Compounds > isoxazoles
Page last updated: 2024-08-21

isoxazoles and nvp-bep800

isoxazoles has been researched along with nvp-bep800 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brough, PA; Brueggen, J; Chène, P; Drysdale, MJ; Garcia-Echeverria, C; Jensen, MR; Massey, AJ; Pfaar, U; Radimerski, T; Ruetz, S; Schoepfer, J; Schweitzer, A; Wood, M1
Chatterjee, M; Djuzenova, CS; Flentje, M; Jensen, MR; Stingl, L; Stühmer, T1
Biehl, M; Djuzenova, CS; Flentje, M; Günther, N; Hartmann, S; Katzer, A; Krohne, G; Kuger, S; Sukhorukov, VL; Worschech, E; Zimmermann, H1

Other Studies

3 other study(ies) available for isoxazoles and nvp-bep800

ArticleYear
Preclinical antitumor activity of the orally available heat shock protein 90 inhibitor NVP-BEP800.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:4

    Topics: Administration, Oral; Animals; Apoptosis; Biological Availability; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Mice; Mice, Nude; Protein Processing, Post-Translational; Pyrimidines; Resorcinols; Xenograft Model Antitumor Assays

2010
Novel HSP90 inhibitors, NVP-AUY922 and NVP-BEP800, radiosensitise tumour cells through cell-cycle impairment, increased DNA damage and repair protraction.
    British journal of cancer, 2010, May-25, Volume: 102, Issue:11

    Topics: Benzoquinones; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Down-Regulation; Drug Evaluation, Preclinical; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Lactams, Macrocyclic; Neoplasms; Pyrimidines; Radiation Tolerance; Radiation-Sensitizing Agents; Resorcinols; Up-Regulation

2010
Hsp90 inhibition by NVP-AUY922 and NVP-BEP800 decreases migration and invasion of irradiated normoxic and hypoxic tumor cell lines.
    Cancer letters, 2013, May-01, Volume: 331, Issue:2

    Topics: Blotting, Western; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Flow Cytometry; Glioblastoma; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Lung Neoplasms; Microscopy, Electron, Scanning; Neoplasm Invasiveness; Pyrimidines; Resorcinols; Wound Healing

2013