isovaline has been researched along with 4-aminopyridine in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calos, M; Carlen, PL; Puil, E; Shin, DS; Sutton, A; Yu, W | 1 |
| Pilitsis, J; Shin, DS; Smith, AB; Yu, W | 1 |
2 other study(ies) available for isovaline and 4-aminopyridine
| Article | Year |
|---|---|
Isovaline, a rare amino acid, has anticonvulsant properties in two in vitro hippocampal seizure models by increasing interneuronal activity.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Interneurons; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Seizures; Valine | 2011 |
Isovaline attenuates epileptiform activity and seizure behavior in 4-aminopyridine treated rats.
Topics: 4-Aminopyridine; Action Potentials; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Hippocampus; Infusions, Intravenous; Rats; Rats, Sprague-Dawley; Seizures; Treatment Outcome; Valine | 2014 |