Compounds > isoxazoles
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isoxazoles and 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin

isoxazoles has been researched along with 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chatterjee, M; Djuzenova, CS; Flentje, M; Jensen, MR; Stingl, L; Stühmer, T1
Hartson, SD; Lacroix, JC; Matts, RL; Rogers, CN; Rogers, J; Voruganti, S1
Chrysikos, D; Dimopoulos, MA; Papadimitriou, CA; Psaltopoulou, T; Sergentanis, TN; Zagouri, F1
He, K; Yu, J; Zhang, L; Zheng, X1
Dong, DD; Huang, QS; Huyan, T; Li, Q; Shang, P; Yang, H; Yin, DC; Zhang, J1
Dempsey-Hibbert, NC; Lee, SL; Sutton, PA; Vimalachandran, D; Wardle, TD; Williams, JH1
Freissmuth, M; Nanoff, C; Puhm, F; Yang, Q1
Asfor, AS; Berryman, S; Curry, S; Jackson, T; Newman, J; Tuthill, TJ1
Caton, E; Meyer, KJ; Shapiro, TA1

Reviews

1 review(s) available for isoxazoles and 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin

ArticleYear
Hsp90 inhibitors in breast cancer: a systematic review.
    Breast (Edinburgh, Scotland), 2013, Volume: 22, Issue:5

    Topics: Adenine; Antineoplastic Agents; Benzamides; Benzoquinones; Biomarkers, Tumor; Female; Glycine; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Indazoles; Isoxazoles; Lactams, Macrocyclic; Pyridines; Resorcinols; Triazoles; Triple Negative Breast Neoplasms

2013

Other Studies

8 other study(ies) available for isoxazoles and 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin

ArticleYear
Novel HSP90 inhibitors, NVP-AUY922 and NVP-BEP800, radiosensitise tumour cells through cell-cycle impairment, increased DNA damage and repair protraction.
    British journal of cancer, 2010, May-25, Volume: 102, Issue:11

    Topics: Benzoquinones; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Down-Regulation; Drug Evaluation, Preclinical; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Lactams, Macrocyclic; Neoplasms; Pyrimidines; Radiation Tolerance; Radiation-Sensitizing Agents; Resorcinols; Up-Regulation

2010
The anticancer drug AUY922 generates a proteomics fingerprint that is highly conserved among structurally diverse Hsp90 inhibitors.
    Journal of proteome research, 2013, Aug-02, Volume: 12, Issue:8

    Topics: Antineoplastic Agents; Benzoquinones; Cell Survival; Chromatography, Liquid; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Jurkat Cells; Lactams, Macrocyclic; Macrolides; Protein Folding; Proteome; Resorcinols; Tandem Mass Spectrometry

2013
Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:11

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Benzoquinones; Cell Line, Tumor; Colorectal Neoplasms; DNA Damage; HCT116 Cells; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Lactams, Macrocyclic; Mice; Mice, Nude; Mitochondria; Proto-Oncogene Proteins; Resorcinols; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2013
Heat shock protein 90 inhibitors induce functional inhibition of human natural killer cells in a dose-dependent manner.
    Immunopharmacology and immunotoxicology, 2016, Volume: 38, Issue:2

    Topics: Adenine; Apoptosis; Benzoquinones; Cell Survival; Cytokines; Dose-Response Relationship, Drug; Down-Regulation; Female; Heterocyclic Compounds, 4 or More Rings; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Killer Cells, Natural; Lactams, Macrocyclic; Male; Pyridines; Resorcinols

2016
Re-examining HSPC1 inhibitors.
    Cell stress & chaperones, 2017, Volume: 22, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Caspase 3; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; HT29 Cells; Humans; Isoxazoles; Lactams, Macrocyclic; Molecular Chaperones; Pyridones; Pyrimidines; Resorcinols; RNA Interference; RNA, Small Interfering

2017
Hyponatremia and V2 vasopressin receptor upregulation: a result of HSP90 inhibition.
    Cancer chemotherapy and pharmacology, 2017, Volume: 80, Issue:4

    Topics: Benzoquinones; Cyclic AMP; Cytosol; HEK293 Cells; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; Hyponatremia; Isoxazoles; Lactams, Macrocyclic; Macrolides; Receptors, Vasopressin; Resorcinols; RNA Interference; Up-Regulation; Vasopressins

2017
The Cellular Chaperone Heat Shock Protein 90 Is Required for Foot-and-Mouth Disease Virus Capsid Precursor Processing and Assembly of Capsid Pentamers.
    Journal of virology, 2018, 03-01, Volume: 92, Issue:5

    Topics: 3C Viral Proteases; Animals; Benzoquinones; Capsid Proteins; Cell Line; Cell Survival; Cell-Free System; Cricetinae; Cysteine Endopeptidases; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; HSP90 Heat-Shock Proteins; Isoxazoles; Lactams, Macrocyclic; Molecular Chaperones; Protein Precursors; Protein Processing, Post-Translational; Resorcinols; RNA, Viral; Viral Proteins; Virus Assembly; Virus Replication

2018
Model System Identifies Kinetic Driver of Hsp90 Inhibitor Activity against African Trypanosomes and Plasmodium falciparum.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:8

    Topics: Animals; Antineoplastic Agents; Antiprotozoal Agents; Area Under Curve; Benzodioxoles; Benzoquinones; Biological Assay; Disease Models, Animal; Drug Repositioning; Female; Gene Expression; HSP90 Heat-Shock Proteins; Imidazoles; Isoxazoles; Lactams, Macrocyclic; Malaria, Falciparum; Mice; Models, Biological; Plasmodium falciparum; Protozoan Proteins; Resorcinols; Trypanosoma brucei brucei; Trypanosomiasis, African

2018