Page last updated: 2024-09-05

isospaglumic acid and n-acetylaspartic acid

isospaglumic acid has been researched along with n-acetylaspartic acid in 145 studies

Compound Research Comparison

Studies (isospaglumic acid)	Trials (isospaglumic acid)	Recent Studies (post-2010) (isospaglumic acid)	Studies (n-acetylaspartic acid)	Trials (n-acetylaspartic acid)	Recent Studies (post-2010) (n-acetylaspartic acid)
469	31	116	3,689	227	1,143

Research

Studies (145)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (6.21)	18.7374
1990's	33 (22.76)	18.2507
2000's	53 (36.55)	29.6817
2010's	48 (33.10)	24.3611
2020's	2 (1.38)	2.80

Authors

Authors	Studies
Miyake, M; Morino, H	1
Bruhn, H; Frahm, J; Gyngell, ML; Hänicke, W; Merboldt, KD; Michaelis, T	1
Coyle, JT; Hedreen, JC; Kuncl, R; Rothstein, JD; Sim, L; Stauch-Slusher, B; Tsai, GC	1
Coyle, JT; Frondoza, CG; Simmons, ML	1
Cangro, CB; Moffett, JR; Namboodiri, MA; Neale, JH	1
Korf, J; Veenma-van der Duin, L; Venema, K; Wolf, JH	1
Brancati, A; D'Arcangelo, P	2
Clawson, L; Cornblath, DR; Coyle, JT; Drachman, DB; Kuncl, RW; Pestronk, A; Rothstein, JD; Stauch, BL; Tsai, G	1
Abreu, M; Blakely, R; Carpenter, DO; Coyle, JT; ffrench-Mullen, JM; Fisher, R; Koller, KJ; Ory-Lavollée, L; Zaczek, R	1
Anderson, KJ; Borja, MA; Cotman, CW; Moffett, JR; Namboodiri, MA; Neale, JH	1
Blakely, RD; Coyle, JT; Ory-Lavollée, L	2
Coyle, JT; Koller, KJ	1
Coyle, JT; Koller, KJ; Zaczek, R	1
Kakimoto, Y; Miyake, M; Mizobuchi, M; Morino, H	1
Kakimoto, Y; Miyake, M; Sorimachi, M	1
Kakimoto, Y; Miyake, M	1
Moffett, JR; Namboodiri, MA	1
Bedell, BJ; Doyle, TJ; Narayana, PA	1
Jaarsma, D; Korf, J; Veenma-van der Duin, L	1
Garber, HJ; Oldendorf, WH; Stoller, BE; Tishler, TA	1
Burlina, AB; Burlina, AP; Ferrari, V; Leon, A; Mazza, MR; Skaper, SD	1
Moffett, JR; Namboodiri, MA; Neale, JH	1
Bruhn, H; Frahm, J; Hänicke, W; Merboldt, KD; Michaelis, T	1
Constantakakis, E; Plaitakis, A	1
Canioni, P; Labouesse, J; Martin, M; Merle, M	1
Butler, IJ; Caprioli, RM; Lin, SN; Slopis, JM	1
Bhakoo, KK; Florian, CL; Noble, MD; Williams, SR	1
Comair, YG; Hong, SC; Lüders, HO; Najm, IM; Ng, TC; Wang, Y	1
Frahm, J; Pouwels, PJ	2
Burlina, AB; Burlina, AP; Facci, L; Ferrari, V; Skaper, SD	1
Carter, RE; Coyle, JT; Passani, LA; Vonsattel, JP	1
Sutherland, GR; Tyson, RL	1
Baer, L; Chang, RW; Coyle, JT; Flood, J; Goff, DC; Tsai, G	1
Bolo, N; Dahchour, A; De Witte, P; Durbin, P; Macher, JP; Muzet, M; Nédélec, JF	1
Faull, KF; Marsh, L; Pascoe, N; Pfefferbaum, A; Rafie, R	1
Ageta, T; Kodama, H; Ma, D; Nakayama, K; Sugahara, K; Zhang, J	1
Barker, GJ; Davie, CA; Leary, SM; Miller, DH; Parker, GJ; Stevenson, VL; Thompson, AJ; Wang, L	1
Frahm, J; Helms, G	1
Ito, M; Kato, T; Nishina, M; Takashima, S	1
Bonafé, L; Burlina, AB; Burlina, AP; Ferrari, V; Suppiej, A; Zacchello, F	1
Baslow, MH	2
Barker, GJ; Duncan, JS; McLean, MA; Woermann, FG	1
Barker, GJ; Bartlett, PA; Duncan, JS; McLean, MA; Woermann, FG	1
Capone, A; Hennig, J; Martin, E; Schneider, J; Thiel, T	1
Barker, GJ; Duncan, JS; McLean, MA; Simister, RJ; Woermann, FG	1
Battistuta, J; Bjartmar, C; Trapp, BD	1
Gafurov, B; Grossfeld, RM; Lieberman, EM; Urazaev, AK	1
Battistuta, J; Bjartmar, C; Dupree, E; Terada, N; Trapp, BD	1
Heerschap, A; Kok, RD; Nijland, R; van den Berg, PP; van den Bergh, AJ	1
Bernsen, H; Boerman, R; Heerschap, A; Rijpkema, M; Schuuring, J; van der Graaf, M; van der Kogel, A; van der Meulen, Y	1
Brockmann, K; Dechent, P; Frahm, J; Hanefeld, F; Rusch, O; Wilken, B	1
Nudmamud, S; Reynolds, GP; Reynolds, LM	1
Balcar, VJ; Bubeníková, V; Fitzgibbon, T; Pliss, L; Pokorný, J; St'astný, F	1
Hurd, R; Nelson, SJ; Pelletier, D; Sailasuta, N; Srinivasan, R; Vigneron, DB	1
Hurd, R; Nelson, S; Sailasuta, N; Srinivasan, R; Vigneron, D	1
Bzdega, T; Gehl, LM; Neale, JH; Saab, OH; Wroblewska, B	1
Davie, CA; Lees, AJ; MacManus, D; Miller, DH; Miszkiel, KA; Page, RA; Schapira, AH; Walshe, JM	1
Cochran, SM; Morris, BJ; Pratt, JA; Reynolds, GP; Reynolds, LM	1
Juchem, C; Logothetis, NK; Merkle, H; Nauerth, A; Pfeuffer, J	1
Ambrosini, A; Colonnese, C; Garreffa, G; Giove, F; Guardati, M; Macrì, MA; Maraviglia, B	1
Tsai, SJ	1
Brockmann, K; Dechent, P; Frahm, J; Hanefeld, FA; Pouwels, PJ; Wilken, B	1
Brockmann, K; Dechent, P; Frahm, J; Groeschel, S; Hanefeld, F; Wilichowski, E	1
Moffett, JR; Namboodiri, AM	2
Coyle, JT	1
Baslow, MH; Guilfoyle, DN	2
Boltshauser, E; Burlina, AB; Burlina, AP; Engelke, U; Schmitt, B; Wevers, RA	1
Achreja, M; Lieberman, EM; Urazaev, AK	1
Calvin, D; Rojas, C; Slusher, BS; Thomas, AG; Tsukamoto, T; Vornov, J; Wozniak, KM; Wu, Y	1
Arun, P; Madhavarao, CN; Moffett, JR; Namboodiri, MA	1
Bönnemann, C; Brockmann, K; Dechent, P; Frahm, J; Hanefeld, F; Schreiber, G	1
Assadi, M; Bilaniuk, L; Francis, J; Freese, A; Haselgrove, J; Hurh, P; Janson, CG; Leone, P; McPhee, SW; Shera, D; Wang, DJ	1
Lavebratt, C; Spenger, C; Wahlund, LO; Westman, E	1
Doelken, M; Doerfler, A; Engelhorn, T; Ganslandt, O; Hammen, T; Kerling, F; Nimsky, C; Schwarz, M; Stadlbauer, A; Stefan, H	1
Barker, PB; Edden, RA; Pomper, MG	1
Charlton, RA; Howe, FA; Markus, HS; McIntyre, DJ	1
Gupta, S; Jiang, Y; Singh, AK	1
Baker, EH; Barker, PB; Basso, G; Bonekamp, D; Horská, A; Smith, MA	1
Cipolotti, L; Dalton, C; Fernando, K; Miller, DH; Ron, MA; Summers, M; Swanton, J	1
Benarroch, EE	1
Danielsen, ER; Dock, J; Elberling, TV; Feldt-Rasmussen, U; Hørding, M; Perrild, H; Rasmussen, AK; Thomsen, C; Waldemar, G	1
Barker, GJ; Duncan, JS; McLean, MA; Salmenpera, TM; Simister, RJ	1
Bargallo, N; Botet, F; Caldu, X; Falcon, C; Gimenez, M; Junque, C; Mercader, JM; Narberhaus, A; Soria-Pastor, S	1
Arun, P; Madhavarao, CN; Moffett, JR; Namboodiri, AM	1
Arai, K; Fukushima, T; Mitsuhashi, S; Sasaki, T; Tomiya, M; Toyo'oka, T	1
Gröhn, H; Gröhn, OH; Immonen, RJ; Kharatishvili, I; Niskanen, JP; Pitkänen, A	1
Atkins, A; Dawson, LA; de la Flor, R; Shah, AJ; Slone-Murphy, J	1
de Mattos Dutra, A; Dutra-Filho, CS; Henn, NT; Pederzolli, CD; Rockenbach, FJ; Romagna, EC; Sgaravatti, AM; Wajner, M; Wannmacher, CM; Wyse, AT; Zanin, FR	1
Attwell, D; Hamilton, NB; Káradóttir, R; Kolodziejczyk, K; Wade, A	1
Ende, G; Hoerst, M; Meyer-Lindenberg, A; Tunc-Skarka, N; Weber-Fahr, W; Zink, M	1
Arun, P; Moffett, JR; Namboodiri, AM	1
Reynolds, GP; Reynolds, LM	1
Danishad, KA; Jagannathan, NR; Kadhiravan, T; Mishra, H; Mishra, HK; Reddy, VV; Sharma, H; Sharma, SK; Sharma, U; Sinha, S; Sreenivas, V	1
Arvanitis, D; Bokemeyer, M; Ding, XQ; Goldbecker, A; Heeren, M; Lanfermann, H; Raab, P; Tillmann, HL; Weissenborn, K	1
Igarashi, H; Nakada, T; Nishizawa, M; Okamoto, K; Ozawa, T; Shimohata, T; Takado, Y; Terajima, K	1
Clark, VP; Coffman, BA; Gasparovic, C; Trumbo, MC	1
Bacci, A; Feraco, P; Leonardi, M; Malavolta, N; Passamonti, L; Pedrabissi, F; Zampogna, G	1
Behar, KL; Gomez, R; Guidone, E; Gulanski, B; Jiang, L; Koretski, J; Krystal, JH; Mason, GF; Petrakis, IL; Pittman, B; Sanacora, G; Watzl, J; Weinzimer, SA	1
Caplan, R; Hudkins, M; Levitt, J; O'Neill, J; Seese, RR; Siddarth, P; Tseng, B; Wu, KN	1
Block, W; Fingerhut, N; Jessen, F; Kühn, KU; Maier, W; Petrovsky, N; Schild, HH; Sprinkart, AM; Träber, F; Wagner, M	1
Fei, S; Ji, Y; Rao, S; Wang, H; Yao, X; Zeng, M	1
Bao, Y; Guo, J; Liu, C; Lu, X; Niu, B; Wang, F; Wang, J; Wang, L; Wu, L; Xie, H; Zhang, T; Zhao, H; Zou, J	1
Aoki, I; Barkovich, AJ; Inoue, K; Ito, Y; Saito, S; Takanashi, J	1
Hooper, SR; Keshavan, MS; Kwapil, TR; Schoch, K; Shashi, V; Stanley, JA; Veerapandiyan, A; Zapadka, M	1
Castellano, G; Covolan, RJ; Dias, CS; Foerster, B; Li, LM	1
Connor, J; Ennis, K; Felt, B; Georgieff, MK; Hurst, A; Rao, R; Schallert, T; Tkac, I; Unger, EL	1
Horita, DA; Kleven, GA; Morgan, JJ; Olson, J; Ronca, AE; Tulbert, CD	1
Carey, PD; Ferrett, HL; Renshaw, PF; Spottiswoode, BS; Stein, DJ; Sung, YH; Yurgelun-Todd, DA	1
Card, D; Moore, AM; Nossin-Manor, R; Raybaud, C; Sled, JG; Taylor, MJ	1
Andrews-Shigaki, B; Ariyannur, PS; Arun, P; Barry, ES; Bosomtwi, A; Grunberg, NE; Moffett, JR; Namboodiri, AM; Selwyn, R; Tang, H	1
Jaworski, DM; Lawler, SE; Long, PM; Moffett, JR; Namboodiri, AMA; Viapiano, MS	1
Casseb, RF; Castellano, G; Cendes, F; D'Abreu, A; Lopes-Cendes, I; Ruocco, HH	1
Ally, BA; Donahue, MJ; Hussey, E; Mason, E; Pradhan, S; Rane, S; Waddell, KW	1
Fu, K; Furukawa-Hibi, Y; Iegaki, N; Ishikawa, Y; Miyamoto, Y; Muramatsu, S; Nabeshima, T; Nitta, A; Sato, K; Sumi, K; Uno, K	1
Fievisohn, EM; Hardy, WN; Sajja, VS; Vandevord, PJ	1
Abulseoud, OA; Baruth, JM; Choi, DS; Croarkin, PE; Frye, MA; Port, JD; Thomas, MA	1
Breet, E; Hattingh, CJ; Howells, FM; Lochner, C; Stein, DJ; Syal, S	1
Auer, MK; Bidlingmaier, M; Biedermann, SV; Bielohuby, M; Deussing, J; Ende, G; Falfán-Melgoza, C; Fuss, J; Gass, P; Jakovcevski, M; Lenz, JN; Pfister, F; Sack, M; Stalla, GK; Steinle, J; Weber-Fahr, W	1
Dubovický, M; Kašparová, S; Kucharská, J; Liptaj, T; Lipták, B; Sumbalová, Z; Szomolányi, P; Trattnig, S; Tušková, R; Uličná, O; Vančová, O	1
Berneman, Z; Daans, J; Guglielmetti, C; Hens, N; Kara, F; Orije, J; Ponsaerts, P; Praet, J; Santermans, E; Van der Linden, A; Verhoye, M	1
Castellano, G; Covolan, RJ; Edden, RA; Foerster, B; Landim, RC; Li, LM	1
Alt, J; Hollinger, KR; Kaplin, AI; Riehm, AM; Slusher, BS	1
Brennan, L; Garg, L; Garg, R; Gibney, MJ; Price, RK; Shewry, PR; Strain, JJ; Wallace, JM; Ward, JL; Welch, RW	1
Barker, PB; Brandt, AS; Churchill, G; Edden, RA; Harris, AD; Hua, J; Lim, IA; Margolis, RL; Pradhan, S; Ross, CA; Unschuld, PG; van Zijl, PC	1
Barker, PB; Chan, KL; Edden, RA; Puts, NA; Schär, M	1
Bairwa, D; Das, BK; Jagannathan, NR; Kumar, V; Pandey, RM; Sharma, SK; Sinha, S; Srivastava, AK; Vyas, S	1
Brockmann, K; Dechent, P; Gärtner, J; Krause, C; Ohlenbusch, A; Rosewich, H	1
Álvarez-Linera, J; Benito-León, J; Dydak, U; Hernández-Tamames, JA; Louis, ED; Malpica, N; Matarazzo, M; Mato-Abad, V; Molina-Arjona, JA; Romero, JP; Sánchez-Ferro, Á	1
Bond, DJ; Honer, WG; Lam, RW; Lang, DJ; MacMillan, EL; Silveira, LE; Su, W; Torres, IJ; Yatham, LN	1
Barker, PB; Chan, KL; Edden, RAE; Oeltzschner, G; Saleh, MG	1
Deelchand, DK; Grant, A; Hemmy, LS; Hodges, J; Marjańska, M; McCarten, JR; Terpstra, M	1
Barbieri, MA; Cavalli, RC; Del-Ben, CM; Figueiredo, FP; Rosa, CE; Salmon, CEG; Santos, AC; Schaufelberger, MS; Soares, JC	1
Brügger, M; de Matos, NMP; Ettlin, DA; Hock, A; Wyss, M	1
Azuma, S; Fu, K; Iegaki, N; Ishikawa, Y; Miyamoto, Y; Muramatsu, SI; Nitta, A; Sumi, K; Uno, K	1
Chen, Y; Gao, W; Li, Q; Liu, S; Liu, W; Shen, Z; Wu, R; Zhang, G	1
Barker, PB; Coughlin, JM; Crawford, JL; DuBois, SL; Nestadt, G; Nucifora, FC; Nucifora, LG; Pradhan, S; Sawa, A; Schretlen, DJ; Sedlak, TW; Trivedi, A; Wang, AM	1
Abdelkefi, I; Dhamala, E; Hennessy, TJ; Nadeau, H; Near, J; Nguyen, M	1
Andziak, P; Ciaś, M; Mruk, B; Paluch, Ł; Sklinda, K; Surowiecka, A; Walecki, J	1
Aida, N; Fujii, Y; Morisaki, N; Niwa, T; Piedvache, A; Shibasaki, J; Tomiyasu, M; Toyoshima, K	1

Reviews

7 review(s) available for isospaglumic acid and n-acetylaspartic acid

Article	Year
Functions of N-acetyl-L-aspartate and N-acetyl-L-aspartylglutamate in the vertebrate brain: role in glial cell-specific signaling. Journal of neurochemistry, 2000, Volume: 75, Issue:2 Topics: Animals; Aspartic Acid; Brain; Dipeptides; Humans; Neuroglia; Neurons; Neurotransmitter Agents; Signal Transduction; Vertebrates	2000
Central N-acetyl aspartylglutamate deficit: a possible pathogenesis of schizophrenia. Medical science monitor : international medical journal of experimental and clinical research, 2005, Volume: 11, Issue:9 Topics: Animals; Aspartic Acid; Brain; Dipeptides; Glutamic Acid; Humans; Models, Neurological; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2005
Preface: a brief review of N-acetylaspartate. Advances in experimental medicine and biology, 2006, Volume: 576 Topics: Animals; Aspartic Acid; Canavan Disease; Dipeptides; Energy Metabolism; Humans; Magnetic Resonance Spectroscopy; Myelin Sheath; Neurons; Osmolar Concentration	2006
A brief overview of N-acetylaspartate and N-acetylaspartylglutamate. Advances in experimental medicine and biology, 2006, Volume: 576 Topics: Animals; Aspartic Acid; Dipeptides; Neurons	2006
Functions of N-acetylaspartate and N-acetylaspartylglutamate in brain: evidence of a role in maintenance of higher brain integrative activities of information processing and cognition. Advances in experimental medicine and biology, 2006, Volume: 576 Topics: Aminohydrolases; Animals; Aspartic Acid; Blood Vessels; Brain; Cerebrovascular Circulation; Cognition; Dipeptides; Electronic Data Processing; Glucose; Glutamate Carboxypeptidase II; Neurons	2006
Glutamate carboxypeptidase II (NAALADase) inhibition as a novel therapeutic strategy. Advances in experimental medicine and biology, 2006, Volume: 576 Topics: Analgesics; Animals; Aspartic Acid; Dipeptides; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Molecular Structure; Neurons; Neuroprotective Agents; Organophosphorus Compounds	2006
N-acetylaspartate and N-acetylaspartylglutamate: neurobiology and clinical significance. Neurology, 2008, Apr-15, Volume: 70, Issue:16 Topics: Animals; Aspartic Acid; Biomarkers; Dipeptides; Humans; Nervous System Diseases; Neurobiology; Neuropeptides	2008

Trials

10 trial(s) available for isospaglumic acid and n-acetylaspartic acid

Article	Year
Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS. Magnetic resonance in medicine, 1998, Volume: 39, Issue:1 Topics: Adolescent; Adult; Aspartic Acid; Brain; Cerebellum; Cerebral Cortex; Choline; Dipeptides; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Protons; Reference Values; Sex Factors; Thalamus	1998
Central effects of acamprosate: part 2. Acamprosate modifies the brain in-vivo proton magnetic resonance spectrum in healthy young male volunteers. Psychiatry research, 1998, May-20, Volume: 82, Issue:2 Topics: Acamprosate; Adult; Alcohol Deterrents; Aspartic Acid; Brain; Creatine; Cross-Over Studies; Dipeptides; Double-Blind Method; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Taurine	1998
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter. Magnetic resonance in medicine, 2000, Volume: 44, Issue:3 Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Phantoms, Imaging; Regression Analysis; Sensitivity and Specificity	2000
Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy. Brain : a journal of neurology, 2001, Volume: 124, Issue:Pt 2 Topics: Adult; Analysis of Variance; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Male; Middle Aged; Nervous System Malformations; Phosphocreatine; Reference Values	2001
Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging. NMR in biomedicine, 2003, Volume: 16, Issue:1 Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oligodendroglioma; Reproducibility of Results; Sensitivity and Specificity	2003
Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease. Neurology, 2003, Mar-11, Volume: 60, Issue:5 Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Child; Child, Preschool; Choline; Creatinine; Dipeptides; Female; Follow-Up Studies; Humans; Infant; Inositol; Lactates; Leukodystrophy, Globoid Cell; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Parietal Lobe; Phosphocreatine	2003
Brainstem metabolites in multiple system atrophy of cerebellar type: 3.0-T magnetic resonance spectroscopy study. Movement disorders : official journal of the Movement Disorder Society, 2011, Volume: 26, Issue:7 Topics: Aged; Aspartic Acid; Biomarkers; Choline; Creatinine; Dipeptides; Feasibility Studies; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Medulla Oblongata; Middle Aged; Multiple System Atrophy; Pons; Protons; Severity of Illness Index	2011
Metabolic abnormalities in pain-processing regions of patients with fibromyalgia: a 3T MR spectroscopy study. AJNR. American journal of neuroradiology, 2011, Volume: 32, Issue:9 Topics: Adult; Aspartic Acid; Choline; Chronic Pain; Creatinine; Dipeptides; Female; Fibromyalgia; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Thalamus	2011
Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla. Biological psychiatry, 2012, Feb-01, Volume: 71, Issue:3 Topics: Adult; Aspartic Acid; Breath Tests; Cerebral Cortex; Dipeptides; Ethanol; Female; gamma-Aminobutyric Acid; Humans; Infusions, Intravenous; Magnetic Resonance Spectroscopy; Male	2012
Using NMR-Based Metabolomics to Evaluate Postprandial Urinary Responses Following Consumption of Minimally Processed Wheat Bran or Wheat Aleurone by Men and Women. Nutrients, 2016, Feb-17, Volume: 8, Issue:2 Topics: Adult; Alanine; Aspartic Acid; Betaine; Citric Acid; Diet; Dietary Fiber; Dipeptides; Female; Food Handling; Hippurates; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolomics; Postprandial Period; Seeds; Sex Factors; Triticum; Whole Grains; Young Adult	2016

Other Studies

128 other study(ies) available for isospaglumic acid and n-acetylaspartic acid

Article	Year
Developmental changes in beta-citryl-L-glutamate concentration and its synthetic and hydrolytic activities in neuronal cells cultured from chick embryo optic lobes. Journal of neurochemistry, 1992, Volume: 59, Issue:5 Topics: Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Dipeptides; Glutamates; Hydrolysis; Neurons; Optic Lobe, Nonmammalian	1992
On the N-acetyl methyl resonance in localized 1H NMR spectra of human brain in vivo. NMR in biomedicine, 1991, Volume: 4, Issue:4 Topics: Aspartic Acid; Brain Chemistry; Dipeptides; Humans; Magnetic Resonance Spectroscopy; Protons; Spectrum Analysis	1991
Reductions in acidic amino acids and N-acetylaspartylglutamate in amyotrophic lateral sclerosis CNS. Brain research, 1991, Aug-09, Volume: 556, Issue:1 Topics: Amino Acids; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Aspartic Acid; Cerebral Cortex; Dipeptides; Glutamates; Glutamic Acid; Humans; Motor Cortex; Reference Values; Spinal Cord	1991
Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies. Neuroscience, 1991, Volume: 45, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Aspartic Acid; Brain Chemistry; Cross Reactions; Dipeptides; Female; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Neurons; Rats; Rats, Inbred Strains; Spinal Cord	1991
Immunohistochemical localization of N-acetylaspartate in rat brain. Neuroreport, 1991, Volume: 2, Issue:3 Topics: Animals; Aspartic Acid; Brain; Brain Stem; Cerebral Cortex; Dipeptides; Hippocampus; Immunohistochemistry; Male; Rats; Tissue Distribution	1991
Automated precolumn fluorescence labelling by carbodiimide activation of N-acetylaspartate and N-acetylaspartylglutamate applied to an HPLC brain tissue analysis. Analytical biochemistry, 1991, Aug-01, Volume: 196, Issue:2 Topics: Animals; Anthracenes; Aspartic Acid; Brain; Brain Chemistry; Carbodiimides; Chromatography, High Pressure Liquid; Dicyclohexylcarbodiimide; Dipeptides; Fluorescent Dyes; Humans; Male; Rats; Rats, Inbred Strains	1991
Distribution of N-acetylaspartate, N-acetylaspartylglutamate, free glutamate and aspartate following complete mesencephalic transection in rat neuraxis. Neuroscience letters, 1990, Jun-22, Volume: 114, Issue:1 Topics: Animals; Aspartic Acid; Brain Chemistry; Brain Stem; Cerebellum; Dipeptides; Glutamates; Glutamic Acid; Male; Mesencephalon; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord	1990
Effects evoked by pentamethylenetetrazol-induced seizures upon N-acetylaspartate and N-acetylaspartylglutamate levels in different regions of the rat neuraxis. Life sciences, 1991, Volume: 48, Issue:23 Topics: Animals; Aspartic Acid; Brain; Brain Stem; Dipeptides; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Spinal Cord	1991
Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis. Annals of neurology, 1990, Volume: 28, Issue:1 Topics: Adult; Aged; Amino Acids; Amyotrophic Lateral Sclerosis; Aspartic Acid; Dipeptides; Female; Glutamates; Humans; Male; Middle Aged; Spinal Cord	1990
Acidic peptides in brain: do they act at putative glutamatergic synapses? Advances in experimental medicine and biology, 1986, Volume: 203 Topics: Animals; Aspartic Acid; Biological Transport; Brain; Brain Chemistry; Brain Mapping; Chlorides; Convulsants; Dipeptides; Glutamates; Hippocampus; Neurotransmitter Agents; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptosomes	1986
N-acetylaspartylglutamate identified in the rat retinal ganglion cells and their projections in the brain. Brain research, 1987, May-12, Volume: 411, Issue:1 Topics: Animals; Aspartic Acid; Axons; Chromatography, High Pressure Liquid; Dipeptides; Geniculate Bodies; Histocytochemistry; Immunoenzyme Techniques; Male; Rats; Rats, Inbred Strains; Retina; Retinal Ganglion Cells; Superior Colliculi; Visual Pathways	1987
Neurochemical and immunocytochemical studies on the distribution of N-acetyl-aspartylglutamate and N-acetyl-aspartate in rat spinal cord and some peripheral nervous tissues. Journal of neurochemistry, 1987, Volume: 48, Issue:3 Topics: Animals; Aspartic Acid; Dipeptides; Ganglia, Spinal; Ganglia, Sympathetic; Histocytochemistry; Immunoenzyme Techniques; Male; Motor Neurons; Peripheral Nerves; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Cord; Spinal Nerve Roots; Tissue Distribution	1987
Specific alterations in the levels of N-acetyl-aspartyl-glutamate in the nervous system of the dystrophic mouse. Neuroscience letters, 1987, Aug-18, Volume: 79, Issue:1-2 Topics: Animals; Aspartic Acid; Brain; Dipeptides; Male; Mice; Mice, Mutant Strains; Muscular Dystrophy, Animal; Spinal Cord	1987
Ontogenesis of N-acetyl-aspartate and N-acetyl-aspartyl-glutamate in rat brain. Brain research, 1984, Volume: 317, Issue:1 Topics: Age Factors; Animals; Aspartic Acid; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dipeptides; Female; Gestational Age; Rats; Rats, Inbred Strains	1984
N-acetyl-aspartyl-glutamate: regional levels in rat brain and the effects of brain lesions as determined by a new HPLC method. Journal of neurochemistry, 1984, Volume: 43, Issue:4 Topics: Animals; Aspartic Acid; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dipeptides; Hippocampus; Kainic Acid; Liver; Male; Myocardium; Rats; Rats, Inbred Strains; Spinal Cord; Tissue Distribution	1984
N-acetyl-L-aspartic acid, N-acetyl-alpha-L-aspartyl-L-glutamic acid and beta-citryl-L-glutamic acid in human urine. Clinica chimica acta; international journal of clinical chemistry, 1982, Mar-26, Volume: 120, Issue:1 Topics: Adult; Aged; Aspartic Acid; Chromatography, Gas; Dipeptides; Electrophoresis, Paper; Female; Glutamates; Humans; Male; Middle Aged; Reference Values	1982
A gas chromatographic method for the determination of N-acetyl-L-aspartic acid, N-acetyl-alpha-aspartylglutamic acid and beta-citryl-L-glutamic acid and their distributions in the brain and other organs of various species of animals. Journal of neurochemistry, 1981, Volume: 36, Issue:3 Topics: Aging; Animals; Aspartic Acid; Brain Chemistry; Carps; Chickens; Chromatography, Gas; Citrates; Columbidae; Dipeptides; Glutamates; Guinea Pigs; Male; Nervous System; Rabbits; Ranidae; Rats; Species Specificity; Turtles	1981
Developmental changes of N-acetyl-L-aspartic acid, N-acetyl-alpha-aspartylglutamic acid and beta-citryl-L-glutamic acid in different brain regions and spinal cords of rat and guinea pig. Journal of neurochemistry, 1981, Volume: 37, Issue:4 Topics: Aging; Animals; Aspartic Acid; Brain; Dipeptides; Glutamates; Guinea Pigs; Organ Specificity; Rats; Rats, Inbred Strains; Species Specificity; Spinal Cord	1981
Differential distribution of N-acetylaspartylglutamate and N-acetylaspartate immunoreactivities in rat forebrain. Journal of neurocytology, 1995, Volume: 24, Issue:6 Topics: Amygdala; Animals; Antibody Specificity; Aspartic Acid; Carbodiimides; Cross Reactions; Dipeptides; Extrapyramidal Tracts; Hippocampus; Histamine H1 Antagonists; Hypothalamus; Immunohistochemistry; Male; Motor Cortex; Neuropeptides; Olfactory Pathways; Prosencephalon; Pyramidal Cells; Rats; Rats, Inbred Strains; Somatosensory Cortex; Thalamus	1995
Relative concentrations of proton MR visible neurochemicals in gray and white matter in human brain. Magnetic resonance in medicine, 1995, Volume: 33, Issue:6 Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Dipeptides; Female; Humans; Magnetic Resonance Spectroscopy; Male; Neuropeptides; Phosphocreatine	1995
N-acetylaspartate and N-acetylaspartylglutamate levels in Alzheimer's disease post-mortem brain tissue. Journal of the neurological sciences, 1994, Dec-20, Volume: 127, Issue:2 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amygdala; Aspartic Acid; Brain Chemistry; Cerebellar Cortex; Chromatography, High Pressure Liquid; Dipeptides; Female; Hippocampus; Histamine H1 Antagonists; Humans; Male; Middle Aged; Olfactory Bulb; Spectrometry, Fluorescence	1994
Methylphenidate increases rat cerebral cortex levels of N-acetyl-aspartic acid and N-acetyl-aspartyl-glutamic acid. Biological psychiatry, 1994, Nov-01, Volume: 36, Issue:9 Topics: Animals; Aspartic Acid; Cerebral Cortex; Chromatography, High Pressure Liquid; Dipeptides; Male; Methylphenidate; Rats; Rats, Sprague-Dawley	1994
N-acetylaspartylglutamate selectively inhibits neuronal responses to N-methyl-D-aspartic acid in vitro. Journal of neurochemistry, 1994, Volume: 63, Issue:3 Topics: Animals; Aspartic Acid; Canavan Disease; Cell Survival; Cells, Cultured; Cerebellum; Culture Media; Dipeptides; Kainic Acid; Mice; Mice, Inbred BALB C; N-Methylaspartate; Neurons	1994
Enhanced carbodiimide fixation for immunohistochemistry: application to the comparative distributions of N-acetylaspartylglutamate and N-acetylaspartate immunoreactivities in rat brain. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1993, Volume: 41, Issue:4 Topics: Animals; Aspartic Acid; Axons; Brain Chemistry; Dendrites; Dimethyl Sulfoxide; Dipeptides; Ethyldimethylaminopropyl Carbodiimide; Glutaral; Hydrogen-Ion Concentration; Immunohistochemistry; Rats; Serum Albumin, Bovine; Spinal Cord; Succinimides; Temperature; Tissue Fixation	1993
Absolute concentrations of metabolites in the adult human brain in vivo: quantification of localized proton MR spectra. Radiology, 1993, Volume: 187, Issue:1 Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Dipeptides; Humans; Inositol; Magnetic Resonance Spectroscopy; Phosphocreatine	1993
Altered metabolism of excitatory amino acids, N-acetyl-aspartate and N-acetyl-aspartyl-glutamate in amyotrophic lateral sclerosis. Brain research bulletin, 1993, Volume: 30, Issue:3-4 Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Brain; Dipeptides; Humans; Middle Aged; Spinal Cord	1993
N-acetyl-L-aspartate and acetate 1H NMR signal overlapping under mild acidic pH conditions. Magnetic resonance in medicine, 1993, Volume: 29, Issue:5 Topics: Acetates; Acetoacetates; Aspartic Acid; Dipeptides; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy	1993
In vivo microdialysis and gas chromatography/mass spectrometry for studies on release of N-acetylaspartlyglutamate and N-acetylaspartate in rat brain hypothalamus. Journal of neuroscience methods, 1995, Volume: 62, Issue:1-2 Topics: Animals; Aspartic Acid; Brain Chemistry; Dipeptides; Gas Chromatography-Mass Spectrometry; Histamine H1 Antagonists; Hypothalamus; Membrane Potentials; Microdialysis; Potassium Chloride; Rats	1995
Regional and developmental variations in metabolite concentration in the rat brain and eye: a study using 1H NMR spectroscopy and high performance liquid chromatography. Neurochemical research, 1996, Volume: 21, Issue:9 Topics: Aging; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Callosum; Dipeptides; Eye; gamma-Aminobutyric Acid; Glutamic Acid; Hydrogen; Magnetic Resonance Spectroscopy; Olfactory Bulb; Oligodendroglia; Optic Nerve; Organ Specificity; Rats; Stem Cells	1996
Temporal changes in proton MRS metabolites after kainic acid-induced seizures in rat brain. Epilepsia, 1997, Volume: 38, Issue:1 Topics: Animals; Aspartic Acid; Brain; Cell Count; Choline; Creatinine; Dipeptides; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Neuropeptides; Protons; Rats; Rats, Sprague-Dawley; Seizures; Temporal Lobe	1997
Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS. NMR in biomedicine, 1997, Volume: 10, Issue:2 Topics: Adolescent; Adult; Aspartic Acid; Brain; Dipeptides; Feasibility Studies; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Protons; Tissue Distribution	1997
Mast cells contain large quantities of secretagogue-sensitive N-acetylaspartate. Journal of neurochemistry, 1997, Volume: 69, Issue:3 Topics: Animals; Aspartic Acid; Cytoplasmic Granules; Dipeptides; Histamine; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Male; Mast Cells; Neurons; p-Methoxy-N-methylphenethylamine; Peptides; Peritoneal Cavity; Rats; Rats, Wistar; Wasp Venoms	1997
N-acetylaspartylglutamate, N-acetylaspartate, and N-acetylated alpha-linked acidic dipeptidase in human brain and their alterations in Huntington and Alzheimer's diseases. Molecular and chemical neuropathology, 1997, Volume: 31, Issue:2 Topics: Alzheimer Disease; Amino Acids; Antigens, Surface; Aspartic Acid; Brain; Case-Control Studies; Cell Count; Dipeptidases; Dipeptides; Glutamate Carboxypeptidase II; Humans; Huntington Disease; Neurons; Neuropeptides; Reference Values	1997
Labeling of N-acetylaspartate and N-acetylaspartylglutamate in rat neocortex, hippocampus and cerebellum from [1-13C]glucose. Neuroscience letters, 1998, Jul-31, Volume: 251, Issue:3 Topics: Animals; Aspartic Acid; Brain; Carbon Isotopes; Cerebellum; Dipeptides; Glucose; Hippocampus; Male; Neocortex; Neuropeptides; Nuclear Magnetic Resonance, Biomolecular; Rats; Rats, Sprague-Dawley	1998
Markers of glutamatergic neurotransmission and oxidative stress associated with tardive dyskinesia. The American journal of psychiatry, 1998, Volume: 155, Issue:9 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Biomarkers; Corpus Striatum; Dipeptides; Dopamine Antagonists; Dyskinesia, Drug-Induced; Female; Glutamates; Humans; Lipid Peroxides; Male; Middle Aged; Neuropeptides; Oxidative Stress; Psychiatric Status Rating Scales; Receptors, Dopamine; Schizophrenia; Superoxide Dismutase; Synaptic Transmission	1998
N-acetylaspartic acid (NAA) and N-acetylaspartylglutamic acid (NAAG) in human ventricular, subarachnoid, and lumbar cerebrospinal fluid. Neurochemical research, 1999, Volume: 24, Issue:10 Topics: Adult; Aspartic Acid; Cerebral Ventricles; Chromatography, High Pressure Liquid; Dipeptides; Gas Chromatography-Mass Spectrometry; Humans; Lumbar Vertebrae; Male; Middle Aged; Spectrophotometry, Ultraviolet; Subarachnoid Space	1999
Simultaneous determination of N-acetylaspartic acid, N-acetylglutamic acid, and N-acetylaspartylglutamic acid in whole brain of 3-mercaptopropionic acid-treated rats using liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. Analytical biochemistry, 1999, Dec-15, Volume: 276, Issue:2 Topics: 3-Mercaptopropionic Acid; Animals; Aspartic Acid; Atmospheric Pressure; Brain; Brain Chemistry; Chromatography, Liquid; Dipeptides; Enzyme Inhibitors; Glutamate Decarboxylase; Glutamates; Male; Mass Spectrometry; Rats; Rats, Wistar	1999
1H magnetic resonance spectroscopy of normal appearing white matter in primary progressive multiple sclerosis. Journal of neurology, 1999, Volume: 246, Issue:11 Topics: Adult; Aspartic Acid; Brain; Cohort Studies; Creatine; Dipeptides; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Multiple Sclerosis, Chronic Progressive; Protons; Reference Values	1999
Magnetization transfer attenuation of creatine resonances in localized proton MRS of human brain in vivo. NMR in biomedicine, 1999, Volume: 12, Issue:8 Topics: Adult; Aspartic Acid; Brain; Creatine; Dipeptides; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Magnetics; Male	1999
In vitro high resolution proton magnetic resonance study of human cerebellar development during the period from the fetus to childhood. Physiological chemistry and physics and medical NMR, 1999, Volume: 31, Issue:2 Topics: Aging; Amino Acids; Aspartic Acid; Cerebellum; Child; Child, Preschool; Creatinine; Dipeptides; Embryonic and Fetal Development; Fetus; Humans; Infant; Magnetic Resonance Spectroscopy	1999
Measurement of neurotransmitter metabolites in the cerebrospinal fluid of phenylketonuric patients under dietary treatment. Journal of inherited metabolic disease, 2000, Volume: 23, Issue:4 Topics: Adolescent; Adult; Aspartic Acid; Child; Dipeptides; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Magnetic Resonance Imaging; Male; Phenylketonurias; Radiography; Serotonin	2000
Absence of N-acetylaspartate in the human brain: impact on neurospectroscopy? Annals of neurology, 2001, Volume: 49, Issue:4 Topics: Aspartic Acid; Brain; Child, Preschool; Dipeptides; Humans; Magnetic Resonance Spectroscopy; Male; Nervous System Diseases	2001
In vivo short echo time 1H-magnetic resonance spectroscopic imaging (MRSI) of the temporal lobes. NeuroImage, 2001, Volume: 14, Issue:2 Topics: Adult; Aspartic Acid; Brain Mapping; Choline; Creatine; Dipeptides; Dominance, Cerebral; Energy Metabolism; Female; Fourier Analysis; Hippocampus; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Reference Values; Temporal Lobe	2001
Postmortem degradation of N-acetyl aspartate and N-acetyl aspartylglutamate: an HPLC analysis of different rat CNS regions. Neurochemical research, 2001, Volume: 26, Issue:6 Topics: Animals; Aspartic Acid; Central Nervous System; Chromatography, High Pressure Liquid; Dipeptides; Hydrolysis; Male; Postmortem Changes; Rats; Rats, Sprague-Dawley; Tissue Distribution	2001
N-acetylaspartylglutamate (NAAG) is the probable mediator of axon-to-glia signaling in the crayfish medial giant nerve fiber. Neuroscience, 2001, Volume: 106, Issue:1 Topics: Animals; Aspartic Acid; Astacoidea; Axons; Carboxypeptidases; Cell Communication; Cysteic Acid; Dipeptides; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamate Carboxypeptidase II; Glutamic Acid; Membrane Potentials; N-Methylaspartate; Nervous System; Neuroglia; Organophosphorus Compounds; Receptors, Glutamate; Signal Transduction; Time Factors	2001
N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerve. Annals of neurology, 2002, Volume: 51, Issue:1 Topics: Age Factors; Animals; Aspartic Acid; Axons; Biomarkers; Cell Division; Dipeptides; Immunohistochemistry; Male; Myelin Proteins; Nerve Degeneration; Oligodendroglia; Optic Nerve; Optic Nerve Injuries; Rats; Rats, Sprague-Dawley; Stem Cells	2002
Maturation of the human fetal brain as observed by 1H MR spectroscopy. Magnetic resonance in medicine, 2002, Volume: 48, Issue:4 Topics: Aspartic Acid; Brain; Choline; Creatine; Dipeptides; Female; Fetus; Gestational Age; Humans; Inositol; Magnetic Resonance Spectroscopy; Pregnancy	2002
N-acetylaspartate and N-Acetylaspartylglutamate deficits in superior temporal cortex in schizophrenia and bipolar disorder: a postmortem study. Biological psychiatry, 2003, Jun-15, Volume: 53, Issue:12 Topics: Aspartic Acid; Autopsy; Biomarkers; Bipolar Disorder; Case-Control Studies; Chromatography, High Pressure Liquid; Depressive Disorder; Dipeptides; Frontal Lobe; Humans; Schizophrenia; Temporal Lobe	2003
Morphology and ultrastructure of rat hippocampal formation after i.c.v. administration of N-acetyl-L-aspartyl-L-glutamate. Neuroscience, 2003, Volume: 122, Issue:1 Topics: Animals; Aspartic Acid; Cell Count; Cell Death; Dipeptides; DNA Fragmentation; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; In Situ Nick-End Labeling; Injections, Intraventricular; Male; Microscopy, Electron; Nerve Degeneration; Neurons; Neuropeptides; Neurotoxins; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors	2003
Measurement of brain glutamate using TE-averaged PRESS at 3T. Magnetic resonance in medicine, 2004, Volume: 51, Issue:3 Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Dipeptides; Female; Fourier Analysis; Glutamic Acid; Glutamine; Humans; Image Enhancement; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropeptides; Reproducibility of Results	2004
A comparative study of myo-inositol quantification using LCmodel at 1.5 T and 3.0 T with 3 D 1H proton spectroscopic imaging of the human brain. Magnetic resonance imaging, 2004, Volume: 22, Issue:4 Topics: Aspartic Acid; Brain; Dipeptides; Female; Humans; Hydrogen; Inositol; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging; Protons; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted	2004
Biosynthesis of NAAG by an enzyme-mediated process in rat central nervous system neurons and glia. Journal of neurochemistry, 2004, Volume: 90, Issue:4 Topics: Animals; Aspartic Acid; Cells, Cultured; Central Nervous System; Cerebellum; Cerebral Cortex; Culture Media, Serum-Free; Dipeptides; Enzymes; Glutamic Acid; Glutamine; Neuroglia; Neurons; Potassium Chloride; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Spinal Cord; Tritium	2004
Clinical correlation of brain MRI and MRS abnormalities in patients with Wilson disease. Neurology, 2004, Aug-24, Volume: 63, Issue:4 Topics: Adult; Aged; Aspartic Acid; Atrophy; Brain; Brain Chemistry; Chelation Therapy; Copper; Dipeptides; Female; Hepatolenticular Degeneration; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Mitochondria; Nervous System Diseases; Penicillamine; Severity of Illness Index; Single-Blind Method; Trientine	2004
Chronic phencyclidine administration induces schizophrenia-like changes in N-acetylaspartate and N-acetylaspartylglutamate in rat brain. Schizophrenia research, 2005, Mar-01, Volume: 73, Issue:2-3 Topics: Animals; Aspartic Acid; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Frontal Lobe; Hallucinogens; Hippocampus; Male; Phencyclidine; Psychotic Disorders; Rats; Rats, Long-Evans; Temporal Lobe	2005
High-field localized 1H NMR spectroscopy in the anesthetized and in the awake monkey. Magnetic resonance imaging, 2004, Volume: 22, Issue:10 Topics: Anesthesia, General; Animals; Artifacts; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Dipeptides; Glutamic Acid; Glutamine; Glutathione; Hydrogen; Image Enhancement; Inositol; Lactic Acid; Macaca mulatta; Magnetic Resonance Spectroscopy; Phosphocreatine; Stereoisomerism; Taurine; Wakefulness	2004
In vivo quantitative 1H MRS of cerebellum and evaluation of quantitation reproducibility by simulation of different levels of noise and spectral resolution. Magnetic resonance imaging, 2004, Volume: 22, Issue:10 Topics: Adult; Artifacts; Aspartic Acid; Body Water; Cerebellum; Choline; Creatine; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Hydrogen; Image Enhancement; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Neuropeptides	2004
Quantitative proton MRS of Pelizaeus-Merzbacher disease: evidence of dys- and hypomyelination. Neurology, 2005, Sep-13, Volume: 65, Issue:5 Topics: Aspartic Acid; Basal Ganglia; Brain; Cerebral Cortex; Child; Child, Preschool; Choline; Creatine; Dipeptides; Down-Regulation; Glutamine; Humans; Infant; Inositol; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Pelizaeus-Merzbacher Disease; Phosphocreatine; Predictive Value of Tests; Protons; Up-Regulation	2005
Magnetic resonance imaging and proton magnetic resonance spectroscopy of megalencephaly and dilated Virchow-Robin spaces. Pediatric neurology, 2006, Volume: 34, Issue:1 Topics: Aspartic Acid; Brain Diseases; Child; Child, Preschool; Choline; Creatine; Dilatation, Pathologic; Dipeptides; Female; Humans; Infant; Infant, Newborn; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Organ Size; Phosphocreatine	2006
Expression of N-acetylaspartate and N-acetylaspartylglutamate in the nervous system. Advances in experimental medicine and biology, 2006, Volume: 576 Topics: Animals; Aspartic Acid; Brain; Dipeptides; Glutamate Decarboxylase; Immunohistochemistry; Isoenzymes; Macaca mulatta; Neurons; Neurotransmitter Agents; Phylogeny; Rats	2006
Hypoacetylaspartia: clinical and biochemical follow-up of a patient. Advances in experimental medicine and biology, 2006, Volume: 576 Topics: Aspartic Acid; Child, Preschool; Dipeptides; Follow-Up Studies; Humans; Magnetic Resonance Spectroscopy; Male; Nervous System Diseases	2006
Synthesis of N-acetylaspartyl-glutamate (NAAG) and N-acetylaspartate (NAA) in axons and glia of the crayfish medial giant nerve fiber. Advances in experimental medicine and biology, 2006, Volume: 576 Topics: Animals; Aspartic Acid; Astacoidea; Axons; Dipeptides; Glutamic Acid; Nerve Fibers; Neuroglia	2006
Regulation of N-acetylaspartate and N-acetylaspartylglutamate biosynthesis by protein kinase activators. Journal of neurochemistry, 2006, Volume: 98, Issue:6 Topics: Aspartic Acid; Bucladesine; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Dipeptides; Dose-Response Relationship, Drug; Enzyme Activation; Glutamine; Humans; Neuroblastoma; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Time Factors	2006
Quantitative proton MRS of cerebral metabolites in laminin alpha2 chain deficiency. Brain & development, 2007, Volume: 29, Issue:6 Topics: Adolescent; Aspartic Acid; Cerebral Cortex; Child; Child, Preschool; Creatine; Dipeptides; Humans; Infant; Laminin; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Muscular Dystrophies; Phosphocreatine; Protons	2007
Natural history of Canavan disease revealed by proton magnetic resonance spectroscopy (1H-MRS) and diffusion-weighted MRI. Neuropediatrics, 2006, Volume: 37, Issue:4 Topics: Age Factors; Aspartic Acid; Atrophy; Brain; Canavan Disease; Case-Control Studies; Child, Preschool; Confidence Intervals; Diffusion Magnetic Resonance Imaging; Dipeptides; Female; Humans; Infant; Magnetic Resonance Spectroscopy; Male; Protons; Reference Values	2006
Carbamazepine treatment recovered low N-acetylaspartate+N-acetylaspartylglutamate (tNAA) levels in the megencephaly mouse BALB/cByJ-Kv1.1(mceph/mceph). Neurobiology of disease, 2007, Volume: 26, Issue:1 Topics: Amino Acids; Anesthesia; Animals; Aspartic Acid; Brain; Carbamazepine; Choline; Data Interpretation, Statistical; Dipeptides; Female; Kv1.1 Potassium Channel; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Sex Characteristics	2007
1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG. Epilepsia, 2007, Volume: 48, Issue:2 Topics: Adult; Aspartic Acid; Biomarkers; Brain Mapping; Choline; Creatine; Dipeptides; Electroencephalography; Epilepsy, Temporal Lobe; Female; Functional Laterality; Glutamine; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Monitoring, Physiologic; Seizures; Severity of Illness Index; Temporal Lobe; Videotape Recording	2007
In vivo differentiation of N-acetyl aspartyl glutamate from N-acetyl aspartate at 3 Tesla. Magnetic resonance in medicine, 2007, Volume: 57, Issue:6 Topics: Adult; Artifacts; Aspartic Acid; Brain Chemistry; Dipeptides; Female; Humans; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging	2007
Long and short echo time proton magnetic resonance spectroscopic imaging of the healthy aging brain. Journal of magnetic resonance imaging : JMRI, 2007, Volume: 26, Issue:6 Topics: Aged; Aged, 80 and over; Aging; Artifacts; Aspartic Acid; Brain; Choline; Creatine; Dipeptides; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons	2007
Oxidative stress and protein oxidation in the brain of water drinking and alcohol drinking rats administered the HIV envelope protein, gp120. Journal of neurochemistry, 2008, Volume: 104, Issue:6 Topics: Acetaldehyde; Alcohol Drinking; Animals; Aspartic Acid; Brain; Central Nervous System Depressants; Dipeptides; Drinking; Ethanol; Free Radicals; HIV Envelope Protein gp120; Isotonic Solutions; Male; Oxidation-Reduction; Oxidative Stress; Peroxiredoxins; Phosphatidylethanolamine Binding Protein; Proteins; Rats; Sodium Chloride; Sulfhydryl Compounds	2008
Regional apparent metabolite concentrations in young adult brain measured by (1)H MR spectroscopy at 3 Tesla. Journal of magnetic resonance imaging : JMRI, 2008, Volume: 27, Issue:3 Topics: Adult; Age Factors; Aspartic Acid; Brain Chemistry; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male	2008
Cognitive impairment in multiple sclerosis can be predicted by imaging early in the disease. Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:8 Topics: Adolescent; Adult; Aspartic Acid; Atrophy; Brain; Cerebral Ventricles; Cognition Disorders; Cohort Studies; Dipeptides; Disability Evaluation; Female; Follow-Up Studies; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Neurologic Examination; Neuropsychological Tests; Predictive Value of Tests; Prospective Studies	2008
Reduced parietooccipital white matter glutamine measured by proton magnetic resonance spectroscopy in treated graves' disease patients. The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8 Topics: Adult; Aspartic Acid; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Graves Disease; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Parietal Lobe; Prospective Studies	2008
The effect of epileptic seizures on proton MRS visible neurochemical concentrations. Epilepsy research, 2008, Volume: 81, Issue:1 Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Data Interpretation, Statistical; Dipeptides; Female; Glutamic Acid; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Protons; Seizures	2008
Proton magnetic resonance spectroscopy reveals medial temporal metabolic abnormalities in adolescents with history of preterm birth. Pediatric research, 2008, Volume: 64, Issue:5 Topics: Adolescent; Aspartic Acid; Case-Control Studies; Creatine; Dipeptides; Female; Gestational Age; Hippocampus; Humans; Infant, Newborn; Infant, Premature; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Organ Size; Protons; Temporal Lobe	2008
Antipsychotic drugs increase N-acetylaspartate and N-acetylaspartylglutamate in SH-SY5Y human neuroblastoma cells. Journal of neurochemistry, 2008, Volume: 106, Issue:4 Topics: Antipsychotic Agents; Aspartic Acid; Cell Line, Tumor; Clozapine; Dipeptides; Dose-Response Relationship, Drug; Haloperidol; Humans; Neuroblastoma; Neurons	2008
Simultaneous determination of N-acetylaspartylglutamate and N-acetylaspartate in rat brain homogenate using high-performance liquid chromatography with pre-column fluorescence derivatization. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Nov-15, Volume: 875, Issue:2 Topics: Animals; Aspartic Acid; Brain Chemistry; Cerebrum; Chromatography, High Pressure Liquid; Dipeptides; Fluorescent Dyes; Hippocampus; Ketamine; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity	2008
Distinct MRI pattern in lesional and perilesional area after traumatic brain injury in rat--11 months follow-up. Experimental neurology, 2009, Volume: 215, Issue:1 Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Injuries; Creatine; Diffusion Magnetic Resonance Imaging; Dipeptides; Disease Models, Animal; Follow-Up Studies; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Statistics, Nonparametric; Time Factors	2009
Development and application of a liquid chromatography/tandem mass spectrometric assay for measurement of N-acetylaspartate, N-acetylaspartylglutamate and glutamate in brain slice superfusates and tissue extracts. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Dec-15, Volume: 876, Issue:2 Topics: Animals; Aspartic Acid; Brain Chemistry; Chromatography, High Pressure Liquid; Dipeptides; Glutamic Acid; Rats; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry	2008
Intracerebroventricular administration of N-acetylaspartic acid impairs antioxidant defenses and promotes protein oxidation in cerebral cortex of rats. Metabolic brain disease, 2009, Volume: 24, Issue:2 Topics: Animals; Antioxidants; Aspartic Acid; Brain Damage, Chronic; Canavan Disease; Catalase; Cerebral Cortex; Dipeptides; Disease Models, Animal; Glucosephosphate Dehydrogenase; Glutathione Peroxidase; Injections, Intraventricular; Lipid Peroxidation; Male; Neuropeptides; Neurotoxins; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar	2009
Are astrocytes the missing link between lack of brain aspartoacylase activity and the spongiform leukodystrophy in Canavan disease? Neurochemical research, 2009, Volume: 34, Issue:9 Topics: Amidohydrolases; Animals; Aspartic Acid; Astrocytes; Brain; Canavan Disease; Dipeptides; Disease Models, Animal; Extracellular Fluid; Humans; Myelin Sheath	2009
The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes. Brain : a journal of neurology, 2009, Volume: 132, Issue:Pt 6 Topics: Action Potentials; Animals; Aspartic Acid; Calcium; Canavan Disease; Cerebellum; Dipeptides; Evoked Potentials; Glutamic Acid; Hydrolysis; Oligodendroglia; Patch-Clamp Techniques; Pelizaeus-Merzbacher Disease; Rats; Receptors, N-Methyl-D-Aspartate; Tissue Culture Techniques	2009
MR spectroscopic evaluation of N-acetylaspartate's T2 relaxation time and concentration corroborates white matter abnormalities in schizophrenia. NeuroImage, 2009, Nov-15, Volume: 48, Issue:3 Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Dipeptides; Female; Frontal Lobe; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Phosphocreatine; Protons; Schizophrenia; Water	2009
Riluzole decreases synthesis of N-acetylaspartate and N-acetylaspartylglutamate in SH-SY5Y human neuroblastoma cells. Brain research, 2010, Jun-02, Volume: 1334 Topics: Aspartic Acid; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Riluzole; Time Factors	2010
Differential regional N-acetylaspartate deficits in postmortem brain in schizophrenia, bipolar disorder and major depressive disorder. Journal of psychiatric research, 2011, Volume: 45, Issue:1 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Depressive Disorder, Major; Dipeptides; Female; Humans; Male; Middle Aged; Schizophrenia	2011
Proton magnetic resonance spectroscopy of brain in obstructive sleep apnoea in north Indian Asian subjects. The Indian journal of medical research, 2010, Volume: 132 Topics: Adult; Analysis of Variance; Anthropometry; Aspartic Acid; Brain; Dipeptides; Female; Humans; India; Magnetic Resonance Spectroscopy; Male; Middle Aged; Polysomnography; Sleep Apnea, Obstructive	2010
Evidence for neuroinflammation and neuroprotection in HCV infection-associated encephalopathy. Gut, 2011, Volume: 60, Issue:3 Topics: Adult; Aged; Aspartic Acid; Brain; Brain Mapping; Case-Control Studies; Choline; Cognition Disorders; Creatine; Dipeptides; Fatigue; Female; Hepatic Encephalopathy; Hepatitis C; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Psychometrics; Severity of Illness Index	2011
Transcranial direct current stimulation (tDCS) produces localized and specific alterations in neurochemistry: a ¹H magnetic resonance spectroscopy study. Neuroscience letters, 2011, Aug-01, Volume: 500, Issue:1 Topics: Adult; Aspartic Acid; Brain; Cerebrum; Dipeptides; Electric Stimulation; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Young Adult	2011
Proton magnetic resonance spectroscopy and thought disorder in childhood schizophrenia. Schizophrenia research, 2011, Volume: 133, Issue:1-3 Topics: Adolescent; Analysis of Variance; Aspartic Acid; Brain; Child; Choline; Cognition Disorders; Creatine; Dipeptides; Female; Humans; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Phosphocreatine; Protons; Psychiatric Status Rating Scales; Schizophrenia, Childhood; Statistics, Nonparametric	2011
N-acetylaspartylglutamate (NAAG) and N-acetylaspartate (NAA) in patients with schizophrenia. Schizophrenia bulletin, 2013, Volume: 39, Issue:1 Topics: Adult; Aspartic Acid; Dipeptides; Female; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Prefrontal Cortex; Protons; Psychiatric Status Rating Scales; Schizophrenia	2013
Metabolite detection of pancreatic carcinoma by in vivo proton MR spectroscopy at 3T: initial results. La Radiologia medica, 2012, Volume: 117, Issue:5 Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Choline; Dipeptides; Fatty Acids, Unsaturated; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pancreatic Neoplasms; Software	2012
Glutamate carboxypeptidase II gene polymorphisms and neural tube defects in a high-risk Chinese population. Metabolic brain disease, 2012, Volume: 27, Issue:1 Topics: Adult; Anencephaly; Asian People; Aspartic Acid; Case-Control Studies; China; Dipeptides; Encephalocele; Female; Folic Acid; Gene Frequency; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Neural Tube Defects; Polymorphism, Genetic; Risk Factors; Spinal Dysraphism; Young Adult	2012
Increased N-acetylaspartate in model mouse of Pelizaeus-Merzbacher disease. Journal of magnetic resonance imaging : JMRI, 2012, Volume: 35, Issue:2 Topics: Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Dipeptides; Disease Models, Animal; Immunoenzyme Techniques; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mice; Pelizaeus-Merzbacher Disease; Thalamus	2012
Altered development of the dorsolateral prefrontal cortex in chromosome 22q11.2 deletion syndrome: an in vivo proton spectroscopy study. Biological psychiatry, 2012, Oct-15, Volume: 72, Issue:8 Topics: Adolescent; Age Factors; Aspartic Acid; Chi-Square Distribution; Child; Cross-Sectional Studies; DiGeorge Syndrome; Dipeptides; Female; Humans; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Prefrontal Cortex; Protons	2012
NAA and NAAG variation in neuronal activation during visual stimulation. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2012, Volume: 45, Issue:11 Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Dipeptides; Female; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Photic Stimulation; Young Adult	2012
Iron supplementation dose for perinatal iron deficiency differentially alters the neurochemistry of the frontal cortex and hippocampus in adult rats. Pediatric research, 2013, Volume: 73, Issue:1 Topics: Anemia, Iron-Deficiency; Animals; Aspartic Acid; Cognition Disorders; Dietary Supplements; Dipeptides; Ethanolamines; Frontal Lobe; Hippocampus; Iron; Magnetic Resonance Spectroscopy; Phosphorylcholine; Rats	2013
Longitudinal 1H MRS of rat forebrain from infancy to adulthood reveals adolescence as a distinctive phase of neurometabolite development. NMR in biomedicine, 2013, Volume: 26, Issue:6 Topics: Aging; Animals; Aspartic Acid; Dipeptides; Glutamic Acid; Inositol; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Prosencephalon; Rats; Rats, Sprague-Dawley; Taurine	2013
Decreased frontal N-acetylaspartate levels in adolescents concurrently using both methamphetamine and marijuana. Behavioural brain research, 2013, Jun-01, Volume: 246 Topics: Adolescent; Amphetamine-Related Disorders; Analysis of Variance; Aspartic Acid; Brain Mapping; Dipeptides; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Marijuana Smoking; Protons; Regression Analysis	2013
Brain metabolite concentrations are associated with illness severity scores and white matter abnormalities in very preterm infants. Pediatric research, 2013, Volume: 74, Issue:1 Topics: Aspartic Acid; Brain; Dipeptides; Humans; Infant, Newborn; Infant, Premature; Severity of Illness Index	2013
Do reductions in brain N-acetylaspartate levels contribute to the etiology of some neuropsychiatric disorders? Journal of neuroscience research, 2013, Volume: 91, Issue:7 Topics: Acetyltransferases; Analysis of Variance; Animals; Aspartic Acid; Brain; Choline; Chromatography, High Pressure Liquid; Dipeptides; Dopamine Agents; Exploratory Behavior; Gene Expression Regulation; Locomotion; Magnetic Resonance Spectroscopy; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout	2013
N-acetylaspartate (NAA) and N-acetylaspartylglutamate (NAAG) promote growth and inhibit differentiation of glioma stem-like cells. The Journal of biological chemistry, 2013, Sep-06, Volume: 288, Issue:36 Topics: Amidohydrolases; Animals; Aspartic Acid; Cell Differentiation; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Dipeptides; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Proteins; Neoplastic Stem Cells; Neuroprotective Agents; Oligodendroglioma	2013
Thalamic metabolic abnormalities in patients with Huntington's disease measured by magnetic resonance spectroscopy. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2013, Volume: 46, Issue:8 Topics: Adolescent; Adult; Aged; Aspartic Acid; Case-Control Studies; Creatine; Deuterium; Dipeptides; Female; Glycerylphosphorylcholine; Humans; Huntington Disease; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Activity; Phosphocreatine; Phosphorylcholine; Thalamic Diseases; Thalamus; Trinucleotide Repeats; Young Adult	2013
γ-Aminobutyric acid (GABA) concentration inversely correlates with basal perfusion in human occipital lobe. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:3 Topics: Adult; Aspartic Acid; Blood Volume; Cerebrovascular Circulation; Dipeptides; gamma-Aminobutyric Acid; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Occipital Lobe; Spin Labels; Young Adult	2014
Overexpression of Shati/Nat8l, an N-acetyltransferase, in the nucleus accumbens attenuates the response to methamphetamine via activation of group II mGluRs in mice. The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:8 Topics: Acetyltransferases; Amino Acids; Animals; Aspartic Acid; Conditioning, Psychological; Corpus Striatum; Dipeptides; Dopamine; Male; Methamphetamine; Mice; Mice, Transgenic; Motor Activity; Nucleus Accumbens; Receptors, Metabotropic Glutamate; Xanthenes	2014
Evaluation of impact-induced traumatic brain injury in the Göttingen Minipig using two input modes. Traffic injury prevention, 2014, Volume: 15 Suppl 1 Topics: Animals; Aspartic Acid; Brain Injuries; Dipeptides; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Swine; Swine, Miniature	2014
N-acetylaspartate normalization in bipolar depression after lamotrigine treatment. Bipolar disorders, 2015, Volume: 17, Issue:4 Topics: Adult; Aged; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Dipeptides; Female; Gyrus Cinguli; Humans; Lamotrigine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values; Triazines	2015
(1)H-magnetic resonance spectroscopy in social anxiety disorder. Progress in neuro-psychopharmacology & biological psychiatry, 2015, Apr-03, Volume: 58 Topics: Adult; Anxiety Disorders; Aspartic Acid; Creatine; Dipeptides; Female; Gyrus Cinguli; Humans; Male; Neostriatum; Phosphorylcholine; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Social Perception; Thalamus	2015
Effects of a high-caloric diet and physical exercise on brain metabolite levels: a combined proton MRS and histologic study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2015, Mar-31, Volume: 35, Issue:4 Topics: Animals; Aspartic Acid; Brain; Carbohydrate Metabolism; Diet; Dipeptides; Energy Intake; Fatty Acids; Glucose; Glutamic Acid; Hyperglycemia; Insulin; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Obesity; Physical Conditioning, Animal; Protons; Running	2015
Neuronal marker recovery after Simvastatin treatment in dementia in the rat brain: in vivo magnetic resonance study. Behavioural brain research, 2015, May-01, Volume: 284 Topics: Animals; Aspartic Acid; Biomarkers; Brain; Dementia; Dipeptides; Disease Models, Animal; Galactose; Inositol; Magnetic Resonance Spectroscopy; Male; Nootropic Agents; Organ Size; Phosphorus Isotopes; Protons; Rats, Wistar; Simvastatin; Spatial Learning; Spatial Memory; Thiobarbituric Acid Reactive Substances; Treatment Outcome; Ubiquinone	2015
Cuprizone-induced demyelination and demyelination-associated inflammation result in different proton magnetic resonance metabolite spectra. NMR in biomedicine, 2015, Volume: 28, Issue:4 Topics: Animals; Aspartic Acid; Brain Chemistry; Choline; Creatine; Cuprizone; Demyelinating Diseases; Dipeptides; Disease Models, Animal; Female; Gliosis; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Neuroimaging; Oligodendroglia; Phosphocreatine; Proton Magnetic Resonance Spectroscopy	2015
Investigation of NAA and NAAG dynamics underlying visual stimulation using MEGA-PRESS in a functional MRS experiment. Magnetic resonance imaging, 2016, Volume: 34, Issue:3 Topics: Adult; Aspartic Acid; Brain; Dipeptides; Female; Glutamic Acid; Healthy Volunteers; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Neuropeptides; Vision, Ocular; Young Adult	2016
Dose-dependent inhibition of GCPII to prevent and treat cognitive impairment in the EAE model of multiple sclerosis. Brain research, 2016, Mar-15, Volume: 1635 Topics: Animals; Aspartic Acid; Cognition Disorders; Dipeptides; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamate Carboxypeptidase II; Hippocampus; Maze Learning; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Organophosphorus Compounds; Severity of Illness Index	2016
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla. Schizophrenia research, 2016, Volume: 172, Issue:1-3 Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Inositol; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2016
HERMES: Hadamard encoding and reconstruction of MEGA-edited spectroscopy. Magnetic resonance in medicine, 2016, Volume: 76, Issue:1 Topics: Adult; Algorithms; Aspartic Acid; Brain; Dipeptides; Female; Humans; Male; Molecular Imaging; Phantoms, Imaging; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results; Sensitivity and Specificity	2016
Case control study: magnetic resonance spectroscopy of brain in HIV infected patients. BMC neurology, 2016, Jul-12, Volume: 16 Topics: Adult; Aspartic Acid; Basal Ganglia; Case-Control Studies; Choline; Creatine; Dipeptides; Female; Frontal Lobe; Glutamic Acid; Glutamine; HIV Infections; Humans; Inositol; Lipid Metabolism; Macromolecular Substances; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Proton Magnetic Resonance Spectroscopy; White Matter	2016
Diagnostic and prognostic value of in vivo proton MR spectroscopy for Zellweger syndrome spectrum patients. Journal of inherited metabolic disease, 2016, Volume: 39, Issue:6 Topics: Adolescent; Adult; Aspartic Acid; Basal Ganglia; Child; Dipeptides; Female; Gray Matter; Humans; Infant; Magnetic Resonance Spectroscopy; Male; Peroxisomes; Prognosis; Protons; White Matter; Young Adult; Zellweger Syndrome	2016
In vivo neurometabolic profiling in orthostatic tremor. Medicine, 2016, Volume: 95, Issue:37 Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Case-Control Studies; Cerebellum; Cerebral Cortex; Dipeptides; Dizziness; Female; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Tremor	2016
Diagnosis and body mass index effects on hippocampal volumes and neurochemistry in bipolar disorder. Translational psychiatry, 2017, 03-28, Volume: 7, Issue:3 Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Body Mass Index; Brain; Case-Control Studies; Creatine; Dipeptides; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Obesity; Organ Size; Overweight; Phosphatidylcholines; Phosphocreatine; Young Adult	2017
Simultaneous measurement of Aspartate, NAA, and NAAG using HERMES spectral editing at 3 Tesla. NeuroImage, 2017, 07-15, Volume: 155 Topics: Adult; Aspartic Acid; Computer Simulation; Dipeptides; Female; Humans; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging; White Matter; Young Adult	2017
Region-specific aging of the human brain as evidenced by neurochemical profiles measured noninvasively in the posterior cingulate cortex and the occipital lobe using Neuroscience, 2017, 06-23, Volume: 354 Topics: Aged; Aged, 80 and over; Aging; Ascorbic Acid; Aspartic Acid; Brain Chemistry; Creatine; Dipeptides; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Phosphocreatine; Tritium; Young Adult	2017
Glutamatergic and neural dysfunction in postpartum depression using magnetic resonance spectroscopy. Psychiatry research. Neuroimaging, 2017, Jul-30, Volume: 265 Topics: Adult; Aspartic Acid; Depression, Postpartum; Dipeptides; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy	2017
Neurochemical dynamics of acute orofacial pain in the human trigeminal brainstem nuclear complex. NeuroImage, 2017, 11-15, Volume: 162 Topics: Adult; Aspartic Acid; Dipeptides; Facial Pain; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Trigeminal Nuclei; Young Adult	2017
Striatal N-Acetylaspartate Synthetase Shati/Nat8l Regulates Depression-Like Behaviors via mGluR3-Mediated Serotonergic Suppression in Mice. The international journal of neuropsychopharmacology, 2017, 12-01, Volume: 20, Issue:12 Topics: Acetyltransferases; Animals; Aspartic Acid; Corpus Striatum; Depression; Dipeptides; Disease Models, Animal; Gene Expression Regulation; Green Fluorescent Proteins; HEK293 Cells; Hindlimb Suspension; Humans; Interpersonal Relations; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Microdialysis; Microinjections; Receptors, Metabotropic Glutamate; Serotonin; Swimming; Transduction, Genetic	2017
Copper chloride dose-dependently alters spatial learning and memory, and glutamate levels, in the hippocampus of rats. Molecular medicine reports, 2018, Volume: 17, Issue:3 Topics: Animals; Aspartic Acid; Brain Chemistry; Copper; Dipeptides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Maze Learning; Memory; Phosphocreatine; Proton Magnetic Resonance Spectroscopy; Rats; Rats, Sprague-Dawley	2018
Chasing N-acetyl-L-aspartate, a shiny NMR object in the brain. NMR in biomedicine, 2018, Volume: 31, Issue:4 Topics: Aspartic Acid; Brain; Dipeptides; Humans; Magnetic Resonance Spectroscopy	2018
Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis. JAMA psychiatry, 2019, 03-01, Volume: 76, Issue:3 Topics: Aspartic Acid; Brain; Case-Control Studies; Cross-Sectional Studies; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Male; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Young Adult	2019
Validation of in vivo MRS measures of metabolite concentrations in the human brain. NMR in biomedicine, 2019, Volume: 32, Issue:3 Topics: Aspartic Acid; Brain; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Humans; Magnetic Resonance Spectroscopy; Male; Metabolome; Young Adult	2019
Role of Magnetic Resonance Spectroscopy in Evaluation of Cerebral Metabolic Status Before and After Carotid Endarterectomy/Thromboendarterectomy and Carotid Artery Stenting in Patients with Asymptomatic Critical Internal Carotid Artery Stenosis. Medical science monitor : international medical journal of experimental and clinical research, 2020, Dec-30, Volume: 26 Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Carotid Artery, Internal; Carotid Stenosis; Creatinine; Dipeptides; Endarterectomy, Carotid; Female; Glycerylphosphorylcholine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolome; Middle Aged; Middle Cerebral Artery; Phosphocreatine; Phosphorylcholine; Prospective Studies; Stents	2020
Comparison of Predictive Values of Magnetic Resonance Biomarkers Based on Scan Timing in Neonatal Encephalopathy Following Therapeutic Hypothermia. The Journal of pediatrics, 2021, Volume: 239 Topics: Aspartic Acid; Biomarkers; Brain Diseases; Dipeptides; Gray Matter; Humans; Hypothermia, Induced; Infant, Newborn; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Predictive Value of Tests; Retrospective Studies; Severity of Illness Index	2021