isosungucine and indole

isosungucine has been researched along with indole* in 1 studies

Other Studies

1 other study(ies) available for isosungucine and indole

Article	Year
Concise Syntheses of bis-Strychnos Alkaloids (-)-Sungucine, (-)-Isosungucine, and (-)-Strychnogucine B from (-)-Strychnine. Chemistry (Weinheim an der Bergstrasse, Germany), 2016, Aug-08, Volume: 22, Issue:33 The first chemical syntheses of complex, bis-Strychnos alkaloids (-)-sungucine (1), (-)-isosungucine (2), and (-)-strychnogucine B (3) from (-)-strychnine (4) is reported. Key steps included (1) the Polonovski-Potier activation of strychnine N-oxide; (2) a biomimetic Mannich coupling to forge the signature C23-C5' bond that joins two monoterpene indole monomers; and (3) a sequential HBr/NaBH3 CN-mediated reduction to fashion the ethylidene moieties in 1-3. DFT calculations were employed to rationalize the regiochemical course of reactions involving strychnine congeners. Topics: Alkaloids; Cyclic N-Oxides; Indole Alkaloids; Indoles; Stereoisomerism; Strychnine; Strychnos	2016

Article

Year

Concise Syntheses of bis-Strychnos Alkaloids (-)-Sungucine, (-)-Isosungucine, and (-)-Strychnogucine B from (-)-Strychnine.

Chemistry (Weinheim an der Bergstrasse, Germany), 2016, Aug-08, Volume: 22, Issue:33

The first chemical syntheses of complex, bis-Strychnos alkaloids (-)-sungucine (1), (-)-isosungucine (2), and (-)-strychnogucine B (3) from (-)-strychnine (4) is reported. Key steps included (1) the Polonovski-Potier activation of strychnine N-oxide; (2) a biomimetic Mannich coupling to forge the signature C23-C5' bond that joins two monoterpene indole monomers; and (3) a sequential HBr/NaBH3 CN-mediated reduction to fashion the ethylidene moieties in 1-3. DFT calculations were employed to rationalize the regiochemical course of reactions involving strychnine congeners.

Topics: Alkaloids; Cyclic N-Oxides; Indole Alkaloids; Indoles; Stereoisomerism; Strychnine; Strychnos

2016