radford, JM | 1 |
| Kirisci, L; Musser, WS | 1 |
| Goss, JB | 1 |
| Houle, S; Kapur, S; Remington, G; Wilson, AA; Zipursky, RB | 1 |
| Fras, I; Major, LF | 1 |
| Jerkovich, GS; Lacey, RL; Preskorn, SH | 1 |
| Devane, CL; Risch, SC; Tyson, SC | 1 |
| Ballard, CG; Harrison, RW; McKeith, IG | 1 |
| Benvenga, MJ; Leander, JD | 1 |
| Cardoni, AA | 1 |
| Peuskens, J | 1 |
| Jacobsen, FM | 1 |
| Goodnick, PJ | 1 |
| Kane, JM; McGlashan, TH | 1 |
| Dahl, ML; Halldin, C; Nyberg, S | 1 |
| Conway, PG; Corbett, R; Cornfeldt, M; Rush, DK; Strupczewski, JT; Szewczak, MR; Wilmot, CA | 1 |
| Buttiëns, M; Dierick, G; Geutjens, J; Heylen, S; Sieben, G; Thiry, P; Vanden Borre, R; Vermote, R | 1 |
| Addington, D; Arnott, W; Beauclair, L; Bloom, D; Chouinard, G; Jones, B; Labelle, A; MacEwan, GW; Remington, G | 1 |
| Massi, M; Panocka, I; Pompei, P | 1 |
| Koyama, T; Kusumi, I; Matsubara, R; Matsubara, S; Yamashita, I | 1 |
| Remr, J | 1 |
| Jahnová, E; Keleová, A; Nyulassy, S | 1 |
| Conway, PC; Corbett, R; Dunn, RW; Hartman, H; Helsley, GC; Kerman, LL; Strupczewski, JT; Woods, AT | 1 |
| Edouard, S; Le Moing, JP; Levron, JC | 1 |
| Hayakawa, H; Kawai, K; Kikumoto, O; Motohashi, N; Okamoto, Y; Yamawaki, S; Yokota, N | 1 |
| Matsubara, R | 1 |
| Menkes, DB | 1 |
| Aravagiri, M; Marder, SR; Midha, KK; Van Putten, T | 1 |
| Assié, MB; Koek, W; Sleight, AJ | 1 |
| De Coster, R; Heykants, J; Huang, ML; Jansen, AA; Jonkman, JH; Van Peer, A; Visscher, HW; Woestenborghs, R; Zylicz, Z | 1 |
| Czyrak, A; Jaros, T; Maj, J; Moryl, E | 1 |
| Kang, DY; Kim, CE; Min, SK; Rhee, CS | 1 |
| Bigg, DC; Koek, W; Sleight, AJ | 1 |
| Czobor, P; Volavka, J | 1 |
| Cesková, E; Svestka, J | 1 |
| Brenner, C; Brown, K; Hamburg, EL; Leffler, S; Levy, H | 1 |
| Hoffman, DW; Price, MC | 1 |
| Linnet, K; Olesen, OV | 1 |
| Aravagiri, M; Marder, SR; Wirshing, D; Wirshing, WC | 1 |
| Bruun, T; Licht, RW; Linnet, K; Olesen, OV; Thomsen, E; Viftrup, JE | 1 |
| Aravagiri, M; Marder, SR; Yuwiler, A | 1 |
| Baker, GB; Bourin, M; Fang, J | 1 |
| Albano, D; Amchin, J; Klockowski, PM; Taylor, KP; Zarycranski, W | 1 |
| Cho, MJ; Jang, IJ; Kwon, JS; Lee, DY; Lee, KU; Shin, SG; Woo, JI | 1 |
| Bork, JA; de Leon, J; Rogers, T; Wedlund, PJ | 1 |
| Saria, A; Schatz, DS | 1 |
| Avenoso, A; Dahl, ML; Facciolà, G; Johansson, I; Scordo, MG; Spina, E | 1 |
| Doorschot, CH; Loonen, AJ; Oostelbos, MC; Sitsen, JM | 1 |
| Furukori, H; Kaneko, S; Nagasaki, T; Ohkubo, T; Sugawara, K; Yasui, N | 1 |
| Hackett, LP; Hill, RC; Ilett, KF; McIvor, RJ; Wojnar-Horton, RE | 1 |
| Cui, D; Kamel, A; Miceli, JJ; Prakash, C; Tweedie, D; Whalen, RD | 1 |
| Chang, WH; Chiu, WC; Chou, JC; Lane, HY; Su, MH; Wu, ST | 1 |
| Aravagiri, M; Marder, SR | 2 |
| Nakamura, J; Terao, T; Ueda, N; Yoshimura, R | 1 |
| Avenoso, A; Facciolà, G; Giacobello, T; Madia, AG; Perucca, E; Salemi, M; Scordo, MG; Spina, E | 1 |
| Aamo, T; Güzey, C; Spigset, O | 1 |
| Avenoso, A; Facciolà, G; Salemi, M; Spina, E | 1 |
| Ancione, M; Avenoso, A; Facciolà, G; Madia, AG; Perucca, E; Salemi, M; Scordo, MG; Spina, E | 1 |
| Ancione, M; Avenoso, A; Facciolà, G; Madia, A; Scordo, MG; Spina, E | 1 |
| Nakamura, J; Ueda, N; Yoshimura, R | 1 |
| Albert, MJ; Baldessarini, RJ; Centorrino, F; Kelleher, JP | 1 |
| Déridet, E; Moore, N; Titier, K | 1 |
| Abouelfath, A; Cardone, E; Déridet, E; Moore, N; Titier, K | 1 |
| Kastango, KB; Kirshner, MA; Maxwell, RA; Mulsant, BH; Pollock, BG; Rosen, J; Sweet, RA | 1 |
| Fukuda, M; Iga, T; Nakashima, Y; Ohno, Y; Sato, H; Sawada, Y; Takayanagi, R; Tsuchiya, F; Yamada, Y | 1 |
| Thiam, S; Valle, BC; Warner, IM; Zhu, X | 1 |
| Berecz, R; Cáceres, M; de la Garza, CS; Dorado, P; Gutiérrez, JR; LLerena, A; Norberto, MJ | 1 |
| Huang, F; Janssens, L; Lasseter, KC; Lau, H; Verhaeghe, T; Zhao, Q | 1 |
| de Jong, J; de Vries, R; Hooijschuur, EW; Remmerie, BM; Schothuis, AM; Sips, LL; van de Merbel, NC | 1 |
| Berecz, R; de la Rubia, A; Degrell, I; Dorado, P; Gómez, J; Kellermann, M; LLerena, A | 1 |
| Xiao, H; Yang, J; Zhang, S; Zhang, X | 1 |
| Kalkman, HO; Loetscher, E | 1 |
| De Vries, R; Iga, T; Kaneko, S; Kondo, T; Kubota, T; Mihara, K; Takarada, Y; Tateishi, T; Yasui-Furukori, N | 1 |
| de Vries, R; Iga, T; Ishida, M; Kaneko, S; Kondo, T; Kubota, T; Mihara, K; Ono, S; Suzuki, A; Takarada, Y; Yasui-Furukori, N | 1 |
| Ko, G; Lasseter, KC; Lechat, P; Mannaert, E; Remmerie, BM; van Schaick, EA | 1 |
| Aravagiri, M; Gitlin, MJ; Marder, SR; Nuechterlein, KH | 1 |
| Begg, EJ; Gardiner, SJ; Hackett, LP; Ilett, KF; Kristensen, JH; Vaddadi, KS | 1 |
| Aman, M; Flarakos, J; Gerber, N; Luo, W; Svinarov, D; Vouros, P | 1 |
| Chang, JW; Chen, PS; Liao, YC; Su, SF; Yang, YK; Yeh, TL | 1 |
| De Vries, R; Kaneko, S; Kondo, T; Mihara, K; Nakagami, T; Suzuki, A; Takahata, T; Tateishi, T; Yasui-Furukori, N | 1 |
| Calamoneri, F; D'Arrigo, C; Gagliano, A; Germanò, E; Impallomeni, C; Pustorino, G; Spina, E | 1 |
| Ancione, M; D'Arrigo, C; Madia, A; Migliardi, G; Morgante, L; Spina, E; Zoccali, R | 1 |
| Berecz, R; de la Rubia, A; Dorado, P; Llerena, A | 1 |
| De Clerck, F; Eerdekens, M; Greenspan, A; Mannaert, E; Somers, Y | 1 |
| Foltz, RL; Huang, W; Laycock, JD; Moody, DE | 1 |
| Möller, HJ; Müller, N; Müller-Arends, A; Riedel, M; Schwarz, MJ; Spellmann, I; Strassnig, M; Weber, K; Zach, J | 1 |
| Castberg, I; Spigset, O | 1 |
| DeVane, CL; Donovan, JL; Markowitz, JS; Ruan, Y; Taylor, RM; Wang, JS | 1 |
| Björner, A; Eerdekens, M; Eriksson, B; Gefvert, O; Helldin, L; Mannaert, E; Nyberg, S; Persson, P; Remmerie, B | 1 |
| Aichhorn, W; Stuppaeck, C; Whitworth, AB | 1 |
| Goto, M; Kaji, K; Kakihara, S; Matsumoto, C; Nakamura, J; Ohmori, O; Shinkai, K; Ueda, N; Yamada, Y; Yoshimura, R | 1 |
| Baselmans, P; Bosker, F; Bruggeman, R; Castelein, S; Knegtering, R; van den Bosch, RJ | 1 |
| Aichhorn, W; Geretsegger, C; Kemmler, G; Marksteiner, J; Stelzig-Schoeler, R; Stuppaeck, C; Walch, T; Weiss, U; Zernig, G | 1 |
| Kaneo, S; Nakagami, T; Saito, M; Tateishi, T; Yasui-Furukori, N | 1 |
| Kapur, B; Koren, G; Railton, CJ | 1 |
| Furukori, H; Kaneko, S; Nakagami, T; Saito, M; Yasui-Furukori, N | 1 |
| Chan, YH; Chong, SA; Tan, CH; Verma, SK | 1 |
| Byun, WT; Cho, HK; Jung, IG; Jung, SM; Kim, KA; Park, JY; Park, PW | 1 |
| Ariën, A; Brewster, M; Mathot, F; Préat, V; van Beijsterveldt, L | 1 |
| Deng, CY; Li, HD; Li, WB; Li, X; Lin, QX; Lin, SG; Peng, HY; Su, FL; Wang, CY; Wang, F; Yang, M; Yu, XY; Zhou, ZL; Zhu, RH | 1 |
| Kapur, S; Labelle, A; Mamo, D; Mann, S; Mannaert, E; Reiss, J; Remington, G; Shammi, C | 1 |
| Bastianetto, S; Danik, M; Mennicken, F; Quirion, R; Williams, S | 1 |
| Hendset, M; Nesvåg, R; Refsum, H; Tanum, L | 1 |
| Bhatt, J; Singh, S; Subbaiah, G | 1 |
| Didriksen, M; Kreilgaard, M; Olsen, CK | 1 |
| DeVane, CL; Donovan, JL; Markowitz, JS; Wang, JS; Zhu, HJ | 1 |
| Cho, HY; Lee, YB | 1 |
| DeVane, CL; Donovan, JL; Gibson, BB; Markowitz, JS; Wang, JS; Zhu, HJ | 1 |
| Duan, S; Feng, G; Gao, R; He, L; Li, H; Meng, J; Qin, S; Xing, Q; Xu, M; Zhang, A | 1 |
| Melkersson, KI | 1 |
| Ludwig, EA; Piotrovsky, V; Vermeulen, A | 1 |
| Buitelaar, JK; Hermans, MH; Hoekstra, PJ; Lahuis, BE; Minderaa, RB; Scahill, L; Troost, PW; van Engeland, H | 1 |
| Nakamura, J; Shinkai, K; Ueda, N; Yoshimura, R | 1 |
| Cabovska, B; Cox, SL; Vinks, AA | 1 |
| Hori, H; Kakihara, S; Mitoma, M; Nakamura, J; Nakano, Y; Ohta, M; Shinkai, K; Shinkai, T; Sugita, A; Ueda, N; Umene, W; Yoshimura, R | 1 |
| D'Hoore, P; Kushner, S; Mannaert, E; Remmerie, B; Thyssen, A | 1 |
| Blier, P; Dremencov, E; El Mansari, M | 1 |
| Diaz, FJ; Leon, Jd; Orrego, ML; Pan, RM; Susce, MT; Wedlund, PJ | 1 |
| Piniella, PM; Relleke, M; van Os, S | 1 |
| Canuso, CM; Kujawa, M; Mahmoud, R; Pandina, GJ; Youssef, E | 1 |
| Azarzar, D; Bartélémy, C; Bonte, JP; Chaminade, P; Danel, C; Odou, P; Vaccher, C | 1 |
| Azarzar, D; Barthélémy, C; Bonte, JP; Danel, C; Odou, P; Robert, H; Vaccher, C | 1 |
| Ding, JJ; Jiao, Z; Shi, XJ; Yu, YQ | 1 |
| Du, J; Fang, C; Feng, GY; Gu, NF; He, L; Li, XW; Qin, SY; Wang, L; Xing, QH; Yu, L; Zhang, AP | 1 |
| Bartlett, MG; Terry, AV; Zhang, G | 1 |
| Aman, MG; Lindsay, RL; Malone, K; Mannaert, E; Masty, J; Ramadan, Y; Remmerie, B; Vinks, AA | 1 |
| Bharathi, Ch; Chary, DK; Dandala, R; Handa, VK; Kumar, MS; Naidu, A; Shankar, R | 1 |
| Crocq, MA; Duval, F; Garcia Duarte, F; Guillon, MS; Mokrani, MC | 1 |
| Awouters, FH; Lewi, PJ | 1 |
| Kim, KA; Kim, KB; Lee, HJ; Liu, KH; Park, JY; Park, PW; Shin, JG | 1 |
| Henken, S; Hiemke, C; Kirschbaum, KM; Schmitt, U | 1 |
| Dopheide, JA | 1 |
| Deyo, Z; Dolder, C; Nelson, M | 1 |
| Nussbaum, A; Stroup, TS | 1 |
| Bossie, CA; Canuso, CM; Schreiner, A; Simpson, GM; Turkoz, I; Youssef, EA | 1 |
| Boom, S; De Meulder, M; de Vries, R; Hooijschuur, EW; Remmerie, BM; Sips, LL; Timmerman, PM; van de Merbel, NC | 1 |
| Darby, JK; Herbert, J; Pasta, DJ; Wilson, MG | 1 |
| Dahl, ML; Gunes, A; Scordo, MG; Spina, E | 1 |
| Eliasson, E; Mannheimer, B; Pettersson, H; von Bahr, C | 1 |
| Clement, HW; Heiser, P; Hemmeter, UM; Krieg, JC; Schmidt, AJ; Schulz, E; Vedder, H | 1 |
| Lublin, HK; Maknyte, K | 1 |
| Aravagiri, M; Bies, RR; Coley, K; Feng, Y; Kirshner, M; Marder, S; Miller, D; Pollock, BG; Schneider, L | 1 |
| Klein, MT; Knight, JA; Smith, C; Teitler, M; Toohey, N | 2 |
| Chen, CC; Chiu, CC; Huang, MC; Pan, CH; Peng, PW; Tsai, CJ | 1 |
| Azaroual, N; Brunel, A; Danel, C; Lannoy, D; Odou, P; Vaccher, C; Vermeersch, G | 1 |
| Friberg, LE; Karlsson, MO; Petersson, KJ; Vermeulen, AM | 1 |
| Cabré, F; Cánovas, M; Cebrecos, J; Delgadillo, J; Pelagio, P; Riba, N; Torres, F | 1 |
| Graff-Guerrero, A; Kapur, S; Mamo, DC; Mulsant, BH; Pollock, BG; Uchida, H | 1 |
| Marchese, G; Pani, L | 1 |
| Charles, B; Dean, AJ; Jones, T; McDermott, BM; Norris, R; Van Breda, K | 1 |
| Kumar, R; Sachdev, PS | 1 |
| Chino, B; Kosaki, K; Mizuno, M; Sakuma, K; Sato, Y; Takao, T; Takebayashi, T; Yagihashi, T | 1 |
| Che, R; Du, J; Feng, G; Gu, N; He, L; Li, X; Lin, Z; Wang, L; Xing, Q; Xuan, J; Yu, L; Zhang, A | 1 |
| Cho, HK; Han, C; Jung, BJ; Jung, SM; Kang, RH; Kim, KA; Kim, SH; Kim, YK; Lee, DK; Lee, MS; Park, JY | 1 |
| Chen, CH; Chiu, CC; Huang, MC; Lai, YC; Pan, CH; Tsai, CJ | 1 |
| Furukori, H; Kaneko, S; Kondo, T; Nakagami, T; Saito, M; Suzuki, A; Yasui-Furukori, N | 1 |
| Klein, MT; Knight, J; Smith, C; Teitler, M; Toohey, N | 1 |
| De Rossi, P; Girardi, P; Kotzalidis, GD; Lionetto, L; Lostia, AM; Mazzarini, L; Pacchiarotti, I; Sani, G; Sanna, L; Simmaco, M; Tatarelli, R | 1 |
| Grabnar, I; Locatelli, I; Mrhar, A | 1 |
| Mühe, A; Neels, H; Schneider, S; Sibille, E; Wennig, R; Yegles, M | 1 |
| Casu, G; Deriu, A; Lazzari, P; Marchese, G; Pani, L; Peddio, G; Pira, M; Pisu, C; Pittau, B; Portesani, F; Spada, GP | 1 |
| Berwaerts, J; Boom, S; Cleton, A; Eerdekens, M; Janssens, L; Kramer, M; Remmerie, B; Rossenu, S; Talluri, K | 1 |
| Arakawa, R; Ito, H; Kodaka, F; Miyoshi, M; Okumura, M; Otsuka, T; Suhara, T; Takahashi, H; Takano, H | 1 |
| Hendset, M; Hermann, M; Molden, E; Refsum, H | 1 |
| Elliott, ES; Nelson, LA; Purvis, TL; Sommi, RW | 1 |
| Gründer, G; Orfanos, S; Paulzen, M | 1 |
| Alphs, L; Awad, AG; Canuso, CM; Damaraju, CV; Grinspan, A; Kalali, A; Merriman, U | 1 |
| Cui, YM; Duan, JL; Xiang, Q; Zhao, X; Zhou, Y | 1 |
| Burger, R; Fegert, J; Gerlach, M; Klampfl, K; Mehler-Wex, C; Pfuhlmann, B; Preuss, A; Rothenhöfer, S; Taurines, R; Wewetzer, Ch | 1 |
| Bader, W; Gründer, G; Haen, E; Hiemke, C; Nazirizadeh, Y; Paulzen, M; Pfuhlmann, B; Schwarz, M; Vogel, F; Zernig, G | 1 |
| Baldi, ML; Cerveri, G; De Gaspari, IF; Mauri, MC; Mencacci, C; Papa, P; Rolandi, ML; Volonteri, LS | 1 |
| Božina, N; Jakovljević, M; Jovanović, N; Lovrić, M; Medved, V; Peleš, AM | 1 |
| Fukui, N; Inoue, Y; Ono, S; Someya, T; Sugai, T; Suzuki, Y; Tsuneyama, N; Watanabe, J | 1 |
| Li, Y; Meng, Q; Su, Z; Sui, C; Sun, F; Teng, L; Yuan, L; Zhang, C | 1 |
| Hopkins, T; Nasrallah, HA; Pixley, SK | 1 |
| D'Souza, DC; Kane, JM; Keefe, RS; Patkar, AA; Tiller, JM; Yang, R; Youakim, JM | 1 |
| Atallah, AN; Melnik, T; Puga, ME; Soares, BG | 1 |
| Alphs, L; Gopal, S; Karcher, K; Kent, J; Kushner, S; Nuamah, I; Singh, J; Sliwa, JK | 1 |
| Bourcier, E; Brovedani, S; Lancelin, F; Le Masson, V; Lemeille, Y; Paubel, P; Piketty, ML | 1 |
| Gassmann-Mayer, C; Gopal, S; Hough, D; Lane, R; Pandina, G; Remmerie, B; Simpson, G | 1 |
| Anyama, NG; Bies, RR; Lieberman, JA; Marder, SR; Pollock, BG; Schneider, LS; Wessels, AM | 1 |
| Belotto, KC; Ferreira, AS; Gattaz, WF; Raposo, NR | 1 |
| Boncompagni, G; Lateana, D; Mandrioli, R; Mercolini, L; Raggi, MA | 1 |
| Boonleang, J; Mahatthanatrakul, W; Pipatrattanaseree, W; Tanthana, C | 1 |
| Bossie, CA; Canuso, CM; Lindenmayer, JP; Schooler, N; Turkoz, I | 1 |
| Gu, N; Li, H; Ning, X; Rui, Q; Xu, H | 1 |
| Alves, I; Nuss, P; Salgado, GF; Staneva, G; Tessier, C | 1 |
| Dumontet, J; Ensom, MH; Seto, K | 1 |
| Ahlbrand, R; Bronson, SL; Horn, P; McNamara, RK; Richtand, NM; Stanford, K | 1 |
| Cho, HY; Kang, HA; Lee, IK; Lee, SN; Lee, YB; Yoo, HD | 1 |
| Cole-Strauss, A; Jandacek, R; Lipton, JW; McNamara, RK; Rider, T; Tso, P | 1 |
| Calarge, CA; Miller, del D | 1 |
| Boonleang, J; Mahatthanatrakul, W; Pipatrattanaseree, W; Ridtitid, W; Rujimamahasan, N; Sriwiriyajan, S; Wongnawa, M | 1 |
| Andel, R; Becker, MA; Boaz, TL; Chandler, K; Desmarais, SL; Howe, A; Van Dorn, RA | 1 |
| Cai, HL; Li, HD; Li, LF; Zhang, J; Zhu, RH | 1 |
| Ahlbrand, R; Bronson, SL; Gudelsky, G; Kern, JR; Richtand, NM; Roenker, NL; Waterman, H | 1 |
| Alphs, L; Bossie, CA; Ma, YW; Sliwa, JK | 1 |
| Eerdekens, M; Fleischhacker, WW; Gassmann-Mayer, C; Gopal, S; Hough, D; Lane, R; Lim, P; Remmerie, B | 1 |
| Conley, RR; Fijal, BA; Hoffmann, VP; Houston, JP; Kinon, BJ; Stauffer, VL; Witte, MM; Zhao, F | 1 |
| Fujii, A; Kaneko, S; Nakagami, T; Saito, M; Sugawara, N; Tsuchimine, S; Yasui-Furukori, N | 1 |
| Bernardo, M; Gassó, P; Lafuente, A; Mas, S; Molina, O; Parellada, E | 1 |
| Albuquerque, NC; Borges, KB; Calixto, LA; de Gaitani, CM; de Jesus, LI; de Oliveira, AR; Furtado, NA; Pupo, MT; Simões, RA | 1 |
| Liang, CS; Yang, FW | 1 |
| Fukui, N; Inoue, Y; Ono, S; Saito, M; Someya, T; Sugai, T; Suzuki, Y; Tsuneyama, N; Watanabe, J | 2 |
| Citrome, L; Hochfeld, M; Meng, X; Stahl, SM | 1 |
| DiCrescento, S; Perry, R; Wolberg, J | 1 |
| Mori, T | 1 |
| Howell, LL; Muly, EC; Ritchie, J; Votaw, JR | 1 |
| Lane, HY; Teng, PR | 1 |
| Singh, D; Williams, O | 1 |
| Bies, RR; Mamo, DC; Mimura, M; Pollock, BG; Suzuki, T; Tsunoda, K; Uchida, H; Watanabe, K | 1 |
| Danhof, M; de Greef, R; Grimwood, S; Groothuis, GM; Johnson, M; Kozielska, M; Li, C; Pilla Reddy, V; Proost, JH; Vermeulen, A | 1 |
| Knoepflmacher, D; Shapley, L; Turner, EH | 1 |
| Martin, M; McGuire, A; Mehnert, A; Nicholl, D; Pudas, H | 1 |
| Chung, TS; Lung, FW | 1 |
| Bowskill, SV; Fisher, DS; Flanagan, RJ; Handley, SA; Patel, MX | 1 |
| Chung, YC; Kim, MG; Oh, KY; Park, MS; Park, TW; Yang, JC; Yoon, KS | 1 |
| Cho, HY; Lee, SN; Lee, YB; Yoo, HD; Yoon, H | 1 |
| Citrome, L | 1 |
| Haga, T; Hashizume, T; Inoue, T; Katsumata, T; Ogawa, Y; Osada, K; Sogame, Y; Tagawa, M; Taguchi, A; Watanabe, T; Yabuki, M; Yamaguchi, N | 1 |
| Nussbaum, AM; Stroup, TS | 1 |
| Bae, KY; Chung, YC; Kim, JM; Kim, SW; Kim, SY; Lee, JH; Lee, YH; Shin, IS; Yoon, JS | 1 |
| Bocato, MZ; Calixto, LA; de Gaitani, CM; de Oliveira, AR; Pupo, MT; Simões, RA | 1 |
| Doran, AC; Mancuso, JY; Osgood, SM; Shaffer, CL | 1 |
| Aman, MG; Bies, RR; Saldaña, SN; Sherwin, CM; Vinks, AA | 1 |
| Den, R; Hirano, J; Ikai, S; Mamo, D; Mimura, M; Nishimoto, M; Remington, G; Suzuki, T; Takeuchi, H; Tsuboi, T; Tsunoda, K; Uchida, H; Watanabe, K | 1 |
| Druitt, T; Dunsdon, J; Purushothaman, S; Raj, V | 1 |
| Butzbach, DM; Byard, RW; Kobus, HJ; Lokan, RJ; Sims, DN; Stockham, PC; Walker, GS | 1 |
| Kandasamy, A | 1 |
| Baandrup, L; Glenthoj, B; Jennum, P; Lublin, H | 1 |
| Chae, SW; Choi, JM; Lee, HJ; Lee, KS; Park, JH; Rhie, SJ | 1 |
| Franch, J; Labad, J; López, X; Monseny, R; Montalvo, I; Ortega, L; Solé, M; Vilella, E | 1 |
| Boot, AM; Buitelaar, JK; Roke, Y; Tenback, D; van Harten, PN | 1 |
| Andrade, C; Suresh Kumar, PN | 1 |
| Carano, A; Cavuto, M; De Berardis, D; Di Giannantonio, M; Fornaro, M; Iasevoli, F; Lang, AP; Marini, S; Martinotti, G; Mazza, M; Perna, G; Piersanti, M; Valchera, A | 1 |
| Campistol, J; Darling, A; Perez-Duenas, B; Poo, P | 1 |
| Baseman, A; Berlin, JA; Gopal, S; Hough, D; Karcher, K; Kent, J; Nuamah, I; Palumbo, J; Xu, Y | 1 |
| Gen, K; Hibino, H; Inoue, Y; Matsumoto, H; Mikami, A; Mikami, K; Otomo, M; Suzuki, H | 2 |
| Alphs, L; Bossie, CA; Fu, DJ; Kern Sliwa, J; Ma, YW | 2 |
| Couchman, L; Fisher, DS; Flanagan, RJ; Handley, SA; Morgan, PE; Partridge, SJ | 1 |
| Kirk Morton, N; Zubek, D | 1 |
| Fisher, DS; Flanagan, RJ; Handley, SA; Partridge, SJ | 1 |
| Medvedovici, A; Rădulescu, FŞ; Ranetti, AE; Voicu, V | 1 |
| Fukui, N; Ono, S; Saito, M; Someya, T; Sugai, T; Suzuki, Y; Tsuneyama, N; Watanabe, J | 1 |
| Sakai, A; Sanjo, K; Takeuchi, K | 1 |
| Ahn, YM; Chang, SM; Joo, EJ; Kim, EY; Kim, JJ; Kim, YS; Shim, JC | 1 |
| Einarson, TR; Garg, M; Hemels, ME; Skoupá, J; Veselá, S; Zilbershtein, R | 1 |
| Berg, KA; Chavera, TA; Clarke, WP; Silva, M; Sullivan, LC | 1 |
| Einarson, TR; Hemels, ME; Jensen, R; Piwko, C; Pudas, H; Vicente, C; Zilbershtein, R | 1 |
| Boot, AM; Buitelaar, JK; Franke, B; Galesloot, TE; Roke, Y; van Harten, PN | 1 |
| Fudala, PJ; Gomeni, R; Heidbreder, C; Nasser, AF | 1 |
| D'Souza, S; DeLuca, P; Faraj, J | 1 |
| Gen, K; Hibino, H; Inoue, Y; Matsumoto, H; Mikami, A; Mikami, K; Suzuki, H | 1 |
| Alphs, L; Bossie, CA; Fu, DJ; Ma, YW; Sliwa, JK | 1 |
| Kmietowicz, Z | 1 |
| Bø, CN; Einarson, TR; Hemels, ME; Jensen, R; Piwko, C; Pudas, H; Vicente, C; Zilbershtein, R | 1 |
| Aboul-Fotouh, S; Elgayar, N | 1 |
| Appolinário, JC; Bressan, RA; Campos, JA; de Oliveira, IR; Elkis, H; Gattaz, WF; Grabowski, HM; Henna, E; Lacerda, AL; Lawson, FL; Louzã, MR; Périco, Cde A; Quevedo, J; Rocha, FL; Ruschel, SI; Sacomani, E; Zorzetto Filho, D | 1 |
| Kwak, KH; Lee, SJ; Lim, MS; Seong, SJ; Yang, DS; Yoon, YR | 1 |
| Fudala, PJ; Gomeni, R; Heidbreder, C; Laffont, CM; Nasser, AF; Zheng, B | 2 |
| Alva, G; Brams, M; Citrome, L; Glick, ID; Hochfeld, M; Jackson, R; Kianifard, F; Mattingly, G; Meng, X; Pestreich, L; Weiden, PJ; Winseck, A | 1 |
| Jayathilake, K; Johnson, R; Kwentus, J; Lindenmayer, JP; Meltzer, HY; Share, DB | 1 |
| Hou, YC; Lai, CH | 1 |
| Barton, HA; Danhof, M; de Greef, R; Grimwood, S; Groothuis, GM; Johnson, M; Kozielska, M; Pilla Reddy, V; Proost, JH; Vermeulen, A | 1 |
| Budman, CL | 1 |
| Morrissette, DA; Stahl, SM | 1 |
| Alva, G; Citrome, L; Glick, ID; Jackson, R; Kianifard, F; Mattingly, G; Meng, X; Weiden, PJ; Winseck, A | 1 |
| Buchanan, RW; Carpenter, WT | 1 |
| Bieńkowski, P; Jastrzębska-Więsek, M; Kołaczkowski, M; Mierzejewski, P; Partyka, A; Wasik, A; Wesołowska, A | 1 |
| Fabbri, C; Kato, M; Kinoshita, T; Koshikawa, Y; Nishida, K; Onohara, A; Sakai, S; Serretti, A; Sunada, N; Takekita, Y; Yoshimura, M | 1 |
| Baymeeva, NV; Kaleda, VG; Miroshnichenko, II; Platova, AI | 1 |
| Crippa, A; Davis, JM; Leucht, S; Orsini, N; Patel, MX; Siafis, S | 1 |
| Fu, K; He, Y; Jiang, W; Liu, W; Lu, J; Wang, Z; Wu, R; Xu, Y; Yan, Y; Yang, Y; Zhao, J | 1 |
| Dai, G; Geng, L; Gu, H; Teng, Z; Xu, W | 1 |
57 review(s) available for isoxazoles and risperidone
| Article | Year |
|---|---|
New antipsychotics: classification, efficacy, and adverse effects.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Humans; Isoxazoles; Piperidines; Receptors, Dopamine; Receptors, Glutamate; Receptors, Neurotransmitter; Receptors, Serotonin; Remoxipride; Risperidone; Schizophrenia; Serotonin Antagonists; Sulpiride | 1991 |
Ethical issues in drug selection for schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Dyskinesia, Drug-Induced; Ethics, Medical; Humans; Informed Consent; Isoxazoles; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1993 |
New antipsychotic medications: do research results relate to clinical practice?
Topics: Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Dyskinesia, Drug-Induced; Humans; Isoxazoles; Neurologic Examination; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1993 |
Pharmacological profile of risperidone.
Topics: Antipsychotic Agents; Brain; Dose-Response Relationship, Drug; Haloperidol; Humans; Isoxazoles; Metabolic Clearance Rate; Piperidines; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia; Schizophrenic Psychology | 1993 |
Clinical review of risperidone.
Topics: Antipsychotic Agents; Clinical Trials, Phase III as Topic; Humans; Isoxazoles; Multicenter Studies as Topic; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1993 |
Clinical considerations in the use of risperidone.
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1993 |
Newer antipsychotic drugs. A review of their pharmacology and therapeutic potential.
Topics: Antipsychotic Agents; Clozapine; Humans; Isoxazoles; Piperidines; Remoxipride; Risperidone; Schizophrenia; Treatment Outcome | 1993 |
Risperidone.
Topics: Antipsychotic Agents; Drug Interactions; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
The new atypical antipsychotics. A lack of extrapyramidal side-effects and new routes in schizophrenia research.
Topics: Antipsychotic Agents; Brain; Clozapine; Dyskinesia, Drug-Induced; Extrapyramidal Tracts; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Receptors, Dopamine; Receptors, Serotonin; Remoxipride; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Risperidone: clinical issues in treatment.
Topics: Antipsychotic Agents; Drug Approval; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1994 |
Extrapyramidal side effects and tolerability of risperidone: a review.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Dystonia; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
Dopamine antagonists in tic-related and psychotic spectrum obsessive compulsive disorder.
Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Clomipramine; Clozapine; Dopamine Antagonists; Drug Therapy, Combination; Female; Fluvoxamine; Haloperidol; Humans; Isoxazoles; Male; Obsessive-Compulsive Disorder; Piperidines; Risperidone; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Tic Disorders; Tourette Syndrome | 1994 |
The potential benefits of serotonin receptor-specific agents.
Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Humans; Isoxazoles; Ondansetron; Piperazines; Piperidines; Receptors, Serotonin; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin; Sumatriptan; Triazoles | 1994 |
The effects of clozapine on neurocognition: an overview.
Topics: Clozapine; Cognition; Cognition Disorders; Dopamine; Humans; Isoxazoles; Neuropsychological Tests; Piperidines; Receptors, Dopamine; Receptors, Muscarinic; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1994 |
Risperidone. A review of its pharmacology and therapeutic potential in the treatment of schizophrenia.
Topics: Absorption; Adult; Aged; Aging; Animals; Antipsychotic Agents; Central Nervous System; Cross-Over Studies; Disease Models, Animal; Drug Interactions; Hemodynamics; Humans; Isoxazoles; Neurosecretory Systems; Piperidines; Risperidone; Schizophrenia; Synaptic Transmission; Tissue Distribution | 1994 |
Survey on the pharmacodynamics of the new antipsychotic risperidone.
Topics: Animals; Antipsychotic Agents; Humans; Isoxazoles; Piperidines; Risperidone; Serotonin Antagonists | 1994 |
Risperidone: neurochemical, pharmacologic and clinical properties of a new antipsychotic drug.
Topics: Antipsychotic Agents; Brain; Clinical Trials as Topic; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Pathophysiology and treatment of negative symptoms.
Topics: Antipsychotic Agents; Brain; Depression; Dose-Response Relationship, Drug; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Pharmacotherapy of schizophrenia: a review.
Topics: Antipsychotic Agents; Brain; Clozapine; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Recent advances in the pharmacotherapy of schizophrenia.
Topics: Adult; Antipsychotic Agents; Brain; Clozapine; Dopamine; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
Risperidone: review of its pharmacology and therapeutic use in schizophrenia.
Topics: Antipsychotic Agents; Clinical Trials as Topic; Humans; Isoxazoles; Piperidines; Placebos; Risperidone; Schizophrenia; Treatment Outcome | 1994 |
[New psychopharmacologic alternatives in treatment of schizophrenia].
Topics: Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Isoxazoles; Piperidines; Psychotropic Drugs; Remoxipride; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Clinical efficacy of serotonin-dopamine antagonists relative to classic neuroleptics.
Topics: Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Dopamine Antagonists; Humans; Imidazoles; Indoles; Isoxazoles; Olanzapine; Piperidines; Pirenzepine; Risperidone; Schizophrenia; Serotonin Antagonists | 1995 |
Brief comparison of the pharmacokinetics and pharmacodynamics of the traditional and newer antipsychotic drugs.
Topics: Antipsychotic Agents; Chlorpromazine; Clozapine; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Time Factors | 1995 |
Clinical use of the newer antipsychotic drugs.
Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Female; Formularies as Topic; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia | 1995 |
A risk-benefit assessment of risperidone in schizophrenia.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Piperidines; Risk; Risperidone; Schizophrenia | 1995 |
Serotonin, schizophrenia and antipsychotic drug action.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Humans; Isoxazoles; Piperazines; Piperidines; Risperidone; Schizophrenia; Serotonin; Tryptophan | 1995 |
Prospects for pharmacotherapy of schizophrenia.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Humans; Isoxazoles; Piperidines; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia | 1995 |
The negative component in schizophrenia.
Topics: Affective Symptoms; Antipsychotic Agents; Haloperidol; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
New pharmacotherapeutic modalities for negative symptoms in psychosis.
Topics: Affective Symptoms; Antipsychotic Agents; Clozapine; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Risperidone; Schizophrenia; Schizophrenic Psychology; Syndrome | 1995 |
Long-term treatment of mood disorders in schizophrenia.
Topics: Affective Symptoms; Antidepressive Agents; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Isoxazoles; Lithium; Long-Term Care; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
Principal components and further possibilities with the PANSS.
Topics: Affective Symptoms; Antipsychotic Agents; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Reproducibility of Results; Risperidone; Schizophrenia; Schizophrenic Psychology; Syndrome | 1995 |
Antipsychotic medication in the treatment of schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
A pharmacological, pharmacokinetic and clinical overview of risperidone, a new antipsychotic that blocks serotonin 5-HT2 and dopamine D2 receptors.
Topics: Animals; Antipsychotic Agents; Dopamine D2 Receptor Antagonists; Humans; Isoxazoles; Piperidines; Risperidone; Serotonin Antagonists | 1995 |
Risperidone: review and assessment of its role in the treatment of schizophrenia.
Topics: Antipsychotic Agents; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1995 |
Treatment of schizophrenia.
Topics: Antipsychotic Agents; Behavior Therapy; Clozapine; Cognitive Behavioral Therapy; Family Therapy; Humans; Isoxazoles; Piperidines; Psychotherapy; Rehabilitation, Vocational; Risperidone; Schizophrenia | 1995 |
Advances in atypical antipsychotics for the treatment of schizophrenia: new formulations and new agents.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dosage Forms; Humans; Isoxazoles; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quinolones; Risperidone; Schizophrenia; Thiazoles | 2002 |
Rapidly disintegrating risperidone in subjects with schizophrenia or schizoaffective disorder: a summary of ten phase I clinical trials assessing taste, tablet disintegration time, bioequivalence, and tolerability.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Chemistry, Pharmaceutical; Clinical Trials, Phase I as Topic; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Patient Compliance; Patient Satisfaction; Psychotic Disorders; Pyrimidines; Risperidone; Schizophrenia; Solubility; Tablets; Taste; Therapeutic Equivalency | 2007 |
Forty years of antipsychotic Drug research--from haloperidol to paliperidone--with Dr. Paul Janssen.
Topics: Antipsychotic Agents; Haloperidol; History, 20th Century; History, 21st Century; Humans; Isoxazoles; Paliperidone Palmitate; Pimozide; Psychotic Disorders; Pyrimidines; Risperidone; Structure-Activity Relationship | 2007 |
Paliperidone for schizophrenia.
Topics: Antipsychotic Agents; Controlled Clinical Trials as Topic; Delayed-Action Preparations; Drug Interactions; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia | 2008 |
Paliperidone for schizophrenia.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia | 2008 |
Expected clinical benefits of paliperidone extended-release formulation when compared with risperidone immediate-release.
Topics: Antipsychotic Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia; Treatment Outcome | 2009 |
Akathisia and second-generation antipsychotic drugs.
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Isoxazoles; Olanzapine; Piperazines; Piperidines; Prevalence; Psychomotor Agitation; Psychotic Disorders; Quetiapine Fumarate; Quinolones; Risk Factors; Risperidone; Sulpiride; Thiazoles | 2009 |
Efficacy and safety of atypical antipsychotic drugs (quetiapine, risperidone, aripiprazole and paliperidone) compared with placebo or typical antipsychotic drugs for treating refractory schizophrenia: overview of systematic reviews.
Topics: Antipsychotic Agents; Aripiprazole; Dibenzothiazepines; Humans; Isoxazoles; Meta-Analysis as Topic; Paliperidone Palmitate; Piperazines; Placebos; Pyrimidines; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Review Literature as Topic; Risperidone; Schizophrenia; Treatment Outcome | 2010 |
Risperidone in schizophrenia: is there a role for therapeutic drug monitoring?
Topics: Antipsychotic Agents; Drug Monitoring; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia | 2011 |
Oral paliperidone extended-release: chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability.
Topics: Administration, Oral; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Half-Life; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia | 2012 |
Paliperidone palmitate for schizophrenia.
Topics: Antipsychotic Agents; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Palmitates; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia | 2012 |
Second-generation long-acting injectable antipsychotic agents: an overview.
Topics: Antipsychotic Agents; Benzodiazepines; Delayed-Action Preparations; Drug Costs; Humans; Injections; Isoxazoles; Monitoring, Physiologic; Olanzapine; Paliperidone Palmitate; Practice Guidelines as Topic; Pyrimidines; Risperidone; Schizophrenia | 2012 |
Treatment options for residual insomnia in schizophrenia.
Topics: Antipsychotic Agents; Central Nervous System Depressants; Humans; Isoxazoles; Melatonin; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia; Sleep Initiation and Maintenance Disorders | 2013 |
Efficacy and safety of long acting injectable atypical antipsychotics: a review.
Topics: Antipsychotic Agents; Benzodiazepines; Delayed-Action Preparations; Drug Delivery Systems; Humans; Injections; Isoxazoles; Medication Adherence; Olanzapine; Paliperidone Palmitate; Palmitates; Risperidone; Schizophrenia | 2013 |
[Medication-related oculogyric crises: a description of four cases and a review of the literature].
Topics: Adolescent; Anticonvulsants; Antipsychotic Agents; Aripiprazole; Child; Child Behavior Disorders; Child, Preschool; Dopamine; Dopamine Antagonists; Down Syndrome; Dyskinesia, Drug-Induced; Dystonic Disorders; Electroencephalography; Epilepsy; Female; Fragile X Syndrome; Humans; Intellectual Disability; Isoxazoles; Male; Methotrimeprazine; Ocular Motility Disorders; Paliperidone Palmitate; Piperazines; Pyrimidines; Quinolones; Risperidone; Substance Withdrawal Syndrome; Translocation, Genetic; Valproic Acid | 2013 |
Risk of cardiovascular morbidity with risperidone or paliperidone treatment: analysis of 64 randomized, double-blind trials.
Topics: Antipsychotic Agents; Cardiovascular Diseases; Databases, Factual; Drug Labeling; Humans; Incidence; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Randomized Controlled Trials as Topic; Risk; Risperidone | 2013 |
Drug-induced hypo- and hyperprolactinemia: mechanisms, clinical and therapeutic consequences.
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Blood-Brain Barrier; Humans; Hyperprolactinemia; Isoxazoles; Paliperidone Palmitate; Piperazines; Prolactin; Pyrimidines; Quinolones; Receptors, Dopamine D2; Risperidone; Stress, Psychological; Sulpiride; Xenobiotics | 2013 |
[Paliperidone, risperidone].
Topics: Antipsychotic Agents; Humans; Isoxazoles; Japan; Paliperidone Palmitate; Pyrimidines; Receptor, Serotonin, 5-HT2A; Risperidone; Schizophrenia; Treatment Outcome | 2013 |
The role of atypical antipsychotics for treatment of Tourette's syndrome: an overview.
Topics: Antipsychotic Agents; Aripiprazole; Clinical Trials as Topic; Humans; Isoxazoles; Paliperidone Palmitate; Piperazines; Pyrimidines; Quinolones; Risperidone; Tourette Syndrome; Treatment Outcome | 2014 |
Treating the violent patient with psychosis or impulsivity utilizing antipsychotic polypharmacy and high-dose monotherapy.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brain; Clozapine; Dibenzocycloheptenes; Drug Therapy, Combination; Heterocyclic Compounds, 4 or More Rings; Humans; Impulsive Behavior; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Polypharmacy; Psychotic Disorders; Quetiapine Fumarate; Receptors, Dopamine D2; Risperidone; Thiazoles; Violence | 2014 |
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia.
Topics: Acute Disease; Administration, Oral; Antipsychotic Agents; Aripiprazole; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Haloperidol; Humans; Imidazoles; Indoles; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles; Thiophenes | 2020 |
105 trial(s) available for isoxazoles and risperidone
| Article | Year |
|---|---|
The Swedish version of the Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Construct validity and interrater reliability.
Topics: Antipsychotic Agents; Chronic Disease; Cross-Cultural Comparison; Double-Blind Method; Haloperidol; Humans; Isoxazoles; Observer Variation; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Reproducibility of Results; Risperidone; Schizophrenia; Schizophrenic Psychology; Sweden | 1992 |
Risperidone versus haloperidol in the treatment of chronic schizophrenic inpatients: a multicentre double-blind comparative study.
Topics: Adult; Aged; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Female; Haloperidol; Hospitalization; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1992 |
Ventricular enlargement, clinical correlates and treatment outcome in chronic schizophrenic inpatients.
Topics: Adult; Aged; Antipsychotic Agents; Brain; Cerebral Ventricles; Chronic Disease; Dilatation, Pathologic; Double-Blind Method; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Tomography, X-Ray Computed | 1992 |
Risperidone, a new antipsychotic with serotonin 5-HT2 and dopamine D2 antagonistic properties.
Topics: Antipsychotic Agents; Dopamine Antagonists; Double-Blind Method; Electrocardiography; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Risperidone; Schizophrenia; Serotonin Antagonists | 1992 |
Risperidone in the treatment of chronic schizophrenic patients: an international double-blind parallel-group study versus haloperidol. The International Risperidone Research Group.
Topics: Antipsychotic Agents; Double-Blind Method; Haloperidol; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1992 |
Risperidone: clinical development: north American results.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Humans; Isoxazoles; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia | 1992 |
Risperidone: clinical safety and efficacy in schizophrenia.
Topics: Adult; Antipsychotic Agents; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1992 |
Pilot clinical investigation of risperidone in the treatment of psychotic patients.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Brief Psychiatric Rating Scale; Drug Evaluation; Female; Humans; Isoxazoles; Male; Middle Aged; Pilot Projects; Piperidines; Psychotic Disorders; Risperidone | 1990 |
New antipsychotics: classification, efficacy, and adverse effects.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Humans; Isoxazoles; Piperidines; Receptors, Dopamine; Receptors, Glutamate; Receptors, Neurotransmitter; Receptors, Serotonin; Remoxipride; Risperidone; Schizophrenia; Serotonin Antagonists; Sulpiride | 1991 |
Thymosthenic agents, a novel approach in the treatment of schizophrenia.
Topics: Brain; Butyrophenones; Humans; Isoxazoles; Piperidines; Pyrimidinones; Randomized Controlled Trials as Topic; Receptors, Serotonin; Risperidone; Ritanserin; Schizophrenia; Schizophrenic Psychology; Serotonin Antagonists | 1989 |
Risperidone versus perphenazine in the treatment of chronic schizophrenic patients with acute exacerbations.
Topics: Acute Disease; Adult; Aged; Antipsychotic Agents; Denmark; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Norway; Parkinson Disease, Secondary; Perphenazine; Piperidines; Prevalence; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index | 1993 |
Risperidone versus clozapine in the treatment of schizophrenic patients with acute symptoms: a double blind, randomized trial.
Topics: Acute Disease; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Double-Blind Method; Electrocardiography; Electroencephalography; Female; Humans; Infant, Newborn; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia, Paranoid | 1994 |
Risperidone in the treatment of schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Double-Blind Method; Drug Administration Schedule; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Placebos; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1994 |
Symptoms in schizophrenic syndromes in relation to age, sex, duration of illness and number of previous hospitalizations.
Topics: Adult; Age Factors; Age of Onset; Aged; Antipsychotic Agents; Female; Haloperidol; Hospitalization; Hospitals, Psychiatric; Humans; Isoxazoles; Male; Middle Aged; Patient Admission; Piperidines; Risperidone; Ritanserin; Schizophrenia; Schizophrenic Psychology; Sex Factors | 1994 |
Efficacy of risperidone on positive features of schizophrenia.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Haloperidol; Humans; Isoxazoles; Piperidines; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia; Treatment Outcome | 1994 |
Negative symptoms in schizophrenia: assessment of the effect of risperidone.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia; Single-Blind Method | 1994 |
Changes in single symptoms and separate factors of the schizophrenic syndrome after treatment with risperidone or haloperidol.
Topics: Double-Blind Method; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
Risperidone. A review of its pharmacology and therapeutic potential in the treatment of schizophrenia.
Topics: Absorption; Adult; Aged; Aging; Animals; Antipsychotic Agents; Central Nervous System; Cross-Over Studies; Disease Models, Animal; Drug Interactions; Hemodynamics; Humans; Isoxazoles; Neurosecretory Systems; Piperidines; Risperidone; Schizophrenia; Synaptic Transmission; Tissue Distribution | 1994 |
Desmopressin for risperidone-induced enuresis.
Topics: Administration, Intranasal; Adult; Antipsychotic Agents; Deamino Arginine Vasopressin; Double-Blind Method; Enuresis; Female; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone.
Topics: Adult; Antipsychotic Agents; Brain Chemistry; Cerebellum; Cerebral Cortex; Dopamine Antagonists; Humans; Isoxazoles; Male; Piperidines; Raclopride; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Tomography, Emission-Computed | 1993 |
Pharmacokinetics of risperidone in chronic schizophrenic patients.
Topics: Adolescent; Adult; Antipsychotic Agents; Chronic Disease; Cross-Over Studies; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia; Therapeutic Equivalency | 1994 |
Risperidone and clozapine in the treatment of drug-resistant schizophrenia and neuroleptic-induced supersensitivity psychosis.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Resistance; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Psychoses, Substance-Induced; Risperidone; Schizophrenia; Schizophrenic Psychology; Sex Characteristics | 1994 |
Dopamine D2 receptor blockade in vivo with the novel antipsychotics risperidone and remoxipride--an 123I-IBZM single photon emission tomography (SPET) study.
Topics: Adult; Antipsychotic Agents; Basal Ganglia; Benzamides; Cerebral Cortex; Dopamine D2 Receptor Antagonists; Female; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Isoxazoles; Male; Middle Aged; Neostriatum; Piperidines; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrrolidines; Remoxipride; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1995 |
Effects of risperidone in tardive dyskinesia: an analysis of the Canadian multicenter risperidone study.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia | 1995 |
Randomized, double-blind, controlled trial of risperidone versus clozapine in patients with chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Clozapine; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
A path-analytical approach to differentiate between direct and indirect drug effects on negative symptoms in schizophrenic patients. A re-evaluation of the North American risperidone study.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chronic Disease; Double-Blind Method; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1995 |
The negative component in schizophrenia.
Topics: Affective Symptoms; Antipsychotic Agents; Haloperidol; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
New pharmacotherapeutic modalities for negative symptoms in psychosis.
Topics: Affective Symptoms; Antipsychotic Agents; Clozapine; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Risperidone; Schizophrenia; Schizophrenic Psychology; Syndrome | 1995 |
Risperidone versus zuclopenthixol in the treatment of acute schizophrenic episodes: a double-blind parallel-group trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Clopenthixol; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
Critique of the Canadian Multicenter Placebo-Controlled Study of Risperidone and Haloperidol.
Topics: Canada; Double-Blind Method; Haloperidol; Humans; Isoxazoles; Piperidines; Research Design; Risperidone; Schizophrenia | 1995 |
Risperidone in the treatment of patients with chronic schizophrenia: a multi-national, multi-centre, double-blind, parallel-group study versus haloperidol. Risperidone Study Group.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Haloperidol; Humans; Isoxazoles; Male; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
Risperidone in the treatment of affective illness and obsessive-compulsive disorder.
Topics: Adult; Ambulatory Care; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Obsessive-Compulsive Disorder; Piperidines; Prospective Studies; Psychiatric Status Rating Scales; Risperidone; Treatment Outcome | 1995 |
A PET study of D2 and 5-HT2 receptor occupancy induced by risperidone in poor metabolizers of debrisoquin and risperidone.
Topics: Adult; Antipsychotic Agents; Debrisoquin; Genotype; Humans; Isoxazoles; Male; Piperidines; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Tomography, Emission-Computed | 1995 |
Risperidone as add-on therapy in behavioural disturbances in mental retardation: a double-blind placebo-controlled cross-over study.
Topics: Adolescent; Adult; Antipsychotic Agents; Basal Ganglia Diseases; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intellectual Disability; Isoxazoles; Male; Mental Disorders; Middle Aged; Piperidines; Placebos; Risperidone | 1993 |
A Canadian multicenter placebo-controlled study of fixed doses of risperidone and haloperidol in the treatment of chronic schizophrenic patients.
Topics: Adult; Aged; Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Neurologic Examination; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1993 |
Risperidone versus haloperidol in the treatment of chronic schizophrenic patients: a parallel group double-blind comparative trial.
Topics: Adolescent; Adult; Chronic Disease; Double-Blind Method; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia | 1993 |
Quantitative electroencephalogram examination of effects of risperidone in schizophrenic patients.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Dominance, Cerebral; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Evoked Potentials; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Schizophrenia; Schizophrenic Psychology; Social Behavior | 1993 |
Double-blind comparison of risperidone and haloperidol in schizophrenic and schizoaffective psychoses.
Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Double-Blind Method; Female; Haloperidol; Humans; Isoxazoles; Male; Piperidines; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology | 1993 |
Plasma concentrations of risperidone and its 9-hydroxy metabolite and their relationship to dose in schizophrenic patients: simultaneous determination by a high performance liquid chromatography with electrochemical detection.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia | 1998 |
Serum concentrations and side effects in psychiatric patients during risperidone therapy.
Topics: Adult; Aged; Antipsychotic Agents; Cross-Sectional Studies; Cytochrome P-450 CYP2D6; Drug Interactions; Female; Genotype; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Psychotropic Drugs; Pyrimidines; Risperidone | 1998 |
Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone.
Topics: Adult; Alleles; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Female; Genotype; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pyrimidines; Risperidone; Schizophrenia | 1999 |
Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: a pilot study.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depression; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Dystonia; Female; Humans; Isoxazoles; Male; Mianserin; Middle Aged; Mirtazapine; Paliperidone Palmitate; Pilot Projects; Psychotic Disorders; Pyrimidines; Risperidone; Severity of Illness Index; Treatment Outcome | 1999 |
Determination of risperidone and 9-hydroxyrisperidone in human plasma by high-performance liquid chromatography: application to therapeutic drug monitoring in Japanese patients with schizophrenia.
Topics: Adult; Aged; Antipsychotic Agents; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Monitoring; Female; Humans; Isoxazoles; Japan; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Reproducibility of Results; Risperidone; Schizophrenia; Sensitivity and Specificity | 1999 |
Risperidone in acutely exacerbated schizophrenia: dosing strategies and plasma levels.
Topics: Acute Disease; Adult; Antipsychotic Agents; Asian People; Drug Administration Schedule; Female; Hospitalization; Humans; Isoxazoles; Male; Paliperidone Palmitate; Patient Readmission; Pharmacogenetics; Prospective Studies; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Taiwan; Treatment Outcome | 2000 |
Effect of risperidone on plasma free 3-methoxy-4-hydroxyphenylglycol (pMHPG) levels in schizophrenic patients: relationship among plasma concentrations of risperidone and 9-hydroxyrisperidone, pMHPG levels, and clinical improvement.
Topics: Adolescent; Adult; Antipsychotic Agents; Female; Humans; Isoxazoles; Male; Methoxyhydroxyphenylglycol; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia; Serotonin Antagonists; Treatment Outcome | 2000 |
Relationship between plasma risperidone and 9-hydroxyrisperidone concentrations and clinical response in patients with schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Chromatography, High Pressure Liquid; Chronic Disease; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 2001 |
Pharmacokinetic and safety assessments of galantamine and risperidone after the two drugs are administered alone and together.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Area Under Curve; Biological Availability; Cholinesterase Inhibitors; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Interactions; Female; Galantamine; Gas Chromatography-Mass Spectrometry; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone; Time Factors | 2002 |
Pharmacokinetic comparison of fast-disintegrating and conventional tablet formulations of risperidone in healthy volunteers.
Topics: Adult; Antipsychotic Agents; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Female; Humans; Isoxazoles; Male; Metabolic Clearance Rate; Middle Aged; Paliperidone Palmitate; Pyrimidines; Radioimmunoassay; Risperidone; Tablets; Therapeutic Equivalency; Time Factors | 2003 |
Correlation between scores on Continuous Performance Test and plasma concentration for schizophrenic patients on risperidone.
Topics: Adult; Antipsychotic Agents; Attention; Brief Psychiatric Rating Scale; Discrimination Learning; Dose-Response Relationship, Drug; Female; Humans; Isoxazoles; Male; Neurologic Examination; Neuropsychological Tests; Paliperidone Palmitate; Pattern Recognition, Visual; Psychometrics; Psychomotor Performance; Pyrimidines; Reaction Time; Risperidone; Schizophrenia; Schizophrenic Psychology; Statistics as Topic; Treatment Outcome | 2004 |
Risperidone treatment of children with autistic disorder: effectiveness, tolerability, and pharmacokinetic implications.
Topics: Autistic Disorder; Child; Child, Preschool; Drug Tolerance; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Statistics, Nonparametric; Weight Gain | 2004 |
Plasma risperidone concentrations during combined treatment with sertraline.
Topics: Adult; Antipsychotic Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Psychotic Disorders; Pyrimidines; Risperidone; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sertraline | 2004 |
Risperidone plasma levels, clinical response and side-effects.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Dose-Response Relationship, Drug; Female; Genotype; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Prospective Studies; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia | 2005 |
Serum concentrations of risperidone and 9-hydroxyrisperidone after administration of the long-acting injectable form of risperidone: evidence from a routine therapeutic drug monitoring service.
Topics: Administration, Oral; Adult; Aged; Delayed-Action Preparations; Drug Administration Schedule; Drug Monitoring; Female; Humans; Injections, Intramuscular; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia | 2005 |
Pharmacokinetics and D2 receptor occupancy of long-acting injectable risperidone (Risperdal Consta) in patients with schizophrenia.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Binding, Competitive; Brain; Delayed-Action Preparations; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Image Processing, Computer-Assisted; Injections, Intramuscular; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Positron-Emission Tomography; Pyrimidines; Radioimmunoassay; Receptors, Dopamine D2; Risperidone; Schizophrenia; Scintillation Counting | 2005 |
Effect of verapamil on pharmacokinetics and pharmacodynamics of risperidone: in vivo evidence of involvement of P-glycoprotein in risperidone disposition.
Topics: Administration, Oral; Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Chromatography, Liquid; Cross-Over Studies; Cytochrome P-450 CYP2D6; Drug Administration Schedule; Drug Synergism; Genotype; Half-Life; Humans; Immunoenzyme Techniques; Isoxazoles; Japan; Male; Paliperidone Palmitate; Patient Selection; Prolactin; Pyrimidines; Risperidone; Statistics as Topic; Verapamil | 2005 |
Dose-dependent interaction of paroxetine with risperidone in schizophrenic patients.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Paroxetine; Pyrimidines; Risperidone; Schizophrenia | 2005 |
Cytochrome P450 3A inhibitor itraconazole affects plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients.
Topics: Adult; Antifungal Agents; Antipsychotic Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Genotype; Half-Life; Humans; Isoxazoles; Itraconazole; Male; Middle Aged; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia | 2005 |
Pharmacokinetics and bioequivalence evaluation of risperidone in healthy male subjects with different CYP2D6 genotypes.
Topics: Administration, Oral; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Genotype; Humans; Isoxazoles; Korea; Male; Paliperidone Palmitate; Polymorphism, Single Nucleotide; Pyrimidines; Risperidone; Solubility; Tablets; Therapeutic Equivalency | 2006 |
Population pharmacokinetics of risperidone and 9-hydroxyrisperidone in patients with acute episodes associated with bipolar I disorder.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Antipsychotic Agents; Bipolar Disorder; Computer Simulation; Cytochrome P-450 CYP2D6; Databases as Topic; Drug Administration Schedule; Female; Humans; Isoxazoles; Linear Models; Male; Middle Aged; Models, Biological; Paliperidone Palmitate; Phenotype; Population Surveillance; Pyrimidines; Reproducibility of Results; Risperidone; Tablets | 2007 |
Prolactin release in children treated with risperidone: impact and role of CYP2D6 metabolism.
Topics: Adolescent; Age Factors; Antipsychotic Agents; Child; Child Development Disorders, Pervasive; Child, Preschool; Cytochrome P-450 CYP2D6; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Prolactin; Prospective Studies; Pyrimidines; Risperidone | 2007 |
A study of genetic (CYP2D6 and ABCB1) and environmental (drug inhibitors and inducers) variables that may influence plasma risperidone levels.
Topics: Adult; Aging; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Female; Humans; Isoxazoles; Linear Models; Male; Middle Aged; Organic Anion Transporters; Paliperidone Palmitate; Pyrimidines; Risperidone; Sex Factors | 2007 |
Lack of bioequivalence between generic risperidone oral solution and originator risperidone tablets.
Topics: Administration, Oral; Adolescent; Adult; Antipsychotic Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Confidence Intervals; Cross-Over Studies; Drugs, Generic; Female; Humans; Isoxazoles; Male; Mass Spectrometry; Middle Aged; Paliperidone Palmitate; Pharmaceutical Solutions; Pyrimidines; Risperidone; Tablets; Therapeutic Equivalency | 2007 |
Plasma pharmacokinetic characteristics of risperidone and their relationship to saliva concentrations in children with psychiatric or neurodevelopmental disorders.
Topics: Adolescent; Antipsychotic Agents; Area Under Curve; Child; Child, Preschool; Cytochrome P-450 CYP2D6; Developmental Disabilities; Female; Genotype; Half-Life; Humans; Isoxazoles; Male; Mental Disorders; Paliperidone Palmitate; Pyrimidines; Risperidone; Saliva | 2007 |
Effect of rifampin, an inducer of CYP3A and P-glycoprotein, on the pharmacokinetics of risperidone.
Topics: Administration, Oral; Adult; Alleles; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Genotype; Half-Life; Humans; Isoxazoles; Male; Metabolic Clearance Rate; Paliperidone Palmitate; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyrimidines; Rifampin; Risperidone; Time Factors | 2008 |
Paliperidone extended-release tablets in schizophrenia patients previously treated with risperidone.
Topics: Adult; Antipsychotic Agents; Double-Blind Method; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia | 2008 |
The disparity of pharmacokinetics and prolactin study for risperidone long-acting injection.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Female; Humans; Hyperprolactinemia; Injections, Intramuscular; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Prolactin; Pyrimidines; Research Design; Risperidone; Schizophrenia; Schizophrenic Psychology | 2008 |
Bioequivalence evaluation of two strengths of risperidone tablet formulations in healthy volunteers.
Topics: Adult; Antipsychotic Agents; Area Under Curve; Chromatography, Liquid; Cross-Over Studies; European Union; Female; Guidelines as Topic; Humans; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency; Time Factors; United States; United States Food and Drug Administration; Young Adult | 2009 |
A comparison of serum prolactin concentrations after administration of paliperidone extended-release and risperidone tablets in patients with schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Area Under Curve; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypotension, Orthostatic; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Prolactin; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Young Adult | 2010 |
Medication satisfaction in schizophrenia: a blinded-initiation study of paliperidone extended release in patients suboptimally responsive to risperidone.
Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Patient Satisfaction; Pyrimidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 2010 |
Effect of CYP2D6, CYP3A5, and MDR1 genetic polymorphisms on the pharmacokinetics of risperidone and its active moiety.
Topics: Adult; Alleles; Antipsychotic Agents; Area Under Curve; Asian People; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Genotype; Humans; Isoxazoles; Male; Paliperidone Palmitate; Polymorphism, Genetic; Pyrimidines; Risperidone | 2010 |
Long-acting injectable risperidone and metabolic ratio: a possible index of clinical outcome in treatment-resistant schizophrenic patients.
Topics: Adolescent; Adult; Antipsychotic Agents; Biomarkers, Pharmacological; Brief Psychiatric Rating Scale; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Monitoring; Drug Resistance; Female; Humans; Injections, Intramuscular; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Severity of Illness Index | 2010 |
Gender differences in the relationship between the risperidone metabolism and the plasma prolactin levels in psychiatric patients.
Topics: Adult; Aged; Chromatography, Liquid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Isoxazoles; Male; Mental Disorders; Middle Aged; Paliperidone Palmitate; Prolactin; Pyrimidines; Risperidone; Sex Characteristics; Tandem Mass Spectrometry; Young Adult | 2010 |
Armodafinil as adjunctive therapy in adults with cognitive deficits associated with schizophrenia: a 4-week, double-blind, placebo-controlled study.
Topics: Adult; Antipsychotic Agents; Benzhydryl Compounds; Benzodiazepines; Central Nervous System Stimulants; Cognition Disorders; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Modafinil; Olanzapine; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Treatment Outcome | 2010 |
A double-blind study of paliperidone palmitate and risperidone long-acting injectable in adults with schizophrenia.
Topics: Adolescent; Adult; Analysis of Variance; Antipsychotic Agents; Double-Blind Method; Drug Delivery Systems; Female; Humans; Isoxazoles; Least-Squares Analysis; Male; Middle Aged; Paliperidone Palmitate; Palmitates; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Time Factors; Treatment Outcome; Young Adult | 2011 |
Association of 9-hydroxy risperidone concentrations with risk of switching or discontinuation in the clinical antipsychotic trial of intervention effectiveness-Alzheimer's disease trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Proportional Hazards Models; Pyrimidines; Risperidone; Time Factors; Treatment Outcome | 2010 |
Relative bioavailability of two oral formulations of risperidone 2 mg: A single-dose, randomized-sequence, open-label, two-period crossover comparison in healthy Brazilian volunteers.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Area Under Curve; Biological Availability; Brazil; Chromatography, Liquid; Cross-Over Studies; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone; Tandem Mass Spectrometry; Therapeutic Equivalency | 2010 |
Relative bioavailability and pharmacokinetic comparison of two 2-mg risperidone tablet formulations: A single dose, randomized-sequence, double-blind, 2-way crossover study in healthy male volunteers in Thailand.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drugs, Generic; Humans; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Tablets; Thailand; Young Adult | 2010 |
A comparative study of paliperidone palmitate and risperidone long-acting injectable therapy in schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Data Interpretation, Statistical; Delayed-Action Preparations; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Dyskinesia, Drug-Induced; Endpoint Determination; Female; Glucose; Heart Diseases; Humans; Injections, Intramuscular; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Palmitates; Prolactin; Psychiatric Status Rating Scales; Risperidone; Sample Size; Schizophrenia; Schizophrenic Psychology; Suicide; Treatment Outcome; Young Adult | 2011 |
Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of risperidone in healthy subjects with CYP2D6*10/*10.
Topics: Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP2D6; Genotype; Humans; Isoxazoles; Male; Paliperidone Palmitate; Polymorphism, Genetic; Pyrimidines; Retrospective Studies; Risperidone; Young Adult | 2011 |
Effect of cytochrome P450 3A4 inhibitor ketoconazole on risperidone pharmacokinetics in healthy volunteers.
Topics: Adult; Antipsychotic Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Enzyme Inhibitors; Half-Life; Humans; Isoxazoles; Ketoconazole; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Tandem Mass Spectrometry; Tissue Distribution; Young Adult | 2012 |
Effects of acute paliperidone palmitate treatment in subjects with schizophrenia recently treated with oral risperidone.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Palmitates; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Treatment Outcome | 2011 |
A randomized trial of paliperidone palmitate and risperidone long-acting injectable in schizophrenia.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Buttocks; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Injections, Intramuscular; Isoxazoles; Male; Paliperidone Palmitate; Palmitates; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Sleep Initiation and Maintenance Disorders; Treatment Outcome; White People | 2012 |
Analysis of gene variants previously associated with iloperidone response in patients with schizophrenia who are treated with risperidone.
Topics: Adult; Antipsychotic Agents; Apoptosis Regulatory Proteins; Benzodiazepines; Biomarkers, Pharmacological; Black or African American; Drug Resistance; Genotype; Humans; Isoxazoles; Membrane Proteins; Membrane Transport Proteins; Olanzapine; Piperidines; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Receptors, AMPA; Risperidone; Schizophrenia; White People | 2012 |
QT prolongation of the antipsychotic risperidone is predominantly related to its 9-hydroxy metabolite paliperidone.
Topics: Adult; Age Factors; Antipsychotic Agents; Dose-Response Relationship, Drug; Electrocardiography; Female; Humans; Isoxazoles; Long QT Syndrome; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Young Adult | 2012 |
Efficacy of iloperidone in the short-term treatment of schizophrenia: a post hoc analysis of pooled patient data from four phase III, placebo- and active-controlled trials.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Labeling; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperazines; Piperidines; Prospective Studies; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome; Young Adult | 2012 |
Predicting plasma concentration of risperidone associated with dosage change: a population pharmacokinetic study.
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Dose-Response Relationship, Drug; Female; Humans; Isoxazoles; Male; Middle Aged; Nonlinear Dynamics; Paliperidone Palmitate; Psychotic Disorders; Pyrimidines; Risperidone; Schizophrenia; Young Adult | 2012 |
Different impacts of aquaporin 4 and MAOA allele variation among olanzapine, risperidone, and paliperidone in schizophrenia.
Topics: Adult; Antipsychotic Agents; Aquaporin 4; Benzodiazepines; Diagnostic and Statistical Manual of Mental Disorders; Drug Monitoring; Female; Genetic Association Studies; Humans; Isoxazoles; Male; Middle Aged; Monoamine Oxidase; Olanzapine; Paliperidone Palmitate; Polymorphism, Genetic; Promoter Regions, Genetic; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Smoking; Young Adult | 2012 |
Different safety profiles of risperidone and paliperidone extended-release: a double-blind, placebo-controlled trial with healthy volunteers.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Chi-Square Distribution; Cognition; Double-Blind Method; Drug Administration Schedule; Drug Delivery Systems; Female; Humans; Isoxazoles; Male; Neuropsychological Tests; Pain Measurement; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Substance-Related Disorders; Time Factors | 2012 |
Population pharmacokinetic analysis of risperidone and 9-hydroxyrisperidone with genetic polymorphisms of CYP2D6 and ABCB1.
Topics: Adult; Alleles; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP2D6; Genotype; Humans; Isoxazoles; Male; Models, Biological; Paliperidone Palmitate; Polymorphism, Single Nucleotide; Pyrimidines; Risperidone; Young Adult | 2012 |
Paliperidone ER versus risperidone for neurocognitive function in patients with schizophrenia: a randomized, open-label, controlled trial.
Topics: Adolescent; Adult; Antipsychotic Agents; Cognition Disorders; Delayed-Action Preparations; Depression; Diagnostic and Statistical Manual of Mental Disorders; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Monitoring; Female; Humans; Isoxazoles; Male; Middle Aged; Movement Disorders; Paliperidone Palmitate; Prevalence; Psychiatric Status Rating Scales; Pyrimidines; Republic of Korea; Risperidone; Schizophrenia; Young Adult | 2012 |
Study of the efficacy and safety of switching from risperidone to paliperidone in elderly patients with schizophrenia.
Topics: Antipsychotic Agents; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Patient Satisfaction; Pyrimidines; Risperidone; Schizophrenia | 2013 |
Paliperidone palmitate versus risperidone long-acting injection in markedly-to-severely ill schizophrenia subjects: onset of efficacy with recommended initiation regimens.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Humans; Injections, Intramuscular; Isoxazoles; Male; Paliperidone Palmitate; Palmitates; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Severity of Illness Index; Treatment Outcome | 2014 |
Long-term effectiveness of flexibly dosed paliperidone extended-release: comparison among patients with schizophrenia switching from risperidone and other antipsychotic agents.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Prospective Studies; Pyrimidines; Risperidone; Schizophrenia; Severity of Illness Index | 2013 |
A model-based approach to characterize the population pharmacokinetics and the relationship between the pharmacokinetic and safety profiles of RBP-7000, a new, long-acting, sustained-released formulation of risperidone.
Topics: Adolescent; Adult; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Delayed-Action Preparations; Female; Humans; Injections, Subcutaneous; Isoxazoles; Male; Middle Aged; Models, Biological; Paliperidone Palmitate; Polyglactin 910; Prolactin; Pyrimidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Young Adult | 2013 |
The influence of switching from risperidone to paliperidone on the extrapyramidal symptoms and cognitive function in elderly patients with schizophrenia: a preliminary open-label trial.
Topics: Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Cognition Disorders; Drug Substitution; Dyskinesia, Drug-Induced; Female; Humans; Isoxazoles; Male; Memory, Short-Term; Neuropsychological Tests; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Severity of Illness Index; Treatment Outcome | 2014 |
Paliperidone palmitate versus oral risperidone and risperidone long-acting injection in patients with recently diagnosed schizophrenia: a tolerability and efficacy comparison.
Topics: Adult; Age of Onset; Antipsychotic Agents; Delayed-Action Preparations; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Female; Humans; Isoxazoles; Male; Muscle Rigidity; Paliperidone Palmitate; Palmitates; Prolactin; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Treatment Outcome | 2014 |
Switching from oral risperidone to flexibly dosed oral paliperidone extended-release: core symptoms, satisfaction, and quality of life in patients with stable but symptomatic schizophrenia: the RISPALI study.
Topics: Administration, Oral; Adult; Delayed-Action Preparations; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Patient Satisfaction; Prospective Studies; Pyrimidines; Quality of Life; Risperidone; Schizophrenia; Severity of Illness Index | 2014 |
Changes in plasma concentrations of risperidone and 9-hydroxyrisperidone and the associated clinical effects during the switch from oral risperidone to extended-release paliperidone tablets in patients with schizophrenia.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia; Time Factors; Young Adult | 2014 |
Population pharmacokinetics and prediction of dopamine D2 receptor occupancy after multiple doses of RBP-7000, a new sustained-release formulation of risperidone, in schizophrenia patients on stable oral risperidone treatment.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Humans; Injections, Subcutaneous; Isoxazoles; Male; Middle Aged; Models, Biological; Paliperidone Palmitate; Pyrimidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Young Adult | 2014 |
A trial evaluating gradual- or immediate-switch strategies from risperidone, olanzapine, or aripiprazole to iloperidone in patients with schizophrenia.
Topics: Adolescent; Adult; Analysis of Variance; Antipsychotic Agents; Aortic Bodies; Aripiprazole; Benzodiazepines; Cohort Studies; Drug Administration Schedule; Drug Substitution; Female; Humans; Isoxazoles; Male; Middle Aged; Olanzapine; Piperazines; Piperidines; Psychiatric Status Rating Scales; Quinolones; Risperidone; Schizophrenia; Surveys and Questionnaires; Treatment Outcome; Young Adult | 2014 |
A six month randomized controlled trial of long acting injectable risperidone 50 and 100mg in treatment resistant schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrimidines; Risperidone; Schizophrenia; Time Factors; Treatment Outcome; Young Adult | 2014 |
Onset and persistence of efficacy by symptom domain with long-acting injectable paliperidone palmitate in patients with schizophrenia.
Topics: Antipsychotic Agents; Double-Blind Method; Humans; Injections; Isoxazoles; Paliperidone Palmitate; Palmitates; Risperidone; Schizophrenia | 2014 |
Population pharmacokinetic modeling and simulation to guide dose selection for RBP-7000, a new sustained-release formulation of risperidone.
Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Female; Humans; Isoxazoles; Male; Middle Aged; Models, Biological; Paliperidone Palmitate; Palmitates; Pyrimidines; Risperidone | 2015 |
Switching to iloperidone: An omnibus of clinically relevant observations from a 12-week, open-label, randomized clinical trial in 500 persons with schizophrenia.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Dizziness; Female; Humans; Isoxazoles; Male; Olanzapine; Piperazines; Piperidines; Quinolones; Risperidone; Schizophrenia; Treatment Outcome | 2015 |
Cognitive function and risperidone long-acting injection vs. paliperidone palmitate in schizophrenia: a 6-month, open-label, randomized, pilot trial.
Topics: Adult; Antipsychotic Agents; Cognition; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Injections, Intramuscular; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Treatment Outcome | 2016 |
275 other study(ies) available for isoxazoles and risperidone
| Article | Year |
|---|---|
Determination of risperidone and 9-hydroxyrisperidone in plasma, urine and animal tissues by high-performance liquid chromatography.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Isoxazoles; Paliperidone Palmitate; Piperidines; Pyrimidines; Quality Control; Reproducibility of Results; Risperidone; Spectrophotometry, Ultraviolet | 1992 |
Pharmacological profile of the new potent neuroleptic ocaperidone (R 79,598).
Topics: Animals; Antiemetics; Antipsychotic Agents; Apomorphine; Behavior, Animal; Body Temperature; Dogs; Dopamine Agents; Dopamine Antagonists; Eating; Female; Haloperidol; Isoxazoles; Lethal Dose 50; Locomotion; Male; Mice; Motor Activity; Muscles; Neurotransmitter Agents; Piperidines; Posture; Pyrimidinones; Rats; Rats, Inbred Strains; Risperidone; Ritanserin; Serotonin; Serotonin Antagonists; Synaptic Transmission | 1992 |
Behavioral disinhibition and depression in amphetaminized rats: a comparison of risperidone, ocaperidone and haloperidol.
Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Isoxazoles; Male; Motor Activity; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Risperidone | 1992 |
In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone.
Topics: Animals; Antipsychotic Agents; Biogenic Monoamines; Brain; Female; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Neurotransmitter Agents; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Risperidone; Spiperone; Tissue Distribution | 1992 |
Stimulation by risperidone of rat prolactin secretion in vivo and in cultured pituitary cells in vitro.
Topics: Animals; Antipsychotic Agents; Cells, Cultured; Haloperidol; Isoxazoles; Ketanserin; Male; Piperidines; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Risperidone; Spiro Compounds; Stimulation, Chemical | 1992 |
Risperidone in the treatment of disorders with a combined psychotic and depressive syndrome--a functional approach.
Topics: Adult; Aged; Antipsychotic Agents; Depressive Disorder; Female; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Syndrome | 1992 |
Functional interaction between serotonin-S2 and dopamine-D2 neurotransmission as revealed by selective antagonism of hyper-reactivity to tryptamine and apomorphine.
Topics: Animals; Antipsychotic Agents; Apomorphine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Injections, Intravenous; Isoxazoles; Male; Piperidines; Rats; Rats, Inbred Strains; Risperidone; Ritanserin; Seizures; Serotonin; Serotonin Antagonists; Synaptic Transmission; Tryptamines | 1990 |
[Study by the intracerebral microdialysis method of the effects of atypical neuroleptics and anxiolytics on striatal release and metabolism of dopamine in awake rats].
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Brain Chemistry; Buspirone; Corpus Striatum; Dialysis; Dopamine; In Vitro Techniques; Isoxazoles; Male; Methoxydimethyltryptamines; Piperidines; Rats; Rats, Inbred Strains; Risperidone; Ritanserin; Sulpiride; Wakefulness | 1991 |
Efficacy and tolerability of a new antipsychotic compound (risperidone): results of a pilot study.
Topics: Acute Disease; Adult; Antipsychotic Agents; Chronic Disease; Female; Humans; Isoxazoles; Male; Middle Aged; Pilot Projects; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia | 1991 |
Pharmacology of risperidone (R 64 766), a new antipsychotic with serotonin-S2 and dopamine-D2 antagonistic properties.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Conditioning, Psychological; Dogs; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Isoxazoles; Male; Motor Activity; Oxazoles; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Risperidone; Serotonin Antagonists | 1988 |
Biochemical profile of risperidone, a new antipsychotic.
Topics: Animals; Antipsychotic Agents; Blood Platelets; Cerebral Cortex; Dopamine; Ergolines; Female; Haloperidol; Isoxazoles; Models, Molecular; Norepinephrine; Oxazoles; Phosphatidic Acids; Piperidines; Quinpirole; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Ritanserin; X-Ray Diffraction | 1988 |
Differential effects of the new antipsychotic risperidone on large and small motor movements in rats: a comparison with haloperidol.
Topics: Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Haloperidol; Isoxazoles; Male; Motor Activity; Oxazoles; Piperidines; Rats; Rats, Inbred Strains; Risperidone | 1988 |
Risperidone (R 64 766), a potent and complete LSD antagonist in drug discrimination by rats.
Topics: Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Stimulus; Isoxazoles; Lysergic Acid Diethylamide; Male; Oxazoles; Piperidines; Rats; Rats, Inbred Strains; Risperidone | 1989 |
Therapeutic effect and safety of increasing doses of risperidone (R 64766) in psychotic patients.
Topics: Adult; Aged; Antipsychotic Agents; Blood Pressure; Electrocardiography; Female; Hormones; Humans; Isoxazoles; Male; Middle Aged; Oxazoles; Piperidines; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone | 1989 |
Receptor occupancy by ritanserin and risperidone measured using ex vivo autoradiography.
Topics: Animals; Brain; Dopamine Antagonists; Isoxazoles; Male; Oxazoles; Piperidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Ritanserin; Serotonin Antagonists | 1989 |
Differential effects of the new antipsychotic risperidone on sleep and wakefulness in the rat.
Topics: Animals; Antipsychotic Agents; Isoxazoles; Male; Oxazoles; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Sleep; Wakefulness | 1989 |
Adverse reaction reporting and new antipsychotics.
Topics: Agranulocytosis; Anemia, Aplastic; Antipsychotic Agents; Clozapine; Drug Monitoring; Humans; Isoxazoles; Neutropenia; Piperidines; Remoxipride; Risperidone; Schizophrenia | 1993 |
Dopamine D2 receptor occupancy in vivo and response to the new antipsychotic risperidone.
Topics: Adult; Antipsychotic Agents; Benzamides; Brain; Brain Mapping; Contrast Media; Dopamine D2 Receptor Antagonists; Humans; Iodine Radioisotopes; Isoxazoles; Male; Piperidines; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon | 1993 |
Risperidone and remoxipride for schizophrenia.
Topics: Antipsychotic Agents; Female; Humans; Isoxazoles; Piperidines; Remoxipride; Risperidone; Schizophrenia | 1993 |
5-HT2 receptor antagonists do not reduce ethanol preference in Sardinian alcohol-preferring (sP) rats.
Topics: Alcohol Drinking; Animals; Antipsychotic Agents; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Risperidone; Ritanserin; Serotonin Antagonists | 1993 |
Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography.
Topics: Animals; Antipsychotic Agents; Apomorphine; Autoradiography; Behavior, Animal; Clozapine; Guinea Pigs; Haloperidol; In Vitro Techniques; Iodine Radioisotopes; Isoxazoles; Male; Mescaline; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Neurotransmitter; Receptors, Serotonin; Risperidone; Stereotyped Behavior | 1993 |
Risperidone for chronic schizophrenia.
Topics: Antipsychotic Agents; Chronic Disease; Clinical Trials as Topic; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
Pharmacological action of zotepine and other antipsychotics on central 5-hydroxytryptamine receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Body Temperature; Clozapine; Dibenzothiepins; Exploratory Behavior; Haloperidol; Isoxazoles; Male; Mice; Motor Activity; Piperazines; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists | 1994 |
Serotonin2 receptor-mediated excitation of interneurons in piriform cortex: antagonism by atypical antipsychotic drugs.
Topics: Action Potentials; Animals; Antipsychotic Agents; Bicuculline; Cerebral Cortex; Chlorpromazine; Clozapine; Electrophysiology; gamma-Aminobutyric Acid; Haloperidol; In Vitro Techniques; Interneurons; Isoxazoles; Male; Membrane Potentials; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin Antagonists | 1994 |
Risperidone for hallucinations in levodopa-treated Parkinson's disease patients.
Topics: Aged; Antipsychotic Agents; Hallucinations; Humans; Isoxazoles; Levodopa; Parkinson Disease; Piperidines; Risperidone | 1994 |
Risperidone.
Topics: Adult; Clinical Trials as Topic; Humans; Isoxazoles; Multicenter Studies as Topic; Piperidines; Placebos; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1994 |
Is it possible to predict the clinical effects of neuroleptics from animal data? Part V: From haloperidol and pipamperone to risperidone.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Butyrophenones; Dogs; Dopamine D2 Receptor Antagonists; Haloperidol; Humans; In Vitro Techniques; Isoxazoles; Lysergic Acid Diethylamide; Motor Activity; Neostriatum; Oxygen Consumption; Piperidines; Rats; Risperidone; Schizophrenia; Serotonin Antagonists; Species Specificity; Tryptamines | 1994 |
In vivo dopamine-D2 and serotonin-5-HT2 receptor binding study of risperidone and haloperidol.
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Cerebellum; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Haloperidol; In Vitro Techniques; Isoxazoles; Ketanserin; Ligands; Male; Neostriatum; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone | 1994 |
Schizophrenia.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
Risperidone for schizophrenia.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
Dystonic reaction and relapse with clozapine discontinuation and risperidone intiation.
Topics: Adult; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Dystonia; Humans; Isoxazoles; Male; Neurologic Examination; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Substance Withdrawal Syndrome | 1994 |
New antipsychotic agent, risperidone, introduced.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Piperidines; Psychotic Disorders; Risperidone | 1994 |
Risperidone-induced priapism.
Topics: Antipsychotic Agents; Chronic Disease; Drug Therapy, Combination; Humans; Isoxazoles; Lithium Carbonate; Lorazepam; Male; Middle Aged; Piperidines; Priapism; Risperidone; Schizophrenia, Paranoid | 1994 |
Risperidone: a novel antipsychotic medication.
Topics: Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Approval; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
New drug offers hope for people with schizophrenia.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
The effect of risperidone and ritanserin on human IgG and IgM synthesis in vitro.
Topics: Antipsychotic Agents; B-Lymphocytes; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Immunoglobulin M; In Vitro Techniques; Isoxazoles; Monocytes; Piperidines; Pokeweed Mitogens; Risperidone; Ritanserin; Schizophrenia | 1994 |
Antidepressant activity and mania associated with risperidone treatment of schizoaffective disorder.
Topics: Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Humans; Isoxazoles; Piperidines; Risperidone | 1994 |
Response to clozapine as a predictor of risperidone response in schizophrenia.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Humans; Isoxazoles; Piperidines; Receptors, Dopamine; Risperidone; Schizophrenia; Treatment Outcome | 1994 |
The pharmacokinetics of risperidone in humans: a summary.
Topics: Aged; Animals; Antipsychotic Agents; Biotransformation; Dogs; Half-Life; Humans; Isoxazoles; Liver Cirrhosis; Male; Paliperidone Palmitate; Piperidines; Pyrimidines; Rats; Reference Values; Renal Insufficiency; Risperidone; Schizophrenia | 1994 |
Risperidone: new horizons for the schizophrenic patient. 9th World Congress of Psychiatry of the World Psychiatric Association, Rio de Janeiro, June 1993.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity.
Topics: Animals; Antipsychotic Agents; Brain; Clone Cells; Clozapine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Guinea Pigs; Haloperidol; Humans; Isoxazoles; Paliperidone Palmitate; Piperidines; Pyrimidines; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Serotonin Antagonists | 1994 |
Risperidone in Parkinson's disease.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Parkinson Disease; Piperidines; Psychotic Disorders; Risperidone | 1994 |
Risperidone in HIV-related manic psychosis.
Topics: AIDS Dementia Complex; Antipsychotic Agents; Bipolar Disorder; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone | 1994 |
Risperidone-induced neuroleptic malignant syndrome.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Female; Humans; Isoxazoles; Male; Neuroleptic Malignant Syndrome; Piperidines; Risperidone | 1994 |
Risperidone, serotonergic mechanisms, and obsessive-compulsive symptoms in schizophrenia.
Topics: Adult; Antipsychotic Agents; Drug Therapy, Combination; Fluvoxamine; Humans; Isoxazoles; Male; Obsessive-Compulsive Disorder; Piperidines; Receptors, Serotonin; Risperidone; Schizophrenia; Schizophrenic Psychology; Serotonin | 1994 |
FDA approved new drug bulletin: risperidone (risperdal).
Topics: Adult; Antipsychotic Agents; Child; Drug Interactions; Female; Humans; Isoxazoles; Patient Education as Topic; Piperidines; Pregnancy; Risperidone | 1994 |
Risperidone in adolescents.
Topics: Adolescent; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hospitalization; Humans; Isoxazoles; Male; Piperidines; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Risperidone for Tourette's syndrome.
Topics: Adult; Antipsychotic Agents; Humans; Isoxazoles; Male; Piperidines; Risperidone; Severity of Illness Index; Tourette Syndrome | 1994 |
Risperidone treatment for severe negative symptoms.
Topics: Adult; Antipsychotic Agents; Clonazepam; Depressive Disorder; Drug Therapy, Combination; Humans; Isoxazoles; Male; Patient Readmission; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Risperidone in the treatment of pervasive developmental disorder.
Topics: Adolescent; Adult; Antipsychotic Agents; Autistic Disorder; Child; Child Development Disorders, Pervasive; Follow-Up Studies; Humans; Intellectual Disability; Isoxazoles; Male; Neuropsychological Tests; Piperidines; Risperidone; Serotonin; Stereotyped Behavior | 1994 |
Risperidone's cost.
Topics: Antipsychotic Agents; Delivery of Health Care; Health Services Accessibility; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
Risperidone-induced neuroleptic malignant syndrome in young patient.
Topics: Adult; Antipsychotic Agents; Haloperidol; Humans; Isoxazoles; Male; Neuroleptic Malignant Syndrome; Piperidines; Risperidone | 1994 |
Cortical response to exogenous visual stimulation during visual hallucinations.
Topics: Aged; Antipsychotic Agents; Dementia; Evoked Potentials, Visual; Hallucinations; Humans; Isoxazoles; Magnetic Resonance Imaging; Male; Piperidines; Risperidone; Visual Cortex | 1995 |
High-dose antipsychotic medication.
Topics: Adult; Ambulatory Care; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Risperidone and obsessive-compulsive symptoms.
Topics: Antipsychotic Agents; Bipolar Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Isoxazoles; Lithium Carbonate; Male; Middle Aged; Neurologic Examination; Obsessive-Compulsive Disorder; Pimozide; Piperidines; Recurrence; Risperidone | 1994 |
Blockade of the discriminative stimulus effects of DOI by MDL 100,907 and the 'atypical' antipsychotics, clozapine and risperidone.
Topics: Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Fluorobenzenes; Isoxazoles; Male; Motor Activity; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone; Serotonin Antagonists | 1994 |
Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors.
Topics: Animals; Antipsychotic Agents; Autoradiography; Clozapine; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Neurotransmitter; Receptors, Serotonin; Risperidone | 1993 |
Risperidone.
Topics: Adolescent; Adult; Antipsychotic Agents; Community Mental Health Services; Humans; Isoxazoles; Mental Disorders; Piperidines; Risperidone | 1994 |
Serotonin-dopamine antagonist and Gilles de la Tourette's syndrome: an open pilot dose-titration study with risperidone.
Topics: Adult; Antipsychotic Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Isoxazoles; Male; Middle Aged; Neurologic Examination; Pilot Projects; Piperidines; Risperidone; Serotonin Antagonists; Tourette Syndrome | 1994 |
Regional brain distribution of risperidone and its active metabolite 9-hydroxy-risperidone in the rat.
Topics: Animals; Antiemetics; Antipsychotic Agents; Apomorphine; Brain; Dogs; Half-Life; Injections, Subcutaneous; Isoxazoles; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Organ Size; Paliperidone Palmitate; Piperidines; Pyrimidines; Rats; Rats, Wistar; Receptors, Neurotransmitter; Risperidone; Spectrophotometry, Ultraviolet; Tryptamines | 1994 |
Effects of typical and atypical antipsychotic drugs on response decrement patterns in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Conditioning, Operant; Dose-Response Relationship, Drug; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Remoxipride; Risperidone; Serotonin Antagonists; Sulpiride | 1995 |
Agitated behavior relieved following treatment of cervical dystonia in dementia.
Topics: Alzheimer Disease; Botulinum Toxins; Chlorpromazine; Dystonia; Female; Humans; Isoxazoles; Middle Aged; Neck Muscles; Phenytoin; Piperidines; Risperidone; Valproic Acid | 1995 |
Plasma protein binding of risperidone and its distribution in blood.
Topics: Adult; Aged; Animals; Antipsychotic Agents; Blood Cells; Blood Proteins; Dogs; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Isoxazoles; Kidney Diseases; Liver Diseases; Male; Middle Aged; Orosomucoid; Paliperidone Palmitate; Piperidines; Protein Binding; Pyrimidines; Rats; Rats, Wistar; Risperidone; Serum Albumin | 1994 |
Effects of risperidone on phencyclidine-induced behaviors: comparison with haloperidol and ritanserin.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Frontal Lobe; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Isoxazoles; Locomotion; Male; Phencyclidine; Piperidines; Random Allocation; Rats; Rats, Wistar; Risperidone; Ritanserin; Schizophrenia; Serotonin; Stereotyped Behavior | 1994 |
Risperidone prevents the development of supersensitivity, but not tolerance, to phencyclidine in rats treated with subacute phencyclidine.
Topics: Animals; Antipsychotic Agents; Dizocilpine Maleate; Drug Tolerance; Haloperidol; Isoxazoles; Male; Methamphetamine; Motor Activity; Phencyclidine; Piperidines; Rats; Rats, Wistar; Receptors, Phencyclidine; Receptors, Serotonin; Risperidone; Ritanserin | 1995 |
Novel neuroleptics in schizophrenia: theory and clinical relevance.
Topics: Antipsychotic Agents; Brain; Clozapine; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Re: Hypomania associated with risperidone.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Chronic Disease; Female; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia, Paranoid | 1995 |
Schizophrenia and severe tardive dyskinesia responsive to risperidone.
Topics: Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Isoxazoles; Neurologic Examination; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Addressing emerging social needs of patients treated with new neuroleptics.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Humans; Isoxazoles; Male; Middle Aged; Nursing Assessment; Piperidines; Psychiatric Nursing; Risperidone; Schizophrenia; Socialization | 1994 |
Positron emission tomography studies on D2 and 5-HT2 receptor binding in risperidone-treated schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Binding Sites; Brain; Female; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia; Tomography, Emission-Computed | 1995 |
Risperidone in Parkinson's disease.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Parkinson Disease; Piperidines; Risperidone | 1995 |
Recent developments in antipsychotic therapy. Introduction.
Topics: Antipsychotic Agents; Clozapine; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1995 |
Risperidone in childhood schizophrenia.
Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child; Drug Therapy, Combination; Humans; Isoxazoles; Male; Methylphenidate; Piperidines; Risperidone; Schizophrenia; Treatment Outcome | 1995 |
Effects of concomitant risperidone and lithium treatment.
Topics: Antipsychotic Agents; Confusion; Creatine Kinase; Drug Therapy, Combination; Fever; Humans; Isoxazoles; Lithium Carbonate; Neuroleptic Malignant Syndrome; Piperidines; Risperidone; Schizophrenia | 1995 |
Behavioral stimulation associated with risperidone initiation.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Anxiety; Benzodiazepines; Confusion; Female; Humans; Isoxazoles; Middle Aged; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome | 1995 |
Prolonged erection associated with risperidone treatment.
Topics: Adult; Antipsychotic Agents; Humans; Isoxazoles; Male; Piperidines; Priapism; Psychotic Disorders; Risperidone | 1995 |
Risperidone treatment for a Tourette's disorder patient with comorbid obsessive-compulsive disorder.
Topics: Adult; Antipsychotic Agents; Comorbidity; Depressive Disorder; Drug Therapy, Combination; Fluoxetine; Humans; Isoxazoles; Male; Obsessive-Compulsive Disorder; Piperidines; Risperidone; Tourette Syndrome; Treatment Outcome | 1995 |
Switching patients from clozapine to risperidone therapy.
Topics: Antipsychotic Agents; Clonazepam; Clozapine; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoxazoles; Lorazepam; Piperidines; Risperidone; Schizophrenia; Substance Withdrawal Syndrome | 1995 |
Risperidone-induced prolactin elevations in premenopausal women with schizophrenia.
Topics: Antipsychotic Agents; Female; Humans; Hyperprolactinemia; Isoxazoles; Piperidines; Premenopause; Prolactin; Risperidone; Schizophrenia | 1995 |
Prescribing risperidone.
Topics: Antipsychotic Agents; Cost-Benefit Analysis; Drug Prescriptions; Financing, Government; Health Care Rationing; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Virginia | 1995 |
Risperidone for psychotic and behavioural symptoms in Lewy body dementia.
Topics: Aged; Antipsychotic Agents; Dementia; Female; Humans; Isoxazoles; Male; Piperidines; Risperidone | 1995 |
Risperidone for the treatment of schizophrenia: does it have a niche?
Topics: Dopamine Antagonists; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
Reversible neutropenia during a cold: possible involvement of risperidone? A case report.
Topics: Adult; Antipsychotic Agents; Cold Temperature; Female; Humans; Influenza, Human; Isoxazoles; Neutropenia; Piperidines; Risperidone; Schizophrenia | 1995 |
Effect of clozapine and risperidone on 5-HT2 and D2-dopamine receptor binding in the post-mortem human brain. An autoradiographic study.
Topics: Adult; Antipsychotic Agents; Autopsy; Autoradiography; Binding Sites; Brain; Clozapine; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone | 1995 |
Risperidone in Gilles de la Tourette syndrome.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Tourette Syndrome | 1995 |
Risperidone augmentation of clozapine.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Isoxazoles; Male; Piperidines; Psychotic Disorders; Risperidone; Schizophrenia, Paranoid; Schizophrenic Psychology | 1995 |
Risperidone for treatment-refractory schizophrenia.
Topics: Adult; Antipsychotic Agents; Humans; Isoxazoles; Male; Piperidines; Risperidone; Schizophrenia; Treatment Outcome | 1995 |
Two cases of risperidone-induced neuroleptic malignant syndrome.
Topics: Adult; Antipsychotic Agents; Female; Humans; Isoxazoles; Neuroleptic Malignant Syndrome; Piperidines; Primidone; Psychotic Disorders; Risperidone; Tremor | 1995 |
Two cases of risperidone-induced neuroleptic malignant syndrome.
Topics: Aged; Antipsychotic Agents; Humans; Isoxazoles; Male; Neuroleptic Malignant Syndrome; Piperidines; Risperidone; Schizophrenia, Paranoid | 1995 |
Use of risperidone with a patient sensitive to conventional neuroleptic drugs.
Topics: Antipsychotic Agents; Bipolar Disorder; Humans; Isoxazoles; Male; Middle Aged; Neuroleptic Malignant Syndrome; Piperidines; Risperidone; Treatment Outcome | 1995 |
Risperidone for treating dementia-associated aggression.
Topics: Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Dementia; Dementia, Vascular; Female; Humans; Isoxazoles; Male; Piperidines; Psychotropic Drugs; Risperidone; Treatment Outcome | 1995 |
Clinical implications of clozapine discontinuation: report of an NIMH workshop.
Topics: Antipsychotic Agents; Clozapine; Drug Administration Schedule; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Substance Withdrawal Syndrome; United States; United States Food and Drug Administration | 1995 |
Unexpected dystonia while changing from clozapine to risperidone.
Topics: Adult; Antipsychotic Agents; Clozapine; Dystonia; Humans; Isoxazoles; Male; Piperidines; Risperidone; Schizophrenia | 1995 |
Concomitant use of thioridazine with risperidone.
Topics: Antipsychotic Agents; Drug Therapy, Combination; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia; Thioridazine | 1995 |
The D2 dopamine receptor occupancy of risperidone and its relationship to extrapyramidal symptoms: a PET study.
Topics: Adult; Akathisia, Drug-Induced; Basal Ganglia Diseases; Humans; Isoxazoles; Male; Piperidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed | 1995 |
Clinical experience with risperidone.
Topics: Adolescent; Aggression; Antipsychotic Agents; Bipolar Disorder; Child; Child Behavior Disorders; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Isoxazoles; Lithium; Male; Piperidines; Risperidone | 1995 |
Is risperidone a substitute for clozapine for patients who do not respond to neuroleptics?
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Piperidines; Recurrence; Risperidone; Schizophrenia; Schizophrenia, Paranoid | 1995 |
Pharmacokinetic interaction between risperidone and clozapine.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Interactions; Drug Therapy, Combination; Humans; Isoxazoles; Male; Piperidines; Psychotic Disorders; Risperidone | 1995 |
Neuroleptic sensitivity to risperidone in Lewy body dementia.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Basal Ganglia Diseases; Dementia; Female; Humans; Isoxazoles; Lewy Bodies; Male; Middle Aged; Parkinson Disease; Piperidines; Risperidone | 1995 |
Olanzapine, an atypical antipsychotic, increases rates of punished responding in pigeons.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Chlordiazepoxide; Clozapine; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Haloperidol; Isoxazoles; Male; Olanzapine; Piperidines; Pirenzepine; Punishment; Risperidone | 1995 |
Risperidone treatment of refractory acute mania.
Topics: Acute Disease; Adult; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Isoxazoles; Male; Piperidines; Risperidone; Treatment Outcome | 1995 |
The pharmacological profile of iloperidone, a novel atypical antipsychotic agent.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Basal Ganglia Diseases; Behavior, Animal; Clozapine; Dopamine Antagonists; Haloperidol; Isoxazoles; Male; Mice; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Risperidone; Saimiri; Serotonin Antagonists | 1995 |
Suppression of alcohol preference in rats induced by risperidone, a serotonin 5-HT2 and dopamine D2 receptor antagonist.
Topics: Alcohol Drinking; Animals; Antipsychotic Agents; Dopamine D2 Receptor Antagonists; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Risperidone; Serotonin Antagonists | 1993 |
Dopamine D1, D2 and serotonin2 receptor occupation by typical and atypical antipsychotic drugs in vivo.
Topics: Animals; Antipsychotic Agents; Dopamine D2 Receptor Antagonists; Haloperidol; Isoxazoles; Male; Piperidines; Quinolines; Rats; Rats, Wistar; Receptors, Dopamine D1; Risperidone; Serotonin Antagonists | 1993 |
[Clinical evaluation of risperidone].
Topics: Antipsychotic Agents; Humans; Isoxazoles; Piperidines; Psychotic Disorders; Risperidone | 1993 |
Neuroleptics and the immune system.
Topics: Adult; Antipsychotic Agents; Female; Humans; Immunity; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone | 1993 |
Effects of atypical antipsychotic agents on social behavior in rodents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Catalepsy; Chlorpromazine; Clozapine; Diazepam; Haloperidol; Isoxazoles; Male; Mice; Mice, Inbred Strains; Piperidines; Raclopride; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Social Behavior | 1993 |
Determination of risperidone and 9-hydroxyrisperidone in human plasma by high-performance liquid chromatography with electrochemical detection.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Isoxazoles; Paliperidone Palmitate; Piperidines; Pyrimidines; Regression Analysis; Risperidone | 1993 |
[Effects of risperidone on catalepsy and cerebral dopamine, serotonin and GABA metabolism in the rat: comparison with haloperidol].
Topics: Animals; Antipsychotic Agents; Brain; Catalepsy; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Risperidone; Serotonin | 1993 |
[A study on the pharmacological properties of atypical antipsychotic drugs: in vivo dopamine and serotonin receptor occupancy by atypical antipsychotic drugs in the rat brain].
Topics: Animals; Antipsychotic Agents; Autoradiography; Brain; Chlorpromazine; Clozapine; Dibenzothiepins; Flupenthixol; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Piperidines; Pyrimidinones; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone | 1993 |
Clozapine in the management of schizophrenia. Risperidone is less toxic but equally effective.
Topics: Antipsychotic Agents; Clozapine; Drug Costs; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1993 |
Determination of risperidone in plasma by high-performance liquid chromatography with electrochemical detection: application to therapeutic drug monitoring in schizophrenic patients.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Isoxazoles; Piperidines; Remoxipride; Risperidone; Schizophrenia | 1993 |
Biphasic displacement of [3H]YM-09151-2 binding in the rat brain by thioridazine, risperidone and clozapine, but not by other antipsychotics.
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Clozapine; Corpus Striatum; Dopamine D2 Receptor Antagonists; In Vitro Techniques; Isoxazoles; Male; Olfactory Pathways; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Risperidone; Spiperone; Thioridazine | 1993 |
Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects.
Topics: Adult; Antipsychotic Agents; Biological Availability; Humans; Isoxazoles; Male; Models, Biological; Piperidines; Prolactin; Random Allocation; Reference Values; Risperidone | 1993 |
Pharmacological effects of zotepine and other antipsychotics on the central 5-HT2 receptors.
Topics: Animals; Antipsychotic Agents; Clozapine; Dibenzothiepins; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone | 1993 |
Binding of antipsychotic drugs at alpha 1A- and alpha 1B-adrenoceptors: risperidone is selective for the alpha 1B-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Binding Sites; Dioxanes; Hippocampus; In Vitro Techniques; Isoxazoles; Male; Phentolamine; Piperazines; Piperidines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Risperidone; Spleen | 1993 |
Overdose of risperidone.
Topics: Adult; Antipsychotic Agents; Electrocardiography; Humans; Isoxazoles; Male; Piperidines; Poisoning; Risperidone; Suicide, Attempted | 1993 |
Therapeutic drug monitoring of risperidone and 9-hydroxyrisperidone in serum with solid-phase extraction and high-performance liquid chromatography.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Risperidone | 1997 |
Simplified high-performance liquid chromatographic method for determination of risperidone and 9-hydroxyrisperidone in serum from patients comedicated with other psychotropic drugs.
Topics: Antipsychotic Agents; Artifacts; Chromatography, High Pressure Liquid; Haloperidol; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Reproducibility of Results; Risperidone; Spectrophotometry, Ultraviolet | 1997 |
Distribution after repeated oral administration of different dose levels of risperidone and 9-hydroxy-risperidone in the brain and other tissues of rat.
Topics: Animals; Antipsychotic Agents; Brain; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone; Tissue Distribution | 1998 |
Metabolism of risperidone to 9-hydroxyrisperidone by human cytochromes P450 2D6 and 3A4.
Topics: Animals; Antipsychotic Agents; Biotransformation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Isoenzymes; Isoxazoles; Microsomes, Liver; Mixed Function Oxygenases; Paliperidone Palmitate; Pyrimidines; Rats; Recombinant Proteins; Risperidone | 1999 |
Effect of venlafaxine on the pharmacokinetics of risperidone.
Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Anxiety; Area Under Curve; Cyclohexanols; Desvenlafaxine Succinate; Exploratory Behavior; Female; Humans; Isoxazoles; Male; Metabolic Clearance Rate; Middle Aged; Paliperidone Palmitate; Psychomotor Performance; Pyrimidines; Risperidone; Venlafaxine Hydrochloride | 1999 |
Pharmacokinetic-pharmacodynamic modeling of risperidone effects on electroencephalography in healthy volunteers.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Electroencephalography; Humans; Isoxazoles; Male; Models, Biological; Paliperidone Palmitate; Pyrimidines; Risperidone | 1999 |
A pilot study on risperidone metabolism: the role of cytochromes P450 2D6 and 3A.
Topics: Adolescent; Adult; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Case-Control Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Genotype; Humans; Isoxazoles; Male; Mental Disorders; Middle Aged; Oxidoreductases, N-Demethylating; Paliperidone Palmitate; Pilot Projects; Pyrimidines; Risperidone | 1999 |
Simultaneous determination of paroxetine, risperidone and 9-hydroxyrisperidone in human plasma by high-performance liquid chromatography with coulometric detection.
Topics: Chromatography, High Pressure Liquid; Colorimetry; Drug Monitoring; Humans; Isoxazoles; Paliperidone Palmitate; Paroxetine; Pyrimidines; Risperidone; Spectrophotometry, Ultraviolet | 2000 |
Risperidone distribution and excretion into human milk: case report and estimated infant exposure during breast-feeding.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Breast Feeding; Female; Humans; Infant, Newborn; Isoxazoles; Milk, Human; Paliperidone Palmitate; Pregnancy; Pyrimidines; Risperidone | 2000 |
Identification of the major human liver cytochrome P450 isoform(s) responsible for the formation of the primary metabolites of ziprasidone and prediction of possible drug interactions.
Topics: Antipsychotic Agents; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoenzymes; Isoxazoles; Liver; Microsomes, Liver; Paliperidone Palmitate; Piperazines; Pyrimidines; Risperidone; Sulfones; Sulfoxides; Thiazoles | 2000 |
Simultaneous determination of risperidone and 9-hydroxyrisperidone in plasma by liquid chromatography/electrospray tandem mass spectrometry.
Topics: Animals; Antipsychotic Agents; Chromatography, Liquid; Humans; Isoxazoles; Mass Spectrometry; Paliperidone Palmitate; Pyrimidines; Rats; Risperidone; Schizophrenia; Sensitivity and Specificity | 2000 |
Plasma concentrations of risperidone and 9-hydroxyrisperidone: effect of comedication with carbamazepine or valproate.
Topics: Adult; Antipsychotic Agents; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Isoxazoles; Male; Middle Aged; Mixed Function Oxygenases; Paliperidone Palmitate; Pyrimidines; Risperidone; Valproic Acid | 2000 |
Risperidone metabolism and the impact of being a cytochrome P450 2D6 ultrarapid metabolizer.
Topics: Adolescent; Adult; Cytochrome P-450 CYP2D6; Drug Monitoring; Genotype; Humans; Isoxazoles; Male; Paliperidone Palmitate; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyrimidines; Risperidone | 2000 |
Determination of risperidone and its major metabolite 9-hydroxyrisperidone in human plasma by reversed-phase liquid chromatography with ultraviolet detection.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Reproducibility of Results; Risperidone; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2000 |
Plasma concentrations of risperidone and 9-hydroxyrisperidone during combined treatment with paroxetine.
Topics: Adult; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Drug Interactions; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Paroxetine; Pyrimidines; Risperidone; Selective Serotonin Reuptake Inhibitors | 2001 |
Possible relationship between combined plasma concentrations of risperidone plus 9-hydroxyrisperidone and extrapyramidal symptoms. Preliminary study.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia | 2001 |
Brain, plasma and tissue pharmacokinetics of risperidone and 9-hydroxyrisperidone after separate oral administration to rats.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Brain; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin Antagonists; Tissue Distribution | 2002 |
In vivo and in vitro myocardial binding of risperidone and 9-hydroxyrisperidone.
Topics: Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Guinea Pigs; Isoxazoles; Myocardium; Paliperidone Palmitate; Pyrimidines; Risperidone | 2002 |
Simplified high-performance liquid chromatographic method for determination of risperidone and 9-hydroxyrisperidone in plasma after overdose.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Drug Overdose; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Reproducibility of Results; Risperidone; Sensitivity and Specificity | 2002 |
Risperidone and 9-hydroxyrisperidone concentrations are not dependent on age or creatinine clearance among elderly subjects.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Antipsychotic Agents; Creatinine; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Radioimmunoassay; Risperidone | 2002 |
Prediction and assessment of extrapyramidal side effects induced by risperidone based on dopamine D(2) receptor occupancy.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Dopamine Antagonists; Humans; Isoxazoles; Models, Biological; Paliperidone Palmitate; Pyrimidines; Receptors, Dopamine D2; Risperidone | 2002 |
A colloidal graphite-coated emitter for sheathless capillary electrophoresis/nanoelectrospray ionization mass spectrometry.
Topics: Colloids; Electrophoresis, Capillary; Graphite; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Risperidone; Spectrometry, Mass, Electrospray Ionization | 2002 |
Determination of risperidone and 9-hydroxyrisperidone in human plasma by liquid chromatography: application to the evaluation of CYP2D6 drug interactions.
Topics: Adult; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Drug Interactions; Humans; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Reproducibility of Results; Risperidone | 2003 |
Validated method for the determination of risperidone and 9-hydroxyrisperidone in human plasma by liquid chromatography-tandem mass spectrometry.
Topics: Antipsychotic Agents; Chromatography, Liquid; Humans; Isoxazoles; Mass Spectrometry; Paliperidone Palmitate; Pyrimidines; Risperidone | 2003 |
Relationship between risperidone and 9-hydroxy-risperidone plasma concentrations and CYP2D6 enzyme activity in psychiatric patients.
Topics: Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Genotype; Humans; Isoxazoles; Middle Aged; Paliperidone Palmitate; Phenotype; Pyrimidines; Risperidone; Schizophrenia; White People | 2002 |
[Determination of risperidone and 9-hydroxyrisperidone in plasma by high performance liquid chromatography].
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Risperidone; Serotonin Antagonists | 1999 |
alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brimonidine Tartrate; Chlorpromazine; CHO Cells; Clozapine; Cricetinae; Cyclic AMP; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Gene Expression; Haloperidol; Humans; Isoxazoles; Norepinephrine; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Quinolones; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Risperidone; Thiazoles; Transfection; Yohimbine | 2003 |
Effects of CYP2D6 genotypes on plasma concentrations of risperidone and enantiomers of 9-hydroxyrisperidone in Japanese patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Female; Genotype; Half-Life; Humans; Hydroxylation; Isoxazoles; Japan; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia; Stereoisomerism | 2003 |
Effects of various CYP2D6 genotypes on the steady-state plasma concentrations of risperidone and its active metabolite, 9-hydroxyrisperidone, in Japanese patients with schizophrenia.
Topics: Adult; Analysis of Variance; Cytochrome P-450 CYP2D6; Female; Genotype; Humans; Isoxazoles; Japan; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia | 2003 |
Intra- and interindividual variations in steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients treated chronically with various doses of risperidone.
Topics: Adult; Antipsychotic Agents; Drug Monitoring; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Risperidone | 2003 |
Transfer of risperidone and 9-hydroxyrisperidone into human milk.
Topics: Adult; Area Under Curve; Breast Feeding; Depression, Postpartum; Female; Galactorrhea; Humans; Infant; Isoxazoles; Male; Milk, Human; Paliperidone Palmitate; Pyrimidines; Risperidone | 2004 |
Quantification of risperidone and 9-hydroxyrisperidone in plasma and saliva from adult and pediatric patients by liquid chromatography-mass spectrometry.
Topics: Adult; Calibration; Chemical Precipitation; Child; Chromatography, Liquid; Humans; Isoxazoles; Mass Spectrometry; Molecular Structure; Paliperidone Palmitate; Pyrimidines; Reproducibility of Results; Risperidone; Saliva; Sensitivity and Specificity | 2004 |
Effects of various factors on steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: lack of impact of MDR-1 genotypes.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Female; Genes, MDR; Genotype; Humans; Isoxazoles; Male; Middle Aged; Mutation; Paliperidone Palmitate; Polymorphism, Genetic; Pyrimidines; Risperidone; Schizophrenia | 2004 |
QTc interval, CYP2D6 and CYP2C9 genotypes and risperidone plasma concentrations.
Topics: Administration, Oral; Adult; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Drug Administration Schedule; Electrocardiography; Genotype; Humans; Isoxazoles; Long QT Syndrome; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone | 2004 |
In vitro effects of risperidone and 9-hydroxy-risperidone on human platelet function, plasma coagulation, and fibrinolysis.
Topics: Adult; Animals; Aorta; Arachidonic Acid; Blood Coagulation Tests; Clonidine; Epinephrine; Ergotamine; Fibrinolysis; Humans; Isoxazoles; Male; Milrinone; Paliperidone Palmitate; Platelet Aggregation; Pyrimidines; Rats; Rats, Wistar; Reference Values; Risperidone; Serotonin; Serotonin Antagonists; Suprofen | 2004 |
A high-performance liquid chromatographic-atmospheric pressure chemical ionization-tandem mass spectrometric method for determination of risperidone and 9-hydroxyrisperidone in human plasma.
Topics: Antipsychotic Agents; Calibration; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Indicators and Reagents; Isoxazoles; Mass Spectrometry; Paliperidone Palmitate; Pyrimidines; Quality Control; Reference Standards; Reproducibility of Results; Risperidone | 2004 |
The brain entry of risperidone and 9-hydroxyrisperidone is greatly limited by P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Chromatography, High Pressure Liquid; Injections, Intraperitoneal; Isoxazoles; Male; Mice; Mice, Transgenic; Paliperidone Palmitate; Pyrimidines; Risperidone; Serotonin Antagonists; Tissue Distribution | 2004 |
Risperidone and breast-feeding.
Topics: Adult; Antipsychotic Agents; Breast Feeding; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Isoxazoles; Milk, Human; Paliperidone Palmitate; Postpartum Period; Psychotic Disorders; Pyrimidines; Risperidone | 2005 |
Prediction of response to risperidone treatment with respect to plasma concencentrations of risperidone, catecholamine metabolites, and polymorphism of cytochrome P450 2D6.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Caffeine; Catecholamines; Central Nervous System Stimulants; Cotinine; Cues; Cytochrome P-450 CYP2D6; Female; Homovanillic Acid; Humans; Isoxazoles; Male; Methoxyhydroxyphenylglycol; Middle Aged; Paliperidone Palmitate; Polymorphism, Genetic; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Smoking | 2005 |
Predominant role of the 9-hydroxy metabolite of risperidone in elevating blood prolactin levels.
Topics: Adolescent; Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hyperprolactinemia; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Prolactin; Psychotic Disorders; Pyrimidines; Risperidone | 2005 |
Influence of age and gender on risperidone plasma concentrations.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Antipsychotic Agents; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone; Sex Characteristics | 2005 |
Subtherapeutic risperidone serum concentrations in an adolescent during hemodialysis: a pharmacological puzzle.
Topics: Adolescent; Antipsychotic Agents; Drug Monitoring; Female; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Renal Dialysis; Risperidone; Tics | 2005 |
Plasma risperidone levels and clinical response in patients with first-episode psychosis.
Topics: Adult; Antipsychotic Agents; Asian People; Drug Monitoring; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Psychotic Disorders; Pyrimidines; Risperidone; Treatment Outcome | 2005 |
Intestinal uptake and biodistribution of novel polymeric micelles after oral administration.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Area Under Curve; Biological Availability; Biological Transport; Caco-2 Cells; Carbon Radioisotopes; Enterocytes; Humans; Injections, Intravenous; Intestinal Absorption; Isoxazoles; Kidney; Male; Metabolic Clearance Rate; Micelles; Mononuclear Phagocyte System; Paliperidone Palmitate; Polyesters; Polyethylene Glycols; Polymers; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone; Tissue Distribution | 2006 |
Multiple dose pharmacokinetics of risperidone and 9-hydroxyrisperidone in Chinese female patients with schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Area Under Curve; Asian People; China; Female; Humans; Isoxazoles; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia | 2006 |
A PET study evaluating dopamine D2 receptor occupancy for long-acting injectable risperidone.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Brain; Carbon Radioisotopes; Corpus Striatum; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Injections; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Positron-Emission Tomography; Prolactin; Psychotic Disorders; Pyrimidines; Raclopride; Receptors, Dopamine D2; Risperidone; Schizophrenia | 2006 |
Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation.
Topics: Animals; Anisoles; Antipsychotic Agents; Benzazepines; Butaclamol; Caspase Inhibitors; Cell Death; Cells, Cultured; Chlorpromazine; Clozapine; Domperidone; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Ginkgo biloba; Haloperidol; Hippocampus; Indans; Isoxazoles; Neurons; Neuroprotective Agents; Peptides; Piperidines; Plant Extracts; Propylamines; Raclopride; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Remoxipride; Risperidone; Sulpiride | 2006 |
Serum concentrations of risperidone and 9-OH risperidone following intramuscular injection of long-acting risperidone compared with oral risperidone medication.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antipsychotic Agents; Bipolar Disorder; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Injections, Intramuscular; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Psychotic Disorders; Pyrimidines; Risperidone; Schizophrenia; Treatment Outcome | 2006 |
Liquid chromatography/tandem mass spectrometry method for simultaneous determination of risperidone and its active metabolite 9-hydroxyrisperidone in human plasma.
Topics: Administration, Oral; Antipsychotic Agents; Chromatography, High Pressure Liquid; Humans; Isoxazoles; Male; Microchemistry; Paliperidone Palmitate; Pyrimidines; Reproducibility of Results; Risperidone; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2006 |
Positive modulation of glutamatergic receptors potentiates the suppressive effects of antipsychotics on conditioned avoidance responding in rats.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Clozapine; Conditioning, Psychological; Dioxoles; Drug Synergism; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperidines; Pyrimidines; Rats; Rats, Wistar; Receptors, AMPA; Risperidone; Serine; Stereoisomerism | 2006 |
Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein.
Topics: Animals; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzodiazepines; Chlorpromazine; Clozapine; Cyclosporins; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Flow Cytometry; Fluorescent Dyes; Haloperidol; Isoxazoles; Kidney; Liver; LLC-PK1 Cells; Olanzapine; Paliperidone Palmitate; Pyrimidines; Quetiapine Fumarate; Rhodamine 123; Risperidone; Swine; Transfection | 2006 |
Risperidone and paliperidone inhibit p-glycoprotein activity in vitro.
Topics: Animals; Animals, Newborn; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Epithelial Cells; Inhibitory Concentration 50; Isoxazoles; Paliperidone Palmitate; Protein Transport; Pyrimidines; Rats; Rhodamine 123; Risperidone; Swine; Time Factors | 2007 |
Polymorphisms of the ABCB1 gene are associated with the therapeutic response to risperidone in Chinese schizophrenia patients.
Topics: Adult; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; China; Female; Gene Frequency; Humans; Isoxazoles; Linkage Disequilibrium; Male; Organic Anion Transporters; Paliperidone Palmitate; Polymorphism, Genetic; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 2006 |
Prolactin elevation of the antipsychotic risperidone is predominantly related to its 9-hydroxy metabolite.
Topics: Adult; Antipsychotic Agents; Biotransformation; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Prolactin; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrimidines; Risperidone; Schizophrenia | 2006 |
Valproic acid improves psychotic agitation without influencing plasma risperidone levels in schizophrenic patients.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Drug Interactions; Female; Homovanillic Acid; Humans; Isoxazoles; Male; Methoxyhydroxyphenylglycol; Middle Aged; Paliperidone Palmitate; Psychiatric Status Rating Scales; Psychomotor Agitation; Pyrimidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Valproic Acid | 2007 |
Determination of risperidone and enantiomers of 9-hydroxyrisperidone in plasma by LC-MS/MS.
Topics: Child; Chromatography, Liquid; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Reference Standards; Reproducibility of Results; Risperidone; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry | 2007 |
Treatment with risperidone for 4 weeks increased plasma 3-methoxy-4-hydroxypnenylglycol (MHPG) levels, but did not alter plasma brain-derived neurotrophic factor (BDNF) levels in schizophrenic patients.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Catecholamines; Chromatography, High Pressure Liquid; Female; Genotype; Humans; Immunoenzyme Techniques; Isoxazoles; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine Plasma Membrane Transport Proteins; Paliperidone Palmitate; Polymorphism, Genetic; Pyrimidines; Risperidone; Schizophrenia | 2007 |
Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norepinephrine neurons.
Topics: Adrenergic Uptake Inhibitors; Animals; Antipsychotic Agents; Citalopram; Desipramine; Dose-Response Relationship, Drug; Electrophysiology; Infusion Pumps; Injections, Intravenous; Isoxazoles; Male; Neurons; Norepinephrine; Paliperidone Palmitate; Piperazines; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists | 2007 |
Limitations in discerning the effects of risperidone and its 9-hydroxy metabolite on prolactin levels in a small study of patients with schizophrenia.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Paliperidone Palmitate; Prolactin; Pyrimidines; Risperidone; Schizophrenia | 2007 |
Enantioselective analysis of the antipsychotic 9-hydroxyrisperidone, main metabolite of risperidone, by chiral capillary EKC using dual CDs.
Topics: beta-Cyclodextrins; Chromatography, Micellar Electrokinetic Capillary; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Risperidone; Stereoisomerism | 2007 |
Analytical and semipreparative enantioseparation of 9-hydroxyrisperidone, the main metabolite of risperidone, using high-performance liquid chromatography and capillary electrophoresis. Validation and determination of enantiomeric purity.
Topics: Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Isoxazoles; Molecular Structure; Paliperidone Palmitate; Pyrimidines; Reproducibility of Results; Risperidone; Stereoisomerism | 2007 |
[Development and identifiability analysis of parent-metabolite pharmacokinetic model for risperidone and its main active metabolite 9-hydroxyrisperidone].
Topics: Adult; Cytochrome P-450 CYP2D6; Humans; Isoxazoles; Male; Models, Biological; Monte Carlo Method; Paliperidone Palmitate; Pyrimidines; Risperidone | 2007 |
Serum prolactin levels, plasma risperidone levels, polymorphism of cytochrome P450 2D6 and clinical response in patients with schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Polymorphism, Genetic; Prolactin; Pyrimidines; Risperidone; Schizophrenia | 2007 |
Sensitive liquid chromatography/tandem mass spectrometry method for the simultaneous determination of olanzapine, risperidone, 9-hydroxyrisperidone, clozapine, haloperidol and ziprasidone in rat brain tissue.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chromatography, Liquid; Clozapine; Haloperidol; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperazines; Pyrimidines; Rats; Reproducibility of Results; Risperidone; Tandem Mass Spectrometry; Thiazoles | 2007 |
Identification, isolation and characterization of potential degradation product in risperidone tablets.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Drug Contamination; Drug Stability; Hot Temperature; Isoxazoles; Light; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Molecular Structure; Risperidone; Tablets | 2008 |
Relationship between prolactin secretion, and plasma risperidone and 9-hydroxyrisperidone concentrations in adolescents with schizophreniform disorder.
Topics: Adolescent; Adolescent Medicine; Age Factors; Antipsychotic Agents; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Isoxazoles; Male; Paliperidone Palmitate; Prolactin; Psychotic Disorders; Pyrimidines; Risperidone | 2008 |
Paliperidone: new drug. Just a metabolite of risperidone, a neuroleptic soon off-patent.
Topics: Antipsychotic Agents; Delayed-Action Preparations; Dose-Response Relationship, Drug; Haloperidol; Humans; Isoxazoles; Pyrimidines; Risperidone; Schizophrenia; Treatment Outcome | 2007 |
Pharmacodynamic consequences of P-glycoprotein-dependent pharmacokinetics of risperidone and haloperidol in mice.
Topics: Animals; Antipsychotic Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Haloperidol; Isoxazoles; Male; Mice; Mice, Knockout; Motor Activity; Paliperidone Palmitate; Pyrimidines; Risperidone; Time Factors | 2008 |
Paliperidone: An improvement over risperidone?
Topics: Administration, Oral; Antipsychotic Agents; Delayed-Action Preparations; Humans; Isoxazoles; Marketing; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia | 2008 |
Validated LC-MS/MS methods for the determination of risperidone and the enantiomers of 9-hydroxyrisperidone in human plasma and urine.
Topics: Chromatography, Liquid; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Risperidone; Sensitivity and Specificity; Tandem Mass Spectrometry | 2008 |
Long-term therapeutic drug monitoring of risperidone and olanzapine identifies altered steady-state pharmacokinetics: a clinical, two-group, naturalistic study.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antipsychotic Agents; Benzodiazepines; Biotransformation; Cytochrome P-450 CYP2D6; Drug Monitoring; Female; Humans; Inpatients; Isoxazoles; Male; Mental Disorders; Middle Aged; Olanzapine; Paliperidone Palmitate; Pyrimidines; Regression Analysis; Risperidone; Schizophrenia; Young Adult | 2008 |
ABCB1 polymorphisms influence steady-state plasma levels of 9-hydroxyrisperidone and risperidone active moiety.
Topics: Adult; Alleles; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Female; Genetic Variation; Genotype; Haplotypes; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Polymorphism, Genetic; Pyrimidines; Risperidone | 2008 |
Impact of multiple inhibitors or substrates of cytochrome P450 2D6 on plasma risperidone levels in patients on polypharmacy.
Topics: Adult; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Polypharmacy; Pyrimidines; Risperidone; Substrate Specificity | 2008 |
Effects of quetiapine, risperidone, 9-hydroxyrisperidone and ziprasidone on the survival of human neuronal and immune cells in vitro.
Topics: Adenosine Triphosphate; Antipsychotic Agents; Cell Line; Cell Survival; Dibenzothiazepines; Dose-Response Relationship, Drug; Energy Metabolism; Humans; Isoxazoles; Monocytes; Neurons; Paliperidone Palmitate; Piperazines; Pyrimidines; Quetiapine Fumarate; Risperidone; Thiazoles | 2010 |
[Paliperidone--a novel second-generation antipsychotic].
Topics: Antipsychotic Agents; Delayed-Action Preparations; Evidence-Based Medicine; Half-Life; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Risperidone; Treatment Outcome | 2008 |
Population pharmacokinetic analysis for risperidone using highly sparse sampling measurements from the CATIE study.
Topics: Adult; Age Factors; Aged; Alzheimer Disease; Antipsychotic Agents; Biological Availability; Body Weight; Female; Humans; Isoxazoles; Male; Metabolic Clearance Rate; Middle Aged; Models, Chemical; Models, Statistical; Paliperidone Palmitate; Pyrimidines; Randomized Controlled Trials as Topic; Risperidone; Sample Size; Sampling Studies; Schizophrenia | 2008 |
Pharmacological analysis of the novel, rapid, and potent inactivation of the human 5-Hydroxytryptamine7 receptor by risperidone, 9-OH-Risperidone, and other inactivating antagonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cell Line; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Receptors, Serotonin; Risperidone; Serotonin Antagonists | 2009 |
Study of the complexation of risperidone and 9-hydroxyrisperidone with cyclodextrin hosts using affinity capillary electrophoresis and (1)H NMR spectroscopy.
Topics: Antipsychotic Agents; Cyclodextrins; Electrophoresis, Capillary; Isoxazoles; Magnetic Resonance Spectroscopy; Molecular Structure; Paliperidone Palmitate; Pyrimidines; Risperidone; Thermodynamics | 2008 |
An agonist-antagonist interaction model for prolactin release following risperidone and paliperidone treatment.
Topics: Drug Interactions; Female; Humans; Isoxazoles; Male; Models, Biological; Paliperidone Palmitate; Prolactin; Pyrimidines; Risperidone | 2009 |
Sensitivity of older patients to antipsychotic motor side effects: a PET study examining potential mechanisms.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Basal Ganglia Diseases; Case-Control Studies; Cross-Sectional Studies; Dopamine Antagonists; Female; Humans; Isoxazoles; Male; Middle Aged; Ontario; Paliperidone Palmitate; Positron-Emission Tomography; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrimidines; Raclopride; Receptors, Dopamine D2; Risperidone; Schizophrenia; Treatment Outcome | 2009 |
Determination of risperidone and 9-Hydroxyrisperidone using HPLC, in plasma of children and adolescents with emotional and behavioural disorders.
Topics: Adolescent; Antipsychotic Agents; Child; Chromatography, High Pressure Liquid; Female; Humans; Isoxazoles; Linear Models; Male; Mental Disorders; Paliperidone Palmitate; Pyrimidines; Reproducibility of Results; Risperidone; Sensitivity and Specificity | 2009 |
Effects of the CYP2D6*10 alleles and co-medication with CYP2D6-dependent drugs on risperidone metabolism in patients with schizophrenia.
Topics: Adult; Alleles; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Drug Therapy, Combination; Female; Genotype; Humans; Isoxazoles; Male; Oligonucleotide Array Sequence Analysis; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Regression Analysis; Risperidone; Schizophrenia | 2009 |
Relationship between response to risperidone, plasma concentrations of risperidone and CYP3A4 polymorphisms in schizophrenia patients.
Topics: Adolescent; Adult; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; DNA; Dose-Response Relationship, Drug; Female; Genotype; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Polymorphism, Genetic; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Young Adult | 2010 |
Effects of CYP2D6 and CYP3A5 genotypes on the plasma concentrations of risperidone and 9-hydroxyrisperidone in Korean schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Asian People; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Female; Genotype; Humans; Isoxazoles; Korea; Male; Middle Aged; Paliperidone Palmitate; Polymorphism, Genetic; Pyrimidines; Risperidone; Schizophrenia | 2009 |
Pharmacokinetics and efficacy of a direct switch from conventional depot to risperidone long-acting injection in Chinese patients with schizophrenic and schizoaffective disorders.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antipsychotic Agents; Asian People; Delayed-Action Preparations; Dyskinesia, Drug-Induced; Female; Humans; Injections, Intramuscular; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrimidines; Risperidone; Schizophrenia; Treatment Outcome; White People | 2009 |
Clinical response to risperidone in relation to plasma drug concentrations in acutely exacerbated schizophrenic patients.
Topics: Adult; Aged; Antipsychotic Agents; Anxiety; Cognition; Data Interpretation, Statistical; Depression; Female; Hospitalization; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Young Adult | 2010 |
Human 5-HT7 receptor-induced inactivation of forskolin-stimulated adenylate cyclase by risperidone, 9-OH-risperidone and other "inactivating antagonists".
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Cell Line; Colforsin; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Receptors, Serotonin; Risperidone; Serotonin Antagonists | 2009 |
Serum levels of risperidone and its metabolite, 9-hydroxyrisperidone: correlation between drug concentration and clinical response.
Topics: Adult; Antipsychotic Agents; Attention; Blood Chemical Analysis; Discrimination Learning; Drug Monitoring; Female; Humans; Hydroxylation; Isoxazoles; Liver; Male; Neuropsychological Tests; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenic Psychology | 2009 |
Simultaneous determination of risperidone and 9-hydroxyrisperidone enantiomers in human blood plasma by liquid chromatography with electrochemical detection.
Topics: Antipsychotic Agents; Buffers; Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Liquid; Electrochemistry; Humans; Isoxazoles; Methanol; Paliperidone Palmitate; Phosphates; Pyrimidines; Reproducibility of Results; Risperidone; Stereoisomerism; Time Factors | 2009 |
Time resolved analysis of risperidone and 9-hydroxy-risperidone in hair using LC/MS-MS.
Topics: Adult; Antipsychotic Agents; Chromatography, Liquid; Hair; Humans; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Tandem Mass Spectrometry; Time Factors | 2009 |
A comparison of continuous subcutaneous paliperidone infusion and repeated subcutaneous injection of risperidone free-base in rats.
Topics: Animals; Antipsychotic Agents; Dextroamphetamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Administration Schedule; Infusions, Subcutaneous; Injections, Subcutaneous; Isoxazoles; Locomotion; Male; Paliperidone Palmitate; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone | 2010 |
Effects of the antipsychotic risperidone on dopamine synthesis in human brain measured by positron emission tomography with L-[beta-11C]DOPA: a stabilizing effect for dopaminergic neurotransmission?
Topics: Adult; Antipsychotic Agents; Brain; Carbon Radioisotopes; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Humans; Isoxazoles; Levodopa; Male; Paliperidone Palmitate; Positron-Emission Tomography; Putamen; Pyrimidines; Raclopride; Receptors, Dopamine D2; Rest; Risperidone; Synaptic Transmission; Young Adult | 2009 |
Impact of CYP2D6 genotype on steady-state serum concentrations of risperidone and 9-hydroxyrisperidone in patients using long-acting injectable risperidone.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Cytochrome P-450 CYP2D6; Delayed-Action Preparations; Female; Genotype; Humans; Injections, Intramuscular; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Retrospective Studies; Risperidone; Time Factors; Young Adult | 2009 |
Inconsistency in risperidone long-acting injection steady-state plasma levels when switching from deltoid to gluteal administration.
Topics: Adult; Antipsychotic Agents; Buttocks; Delayed-Action Preparations; Humans; Injections, Intramuscular; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Shoulder | 2010 |
Remission of drug-induced hepatitis after switching from risperidone to paliperidone.
Topics: Adult; Antipsychotic Agents; Biotransformation; Chemical and Drug Induced Liver Injury; Clozapine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Isoxazoles; Liver Function Tests; Paliperidone Palmitate; Pyrimidines; Reference Values; Risperidone; Schizophrenia | 2010 |
Serum concentrations, therapeutic response and side effects in children and adolescents with impulsive-aggressive symptoms during risperidone therapy.
Topics: Adolescent; Age Factors; Aggression; Antipsychotic Agents; Child; Child Behavior Disorders; Disruptive, Impulse Control, and Conduct Disorders; Dose-Response Relationship, Drug; Female; Humans; Isoxazoles; Linear Models; Male; Paliperidone Palmitate; Prospective Studies; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Sex Factors; Treatment Outcome | 2010 |
Serum concentrations of paliperidone versus risperidone and clinical effects.
Topics: Adult; Antipsychotic Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Monitoring; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Retrospective Studies; Risperidone | 2010 |
The role of CYP2D6 and ABCB1 pharmacogenetics in drug-naïve patients with first-episode schizophrenia treated with risperidone.
Topics: Adult; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Female; Genotype; Humans; Isoxazoles; Male; Middle Aged; Mutation; Paliperidone Palmitate; Pyrimidines; Risperidone; Sample Size; Schizophrenia; Treatment Outcome | 2010 |
Studies on the acute toxicity, pharmacokinetics and pharmacodynamics of paliperidone derivatives--comparison to paliperidone and risperidone in mice and rats.
Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Electrocardiography; Excitatory Amino Acid Antagonists; Female; Heart; Heart Rate; Hyperkinesis; Isoxazoles; Lethal Dose 50; Male; Maximum Tolerated Dose; Mice; Mice, Inbred Strains; Paliperidone Palmitate; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone; Schizophrenia; Toxicity Tests, Acute | 2010 |
Differential effects of antipsychotic and antidepressant drugs on neurogenic regions in rats.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Cell Count; Cell Proliferation; Dose-Response Relationship, Drug; Fluoxetine; Hippocampus; Isoxazoles; Lateral Ventricles; Male; Neurogenesis; Neurons; Olfactory Mucosa; Paliperidone Palmitate; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone; Selective Serotonin Reuptake Inhibitors | 2010 |
Clozapine and other competitive antagonists reactivate risperidone-inactivated h5-HT7 receptors: radioligand binding and functional evidence for GPCR homodimer protomer interactions.
Topics: Binding, Competitive; Biosensing Techniques; Cell Line; Clozapine; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Isoxazoles; Paliperidone Palmitate; Protein Binding; Protein Multimerization; Protein Subunits; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Transfection | 2010 |
Are the long-acting intramuscular formulations of risperidone or paliperidone palmitate associated with post-injection delirium/sedation syndrome? An assessment of safety databases.
Topics: Chemistry, Pharmaceutical; Clinical Trials as Topic; Conscious Sedation; Databases, Factual; Delayed-Action Preparations; Delirium; Humans; Injections, Intramuscular; Isoxazoles; Paliperidone Palmitate; Palmitates; Prospective Studies; Risperidone; Syndrome | 2011 |
Effect of cyamemazine on the steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: a preliminary retrospective study.
Topics: Adolescent; Adult; Antipsychotic Agents; Chromatography, High Pressure Liquid; Drug Interactions; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Phenothiazines; Pyrimidines; Retrospective Studies; Risperidone; Spectrophotometry, Ultraviolet | 2010 |
Analysis of risperidone and 9-hydroxyrisperidone in human plasma, urine and saliva by MEPS-LC-UV.
Topics: Chromatography, Liquid; Humans; Isoxazoles; Linear Models; Paliperidone Palmitate; Psychotic Disorders; Pyrimidines; Reproducibility of Results; Risperidone; Saliva; Sensitivity and Specificity; Solid Phase Microextraction; Spectrophotometry, Ultraviolet | 2011 |
Paliperidone ER and oral risperidone in patients with schizophrenia: a comparative database analysis.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Databases as Topic; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Propensity Score; Psychiatric Status Rating Scales; Pyrimidines; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Treatment Outcome | 2011 |
The interaction of antipsychotic drugs with lipids and subsequent lipid reorganization investigated using biophysical methods.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antipsychotic Agents; Calorimetry, Differential Scanning; Cell Membrane; Cholesterol; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Isoxazoles; Membrane Lipids; Membranes, Artificial; Microscopy, Fluorescence; Models, Molecular; Molecular Conformation; Molecular Structure; Paliperidone Palmitate; Phosphatidylcholines; Pyrimidines; Receptors, Dopamine D2; Risperidone; Sphingomyelins; Structure-Activity Relationship; Surface Plasmon Resonance; X-Ray Diffraction | 2011 |
Effects of risperidone and paliperidone pre-treatment on locomotor response following prenatal immune activation.
Topics: Amphetamine; Animals; Animals, Newborn; Antipsychotic Agents; Central Nervous System Stimulants; Disease Models, Animal; Drug Interactions; Female; Isoxazoles; Motor Activity; Paliperidone Palmitate; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone; Schizophrenia; Time Factors | 2011 |
Differential effects of antipsychotic medications on polyunsaturated fatty acid biosynthesis in rats: Relationship with liver delta6-desaturase expression.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Drinking Water; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Haloperidol; Isoxazoles; Linoleoyl-CoA Desaturase; Liver; Male; Olanzapine; Paliperidone Palmitate; Pyrimidines; Quetiapine Fumarate; Rats; Rats, Long-Evans; Risperidone; RNA, Messenger | 2011 |
Predictors of risperidone and 9-hydroxyrisperidone serum concentration in children and adolescents.
Topics: Adolescent; Aging; Antipsychotic Agents; Body Mass Index; Child; Child Development Disorders, Pervasive; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Mental Disorders; Paliperidone Palmitate; Polypharmacy; Psychotic Disorders; Pyrimidines; Risperidone; Sex Factors; Sexual Development | 2011 |
Risk of arrest in persons with schizophrenia and bipolar disorder in a Florida Medicaid program: the role of atypical antipsychotics, conventional neuroleptics, and routine outpatient behavioral health services.
Topics: Adolescent; Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Clozapine; Crime; Delayed-Action Preparations; Dibenzothiazepines; Female; Florida; Humans; Isoxazoles; Male; Medicaid; Middle Aged; Olanzapine; Outpatients; Paliperidone Palmitate; Piperazines; Propensity Score; Pyrimidines; Quetiapine Fumarate; Quinolones; Risk Factors; Risperidone; Schizophrenia; Treatment Outcome; United States; Young Adult | 2011 |
MultiSimplex optimization of chromatographic separation and dansyl derivatization conditions in the ultra performance liquid chromatography-tandem mass spectrometry analysis of risperidone, 9-hydroxyrisperidone, monoamine and amino acid neurotransmitters
Topics: Biogenic Monoamines; Case-Control Studies; Chromatography, High Pressure Liquid; Dansyl Compounds; Humans; Isoxazoles; Multivariate Analysis; Neurotransmitter Agents; Paliperidone Palmitate; Pyrimidines; Reproducibility of Results; Risperidone; Schizophrenia; Sensitivity and Specificity; Tandem Mass Spectrometry | 2011 |
Effect of paliperidone and risperidone on extracellular glutamate in the prefrontal cortex of rats exposed to prenatal immune activation or MK-801.
Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Extracellular Space; Female; Glutamic Acid; Isoxazoles; Male; Maternal Exposure; Paliperidone Palmitate; Poly I-C; Prefrontal Cortex; Pregnancy; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Risperidone; Schizophrenia | 2011 |
Comparing the influence of dopamine D₂ polymorphisms and plasma drug concentrations on the clinical response to risperidone.
Topics: Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Drug Monitoring; Female; Genotype; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Polymorphism, Genetic; Pyrimidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Young Adult | 2011 |
Neurotoxic/neuroprotective activity of haloperidol, risperidone and paliperidone in neuroblastoma cells.
Topics: Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Humans; Isoxazoles; Neuroblastoma; Neuroprotective Agents; Paliperidone Palmitate; Pyrimidines; Risperidone | 2012 |
Enantioselective fungal biotransformation of risperidone in liquid culture medium by capillary electrophoresis and hollow fiber liquid-phase microextraction.
Topics: Analysis of Variance; Biotransformation; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Isoxazoles; Linear Models; Liquid Phase Microextraction; Mucor; Paliperidone Palmitate; Pilot Projects; Pyrimidines; Reproducibility of Results; Risperidone; Sensitivity and Specificity; Stereoisomerism | 2011 |
Manic symptoms during a switch from risperidone to paliperidone: a case report.
Topics: Antipsychotic Agents; Bipolar Disorder; Female; Follow-Up Studies; Humans; Isoxazoles; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia | 2011 |
Anaphylactoid reaction to paliperidone palmitate extended-release injectable suspension in a patient tolerant of oral risperidone.
Topics: Administration, Oral; Adult; Anaphylaxis; Antipsychotic Agents; Delayed-Action Preparations; Humans; Injections, Intramuscular; Isoxazoles; Male; Paliperidone Palmitate; Palmitates; Risperidone; Schizophrenia; Suspensions | 2012 |
[Case of schizophrenia in which depressive and negative symptoms relapsed on switching from oral risperidone to risperidone long-acting injection].
Topics: Administration, Ophthalmic; Antipsychotic Agents; Delayed-Action Preparations; Drug Substitution; Humans; Injections; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Receptors, Adrenergic, alpha-2; Recurrence; Risperidone; Schizophrenia; Schizophrenic Psychology | 2011 |
Relationship between dose, drug levels, and D2 receptor occupancy for the atypical antipsychotics risperidone and paliperidone.
Topics: Animals; Antipsychotic Agents; Brain; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Isoxazoles; Macaca mulatta; Male; Paliperidone Palmitate; Positron-Emission Tomography; Protein Binding; Pyrimidines; Receptors, Dopamine D2; Risperidone | 2012 |
Emergence of neuroleptic malignant syndrome while switching between risperidone and paliperidone.
Topics: Adult; Antipsychotic Agents; Humans; Isoxazoles; Male; Neuroleptic Malignant Syndrome; Paliperidone Palmitate; Psychotic Disorders; Pyrimidines; Risperidone | 2011 |
A change from risperidone long acting injection to paliperidone palmitate in an elderly patient--a cautionary tale.
Topics: Aged; Antipsychotic Agents; Female; Humans; Isoxazoles; Paliperidone Palmitate; Palmitates; Recurrence; Risperidone; Schizophrenia; Treatment Failure | 2012 |
Pharmacokinetic-pharmacodynamic modeling of the D₂ and 5-HT (2A) receptor occupancy of risperidone and paliperidone in rats.
Topics: Animals; Antipsychotic Agents; Brain; Isoxazoles; Male; Models, Biological; Paliperidone Palmitate; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Risperidone | 2012 |
Publication bias in antipsychotic trials: an analysis of efficacy comparing the published literature to the US Food and Drug Administration database.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Databases, Factual; Dibenzothiazepines; Humans; Isoxazoles; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Publication Bias; Pyrimidines; Quetiapine Fumarate; Quinolones; Risperidone; United States; United States Food and Drug Administration | 2012 |
Cost effectiveness of paliperidone palmitate versus risperidone long-acting injectable and olanzapine pamoate for the treatment of patients with schizophrenia in Sweden.
Topics: Antipsychotic Agents; Benzodiazepines; Cost-Benefit Analysis; Drug Substitution; Female; Health Resources; Humans; Injections; Isoxazoles; Male; Markov Chains; Models, Economic; Olanzapine; Paliperidone Palmitate; Palmitates; Quality-Adjusted Life Years; Recurrence; Risperidone; Schizophrenia; Sweden | 2012 |
Risperidone and total 9-hydroxyrisperidone in relation to prescribed dose and other factors: data from a therapeutic drug monitoring service, 2002-2010.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Databases, Factual; Drug Monitoring; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone; Treatment Outcome; Young Adult | 2012 |
Blonanserin, a novel atypical antipsychotic agent not actively transported as substrate by P-glycoprotein.
Topics: Animals; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Brain; Cell Line, Transformed; Humans; Isoxazoles; LLC-PK1 Cells; Mice; Mice, Inbred Strains; Mice, Knockout; Paliperidone Palmitate; Piperazines; Piperidines; Pyrimidines; Risperidone; Swine | 2012 |
Effect of the cytochrome P450 2D6*10 allele on risperidone metabolism in Japanese psychiatric patients.
Topics: Adult; Alleles; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Female; Humans; Isoxazoles; Japan; Male; Middle Aged; Paliperidone Palmitate; Psychotic Disorders; Pyrimidines; Risperidone; Schizophrenia; Young Adult | 2012 |
Solid phase microextraction and LC-MS/MS for the determination of paliperidone after stereoselective fungal biotransformation of risperidone.
Topics: Biotransformation; Chromatography, Liquid; Culture Media; Cunninghamella; Isoxazoles; Molecular Structure; Paliperidone Palmitate; Pyrimidines; Risperidone; Solid Phase Microextraction; Solvents; Stereoisomerism; Tandem Mass Spectrometry | 2012 |
An evaluation of using rat-derived single-dose neuropharmacokinetic parameters to project accurately large animal unbound brain drug concentrations.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Brain Chemistry; Dogs; Isoxazoles; Male; Paliperidone Palmitate; Primates; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone; Thiophenes | 2012 |
Population pharmacokinetic modeling of risperidone and 9-hydroxyrisperidone to estimate CYP2D6 subpopulations in children and adolescents.
Topics: Adolescent; Antipsychotic Agents; Child; Child, Preschool; Cohort Studies; Cytochrome P-450 CYP2D6; Female; Genotype; Humans; Isoxazoles; Male; Mental Disorders; Paliperidone Palmitate; Phenotype; Prospective Studies; Pyrimidines; Risperidone | 2012 |
A cross-sectional study of plasma risperidone levels with risperidone long-acting injectable: implications for dopamine D2 receptor occupancy during maintenance treatment in schizophrenia.
Topics: Adult; Aged; Antipsychotic Agents; Cross-Sectional Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gas Chromatography-Mass Spectrometry; Humans; Injections, Intramuscular; Isoxazoles; Long-Term Care; Male; Middle Aged; Paliperidone Palmitate; Positron-Emission Tomography; Psychiatric Status Rating Scales; Pyrimidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Schizophrenic Psychology; Young Adult | 2012 |
Risperidone/paliperidone induced neutropenia and lymphopenia.
Topics: Antipsychotic Agents; Humans; Isoxazoles; Lymphopenia; Male; Middle Aged; Neutropenia; Paliperidone Palmitate; Pyrimidines; Risperidone | 2013 |
Bacterial degradation of risperidone and paliperidone in decomposing blood.
Topics: Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Drug Stability; Forensic Toxicology; Gram-Positive Bacteria; Isoxazoles; Paliperidone Palmitate; Postmortem Changes; Pyrimidines; Risperidone; Specimen Handling; Spectrometry, Mass, Electrospray Ionization; Swine; Temperature | 2013 |
Paliperidone as an alternative for risperidone in a case of schizophrenia with retrograde ejaculation.
Topics: Adult; Antipsychotic Agents; Ejaculation; Humans; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia; Sexual Dysfunction, Physiological | 2012 |
Effects of single or repeated silymarin administration on pharmacokinetics of risperidone and its major metabolite, 9-hydroxyrisperidone in rats.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Injections, Intravenous; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone; Silymarin | 2013 |
Changes in prolactin levels and sexual function in young psychotic patients after switching from long-acting injectable risperidone to paliperidone palmitate.
Topics: Adult; Age Factors; Antipsychotic Agents; Biomarkers; Drug Substitution; Female; Humans; Hyperprolactinemia; Injections; Isoxazoles; Male; Paliperidone Palmitate; Palmitates; Prolactin; Prospective Studies; Psychiatric Status Rating Scales; Psychotic Disorders; Recovery of Function; Risperidone; Sexual Behavior; Sexual Dysfunction, Physiological; Surveys and Questionnaires; Time Factors; Treatment Outcome; Young Adult | 2013 |
Risk of hyperprolactinemia and sexual side effects in males 10-20 years old diagnosed with autism spectrum disorders or disruptive behavior disorder and treated with risperidone.
Topics: Adolescent; Adult; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Child Development Disorders, Pervasive; Cross-Sectional Studies; Dose-Response Relationship, Drug; Gynecomastia; Humans; Hyperprolactinemia; Isoxazoles; Logistic Models; Male; Paliperidone Palmitate; Prolactin; Pyrimidines; Risperidone; Sexual Dysfunction, Physiological; Statistics, Nonparametric; Surveys and Questionnaires; Time Factors; Young Adult | 2012 |
Treating residual insomnia in schizophrenia: examining the options.
Topics: Antipsychotic Agents; Central Nervous System Depressants; Humans; Isoxazoles; Melatonin; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia; Sleep Initiation and Maintenance Disorders | 2013 |
LC-MS/MS of some atypical antipsychotics in human plasma, serum, oral fluid and haemolysed whole blood.
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chromatography, Liquid; Clozapine; Dibenzothiazepines; Female; Forensic Toxicology; Hemolysis; Humans; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperazines; Pyrimidines; Quetiapine Fumarate; Quinolones; Reproducibility of Results; Risperidone; Saliva; Serum; Sulpiride; Tandem Mass Spectrometry | 2013 |
Adherence challenges and long-acting injectable antipsychotic treatment in patients with schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Delayed-Action Preparations; Fluphenazine; Haloperidol; Humans; Injections; Isoxazoles; Medication Adherence; Olanzapine; Paliperidone Palmitate; Palmitates; Risperidone; Schizophrenia | 2013 |
Stability of some atypical antipsychotics in human plasma, haemolysed whole blood, oral fluid, human serum and calf serum.
Topics: Amisulpride; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cattle; Chromatography, Liquid; Clozapine; Dibenzothiazepines; Drug Stability; Female; Forensic Toxicology; Hemolysis; Humans; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperazines; Pyrimidines; Quetiapine Fumarate; Quinolones; Reproducibility of Results; Risperidone; Saliva; Serum; Sulpiride; Tandem Mass Spectrometry | 2013 |
Impact of the ABCB1 gene polymorphism on plasma 9-hydroxyrisperidone and active moiety levels in Japanese patients with schizophrenia.
Topics: Adult; Age Factors; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP2D6; Female; Genotype; Humans; Isoxazoles; Japan; Male; Middle Aged; Paliperidone Palmitate; Polymorphism, Genetic; Pyrimidines; Regression Analysis; Risperidone; Schizophrenia; Young Adult | 2013 |
Economic and clinical comparison of atypical depot antipsychotic drugs for treatment of chronic schizophrenia in the Czech Republic.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Cost-Benefit Analysis; Czech Republic; Decision Support Techniques; Delayed-Action Preparations; Drug Costs; Economics, Pharmaceutical; Female; Humans; Isoxazoles; Male; Multivariate Analysis; Olanzapine; Paliperidone Palmitate; Palmitates; Quality-Adjusted Life Years; Risperidone; Schizophrenia; Young Adult | 2013 |
Signalling profile differences: paliperidone versus risperidone.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Arrestins; beta-Arrestins; CHO Cells; Cricetinae; Cricetulus; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Inverse Agonism; Extracellular Signal-Regulated MAP Kinases; Histamine Agonists; Humans; Isoxazoles; Molecular Structure; Paliperidone Palmitate; Pyrimidines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D2; Receptors, Histamine H1; Risperidone; Serotonin Receptor Agonists; Signal Transduction; Structure-Activity Relationship; Transfection | 2013 |
Cost-effectiveness analysis of atypical long-acting antipsychotics for treating chronic schizophrenia in Finland.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Cost-Benefit Analysis; Decision Support Techniques; Delayed-Action Preparations; Drug Costs; Economics, Pharmaceutical; Female; Finland; Humans; Isoxazoles; Male; Multivariate Analysis; Olanzapine; Paliperidone Palmitate; Palmitates; Quality-Adjusted Life Years; Risperidone; Schizophrenia; Young Adult | 2013 |
The effect of the Taq1A variant in the dopamine D₂ receptor gene and common CYP2D6 alleles on prolactin levels in risperidone-treated boys.
Topics: Adolescent; Alleles; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Child Development Disorders, Pervasive; Cytochrome P-450 CYP2D6; Drug Administration Schedule; Genetic Variation; Humans; Hyperprolactinemia; Isoxazoles; Male; Paliperidone Palmitate; Polymorphism, Genetic; Prolactin; Pyrimidines; Receptors, Dopamine D2; Risperidone; Young Adult | 2013 |
Microsphere delivery of Risperidone as an alternative to combination therapy.
Topics: Animals; Antipsychotic Agents; Area Under Curve; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Delivery Systems; Isoxazoles; Lactic Acid; Male; Microspheres; Paliperidone Palmitate; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone; Time Factors | 2013 |
Johnson & Johnson to pay $2.2bn to settle charges of false marketing on three drugs.
Topics: Consumer Product Safety; Drug Industry; Fraud; Humans; Isoxazoles; Marketing; Natriuretic Peptide, Brain; Paliperidone Palmitate; Pyrimidines; Risperidone; United States; United States Food and Drug Administration | 2013 |
Pharmacoeconomics of depot antipsychotics for treating chronic schizophrenia in Sweden.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Cost of Illness; Cost-Benefit Analysis; Delayed-Action Preparations; Drug Costs; Female; Haloperidol; Health Care Costs; Hospitalization; Humans; Isoxazoles; Male; Middle Aged; Models, Econometric; Olanzapine; Paliperidone Palmitate; Palmitates; Quality-Adjusted Life Years; Risperidone; Schizophrenia; Sweden | 2014 |
Atypical antipsychotics such as risperidone, but not paliperidone, worsen vascular endothelial function via upregulation of adhesion molecules VCAM-1, ICAM-1, and E-selectin in diabetic rats.
Topics: Animals; Antipsychotic Agents; Aorta; Blood Pressure; Cell Adhesion Molecules; Chemokine CCL2; Cytokines; Diabetes Mellitus, Experimental; Diet, High-Fat; E-Selectin; Endothelium, Vascular; Glucose; Insulin Resistance; Isoxazoles; Lipids; Male; Paliperidone Palmitate; Pyrimidines; Rats; Rats, Wistar; Risperidone; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2013 |
Lower risk for body weight gain and better control of appetite after switching risperidone to paliperidone in a schizoaffective patient.
Topics: Adult; Antipsychotic Agents; Appetite; Body Weight; Female; Humans; Isoxazoles; Paliperidone Palmitate; Psychotic Disorders; Pyrimidines; Risperidone | 2014 |
Dopamine D2 receptor occupancy as a predictor of catalepsy in rats: a pharmacokinetic-pharmacodynamic modeling approach.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Catalepsy; Computer Simulation; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Humans; Isoxazoles; Markov Chains; Models, Biological; Olanzapine; Paliperidone Palmitate; Pyrimidines; Rats; Receptors, Dopamine D2; Risperidone; Severity of Illness Index | 2014 |
Relationship between the plasma concentration of paliperidone and the clinical and drug-induced extrapyramidal symptoms in elderly patients with schizophrenia.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Blood Chemical Analysis; Chromatography, Liquid; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Prospective Studies; Pyrimidines; Risperidone; Schizophrenia; Severity of Illness Index; Tandem Mass Spectrometry; Treatment Outcome | 2014 |
Expanding Therapy With Long-Acting Antipsychotic Medication in Patients With Schizophrenia.
Topics: Early Medical Intervention; Female; Humans; Isoxazoles; Male; Palmitates; Risperidone; Schizophrenia; Secondary Prevention | 2015 |
ADN-1184, a monoaminergic ligand with 5-HT6/7 receptor antagonist action, exhibits activity in animal models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Aripiprazole; Behavior, Animal; Benzodiazepines; Conditioning, Psychological; Conflict, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Isoxazoles; Male; Maze Learning; Mice; Motor Activity; Olanzapine; Punishment; Rats, Wistar; Reaction Time; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Sulfonamides | 2016 |
[Therapeutic drug monitoring of risperidone and its active metabolite 9-hydroxyrisperidone in the treatment of schizophrenia].
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Risperidone; Schizophrenia | 2019 |
Effect of CYP2D6 polymorphisms on plasma concentration and therapeutic effect of risperidone.
Topics: Antipsychotic Agents; Cytochrome P-450 CYP2D6; Humans; Isoxazoles; Paliperidone Palmitate; Plasma; Pyrimidines; Risperidone | 2021 |
A liquid chromatography-miniature mass spectrometry (LC-Mini MS) method for quantitative analysis of risperidone and 9-hydroxyrisperidone in plasma.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Reproducibility of Results; Risperidone; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2023 |