isoxazoles has been researched along with morphine in 86 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (26.74) | 18.7374 |
| 1990's | 4 (4.65) | 18.2507 |
| 2000's | 26 (30.23) | 29.6817 |
| 2010's | 25 (29.07) | 24.3611 |
| 2020's | 8 (9.30) | 2.80 |
| Authors | Studies |
|---|---|
| Biggio, G; Brodie, BB; Costa, E; Guidotti, A | 1 |
| Arnt, J; Scheel-Krüger, J | 1 |
| Arnt, J; Christensen, AV; Scheel-Krüger, J | 1 |
| Bella, DD; Biggio, G; Frigeni, V; Guidotti, A | 1 |
| Bapna, JS; Rajaram, S; Ramaswamy, S | 1 |
| Bapna, JS; Ramaswamy, S; Srinivasan, B; Srinivasan, D | 1 |
| Bapna, JS; Ramaswamy, S; Suthakaran, C | 1 |
| Depaulis, A; Liebeskind, JC; Morgan, MM | 2 |
| Dafny, N; Enna, SJ; Reyes-Vazquez, C | 1 |
| Chapman, AG | 1 |
| Pelley, KA; Vaught, JL | 1 |
| Enna, SJ; Zorn, SH | 1 |
| Bloss, JL; Hammond, DL | 1 |
| Costa, LG; Murphy, SD | 1 |
| Dafny, N; Reyes-Vázquez, C | 1 |
| DeFeudis, FV | 1 |
| DeFeudis, FV; Grognet, A; Hertz, F | 3 |
| Andree, T; Enna, SJ; Kendall, DA | 1 |
| Cheney, DL; McGill, W; Murray, TF | 1 |
| Cagiano, R; Cuomo, V; Mocchetti, I; Racagni, G | 1 |
| Christensen, AV; Larsen, JJ | 1 |
| Buescher, HH; Hill, RC; Maurer, R; Roemer, D | 1 |
| Bapna, JS; Ramaswamy, S; Thirugnanasambantham, P; Viswanathan, S | 1 |
| Parvini, S; Pirali, M; Rezayat, M; Tabarrai, E; Zarrindast, MR | 1 |
| Hong, JT; Lee, MK; Oh, KW; Shin, IC; Yoon, IS | 1 |
| Hogue, C; Hubbard, RC; Rasmussen, GL; Steckner, K; Torri, S | 1 |
| Barton, SF; Dhadda, SS; Hubbard, RC; Kuss, ME; Langeland, FF; LeComte, D; Snabes, MC | 1 |
| Chen, X; Kariger, R; Li, S; Naruse, R; Norel, E; Quon, R; Sloninsky, A; Tang, J; Webb, T; Wender, RH; White, PF | 1 |
| Dhadda, S; Hubbard, RC; Naumann, TM; Traylor, L | 1 |
| Grossman, E; Hakki, SI; Hubbard, RC; Malan, TP; Marsh, G; Traylor, L | 1 |
| Davidson, AC; Ng, A; Smith, G | 1 |
| Alston, RP; Duke, PC; Feneck, RO; Hsu, PH; Hubbard, RC; Mangano, DT; Nussmeier, NA; Ott, E; Saidman, LJ; Snabes, MC | 1 |
| Katz, N | 1 |
| Chen, C; Cleeland, CS; Hanna, DB; Jensen, MP; Mendoza, T | 1 |
| Bajwa, ZH; Bikhazi, GB; Davis, DJ; Hubbard, RC; LeComte, D; Snabes, MC; Traylor, L | 1 |
| Gordon, S; Hubbard, R; Malan, TP; Snabes, M | 1 |
| Baechle, JP; Beaussier, M; Buffin, A; Didelot, JP; Goater, P; Lavazais, S; Lienhart, A; Loriferne, JF; Mosbah, A; Paugam, C; Perier, JF; Said, R; Weickmans, H | 1 |
| Chaterjee, A; Khalil, MW; Macbryde, G; Marks, RR; Sarkar, PK | 1 |
| Jia, H; Qu, CL; Tang, JS | 1 |
| Boye, ME; Brown, MT; Joshi, GP; Langford, RM; Nussmeier, NA; Singla, NK; Verburg, KM; Whelton, AA | 1 |
| Abdalla, H; Buckley, E; Butler, M; Iohom, G; Larney, V; O'Brien, J; Shorten, GD; Szarvas, S | 1 |
| Beaussier, M; Lienhart, A; Sean, PT; Tilleul, P; Weickmans, H | 1 |
| Bjerrum, OJ; Blackburn-Munro, G; Broløs, T; Jensen, DG; Rode, F; Thomsen, M | 1 |
| Bunburaphong, P; Niruthisard, S; Toleb, K; Ussawanophakiat, M; Werawataganon, T; Wongsakornchaikul, C | 1 |
| Bello, A; Dreyer, S; Eikermann, M; Klassen, PD; Peters, J; Riest, G; Stegen, B; Weiss, M | 1 |
| Foocharoen, T; Jirarattanaphochai, K; Jung, S; Lertsinudom, S; Pulnitiporn, A; Sriraj, W; Thienthong, S | 1 |
| Cormack, J; Jones, SJ; Murphy, MA; Scott, DA | 1 |
| Chambers, P; Johnson, CB; Kongara, K | 1 |
| Chambers, JP; Johnson, CB; Kongara, K | 1 |
| Tanavalee, A; Thiengwittayaporn, S | 1 |
| Dervenis, C; Kapota, E; Kostopanagiotou, G; Matsota, P; Pandazi, A; Paraskevopoulou, P | 1 |
| Cheu, NW; Chuang, FH; Liao, CH; Tan, TD; Wang, YR; Watts, MP; Wong, JO | 1 |
| Gu, MN; Hou, XM; Liu, GW; Liu, XJ; Xiao, JF | 1 |
| Leslie, K; Pemberton, E; Williams, DL | 1 |
| Gong, N; Hashimoto, K; Ma, AN; Wang, HL; Wang, YC; Wang, YX | 1 |
| Chen, XL; Guo, C; Huang, JL; Wang, YX | 1 |
| Bao, Y; Fang, J; Li, W; Liu, K; Luo, H; Peng, L; Yi, Y | 1 |
| Díaz-Ponce, H; Galindo-Suárez, RM; Muciño-Ortega, E; Walter-Tordecillas, MA | 1 |
| Wang, S; Wu, H; Wu, Y; Zhu, Y | 1 |
| Li, H; Nong, L; Sun, Y; Tian, Y | 1 |
| Arslan, R; Bektas, N; Ozturk, Y | 1 |
| Ba, YF; He, SH; Li, CS; Li, XD; Li, Y; Liu, YN; Ning, ZH; Wang, QH; Zhang, H; Zhang, X; Zhu, Y | 1 |
| Chang, PY; Chen, YC; Cheng, KI; Hsu, HT; Huang, HF; Lu, IC; Tseng, KY | 1 |
| Dirkmann, D; Eikermann, M; Farhan, H; Groeben, H; Stahl, DL | 1 |
| Li, J; Li, N; Peng, N; Yang, X | 1 |
| Chen, CL; Cheng, KW; Huang, CJ; Jawan, B; Juang, SE; Lee, YE; Lim, KI; Liu, CK; Shih, TH; Wang, CH; Wu, SC; Yang, SC | 1 |
| Huang, WQ; Liu, KX; Liu, WF; Peng, SL; Shu, HH; Xiao, JF; Zhang, GR; Zhao, GD | 1 |
| Borgeat, A; Boye, ME; Camu, F; Cheung, RY; Heylen, RJ; Viel, EJ | 1 |
| Li, CJ; Li, XY; Li, YW; Liu, C; Meng, ZT; Mu, DL; Wang, DX; Wang, G; Zhang, DZ | 1 |
| Pei, F; Shen, B; Si, H; Weng, X; Wu, Y; Yang, T; Zeng, Y | 1 |
| Bian, YY; Jin, J; Lin, J; Peng, HM; Qian, WW; Wang, LC; Weng, XS | 1 |
| Chang, CC; Chen, CY; Liao, YM; Lin, PC; Lin, YC | 1 |
| Bian, Y; Peng, H; Weng, X; Wu, Z; Xiao, K; Xiao, W; Yu, L | 1 |
| Ben Fadhel, K; Bousselmi, J; Haddad, F; Jaoua, H; Mrabet, A | 1 |
| Borgeat, A; Camu, F; Cheung, R; Essex, MN; Pan, S; Salomon, PA | 1 |
| Chinwatanawongwan, B; Chompoonutprapa, P; Laoruengthana, A; Pongpirul, K; Rattanaprichavej, P; Reosanguanwong, K | 1 |
| Cao, S; Hu, J; Li, Y; Liu, F; Liu, Q; Xiong, Z; Zhang, X; Zhou, L | 1 |
| Chen, CF; Chen, WM; Chou, TA; Ma, HH; Tsai, SW; Wang, HY; Wu, PK | 1 |
| Chen, Y; Liu, G; Ma, Y; Tian, X; Yang, Y; Zhuang, Y | 1 |
| Chaibhuddanugul, N; Laoruengthana, A; Malisorn, S; Pongpirul, K; Rattanaprichavej, P; Tangsripong, P | 1 |
| Angthong, C; Manuwong, S; Rajbhandari, P; Singh, V; Veljkovic, A | 1 |
| Ge, WK; Hong, C; Lin, SN; Liu, CJ; Xie, HY; Yu, M | 1 |
3 review(s) available for isoxazoles and morphine
| Article | Year |
|---|---|
Valproate and myoclonus.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Aspartic Acid; Clonazepam; DDT; Disease Models, Animal; Flurazepam; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Light; Morphine; Muscimol; Myoclonus; Serotonin; Urea; Valproic Acid | 1986 |
Pain Relief by Parecoxib for Laparoscopic Cholecystectomy: A Meta-Analysis of Randomized Controlled Trials.
Topics: Cholecystectomy, Laparoscopic; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Morphine; Pain Measurement; Pain, Postoperative; Publication Bias; Randomized Controlled Trials as Topic | 2018 |
The efficacy of parecoxib in improving pain after total knee or total hip arthroplasty: Systematic review and meta-analysis.
Topics: Aged; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Morphine; Nausea; Pain, Postoperative; Vomiting | 2022 |
44 trial(s) available for isoxazoles and morphine
| Article | Year |
|---|---|
Intravenous parecoxib sodium foracute pain after orthopedic knee surgery.
Topics: Aged; Analgesia; Arthroplasty, Replacement, Knee; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Isoxazoles; Ketorolac; Knee Joint; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Sensitivity and Specificity; Treatment Outcome | 2002 |
Efficacy and safety of intravenous parecoxib sodium in relieving acute postoperative pain following gynecologic laparotomy surgery.
Topics: Adult; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Hysterectomy; Injections, Intravenous; Isoxazoles; Ketorolac; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative | 2002 |
Effect of parecoxib, a novel intravenous cyclooxygenase type-2 inhibitor, on the postoperative opioid requirement and quality of pain control.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclooxygenase Inhibitors; Double-Blind Method; Humans; Isoxazoles; Middle Aged; Morphine; Pain, Postoperative | 2002 |
Parecoxib sodium has opioid-sparing effects in patients undergoing total knee arthroplasty under spinal anaesthesia.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anesthesia, Spinal; Arthroplasty, Replacement, Knee; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative; Patient Satisfaction | 2003 |
Parecoxib sodium, a parenteral cyclooxygenase 2 selective inhibitor, improves morphine analgesia and is opioid-sparing following total hip arthroplasty.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Isoenzymes; Isoxazoles; Male; Membrane Proteins; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prostaglandin-Endoperoxide Synthases | 2003 |
Analgesic effects of parecoxib following total abdominal hysterectomy.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hysterectomy; Isoxazoles; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting | 2003 |
Efficacy and safety of the cyclooxygenase 2 inhibitors parecoxib and valdecoxib in patients undergoing coronary artery bypass surgery.
Topics: Administration, Oral; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Coronary Artery Bypass; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Isoenzymes; Isoxazoles; Male; Membrane Proteins; Middle Aged; Morphine; Pain Measurement; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Safety; Sulfonamides | 2003 |
The analgesic effects that underlie patient satisfaction with treatment.
Topics: Adult; Analgesics; Cholecystectomy, Laparoscopic; Double-Blind Method; Drug Administration Routes; Drug Administration Schedule; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Outcome Assessment, Health Care; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Care; Preoperative Care; Prospective Studies; Retrospective Studies; Sex Factors; Sulfonamides; Time Factors | 2004 |
A clinical trial demonstrates the analgesic activity of intravenous parecoxib sodium compared with ketorolac or morphine after gynecologic surgery with laparotomy.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Hysterectomy; Isoxazoles; Ketorolac; Laparotomy; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative | 2004 |
The cyclooxygenase-2-specific inhibitor parecoxib sodium is as effective as 12 mg of morphine administered intramuscularly for treating pain after gynecologic laparotomy surgery.
Topics: Adult; Analgesics, Opioid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Injections, Intramuscular; Isoxazoles; Laparoscopy; Membrane Proteins; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prostaglandin-Endoperoxide Synthases | 2005 |
A randomized, double-blind comparison between parecoxib sodium and propacetamol for parenteral postoperative analgesia after inguinal hernia repair in adult patients.
Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Hernia, Inguinal; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative; Prospective Studies | 2005 |
Single dose parecoxib significantly improves ventilatory function in early extubation coronary artery bypass surgery: a prospective randomized double blind placebo controlled trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Carbon Dioxide; Coronary Artery Bypass; Creatinine; Cyclooxygenase 2 Inhibitors; Device Removal; Double-Blind Method; Drug Administration Schedule; Fluid Therapy; Humans; Intubation, Intratracheal; Isoxazoles; Kidney; Middle Aged; Morphine; Pain, Postoperative; Postoperative Care; Respiration | 2006 |
Safety and efficacy of the cyclooxygenase-2 inhibitors parecoxib and valdecoxib after noncardiac surgery.
Topics: Adult; Aged; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative; Sulfonamides | 2006 |
The associations between severity of early postoperative pain, chronic postsurgical pain and plasma concentration of stable nitric oxide products after breast surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia; Anxiety; Breast Neoplasms; Bupivacaine; Celecoxib; Chronic Disease; Depression; Dextropropoxyphene; Diclofenac; Female; Humans; Isoxazoles; Mastectomy; Middle Aged; Morphine; Nerve Block; Nitric Oxide; Nociceptors; Pain Measurement; Pain, Postoperative; Pyrazoles; Sulfonamides | 2006 |
Cost analysis applied to postoperative analgesia regimens: a comparison between parecoxib and propacetamol.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cost-Benefit Analysis; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Hernia, Inguinal; Humans; Injections, Intravenous; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative; Patient Satisfaction; Prospective Studies | 2007 |
Improving the analgesic efficacy of intrathecal morphine with parecoxib after total abdominal hysterectomy.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hysterectomy; Injections, Intravenous; Injections, Spinal; Isoxazoles; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies; Treatment Outcome | 2007 |
Preventive effects of perioperative parecoxib on post-discectomy pain.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase Inhibitors; Diskectomy; Double-Blind Method; Drug Administration Schedule; Humans; Isoxazoles; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Perioperative Care; Postoperative Care; Preanesthetic Medication; Prospective Studies | 2008 |
Effect of parecoxib on postoperative pain after lumbar spine surgery: a bicenter, randomized, double-blinded, placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclooxygenase Inhibitors; Decompression, Surgical; Diskectomy; Drug Therapy, Combination; Humans; Isoxazoles; Lumbar Vertebrae; Middle Aged; Morphine; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Spinal Fusion; Treatment Outcome | 2008 |
Parecoxib for analgesia after craniotomy.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Craniotomy; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies; Young Adult | 2009 |
Glomerular filtration rate after tramadol, parecoxib and pindolol following anaesthesia and analgesia in comparison with morphine in dogs.
Topics: Analgesics; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Dogs; Glomerular Filtration Rate; Isoxazoles; Morphine; Pindolol; Tramadol | 2009 |
Preincisional versus postincisional administration of parecoxib in colorectal surgery: effect on postoperative pain control and cytokine response. A randomized clinical trial.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Colectomy; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Cytokines; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative | 2010 |
Comparison of the efficacy of parecoxib versus ketorolac combined with morphine on patient-controlled analgesia for post-cesarean delivery pain management.
Topics: Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioid; Cesarean Section; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Humans; Infusions, Intravenous; Isoxazoles; Ketorolac; Morphine; Pain, Postoperative; Pregnancy | 2010 |
[Effects of parecoxib on morphine dosage in postoperative patient-controlled analgesia following thoracoscope-assisted thoracotomy].
Topics: Adult; Aged; Analgesia, Patient-Controlled; Combined Modality Therapy; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative; Thoracoscopy; Thoracotomy; Young Adult | 2011 |
Effect of intravenous parecoxib on post-craniotomy pain.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Anti-Inflammatory Agents, Non-Steroidal; Craniotomy; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Injections, Intravenous; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative | 2011 |
Comparison of preincisional and postincisional parecoxib administration on postoperative pain control and cytokine response after total hip replacement.
Topics: Aged; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Cyclooxygenase 2 Inhibitors; Cytokines; Female; Femur Head Necrosis; Hip Fractures; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative | 2012 |
Effect of perioperative parecoxib on postoperative pain and local inflammation factors PGE2 and IL-6 for total knee arthroplasty: a randomized, double-blind, placebo-controlled study.
Topics: Aged; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Cyclooxygenase 2 Inhibitors; Dinoprostone; Double-Blind Method; Female; Humans; Inflammation; Interleukin-6; Isoxazoles; Knee Joint; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Range of Motion, Articular; Synovial Fluid | 2014 |
Effects of parecoxib on morphine analgesia after gynecology tumor operation: a randomized trial of parecoxib used in postsurgical pain management.
Topics: Adult; Analgesics, Opioid; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Genital Neoplasms, Female; Humans; Isoxazoles; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Treatment Outcome | 2013 |
Comparison of the analgesic effects of cryoanalgesia vs. parecoxib for lung cancer patients after lobectomy.
Topics: Adult; Aged; Analgesia; Cryoanesthesia; Female; Humans; Intercostal Nerves; Isoxazoles; Lung Neoplasms; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Pneumonectomy | 2015 |
Single bolus parecoxib attenuates sore throat after laryngeal microsurgery: a randomized double-blind control study.
Topics: Adult; Female; Humans; Isoxazoles; Larynx; Male; Microsurgery; Middle Aged; Morphine; Patient Satisfaction; Pharyngitis; Postoperative Complications | 2014 |
Effects of parecoxib on analgesia benefit and blood loss following open prostatectomy: a multicentre randomized trial.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Therapy, Combination; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Hemorrhage; Prostatectomy | 2015 |
Effect of cyclooxygenase-2-specific inhibitors on postoperative analgesia after major open abdominal surgery.
Topics: Abdomen; Analgesia, Patient-Controlled; Analgesics, Opioid; Analysis of Variance; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies; Tramadol | 2015 |
Effect of Parecoxib as an Adjunct to Patient-Controlled Epidural Analgesia after Abdominal Hysterectomy: A Multicenter, Randomized, Placebo-Controlled Trial.
Topics: Adolescent; Adult; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Hysterectomy; Isoxazoles; Middle Aged; Morphine; Pain Management; Pain, Postoperative; Ropivacaine; Young Adult | 2016 |
Parecoxib, propacetamol, and their combination for analgesia after total hip arthroplasty: a randomized non-inferiority trial.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Arthroplasty, Replacement, Hip; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Recovery of Function | 2017 |
Parecoxib Supplementation to Morphine Analgesia Decreases Incidence of Delirium in Elderly Patients After Hip or Knee Replacement Surgery: A Randomized Controlled Trial.
Topics: Administration, Intravenous; Age Factors; Aged; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; China; Cyclooxygenase 2 Inhibitors; Delirium; Double-Blind Method; Female; Humans; Incidence; Intention to Treat Analysis; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome | 2017 |
[EFFICACY OF SEQUENTIAL TREATMENT WITH ADDUCTOR CANAL NERVE BLOCK AND CYCLOOXYGENASE 2 SELECTIVE INHIBITOR AFTER TOTAL KNEE ARTHROPLASTY].
Topics: Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Knee Joint; Morphine; Nerve Block; Operative Time; Osteoarthritis; Pain, Postoperative; Postoperative Period; Range of Motion, Articular; Treatment Outcome | 2016 |
Role of Parecoxib Sodium in the Multimodal Analgesia after Total Knee Arthroplasty: A Randomized Double-blinded Controlled Trial.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoxazoles; Knee Joint; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Range of Motion, Articular | 2018 |
Pain Management Using Perioperative Administration of Parecoxib for Total Hip Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Prospective Studies | 2019 |
Parecoxib in laparoscopic surgery for simple vesicular lithiasis.
Topics: Adult; Analgesia; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Combined Modality Therapy; Double-Blind Method; Female; Humans; Isoxazoles; Lithiasis; Male; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Recovery Room; Tunisia; Urinary Bladder Calculi | 2019 |
The relationship between postoperative opioid consumption and the incidence of hypoxemic events following total hip arthroplasty: a post hoc analysis.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Hypoxia; Incidence; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Switzerland; Treatment Outcome | 2020 |
A randomized controlled trial comparing the efficacies of ketorolac and parecoxib for early pain management after total knee arthroplasty.
Topics: Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Blood Transfusion; Bupivacaine; Drug Therapy, Combination; Drug Utilization; Female; Humans; Injections, Intra-Articular; Isoxazoles; Ketorolac; Male; Middle Aged; Morphine; Pain, Postoperative; Prospective Studies; Visual Analog Scale | 2020 |
Intraoperative periarticular injection can alleviate the inflammatory response and enhance joint function recovery after hip arthroplasty in elderly patients with osteoporotic femoral neck fractures.
Topics: Aged; Arthroplasty, Replacement, Hip; Betamethasone; Biomarkers; Drug Therapy, Combination; Epinephrine; Female; Femoral Neck Fractures; Humans; Inflammation Mediators; Injections, Intra-Articular; Intraoperative Care; Isoxazoles; Male; Morphine; Osteoporotic Fractures; Postoperative Complications; Recovery of Function; Ropivacaine | 2021 |
An opioid-sparing protocol with intravenous parecoxib can effectively reduce morphine consumption after simultaneous bilateral total knee arthroplasty.
Topics: Administration, Intravenous; Aged; Arthroplasty, Replacement, Knee; Female; Humans; Isoxazoles; Knee Joint; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities; Postoperative Period; Prospective Studies; Range of Motion, Articular; Treatment Outcome; Visual Analog Scale | 2021 |
Effects of parecoxib after pancreaticoduodenectomy: A single center randomized controlled trial.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Pancreaticoduodenectomy | 2021 |
Efficacy of intravenous perioperative parecoxib administration in the surgical fixation of unstable ankle fracture: a prospective, double-blinded, randomized, placebo-controlled trial.
Topics: Ankle Fractures; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Injections, Intravenous; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Prospective Studies | 2021 |
39 other study(ies) available for isoxazoles and morphine
| Article | Year |
|---|---|
Mechanisms by which diazepam, muscimol, and other drugs change the content of cGMP in cerebellar cortex.
Topics: Alkaloids; Animals; Cerebellar Cortex; Cyclic GMP; Diazepam; Haloperidol; Harmaline; Isoxazoles; Male; Morphine; Oxazoles; Purkinje Cells; Pyridines; Rats | 1977 |
GABA in the ventral tegmental area: differential regional effects on locomotion, aggression and food intake after microinjection of GABA agonists and antagonists.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Bicuculline; Carbachol; Cerebral Cortex; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Haloperidol; Humans; Isoxazoles; Male; Methyltyrosines; Morphine; Motor Activity; Muscimol; Picrotoxin; Rats; Reserpine | 1979 |
Muscimol antagonizes morphine hypermotility without potentiation of analgesia.
Topics: Analgesia; Analgesics; Animals; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Neuromuscular Blocking Agents; Oxazoles | 1978 |
Potentiation of morphine analgesia by muscimol.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Drug Synergism; Isoxazoles; Mice; Morphine; Oxazoles; Quaternary Ammonium Compounds; Rats | 1977 |
Role of calcium in the analgesic action of tetrahydroisoxazolepyridinol and muscimol.
Topics: Analgesics; Animals; Calcium; Calcium Chloride; Isoxazoles; Male; Mice; Morphine; Muscimol; Nifedipine | 1991 |
Tolerance pattern to GABAmimetic analgesics and their influence on morphine tolerance and dependence.
Topics: Analgesics; Animals; Drug Interactions; Drug Tolerance; Isoxazoles; Male; Mice; Morphine; Muscimol; Naloxone; Substance-Related Disorders | 1991 |
Role of GABAergic system in prolactin analgesia.
Topics: Analgesics; Animals; Bicuculline; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Morphine; Prolactin | 1989 |
GABAergic involvement in the antinociceptive effects of morphine at the level of the periaqueductal gray matter in the rat.
Topics: Animals; Isoxazoles; Male; Morphine; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
The parafasciculus thalami as a site for mediating the antinociceptive response to GABAergic drugs.
Topics: Animals; gamma-Aminobutyric Acid; Isoxazoles; Male; Morphine; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Synaptic Transmission; Thalamic Nuclei | 1986 |
GABAergic modulation of the analgesic effects of morphine microinjected in the ventral periaqueductal gray matter of the rat.
Topics: Animals; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Morphine; Neurons; Nociceptors; Oxazoles; Periaqueductal Gray; Picrotoxin; Raphe Nuclei; Rats; Rats, Inbred Strains | 1987 |
An antinociceptive profile of kojic amine: an analogue of gamma-aminobutyric acid (GABA).
Topics: Animals; Atropine; Atropine Derivatives; Baclofen; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Morphine; Motor Activity; Pain; Pyrans; Pyrones | 1987 |
The effect of mouse spinal cord transection on the antinociceptive response to the gamma-aminobutyric acid agonists THIP (4,5,6,7-tetrahydroisoxazolo [5,4-c]pyridine-3-ol) and baclofen.
Topics: Analgesics; Animals; Baclofen; Central Nervous System; Clonidine; Cordotomy; Isoxazoles; Male; Mice; Morphine; Oxazoles; Oxotremorine | 1985 |
Shock titration in the rhesus monkey: effects of opiate and nonopiate analgesics.
Topics: Administration, Oral; Analgesics; Animals; Aspirin; Codeine; Diazepam; Dose-Response Relationship, Drug; Electroshock; Ibuprofen; Injections, Intramuscular; Isoxazoles; Male; Morphine; Narcotics; Reaction Time; Sensory Thresholds; Time Factors | 1985 |
Antinociceptive effect of the GABAmimetic 4,5,6,7-tetrahydroisoxazolo [5, 4-c]pyridin-3-ol (THIP): chronic treatment increases alpha-2 adrenoceptors in the mouse brain.
Topics: Analgesics; Animals; Brain Chemistry; Clonidine; Drug Tolerance; Isoxazoles; Male; Mice; Mice, Inbred Strains; Morphine; Oxazoles; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Microiontophoretically applied THIP effects upon nociceptive responses of neurons in medial thalamus.
Topics: Animals; Evoked Potentials; gamma-Aminobutyric Acid; Isoxazoles; Male; Morphine; Neurons; Nociceptors; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Spinothalamic Tracts; Synaptic Transmission; Tail; Thalamic Nuclei | 1983 |
Anorexic and analgesic actions of THIP.
Topics: Analgesics; Animals; Appetite Depressants; Behavior, Animal; Benzoquinones; Drug Interactions; Feeding Behavior; Isoxazoles; Male; Mice; Morphine; Oxazoles; Quinones; Rats; Rats, Inbred Strains; Reaction Time | 1983 |
Comparison of the analgesic actions of THIP and morphine.
Topics: Analgesics; Animals; Atropine; Benzoquinones; Bicuculline; Hypnotics and Sedatives; Isoxazoles; Male; Mice; Morphine; Naloxone; Oxazoles; Quinones; Reaction Time | 1983 |
THIP analgesia: cross tolerance with morphine.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Isoxazoles; Male; Mice; Models, Biological; Morphine; Nipecotic Acids; Oxazoles; Pyrones | 1983 |
A comparison of the analgesic activities of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP) and 6-chloro-2[1-piperazinyl]pyrazine (MK 212).
Topics: Analgesics; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Isoxazoles; Male; Mice; Morphine; Oxazoles; Pyrazines; Time Factors | 1983 |
Effects of GABA analogues and their interactions with morphine on locomotor activity in two inbred strains of mice.
Topics: Animals; Drug Interactions; gamma-Aminobutyric Acid; Isoxazoles; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Motor Activity; Muscimol; Piracetam | 1982 |
Differentiation of the analgesic effects of THIP and morphine using three mouse strains.
Topics: Analgesics; Animals; GABA Antagonists; Hot Temperature; Isoxazoles; Male; Mice; Mice, Inbred Strains; Morphine; Oxazoles | 1982 |
Comparison of the antinociceptive actions of THIP and morphine.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Isoxazoles; Male; Mice; Mice, Inbred Strains; Morphine; Oxazoles; Reaction Time; Species Specificity | 1982 |
Antinociceptive and anticonvulsive effect of THIP, a pure GABA agonist.
Topics: Analgesics; Animals; Anticonvulsants; Benzoquinones; gamma-Aminobutyric Acid; Injections, Intraventricular; Isoxazoles; Mice; Morphine; Oxazoles; Quinones; Rats; Rats, Inbred Strains; Reaction Time | 1982 |
Analgesic properties of the GABA-mimetic THIP.
Topics: Analgesics; Animals; Arthritis, Experimental; Baclofen; Electric Stimulation; Isoxazoles; Macaca mulatta; Mice; Morphine; Muscimol; Oxazoles; Reaction Time | 1981 |
A study on the role of cholinergic and gamma amino butyric acid systems in the anti-nociceptive effect of gossypin.
Topics: Analgesics; Animals; Flavonoids; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Morphine; Pain Measurement; Parasympathetic Nervous System; Parasympathomimetics | 1993 |
Effects of CCK antagonists on GABA mechanism-induced antinociception in the formalin test.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Baclofen; Dose-Response Relationship, Drug; Formaldehyde; GABA Agents; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Isoxazoles; Male; Mice; Morphine; Pain; Pain Measurement; Receptors, Cholecystokinin | 1999 |
Inhibition of THIP on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity.
Topics: Animals; Drug Tolerance; GABA Agonists; GABA-A Receptor Agonists; Isoxazoles; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Receptors, Dopamine | 2002 |
Reporting of clinical trials of analgesia.
Topics: Analgesia; Analgesia, Patient-Controlled; Clinical Trials as Topic; Coronary Artery Bypass; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Isoxazoles; Membrane Proteins; Morphine; Prostaglandin-Endoperoxide Synthases; Sulfonamides | 2004 |
Parecoxib: new preparation. A NSAID for postoperative pain: no proven advantage.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Canada; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Drug Approval; Europe; Follow-Up Studies; Humans; Isoxazoles; Morphine; Pain, Postoperative; United States | 2004 |
Involvement of GABAergic modulation of antinociception induced by morphine microinjected into the ventrolateral orbital cortex.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Microinjections; Morphine; Muscimol; Narcotics; Neurons; Nociceptors; Pain Measurement; Picrotoxin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time | 2006 |
The importance of genetic background on pain behaviours and pharmacological sensitivity in the rat spared serve injury model of peripheral neuropathic pain.
Topics: Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Isoxazoles; Male; Morphine; Neuralgia; Pain Measurement; Pain Threshold; Peripheral Nerve Injuries; Pharmacogenetics; Rats; Rats, Inbred BN; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Reproducibility of Results; Species Specificity | 2007 |
Electroencephalographic responses of tramadol, parecoxib and morphine to acute noxious electrical stimulation in anaesthetised dogs.
Topics: Analgesics; Anesthesia; Animals; Cyclooxygenase 2 Inhibitors; Dogs; Dose-Response Relationship, Drug; Drug Evaluation; Electric Stimulation; Electrocardiography; Electroencephalography; Female; Heart Rate; Isoxazoles; Male; Morphine; Narcotics; Tramadol | 2010 |
Multimodal pain management following minimally invasive total knee arthroplasty: an experience in 3-dose parecoxib.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Combined Modality Therapy; Cyclooxygenase 2 Inhibitors; Female; Humans; Injections, Intravenous; Isoxazoles; Male; Middle Aged; Minimally Invasive Surgical Procedures; Morphine; Pain Measurement; Pain, Postoperative; Recovery of Function; Treatment Outcome | 2009 |
Interactions of the potent D-amino acid oxidase inhibitor CBIO with morphine in pain and tolerance to analgesia.
Topics: Analgesics, Opioid; Animals; D-Amino-Acid Oxidase; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Injections, Spinal; Injections, Subcutaneous; Isoxazoles; Male; Mice; Morphine; N-Methylaspartate; Pain; Pain Measurement; Reaction Time; Receptors, N-Methyl-D-Aspartate | 2012 |
Contributions of spinal D-amino acid oxidase to bone cancer pain.
Topics: Analgesia; Analgesics, Opioid; Animals; Astrocytes; Bone Neoplasms; Carcinoma 256, Walker; D-Amino-Acid Oxidase; Enzyme Inhibitors; Female; Gene Expression; Hyperalgesia; Injections, Spinal; Isoxazoles; Morphine; Nerve Tissue Proteins; Pain; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Opioid, mu; Spinal Cord; Tibia | 2012 |
[Economic analysis of parecoxib in the management of postsurgical pain in gynecology].
Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Costs and Cost Analysis; Decision Trees; Female; Gynecologic Surgical Procedures; Humans; Isoxazoles; Ketorolac; Morphine; Pain, Postoperative | 2012 |
Zonisamide: Antihyperalgesic efficacy, the role of serotonergic receptors on efficacy in a rat model for painful diabetic neuropathy.
Topics: Animals; Anticonvulsants; Carbamazepine; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Isoxazoles; Ketanserin; Male; Morphine; Ondansetron; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT3; Streptozocin; Zonisamide | 2014 |
Transitional Study of Patient-Controlled Analgesia Morphine With Ketorolac to Patient-Controlled Analgesia Morphine With Parecoxib Among Donors in Adult Living Donor Liver Transplantation: A Single-Center Experience.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Humans; Isoxazoles; Ketorolac; Liver Transplantation; Living Donors; Male; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Retrospective Studies; Tissue and Organ Harvesting | 2016 |
Perioperative Outcomes of Patients Who Were Not Candidates for Additional Nonsteroidal Anti-inflammatory Drugs in a Multimodal Pain Control Regimen for Total Knee Arthroplasty.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Retrospective Studies | 2021 |