isosorbide dinitrate has been researched along with thromboxane b2 in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (61.11) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Drummer, C; Gerzer, R; Heim, JM; Karrenbrock, B; Valta-Seufzer, U | 1 |
| Bernini, W; De Caterina, R; Giannessi, D; Lazzerini, G; Lombardi, M; Mazzone, A; Moscarelli, E; Weiss, M | 1 |
| Brunelli, C; Caponnetto, S; Galassi, AR; Hackett, D; Ianetti, M; Lipkin, D; Maseri, A; Patrono, C; Spallarossa, P; Vejar, M | 1 |
| Bernini, W; De Caterina, R; Giannessi, D; Mazzone, A | 2 |
| Bernini, W; De Caterina, R; Giannessi, D; Lazzerini, G; Lombardi, M; Mazzone, A | 1 |
| Berenger, FP; Cano, JP; Rolland, PH | 1 |
| Cannizzaro, S; Davì, G; Giubilato, A; Mattina, A; Novo, S; Strano, A | 1 |
| De Caterina, R; Dorso, CR; Tack-Goldman, K; Weksler, BB | 1 |
| Bory, M; Cano, JP; Gueydon, E; Juhan, I; Leca, F; Rolland, PH; Sainsous, J; Serradimigni, A | 1 |
| Bernini, W; Chierchia, S; Crea, F; De Caterina, R; Gazzetti, P; Giannessi, D; L'Abbate, A | 2 |
| Bernini, W; Chierchia, S; Crea, F; De Caterina, R; Distante, A; Gazzetti, P; Giannessi, D; L'Abbate, A | 2 |
| Andersson, A; Hjemdahl, P; Wallén, NH | 1 |
| Denison, FC; Kelly, RW; Ledingham, MA; Norman, JE; Young, A | 1 |
| del Soldato, P; Fiorucci, S; Lechi, A; Mencarelli, A; Meneguzzi, A; Minuz, P; Morelli, A | 1 |
| Berti, F; Brini, AT; Clement, MG; De Gennaro Colonna, V; Manfredi, B; Polvani, G; Rossoni, G | 1 |
7 trial(s) available for isosorbide dinitrate and thromboxane b2
| Article | Year |
|---|---|
Comparison of anti-platelet properties of molsidomine, isosorbide-5-mononitrate and placebo in healthy volunteers.
Topics: Adult; Bleeding Time; Cyclic GMP; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isosorbide Dinitrate; Male; Molsidomine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Random Allocation; Reference Values; Thromboxane B2 | 1991 |
Inhibition of platelet function during in vivo infusion of isosorbide mononitrates: relationship between plasma drug concentration and hemodynamic effects.
Topics: Coronary Disease; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2 | 1990 |
Comparison of low-dose aspirin and coronary vasodilators in acute unstable angina.
Topics: Angina Pectoris; Angina, Unstable; Aspirin; Diltiazem; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Platelet Aggregation; Randomized Controlled Trials as Topic; Thromboxane A2; Thromboxane B2 | 1990 |
In vivo actions of organic nitrates on platelet function in humans.
Topics: Dose-Response Relationship, Drug; Epoprostenol; Humans; Isosorbide Dinitrate; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Vasodilator Agents | 1989 |
Enhanced platelet sensitivity to prostacyclin after isosorbide-5-mononitrate in patients with stable angina pectoris.
Topics: Adult; Angina Pectoris; Blood Platelets; Epoprostenol; Female; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Middle Aged; Platelet Aggregation; Thromboxane B2 | 1986 |
Effects of treatment with oral isosorbide dinitrate on platelet function in vivo; a double-blind placebo-controlled study in patients with stable angina pectoris.
Topics: Administration, Oral; Aged; Angina Pectoris; beta-Thromboglobulin; Blood Platelets; Creatinine; Cross-Over Studies; Double-Blind Method; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Patient Compliance; Platelet Aggregation; Thromboxane B2 | 1994 |
Nitric oxide donors stimulate prostaglandin F(2alpha) and inhibit thromboxane B(2) production in the human cervix during the first trimester of pregnancy.
Topics: Base Sequence; Cervical Ripening; Cervix Uteri; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines; Dinoprost; DNA Primers; Female; Humans; Immunohistochemistry; Isoenzymes; Isosorbide Dinitrate; Membrane Proteins; Nitric Oxide Donors; Pregnancy; Pregnancy Trimester, First; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Reverse Transcriptase Polymerase Chain Reaction; Thromboxane B2 | 1999 |
11 other study(ies) available for isosorbide dinitrate and thromboxane b2
| Article | Year |
|---|---|
Mechanisms for the in vivo antiplatelet effects of isosorbide dinitrate.
Topics: Adult; Epoprostenol; Female; Humans; Iloprost; In Vitro Techniques; Isosorbide Dinitrate; Male; Middle Aged; Platelet Aggregation Inhibitors; Thromboxane B2 | 1988 |
In vitro evidence of an endothelial cell-dependent antiplatelet activity for isosorbide dinitrate, but not for its 2- and 5-mononitrate metabolites.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Cell Extracts; Cells, Cultured; Dinoprostone; Endothelium; Female; Humans; Isosorbide Dinitrate; Male; Platelet Aggregation; Prostaglandins E; Thromboxane B2; Tissue Extracts | 1987 |
Organic nitrates: direct antiplatelet effects and synergism with prostacyclin. Antiplatelet effects of organic nitrates.
Topics: Adult; Blood Platelets; Drug Synergism; Epoprostenol; Female; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Nitrates; Platelet Aggregation; Thromboxane B2 | 1988 |
Nitrates and endothelial prostacyclin production: studies in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Blood Vessels; Cells, Cultured; Endothelium; Epoprostenol; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Thromboxane B2; Vasodilator Agents | 1985 |
Evidence for isosorbide dinitrate (ISDN) promoting effect on prostacyclin release by the lung and prostacyclin implication in ISDN-induced inhibition of platelet aggregation in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Aged; Coronary Disease; Dinoprost; Dinoprostone; Eicosanoic Acids; Epoprostenol; Humans; Isosorbide Dinitrate; Lung; Male; Middle Aged; Platelet Aggregation; Prostaglandins E; Prostaglandins F; Thromboxane B2 | 1984 |
Inhibition of platelet function by injectable isosorbide dinitrate.
Topics: Adenosine Diphosphate; Adult; Angina Pectoris; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Epinephrine; Female; Heart Rate; Humans; In Vitro Techniques; Infusions, Parenteral; Isosorbide Dinitrate; Male; Middle Aged; Platelet Aggregation; Thromboxane B2 | 1984 |
Antiplatelet effects of isosorbide dinitrate in man.
Topics: Adult; Female; Hemodynamics; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Middle Aged; Platelet Aggregation; Thromboxane B2 | 1983 |
[Effects of isosorbide dinitrate on platelet aggregation and production of thromboxane B2].
Topics: Blood Platelets; In Vitro Techniques; Isosorbide Dinitrate; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1982 |
[Effect of isosorbide dinitrate on platelet aggregation and production of thromboxane B2].
Topics: Adenosine Diphosphate; Blood Platelets; Epinephrine; Humans; In Vitro Techniques; Isosorbide Dinitrate; Platelet Aggregation; Thromboxane B2 | 1982 |
NCX-4016 (NO-aspirin) inhibits lipopolysaccharide-induced tissue factor expression in vivo: role of nitric oxide.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cyclooxygenase 2; Cysteine Proteinase Inhibitors; Drug Administration Schedule; Flow Cytometry; Gastric Mucosa; Interleukin-1; Isoenzymes; Isosorbide Dinitrate; Male; Monocytes; Nitric Oxide; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thromboplastin; Thromboxane B2; Tumor Necrosis Factor-alpha | 2002 |
Nitric oxide and prostacyclin pathways: an integrated mechanism that limits myocardial infarction progression in anaesthetized rats.
Topics: Animals; Arginine; Arrhythmias, Cardiac; Cardiotonic Agents; Creatine Kinase; Epoprostenol; Isosorbide Dinitrate; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Naproxen; Nitric Oxide; Peroxidase; Polydeoxyribonucleotides; Random Allocation; Rats; Rats, Wistar; Thromboxane B2 | 2006 |