isotretinoin and drospirenone

Acne affects a large proportion of the Canadian population and has psychosocial and financial consequences.. We provide cost information for treatments recommended by the Canadian acne guidelines.. Highest level recommendations were selected for 3-month usage cost.. Three-month estimated treatment costs were as follows: topical retinoids ($14.40-$73.80), benzoyl peroxide (BPO; $6.75), fixed-dose BPO-clindamycin ($40.95-$44.10) and BPO-adapalene ($73.80), oral antibiotics ($25.20 for tetracycline 250 mg qid; $52.20 and $52.74 for doxycycline 50 mg bid and 100 mg od, respectively), and hormonal therapy ($26.46-$37.80 for ethinyl estradiol [EE] 0.030 mg/drospirenone 3mg and $75.60-108.99 for EE 0.035 mg/cyproterone acetate 2 mg). Oral isotretinoin 3-month costs ranged from $393.96 to $478.80.. Awareness of costs of recommended treatments may facilitate improved outcomes by increasing procurement and adherence.

Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Administration, Oral; Androgen Antagonists; Androstenes; Anti-Bacterial Agents; Benzoyl Peroxide; Canada; Clindamycin; Cyproterone Acetate; Dermatologic Agents; Doxycycline; Drug Combinations; Estrogens; Ethinyl Estradiol; Humans; Isotretinoin; Mineralocorticoid Receptor Antagonists; Minocycline; Practice Guidelines as Topic; Severity of Illness Index; Tetracycline