Page last updated: 2024-09-04

isovitexin and apigenin

isovitexin has been researched along with apigenin in 104 studies

Compound Research Comparison

Studies
(isovitexin)
Trials
(isovitexin)
Recent Studies (post-2010)
(isovitexin)
Studies
(apigenin)
Trials
(apigenin)
Recent Studies (post-2010) (apigenin)
1230813,273752,086

Protein Interaction Comparison

ProteinTaxonomyisovitexin (IC50)apigenin (IC50)
Chain A, Casein kinase II subunit alphaZea mays1.2
Chain A, Casein kinase II subunit alphaZea mays1.2
Chain A, Casein Kinase Ii Subunit AlphaZea mays1.2
Aldo-keto reductase family 1 member B10Homo sapiens (human)6.6
G2/mitotic-specific cyclin-B2Homo sapiens (human)4
Poly [ADP-ribose] polymerase tankyrase-1Homo sapiens (human)3.1311
Estrogen receptorHomo sapiens (human)1.253
Cytochrome P450 1A1Homo sapiens (human)0.427
MyeloperoxidaseHomo sapiens (human)3.8
Cytochrome P450 1A2Homo sapiens (human)0.795
Cyclin-dependent kinase 1Homo sapiens (human)4
Beta-glucuronidaseRattus norvegicus (Norway rat)2.8
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)6.67
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 23.02
Androgen receptorHomo sapiens (human)5.2
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.94
AromataseHomo sapiens (human)3.275
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)0.71
Pyruvate kinase PKMHomo sapiens (human)0.99
G2/mitotic-specific cyclin-B1Homo sapiens (human)4
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)2.175
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)2.175
Casein kinase II subunit alpha'Homo sapiens (human)0.85
Amine oxidase [flavin-containing] AHomo sapiens (human)1.398
Amine oxidase [flavin-containing] BHomo sapiens (human)1.12
Dipeptidyl peptidase 4Homo sapiens (human)0.14
Proteasome subunit beta type-5Homo sapiens (human)1.4
Prostaglandin G/H synthase 2Homo sapiens (human)8
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)1.45
Tyrosine-protein kinase SYKHomo sapiens (human)4.2
Xanthine dehydrogenase/oxidaseHomo sapiens (human)1.95
Glycogen synthase kinase-3 alphaHomo sapiens (human)1.4
Glycogen synthase kinase-3 betaHomo sapiens (human)1.4
Mitogen-activated protein kinase 10Homo sapiens (human)2.2
Casein kinase II subunit betaHomo sapiens (human)0.85
Casein kinase II subunit alphaHomo sapiens (human)0.84
Xanthine dehydrogenase/oxidaseBos taurus (cattle)3.57
MO15-related protein kinase Pfmrk Plasmodium falciparum (malaria parasite P. falciparum)7
Cyclin-dependent kinase 6Homo sapiens (human)2.08
Cyclin-dependent-like kinase 5 Homo sapiens (human)2.06
Cyclin homologHerpesvirus saimiri (strain 11)2.175
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)2.06
Mitogen-activated protein kinase 14Homo sapiens (human)2.2
Cytochrome P450 1B1Homo sapiens (human)0.1925
Integrase Human immunodeficiency virus 11.5
Casein kinase II subunit alpha 3Homo sapiens (human)0.8
G2/mitotic-specific cyclin-B3Homo sapiens (human)4
Estrogen receptor betaHomo sapiens (human)0.13
Aurora kinase BHomo sapiens (human)3.96
NACHT, LRR and PYD domains-containing protein 3 Homo sapiens (human)10
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)2.175
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)2.9256
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.308
NADPH oxidase 4Homo sapiens (human)1.13
Inositol hexakisphosphate kinase 2Homo sapiens (human)7.1
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)4.5

Research

Studies (104)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.96)18.7374
1990's1 (0.96)18.2507
2000's23 (22.12)29.6817
2010's59 (56.73)24.3611
2020's20 (19.23)2.80

Authors

AuthorsStudies
Amić, D; Lucić, B1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Chang, CC; Ho, SL; Lee, SS1
Steyns, JM; van Brederode, J1
Kitsos, CM; Stadtländer, CT1
Eggmann, T; Frangne, N; Klein, M; Koblischke, C; Martinoia, E; Weissenböck, G1
Chen, CT; Lee, HH; Lin, CM; Lin, JK1
Aquino, R; Barbato, F; Lauro, MR; Mencherini, T; Picerno, P1
Chumala, PB; Pedras, MS; Suchy, M1
Chai, Y; Fan, G; Hong, Z; Peng, J; Wu, Y1
Chen, CT; Chiang, BH; Chieng, KT; Huang, SH; Huang, ST; Kuo, HS; Lin, CM; Wang, LF1
De Simone, F; Mahmood, N; Mora, G; Piccinelli, AL; Poveda, L; Rastrelli, L1
Chang, YC; Chen, CT; Chen, TY; Huang, ST; Liang, YC; Lin, CM; Lin, MS; Shih, CM1
Fan, GR; Peng, JY; Wu, YT1
Chen, L; Fu, Y; Hou, C; Li, S; Liu, W; Shi, X; Tong, M; Zu, Y1
Conforti, P; Consolini, AE; Ragone, MI; Sella, M; Volonté, MG1
Du, SS; Lei, N; Li, L; Wang, YY; Zhang, WS; Zheng, YF1
Dong, Q; Huang, Y; Qiao, SY1
Chen, L; Efferth, T; Fu, Y; Hou, C; Kong, Y; Liu, W; Tong, M; Zhang, L; Zu, Y1
Jang, DS; Kim, JH; Kim, JM; Kim, JS; Kim, YS; Lee, YM; Yoo, JL1
Kaewkrud, W; Kanchanapoom, T; Otsuka, H; Ruchirawat, S1
Conforti, F; Loizzo, MR; Menichini, F; Rigano, D; Senatore, F1
Farag, SF; Mohamed, GA; Mohamed, MH; Omobuwajo, OR; Proksch, P; Sayed, HM1
Liu, GM; Xia, CL; Zhang, H1
Que, S; Shi, YP; Wu, XD; Yang, HP1
Lou, LH; Xue, YQ; Yin, MW; Yuan, K1
Dai, Z; Fang, ZJ; Li, SY1
Chen, ST; Chen, TY; Lee, MH; Lin, YP; Tseng, HW1
Lehmann, RP; Pearson, T; Penman, KG; Wohlmuth, H1
Cazarolli, LH; Folador, P; Gazola, AC; Reginatto, FH; Schenkel, EP; Silva, FR1
Chen, YJ; Du, XF; Ling, TJ; Ling, WW; Wan, XC; Xia, T; Zhang, ZZ1
Hua, Z; Tang, WX; Wang, JL; Zhang, SJ; Zhao, BY1
Cheng, X; Ren, G; Wang, L; Wang, S; Yao, Y1
Kano, Y; Wu, CF; Xu, ZL; Yang, JY; Yuan, D; Zhang, L1
Gao, Q; Ni, Q; Wang, S; Wang, Z; Xu, G; Zhang, Y1
Li, LX; Ling, TJ; Luo, ZM; Wan, XC; Zhang, YJ; Zhang, ZZ; Zhu, HT1
Choo, CY; Man, F; Sulong, NY; Wong, TW1
Lin, L; Liu, H; Yan, C1
Blaut, M; Braune, A1
Cao, D; Cao, J; Jiang, W; Li, H; Yi, J1
Li, Z; Lu, H; Lu, Y; Ma, X; Yan, R; Yu, S1
Arruda, LL; Bannwart, G; Bersani-Amado, CA; Botelho, MF; Fabrão, RM; Ignoato, MC; Pomini, AM; Santin, SM; Schuquel, IT1
Dixit, M; Joksić, G; Kesavan, R; Nastasijević, B; Potunuru, UR; T, A1
Ahamed, MB; Asmawi, MZ; Farsi, E; Hor, SY; Ismail, Z; Shafaei, A; Yam, MF1
Castellanos, LH; Costa, GM; da Rocha, RF; da Silva Morrone, M; de Assis, AM; Gasparotto, J; Gazola, AC; Gelain, DP; Moreira, JC; Ramos, FA; Reginatto, FH; Schenkel, EP; Zucolotto, SM1
Diallo, D; Malterud, KE; Nguyen, C; Pham, AT; Wangensteen, H1
Jiang, Y; Li, YR; Tu, PF; Zou, PP1
Caruso, ÍP; Cornélio, ML; de Souza, FP; Fossey, MA; Vilegas, W1
He, H; Lu, YH; Yang, JP1
Li, SH; She, CW; Wu, XJ1
Baissac, Y; Bidel, LPR; Chomicki, G; Coiro, M; Jay-Allemand, C; Ming, F; Renner, SS; Wang, Y; Zhang, X1
Chelyn, JL; Ismail, Z; Mohd Yousof, NS; Omar, MH; Ranggasamy, R; Wasiman, MI1
Cheng, M; Meng, LJ; Yu, SF; Zhou, GX; Zhou, XD; Zou, HL1
Chen, C; Guo, XF; Meng, ZF; Tang, F; Yu, J; Yue, YD; Zhang, CJ1
Choi, M; Choi, S; Ha, TJ; Kang, I; Lee, BW; Lee, M; Wi, HR1
Gao, Y; Huang, X; Xu, Z; Yang, T; Zhang, G; Zou, Y1
Guo, J; Li, H; Li, Y; Xie, J; Yang, T; Zhang, Y; Zhao, Q1
Granica, S; Horn, G; Kiss, AK; Kluge, H; Matkowski, A1
Lu, Y; Ma, X; Ou, S; Wang, E; Wang, Y; Yan, R1
França, Sde C; Guimarães, CC; Oliveira, DD; Pereira, AM; Pereira, PS; Pereira, SI; Saltoratto, AL; Valdevite, M1
Cheng, G; Ci, X; Lv, H; Qin, X; Wang, L; Yu, Z; Zheng, Y1
Ji, XY; Li, QR; Wei, Q; Xu, F; Yin, H1
Borges, TV; Dos Santos, KC; Ludka, FK; Molz, S; Olescowicz, G; Santos, CA1
Bendre, R; Bera, AK; Chandel, S; Dixit, M; Ganugula, R; Giri, H; Joksic, G; Kesavan, R; Kumar, PU; Potunuru, UR; Reddy, GB; Sahu, G; Upadhyay, S1
Cigić, B; Hribar, J; Polak, T; Požrl, T; Terpinc, P1
Dočekal, B; Oravec, M; Pompeiano, A; Tříska, J; Urban, O; Večeřa, Z; Večeřová, K1
Costa, AM; da Cunha, MSB; de Carvalho, MVO; Gadioli, IL; Pineli, LLO1
He, M; He, XH; Kong, WL; Li, JX; Min, JW; Peng, BW1
Bhatt, V; Kumar, N; Sharma, S; Sharma, U; Singh, B1
Cao, Q; Li, W; Liu, S; Ma, C; Sun, J; Sun, Y; Wang, Y; Xia, Y; Yang, K1
Ganesan, K; Xu, B1
Lv, SX; Qiao, X1
Abu Bakar, AR; Merican, AF; Mohamad, SB; Ripen, AM1
Brauch, D; Mock, HP; Pillen, K; Porzel, A; Schumann, E1
Kuang, Y; Ma, HX; Rao, BL; Ren, JN; Sha, MM; Xu, ZX1
Hu, JJ; Lin, MX; Pan, CW; Wang, H1
Eichenberger, M; Fischer, D; Larsen, AB; Mortensen, UH; Naesby, M; Vanegas, KG1
Liu, DH; Xu, YL; Zhang, ZL; Zuo, YM1
Bento, CC; de Almeida, LFR; Franco, DM; Hiruma-Lima, CA; Sannomiya, M; Sartori, ÂLB; Tangerina, MMP; Vilegas, W; Zanatta, AC1
de Souza, LM; Gasparotto Junior, A; Gasparotto, FM; Guarnier, LP; Lourenço, ELB; Marques, MA; Palozi, RAC; Schaedler, MI; Silva, AO; Tirloni, CAS1
McCullagh, M; Pereira, CAM; Yariwake, JH1
Geng, D; Liu, S; Wang, Q; Wang, R; Zheng, S1
Cao, J; Cao, X; Chen, A; Chen, X; Cui, Y; Li, X; Liu, L; Qiu, Y; Quan, M; Ren, K; Xu, C; Yuan, Q; Zhang, J; Zou, C1
Hatano, M; Mashima, K; Shimosaka, M; Suzuki, H; Taguchi, G1
Du, J; Fu, S; He, D; Hu, G; Huang, B; Li, Y; Liu, B; Liu, D; Ran, X1
Chen, L; Cheng, X; Tang, X; Yang, Q1
Liu, S; Wang, J; Zhang, X1
Guo, W; Liu, R; Liu, Y; Ma, H; Meng, C; Wang, C; Wang, W; Xie, S1
Chen, T; Deng, Y; Ehsanur Rahman, SM; Piao, M; Zhang, L1
Cao, J; Cao, X; Li, X; Liu, L; Ning, Y; Qiu, Y; Ren, K; Xu, C; Zhou, L1
Ding, M; Georgiev, MI; Huda, MN; Jahan, T; Jha, R; Lu, S; Park, SU; Zhang, K; Zhang, W; Zhou, M1
Chen, RL; He, JQ; Huang, P; Sun, CH; Wang, Z; Yu, CH; Yu, WY; Zhang, HH1
da Rocha, CQ; da Silva, MA; de Araújo Paula, FB; Duarte, SMDS; Figueiredo, SA; Leme, KC; Rodrigues, MR; Salles, BCC; Tangerina, MMP; Vilegas, W1
Abdulai, IL; Adinortey, MB; Boison, D; Gbewonyo, WS; Kwofie, SK; Puplampu, JB1
Abdul Hamid, H; Mehat, MZ; Stanslas, J; Zolkiffly, SZI1
Cao, J; Cao, X; Liu, F; Xia, L; Yuan, Q; Zhang, J1
Jiang, M; Zhao, N; Zhu, H1
Li, J; Ma, H; Wang, D; Wang, L; Wang, T; Xiang, H; Xue, J; Yang, P1
Li, P; Liu, W; Qu, X; Sun, X1
Chattopadhyay, N; Das, N; Maurya, R; Pal, S; Porwal, K; Rajak, S; Rajput, S; Sanyal, S; Siddiqi, MI; Singh, M; Sinha, RA; Trivedi, AK1
Li, Z; Zhang, B; Zhang, D; Zhou, Y1
Huang, Y; Li, R; Pan, S; Tao, M; Wu, T; Xu, T; Xu, X; Zhang, Z; Zogona, D1
Chattopadhyay, N; Chattopadhyay, S; Gayen, JR; Kulkarni, C; Pal, S; Porwal, K; Riyazuddin, M; Sanyal, S; Sharma, S1
Chen, Q; Guo, Y; Sun, L; Wu, B1

Reviews

4 review(s) available for isovitexin and apigenin

ArticleYear
A systematic review on phenolic compounds in Passiflora plants: Exploring biodiversity for food, nutrition, and popular medicine.
    Critical reviews in food science and nutrition, 2018, Mar-24, Volume: 58, Issue:5

    Topics: Apigenin; Flavonoids; Food Analysis; Glucosides; Luteolin; Passiflora; Phenols; Phytochemicals; Plant Extracts

2018
A review on the pharmacological effects of vitexin and isovitexin.
    Fitoterapia, 2016, Volume: 115

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apigenin; Drugs, Chinese Herbal; Humans; Molecular Structure; Neuroprotective Agents; Plants, Medicinal

2016
Molecular targets of vitexin and isovitexin in cancer therapy: a critical review.
    Annals of the New York Academy of Sciences, 2017, Volume: 1401, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apigenin; Cell Survival; Humans; Neoplasms; Plant Extracts

2017
Multitargeted Effects of Vitexin and Isovitexin on Diabetes Mellitus and Its Complications.
    TheScientificWorldJournal, 2021, Volume: 2021

    Topics: Animals; Apigenin; Diabetes Complications; Diabetes Mellitus; Humans; Hypoglycemic Agents

2021

Other Studies

100 other study(ies) available for isovitexin and apigenin

ArticleYear
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Acylated glucosylflavones as α-glucosidase inhibitors from Tinospora crispa leaf.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: alpha-Glucosidases; Ethanol; Flavonoids; Glucosides; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Molecular Docking Simulation; Molecular Structure; Plant Extracts; Plant Leaves; Solvents; Structure-Activity Relationship; Tinospora

2015
Variation in the substrate specificity of allozymes catalyzing flavone-O-glucoside biosynthesis in Silene plants.
    Biochemical genetics, 1986, Volume: 24, Issue:5-6

    Topics: Apigenin; Flavonoids; Genes; Genetic Variation; Geography; Glucosyltransferases; Hexosyltransferases; Pentosyltransferases; Plants; Substrate Specificity

1986
Helicobacter pylori in liquid culture: evaluation of growth rates and ultrastructure.
    Current microbiology, 1998, Volume: 37, Issue:2

    Topics: Agar; Apigenin; Cell Division; Culture Media; Flavonoids; Helicobacter pylori; Hemin; Microscopy, Electron; Preservation, Biological; Time Factors

1998
Flavone glucoside uptake into barley mesophyll and Arabidopsis cell culture vacuoles. Energization occurs by H(+)-antiport and ATP-binding cassette-type mechanisms.
    Plant physiology, 2002, Volume: 128, Issue:2

    Topics: Apigenin; Arabidopsis; ATP-Binding Cassette Transporters; Biological Transport, Active; Cells, Cultured; Flavonoids; Glucosides; Hordeum; Ion Transport; Kinetics; Luteolin; Plant Leaves; Tritium; Vacuoles

2002
Prevention of cellular ROS damage by isovitexin and related flavonoids.
    Planta medica, 2002, Volume: 68, Issue:4

    Topics: Apigenin; Cadmium; DNA Damage; Flavonoids; HL-60 Cells; Humans; Hydrogen Peroxide; Oryza; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; Xanthine; Xanthine Oxidase

2002
Phenolic constituents and antioxidant properties of Xanthosoma violaceum leaves.
    Journal of agricultural and food chemistry, 2003, Oct-22, Volume: 51, Issue:22

    Topics: Antioxidants; Apigenin; Biphenyl Compounds; Flavonoids; Free Radical Scavengers; Glycosides; Monosaccharides; Peroxides; Phenols; Picrates; Plant Extracts; Plant Leaves; Xanthosoma

2003
Phytoalexins from Thlaspi arvense, a wild crucifer resistant to virulent Leptosphaeria maculans: structures, syntheses and antifungal activity.
    Phytochemistry, 2003, Volume: 64, Issue:5

    Topics: Antifungal Agents; Apigenin; Copper; Flavonoids; Fungi; Phytoalexins; Plant Diseases; Plant Extracts; Plant Leaves; Sesquiterpenes; Terpenes; Thlaspi

2003
Preparative separation of isovitexin and isoorientin from Patrinia villosa Juss by high-speed counter-current chromatography.
    Journal of chromatography. A, 2005, May-13, Volume: 1074, Issue:1-2

    Topics: Apigenin; Countercurrent Distribution; Luteolin; Patrinia

2005
Inhibitory effects of a rice hull constituent on tumor necrosis factor alpha, prostaglandin E2, and cyclooxygenase-2 production in lipopolysaccharide-activated mouse macrophages.
    Annals of the New York Academy of Sciences, 2005, Volume: 1042

    Topics: Animals; Antioxidants; Apigenin; Cell Line; Cyclooxygenase 2; Dinoprostone; Lipopolysaccharides; Macrophages; Mice; Oryza; Tumor Necrosis Factor-alpha

2005
Anti-HIV activity of dibenzylbutyrolactone-type lignans from Phenax species endemic in Costa Rica.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:9

    Topics: 4-Butyrolactone; Anti-HIV Agents; Apigenin; Chemistry, Pharmaceutical; Costa Rica; Ethanol; Geography; Lactones; Lignans; Plant Extracts; Plant Leaves; Structure-Activity Relationship; Technology, Pharmaceutical; Urticaceae

2005
Isovitexin suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages.
    Planta medica, 2005, Volume: 71, Issue:8

    Topics: Animals; Antioxidants; Apigenin; DNA Primers; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oryza; Phytotherapy; Reverse Transcriptase Polymerase Chain Reaction

2005
[Studies on chemical constituents of Patrinia villosa].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:2

    Topics: Apigenin; Luteolin; Patrinia; Plants, Medicinal; Quercetin

2006
Preparative separation of vitexin and isovitexin from pigeonpea extracts with macroporous resins.
    Journal of chromatography. A, 2007, Jan-19, Volume: 1139, Issue:2

    Topics: Adsorption; Apigenin; Cajanus; Plant Extracts; Resins, Synthetic

2007
The spasmolytic effect of Aloysia citriodora, Palau (South American cedrón) is partially due to its vitexin but not isovitexin on rat duodenums.
    Journal of ethnopharmacology, 2007, Sep-05, Volume: 113, Issue:2

    Topics: Acetylcholine; Animals; Apigenin; Calcium Chloride; Dose-Response Relationship, Drug; Duodenum; Enzyme Inhibitors; Female; In Vitro Techniques; Isotonic Solutions; Lippia; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth; Papaverine; Parasympatholytics; Plant Extracts; Quercetin; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetraethylammonium; Water

2007
[Chemical constituents from a Tibetan medicine Arenaria kansuensis I].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:10

    Topics: Apigenin; Arenaria Plant; Flavones; Flavonoids; Glucosides; Plants, Medicinal; Tibet

2007
[Studies on chemical constituents from stellaria media. I].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:11

    Topics: Apigenin; Chromatography, High Pressure Liquid; Flavones; Galactosides; Plants, Medicinal; Stellaria

2007
Determination of vitexin and isovitexin in pigeonpea using ultrasonic extraction followed by LC-MS.
    Journal of separation science, 2008, Volume: 31, Issue:2

    Topics: Apigenin; Cajanus; Chromatography, High Pressure Liquid; Mass Spectrometry; Reference Standards; Temperature; Ultrasonics

2008
Aldose-reductase- and protein-glycation-inhibitory principles from the whole plant of Duchesnea chrysantha.
    Chemistry & biodiversity, 2008, Volume: 5, Issue:2

    Topics: Aldehyde Reductase; Animals; Apigenin; Ellagic Acid; Glycation End Products, Advanced; Glycosides; Lens, Crystalline; Molecular Structure; Oleanolic Acid; Quercetin; Rats; Rats, Sprague-Dawley; Rosaceae; Stereoisomerism; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2008
Megastigmane and flavone glycosides from Strophioblachia fimbricalyx Boerl.
    Journal of natural medicines, 2008, Volume: 62, Issue:1

    Topics: Apigenin; Cyclohexanones; Euphorbiaceae; Flavones; Flavonoids; Glucosides; Glycosides; Molecular Structure; Norisoprenoids; Plant Components, Aerial; Spectrum Analysis; Terpenes

2008
Protection against neurodegenerative diseases of Iris pseudopumila extracts and their constituents.
    Fitoterapia, 2009, Volume: 80, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Apigenin; Cell Line; Cholinesterase Inhibitors; Cytotoxins; Flavonoids; Glucosides; Inhibitory Concentration 50; Iris Plant; Isoflavones; Luteolin; Macrophages; Mice; Nitric Oxide; Plant Components, Aerial; Plant Extracts; Rhizome

2009
Fructose-amino acid conjugate and other constituents from Cyperus rotundus L.
    Natural product research, 2008, Volume: 22, Issue:17

    Topics: alpha-Amylases; Amino Acids; Antioxidants; Apigenin; Cyperus; Flavonoids; Fructose; Glucosides; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Stereoisomerism

2008
[Chemical constituents from herbs of Swertia delavayi].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:16

    Topics: Apigenin; Glucosides; Iridoid Glucosides; Iridoids; Luteolin; Magnetic Resonance Spectroscopy; Oleanolic Acid; Pyrones; Sitosterols; Spectrometry, Mass, Electrospray Ionization; Swertia

2008
[Studies on glycosides from Gentiana veitchiorum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:21

    Topics: Apigenin; Chromatography, High Pressure Liquid; Gentiana; Glucosides; Glycosides; Iridoid Glucosides; Iridoids

2008
[Simultaneous determination of four glycosylflavones from Lophatherum gracile by RP-HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:19

    Topics: Apigenin; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Glucosides; Glycosides; Poaceae; Reproducibility of Results

2008
[Studies on HPLC fingerprint chromatogram of Folium Fici Microcarpa].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:10

    Topics: Apigenin; Chromatography, High Pressure Liquid; Drug Contamination; Drugs, Chinese Herbal; Ficus; Plant Leaves; Plants, Medicinal; Quality Control; Reproducibility of Results

2008
Neural cell protective compounds isolated from Phoenix hanceana var. formosana.
    Phytochemistry, 2009, Volume: 70, Issue:9

    Topics: Animals; Apigenin; Apoptosis; Catechin; Glucosides; Luteolin; Magnoliopsida; Molecular Structure; Neuroprotective Agents; Oxidopamine; PC12 Cells; Plants, Medicinal; Quercetin; Rats; Stereoisomerism; Taiwan

2009
Pharmacognosy and chemotypes of passionflower (Passiflora incarnata L.).
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:6

    Topics: Anti-Anxiety Agents; Apigenin; Australia; Chromatography, High Pressure Liquid; Flavones; Glycosides; Hypnotics and Sedatives; Passiflora; Pharmacognosy; Phytotherapy; Plant Extracts

2010
Potential insulin secretagogue effects of isovitexin and swertisin isolated from Wilbrandia ebracteata roots in non-diabetic rats.
    Fitoterapia, 2010, Volume: 81, Issue:8

    Topics: Animals; Apigenin; Blood Glucose; Cucurbitaceae; Glipizide; Glucose Tolerance Test; Insulin; Insulin Secretion; Male; Molecular Structure; Rats; Rats, Wistar

2010
Antiseptic activity and phenolic constituents of the aerial parts of Vitex negundo var. cannabifolia.
    Molecules (Basel, Switzerland), 2010, Nov-18, Volume: 15, Issue:11

    Topics: Anti-Bacterial Agents; Apigenin; Bacillus subtilis; Escherichia coli; Flavonoids; gamma-Tocopherol; Micrococcus; Phenols; Plant Components, Aerial; Plant Extracts; Pseudomonas fluorescens; Sitosterols; Vitamin E; Vitex

2010
[Studies on the chemical constituents of Pharbitis purpurea].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:10

    Topics: Apigenin; Butanols; Convolvulaceae; Cyclohexanones; Glycosides; Molecular Structure; Plants, Medicinal; Sitosterols; Triterpenes; Ursolic Acid

2010
A determination of potential α-glucosidase inhibitors from Azuki Beans (Vigna angularis).
    International journal of molecular sciences, 2011, Volume: 12, Issue:10

    Topics: Apigenin; Ethanol; Fabaceae; Glucosidases; Glycoside Hydrolase Inhibitors; Plant Extracts; Protein Binding; Spectrometry, Fluorescence

2011
Two new flavonoid glycosides from Semen Ziziphi Spinosae.
    Journal of Asian natural products research, 2012, Volume: 14, Issue:2

    Topics: Apigenin; Drugs, Chinese Herbal; Flavonoids; Glycosides; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular

2012
Seasonal variations of the antioxidant composition in ground bamboo Sasa argenteastriatus leaves.
    International journal of molecular sciences, 2012, Volume: 13, Issue:2

    Topics: Antioxidants; Apigenin; Caffeic Acids; Chromatography, High Pressure Liquid; Coumaric Acids; Flavonoids; Glucosides; Phenols; Plant Extracts; Plant Leaves; Propionates; Sasa; Seasons; Triterpenes

2012
A new norisoprenoid and other compounds from Fuzhuan brick tea.
    Molecules (Basel, Switzerland), 2012, Mar-19, Volume: 17, Issue:3

    Topics: alpha-Linolenic Acid; Anti-Bacterial Agents; Apigenin; Camellia sinensis; Catechin; Enteropathogenic Escherichia coli; Gallic Acid; Molecular Structure; Norisoprenoids

2012
Vitexin and isovitexin from the Leaves of Ficus deltoidea with in-vivo α-glucosidase inhibition.
    Journal of ethnopharmacology, 2012, Aug-01, Volume: 142, Issue:3

    Topics: Animals; Apigenin; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Ficus; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Male; Mice; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley

2012
Simultaneous determination of vitexin and isovitexin in rat plasma after oral administration of Santalum album L. leaves extract by liquid chromatography tandem mass spectrometry.
    Biomedical chromatography : BMC, 2013, Volume: 27, Issue:2

    Topics: Administration, Oral; Animals; Apigenin; Chromatography, Liquid; Drug Stability; Male; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Reproducibility of Results; Santalum; Sensitivity and Specificity; Tandem Mass Spectrometry

2013
Intestinal bacterium Eubacterium cellulosolvens deglycosylates flavonoid C- and O-glucosides.
    Applied and environmental microbiology, 2012, Volume: 78, Issue:22

    Topics: Apigenin; Eubacterium; Hydrolysis; Luteolin; Molecular Structure

2012
Identification of the flavonoids in mungbean (Phaseolus radiatus L.) soup and their antioxidant activities.
    Food chemistry, 2012, Dec-15, Volume: 135, Issue:4

    Topics: Antioxidants; Apigenin; Flavonoids; Phaseolus; Plant Preparations

2012
Enzymatic acylation of isoorientin and isovitexin from bamboo-leaf extracts with fatty acids and antiradical activity of the acylated derivatives.
    Journal of agricultural and food chemistry, 2012, Oct-31, Volume: 60, Issue:43

    Topics: Acylation; Apigenin; Bambusa; Biocatalysis; Fatty Acids; Free Radical Scavengers; Fungal Proteins; Lipase; Luteolin; Molecular Structure; Plant Extracts; Plant Leaves

2012
Chemical constituents of Machaerium hirtum Vell. (Fabaceae) leaves and branches and its anti-inflammatory activity evaluation.
    Natural product research, 2013, Volume: 27, Issue:17

    Topics: Animals; Anti-Inflammatory Agents; Apigenin; Edema; Fabaceae; Magnetic Resonance Spectroscopy; Mice; Pentacyclic Triterpenes; Plant Extracts; Plant Leaves; Proline; Sitosterols; Stigmasterol; Triterpenes

2013
Inhibition of vascular smooth muscle cell proliferation by Gentiana lutea root extracts.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Animals; Apigenin; Becaplermin; Cell Cycle; Cell Proliferation; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Gentiana; Male; MAP Kinase Kinase 1; Muscle, Smooth, Vascular; Plant Extracts; Plant Roots; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Signal Transduction

2013
Genotoxicity and acute and subchronic toxicity studies of a standardized methanolic extract of Ficus deltoidea leaves.
    Clinics (Sao Paulo, Brazil), 2013, Volume: 68, Issue:6

    Topics: Animals; Apigenin; Body Weight; Chromatography, Liquid; Female; Ficus; Male; Methanol; Organ Size; Phytotherapy; Plant Extracts; Plant Leaves; Random Allocation; Rats; Rats, Sprague-Dawley; Toxicity Tests, Acute; Toxicity Tests, Subchronic

2013
Passiflora manicata (Juss.) aqueous leaf extract protects against reactive oxygen species and protein glycation in vitro and ex vivo models.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 60

    Topics: Animals; Antioxidants; Apigenin; Glutathione Peroxidase; Hydrogen Peroxide; Lipid Peroxidation; Liver; Luteolin; Male; Oxidative Stress; Passiflora; Plant Extracts; Plant Leaves; Protein Carbonylation; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2013
Bioactive flavone-C-glycosides of the African medicinal plant Biophytum umbraculum.
    Molecules (Basel, Switzerland), 2013, Aug-26, Volume: 18, Issue:9

    Topics: Apigenin; Arachidonate 15-Lipoxygenase; Flavones; Free Radical Scavengers; Glycosides; Lipoxygenase Inhibitors; Luteolin; Magnoliopsida; Plant Extracts; Plants, Medicinal; Xanthine Oxidase

2013
[Quality standard study on Vigna radiata].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:1

    Topics: Apigenin; Fabaceae; Quality Control

2014
Binding of antioxidant flavone isovitexin to human serum albumin investigated by experimental and computational assays.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 98

    Topics: Antioxidants; Apigenin; Binding Sites; Circular Dichroism; Flavonoids; Fluorescence; Humans; Protein Binding; Serum Albumin; Spectroscopy, Fourier Transform Infrared; Thermodynamics

2014
Four flavonoid compounds from Phyllostachys edulis leaf extract retard the digestion of starch and its working mechanisms.
    Journal of agricultural and food chemistry, 2014, Aug-06, Volume: 62, Issue:31

    Topics: alpha-Amylases; Apigenin; Bambusa; Digestion; Enzyme Inhibitors; Flavonoids; Food Additives; Glucosides; Luteolin; Molecular Docking Simulation; Plant Extracts; Plant Leaves; Starch

2014
[Chemical constituents of Indocalamus latifolius leaves].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:4

    Topics: Apigenin; Chlorogenic Acid; Molecular Structure; Plant Extracts; Plant Leaves; Sasa

2014
The velamen protects photosynthetic orchid roots against UV-B damage, and a large dated phylogeny implies multiple gains and losses of this function during the Cenozoic.
    The New phytologist, 2015, Volume: 205, Issue:3

    Topics: Acyltransferases; Apigenin; Crosses, Genetic; Flavonoids; Gene Duplication; Gene Expression Regulation, Plant; Glucosides; Orchidaceae; Photosynthesis; Phylogeny; Plant Roots; Stress, Physiological; Time Factors; Ultraviolet Rays

2015
Analysis of flavone C-glycosides in the leaves of Clinacanthus nutans (Burm. f.) Lindau by HPTLC and HPLC-UV/DAD.
    TheScientificWorldJournal, 2014, Volume: 2014

    Topics: Acanthaceae; Apigenin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Flavonoids; Glucosides; Glycosides; Luteolin; Malaysia; Plant Extracts; Plant Leaves

2014
[Chemical constituents of flavonoids and their glycosides in Melastoma dodecandrum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:17

    Topics: Apigenin; Chromatography; Chromatography, High Pressure Liquid; Dextrans; Flavanones; Flavonoids; Glycosides; Kaempferols; Luteolin; Magnoliopsida; Plants, Medicinal; Quercetin; Silica Gel

2014
[Simultaneous determination of four flavone C-glycosides in Phyllostachys edulis leaves by high-performance liquid chromatography with ultraviolet spectrometry].
    Guang pu xue yu guang pu fen xi = Guang pu, 2014, Volume: 34, Issue:9

    Topics: Apigenin; Chromatography, High Pressure Liquid; Flavones; Flavonoids; Glucosides; Glycosides; Luteolin; Monosaccharides; Plant Leaves; Poaceae; Spectrophotometry, Ultraviolet

2014
Effects of Mung Bean (Vigna radiata L.) Ethanol Extracts Decrease Proinflammatory Cytokine-Induced Lipogenesis in the KK-Ay Diabese Mouse Model.
    Journal of medicinal food, 2015, Volume: 18, Issue:8

    Topics: 3T3-L1 Cells; Adipose Tissue, White; Animals; Apigenin; Body Weight; Chemokine CCL2; Cholesterol; Cytokines; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Ethanol; Fabaceae; Inflammation; Interleukin-6; Lipogenesis; Male; MAP Kinase Signaling System; Mice; Obesity; Plant Extracts; Triglycerides

2015
Effects of germination on the nutritional properties, phenolic profiles, and antioxidant activities of buckwheat.
    Journal of food science, 2015, Volume: 80, Issue:5

    Topics: Antioxidants; Apigenin; Diet; Fagopyrum; Flavones; Flavonoids; Functional Food; Germination; Glucosides; Humans; Nutritive Value; Oxidation-Reduction; Phenols; Rutin; Seeds

2015
Pharmacokinetics and tissue distribution study of Isovitexin in rats by HPLC-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Jun-01, Volume: 991

    Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apigenin; Area Under Curve; Chromatography, High Pressure Liquid; Limit of Detection; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tissue Distribution

2015
The phytochemical investigation of Agrimonia eupatoria L. and Agrimonia procera Wallr. as valid sources of Agrimoniae herba--The pharmacopoeial plant material.
    Journal of pharmaceutical and biomedical analysis, 2015, Oct-10, Volume: 114

    Topics: Agrimonia; Apigenin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Germany; Hydrolyzable Tannins; Mass Spectrometry; Phytochemicals; Plant Extracts; Plants, Medicinal; Solvents; Spectrophotometry, Ultraviolet; Tannins

2015
Acylation of Antioxidant of Bamboo Leaves with Fatty Acids by Lipase and the Acylated Derivatives' Efficiency in the Inhibition of Acrylamide Formation in Fried Potato Crisps.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Acrylamide; Acylation; Antioxidants; Apigenin; Fatty Acids; Flavonoids; Food Handling; Fungal Proteins; Glucosides; Lauric Acids; Lipase; Luteolin; Pentanols; Plant Extracts; Plant Leaves; Sasa; Solanum tuberosum

2015
The glycosylated flavonoids vitexin, isovitexin, and quercetrin isolated from Serjania erecta Radlk (Sapindaceae) leaves protect PC12 cells against amyloid-β25-35 peptide-induced toxicity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2015, Volume: 86

    Topics: Amyloid beta-Peptides; Animals; Apigenin; Molecular Structure; Nitric Oxide; PC12 Cells; Peptide Fragments; Plant Leaves; Quercetin; Rats; Sapindaceae

2015
Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways.
    International journal of biological sciences, 2016, Volume: 12, Issue:1

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Apigenin; Cells, Cultured; Heme Oxygenase-1; Humans; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Signal Transduction

2016
[Chemical Constituents from Leaves of Hibiscus syriacus and Their α-Glucosidase Inhibitory Activities].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:5

    Topics: alpha-Glucosidases; Apigenin; Glucosides; Glycoside Hydrolase Inhibitors; Hibiscus; Kaempferols; Luteolin; Oleanolic Acid; Phytochemicals; Plant Leaves; Sitosterols; Stigmasterol; Triterpenes

2015
Passiflora actinia hydroalcoholic extract and its major constituent, isovitexin, are neuroprotective against glutamate-induced cell damage in mice hippocampal slices.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:2

    Topics: Animals; Apigenin; Cell Survival; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Mice; Neuroprotective Agents; Passiflora; Plant Extracts; Plant Leaves

2016
Gentiana lutea exerts anti-atherosclerotic effects by preventing endothelial inflammation and smooth muscle cell migration.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2016, Volume: 26, Issue:4

    Topics: Animals; Aorta; Apigenin; Arteriosclerosis; Becaplermin; Cell Movement; Cholesterol; Diabetes Mellitus, Experimental; Gentiana; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type II; Phospholipase C gamma; Plant Roots; Proto-Oncogene Proteins c-sis; Rats; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2016
LC-MS analysis of phenolic compounds and antioxidant activity of buckwheat at different stages of malting.
    Food chemistry, 2016, Nov-01, Volume: 210

    Topics: Apigenin; Chromatography, Liquid; Fagopyrum; Flavonoids; Germination; Glucosides; Mass Spectrometry; Methanol; Oxidation-Reduction; Phenols; Plant Extracts; Rutin; Seeds

2016
Changes of primary and secondary metabolites in barley plants exposed to CdO nanoparticles.
    Environmental pollution (Barking, Essex : 1987), 2016, Volume: 218

    Topics: Amino Acids; Apigenin; Cadmium Compounds; Coumaric Acids; Hordeum; Nanoparticles; Oxides; Phenols; Plant Leaves; Plant Roots; Secondary Metabolism; Soil Pollutants; Water Pollutants

2016
Simultaneous quantification and identification of flavonoids, lignans, coumarin and amides in leaves of Zanthoxylum armatum using UPLC-DAD-ESI-QTOF-MS/MS.
    Journal of pharmaceutical and biomedical analysis, 2017, Jan-05, Volume: 132

    Topics: Amides; Apigenin; Benzodioxoles; Catechin; Chromatography, High Pressure Liquid; Coumarins; Dioxoles; Flavonoids; Furans; Hesperidin; Hydroxybenzoates; Lignans; Limit of Detection; Plant Leaves; Powders; Reproducibility of Results; Seasons; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Zanthoxylum

2017
Homogenate-assisted Vacuum-powered Bubble Extraction of Moso Bamboo Flavonoids for On-line Scavenging Free Radical Capacity Analysis.
    Molecules (Basel, Switzerland), 2017, Jul-11, Volume: 22, Issue:7

    Topics: Antioxidants; Apigenin; Chromatography, High Pressure Liquid; Flavonoids; Free Radical Scavengers; Free Radicals; Glucosides; Humans; Luteolin; Plant Extracts; Plant Leaves; Poaceae; Vacuum

2017
Isovitexin (IV) induces apoptosis and autophagy in liver cancer cells through endoplasmic reticulum stress.
    Biochemical and biophysical research communications, 2018, 02-19, Volume: 496, Issue:4

    Topics: Antineoplastic Agents; Apigenin; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Hep G2 Cells; Humans; Liver Neoplasms; Mitochondria, Liver; Mitochondrial Proteins

2018
Enzymatic inhibitory activity of
    Natural product research, 2019, Volume: 33, Issue:12

    Topics: Apigenin; Catalytic Domain; Cell Line; Cell Movement; Drug Evaluation, Preclinical; Ficus; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 8; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Molecular Docking Simulation; Molecular Dynamics Simulation; Plant Extracts; Plant Leaves

2019
Changes in isovitexin-O-glycosylation during the development of young barley plants.
    Phytochemistry, 2018, Volume: 148

    Topics: Apigenin; Chromatography, High Pressure Liquid; Flavones; Flavonoids; Glucosides; Glucosyltransferases; Glycosylation; Hordeum; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves

2018
[Effects of isovitexin on transient outward potassium current of ventricular myocytes in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:24

    Topics: Animals; Apigenin; Heart Ventricles; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels; Rats; Transient Receptor Potential Channels

2017
Isovitexin alleviates liver injury induced by lipopolysaccharide/d-galactosamine by activating Nrf2 and inhibiting NF-κB activation.
    Microbial pathogenesis, 2018, Volume: 119

    Topics: Animals; Apigenin; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Galactosamine; Gene Expression Regulation; Heme Oxygenase-1; Lipopolysaccharides; Liver; Liver Function Tests; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; Oryza; Phosphorylation; Plant Extracts; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation

2018
Indirect and direct routes to C-glycosylated flavones in Saccharomyces cerevisiae.
    Microbial cell factories, 2018, Jul-09, Volume: 17, Issue:1

    Topics: Apigenin; Biosynthetic Pathways; Flavanones; Flavones; Glycosides; Glycosylation; Glycosyltransferases; Luteolin; Monosaccharides; Plant Proteins; Saccharomyces cerevisiae

2018
[Study on Chemical Components of Tripterospermum chinense ( Ⅱ)].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2016, Volume: 39, Issue:3

    Topics: Apigenin; Benzaldehydes; Drugs, Chinese Herbal; Gentianaceae; Iridoid Glucosides

2016
Chemical constituents and allelopathic activity of
    Natural product research, 2020, Volume: 34, Issue:6

    Topics: Allelopathy; Apigenin; Chromatography, High Pressure Liquid; Fabaceae; Flavonoids; Luteolin; Plant Extracts; Plant Leaves; Plant Roots

2020
Influence of Luehea divaricata Mart. extracts on peripheral vascular resistance and the role of nitric oxide and both Ca
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Mar-15, Volume: 56

    Topics: Animals; Apigenin; Brazil; Female; Glyburide; KATP Channels; Malvaceae; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase; Organ Culture Techniques; Plant Extracts; Plants, Medicinal; Rats, Wistar; Vascular Resistance; Vasodilation; Vasodilator Agents

2019
Use of ion mobility mass spectrometry to enhance cumulative analytical specificity and separation to profile 6-C/8-C-glycosylflavone critical isomer pairs and known-unknowns in medicinal plants.
    Phytochemical analysis : PCA, 2019, Volume: 30, Issue:4

    Topics: Apigenin; Chromatography, High Pressure Liquid; Flavones; Flavonoids; Glucosides; Glycosides; Isomerism; Luteolin; Mass Spectrometry; Passiflora; Phytochemicals; Plant Extracts; Plants, Medicinal

2019
A newly isolated human intestinal bacterium strain capable of deglycosylating flavone C-glycosides and its functional properties.
    Microbial cell factories, 2019, May-28, Volume: 18, Issue:1

    Topics: Adult; Apigenin; Carbon; Enterococcus faecalis; Feces; Flavones; Flavonoids; Gastrointestinal Microbiome; Glucosides; Glycosides; Humans; Intestines; Male; RNA, Ribosomal, 16S; Sequence Analysis, RNA

2019
Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1.
    Journal of experimental & clinical cancer research : CR, 2019, Jun-17, Volume: 38, Issue:1

    Topics: Animals; Apigenin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Male; Mice; Mice, Nude; Neoplastic Stem Cells; Promoter Regions, Genetic; Superoxide Dismutase; Xenograft Model Antitumor Assays

2019
Identification and Characterization of Apigenin 6-C-Glucosyltransferase Involved in Biosynthesis of Isosaponarin in Wasabi (Eutrema japonicum).
    Plant & cell physiology, 2019, Dec-01, Volume: 60, Issue:12

    Topics: Acetamides; Apigenin; Flowers; Glucosides; Glucosyltransferases; Phylogeny; Plant Leaves; Triterpenes; Wasabia

2019
Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Adenylate Kinase; Animals; Anti-Inflammatory Agents; Apigenin; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cell Differentiation; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microglia; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Signal Transduction

2019
Quantitative and Chemical Fingerprint Analysis of Desmodium styracifolium by High-Performance Liquid Chromatography Combined with Chemometrics.
    Journal of chromatographic science, 2020, Apr-23, Volume: 58, Issue:4

    Topics: Apigenin; Cheminformatics; China; Chromatography, High Pressure Liquid; Cluster Analysis; Fabaceae; Glycosides; Limit of Detection; Plants, Medicinal; Principal Component Analysis; Sensitivity and Specificity

2020
Isovitexin protects against cisplatin-induced kidney injury in mice through inhibiting inflammatory and oxidative responses.
    International immunopharmacology, 2020, Volume: 83

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Apigenin; Blood Urea Nitrogen; Cisplatin; Creatinine; Cytokines; Female; Heme Oxygenase-1; Inflammation; Malondialdehyde; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Reactive Oxygen Species

2020
Metabolic profiling comparison of isovitexin in normal and kidney stone model rats by ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry.
    Journal of separation science, 2020, Volume: 43, Issue:12

    Topics: Animals; Apigenin; Chromatography, High Pressure Liquid; Disease Models, Animal; Kidney Calculi; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Time Factors

2020
Influence of fermentation on antioxidant and hypolipidemic properties of maifanite mineral water-cultured common buckwheat sprouts.
    Food chemistry, 2020, Aug-15, Volume: 321

    Topics: Animals; Antioxidants; Apigenin; Fagopyrum; Fermentation; Fermented Foods; Flavonoids; Glucosides; Hyperlipidemias; Lactobacillus plantarum; Male; Mice; Mineral Waters; Phenols; Rutin; Saccharomyces cerevisiae; Seedlings

2020
Isovitexin Inhibits Stemness and Induces Apoptosis in Hepatocellular Carcinoma SK-Hep-1 Spheroids by Upregulating miR-34a Expression.
    Anti-cancer agents in medicinal chemistry, 2020, Volume: 20, Issue:14

    Topics: Antineoplastic Agents; Apigenin; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; MicroRNAs; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured; Up-Regulation

2020
Treasure from garden: Bioactive compounds of buckwheat.
    Food chemistry, 2021, Jan-15, Volume: 335

    Topics: Apigenin; Fagopyrum; Flavonoids; Glucosides; Humans; Nutritive Value; Phytochemicals; Plant Extracts; Quercetin; Rutin; Seeds

2021
Isovitexin potentiated the antitumor activity of cisplatin by inhibiting the glucose metabolism of lung cancer cells and reduced cisplatin-induced immunotoxicity in mice.
    International immunopharmacology, 2021, Volume: 94

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apigenin; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cytokines; Down-Regulation; Drug Synergism; Glucose; Humans; Killer Cells, Natural; Lactic Acid; Lung Neoplasms; Male; Membrane Proteins; Mice, Nude; T-Lymphocytes, Cytotoxic; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2021
Protective effect of flavonoids from Passiflora edulis Sims on diabetic complications in rats.
    The Journal of pharmacy and pharmacology, 2021, Sep-07, Volume: 73, Issue:10

    Topics: Animals; Antioxidants; Apigenin; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Complications; Diabetes Mellitus, Experimental; Flavones; Flavonoids; Fructosamine; Glucosides; Glycosides; Luteolin; Male; Passiflora; Phytotherapy; Plant Extracts; Plant Leaves; Platelet Aggregation; Rats, Wistar; Tandem Mass Spectrometry

2021
Ficus deltoidea: Potential inhibitor of pro-inflammatory mediators in lipopolysaccharide-induced activation of microglial cells.
    Journal of ethnopharmacology, 2021, Oct-28, Volume: 279

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apigenin; Cell Line; Dose-Response Relationship, Drug; Ficus; Inflammation Mediators; Lipopolysaccharides; Mice; Microglia; Neuroinflammatory Diseases; Neuroprotective Agents; NF-kappa B; Plant Extracts; Plant Leaves

2021
Isovitexin Suppresses Stemness of Lung Cancer Stem-Like Cells through Blockage of MnSOD/CaMKII/AMPK Signaling and Glycolysis Inhibition.
    BioMed research international, 2021, Volume: 2021

    Topics: A549 Cells; Adenylate Kinase; Animals; Apigenin; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Cell Survival; Glycolysis; Humans; Lactic Acid; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Signal Transduction; Superoxide Dismutase; Wound Healing

2021
Isovitexin attenuates tumor growth in human colon cancer cells through the modulation of apoptosis and epithelial-mesenchymal transition via PI3K/Akt/mTOR signaling pathway.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2021, Volume: 99, Issue:6

    Topics: Apigenin; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Epithelial-Mesenchymal Transition; Humans; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases

2021
Isovitexin Is a Direct Inhibitor of
    Journal of microbiology and biotechnology, 2021, Oct-28, Volume: 31, Issue:10

    Topics: Apigenin; Binding Sites; Cell Line; Coagulase; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Staphylococcus aureus; Structure-Activity Relationship

2021
Isovitexin alleviates acute gouty arthritis in rats by inhibiting inflammation via the TLR4/MyD88/NF-κB pathway.
    Pharmaceutical biology, 2021, Volume: 59, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apigenin; Arthritis, Gouty; Colchicine; Disease Models, Animal; Inflammation; Male; Myeloid Differentiation Factor 88; NF-kappa B; Rats; Rats, Sprague-Dawley; Sulfonamides; Toll-Like Receptor 4

2021
Adiponectin receptors by increasing mitochondrial biogenesis and respiration promote osteoblast differentiation: Discovery of isovitexin as a new class of small molecule adiponectin receptor modulator with potential osteoanabolic function.
    European journal of pharmacology, 2021, Dec-15, Volume: 913

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Apigenin; Cell Differentiation; Cells, Cultured; Energy Metabolism; Mice; Mitochondria; Osteoblasts; Osteogenesis; Oxidative Phosphorylation; Primary Cell Culture; Receptors, Adiponectin; Up-Regulation

2021
Screening of bioactive ingredients of Tsantan Sumtang in ameliorating H9c2 cells injury.
    Journal of ethnopharmacology, 2022, Mar-01, Volume: 285

    Topics: Animals; Antibiotics, Antineoplastic; Apigenin; Cell Line; Dose-Response Relationship, Drug; Doxorubicin; Eugenol; Hydrogen Peroxide; Medicine, Tibetan Traditional; Myoblasts; Myocardial Ischemia; Phytotherapy; Polyphenols; Quercetin; Rats; Rats, Sprague-Dawley

2022
Vitexin and Isovitexin Act through Inhibition of Insulin Receptor to Promote Longevity and Fitness in Caenorhabditis elegans.
    Molecular nutrition & food research, 2022, Volume: 66, Issue:17

    Topics: Animals; Apigenin; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Forkhead Transcription Factors; Humans; Insulin; Longevity; Molecular Docking Simulation; Receptor, Insulin

2022
Oral Administration of Isovitexin, a Naturally Occurring Apigenin Derivative Showed Osteoanabolic Effect in Ovariectomized Mice: A Comparative Study with Teriparatide.
    Calcified tissue international, 2022, Volume: 111, Issue:2

    Topics: Administration, Oral; Anabolic Agents; Animals; Apigenin; Bone Density; Female; Mice; Osteogenesis; Ovariectomy; Teriparatide

2022
Isovitexin restores sevoflurane‑induced cognitive dysfunction by mediating autophagy through activation of the PGC‑1α/FNDC5 signaling pathway.
    Acta neurobiologiae experimentalis, 2022, Volume: 82, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apigenin; Apoptosis; Autophagy; Cognitive Dysfunction; Fibronectins; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; Sevoflurane; Signal Transduction

2022