Page last updated: 2024-09-05

isospaglumic acid and glutamine

isospaglumic acid has been researched along with glutamine in 37 studies

Compound Research Comparison

Studies (isospaglumic acid)	Trials (isospaglumic acid)	Recent Studies (post-2010) (isospaglumic acid)	Studies (glutamine)	Trials (glutamine)	Recent Studies (post-2010) (glutamine)
469	31	116	19,062	787	5,408

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.70)	18.7374
1990's	3 (8.11)	18.2507
2000's	18 (48.65)	29.6817
2010's	14 (37.84)	24.3611
2020's	1 (2.70)	2.80

Authors

Authors	Studies
Neale, JH; Williamson, LC	1
Cangro, CB; Corigliano-Murphy, A; Namboodiri, MA; Neale, JH; Sklar, LA	1
Liptaj, T; Mierisová, S; Tkác, I; van den Boogaart, A; Van Hecke, P; Vanhamme, L	1
Bolo, N; Dahchour, A; De Witte, P; Durbin, P; Macher, JP; Muzet, M; Nédélec, JF	1
Barker, GJ; Duncan, JS; McLean, MA; Woermann, FG	1
Barker, GJ; Bartlett, PA; Duncan, JS; McLean, MA; Woermann, FG	1
Buttram, JG; Fletcher, PL; Gafurov, BS; Grossfeld, RM; Lieberman, EM; Speno, H; Urazaev, AK	1
Buttram, JG; Engler, JA; Grossfeld, RM; Lieberman, EM; Urazaev, AKh	1
Bernsen, H; Boerman, R; Heerschap, A; Rijpkema, M; Schuuring, J; van der Graaf, M; van der Kogel, A; van der Meulen, Y	1
Hurd, R; Nelson, SJ; Pelletier, D; Sailasuta, N; Srinivasan, R; Vigneron, DB	1
Arun, P; Hershfield, JR; Madhavarao, CN; Moffett, JR; Namboodiri, MA	1
Bzdega, T; Gehl, LM; Neale, JH; Saab, OH; Wroblewska, B	1
Juchem, C; Logothetis, NK; Merkle, H; Nauerth, A; Pfeuffer, J	1
Ambrosini, A; Colonnese, C; Garreffa, G; Giove, F; Guardati, M; Macrì, MA; Maraviglia, B	1
Minabe, Y; Ogino, T; Shirayama, Y; Takahashi, S	1
Brockmann, K; Dechent, P; Frahm, J; Hanefeld, FA; Pouwels, PJ; Wilken, B	1
Arun, P; Madhavarao, CN; Moffett, JR; Namboodiri, MA	1
Doelken, M; Doerfler, A; Engelhorn, T; Ganslandt, O; Hammen, T; Kerling, F; Nimsky, C; Schwarz, M; Stadlbauer, A; Stefan, H	1
Barker, GJ; Duncan, JS; McLean, MA; Simister, RJ	1
Baker, EH; Barker, PB; Basso, G; Bonekamp, D; Horská, A; Smith, MA	1
Danielsen, ER; Dock, J; Elberling, TV; Feldt-Rasmussen, U; Hørding, M; Perrild, H; Rasmussen, AK; Thomsen, C; Waldemar, G	1
Becerra, L; Borsook, D; Burstein, R; Hargreaves, R; Jensen, E; Pendse, G; Prescot, A; Renshaw, P; Tully, S	1
Artal, J; Fayed, N; Modrego, PJ; Olmos, S	1
Igarashi, H; Nakada, T; Nishizawa, M; Okamoto, K; Ozawa, T; Shimohata, T; Takado, Y; Terajima, K	1
Georgieff, MK; Rao, R; Schmidt, AT; Tkac, I	1
Clark, VP; Coffman, BA; Gasparovic, C; Trumbo, MC	1
Bacci, A; Feraco, P; Leonardi, M; Malavolta, N; Passamonti, L; Pedrabissi, F; Zampogna, G	1
Fei, S; Ji, Y; Rao, S; Wang, H; Yao, X; Zeng, M	1
Chang, S; Feusner, JD; Gorbis, E; Levitt, JG; Maidment, KM; O'Neill, J; Ringman, JM; Salamon, N; Saxena, S; Yip, JC	1
An, Z; Banerjee, A; Choi, C; Ganji, SK; Hulsey, KM; Madan, A	1
Fievisohn, EM; Hardy, WN; Sajja, VS; Vandevord, PJ	1
Barker, PB; Brandt, AS; Churchill, G; Edden, RA; Harris, AD; Hua, J; Lim, IA; Margolis, RL; Pradhan, S; Ross, CA; Unschuld, PG; van Zijl, PC	1
Bairwa, D; Das, BK; Jagannathan, NR; Kumar, V; Pandey, RM; Sharma, SK; Sinha, S; Srivastava, AK; Vyas, S	1
Brooks, SJ; Burger, A; Howells, FM; Stein, DJ	1
Barker, PB; Coughlin, JM; Crawford, JL; DuBois, SL; Nestadt, G; Nucifora, FC; Nucifora, LG; Pradhan, S; Sawa, A; Schretlen, DJ; Sedlak, TW; Trivedi, A; Wang, AM	1
Abdelkefi, I; Dhamala, E; Hennessy, TJ; Nadeau, H; Near, J; Nguyen, M	1
Andronesi, O; Bogner, W; Dydak, U; Ma, RE; Murdoch, JB	1

Trials

6 trial(s) available for isospaglumic acid and glutamine

Article	Year
Central effects of acamprosate: part 2. Acamprosate modifies the brain in-vivo proton magnetic resonance spectrum in healthy young male volunteers. Psychiatry research, 1998, May-20, Volume: 82, Issue:2 Topics: Acamprosate; Adult; Alcohol Deterrents; Aspartic Acid; Brain; Creatine; Cross-Over Studies; Dipeptides; Double-Blind Method; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Taurine	1998
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter. Magnetic resonance in medicine, 2000, Volume: 44, Issue:3 Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Phantoms, Imaging; Regression Analysis; Sensitivity and Specificity	2000
Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy. Brain : a journal of neurology, 2001, Volume: 124, Issue:Pt 2 Topics: Adult; Analysis of Variance; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Male; Middle Aged; Nervous System Malformations; Phosphocreatine; Reference Values	2001
Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging. NMR in biomedicine, 2003, Volume: 16, Issue:1 Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oligodendroglioma; Reproducibility of Results; Sensitivity and Specificity	2003
Brainstem metabolites in multiple system atrophy of cerebellar type: 3.0-T magnetic resonance spectroscopy study. Movement disorders : official journal of the Movement Disorder Society, 2011, Volume: 26, Issue:7 Topics: Aged; Aspartic Acid; Biomarkers; Choline; Creatinine; Dipeptides; Feasibility Studies; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Medulla Oblongata; Middle Aged; Multiple System Atrophy; Pons; Protons; Severity of Illness Index	2011
Metabolic abnormalities in pain-processing regions of patients with fibromyalgia: a 3T MR spectroscopy study. AJNR. American journal of neuroradiology, 2011, Volume: 32, Issue:9 Topics: Adult; Aspartic Acid; Choline; Chronic Pain; Creatinine; Dipeptides; Female; Fibromyalgia; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Thalamus	2011

Other Studies

31 other study(ies) available for isospaglumic acid and glutamine

Article	Year
Uptake, metabolism, and release of N-[3H]acetylaspartylglutamate by the avian retina. Journal of neurochemistry, 1992, Volume: 58, Issue:6 Topics: Animals; Aspartic Acid; Biological Transport; Chickens; Dipeptides; Glutamates; Glutamic Acid; Glutamine; Histamine H1 Antagonists; Retina; Time Factors; Tritium	1992
Immunohistochemistry and biosynthesis of N-acetylaspartylglutamate in spinal sensory ganglia. Journal of neurochemistry, 1987, Volume: 49, Issue:5 Topics: Amino Acids; Animals; Anisomycin; Aspartic Acid; Chromatography, High Pressure Liquid; Cycloheximide; Dipeptides; Ganglia; Ganglia, Spinal; Glutamates; Glutamic Acid; Glutamine; Histocytochemistry; Immunologic Techniques; Male; Neurons; Rats; Rats, Inbred Strains	1987
New approach for quantitation of short echo time in vivo 1H MR spectra of brain using AMARES. NMR in biomedicine, 1998, Volume: 11, Issue:1 Topics: Algorithms; Animals; Aspartic Acid; Brain; Choline; Creatine; Dipeptides; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Magnetic Resonance Imaging; Male; Rats; Rats, Wistar; Software; Time Factors	1998
Synthesis and release of N-acetylaspartylglutamate (NAAG) by crayfish nerve fibers: implications for axon-glia signaling. Neuroscience, 2001, Volume: 106, Issue:1 Topics: Animals; Aspartic Acid; Astacoidea; Axons; Carbon Radioisotopes; Carboxypeptidases; Cell Communication; Culture Media; Cytoplasm; Dipeptides; Electric Stimulation; gamma-Aminobutyric Acid; Glutamate Carboxypeptidase II; Glutamic Acid; Glutamine; Nervous System; Neuroglia; Organ Culture Techniques; Quisqualic Acid; Signal Transduction; Tritium	2001
Glutamine uptake and metabolism to N-acetylaspartylglutamate (NAAG) by crayfish axons and glia. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2002, Volume: 133, Issue:2 Topics: Amino Acids; Animals; Astacoidea; Axons; Dipeptides; Glutamine; Neuroglia; Neurotransmitter Agents; Radioactive Tracers; Sodium; Tritium	2002
Measurement of brain glutamate using TE-averaged PRESS at 3T. Magnetic resonance in medicine, 2004, Volume: 51, Issue:3 Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Dipeptides; Female; Fourier Analysis; Glutamic Acid; Glutamine; Humans; Image Enhancement; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropeptides; Reproducibility of Results	2004
SH-SY5Y neuroblastoma cells: a model system for studying biosynthesis of NAAG. Neuroreport, 2004, May-19, Volume: 15, Issue:7 Topics: Cell Line, Tumor; Dipeptides; Glutamine; Humans; Neuroblastoma	2004
Biosynthesis of NAAG by an enzyme-mediated process in rat central nervous system neurons and glia. Journal of neurochemistry, 2004, Volume: 90, Issue:4 Topics: Animals; Aspartic Acid; Cells, Cultured; Central Nervous System; Cerebellum; Cerebral Cortex; Culture Media, Serum-Free; Dipeptides; Enzymes; Glutamic Acid; Glutamine; Neuroglia; Neurons; Potassium Chloride; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Spinal Cord; Tritium	2004
High-field localized 1H NMR spectroscopy in the anesthetized and in the awake monkey. Magnetic resonance imaging, 2004, Volume: 22, Issue:10 Topics: Anesthesia, General; Animals; Artifacts; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Dipeptides; Glutamic Acid; Glutamine; Glutathione; Hydrogen; Image Enhancement; Inositol; Lactic Acid; Macaca mulatta; Magnetic Resonance Spectroscopy; Phosphocreatine; Stereoisomerism; Taurine; Wakefulness	2004
In vivo quantitative 1H MRS of cerebellum and evaluation of quantitation reproducibility by simulation of different levels of noise and spectral resolution. Magnetic resonance imaging, 2004, Volume: 22, Issue:10 Topics: Adult; Artifacts; Aspartic Acid; Body Water; Cerebellum; Choline; Creatine; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Hydrogen; Image Enhancement; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Neuropeptides	2004
In vitro 1H NMR spectroscopy shows an increase in N-acetylaspartylglutamate and glutamine content in the hippocampus of amygdaloid-kindled rats. Journal of neurochemistry, 2005, Volume: 92, Issue:6 Topics: Amino Acids; Amygdala; Animals; Creatine; Dipeptides; Disease Models, Animal; Energy Metabolism; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Glycine; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Rats; Rats, Wistar; Up-Regulation	2005
Quantitative proton MRS of Pelizaeus-Merzbacher disease: evidence of dys- and hypomyelination. Neurology, 2005, Sep-13, Volume: 65, Issue:5 Topics: Aspartic Acid; Basal Ganglia; Brain; Cerebral Cortex; Child; Child, Preschool; Choline; Creatine; Dipeptides; Down-Regulation; Glutamine; Humans; Infant; Inositol; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Pelizaeus-Merzbacher Disease; Phosphocreatine; Predictive Value of Tests; Protons; Up-Regulation	2005
Regulation of N-acetylaspartate and N-acetylaspartylglutamate biosynthesis by protein kinase activators. Journal of neurochemistry, 2006, Volume: 98, Issue:6 Topics: Aspartic Acid; Bucladesine; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Dipeptides; Dose-Response Relationship, Drug; Enzyme Activation; Glutamine; Humans; Neuroblastoma; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Time Factors	2006
1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG. Epilepsia, 2007, Volume: 48, Issue:2 Topics: Adult; Aspartic Acid; Biomarkers; Brain Mapping; Choline; Creatine; Dipeptides; Electroencephalography; Epilepsy, Temporal Lobe; Female; Functional Laterality; Glutamine; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Monitoring, Physiologic; Seizures; Severity of Illness Index; Temporal Lobe; Videotape Recording	2007
The effect of sodium valproate on proton MRS visible neurochemical concentrations. Epilepsy research, 2007, Volume: 74, Issue:2-3 Topics: Adolescent; Adult; Algorithms; Anticonvulsants; Brain Chemistry; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Valproic Acid	2007
Regional apparent metabolite concentrations in young adult brain measured by (1)H MR spectroscopy at 3 Tesla. Journal of magnetic resonance imaging : JMRI, 2008, Volume: 27, Issue:3 Topics: Adult; Age Factors; Aspartic Acid; Brain Chemistry; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male	2008
Reduced parietooccipital white matter glutamine measured by proton magnetic resonance spectroscopy in treated graves' disease patients. The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8 Topics: Adult; Aspartic Acid; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Graves Disease; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Parietal Lobe; Prospective Studies	2008
Excitatory neurotransmitters in brain regions in interictal migraine patients. Molecular pain, 2009, Jun-30, Volume: 5 Topics: Adult; Brain Chemistry; Brain Mapping; Case-Control Studies; Cerebral Cortex; Diffusion Magnetic Resonance Imaging; Dipeptides; Excitatory Amino Acid Agents; Female; Glutamine; Humans; Male; Middle Aged; Migraine Disorders; Neurotransmitter Agents	2009
Correlation of findings in advanced MRI techniques with global severity scales in patients with Parkinson disease. Academic radiology, 2011, Volume: 18, Issue:2 Topics: Aged; Brain; Choline; Corpus Striatum; Creatine; Diffusion Tensor Imaging; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Parkinson Disease; Severity of Illness Index; Substantia Nigra	2011
Fetal and neonatal iron deficiency causes volume loss and alters the neurochemical profile of the adult rat hippocampus. Nutritional neuroscience, 2011, Volume: 14, Issue:2 Topics: Anatomy, Cross-Sectional; Animals; Animals, Newborn; Creatine; Dipeptides; Female; Fetus; Glutamine; Hippocampus; Iron Deficiencies; Iron, Dietary; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Neurochemistry; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Taurine; Time	2011
Transcranial direct current stimulation (tDCS) produces localized and specific alterations in neurochemistry: a ¹H magnetic resonance spectroscopy study. Neuroscience letters, 2011, Aug-01, Volume: 500, Issue:1 Topics: Adult; Aspartic Acid; Brain; Cerebrum; Dipeptides; Electric Stimulation; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Young Adult	2011
Metabolite detection of pancreatic carcinoma by in vivo proton MR spectroscopy at 3T: initial results. La Radiologia medica, 2012, Volume: 117, Issue:5 Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Choline; Dipeptides; Fatty Acids, Unsaturated; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pancreatic Neoplasms; Software	2012
Effects of intensive cognitive-behavioral therapy on cingulate neurochemistry in obsessive-compulsive disorder. Journal of psychiatric research, 2013, Volume: 47, Issue:4 Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Cognitive Behavioral Therapy; Dipeptides; Follow-Up Studies; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurochemistry; Obsessive-Compulsive Disorder; Pilot Projects; Severity of Illness Index	2013
Measurement of regional variation of GABA in the human brain by optimized point-resolved spectroscopy at 7 T in vivo. NMR in biomedicine, 2014, Volume: 27, Issue:10 Topics: Adult; Cerebral Cortex; Choline; Computer Simulation; Creatine; Dipeptides; Feasibility Studies; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glutathione; Humans; Male; Occipital Lobe; Phantoms, Imaging; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Protons; White Matter; Young Adult	2014
Evaluation of impact-induced traumatic brain injury in the Göttingen Minipig using two input modes. Traffic injury prevention, 2014, Volume: 15 Suppl 1 Topics: Animals; Aspartic Acid; Brain Injuries; Dipeptides; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Swine; Swine, Miniature	2014
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla. Schizophrenia research, 2016, Volume: 172, Issue:1-3 Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Inositol; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2016
Case control study: magnetic resonance spectroscopy of brain in HIV infected patients. BMC neurology, 2016, Jul-12, Volume: 16 Topics: Adult; Aspartic Acid; Basal Ganglia; Case-Control Studies; Choline; Creatine; Dipeptides; Female; Frontal Lobe; Glutamic Acid; Glutamine; HIV Infections; Humans; Inositol; Lipid Metabolism; Macromolecular Substances; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Proton Magnetic Resonance Spectroscopy; White Matter	2016
The impact of acute and short-term methamphetamine abstinence on brain metabolites: A proton magnetic resonance spectroscopy chemical shift imaging study. Drug and alcohol dependence, 2018, 04-01, Volume: 185 Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Brain; Choline; Creatine; Dipeptides; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Male; Methamphetamine; Neurons; Proton Magnetic Resonance Spectroscopy; Young Adult	2018
Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis. JAMA psychiatry, 2019, 03-01, Volume: 76, Issue:3 Topics: Aspartic Acid; Brain; Case-Control Studies; Cross-Sectional Studies; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Male; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Young Adult	2019
Validation of in vivo MRS measures of metabolite concentrations in the human brain. NMR in biomedicine, 2019, Volume: 32, Issue:3 Topics: Aspartic Acid; Brain; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Humans; Magnetic Resonance Spectroscopy; Male; Metabolome; Young Adult	2019
Atlas-based GABA mapping with 3D MEGA-MRSI: Cross-correlation to single-voxel MRS. NMR in biomedicine, 2021, Volume: 34, Issue:5 Topics: Adult; Creatinine; Dipeptides; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Middle Aged; Young Adult	2021