isoxazoles has been researched along with nms-e973 in 3 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ballinari, D; Brasca, MG; Casale, E; Ciomei, M; De Ponti, A; Degrassi, A; Donati, D; Felder, E; Fogliatto, G; Galvani, A; Germani, M; Gianellini, L; Guanci, M; Isacchi, A; Mantegani, S; Paolucci, M; Pesenti, E; Polucci, P; Russo, M; Sola, F; Valsasina, B; Visco, C; Zuccotto, F | 1 |
Amboldi, N; Bindi, S; Brasca, MG; Caronni, D; Casale, E; Ceccarelli, W; Colombo, N; De Ponti, A; Donati, D; Ermoli, A; Fachin, G; Felder, ER; Ferguson, RD; Fiorelli, C; Fogliatto, G; Guanci, M; Isacchi, A; Mantegani, S; Pesenti, E; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F | 1 |
Barbagallo, I; Li Volti, G; Onni, T; Parenti, R; Pepe, F; Tibullo, D; Vanella, L; ZappalĂ , A | 1 |
3 other study(ies) available for isoxazoles and nms-e973
Article | Year |
---|---|
NMS-E973, a novel synthetic inhibitor of Hsp90 with activity against multiple models of drug resistance to targeted agents, including intracranial metastases.
Topics: Animals; Antineoplastic Agents; Binding Sites; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; HSP90 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Isoxazoles; Mice; Molecular Conformation; Molecular Docking Simulation; Neoplasm Metastasis; Organ Specificity; Protein Binding; Proteolysis; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90).
Topics: Animals; Antineoplastic Agents; Binding Sites; Biomarkers, Tumor; Catalytic Domain; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Female; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Protein Binding; Structure-Activity Relationship; Transplantation, Heterologous | 2013 |
Combined inhibition of Hsp90 and heme oxygenase-1 induces apoptosis and endoplasmic reticulum stress in melanoma.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Heme Oxygenase-1; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Melanoma; Metalloporphyrins; Reactive Oxygen Species | 2015 |