isoxazoles has been researched along with cysteine in 52 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (19.23) | 18.7374 |
1990's | 19 (36.54) | 18.2507 |
2000's | 16 (30.77) | 29.6817 |
2010's | 7 (13.46) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Ballatori, N; Dutczak, WJ | 1 |
Grotyohann, LW; Scaduto, RC | 1 |
Brown, PI; Nicoll, DW; Rankin, GO; Shih, HC; Teets, VJ; Yang, DJ | 1 |
Israel, Y; Shackel, N; Speisky, H; Varghese, G; Wade, D | 1 |
Grotyohann, LW; Martin, LF; Scaduto, RC; Slusser, SO | 1 |
Armario, A; Garvey, JS; Hidalgo, J | 1 |
Elliott, WL; Jayaram, HN; Lui, MS; Pillwein, K; Plowman, J; Reardon, MA; Weber, G | 1 |
Anderson, ME; Bridges, RJ; Meister, A; Underwood, M | 1 |
Hirayama, K; Inoue, M; Yasutake, A | 1 |
Burk, RF; Hill, KE; Von Hoff, DD | 1 |
Mego, JL | 1 |
Anders, MW; Elfarra, AA; Jakobson, I | 1 |
Meredith, MJ; Williams, GM | 1 |
Anders, MW; Lash, LH | 1 |
Hayden, P; Stevens, J; Taylor, G | 1 |
Griffith, OW; Meister, A | 1 |
Bernström, K; Hammarström, S; Orning, L | 1 |
Lou, L; Nakamura, J; Straub, K; Wu, J | 1 |
Horiba, M; Kohno, S; Nabe, T; Ohata, K; Saeki, Y; Tanpo, T; Yamamura, H | 1 |
Harada, T; Hiraishi, H; Ivey, KJ; Mutoh, H; Ota, S; Razandi, M; Sugimoto, T; Terano, A | 1 |
Anderson, M; Burt, ME; Harrison, LE; Hochwald, SN; Rose, DM | 1 |
Dekker, EE; Johnson, AR | 1 |
Li, X; Orwar, O; Revesjö, C; Sandberg, M | 1 |
Bustos, P; Cardemil, E; Gajardo, MI; Goldie, H; Gómez, C; Jabalquinto, AM | 1 |
Raymond, MN; Robin, P; Rossignol, B | 1 |
Beers, K; Bottje, WG; Cawthon, D; Evenson, C; McNew, R; Wang, S | 1 |
Dringen, R; Hamprecht, B; Pfeiffer, B | 1 |
Li, X; Sandberg, M; Wallin, C; Weber, SG | 1 |
Chien, KC; Inoue, M; Kasahara, E; Kashiba, M | 1 |
Feelisch, M; Grisham, MB; Hallén, K; Jourd'heuil, D | 1 |
Barfuss, DW; Cannon, VT; Zalups, RK | 1 |
Dahm, LJ; Jones, DP | 1 |
Gaston, B; Gozal, D; Johnson, MA; Lieberman, MW; Lipton, AJ; Macdonald, T | 1 |
Bandeira-Melo, C; Hall, JC; Penrose, JF; Weller, PF | 1 |
Accatino, L; Arrese, M; Koenig, CS; Pizarro, M; Solís, N | 1 |
Hedley, DW; Ruoso, P | 1 |
Hultberg, B; Hultberg, M | 1 |
Bruno, MK; Cohen, SD; Hill, DW; Horton, RA; Roberts, JC; Stern, ST | 1 |
Kawabata, D; Mimori, T | 1 |
Amrhein, N; Fitzpatrick, TB; Raschle, T | 1 |
Matsuda, T; Ohtsubo, H | 1 |
Bewley, CA; Fetterolf, BJ; Gutierrez-Lugo, MT; Metaferia, BB; Moravec, M; Ray, S; Shazad-Ul-Hussan, S; Smith, JA | 1 |
Saito, E; Suwa, A; Suzuki, Y; Wakabayashi, T | 1 |
Yamanaka, H | 1 |
Mimori, T; Yukawa, N | 1 |
Coppo, L; Di Giuseppe, D; Di Simplicio, P; Frosali, S; Heo, J; Margaritis, A; Priora, R; Summa, D | 1 |
Ichikawa, N; Yamanaka, H | 1 |
Horenstein, NA; Papke, RL; Stokes, C; Wang, J | 1 |
Barfuss, DW; Wang, Y; Zalups, RK | 1 |
Arvidsson, PI; Besidski, Y; Bueters, T; Bylund, J; Macsari, I; Olofsson, S; Petersson, C | 1 |
Suzuki, Y | 1 |
Brindisi, M; Ghosh, AK; Ghosh, K; Huang, X; Kumaragurubaran, N; Lendy, EK; Mesecar, AD; Tang, J; Yen, YC | 1 |
6 review(s) available for isoxazoles and cysteine
Article | Year |
---|---|
[Disease modifying anti-rheumatic drugs (DMARDs): an overview].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Benzopyrans; Cysteine; Evidence-Based Medicine; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Meta-Analysis as Topic; Methotrexate; Randomized Controlled Trials as Topic; Sulfasalazine; Sulfonamides | 2005 |
[Effective combination therapy of TNF antagonists with DMARDs].
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Cysteine; Drug Therapy, Combination; Etanercept; Humans; Hydroxychloroquine; Immunoglobulin G; Infliximab; Isoxazoles; Leflunomide; Methotrexate; Receptors, Tumor Necrosis Factor; Sulfasalazine; Tumor Necrosis Factor-alpha | 2007 |
[Adverse effects of conventional DMARDs and biologic DMARDs].
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Eruptions; Drug Hypersensitivity; Hematologic Diseases; Humans; Immune System Diseases; Infliximab; Isoxazoles; Kidney Diseases; Leflunomide; Lung Diseases; Methotrexate | 2007 |
[Antirheumatic agents for treatment of rheumatoid arthritis].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Methotrexate; Pharmacogenetics; Randomized Controlled Trials as Topic; Remission Induction; Sulfasalazine; Time Factors | 2008 |
[Effect of disease modifying anti-rheumatic drugs on radiographic progression in rheumatoid arthritis].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Cysteine; Disease Progression; Drug Therapy, Combination; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Methotrexate; Penicillamine; Radiography; Randomized Controlled Trials as Topic; Sulfasalazine; Tacrolimus | 2009 |
[ Bone and cartilage destruction in RA and its intervention. Disease-modifying antirheumatic drugs].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone and Bones; Cartilage; Clinical Trials as Topic; Cysteine; Humans; Isoxazoles; Joints; Leflunomide; Methotrexate; Sulfasalazine; Tacrolimus | 2012 |
46 other study(ies) available for isoxazoles and cysteine
Article | Year |
---|---|
gamma-Glutamyltransferase-dependent biliary-hepatic recycling of methyl mercury in the guinea pig.
Topics: Animals; Bile; Cysteine; gamma-Glutamyltransferase; Glutathione; Guinea Pigs; Isoxazoles; Liver; Male; Methylmercury Compounds | 1992 |
Cysteine oxidation by the postischemic rat kidney.
Topics: Animals; Cysteine; Glutathione; Iron; Ischemia; Isoxazoles; Kidney; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains; Renal Circulation | 1992 |
N-(3,5-dichlorophenyl)succinimide nephrotoxicity: evidence against the formation of nephrotoxic glutathione or cysteine conjugates.
Topics: Aminooxyacetic Acid; Animals; Biotransformation; Cysteine; Fungicides, Industrial; gamma-Glutamyltransferase; Glutathione; In Vitro Techniques; Isoxazoles; Kidney Diseases; Male; Rats; Rats, Inbred F344; Succinimides | 1991 |
Role of hepatic gamma-glutamyltransferase in the degradation of circulating glutathione: studies in the intact guinea pig perfused liver.
Topics: Animals; Borates; Cysteine; Dipeptides; gamma-Glutamyltransferase; Glutathione; Guinea Pigs; Isoxazoles; Liver; Perfusion; Serine | 1990 |
Glutathione catabolism by the ischemic rat kidney.
Topics: Acetylcysteine; Animals; Antimetabolites; Cysteine; gamma-Glutamyltransferase; Glutathione; Ischemia; Isoxazoles; Kidney; Male; Rats; Reperfusion; Sulfhydryl Compounds | 1990 |
On the metallothionein, glutathione and cysteine relationship in rat liver.
Topics: Animals; Body Weight; Buthionine Sulfoximine; Cysteine; Glutathione; Isoxazoles; Liver; Male; Metallothionein; Methionine Sulfoximine; Organ Size; Rats; Rats, Inbred Strains; Starvation; Stress, Physiological; Zinc | 1990 |
Oncolytic activity and mechanism of action of a novel L-cysteine derivative, L-cysteine, ethyl ester, S-(N-methylcarbamate) monohydrochloride.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carbamates; Cattle; Cysteine; Drug Screening Assays, Antitumor; Glutamates; Glutamine; Humans; Isoxazoles; Mice; Neoplasm Transplantation; Rats | 1990 |
Glutathione metabolism at the blood-cerebrospinal fluid barrier.
Topics: Animals; Antimetabolites; Biological Transport; Blood-Brain Barrier; Buthionine Sulfoximine; Choroid Plexus; Cysteine; Dipeptides; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Male; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1989 |
Mechanism of urinary excretion of methylmercury in mice.
Topics: Animals; Antimetabolites; Cysteine; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Male; Methylmercury Compounds; Mice; Mice, Inbred C57BL | 1989 |
Effect of inhibition of gamma-glutamyltranspeptidase by AT-125 (acivicin) on glutathione and cysteine levels in rat brain and plasma.
Topics: Animals; Antibiotics, Antineoplastic; Brain; Cysteine; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Male; Oxazoles; Rats; Rats, Inbred Strains | 1985 |
Stimulation of intralysosomal proteolysis by cysteinyl-glycine, a product of the action of gamma-glutamyl transpeptidase on glutathione.
Topics: Animals; Borates; Cysteine; Dipeptides; Enzyme Activation; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Kidney; Liver; Lysosomes; Mice; Peptide Hydrolases; Rats; Serine | 1985 |
Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity.
Topics: Aminooxyacetic Acid; Animals; Blood Urea Nitrogen; Carbon-Sulfur Lyases; Cysteine; gamma-Glutamyltransferase; Glutathione; Glycosuria; Isoxazoles; Kidney; Liver; Lyases; Male; Mitochondria; Probenecid; Rats; Rats, Inbred F344; Subcellular Fractions | 1986 |
Intracellular glutathione cycling by gamma-glutamyl transpeptidase in tumorigenic and nontumorigenic cultured rat liver cells.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Cysteine; Cystine; gamma-Glutamyltransferase; Glutathione; Half-Life; Isoxazoles; Kinetics; Liver; Liver Neoplasms, Experimental; Rats | 1986 |
Cytotoxicity of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine in isolated rat kidney cells.
Topics: Adenine Nucleotides; Aminooxyacetic Acid; Aminopeptidases; Animals; CD13 Antigens; Cell Survival; Cysteine; Dipeptides; Dose-Response Relationship, Drug; Glutathione; Glycylglycine; Isoxazoles; Kidney Tubules, Proximal; Male; Oxygen Consumption; Phenanthrolines; Rats; Rats, Inbred F344; Time Factors | 1986 |
The role of glutathione conjugate metabolism and cysteine conjugate beta-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells.
Topics: Acetylcysteine; Aminooxyacetic Acid; Animals; Carbon-Sulfur Lyases; Cell Line; Cell Survival; Cysteine; Glutathione; Isoxazoles; Kidney Tubules, Proximal; Lyases; Microscopy, Electron; Pyruvates; Pyruvic Acid; Structure-Activity Relationship; Swine | 1986 |
Excretion of cysteine and gamma-glutamylcysteine moieties in human and experimental animal gamma-glutamyl transpeptidase deficiency.
Topics: Animals; Autoanalysis; Biological Transport; Cysteine; Dipeptides; Disulfides; gamma-Glutamyltransferase; Glutamates; Glutathione; Glutathione Reductase; Glycine; Humans; Isoxazoles; Male; Mice | 1980 |
Formation of leukotrienes E3, E4 and E5 in rat basophilic leukemia cells.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Basophils; Calcimycin; Chromatography, High Pressure Liquid; Cysteine; Glycine; Isoxazoles; Leukemia, Experimental; Leukotriene E4; Rats; SRS-A | 1981 |
The glutamine hydrolysis function of human GMP synthetase. Identification of an essential active site cysteine.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Carbon-Nitrogen Ligases; Cysteine; Enzyme Inhibitors; Glutamine; Guanosine Monophosphate; Humans; Hydrolysis; In Vitro Techniques; Isoxazoles; Kinetics; Ligases; Molecular Sequence Data; Peptide Fragments | 1995 |
Inhibitory effect of ONO-1078 on specific binding of peptide leukotrienes to human lung crude membrane.
Topics: Cell Membrane; Chromones; Cysteine; gamma-Glutamyltransferase; Glycine; Humans; Isoxazoles; Leukotriene D4; Lung; Protein Binding; SRS-A | 1994 |
Protection of cultured rat gastric cells against oxidant-induced damage by exogenous glutathione.
Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Chromium Radioisotopes; Cysteine; Dose-Response Relationship, Drug; Female; gamma-Glutamyltransferase; Glucose; Glucose Oxidase; Glutamate-Cysteine Ligase; Glutathione; Hydrogen Peroxide; Isoxazoles; Male; Methionine Sulfoximine; Protein Precursors; Rats; Rats, Sprague-Dawley; Resting Phase, Cell Cycle; Stomach | 1994 |
gamma-Glutamyl transpeptidase mediation of tumor glutathione utilization in vivo.
Topics: Animals; Cysteine; Enzyme Inhibitors; Female; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Methylcholanthrene; Rats; Rats, Inbred F344; Sarcoma, Experimental | 1996 |
Woodward's reagent K inactivation of Escherichia coli L-threonine dehydrogenase: increased absorbance at 340-350 nm is due to modification of cysteine and histidine residues, not aspartate or glutamate carboxyl groups.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Cysteine; Enzyme Inhibitors; Escherichia coli; Glutamic Acid; Histidine; Isoxazoles; Kinetics; Models, Chemical; Molecular Sequence Data; Solvents; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1996 |
Gamma-glutamyl peptides and related amino acids in rat hippocampus in vitro: effect of depolarization and gamma-glutamyl transpeptidase inhibition.
Topics: Amino Acids; Animals; Aspartic Acid; Cysteine; Dipeptides; Enzyme Inhibitors; Female; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Glutamine; Glutathione; Hippocampus; Isoxazoles; Male; Rats; Rats, Sprague-Dawley | 1996 |
Woodward's reagent K reacts with histidine and cysteine residues in Escherichia coli and Saccharomyces cerevisiae phosphoenolpyruvate carboxykinases.
Topics: Amino Acids; Binding Sites; Cysteine; Escherichia coli; Histidine; Indicators and Reagents; Isoxazoles; Kinetics; Phosphoenolpyruvate Carboxykinase (GTP); Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet | 1996 |
Detoxification mechanism in the rat extraorbital lacrimal gland: conjugation of brefeldin A to glutathione.
Topics: Animals; Brefeldin A; Chromatography, High Pressure Liquid; Cyclopentanes; Cysteine; Enzyme Inhibitors; Glutathione; Inactivation, Metabolic; Isoxazoles; Lacrimal Apparatus; Male; Rats; Rats, Sprague-Dawley | 1997 |
Hepatic export of glutathione and uptake of constituent amino acids, glutamate and cysteine, in broilers in vivo.
Topics: Animals; Biological Transport; Carotid Arteries; Chickens; Cysteine; Cystine; Dipeptides; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutamic Acid; Glutathione; Hepatic Veins; Isoxazoles; Liver; Male; Portal Vein | 1998 |
Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione.
Topics: Animals; Antioxidants; Astrocytes; Cell Survival; Cells, Cultured; Coculture Techniques; Cysteine; Dipeptides; gamma-Glutamyltransferase; Glutamine; Glutathione; Glycine; Isoxazoles; Neurons; Rats; Rats, Wistar | 1999 |
Net efflux of cysteine, glutathione and related metabolites from rat hippocampal slices during oxygen/glucose deprivation: dependence on gamma-glutamyl transpeptidase.
Topics: Animals; Brain Chemistry; Cell Hypoxia; Cysteine; Enzyme Inhibitors; Extracellular Space; Female; gamma-Glutamyltransferase; Glucose; Glutathione; Hippocampus; Isoxazoles; Male; Organ Culture Techniques; Oxygen; Rats; Rats, Sprague-Dawley | 1999 |
Fates and vascular action of S-nitrosoglutathione and related compounds in the circulation.
Topics: Acetylcysteine; Animals; Blood Pressure; Cysteine; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Male; Nitric Oxide; Nitroso Compounds; Rats; Rats, Wistar; S-Nitrosoglutathione; S-Nitrosothiols | 1999 |
Dynamic state of S-nitrosothiols in human plasma and whole blood.
Topics: Allopurinol; Biotransformation; Chelating Agents; Chlorides; Chromatography, High Pressure Liquid; Cysteine; Enzyme Inhibitors; Glutathione; Humans; Isoxazoles; Mercaptoethanol; Nitroso Compounds; Plasma; S-Nitrosoglutathione; S-Nitrosothiols; Serum Albumin; Zinc Compounds | 2000 |
Molecular homology and the luminal transport of Hg2+ in the renal proximal tubule.
Topics: Animals; Cilastatin; Cysteine; Dipeptidases; Enzyme Inhibitors; Female; gamma-Glutamyltransferase; Glutathione; In Vitro Techniques; Isoxazoles; Kidney Tubules, Proximal; Mercury; Protease Inhibitors; Rabbits; Sequence Homology, Amino Acid | 2000 |
Rat jejunum controls luminal thiol-disulfide redox.
Topics: Analysis of Variance; Animals; Cysteine; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; Glutathione Disulfide; Isoxazoles; Jejunum; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2000 |
S-nitrosothiols signal the ventilatory response to hypoxia.
Topics: Animals; Cell Hypoxia; Cysteine; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Mice; Nitroso Compounds; Oxygen; Rats; Respiratory Physiological Phenomena; S-Nitrosoglutathione; S-Nitrosothiols; Solitary Nucleus; Sulfhydryl Compounds | 2001 |
Cysteinyl leukotrienes induce IL-4 release from cord blood-derived human eosinophils.
Topics: Acetophenones; Animals; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Eosinophils; Fetal Blood; Humans; Immunohistochemistry; Inflammation Mediators; Interleukin-4; Isoxazoles; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Membrane Proteins; Microscopy, Fluorescence; Pertussis Toxin; Propionates; Quinolines; Rabbits; Receptors, Leukotriene; Tetrazoles; Time Factors; Virulence Factors, Bordetella | 2002 |
Bile secretory function after warm hepatic ischemia-reperfusion injury in the rat.
Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Cysteine; Disease Models, Animal; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Isoxazoles; Liver; Male; Mitochondrial Proteins; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Ribosomal Proteins; Saccharomyces cerevisiae Proteins | 2003 |
Inhibition of gamma-glutamyl transpeptidase activity decreases intracellular cysteine levels in cervical carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cysteine; Enzyme Inhibitors; Female; gamma-Glutamyltransferase; Humans; Isoxazoles; Mice; Mice, SCID; Transplantation, Heterologous; Uterine Cervical Neoplasms | 2004 |
High glutathione turnover in human cell lines revealed by acivicin inhibition of gamma-glutamyltranspeptidase and the effects of thiol-reactive metals during acivicin inhibition.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cysteine; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; HeLa Cells; Humans; Isoxazoles; Liver Neoplasms; Metals; Sulfhydryl Compounds | 2004 |
Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity II. Possible involvement of the gamma-glutamyl cycle.
Topics: Acetaminophen; Animals; Cell Membrane; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Glutathione; Glutathione Transferase; Injections, Intraperitoneal; Isoxazoles; Kidney Diseases; Kidney Tubules, Proximal; Male; Mass Spectrometry; Mice; Mice, Inbred Strains; Microvilli; Molecular Structure; Toxicity Tests | 2005 |
On the two components of pyridoxal 5'-phosphate synthase from Bacillus subtilis.
Topics: Antioxidants; Bacillus subtilis; Binding Sites; Carbon-Nitrogen Lyases; Chromatography; Chromatography, Gel; Chromatography, High Pressure Liquid; Cloning, Molecular; Cysteine; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Glutaminase; Glutamine; Immunochemistry; Isoxazoles; Kinetics; Mass Spectrometry; Models, Chemical; Organophosphates; Oxidoreductases; Pentosephosphates; Protein Structure, Tertiary; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry; Threonine; Time Factors; Ultraviolet Rays; Vitamin B 6 | 2005 |
Synthesis of natural product-inspired inhibitors of Mycobacterium tuberculosis mycothiol-associated enzymes: the first inhibitors of GlcNAc-Ins deacetylase.
Topics: Amidohydrolases; Bacterial Proteins; Binding Sites; Cysteine; Furans; Glycopeptides; Inositol; Isoxazoles; Models, Molecular; Mycobacterium tuberculosis; Oxazines; Oxazoles; Protein Binding; Pyrans; Stereoisomerism; Sulfonamides; Thioglycosides | 2007 |
The control of S-thiolation by cysteine via gamma-glutamyltranspeptidase and thiol exchanges in erythrocytes and plasma of diamide-treated rats.
Topics: Animals; Cysteine; Diamide; Enzyme Inhibitors; Erythrocytes; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Kidney; Liver; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Sulfhydryl Reagents; Time Factors | 2010 |
Potential state-selective hydrogen bond formation can modulate activation and desensitization of the α7 nicotinic acetylcholine receptor.
Topics: Allosteric Site; alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Cloning, Molecular; Cysteine; Dose-Response Relationship, Drug; Electrophysiology; Humans; Hydrogen Bonding; Isoxazoles; Ligands; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Mutation; Phenylurea Compounds; Protein Conformation; Receptors, Nicotinic | 2012 |
Luminal transport of thiol S-conjugates of methylmercury in isolated perfused rabbit renal proximal tubules.
Topics: Acetylcysteine; Animals; Biological Transport; Cysteine; Female; Glutathione; In Vitro Techniques; Isoxazoles; Kidney Tubules, Proximal; Methylmercury Compounds; Rabbits; Unithiol | 2012 |
Novel bioactivation mechanism of reactive metabolite formation from phenyl methyl-isoxazoles.
Topics: Carbamates; Carbon; Cysteine; Glutathione; Humans; Isoxazoles; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microsomes, Liver; NADP; NAV1.1 Voltage-Gated Sodium Channel; Nitrogen; Oxidation-Reduction; Urea; Voltage-Gated Sodium Channel Blockers | 2012 |
[Anti-rheumatic drugs].
Topics: Antirheumatic Agents; Cysteine; Hematologic Diseases; Humans; Hypersensitivity; Infections; Isoxazoles; Kidney Diseases; Leflunomide; Liver Neoplasms; Lung Diseases; Methotrexate | 2012 |
Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand.
Topics: Alanine; Amides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Bridged Bicyclo Compounds; Carboxylic Acids; Catalytic Domain; Crystallography, X-Ray; Cysteine; Humans; Isoxazoles; Molecular Structure; Protease Inhibitors | 2018 |