isospaglumic acid has been researched along with zj43 in 4 studies
| Studies (isospaglumic acid) | Trials (isospaglumic acid) | Recent Studies (post-2010) (isospaglumic acid) | Studies (zj43) | Trials (zj43) | Recent Studies (post-2010) (zj43) |
|---|---|---|---|---|---|
| 469 | 31 | 116 | 20 | 0 | 11 |
| Protein | Taxonomy | isospaglumic acid (IC50) | zj43 (IC50) |
|---|---|---|---|
| Glutamate carboxypeptidase 2 | Homo sapiens (human) | 0.0057 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alquicer, G; Bařinka, C; Byun, Y; Kim, HJ; Konvalinka, J; Lubkowski, J; Mease, R; Mlčochová, P; Navrátil, M; Němcová, A; Plechanovová, A; Pomper, M; Rulíšek, L; Skultétyová, L | 1 |
| Kozikowski, A; Neale, JH; Yamamoto, T; Zhou, J | 1 |
| Adedoyin, MO; Neale, JH; Vicini, S | 1 |
| Borst, P; de Haas, M; Jansen, RS; Mahakena, S; van de Wetering, K | 1 |
4 other study(ies) available for isospaglumic acid and zj43
| Article | Year |
|---|---|
Novel substrate-based inhibitors of human glutamate carboxypeptidase II with enhanced lipophilicity.
Topics: Antigens, Surface; Binding Sites; Crystallography, X-Ray; Dipeptides; Glutamate Carboxypeptidase II; Humans; Kinetics; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Quantum Theory; Structure-Activity Relationship; Substrate Specificity; Thermodynamics | 2011 |
Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain.
Topics: Analgesics; Animals; Dipeptides; Glutamate Carboxypeptidase II; Inflammation Mediators; Injections, Intraventricular; Male; Organophosphorus Compounds; Pain; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Urea | 2008 |
Endogenous N-acetylaspartylglutamate (NAAG) inhibits synaptic plasticity/transmission in the amygdala in a mouse inflammatory pain model.
Topics: Amygdala; Animals; Behavior, Animal; Dipeptides; Disease Models, Animal; Excitatory Postsynaptic Potentials; Formaldehyde; Glutamate Carboxypeptidase II; Hyperalgesia; In Vitro Techniques; Inflammation; Mice; Models, Biological; Neuronal Plasticity; Nociceptors; Pain; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Urea | 2010 |
ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs.
Topics: Animals; Brain; Dipeptides; Humans; Kainic Acid; Mice; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nerve Tissue Proteins; Urea | 2015 |