isospaglumic acid has been researched along with 2-amino-5-phosphonovalerate in 6 studies
| Studies (isospaglumic acid) | Trials (isospaglumic acid) | Recent Studies (post-2010) (isospaglumic acid) | Studies (2-amino-5-phosphonovalerate) | Trials (2-amino-5-phosphonovalerate) | Recent Studies (post-2010) (2-amino-5-phosphonovalerate) |
|---|---|---|---|---|---|
| 469 | 31 | 116 | 4,393 | 1 | 539 |
| Protein | Taxonomy | isospaglumic acid (IC50) | 2-amino-5-phosphonovalerate (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.29 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sekiguchi, M; Wada, K; Wenthold, RJ | 1 |
| Trombley, PQ; Westbrook, GL | 1 |
| Barkai, E; Greene, RW; Grunze, HC; Hasselmo, ME; Hearn, EF; McCarley, RW; Rainnie, DG | 1 |
| Bruno, V; Fiore, L; Nicoletti, F; Wroblewska, B; Wroblewski, JT | 1 |
| Manahan-Vaughan, D; Pöschel, B | 1 |
| Bergeron, R; Coyle, JT; Frangioni, JV; Greene, RW; Imamura, Y | 1 |
6 other study(ies) available for isospaglumic acid and 2-amino-5-phosphonovalerate
| Article | Year |
|---|---|
N-acetylaspartylglutamate acts as an agonist upon homomeric NMDA receptor (NMDAR1) expressed in Xenopus oocytes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cloning, Molecular; Dipeptides; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Oocytes; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Transcription, Genetic; Xenopus laevis | 1992 |
Excitatory synaptic transmission in cultures of rat olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cells, Cultured; Dipeptides; Electrophysiology; Evoked Potentials; Neurons; Olfactory Bulb; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1990 |
NMDA-dependent modulation of CA1 local circuit inhibition.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dipeptides; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Female; Hippocampus; Histamine H1 Antagonists; Long-Term Potentiation; Male; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Neural Inhibition; Phencyclidine; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Synaptic Transmission | 1996 |
Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Cyclopropanes; Dipeptides; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Receptors, Metabotropic Glutamate | 1998 |
Group II mGluR-induced long term depression in the dentate gyrus in vivo is NMDA receptor-independent and does not require protein synthesis.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Anisomycin; Calcium Channel Blockers; Dentate Gyrus; Dipeptides; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Functional Laterality; Glycine; Long-Term Synaptic Depression; Male; Neuroprotective Agents; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors; Verapamil | 2005 |
Endogenous N-acetylaspartylglutamate reduced NMDA receptor-dependent current neurotransmission in the CA1 area of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antibodies; Chemokine CXCL6; Chemokines, CXC; Dipeptides; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Membrane Potentials; Organophosphorus Compounds; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate | 2007 |