isospaglumic acid has been researched along with choline in 41 studies
Studies (isospaglumic acid) | Trials (isospaglumic acid) | Recent Studies (post-2010) (isospaglumic acid) | Studies (choline) | Trials (choline) | Recent Studies (post-2010) (choline) |
---|---|---|---|---|---|
469 | 31 | 116 | 19,628 | 608 | 4,345 |
Protein | Taxonomy | isospaglumic acid (IC50) | choline (IC50) |
---|---|---|---|
Sodium- and chloride-dependent creatine transporter 1 | Rattus norvegicus (Norway rat) | 1.6 | |
High affinity choline transporter 1 | Mus musculus (house mouse) | 1.6 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 6 (14.63) | 18.2507 |
2000's | 20 (48.78) | 29.6817 |
2010's | 15 (36.59) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Dreher, W; Leibfritz, D | 1 |
Bedell, BJ; Doyle, TJ; Narayana, PA | 1 |
Bruhn, H; Frahm, J; Hänicke, W; Merboldt, KD; Michaelis, T | 1 |
Comair, YG; Hong, SC; Lüders, HO; Najm, IM; Ng, TC; Wang, Y | 1 |
Frahm, J; Pouwels, PJ | 1 |
Liptaj, T; Mierisová, S; Tkác, I; van den Boogaart, A; Van Hecke, P; Vanhamme, L | 1 |
Barker, GJ; Duncan, JS; McLean, MA; Woermann, FG | 1 |
Barker, GJ; Bartlett, PA; Duncan, JS; McLean, MA; Woermann, FG | 1 |
Barker, GJ; Duncan, JS; McLean, MA; Simister, RJ; Woermann, FG | 1 |
Heerschap, A; Kok, RD; Nijland, R; van den Berg, PP; van den Bergh, AJ | 1 |
Bernsen, H; Boerman, R; Heerschap, A; Rijpkema, M; Schuuring, J; van der Graaf, M; van der Kogel, A; van der Meulen, Y | 1 |
Brockmann, K; Dechent, P; Frahm, J; Hanefeld, F; Rusch, O; Wilken, B | 1 |
Hurd, R; Nelson, SJ; Pelletier, D; Sailasuta, N; Srinivasan, R; Vigneron, DB | 1 |
Juchem, C; Logothetis, NK; Merkle, H; Nauerth, A; Pfeuffer, J | 1 |
Ambrosini, A; Colonnese, C; Garreffa, G; Giove, F; Guardati, M; Macrì, MA; Maraviglia, B | 1 |
Brockmann, K; Dechent, P; Frahm, J; Hanefeld, FA; Pouwels, PJ; Wilken, B | 1 |
Dunham, SA; Knight-Scott, J; Shanbhag, DD | 1 |
Altmann, DR; Chard, DT; Davies, G; Griffin, CM; McLean, MA; Miller, DH; Rashid, W; Sastre-Garriga, J; Thompson, AJ; Tiberio, M | 1 |
Brockmann, K; Dechent, P; Frahm, J; Groeschel, S; Hanefeld, F; Wilichowski, E | 1 |
Connor, JR; Ill, AM; Mitchell, TR; Neely, EB | 1 |
Lavebratt, C; Spenger, C; Wahlund, LO; Westman, E | 1 |
Doelken, M; Doerfler, A; Engelhorn, T; Ganslandt, O; Hammen, T; Kerling, F; Nimsky, C; Schwarz, M; Stadlbauer, A; Stefan, H | 1 |
Charlton, RA; Howe, FA; Markus, HS; McIntyre, DJ | 1 |
Baker, EH; Barker, PB; Basso, G; Bonekamp, D; Horská, A; Smith, MA | 1 |
Danielsen, ER; Dock, J; Elberling, TV; Feldt-Rasmussen, U; Hørding, M; Perrild, H; Rasmussen, AK; Thomsen, C; Waldemar, G | 1 |
Barker, GJ; Duncan, JS; McLean, MA; Salmenpera, TM; Simister, RJ | 1 |
Arvanitis, D; Bokemeyer, M; Ding, XQ; Goldbecker, A; Heeren, M; Lanfermann, H; Raab, P; Tillmann, HL; Weissenborn, K | 1 |
Artal, J; Fayed, N; Modrego, PJ; Olmos, S | 1 |
Igarashi, H; Nakada, T; Nishizawa, M; Okamoto, K; Ozawa, T; Shimohata, T; Takado, Y; Terajima, K | 1 |
Bacci, A; Feraco, P; Leonardi, M; Malavolta, N; Passamonti, L; Pedrabissi, F; Zampogna, G | 1 |
Caplan, R; Hudkins, M; Levitt, J; O'Neill, J; Seese, RR; Siddarth, P; Tseng, B; Wu, KN | 1 |
Fei, S; Ji, Y; Rao, S; Wang, H; Yao, X; Zeng, M | 1 |
Chang, S; Feusner, JD; Gorbis, E; Levitt, JG; Maidment, KM; O'Neill, J; Ringman, JM; Salamon, N; Saxena, S; Yip, JC | 1 |
Andrews-Shigaki, B; Ariyannur, PS; Arun, P; Barry, ES; Bosomtwi, A; Grunberg, NE; Moffett, JR; Namboodiri, AM; Selwyn, R; Tang, H | 1 |
He, Z; Tan, C; Yuan, F; Zhou, B | 1 |
An, Z; Banerjee, A; Choi, C; Ganji, SK; Hulsey, KM; Madan, A | 1 |
Berneman, Z; Daans, J; Guglielmetti, C; Hens, N; Kara, F; Orije, J; Ponsaerts, P; Praet, J; Santermans, E; Van der Linden, A; Verhoye, M | 1 |
Bentzley, JP; Brown, T; Hope, K; Jenkins, DD; Johnson, CB; Katikaneni, LD; Lambert, D; Morgan, PS; Mulvihill, DM; Ramakrishnan, V; Rollins, LG | 1 |
Barker, PB; Brandt, AS; Churchill, G; Edden, RA; Harris, AD; Hua, J; Lim, IA; Margolis, RL; Pradhan, S; Ross, CA; Unschuld, PG; van Zijl, PC | 1 |
Bairwa, D; Das, BK; Jagannathan, NR; Kumar, V; Pandey, RM; Sharma, SK; Sinha, S; Srivastava, AK; Vyas, S | 1 |
Brooks, SJ; Burger, A; Howells, FM; Stein, DJ | 1 |
7 trial(s) available for isospaglumic acid and choline
Article | Year |
---|---|
Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Cerebellum; Cerebral Cortex; Choline; Dipeptides; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Protons; Reference Values; Sex Factors; Thalamus | 1998 |
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Phantoms, Imaging; Regression Analysis; Sensitivity and Specificity | 2000 |
Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy.
Topics: Adult; Analysis of Variance; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Male; Middle Aged; Nervous System Malformations; Phosphocreatine; Reference Values | 2001 |
Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging.
Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oligodendroglioma; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease.
Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Child; Child, Preschool; Choline; Creatinine; Dipeptides; Female; Follow-Up Studies; Humans; Infant; Inositol; Lactates; Leukodystrophy, Globoid Cell; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Parietal Lobe; Phosphocreatine | 2003 |
Brainstem metabolites in multiple system atrophy of cerebellar type: 3.0-T magnetic resonance spectroscopy study.
Topics: Aged; Aspartic Acid; Biomarkers; Choline; Creatinine; Dipeptides; Feasibility Studies; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Medulla Oblongata; Middle Aged; Multiple System Atrophy; Pons; Protons; Severity of Illness Index | 2011 |
Metabolic abnormalities in pain-processing regions of patients with fibromyalgia: a 3T MR spectroscopy study.
Topics: Adult; Aspartic Acid; Choline; Chronic Pain; Creatinine; Dipeptides; Female; Fibromyalgia; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Thalamus | 2011 |
34 other study(ies) available for isospaglumic acid and choline
Article | Year |
---|---|
On the use of two-dimensional-J NMR measurements for in vivo proton MRS: measurement of homonuclear decoupled spectra without the need for short echo times.
Topics: Animals; Brain Chemistry; Choline; Creatine; Dipeptides; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Rats; Rats, Wistar | 1995 |
Relative concentrations of proton MR visible neurochemicals in gray and white matter in human brain.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Dipeptides; Female; Humans; Magnetic Resonance Spectroscopy; Male; Neuropeptides; Phosphocreatine | 1995 |
Absolute concentrations of metabolites in the adult human brain in vivo: quantification of localized proton MR spectra.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Dipeptides; Humans; Inositol; Magnetic Resonance Spectroscopy; Phosphocreatine | 1993 |
Temporal changes in proton MRS metabolites after kainic acid-induced seizures in rat brain.
Topics: Animals; Aspartic Acid; Brain; Cell Count; Choline; Creatinine; Dipeptides; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Neuropeptides; Protons; Rats; Rats, Sprague-Dawley; Seizures; Temporal Lobe | 1997 |
New approach for quantitation of short echo time in vivo 1H MR spectra of brain using AMARES.
Topics: Algorithms; Animals; Aspartic Acid; Brain; Choline; Creatine; Dipeptides; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Magnetic Resonance Imaging; Male; Rats; Rats, Wistar; Software; Time Factors | 1998 |
In vivo short echo time 1H-magnetic resonance spectroscopic imaging (MRSI) of the temporal lobes.
Topics: Adult; Aspartic Acid; Brain Mapping; Choline; Creatine; Dipeptides; Dominance, Cerebral; Energy Metabolism; Female; Fourier Analysis; Hippocampus; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Reference Values; Temporal Lobe | 2001 |
Maturation of the human fetal brain as observed by 1H MR spectroscopy.
Topics: Aspartic Acid; Brain; Choline; Creatine; Dipeptides; Female; Fetus; Gestational Age; Humans; Inositol; Magnetic Resonance Spectroscopy; Pregnancy | 2002 |
Measurement of brain glutamate using TE-averaged PRESS at 3T.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Dipeptides; Female; Fourier Analysis; Glutamic Acid; Glutamine; Humans; Image Enhancement; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropeptides; Reproducibility of Results | 2004 |
High-field localized 1H NMR spectroscopy in the anesthetized and in the awake monkey.
Topics: Anesthesia, General; Animals; Artifacts; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Dipeptides; Glutamic Acid; Glutamine; Glutathione; Hydrogen; Image Enhancement; Inositol; Lactic Acid; Macaca mulatta; Magnetic Resonance Spectroscopy; Phosphocreatine; Stereoisomerism; Taurine; Wakefulness | 2004 |
In vivo quantitative 1H MRS of cerebellum and evaluation of quantitation reproducibility by simulation of different levels of noise and spectral resolution.
Topics: Adult; Artifacts; Aspartic Acid; Body Water; Cerebellum; Choline; Creatine; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Hydrogen; Image Enhancement; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Neuropeptides | 2004 |
Quantitative proton MRS of Pelizaeus-Merzbacher disease: evidence of dys- and hypomyelination.
Topics: Aspartic Acid; Basal Ganglia; Brain; Cerebral Cortex; Child; Child, Preschool; Choline; Creatine; Dipeptides; Down-Regulation; Glutamine; Humans; Infant; Inositol; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Pelizaeus-Merzbacher Disease; Phosphocreatine; Predictive Value of Tests; Protons; Up-Regulation | 2005 |
A phase rotation scheme for achieving very short echo times with localized stimulated echo spectroscopy.
Topics: Adult; Algorithms; Brain; Choline; Creatine; Dipeptides; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging; Reference Values; Time Factors | 2005 |
Metabolite changes in early relapsing-remitting multiple sclerosis. A two year follow-up study.
Topics: Adult; Aspartic Acid; Choline; Creatine; Dipeptides; Female; Follow-Up Studies; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Statistics, Nonparametric; Time Factors | 2006 |
Magnetic resonance imaging and proton magnetic resonance spectroscopy of megalencephaly and dilated Virchow-Robin spaces.
Topics: Aspartic Acid; Brain Diseases; Child; Child, Preschool; Choline; Creatine; Dilatation, Pathologic; Dipeptides; Female; Humans; Infant; Infant, Newborn; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Organ Size; Phosphocreatine | 2006 |
Metabolic analysis of mouse brains that have compromised iron storage.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Choline; Dipeptides; Ferritins; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Iron Metabolism Disorders; Magnetic Resonance Spectroscopy; Mice; Neostriatum; Principal Component Analysis | 2006 |
Carbamazepine treatment recovered low N-acetylaspartate+N-acetylaspartylglutamate (tNAA) levels in the megencephaly mouse BALB/cByJ-Kv1.1(mceph/mceph).
Topics: Amino Acids; Anesthesia; Animals; Aspartic Acid; Brain; Carbamazepine; Choline; Data Interpretation, Statistical; Dipeptides; Female; Kv1.1 Potassium Channel; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Sex Characteristics | 2007 |
1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG.
Topics: Adult; Aspartic Acid; Biomarkers; Brain Mapping; Choline; Creatine; Dipeptides; Electroencephalography; Epilepsy, Temporal Lobe; Female; Functional Laterality; Glutamine; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Monitoring, Physiologic; Seizures; Severity of Illness Index; Temporal Lobe; Videotape Recording | 2007 |
Long and short echo time proton magnetic resonance spectroscopic imaging of the healthy aging brain.
Topics: Aged; Aged, 80 and over; Aging; Artifacts; Aspartic Acid; Brain; Choline; Creatine; Dipeptides; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons | 2007 |
Regional apparent metabolite concentrations in young adult brain measured by (1)H MR spectroscopy at 3 Tesla.
Topics: Adult; Age Factors; Aspartic Acid; Brain Chemistry; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male | 2008 |
Reduced parietooccipital white matter glutamine measured by proton magnetic resonance spectroscopy in treated graves' disease patients.
Topics: Adult; Aspartic Acid; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Graves Disease; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Parietal Lobe; Prospective Studies | 2008 |
The effect of epileptic seizures on proton MRS visible neurochemical concentrations.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Data Interpretation, Statistical; Dipeptides; Female; Glutamic Acid; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Protons; Seizures | 2008 |
Evidence for neuroinflammation and neuroprotection in HCV infection-associated encephalopathy.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Mapping; Case-Control Studies; Choline; Cognition Disorders; Creatine; Dipeptides; Fatigue; Female; Hepatic Encephalopathy; Hepatitis C; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Psychometrics; Severity of Illness Index | 2011 |
Correlation of findings in advanced MRI techniques with global severity scales in patients with Parkinson disease.
Topics: Aged; Brain; Choline; Corpus Striatum; Creatine; Diffusion Tensor Imaging; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Parkinson Disease; Severity of Illness Index; Substantia Nigra | 2011 |
Proton magnetic resonance spectroscopy and thought disorder in childhood schizophrenia.
Topics: Adolescent; Analysis of Variance; Aspartic Acid; Brain; Child; Choline; Cognition Disorders; Creatine; Dipeptides; Female; Humans; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Phosphocreatine; Protons; Psychiatric Status Rating Scales; Schizophrenia, Childhood; Statistics, Nonparametric | 2011 |
Metabolite detection of pancreatic carcinoma by in vivo proton MR spectroscopy at 3T: initial results.
Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Choline; Dipeptides; Fatty Acids, Unsaturated; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pancreatic Neoplasms; Software | 2012 |
Effects of intensive cognitive-behavioral therapy on cingulate neurochemistry in obsessive-compulsive disorder.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Cognitive Behavioral Therapy; Dipeptides; Follow-Up Studies; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurochemistry; Obsessive-Compulsive Disorder; Pilot Projects; Severity of Illness Index | 2013 |
Do reductions in brain N-acetylaspartate levels contribute to the etiology of some neuropsychiatric disorders?
Topics: Acetyltransferases; Analysis of Variance; Animals; Aspartic Acid; Brain; Choline; Chromatography, High Pressure Liquid; Dipeptides; Dopamine Agents; Exploratory Behavior; Gene Expression Regulation; Locomotion; Magnetic Resonance Spectroscopy; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout | 2013 |
Application of proton magnetic resonance spectroscopy on substantia nigra metabolites in Parkinson's disease.
Topics: Adult; Aged; Choline; Creatine; Dipeptides; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Parkinson Disease; Protons; Substantia Nigra | 2014 |
Measurement of regional variation of GABA in the human brain by optimized point-resolved spectroscopy at 7 T in vivo.
Topics: Adult; Cerebral Cortex; Choline; Computer Simulation; Creatine; Dipeptides; Feasibility Studies; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glutathione; Humans; Male; Occipital Lobe; Phantoms, Imaging; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Protons; White Matter; Young Adult | 2014 |
Cuprizone-induced demyelination and demyelination-associated inflammation result in different proton magnetic resonance metabolite spectra.
Topics: Animals; Aspartic Acid; Brain Chemistry; Choline; Creatine; Cuprizone; Demyelinating Diseases; Dipeptides; Disease Models, Animal; Female; Gliosis; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Neuroimaging; Oligodendroglia; Phosphocreatine; Proton Magnetic Resonance Spectroscopy | 2015 |
Proton magnetic resonance spectroscopy and outcome in term neonates with chorioamnionitis.
Topics: Basal Ganglia; Brain; Choline; Chorioamnionitis; Creatine; Dipeptides; Female; Healthy Volunteers; Humans; Infant; Infant, Newborn; Inflammation; Lactic Acid; Male; Multivariate Analysis; Neurodevelopmental Disorders; Neuroimaging; Pregnancy; Proton Magnetic Resonance Spectroscopy; Regression Analysis; Term Birth | 2015 |
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla.
Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Inositol; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia | 2016 |
Case control study: magnetic resonance spectroscopy of brain in HIV infected patients.
Topics: Adult; Aspartic Acid; Basal Ganglia; Case-Control Studies; Choline; Creatine; Dipeptides; Female; Frontal Lobe; Glutamic Acid; Glutamine; HIV Infections; Humans; Inositol; Lipid Metabolism; Macromolecular Substances; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Proton Magnetic Resonance Spectroscopy; White Matter | 2016 |
The impact of acute and short-term methamphetamine abstinence on brain metabolites: A proton magnetic resonance spectroscopy chemical shift imaging study.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Brain; Choline; Creatine; Dipeptides; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Male; Methamphetamine; Neurons; Proton Magnetic Resonance Spectroscopy; Young Adult | 2018 |