Page last updated: 2024-08-21

isoxazoles and afoxolaner

isoxazoles has been researched along with afoxolaner in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's49 (76.56)24.3611
2020's15 (23.44)2.80

Authors

AuthorsStudies
Chester, TS; Dumont, P; Fourie, JJ; Hunter, JS; Larsen, DL; Young, DR1
Blair, J; Chester, TS; Dumont, P; Fourie, JJ; Larsen, DL1
Daly, S; Drag, M; Dumont, P; Kunkle, B; Larsen, D1
Chester, TS; Drag, M; Kinoshita, G; Kondo, Y; Larsen, D1
Otranto, D1
Drag, M; Harriman, J; Larsen, D; Saik, J1
Benner, EA; Confalone, PN; Cordova, D; Dietrich, RF; Gould, BR; Hartline, EJ; Jones, GS; Kinney, JB; Lahm, GP; Long, JK; McDowell, RG; Rhoades, DF; Schroeder, ME; Shoop, WL; Waddell, ME; Wagerle, T; Xu, M1
Chester, TS; Dumont, P; Gale, B; Larsen, DL1
Drag, M; Harriman, J; Huang, R; Kvaternick, V; Letendre, L; Soll, M1
Larsen, D; McCall, JW; Mitchell, EB; Theodore Chester, S1
Chester, TS; Drag, MD; Kunkle, BN; Larsen, DL1
Beugnet, F; Erasmus, H; Fourie, J; Halos, L; Labuschagné, M; Larsen, D1
Beugnet, F; deVos, C; Fourie, J; Halos, L; Liebenberg, J1
Beugnet, F; Chalvet-Monfray, K; Halos, L; Larsen, D; Lebon, W1
Beugnet, F; Halos, L; Liebenberg, J2
Carithers, D; Chwala, M; Crevoiserat, L; Dryden, MW; Foley, KM; Hawkins, A; Jones, E; McGrady, JC; Patton, PR; Smith, V1
Emmerich, IU1
Davis, WL; Everett, WR; Hostetler, J; Ohmes, CM; Settje, T1
Rumschlag, AJ; Ryan, WG; Snyder, DE; Young, LM1
Anderson, A; de Vos, C; Fourie, JJ; Jeannin, P; Larsen, DL; Rehbein, S1
Becskei, C; Cuppens, O; Geurden, T; Liebenberg, J; Mahabir, SP; Six, RH1
Beugnet, F; de Vos, C; Halos, L; Larsen, D1
Crafford, D; Erasmus, H; Fourie, JJ; Jongejan, F; Schunack, B1
Beugnet, F; de Vos, C; Fourie, J; Halos, L; Larsen, D; Liebenberg, J1
Bennett, T; Canfield, MS; Crevoiserat, L; Dryden, MW; Foley, KM; Green, K; Heaney, K; Kalosy, K; Math, L; McGrady, JC; Royal, C; Smith, A; Smith, V; Sun, F; Tebaldi, C1
Bowman, DD; Crafford, D; Dorr, P; Fankhauser, R; Hamel, D; Larsen, DL; Reinemeyer, CR; Ulrich, M; Yoon, S1
Beugnet, F; Crafford, D; de Vos, C; Fourie, J; Kok, D; Larsen, D1
Beugnet, F; Dumont, P; Halos, L; Jeannin, P; Larsen, D; Lebon, W; Rehbein, S; Tielemans, E; Yoon, S1
Kumar, S; Padivitage, N; Rustum, A1
Breiltgens, T; Brianti, E; Capári, B; Dantas-Torres, F; Dollhofer, D; Gau, M; Jeannin, P; Joachim, A; Kaulfuß, KH; Kirkova, Z; Kley, K; Knaus, M; Lebon, W; Lechner, J; Mallouk, Y; Mihalca, AD; Mirabito, R; Petkevičius, S; Rapti, D; Rehbein, S; Sedeilhan, M; Shukullari, E; Visser, M1
Drag, M; Harriman, J; Larsen, D; Letendre, L; Saik, J; Yoon, S1
Kumar, S; Rustum, A; Zhuang, J1
Armstrong, R; Burgio, F; Meyer, L1
Carithers, D; Crawford, J; de Vos, C; Fourie, J; Lotriet, A1
Bruellke, N; Davis, K; Hodge, A; Maeder, S; Packianathan, R1
Dumont, P; Larsen, D; Lebon, W; Rehbein, S; Taweethavonsawat, P; Tielemans, E1
Altet, L; Ferrer, L; Lam, ATH; Zewe, CM1
Beugnet, F; Fourie, J; Halos, L; Larsen, D; Lebon, W; Liebenberg, J1
Cavalleri, D; Chappell, K; Coble, S; Drake, J; Karadzovska, D; Murphy, M; Nanchen, S; Wiseman, S1
Curdi, JL; Gil, AE; Gomez, SA; Hernandez, JAC; Hernandez, PO; Peris, PP; Picado, A; Velasquez, RVO1
Barbieri Bastos, IP; Botelho, CB; Campos, DR; Correia, TR; Fernandes, JI; Lopes, NL; Machado, MA; Scott, FB1
Abbate, JM; Arfuso, F; Beugnet, F; Brianti, E; Gaglio, G; Giannetto, S; Halos, L; Napoli, E1
Beccati, M; Beugnet, F; Bourdeau, P; Brement, T; Bruet, V; Cekiera, A; Crosaz, O; Darmon, C; Guillot, J; Halos, L; Larsen, D; Lebon, W; Mosca, M; Pin, D; Pomorska Handwerker, D; Popiel, J; Tielemans, E1
Armstrong, R; Lavan, R; Normile, D; Tunceli, K1
Beugnet, F; Hampel, V; Knaus, M; Rehbein, S; Schäfer, J1
Heredia Cardenas, R; Miranda Contreras, L; Osorio Marquez, R; Rangel Díaz, J; Romero Núñez, C; Yarto Jaramillo, E1
Aouiche, N; Beugnet, F; Lebon, W; Lekouch, N; Meyer, L; Perier, N1
Beugnet, F; Meesaimongkon, P; Srifawattana, N; Tangtrongsup, S; Thitaram, N; Tinkruejeen, G; Tiwananthagorn, S1
Inskeep, T; Kryda, K; Mahabir, SP; Rugg, J1
Álvarez Zavala, MLÁ; Cruz López, E; Galicia Franco, E; Heredia Cárdenas, R; Miranda Contreras, L; Rangel Díaz, J; Romero Núñez, C; Yarto Jaramillo, E1
Bautista Gómez, LG; Flores Ortega, A; Heredia Cárdenas, R; Martin Cordero, A; Romero Núñez, C; Sheinberg Waisburd, G; Yarto Jaramillo, E1
Bullock, R; Carney, E; Dodds, WJ; Fritsche, HA; Jeffrey, J; Kimball, JP; Morgan, J; Palmieri, V1
Bautista Gómez, LG; Fuantos Gámez, BA; Heredia Cardenas, R; Miranda Contreras, L; Romero Núñez, C; Sheinberg Waisburd, G; Yarto Jaramillo, E1
Aouiche, N; Beugnet, F; Lebon, W; Liebenberg, J; Rautenbach, C; van der Mescht, L1
Beugnet, F; Cutolo, AA; Menz, I; Perier, N; Silva, FO; Thyssen, P1
Beugnet, F; Iatta, R; Mendoza-Roldan, JA; Otranto, D; Panarese, R; Zatelli, A1
Akki, FE; Beugnet, F; Lebon, W; Madder, M; Meyer, L1
Adhikari, S; Padivitage, N; Rustum, AM1
Beugnet, F; Iatta, R; Lebon, W; Lia, RP; Otranto, D; Panarese, R1
Drag, M; Mitchell, E; Tielemans, E1
Dreyer, SM; Vaughan, JA1
Beugnet, F; Deak, G; Mihalca, AD; Panait, LC; Rabei, Ș1
Berny, P; Beugnet, F; Brianti, E; España, B; Marino, M; Mendoza-Roldan, JA; Napoli, E; Otranto, D; Perles, L; Spadola, F1

Trials

24 trial(s) available for isoxazoles and afoxolaner

ArticleYear
The ability of an oral formulation of afoxolaner to block the transmission of Babesia canis by Dermacentor reticulatus ticks to dogs.
    Parasites & vectors, 2014, Jun-23, Volume: 7

    Topics: Acaricides; Administration, Oral; Animals; Babesia; Dermacentor; Dog Diseases; Dogs; Female; Isoxazoles; Male; Naphthalenes; Tick Infestations

2014
Afoxolaner against fleas: immediate efficacy and resultant mortality after short exposure on dogs.
    Parasite (Paris, France), 2014, Volume: 21

    Topics: Animals; Ctenocephalides; Dog Diseases; Dogs; Excitatory Amino Acid Antagonists; Flea Infestations; GABA Antagonists; Insect Proteins; Insecticides; Isoxazoles; Naphthalenes; Time Factors; Treatment Outcome

2014
Comparative speed of efficacy against Ctenocephalides felis of two oral treatments for dogs containing either afoxolaner or fluralaner.
    Veterinary parasitology, 2015, Jan-30, Volume: 207, Issue:3-4

    Topics: Administration, Oral; Animals; Ctenocephalides; Dog Diseases; Dogs; Flea Infestations; Insecticides; Isoxazoles; Naphthalenes; Time Factors; Treatment Outcome

2015
Comparative efficacy of two oral treatments for dogs containing either afoxolaner or fluralaner against Rhipicephalus sanguineus sensu lato and Dermacentor reticulatus.
    Veterinary parasitology, 2015, Apr-15, Volume: 209, Issue:1-2

    Topics: Animals; Dermacentor; Dogs; Female; Insecticides; Isoxazoles; Male; Naphthalenes; Rhipicephalus sanguineus; Tick Infestations

2015
Comparative Efficacy of an Imidacloprid/Flumethrin Collar (Seresto®) and an Oral Afoxolaner Chewable (NexGard®) against Tick (Dermacentor variabilis and Amblyomma americanum) Infestations on Dogs: a Randomised Controlled Trial.
    Parasitology research, 2015, Volume: 114 Suppl 1

    Topics: Administration, Oral; Administration, Topical; Animals; Dog Diseases; Dogs; Imidazoles; Insecticides; Isoxazoles; Ixodidae; Naphthalenes; Neonicotinoids; Nitro Compounds; Pyrethrins; Tick Infestations

2015
Speed of flea knockdown of spinosad compared to afoxolaner, and of spinosad through 28 days post-treatment in controlled laboratory studies.
    Parasites & vectors, 2015, Nov-09, Volume: 8

    Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Flea Infestations; Insecticides; Isoxazoles; Macrolides; Naphthalenes; Siphonaptera; Time Factors; United States

2015
Efficacy of oral afoxolaner plus milbemycin oxime chewables against induced infestations with Dermacentor reticulatus in dogs.
    Parasitology research, 2016, Volume: 115, Issue:5

    Topics: Acaricides; Administration, Oral; Animals; Dermacentor; Dog Diseases; Dogs; Drug Combinations; Isoxazoles; Macrolides; Naphthalenes; Tick Infestations; Treatment Outcome

2016
Efficacy of oral afoxolaner for the treatment of canine generalised demodicosis.
    Parasite (Paris, France), 2016, Volume: 23

    Topics: Acaricides; Administration, Oral; Animals; Dog Diseases; Dogs; Female; Follow-Up Studies; Imidazoles; Isoxazoles; Macrolides; Male; Mite Infestations; Naphthalenes; Neonicotinoids; Nitro Compounds; Skin; Tablets; Time Factors

2016
Comparative efficacy of oral administrated afoxolaner (NexGard™) and fluralaner (Bravecto™) with topically applied permethrin/imidacloprid (Advantix(®)) against transmission of Ehrlichia canis by infected Rhipicephalus sanguineus ticks to dogs.
    Parasites & vectors, 2016, 06-17, Volume: 9, Issue:1

    Topics: Acaricides; Administration, Oral; Administration, Topical; Animals; Arachnid Vectors; Dog Diseases; Dogs; Drug Combinations; Drug Therapy, Combination; Ehrlichia canis; Ehrlichiosis; Imidazoles; Insecticides; Isoxazoles; Naphthalenes; Neonicotinoids; Nitro Compounds; Permethrin; Rhipicephalus sanguineus; Tick Infestations

2016
Efficacy of afoxolaner in a clinical field study in dogs naturally infested with Sarcoptes scabiei.
    Parasite (Paris, France), 2016, Volume: 23

    Topics: Acaricides; Animals; Dog Diseases; Dogs; Female; Isoxazoles; Male; Naphthalenes; Sarcoptes scabiei; Scabies; Skin

2016
Evaluation of the efficacy of monthly oral administration of afoxolaner plus milbemycin oxime (NexGard Spectra(®), Merial) in the prevention of adult Spirocerca lupi establishment in experimentally infected dogs.
    Veterinary parasitology, 2016, Aug-15, Volume: 226

    Topics: Administration, Oral; Analysis of Variance; Animals; Anthelmintics; Aorta, Thoracic; Autopsy; Body Weight; Dog Diseases; Dogs; Esophagoscopy; Esophagus; Feces; Female; Isoxazoles; Macrolides; Male; Naphthalenes; Parasite Egg Count; Spirurida Infections; Thelazioidea

2016
Monthly administrations of milbemycin oxime plus afoxolaner chewable tablets to prevent Angiostrongylus vasorum infection in dogs.
    Parasites & vectors, 2016, 09-02, Volume: 9, Issue:1

    Topics: Angiostrongylus; Animals; Anthelmintics; Dog Diseases; Dogs; Drug Administration Schedule; Drug Synergism; Female; Isoxazoles; Macrolides; Male; Naphthalenes; Strongylida Infections; Tablets

2016
Safety evaluation of orally administered afoxolaner and milbemycin oxime in eight-week-old dogs.
    Journal of veterinary pharmacology and therapeutics, 2017, Volume: 40, Issue:5

    Topics: Administration, Oral; Animals; Antiparasitic Agents; Dog Diseases; Dogs; Female; Isoxazoles; Macrolides; Male; Naphthalenes

2017
Assessment of the insecticidal activity of afoxolaner against Aedes aegypti in dogs treated with NexGard
    Parasite (Paris, France), 2017, Volume: 24

    Topics: Administration, Oral; Aedes; Analysis of Variance; Animals; Body Weight; Dog Diseases; Dogs; Ectoparasitic Infestations; Female; Insect Vectors; Insecticides; Isoxazoles; Male; Naphthalenes

2017
A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio™) in eliminating fleas in client-owned dogs in the USA.
    Parasites & vectors, 2017, Nov-01, Volume: 10, Issue:1

    Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Flea Infestations; Hospitals, Animal; Insecticides; Isoxazoles; Naphthalenes; Siphonaptera; Tablets; United States

2017
Phlebotomine mortality effect of systemic insecticides administered to dogs.
    Parasites & vectors, 2018, 04-05, Volume: 11, Issue:1

    Topics: Absorption, Physiological; Animals; Disease Vectors; Dog Diseases; Dogs; Drug Combinations; Female; Insecticides; Isoxazoles; Leishmania infantum; Leishmaniasis, Visceral; Macrolides; Male; Naphthalenes; Phlebotomus

2018
Six-month field efficacy and safety of the combined treatment of dogs with Frontline Tri-Act® and NexGard Spectra®.
    Parasites & vectors, 2018, Jul-16, Volume: 11, Issue:1

    Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Female; Insect Vectors; Insecticides; Isoxazoles; Macrolides; Male; Naphthalenes; Parasitic Diseases, Animal; Permethrin; Pyrazoles

2018
Treatment of canine sarcoptic mange with afoxolaner (NexGard
    Parasite (Paris, France), 2018, Volume: 25

    Topics: Acaricides; Animals; Dog Diseases; Dogs; Female; Germany; Isoxazoles; Macrolides; Male; Naphthalenes; Portugal; Random Allocation; Scabies; Tablets; Treatment Outcome

2018
Effect of oral afoxolaner on naturally occurring infestations of peacocks by the louse Goniodes pavonis.
    Veterinary dermatology, 2019, Volume: 30, Issue:2

    Topics: Administration, Oral; Animals; Bird Diseases; Galliformes; Isoxazoles; Mite Infestations; Naphthalenes; Phthiraptera; Random Allocation; Tablets

2019
Assessment of the insecticidal activity of oral afoxolaner against Phlebotomus perniciosus in dogs.
    Parasite (Paris, France), 2019, Volume: 26

    Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Drug Administration Schedule; Female; Insecticides; Isoxazoles; Male; Naphthalenes; Phlebotomus; Tick Infestations

2019
Comparative efficacy of afoxolaner and ivermectin in dogs naturally infested with Rhipicephalus sanguineus sensu lato: A clinical field study conducted in Thailand.
    Veterinary parasitology, regional studies and reports, 2019, Volume: 18

    Topics: Acaricides; Animals; Dog Diseases; Dogs; Female; Isoxazoles; Ivermectin; Male; Naphthalenes; Rhipicephalus sanguineus; Thailand; Tick Infestations

2019
Safety and efficacy of a novel oral chewable combination tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against natural flea infestations in client-owned dogs in the USA.
    Parasites & vectors, 2020, Mar-01, Volume: 13, Issue:1

    Topics: Acaricides; Administration, Oral; Animals; Azetidines; Dermatitis; Dog Diseases; Dogs; Drug Combinations; Female; Flea Infestations; Hospitals, Animal; Isoxazoles; Macrolides; Male; Naphthalenes; Parasite Load; Pyrantel; Siphonaptera; Spiro Compounds; Tablets; Treatment Outcome; United States

2020
Efficacy of a single administration of afoxolaner (NexGard®) or fipronil plus permethrin (Frontline® Tri-Act) against Hyalomma marginatum ticks in dogs.
    Veterinary parasitology, regional studies and reports, 2021, Volume: 25

    Topics: Animals; Dog Diseases; Dogs; Isoxazoles; Naphthalenes; Permethrin; Pyrazoles; Ticks

2021
Efficacy of afoxolaner (NexGard®) against natural infestations with Trichodectes canis in dogs under field conditions.
    Parasites & vectors, 2022, Sep-07, Volume: 15, Issue:1

    Topics: Animals; Canidae; Dog Diseases; Dogs; Ischnocera; Isoxazoles; Naphthalenes

2022

Other Studies

40 other study(ies) available for isoxazoles and afoxolaner

ArticleYear
Evaluation of the curative and preventive efficacy of a single oral administration of afoxolaner against cat flea Ctenocephalides felis infestations on dogs.
    Veterinary parasitology, 2014, Apr-02, Volume: 201, Issue:3-4

    Topics: Administration, Oral; Animals; Antiparasitic Agents; Ctenocephalides; Dog Diseases; Dogs; Female; Flea Infestations; Isoxazoles; Male; Naphthalenes; Parasite Egg Count; Random Allocation; Treatment Outcome

2014
Evaluation of the efficacy of afoxolaner against two European dog tick species: Dermacentor reticulatus and Ixodes ricinus.
    Veterinary parasitology, 2014, Apr-02, Volume: 201, Issue:3-4

    Topics: Acaricides; Animals; Dermacentor; Dog Diseases; Dogs; Female; Isoxazoles; Ixodes; Male; Naphthalenes; Parasite Load; Random Allocation; Tick Infestations; Treatment Outcome

2014
Assessment of the efficacy of orally administered afoxolaner against Rhipicephalus sanguineus sensu lato.
    Veterinary parasitology, 2014, Apr-02, Volume: 201, Issue:3-4

    Topics: Acaricides; Administration, Oral; Animals; Dog Diseases; Dogs; Female; Isoxazoles; Male; Naphthalenes; Random Allocation; Rhipicephalus sanguineus; Tick Infestations; Treatment Outcome

2014
Evaluation of the efficacy of afoxolaner against Haemaphysalis longicornis on dogs.
    Veterinary parasitology, 2014, Apr-02, Volume: 201, Issue:3-4

    Topics: Acaricides; Animals; Dog Diseases; Dogs; Female; Isoxazoles; Ixodidae; Male; Naphthalenes; Random Allocation; Tick Infestations; Treatment Outcome

2014
NEXGARD®. Afoxolaner, a new oral insecticide-acaricide to control fleas and ticks in dogs. Editorial.
    Veterinary parasitology, 2014, Apr-02, Volume: 201, Issue:3-4

    Topics: Acaricides; Animals; Dogs; Flea Infestations; Insecticides; Isoxazoles; Naphthalenes; Siphonaptera; Tick Infestations; Ticks

2014
Safety evaluation of orally administered afoxolaner in 8-week-old dogs.
    Veterinary parasitology, 2014, Apr-02, Volume: 201, Issue:3-4

    Topics: Administration, Oral; Animals; Antiparasitic Agents; Body Weight; Dogs; Female; Isoxazoles; Male; Naphthalenes; Random Allocation; Safety

2014
Discovery and mode of action of afoxolaner, a new isoxazoline parasiticide for dogs.
    Veterinary parasitology, 2014, Apr-02, Volume: 201, Issue:3-4

    Topics: Animals; Antiparasitic Agents; Chloride Channels; Cockroaches; Dog Diseases; Dogs; Drosophila melanogaster; Electrophysiological Phenomena; Female; Flea Infestations; Isoxazoles; Male; Naphthalenes; Oocytes; Protein Binding; Random Allocation; Siphonaptera; Tick Infestations; Ticks; Xenopus laevis

2014
Curative and preventive efficacy of orally administered afoxolaner against Ctenocephalides canis infestation in dogs.
    Veterinary parasitology, 2014, Apr-02, Volume: 201, Issue:3-4

    Topics: Administration, Oral; Animals; Ctenocephalides; Dog Diseases; Dogs; Female; Flea Infestations; Isoxazoles; Male; Naphthalenes; Parasite Egg Count; Parasite Load; Treatment Outcome

2014
The intravenous and oral pharmacokinetics of afoxolaner used as a monthly chewable antiparasitic for dogs.
    Veterinary parasitology, 2014, Apr-02, Volume: 201, Issue:3-4

    Topics: Administration, Intravenous; Administration, Oral; Animals; Antiparasitic Agents; Area Under Curve; Dog Diseases; Dogs; Female; Flea Infestations; Isoxazoles; Male; Naphthalenes; Protein Binding; Tick Infestations

2014
Efficacy of afoxolaner against Ixodes scapularis ticks in dogs.
    Veterinary parasitology, 2014, Apr-02, Volume: 201, Issue:3-4

    Topics: Acaricides; Animals; Dog Diseases; Dogs; Female; Isoxazoles; Ixodes; Male; Naphthalenes; Parasite Load; Random Allocation; Tick Infestations; Treatment Outcome

2014
Assessment of the onset of action of afoxolaner against existing adult flea (Ctenocephalides felis) infestations on dogs.
    Veterinary parasitology, 2014, Apr-02, Volume: 201, Issue:3-4

    Topics: Administration, Oral; Animals; Antiparasitic Agents; Ctenocephalides; Dog Diseases; Dogs; Female; Flea Infestations; Isoxazoles; Male; Naphthalenes; Random Allocation; Time

2014
Immediate efficacy and persistent speed of kill of a novel oral formulation of afoxolaner (NexGardTM) against induced infestations with Ixodes ricinus ticks.
    Parasites & vectors, 2014, Sep-26, Volume: 7

    Topics: Acaricides; Administration, Oral; Animals; Dog Diseases; Dogs; Female; Isoxazoles; Ixodes; Male; Naphthalenes; Random Allocation; Tick Infestations; Time Factors

2014
Evaluation of afoxolaner chewables to control flea populations in naturally infested dogs in private residences in Tampa FL, USA.
    Parasites & vectors, 2015, May-24, Volume: 8

    Topics: Administration, Oral; Animals; Animals, Domestic; Dog Diseases; Dogs; Drug Evaluation; Female; Flea Infestations; Insecticides; Isoxazoles; Male; Naphthalenes; Pest Control; Pets; Siphonaptera

2015
[New drugs for small animals in 2014].
    Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere, 2015, Volume: 43, Issue:3

    Topics: Animals; Cats; Dogs; Guanidines; Insulin; Isoxazoles; Ketoconazole; Naphthalenes; Neonicotinoids; Nitro Compounds; Pyrimidines; Sulfonamides; Veterinary Drugs

2015
Comparative speed of kill of oral treatments with Simparica™ (sarolaner) and Bravecto®(fluralaner) against induced infestations of Rhipicephalus sanguineus on dogs.
    Parasites & vectors, 2016, Feb-24, Volume: 9

    Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Insecticides; Isoxazoles; Ixodes; Naphthalenes; Placebos; Random Allocation; Survival Analysis; Tick Infestations; Time Factors; Treatment Outcome

2016
Evaluation of fluralaner and afoxolaner treatments to control flea populations, reduce pruritus and minimize dermatologic lesions in naturally infested dogs in private residences in west central Florida USA.
    Parasites & vectors, 2016, 06-28, Volume: 9, Issue:1

    Topics: Animals; Dog Diseases; Dogs; Flea Infestations; Florida; Insecticides; Isoxazoles; Naphthalenes; Pruritus; Siphonaptera

2016
Efficacy of oral afoxolaner plus milbemycin oxime chewables against induced gastrointestinal nematode infections in dogs.
    Veterinary parasitology, 2016, Jul-30, Volume: 225

    Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Drug Combinations; Isoxazoles; Macrolides; Naphthalenes; Nematode Infections; Random Allocation; Treatment Outcome

2016
Development and Validation of a Reversed-Phase Chiral HPLC Method to Determine the Chiral Purity of Bulk Batches of (
    Journal of AOAC International, 2017, Jan-01, Volume: 100, Issue:1

    Topics: Antiparasitic Agents; Chromatography, High Pressure Liquid; Isoxazoles; Naphthalenes; Stereoisomerism

2017
Efficacy against nematode infections and safety of afoxolaner plus milbemycin oxime chewable tablets in domestic dogs under field conditions in Europe.
    Parasitology research, 2017, Volume: 116, Issue:1

    Topics: Animals; Antinematodal Agents; Dog Diseases; Dogs; Europe; Feces; Isoxazoles; Macrolides; Naphthalenes; Nematoda; Nematode Infections; Praziquantel; Tablets; Treatment Outcome

2017
Development and Validation of a Normal Phase Chiral HPLC Method for Analysis of Afoxolaner Using a Chiralpak® AD-3 Column.
    Journal of chromatographic science, 2016, Volume: 54, Issue:10

    Topics: Amylose; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Isoxazoles; Naphthalenes; Phenylcarbamates; Reproducibility of Results; Stereoisomerism

2016
A comparative laboratory trial evaluating the immediate efficacy of fluralaner, afoxolaner, sarolaner and imidacloprid + permethrin against adult Rhipicephalus sanguineus (sensu lato) ticks attached to dogs.
    Parasites & vectors, 2016, 12-03, Volume: 9, Issue:1

    Topics: Acaricides; Administration, Oral; Animals; Dog Diseases; Dogs; Female; Imidazoles; Isoxazoles; Male; Naphthalenes; Neonicotinoids; Nitro Compounds; Parasite Load; Permethrin; Random Allocation; Rhipicephalus sanguineus; Tick Infestations; Treatment Outcome

2016
Assessment of afoxolaner efficacy against Otodectes cynotis infestations of dogs.
    Parasites & vectors, 2016, 12-09, Volume: 9, Issue:1

    Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Drug-Related Side Effects and Adverse Reactions; Insecticides; Isoxazoles; Mite Infestations; Naphthalenes; Otoscopy; Psoroptidae; Treatment Outcome

2016
Comparative speed of kill of sarolaner (Simparica
    Parasites & vectors, 2017, 02-21, Volume: 10, Issue:1

    Topics: Animals; Australia; Azetidines; Dog Diseases; Dogs; Isoxazoles; Ixodes; Naphthalenes; Parasite Load; Placebos; Random Allocation; Spiro Compounds; Survival Analysis; Tick Infestations; Time Factors

2017
Efficacy of afoxolaner plus milbemycin oxime chewable tablets (NexGard Spectra
    Veterinary parasitology, 2017, Apr-30, Volume: 238

    Topics: Ancylostoma; Ancylostomiasis; Animals; Anthelmintics; Dog Diseases; Dogs; Drug Combinations; Female; Isoxazoles; Macrolides; Male; Naphthalenes; Tablets

2017
Afoxolaner and fluralaner treatment do not impact on cutaneous Demodex populations of healthy dogs.
    Veterinary dermatology, 2017, Volume: 28, Issue:5

    Topics: Acaricides; Animals; Dog Diseases; Dogs; Female; Isoxazoles; Male; Mite Infestations; Mites; Naphthalenes; Treatment Outcome

2017
Efficacy of afoxolaner in the treatment of otodectic mange in naturally infested cats.
    Veterinary parasitology, 2018, May-30, Volume: 256

    Topics: Acaricides; Animals; Cat Diseases; Cats; Isoxazoles; Mite Infestations; Naphthalenes; Treatment Outcome

2018
Efficacy of two formulations of afoxolaner (NexGard® and NexGard Spectra®) for the treatment of generalised demodicosis in dogs, in veterinary dermatology referral centers in Europe.
    Parasites & vectors, 2018, Sep-10, Volume: 11, Issue:1

    Topics: Acaricides; Administration, Oral; Animals; Anthelmintics; Dog Diseases; Dogs; Drug Compounding; Female; Isoxazoles; Macrolides; Male; Mite Infestations; Mites; Naphthalenes; Skin; Treatment Outcome

2018
Dog owner flea/tick medication purchases in the USA.
    Parasites & vectors, 2018, Nov-06, Volume: 11, Issue:1

    Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Flea Infestations; Hospitals, Animal; Humans; Insecticides; Isoxazoles; Macrolides; Medication Adherence; Naphthalenes; Ownership; Prescription Drugs; Records; Siphonaptera; Ticks; United States; Veterinary Drugs; Veterinary Medicine

2018
Use of afoxolaner for the treatment of lice (Goniodes pavonis) in different genera (Chrysolophus spp, Lophura spp, Phasianus spp, and Syrmaticus spp) and species of pheasants and West Mexican Chachalacas (Ortalis poliocephala).
    Veterinary parasitology, 2020, Volume: 280

    Topics: Animals; Bird Diseases; Galliformes; Insect Control; Insecticides; Ischnocera; Isoxazoles; Lice Infestations; Naphthalenes

2020
Evaluation of the effect of afoxalaner with milbemycin 1 oxime in the treatment of rabbits naturally infected with Psoroptes cuniculi.
    PloS one, 2020, Volume: 15, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Isoxazoles; Macrolides; Mite Infestations; Naphthalenes; Psoroptidae; Rabbits

2020
Survey of canine use and safety of isoxazoline parasiticides.
    Veterinary medicine and science, 2020, Volume: 6, Issue:4

    Topics: Animals; Antiparasitic Agents; Azetidines; Dog Diseases; Dogs; Flea Infestations; Isoxazoles; Naphthalenes; Spiro Compounds; Tick Infestations

2020
Successful treatment of Ophionyssus natricis with afoxolaner in two Burmese pythons (Python molurus bivittatus).
    Veterinary dermatology, 2020, Volume: 31, Issue:6

    Topics: Animals; Boidae; Isoxazoles; Mite Infestations; Mites; Naphthalenes

2020
Insecticidal efficacy of afoxolaner against bedbugs, Cimex lectularius, when administered orally to dogs.
    Parasite (Paris, France), 2021, Volume: 28

    Topics: Administration, Oral; Animals; Bedbugs; Dogs; Insecticides; Isoxazoles; Naphthalenes

2021
Efficacy of afoxolaner (NexGard®) on the treatment of myiasis caused by the New World screwworm fly Cochliomyia hominivorax (Diptera: Calliphoridae) in naturally infested dogs.
    Veterinary parasitology, regional studies and reports, 2021, Volume: 24

    Topics: Animals; Calliphoridae; Diptera; Dog Diseases; Dogs; Isoxazoles; Myiasis; Naphthalenes

2021
Efficacy of afoxolaner (NexGard®) in preventing the transmission of Leishmania infantum and Dirofilaria immitis to sheltered dogs in a highly endemic area.
    Parasites & vectors, 2021, Jul-29, Volume: 14, Issue:1

    Topics: Animals; Dirofilaria immitis; Dirofilariasis; Dog Diseases; Dogs; Endemic Diseases; Female; Insect Vectors; Isoxazoles; Leishmania infantum; Leishmaniasis, Visceral; Mosquito Vectors; Naphthalenes; Psychodidae; Weather

2021
Assay of afoxolaner and determination of its related substances in commercial bulk batches of afoxolaner by reversed-phase HPLC method based on a short octadecyl column.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021, Nov-01, Volume: 1184

    Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Isoxazoles; Limit of Detection; Linear Models; Naphthalenes; Reproducibility of Results

2021
Efficacy of afoxolaner for the treatment of ear mite infestation under field conditions.
    Veterinary parasitology, 2021, Volume: 300

    Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Isoxazoles; Mite Infestations; Mites; Naphthalenes; Treatment Outcome

2021
Safety of oral afoxolaner formulated with or without milbemycin oxime in homozygous MDR1-deficient collie dogs.
    Journal of veterinary pharmacology and therapeutics, 2022, Volume: 45, Issue:4

    Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Isoxazoles; Macrolides; Naphthalenes

2022
Survival and Fecundity of Anopheles stephensi and Anopheles albimanus Mosquitoes (Diptera: Culicidae) After Ingesting Bovine Blood Containing Various Veterinary Systemic Parasiticides.
    Journal of medical entomology, 2022, 09-14, Volume: 59, Issue:5

    Topics: Animals; Anopheles; Antiparasitic Agents; Cattle; Cattle Diseases; Fertility; Insecticides; Isoxazoles; Ivermectin; Malaria; Mosquito Control; Mosquito Vectors; Naphthalenes

2022
Afoxolaner (NexGard®) in pet snakes for the treatment and control of Ophionyssus natricis (Mesostigmata: Macronyssidae).
    Parasites & vectors, 2023, Jan-06, Volume: 16, Issue:1

    Topics: Animals; Dog Diseases; Dogs; Isoxazoles; Mite Infestations; Mites; Snakes

2023