isospaglumic acid has been researched along with gamma-aminobutyric acid in 30 studies
| Studies (isospaglumic acid) | Trials (isospaglumic acid) | Recent Studies (post-2010) (isospaglumic acid) | Studies (gamma-aminobutyric acid) | Trials (gamma-aminobutyric acid) | Recent Studies (post-2010) (gamma-aminobutyric acid) |
|---|---|---|---|---|---|
| 469 | 31 | 116 | 40,215 | 1,423 | 9,631 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.67) | 18.7374 |
| 1990's | 7 (23.33) | 18.2507 |
| 2000's | 9 (30.00) | 29.6817 |
| 2010's | 10 (33.33) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bixler, MA; Coyle, JT; Koller, KJ; Meyerhoff, JL; Robinson, MB | 1 |
| Neale, JH; Williamson, LC | 1 |
| Bondarenko, TI; Khodakova, AA; Mendzheritskaia, LG | 1 |
| Tieman, SB; Xing, LC | 1 |
| Bhakoo, KK; Florian, CL; Noble, MD; Williams, SR | 1 |
| Corsi, L; De Blas, AL; Ghose, S; Grayson, DR; Neale, JH; Vicini, S; Wroblewska, B | 1 |
| Liptaj, T; Mierisová, S; Tkác, I; van den Boogaart, A; Van Hecke, P; Vanhamme, L | 1 |
| Chang, R; Chen, S; Coyle, JT; Linnoila, VM; Ragan, P; Tsai, GE | 1 |
| Bolo, N; Dahchour, A; De Witte, P; Durbin, P; Macher, JP; Muzet, M; Nédélec, JF | 1 |
| Bzdega, T; Cappiello, M; Neale, JH; Ramadan, E; Wroblewska, B; Zhao, J | 1 |
| Buttram, JG; Fletcher, PL; Gafurov, BS; Grossfeld, RM; Lieberman, EM; Speno, H; Urazaev, AK | 1 |
| Moffett, JR | 1 |
| Campbell, GA; Ezell, EL; Matalon, R; Michals-Matalon, K; Quast, MJ; Rady, PL; Rassin, DK; Surendran, S; Szucs, S; Tyring, SK; Wei, J | 1 |
| Minabe, Y; Ogino, T; Shirayama, Y; Takahashi, S | 1 |
| Berman, RF; Bzdega, T; Jiang, J; Kozikowski, AP; Lyeth, BG; Neale, JH; O'Connor, WT; Smyth, A; Van, KC; Zhao, X; Zhong, C; Zhou, J | 1 |
| Matalon, R; Michals-Matalon, K; Surendran, S; Tyring, SK | 1 |
| Connor, JR; Ill, AM; Mitchell, TR; Neely, EB | 1 |
| Neale, SA; Salt, TE | 1 |
| Behar, KL; Gomez, R; Guidone, E; Gulanski, B; Jiang, L; Koretski, J; Krystal, JH; Mason, GF; Petrakis, IL; Pittman, B; Sanacora, G; Watzl, J; Weinzimer, SA | 1 |
| Barker, PB; Edden, RA; Holcomb, HH; Kontson, K; Rowland, LM; West, J; Wijtenburg, SA; Zhu, H | 1 |
| Ally, BA; Donahue, MJ; Hussey, E; Mason, E; Pradhan, S; Rane, S; Waddell, KW | 1 |
| An, Z; Banerjee, A; Choi, C; Ganji, SK; Hulsey, KM; Madan, A | 1 |
| Fievisohn, EM; Hardy, WN; Sajja, VS; Vandevord, PJ | 1 |
| Barker, PB; Brandt, AS; Churchill, G; Edden, RA; Harris, AD; Hua, J; Lim, IA; Margolis, RL; Pradhan, S; Ross, CA; Unschuld, PG; van Zijl, PC | 1 |
| Brügger, M; de Matos, NMP; Ettlin, DA; Hock, A; Wyss, M | 1 |
| Chen, Y; Gao, W; Li, Q; Liu, S; Liu, W; Shen, Z; Wu, R; Zhang, G | 1 |
| Barker, PB; Coughlin, JM; Crawford, JL; DuBois, SL; Nestadt, G; Nucifora, FC; Nucifora, LG; Pradhan, S; Sawa, A; Schretlen, DJ; Sedlak, TW; Trivedi, A; Wang, AM | 1 |
| Abdelkefi, I; Dhamala, E; Hennessy, TJ; Nadeau, H; Near, J; Nguyen, M | 1 |
| Andronesi, O; Bogner, W; Dydak, U; Ma, RE; Murdoch, JB | 1 |
| Attarwala, N; Cooper, AJL; Hoang, G; Jung, JG; Le, A; Zhang, C | 1 |
1 review(s) available for isospaglumic acid and gamma-aminobutyric acid
| Article | Year |
|---|---|
Canavan disease: studies on the knockout mouse.
Topics: Amidohydrolases; Animals; Canavan Disease; Dipeptides; gamma-Aminobutyric Acid; Gene Targeting; Genetic Therapy; Glutamic Acid; Humans; Mice; Mice, Knockout; Phenotype; Stem Cell Transplantation | 2006 |
2 trial(s) available for isospaglumic acid and gamma-aminobutyric acid
| Article | Year |
|---|---|
Central effects of acamprosate: part 2. Acamprosate modifies the brain in-vivo proton magnetic resonance spectrum in healthy young male volunteers.
Topics: Acamprosate; Adult; Alcohol Deterrents; Aspartic Acid; Brain; Creatine; Cross-Over Studies; Dipeptides; Double-Blind Method; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Taurine | 1998 |
Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla.
Topics: Adult; Aspartic Acid; Breath Tests; Cerebral Cortex; Dipeptides; Ethanol; Female; gamma-Aminobutyric Acid; Humans; Infusions, Intravenous; Magnetic Resonance Spectroscopy; Male | 2012 |
27 other study(ies) available for isospaglumic acid and gamma-aminobutyric acid
| Article | Year |
|---|---|
Kindling increases brain levels of NAAG and seizures reduce activity of a NAAG-hydrolyzing enzyme, NAALADase.
Topics: Amygdala; Animals; Aspartic Acid; Brain; Brain Mapping; Dipeptidases; Dipeptides; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate Carboxypeptidase II; Glutamates; Glutamic Acid; Kindling, Neurologic; Male; Rats; Rats, Sprague-Dawley; Seizures | 1992 |
Calcium-dependent release of N-acetylaspartylglutamate from retinal neurons upon depolarization.
Topics: Animals; Calcium; Dipeptides; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Potassium; Ranidae; Retina | 1988 |
[Age and the role of certain mediators in the sensitivity of animals to hyperbaric oxygenation].
Topics: Age Factors; Animals; Brain Chemistry; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Histamine; Histidine; Hyperbaric Oxygenation; Neurotransmitter Agents; Rabbits; Rats | 1980 |
Relay cells, not interneurons, of cat's lateral geniculate nucleus contain N-acetylaspartylglutamate.
Topics: Animals; Cats; Dipeptides; Fluorescent Dyes; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamate Decarboxylase; Histamine H1 Antagonists; Immunohistochemistry; Interneurons; Neurons; Tissue Fixation | 1993 |
Regional and developmental variations in metabolite concentration in the rat brain and eye: a study using 1H NMR spectroscopy and high performance liquid chromatography.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Callosum; Dipeptides; Eye; gamma-Aminobutyric Acid; Glutamic Acid; Hydrogen; Magnetic Resonance Spectroscopy; Olfactory Bulb; Oligodendroglia; Optic Nerve; Organ Specificity; Rats; Stem Cells | 1996 |
N-acetylaspartylglutamate stimulates metabotropic glutamate receptor 3 to regulate expression of the GABA(A) alpha6 subunit in cerebellar granule cells.
Topics: Animals; Cells, Cultured; Cerebellum; Colforsin; Cyclic AMP; Dipeptides; Electric Conductivity; Furosemide; gamma-Aminobutyric Acid; Ion Channel Gating; Neurons; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Metabotropic Glutamate; RNA, Messenger; Transcription, Genetic | 1997 |
New approach for quantitation of short echo time in vivo 1H MR spectra of brain using AMARES.
Topics: Algorithms; Animals; Aspartic Acid; Brain; Choline; Creatine; Dipeptides; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Magnetic Resonance Imaging; Male; Rats; Rats, Wistar; Software; Time Factors | 1998 |
Increased glutamatergic neurotransmission and oxidative stress after alcohol withdrawal.
Topics: Adult; Alcoholism; Aspartic Acid; Dipeptides; Ethanol; Excitatory Amino Acids; Female; gamma-Aminobutyric Acid; Glutamates; Humans; Male; Middle Aged; Oxidative Stress; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Superoxide Dismutase; Synaptic Transmission; Up-Regulation | 1998 |
NAAG inhibits KCl-induced [(3)H]-GABA release via mGluR3, cAMP, PKA and L-type calcium conductance.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dipeptides; gamma-Aminobutyric Acid; Neurons; Neuroprotective Agents; Nifedipine; Potassium Chloride; Presynaptic Terminals; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin; Tritium | 2001 |
Synthesis and release of N-acetylaspartylglutamate (NAAG) by crayfish nerve fibers: implications for axon-glia signaling.
Topics: Animals; Aspartic Acid; Astacoidea; Axons; Carbon Radioisotopes; Carboxypeptidases; Cell Communication; Culture Media; Cytoplasm; Dipeptides; Electric Stimulation; gamma-Aminobutyric Acid; Glutamate Carboxypeptidase II; Glutamic Acid; Glutamine; Nervous System; Neuroglia; Organ Culture Techniques; Quisqualic Acid; Signal Transduction; Tritium | 2001 |
Reductions in N-acetylaspartylglutamate and the 67 kDa form of glutamic acid decarboxylase immunoreactivities in the visual system of albino and pigmented rats after optic nerve transections.
Topics: Animals; Brain; Dipeptides; Down-Regulation; Functional Laterality; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamate Decarboxylase; Immunohistochemistry; Interneurons; Isoenzymes; Male; Neural Inhibition; Optic Nerve; Presynaptic Terminals; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Retinal Ganglion Cells; Superior Colliculi; Visual Pathways | 2003 |
Expression of glutamate transporter, GABRA6, serine proteinase inhibitor 2 and low levels of glutamate and GABA in the brain of knock-out mouse for Canavan disease.
Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Azo Compounds; Brain Chemistry; Canavan Disease; Creatine; Dipeptides; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Insect Proteins; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, Protein | 2003 |
In vitro 1H NMR spectroscopy shows an increase in N-acetylaspartylglutamate and glutamine content in the hippocampus of amygdaloid-kindled rats.
Topics: Amino Acids; Amygdala; Animals; Creatine; Dipeptides; Disease Models, Animal; Energy Metabolism; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Glycine; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Rats; Rats, Wistar; Up-Regulation | 2005 |
NAAG peptidase inhibitor increases dialysate NAAG and reduces glutamate, aspartate and GABA levels in the dorsal hippocampus following fluid percussion injury in the rat.
Topics: Animals; Aspartic Acid; Brain Injuries; Cytoprotection; Dipeptides; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamate Carboxypeptidase II; Glutamic Acid; Hippocampus; Male; Microdialysis; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Up-Regulation | 2006 |
Metabolic analysis of mouse brains that have compromised iron storage.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Choline; Dipeptides; Ferritins; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Iron Metabolism Disorders; Magnetic Resonance Spectroscopy; Mice; Neostriatum; Principal Component Analysis | 2006 |
Modulation of GABAergic inhibition in the rat superior colliculus by a presynaptic group II metabotropic glutamate receptor.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Dipeptides; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neural Inhibition; Patch-Clamp Techniques; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Superior Colliculi; Synaptic Transmission; Time Factors; Visual Pathways | 2006 |
In vivo measurements of glutamate, GABA, and NAAG in schizophrenia.
Topics: Adult; Age Factors; Attention; Cerebrum; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schizophrenia; Severity of Illness Index; Young Adult | 2013 |
γ-Aminobutyric acid (GABA) concentration inversely correlates with basal perfusion in human occipital lobe.
Topics: Adult; Aspartic Acid; Blood Volume; Cerebrovascular Circulation; Dipeptides; gamma-Aminobutyric Acid; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Occipital Lobe; Spin Labels; Young Adult | 2014 |
Measurement of regional variation of GABA in the human brain by optimized point-resolved spectroscopy at 7 T in vivo.
Topics: Adult; Cerebral Cortex; Choline; Computer Simulation; Creatine; Dipeptides; Feasibility Studies; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glutathione; Humans; Male; Occipital Lobe; Phantoms, Imaging; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Protons; White Matter; Young Adult | 2014 |
Evaluation of impact-induced traumatic brain injury in the Göttingen Minipig using two input modes.
Topics: Animals; Aspartic Acid; Brain Injuries; Dipeptides; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Swine; Swine, Miniature | 2014 |
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla.
Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Inositol; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia | 2016 |
Neurochemical dynamics of acute orofacial pain in the human trigeminal brainstem nuclear complex.
Topics: Adult; Aspartic Acid; Dipeptides; Facial Pain; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Trigeminal Nuclei; Young Adult | 2017 |
Copper chloride dose-dependently alters spatial learning and memory, and glutamate levels, in the hippocampus of rats.
Topics: Animals; Aspartic Acid; Brain Chemistry; Copper; Dipeptides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Maze Learning; Memory; Phosphocreatine; Proton Magnetic Resonance Spectroscopy; Rats; Rats, Sprague-Dawley | 2018 |
Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis.
Topics: Aspartic Acid; Brain; Case-Control Studies; Cross-Sectional Studies; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Male; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Young Adult | 2019 |
Validation of in vivo MRS measures of metabolite concentrations in the human brain.
Topics: Aspartic Acid; Brain; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Humans; Magnetic Resonance Spectroscopy; Male; Metabolome; Young Adult | 2019 |
Atlas-based GABA mapping with 3D MEGA-MRSI: Cross-correlation to single-voxel MRS.
Topics: Adult; Creatinine; Dipeptides; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Middle Aged; Young Adult | 2021 |
Uncovering metabolic reservoir cycles in MYC-transformed lymphoma B cells using stable isotope resolved metabolomics.
Topics: Carbon Isotopes; Cell Line, Tumor; Dipeptides; gamma-Aminobutyric Acid; Humans; Isotope Labeling; Lymphoma, B-Cell; Metabolomics; Proto-Oncogene Proteins c-myc | 2021 |