isospaglumic acid has been researched along with glycine in 14 studies
| Studies (isospaglumic acid) | Trials (isospaglumic acid) | Recent Studies (post-2010) (isospaglumic acid) | Studies (glycine) | Trials (glycine) | Recent Studies (post-2010) (glycine) |
|---|---|---|---|---|---|
| 469 | 31 | 116 | 35,163 | 756 | 8,415 |
| Protein | Taxonomy | isospaglumic acid (IC50) | glycine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 1.4852 | |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | 106 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | 128 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kvamme, E; Reichelt, KL; Wedege, E | 1 |
| Coyle, JT; Handen, JS; Montgomery, DT; Puttfarcken, PS; Werling, LL | 1 |
| Bischofberger, J; Schild, D | 1 |
| Bruno, V; Fiore, L; Nicoletti, F; Wroblewska, B; Wroblewski, JT | 1 |
| Akaike, N; Harata, N; Katayama, J | 1 |
| Anwyl, R; Huang, L; Rowan, MJ | 1 |
| Balcar, VJ; FitzGibbon, T; Lawrance, ML; Pliss, L; Shave, E; Stastny, F | 1 |
| Lin, Q; Liu, W; Lu, XM; Slusher, BS; Tang, Z | 1 |
| Olkowski, JL; Slusher, BS; Thomas, AG | 1 |
| Lea, PM; Sarvey, JM | 1 |
| Bergeron, R; Coyle, JT; Greene, RW; Tsai, G | 1 |
| Minabe, Y; Ogino, T; Shirayama, Y; Takahashi, S | 1 |
| Manahan-Vaughan, D; Pöschel, B | 1 |
| Raiteri, L; Raiteri, M; Romei, C | 1 |
14 other study(ies) available for isospaglumic acid and glycine
| Article | Year |
|---|---|
Effects of amines on the level of N-acetyl-aspartate and N-acetyl-aspartyl-glutamate in mouse brain tissue slices.
Topics: Acetylcholine; Adenosine; Amines; Amino Acids; Amino Alcohols; Aminobutyrates; Animals; Aspartic Acid; Basal Ganglia; Biogenic Amines; Brain; Caffeine; Cerebellum; Cerebral Cortex; Dipeptides; Dopamine; Edetic Acid; Glutamates; Glycine; Histamine; Medulla Oblongata; Mice; Norepinephrine; Pons; Puromycin; Serotonin; Spermine; Taurine | 1971 |
N-acetyl-aspartylglutamate modulation of N-methyl-D-aspartate-stimulated [3H]norepinephrine release from rat hippocampal slices.
Topics: Animals; Calcium Channel Blockers; Dipeptides; Glycine; Hippocampus; In Vitro Techniques; N-Methylaspartate; Norepinephrine; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Glutamate and N-acetylaspartylglutamate block HVA calcium currents in frog olfactory bulb interneurons via an mGluR2/3-like receptor.
Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Cyclopropanes; Dipeptides; Glutamic Acid; Glycine; Homovanillic Acid; Interneurons; Ion Channel Gating; Olfactory Bulb; Receptors, Metabotropic Glutamate; Synapses; Xenopus | 1996 |
Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Cyclopropanes; Dipeptides; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Receptors, Metabotropic Glutamate | 1998 |
Excitatory amino acid responses in relay neurons of the rat lateral geniculate nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Concanavalin A; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Geniculate Bodies; Glutamic Acid; Glycine; Ionophores; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Nystatin; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
Induction of long-lasting depression by (+)-alpha-methyl-4-carboxyphenylglycine and other group II mGlu receptor ligands in the dentate gyrus of the hippocampus in vitro.
Topics: Animals; Anticonvulsants; Benzoates; Cyclopropanes; Dentate Gyrus; Dipeptides; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamates; Glycine; Hippocampus; In Vitro Techniques; Ligands; Long-Term Potentiation; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1999 |
Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Brain Chemistry; Carboxypeptidases; Cold Temperature; Cycloleucine; Cyclopropanes; Dipeptides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamate Carboxypeptidase II; Glycine; Kainic Acid; Male; Nerve Tissue Proteins; Phosphoserine; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tetrazoles | 2001 |
N-acetylaspartylglutamate protects against transient focal cerebral ischemia in rats.
Topics: Animals; Benzoates; Brain; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Ischemic Attack, Transient; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2000 |
Neuroprotection afforded by NAAG and NAALADase inhibition requires glial cells and metabotropic glutamate receptor activation.
Topics: Animals; Benzoates; Carboxypeptidases; Cells, Cultured; Dipeptides; Excitatory Amino Acid Antagonists; Female; Glutamate Carboxypeptidase II; Glycine; Neuroglia; Neuroprotective Agents; Organophosphorus Compounds; Rats; Receptors, Metabotropic Glutamate | 2001 |
Modulation of epileptiform burst frequency by the metabotropic glutamate receptor subtype mGluR3.
Topics: Animals; Anticonvulsants; Calcium; Cerebrospinal Fluid; Cyclopropanes; Dentate Gyrus; Dipeptides; Electrophysiology; Epilepsy; Glutamates; Glycine; In Vitro Techniques; Male; Osmolar Concentration; Perfusion; Potassium; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2003 |
NAAG reduces NMDA receptor current in CA1 hippocampal pyramidal neurons of acute slices and dissociated neurons.
Topics: Animals; Cell Separation; Dipeptides; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Glycine; Hippocampus; In Vitro Techniques; Neural Conduction; Neurons; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses | 2005 |
In vitro 1H NMR spectroscopy shows an increase in N-acetylaspartylglutamate and glutamine content in the hippocampus of amygdaloid-kindled rats.
Topics: Amino Acids; Amygdala; Animals; Creatine; Dipeptides; Disease Models, Animal; Energy Metabolism; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Glycine; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Rats; Rats, Wistar; Up-Regulation | 2005 |
Group II mGluR-induced long term depression in the dentate gyrus in vivo is NMDA receptor-independent and does not require protein synthesis.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Anisomycin; Calcium Channel Blockers; Dentate Gyrus; Dipeptides; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Functional Laterality; Glycine; Long-Term Synaptic Depression; Male; Neuroprotective Agents; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors; Verapamil | 2005 |
Glycine release is regulated by metabotropic glutamate receptors sensitive to mGluR2/3 ligands and activated by N-acetylaspartylglutamate (NAAG).
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exocytosis; Glutamic Acid; Glycine; Male; Mice; Potassium Chloride; Receptors, Metabotropic Glutamate; Spinal Cord; Synaptosomes; Xanthenes | 2013 |