isosorbide dinitrate has been researched along with pentaerythritol tetranitrate in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (55.56) | 18.7374 |
| 1990's | 11 (17.46) | 18.2507 |
| 2000's | 14 (22.22) | 29.6817 |
| 2010's | 3 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aletto, C; Allegri, M; Falcone, M; Gabasio, C; Giordano, MP; Guasone, V; Roncarolo, PL | 1 |
| Conti, G; Del Guercio, R; Esposito, C; Leone, C | 1 |
| Romankiewicz, JA | 1 |
| Poprawski, K | 2 |
| Krantz, JC; Leake, CD | 1 |
| Needleman, P | 1 |
| Reichek, N | 1 |
| Di Prisco, AU; Mora, A; Soro, A; Vaccari, GL | 1 |
| Baky, SH; Lee, RJ | 1 |
| Dück, KD; Richard, F | 1 |
| Assmann, I; Dueck, KD | 1 |
| Engelmann, L; Frömmel, H; Kucher, A; Wetzler, G | 1 |
| Hashimoto, H; Ito, T; Nakagawa, H; Ogawa, K; Okumura, K; Satake, T | 1 |
| Martsevich, SIu; Metelitsa, VI | 1 |
| Fink, GB; Stipe, AA | 1 |
| Hastings, SG | 1 |
| Blum, SW; Hefner, MA; Howe, BB; Quinn, JB; Winbury, MM | 1 |
| Blehm, DJ; Harkey, AB; Johnson, EM; Needleman, P | 1 |
| Kaltenbach, M; Schellhorn, W; Tiedemann, I | 1 |
| Bleifeld, W | 1 |
| Russek, HI | 3 |
| Wendkos, MH | 1 |
| Dalvi, CP; Datey, KK | 1 |
| Both, A | 1 |
| Nager, F | 1 |
| Goff, EU; Yu, WC | 1 |
| Gelber, L; Papas, AN | 1 |
| Olsen, CS; Scroggins, HS | 1 |
| Halawa, B | 1 |
| Baligadoo, S; Chiche, P | 1 |
| Arnoux, F; Bory, M; Clavier, P; Djiane, P; Egre, A; Serradimigni, A | 1 |
| Aldor, E; Gaul, G | 1 |
| Kojda, G; Kottenberg, E; Noack, E; Schnaith, EM; Stein, D | 1 |
| Agabiti-Rosei, E; Motolese, M; Savonitto, S | 1 |
| Kojda, G; Noack, E | 1 |
| Thadani, U | 1 |
| Snape, JR; White, GF | 1 |
| Kojda, G; Kottenberg, K; Nix, P; Noack, E; Piper, HM; Schlüter, KD | 1 |
| Hacker, A; Hüsgen, B; Kojda, G; Kottenberg, E; Noack, E; Perings, D; Schnaith, EM | 1 |
| Heintz, B; Kirsten, D; Kirsten, R; Nelson, K | 1 |
| de la Motte, S; Harrison, F; Pfaffenrath, V; Rüthning, C | 1 |
| Abate, A; Oberle, S; Schröder, H; Schwartz, P | 1 |
| Jedrzejczyk, B; Kośmicki, M; Kowalik, I; Sadowski, Z | 1 |
| Schneider, CA | 1 |
| Frölich, JC; Gutzki, FM; Keimer, R; Stutzer, FK; Troost, R; Tsikas, D | 1 |
| Abate, A; Dennery, PA; Grosser, N; Hemmerle, A; Oberle, S; Schneider, HT; Schröder, H; Stalleicken, D; Vreman, HJ | 1 |
| Jin, JZ; Kong, J; Li, DY; Tian, Z; Wang, MF; Wang, W; Wu, SD; Zhang, ZH | 1 |
| Nungester, WJ; Paradise, LJ | 1 |
| Bauersachs, J; Daiber, A; Ertl, G; Fraccarollo, D; Munzel, T; Schultheiss, M; Thum, S; Thum, T; Wenzel, P | 1 |
| Di Stolfo, G; Dragoni, S; Gori, T; Kleinert, H; Lisi, M; Parker, JD; Pautz, A | 1 |
| Giani, G; Haastert, B; Icks, A; Rathmann, W; Schröder-Bernhardi, D | 1 |
| Richartz, BM; Schneider, HT; Silber, S | 1 |
| Bas, M; Dao, VT; Kojda, G; Oppermann, M; Suvorava, T | 1 |
| Münzel, T | 1 |
| Daiber, A; Gori, T | 1 |
| Ahimastos, AA; Duffy, SJ; Formosa, MF; Henstridge, DC; Kingwell, BA; Thompson, BR | 1 |
| Bauersachs, J; Ertl, G; Thum, T; Wiebking, V | 1 |
| Bollmann, F; Daiber, A; Gori, T; Hausding, M; Heeren, T; Kleinert, H; Knorr, M; Münzel, T; Oelze, M; Otto, C; Pautz, A; Reifenberg, K; Schuhmacher, S; Schulz, E; Steven, S; Wenzel, P | 1 |
| Erbay, AR; Gür, M; Senen, K; Sivri, N; Tekin, G; Yalta, K; Yetkin, E | 1 |
8 review(s) available for isosorbide dinitrate and pentaerythritol tetranitrate
| Article | Year |
|---|---|
Organic nitrate metabolism.
Topics: Animals; Biodegradation, Environmental; Dogs; Guinea Pigs; Humans; In Vitro Techniques; Isosorbide Dinitrate; Mice; Nitrates; Nitroglycerin; Oxidoreductases; Pentaerythritol Tetranitrate; Propylene Glycols; Rats; Time Factors | 1976 |
[Drug treatment of chronic coronary disease].
Topics: Chronic Disease; Coronary Circulation; Coronary Disease; Humans; Isosorbide Dinitrate; Myocardium; Nitroglycerin; Oxygen Consumption; Pentaerythritol Tetranitrate; Propranolol; Vasodilator Agents | 1980 |
Nitrate therapy and the development of tolerance.
Topics: Angina Pectoris; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilator Agents | 1993 |
Microbial cleavage of nitrate esters: defusing the environment.
Topics: Biodegradation, Environmental; Collodion; Environmental Microbiology; Environmental Pollutants; Ethylene Glycols; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate | 1993 |
Clinical pharmacokinetics of vasodilators. Part II.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Alprostadil; Amrinone; Carbazoles; Carvedilol; Enoximone; Female; Humans; Iloprost; Imidazoles; Indoramin; Isosorbide Dinitrate; Labetalol; Milrinone; Molsidomine; Nitroglycerin; Nitroprusside; Oxyfedrine; Pentaerythritol Tetranitrate; Phosphodiesterase Inhibitors; Piperazines; Prazosin; Pregnancy; Propanolamines; Pyridones; Theophylline; Trapidil; Vasodilator Agents | 1998 |
[PETN: long acting nitrate with tolerance devoiding properties and innovative potential].
Topics: Angina Pectoris; Animals; Confidence Intervals; Disease Models, Animal; Drug Tolerance; Endothelium, Vascular; Headache; Humans; Isosorbide Dinitrate; Mice; Multicenter Studies as Topic; Oxidative Stress; Pentaerythritol Tetranitrate; Randomized Controlled Trials as Topic; Smoking; Time Factors; Vasodilator Agents | 2008 |
[Recent findings on nitrates: their action, bioactivation and development of tolerance].
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Coronary Disease; Drug Tolerance; Endothelium, Vascular; Guanylate Cyclase; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Oxidative Stress; Pentaerythritol Tetranitrate; Reactive Oxygen Species; Vasodilation; Vasodilator Agents | 2008 |
Non-hemodynamic effects of organic nitrates and the distinctive characteristics of pentaerithrityl tetranitrate.
Topics: Animals; Drug Administration Schedule; Drug Tolerance; Heart Diseases; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Oxidative Stress; Pentaerythritol Tetranitrate; Reactive Oxygen Species; Vasodilator Agents | 2009 |
21 trial(s) available for isosorbide dinitrate and pentaerythritol tetranitrate
| Article | Year |
|---|---|
[Evaluation of the therapeutic efficacy of 4 different delayed-action nitro-derivatives on S-T changes after exercise tests].
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Circulation; Delayed-Action Preparations; Drug Evaluation; Electrocardiography; Exercise Test; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Placebos | 1978 |
[Long-term nitrate therapy in coronary heart disease--loss of effect by developing tolerance].
Topics: Angina Pectoris; Coronary Disease; Dose-Response Relationship, Drug; Drug Tolerance; Electrocardiography; Exercise Test; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Long-Term Care; Male; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate | 1990 |
[Long-term effect of various nitrates in ischemic heart disease and latent heart failure].
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Female; Heart Failure; Humans; Isosorbide Dinitrate; Long-Term Care; Male; Middle Aged; Myocardial Infarction; Pentaerythritol Tetranitrate; Propylene Glycols; Pulmonary Wedge Pressure; Randomized Controlled Trials as Topic; Vasodilator Agents | 1989 |
[Development and status of nitrate therapy in East Germany].
Topics: Angina Pectoris; Delayed-Action Preparations; Dose-Response Relationship, Drug; Germany, East; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Propylene Glycols; Vasodilator Agents | 1989 |
Prophylactic therapy of angina pectoris with organic nitrates: relationship of drug efficacy and clinical experimental design.
Topics: Angina Pectoris; Clinical Trials as Topic; Erythrityl Tetranitrate; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Placebos; Research Design; Time Factors | 1973 |
[The effect of five different long-acting nitroglycerine derivatives on angina pectoris].
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Electrocardiography; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Phenobarbital; Physical Exertion; Placebos; Vasodilator Agents | 1972 |
New dimension in angina pectoris therapy.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Drug Synergism; Electrocardiography; Exercise Test; Female; Furans; Heart Rate; Humans; Ischemia; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitrates; Pentaerythritol Tetranitrate; Propranolol; Tachycardia | 1969 |
The therapeutic role of coronary vasodilators: glyceryl trinitrate, isosorbide dinitrate, and pentaerythritol tetranitrate.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Electrocardiography; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrites; Nitroglycerin; Pentaerythritol Tetranitrate; Physical Exertion | 1966 |
Stress tests and the evaluation of anti-anginal drugs.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Electrocardiography; Erythrityl Tetranitrate; Evaluation Studies as Topic; Exercise Test; Heart; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate | 1967 |
Anti anginal drugs, their evaluation by double blind trial.
Topics: Adult; Aged; Angina Pectoris; Erythrityl Tetranitrate; Female; Humans; Isosorbide Dinitrate; Male; Mannitol; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Placebos; Vasodilator Agents; Verapamil | 1970 |
[Comparative study of three oral nitrate derivatives. A hemodynamic assessment in 10 patients with chronic heart failure (author's transl)].
Topics: Administration, Oral; Adult; Blood Pressure; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Pulmonary Artery | 1980 |
[Pulmonary artery pressure measurement for assessment of bioavailability of isosorbide dinitrate and pentaerythritol tetranitrate (author's transl)].
Topics: Adult; Biological Availability; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Humans; Isosorbide Dinitrate; Male; Meprobamate; Middle Aged; Pentaerythritol Tetranitrate; Pulmonary Artery; Pulmonary Circulation | 1980 |
Antianginal effect of transdermal nitroglycerin and oral nitrates given for 24 hours a day in 2,456 patients with stable angina pectoris. The Italian Multicenter Study.
Topics: Administration, Cutaneous; Administration, Oral; Aged; Angina Pectoris; Chronic Disease; Circadian Rhythm; Drug Tolerance; Female; Humans; Isosorbide Dinitrate; Italy; Male; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilator Agents | 1995 |
[Actions of pentaerithritol tetranitrate, isosorbide mononitrate and placebo on headache and ability to work of healthy subjects].
Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Headache; Humans; Isosorbide Dinitrate; Male; Pentaerythritol Tetranitrate; Vasodilator Agents; Work | 1998 |
[Comparative evaluation of the clinical effectiveness and the adverse effects of three different forms of nitrates in high oral doses in patients with stable angina pectoris].
Topics: Angina Pectoris; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Treatment Outcome; Vasodilator Agents | 2002 |
Lack of oxidative stress during sustained therapy with isosorbide dinitrate and pentaerythrityl tetranitrate in healthy humans: a randomized, double-blind crossover study.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Humans; Isosorbide Dinitrate; Male; Nitrites; Oxidative Stress; Pentaerythritol Tetranitrate | 2003 |
Nitroester drug's effects and their antagonistic effects against morphine on human sphincter of Oddi motility.
Topics: Adult; Aged; Analgesics, Opioid; Drug Interactions; Female; Gastrointestinal Motility; Humans; Isosorbide Dinitrate; Male; Middle Aged; Morphine; Nitroglycerin; Pentaerythritol Tetranitrate; Sphincter of Oddi; Vasodilator Agents | 2005 |
Pentaerythrityl tetranitrate and nitroglycerin, but not isosorbide mononitrate, prevent endothelial dysfunction induced by ischemia and reperfusion.
Topics: Adult; Double-Blind Method; Endothelium, Vascular; Humans; Ischemic Preconditioning; Isosorbide Dinitrate; Male; Nitroglycerin; Pentaerythritol Tetranitrate; Reperfusion Injury; Vasodilator Agents | 2007 |
Oral nitrate therapy does not affect glucose metabolism in healthy men.
Topics: Adult; Blood Glucose; Cyclic GMP; Delayed-Action Preparations; Glucose Tolerance Test; Humans; Infusions, Intravenous; Insulin; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Pentaerythritol Tetranitrate; Pulmonary Circulation | 2009 |
Organic nitrates differentially modulate circulating endothelial progenitor cells and endothelial function in patients with symptomatic coronary artery disease.
Topics: Adult; Aged; Coronary Artery Disease; Endothelium, Vascular; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide Donors; Pentaerythritol Tetranitrate; Plethysmography; Stem Cells | 2011 |
Headache response to nitrate in patients with coronary artery disease and systolic heart failure.
Topics: Aged; Coronary Artery Disease; Female; Headache; Heart Failure, Systolic; Humans; Isosorbide Dinitrate; Male; Middle Aged; Pentaerythritol Tetranitrate; Vasodilator Agents | 2012 |
34 other study(ies) available for isosorbide dinitrate and pentaerythritol tetranitrate
| Article | Year |
|---|---|
[Response of the arteriolar circulation evaluated by means of photoplethysmography after nitroderivatives].
Topics: Arterial Occlusive Diseases; Arteries; Arterioles; Blood Circulation; Erythrityl Tetranitrate; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Plethysmography | 1977 |
Pharmacology update: anti-anginal agents.
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Nitroglycerin; Pentaerythritol Tetranitrate | 1979 |
[Effectiveness of isosorbide dinitrate and pentaerythritol tetranitrate by means of acute determination of the coronary reserve on cycloergometer in patients with stable angina pectoris].
Topics: Adult; Angina Pectoris; Coronary Circulation; Exercise Test; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Pentaerythritol Tetranitrate | 1979 |
[Effectiveness of oral isosorbide dinitrate and pentaerythritol tetranitrate in the light of long-term determinations of coronary reserve on cycloergometer in patients with stable angina pectoris].
Topics: Administration, Oral; Adult; Angina Pectoris; Coronary Circulation; Exercise Test; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Pentaerythritol Tetranitrate | 1979 |
The gastrointestinal absorption of organic nitrates.
Topics: Administration, Oral; Animals; Delayed-Action Preparations; Dogs; Humans; Intestinal Absorption; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Rabbits; Rats; Tablets | 1975 |
Long-acting nitrates in the treatment of angina pectoris.
Topics: Angina Pectoris; Delayed-Action Preparations; Erythrityl Tetranitrate; Hemodynamics; Humans; Isosorbide Dinitrate; Methods; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Physical Exertion; Substance-Related Disorders | 1976 |
[Treatment of coronary insufficiency with a combination of 2 nitro-derivatives. Controlled pluricentric clinical trial].
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Drug Combinations; Drug Evaluation; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Pentaerythritol Tetranitrate | 1975 |
Effects of several antianginal agents on pacing-induced S-T Segment depression in the atherosclerotic rabbit.
Topics: Angina Pectoris; Animals; Arteriosclerosis; Autonomic Agents; Cardiac Catheterization; Chromonar; Depression, Chemical; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Heart Atria; Heart Rate; Isosorbide Dinitrate; Male; Pacemaker, Artificial; Papaverine; Pentaerythritol Tetranitrate; Propranolol; Rabbits; Vasodilator Agents | 1975 |
Effects of atrial natriuretic polypeptide and organic nitrates on levels of relaxation and cyclic nucleotide of canine coronary artery with and without endothelial injury.
Topics: Animals; Atrial Natriuretic Factor; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dogs; Endothelium, Vascular; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilation | 1988 |
[Efficacy of erynite in angina pectoris].
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Pentaerythritol Tetranitrate | 1987 |
Bioavailability studies of nitrates in the dog.
Topics: Administration, Oral; Animals; Biopharmaceutics; Blood Pressure; Cardiovascular System; Delayed-Action Preparations; Dogs; Dose-Response Relationship, Radiation; Heart; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Oxygen Consumption; Pentaerythritol Tetranitrate; Pulse; Vasodilator Agents | 1973 |
Pharmacologic and biochemical evaluation of organic nitrates: attempted correlation of activities.
Topics: Animals; Chemistry, Organic; Dogs; Electron Transport; Erythrityl Tetranitrate; Evaluation Studies as Topic; Heart; In Vitro Techniques; Isosorbide Dinitrate; Mannitol; Mitochondria, Muscle; Myocardium; NAD; Nitrates; Nitroglycerin; Organic Chemistry Phenomena; Oxidative Phosphorylation; Oxidoreductases; Pentaerythritol Tetranitrate; Rats; Vasodilator Agents | 1971 |
Clearance and metabolism of organic nitrates.
Topics: Adenosine Triphosphate; Animals; Blood; Carbon Isotopes; Erythrityl Tetranitrate; Glutathione; In Vitro Techniques; Isosorbide Dinitrate; Kinetics; Liver; Mannitol; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Rats | 1972 |
[Letter: Loss of efficacy in long-term nitrites?].
Topics: Drug Storage; Isosorbide Dinitrate; Pentaerythritol Tetranitrate; Time Factors | 1973 |
Medical perspectives of coronary artery disease.
Topics: Angina Pectoris; Anticoagulants; Coronary Disease; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Pentaerythritol Tetranitrate | 1967 |
[Therapy of primary pulmonary hypertension].
Topics: Acetylcholine; Amino Alcohols; Carbachol; Child; Diazepam; Diazoxide; Female; Humans; Hypertension, Pulmonary; Isoproterenol; Isosorbide Dinitrate; Neostigmine; Nitroglycerin; Pentaerythritol Tetranitrate; Rest; Theophylline; Tolazoline; Verapamil | 1970 |
[Conservative therapy of angina pectoris].
Topics: Acute Disease; Amyl Nitrite; Angina Pectoris; Anticoagulants; Coronary Disease; Digitalis Glycosides; Furans; Heart Failure; Humans; Hypotension, Orthostatic; Isosorbide Dinitrate; Morphine; Myocardial Infarction; Nitrates; Nitrites; Nitroglycerin; Pentaerythritol Tetranitrate; Propranolol; Rest; Sympatholytics; Syncope; Vascular Headaches | 1970 |
Determination of vasodilators and their metabolites in plasma by liquid chromatography with a nitrosyl-specific detector.
Topics: Chromatography, High Pressure Liquid; Humans; Isosorbide Dinitrate; Nitroglycerin; Pentaerythritol Tetranitrate | 1983 |
Validation of high-performance liquid chromatographic methods for analysis of sustained-release preparations containing nitroglycerin, isosorbide dinitrate, or pentaerythritol tetranitrate.
Topics: Acetonitriles; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dimethyl Sulfoxide; Isosorbide Dinitrate; Nitroglycerin; Pentaerythritol Tetranitrate | 1983 |
High-performance liquid chromatographic determination of the nitrate esters isosorbide dinitrate, pentaerythritol tetranitrate, and erythrityl tetranitrate in various tablet forms.
Topics: Chromatography, High Pressure Liquid; Erythrityl Tetranitrate; Isosorbide Dinitrate; Pentaerythritol Tetranitrate; Tablets | 1984 |
[Are nitrate compounds effective when administered orally? Results of pharmacokinetic and hemodynamic studies].
Topics: Administration, Oral; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilator Agents | 1980 |
In vivo effects of pentaerythrityl-tetranitrate and isosorbide-5-mononitrate on the development of atherosclerosis and endothelial dysfunction in cholesterol-fed rabbits.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Azo Compounds; Cholesterol, Dietary; Coloring Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Endothelium, Vascular; Female; Gas Chromatography-Mass Spectrometry; Isosorbide Dinitrate; Lipids; Muscle Relaxation; Muscle, Smooth, Vascular; Pentaerythritol Tetranitrate; Rabbits; Staining and Labeling; Vasodilator Agents | 1995 |
Effects of pentaerythrityl-tetranitrate and isosorbide-5-mononitrate in experimental atherosclerosis.
Topics: Animals; Arteriosclerosis; Cholesterol; Diet, Atherogenic; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Isosorbide Dinitrate; Nitric Oxide; Pentaerythritol Tetranitrate; Rabbits; Vasodilation | 1995 |
Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes.
Topics: Animals; Cells, Cultured; Cyclic GMP; Electric Stimulation; Heart Ventricles; Hydrazines; Isosorbide Dinitrate; Male; Myocardial Contraction; Nitrogen Oxides; Nitroglycerin; Penicillamine; Pentaerythritol Tetranitrate; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1996 |
Impairment of endothelium-dependent vasorelaxation in experimental atherosclerosis is dependent on gender.
Topics: Acetylcholine; Animals; Aorta; Arteriosclerosis; Cholesterol, Dietary; Endothelium, Vascular; Female; In Vitro Techniques; Isosorbide Dinitrate; Male; Penicillamine; Pentaerythritol Tetranitrate; Rabbits; Sex Factors; Vasodilation; Vasodilator Agents | 1998 |
The antioxidant defense protein ferritin is a novel and specific target for pentaerithrityl tetranitrate in endothelial cells.
Topics: Animals; Antioxidants; Aorta; Cells, Cultured; Cyclic GMP; Cyclic N-Oxides; Deferoxamine; Endothelium, Vascular; Ferritins; Free Radical Scavengers; Gene Expression; Guanylate Cyclase; Imidazoles; Iron Chelating Agents; Isosorbide Dinitrate; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Pentaerythritol Tetranitrate; Spermine; Swine | 1999 |
[How is antianginal therapy with pentaerythritol tetranitrate executed?].
Topics: Angina Pectoris; Animals; Delayed-Action Preparations; Drug Administration Schedule; Heart Diseases; Humans; Isosorbide Dinitrate; Pentaerythritol Tetranitrate; Time Factors; Vasodilator Agents | 2002 |
Endothelial protection by pentaerithrityl trinitrate: bilirubin and carbon monoxide as possible mediators.
Topics: Animals; Antioxidants; Bilirubin; Carbon Monoxide; Cell Survival; Cells, Cultured; Endothelium, Vascular; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Isosorbide Dinitrate; Membrane Proteins; Nitric Oxide Donors; Pentaerythritol Tetranitrate; S-Nitroso-N-Acetylpenicillamine | 2003 |
[Continuous protection against angina pectoris-like disorders. Attack prevention without a nitrate pause].
Topics: Angina Pectoris; Coronary Disease; Free Radicals; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitrates; Nitric Oxide Donors; Oxidative Stress; Pentaerythritol Tetranitrate; Time Factors; Vasodilator Agents | 2003 |
Supporting role of vasodilators in inducing regressions of the Ehrlich solid tumor.
Topics: Animals; Carcinoma, Ehrlich Tumor; Epinephrine; Isosorbide Dinitrate; Lymph Nodes; Male; Mice; Pentaerythritol Tetranitrate; Vasodilator Agents | 1967 |
Differential effects of organic nitrates on endothelial progenitor cells are determined by oxidative stress.
Topics: Animals; Blood Cells; Bone Marrow; Cell Movement; Cells, Cultured; Endothelial Cells; Humans; Isosorbide Dinitrate; Male; NADP; Nitric Oxide Donors; Oxidative Stress; Pentaerythritol Tetranitrate; Rats; Rats, Wistar; Reactive Oxygen Species; Stem Cells; Superoxides | 2007 |
Cost comparison analysis: pentaerythrithyl tetranitrate (PETN) and isosorbide dinitrate (ISDN) prescribed to diabetic patients in primary care practices in Germany.
Topics: Aged; Aged, 80 and over; Cost-Benefit Analysis; Databases, Factual; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Germany, East; Germany, West; Humans; Isosorbide Dinitrate; Male; Multivariate Analysis; Myocardial Ischemia; Pentaerythritol Tetranitrate; Practice Patterns, Physicians'; Primary Health Care; Regression Analysis; Vasodilator Agents | 2007 |
Effect of oral organic nitrates on expression and activity of vascular soluble guanylyl cyclase.
Topics: Administration, Oral; Analysis of Variance; Animals; Aorta, Thoracic; Blotting, Western; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Isosorbide Dinitrate; Lung; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Donors; Pentaerythritol Tetranitrate; Protein Subunits; Rabbits; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilator Agents | 2008 |
Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; Gene Silencing; GTP Cyclohydrolase; Heme Oxygenase-1; Isosorbide Dinitrate; Male; NADPH Oxidases; Oxidative Stress; Pentaerythritol Tetranitrate; Rats; Rats, Wistar; Reactive Oxygen Species; Vasoconstriction; Vasodilator Agents; Weight Gain; Xanthine Oxidase | 2011 |