isosorbide dinitrate has been researched along with nitroglycerin in 650 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 403 (62.00) | 18.7374 |
| 1990's | 144 (22.15) | 18.2507 |
| 2000's | 73 (11.23) | 29.6817 |
| 2010's | 26 (4.00) | 24.3611 |
| 2020's | 4 (0.62) | 2.80 |
| Authors | Studies |
|---|---|
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Daiber, A; Glusa, E; Koenig, A; Lange, K; Lehmann, J; Roegler, C | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kaltenbach, M | 3 |
| Thiede, D | 1 |
| Rivier, JL | 1 |
| Paul, O | 2 |
| Enenkel, W | 2 |
| Short, D | 2 |
| Brix, W; Hochrein, H; Lehmann, HU | 1 |
| Sowton, E | 1 |
| Bleifeld, W | 1 |
| Dacian, S; Loracher, C; Rudolph, W | 1 |
| Schrey, A | 1 |
| Brundage, BH; Chatterjee, K; Gelberg, H; Massie, B; Ports, TA; Rubin, S | 1 |
| Cohen, LS; Geha, AS; Hammond, GL; Langou, RA | 1 |
| Aletto, C; Allegri, M; Falcone, M; Gabasio, C; Giordano, MP; Guasone, V; Roncarolo, PL | 1 |
| Kimata, S | 1 |
| Baitsch, G; Bertel, O; Burkart, F; Elsässer, S; Ritz, R | 1 |
| Conti, G; Del Guercio, R; Esposito, C; Leone, C | 1 |
| Brachmann, J; Krämer, B; Kübler, W; Pelzer, D; Senges, J; Zebe, H | 1 |
| Alvaro, AB; Coulson, AH; Kattus, AA; Zohman, LR | 1 |
| Mantle, JA; Rackley, CE; Rogers, WJ; Russell, RO | 2 |
| Aroesty, JM; O'Grady, GP; Paulin, S; Weintraub, RM | 1 |
| Romankiewicz, JA | 1 |
| Leydhecker, W | 1 |
| Goch, JH | 1 |
| Gvatua, NA; Ivanova, LK; Kravtsov, VL; Shkliar, LV; Shumakov, VA | 1 |
| Bevilacqua, R; Grassi, T; Marra, S; Paolillo, V | 1 |
| Eifert, J | 1 |
| Baclet, M; Fernandez, F; Gerbaux, A; Mechmeche, R; Sprogis, W | 1 |
| Murao, S; Uchida, Y; Yoshimoto, N | 1 |
| Kobayashi, A; Ogawa, K | 1 |
| Kennedy, RD | 1 |
| Aronow, WS; Burwell, DT; Danahy, DT; Prakash, R | 1 |
| Shah, PK | 1 |
| Ogawa, T; Rose, HB; Takano, TT; Vyden, JK | 1 |
| Goldstein, RE | 1 |
| Imai, S; Katono, Y; Nakagawa, Y; Takeda, K | 1 |
| Alimurung, B; Fletcher, GF; Watt, E | 1 |
| Aronow, WS; Danahy, DT | 1 |
| Hardarson, T; Henning, H; O'Rourke, RA | 1 |
| Schröder, R | 1 |
| Preston, TA; Richtsmeier, TE | 1 |
| Chatterjee, K; Greenberg, B; Hart, R; Massie, B; Parmley, WW; Werner, J | 1 |
| De Maria, AN; Lee, G; Mason, DT | 1 |
| Burch, GE | 1 |
| Parmley, WW | 1 |
| Francis, GS; Hagan, AD | 1 |
| Abrams, J | 8 |
| Manfrin, M; Prati, PL | 1 |
| Franciosa, JA | 1 |
| Imhof, P | 1 |
| Biamino, G; Nöring, J | 1 |
| Russek, HI | 7 |
| Kattus, AA | 2 |
| Alvaro, AB; Coulson, A; Kattus, AA | 1 |
| Beck, OA; Hochrein, H; Krämer, KD; Wolf, R | 1 |
| Davidson, IW; Di Carlo, FJ; Parker, JC | 1 |
| Berger, HJ; Howe, BB; Mills, B; Winbury, MM; Winsor, T | 1 |
| Cohn, JN; Franciosa, JA; Mikulic, E | 1 |
| Mason, DT; Zelis, R | 1 |
| Krantz, JC; Leake, CD | 1 |
| Bussmann, WD | 2 |
| Mantle, JA; Rackley, CE; Ratshin, RA; Russell, RO; Willis, WH | 1 |
| Behrenbeck, DW; Hilger, HH; Niehues, B; Tauchert, M | 1 |
| Berens, SC; Bramowitz, AD; Kovick, RB; Shine, KI; Tillisch, JH | 1 |
| Cohen, MV; Kirk, ES; Sonnenblick, EH | 1 |
| Kise, MS | 1 |
| da Luz, PL; Forrester, JS | 1 |
| Matos, L | 1 |
| Goossens, AP; Hawkins, DM; Lotter, AP; Polakow, ES | 1 |
| Beck, OA; Guhl, E; Hochrein, H; Wolf, R | 1 |
| Needleman, P | 1 |
| Pascal, N | 1 |
| Reichek, N | 1 |
| Battock, DJ; Levitt, PW; Steele, PP | 1 |
| Chatterjee, K; Drew, D; Klausner, SC; Parmley, WW; Polansky, J; Zacherle, B | 1 |
| Dacian, S; Dirschinger, J; Fleck, E; Loracher, C; Rudolph, W | 1 |
| Kronik, G; Mösslacher, H; Slany, J | 1 |
| Trakhtenberg, SB | 1 |
| Mantle, JA; Moraski, RE; Rackley, CE; Rogers, WJ; Russel, RO | 1 |
| Chiche, P; Derrida, JP | 1 |
| Adelman, AG; Berman, ND; Huckell, VF; Mahon, WA; McLaughlin, PR; Morch, JE | 1 |
| Behrenbeck, DW; Hilger, HH; Tauchert, M | 1 |
| Bussmann, WD; Kaltenbach, M; Schöfer, H | 1 |
| Wagner, G | 1 |
| Blaschke, TF; Hoffman, BB; Kongpatanakul, S; Vincent, J | 1 |
| Dukhanin, AS; Khamitova, ES; Sergeev, PV; Shilo, VIu; Shimanovskiĭ, NL; Storozhakov, GI; Trepilets, VE | 1 |
| Duboc, D; Guérin, F; Weber, S | 1 |
| Folland, ED; Hartigan, P; Parisi, AF | 1 |
| Schmid, M; Yeates, RA | 1 |
| Bareiss, P; Mossard, JM; Roul, G; Sacrez, A | 1 |
| Julínek, J; Meluzín, J; Novák, M; Simek, P; Spinarová, L; Stejfa, M; Toman, J; Zeman, K | 1 |
| Ball, JG; Gruetter, CA; Morenas, M; Szarek, JL; Valentovic, MA | 1 |
| Bassan, MM; Rogel, S | 1 |
| Ageev, FT; Grigor'iants, RA; Kazeĭ, DV; Mareev, VIu; Shevliagin, SA | 1 |
| Hennig, B; Lüdecke, F; Vetter, B | 1 |
| Geppert, R; Hinsche, A; Jansen, W; Rappert, B; Tauchert, M | 1 |
| Pannier, B; Safar, M | 1 |
| Lecompte, T; Makowski, S | 1 |
| Berdeaux, A; Drieu la Rochelle, C; Giudicelli, JF; Richard, V; Roupie, E | 1 |
| Bauters, C; Bertrand, ME; Lablanche, JM; Leroy, F | 1 |
| Nathanson, JA | 1 |
| Werkö, L | 1 |
| Auclert, L; Blin, P; Guérin, C; Guérin, F; Pellois, A; Touiza, K; Weber, S | 1 |
| Thadani, U | 3 |
| Kuhn, M | 1 |
| Fernández, N; Martinez, A; Pedrote, A; Sobrino, JM | 1 |
| Heinonen, J; Hynynen, M; Muikku, O; Salmenperä, M | 1 |
| Feelisch, M; Kelm, M | 1 |
| Akhras, F; Jackson, G | 1 |
| Feelisch, M; Noack, E | 1 |
| Henry, PJ; Horowitz, JD; Louis, WJ | 2 |
| Gendel'man, AM; Lazebnik, LB; Tereshchenko, SN | 1 |
| Martynov, AI; Salnikov, SN; Vertkin, AL; Zharov, EI | 1 |
| Figg, WD; O'Quinn, SV | 1 |
| Alberti, D; Cadeddu, M; Lai, C; Lai, G; Onnis, E; Orani, E; Pirisi, R; Soro, A | 1 |
| Smirnova, IE; Uchaĭkina, LV; Vakhliaev, VD; Zolotareva, NIu | 1 |
| Barthelemy, C; Guyot-Hermann, AM; Parier, JL; Ringard, J; Ringard-Lefebvre, C | 1 |
| Anderson, KA | 1 |
| Eidsaunet, W; Erikssen, J; Myhre, E; Røde, R; Thaulow, E | 1 |
| Bassan, M | 1 |
| Anggård, E; Arvill, A; Jörgensen, E | 1 |
| Akkila, J; Lahti, T; Nissinen, A; Puska, P; Wahl, M; Wiklund, I; Wilson, A | 1 |
| Bechtold, H; Kleist, P; Wiegand, A | 1 |
| Nyberg, G | 1 |
| Holzmann, S; Kukovetz, WR | 4 |
| Iida, K | 1 |
| Kato, K; Watanabe, H | 1 |
| Baldenkov, GN; Mazaev, AV; Mukharliamov, NM; Negrescu, EV; Sazonova, LN; Tkachuk, VA | 1 |
| Alpert, JS | 1 |
| Marmor, A | 1 |
| Jonsson, UE | 1 |
| Parker, JO | 7 |
| Silber, S | 2 |
| Gulba, D; Hecker, H; Jost, S; Knop, I; Lichtlen, PR; Rafflenbeul, W; Reil, GH | 1 |
| Lebrec, D; Moreau, R | 1 |
| Dirschinger, J; Hall, D; Rudolph, W | 1 |
| Vine, DL | 1 |
| Marcus, FI | 1 |
| Bosch, J; Bru, C; Feu, F; García-Pagán, JC; Navasa, M; Rodés, J; Ruiz del Arbol, L | 1 |
| Ahlner, J; Axelsson, KL; Torfgård, K | 2 |
| Bennett, BM; Booth, BP; Brien, JF; Elliott, DA; Marks, GS; McCans, JL; Nakatsu, K | 1 |
| Alibekov, SD; Belova, LF; Belozerova, OP; Ivanov, AA; Rusakova, KA; Sakovich, GS; Sokolov, SIa; Trumpe, TE | 1 |
| Bennett, BM; McDonald, BJ | 1 |
| Noack, E | 1 |
| Dück, KD; Richard, F | 1 |
| Flatmark, T; Grønberg, M; Husebye, ES; Terland, O | 1 |
| Karaki, H; Murakami, K; Urakawa, N | 1 |
| Kuromaru, O; Sakai, K | 2 |
| Aldershvile, J; Klarlund, K; Svendsen, JH; Waldorff, S | 1 |
| Reynolds, GW; Richmond, A; Silke, B; Taylor, SH; Verma, SP | 1 |
| Hisano, K; Inoue, T; Mohri, M; Nakamura, M; Tomoike, H | 1 |
| Ball, JG; Bosserman, MK; Childers, CE; Gruetter, CA; Lemke, SM; Valentovic, MA | 1 |
| Heaton, JP | 1 |
| DasGupta, P; Hughes, LO; Jain, D; Lahiri, A; Raftery, EB | 1 |
| Johansson, BW | 1 |
| Bayeric, A; Dirschinger, J; Hall, D; Reiniger, G; Rudolph, W | 1 |
| Herpai, Z; Moser, G | 1 |
| Akhras, F; Chambers, J; Jackson, G; Jefferies, S | 1 |
| Ake, H; Arina, R; Emanuelsson, H; Kristi, M | 1 |
| Kots, IaI; Solonovich, TG | 1 |
| Silke, B; Taylor, SH; Verma, SP | 1 |
| Engelmann, L; Frömmel, H; Kucher, A; Wetzler, G | 1 |
| Burk, RF; Haap, M; Hill, KE; Hunt, RW; Konz, KH; Ziegler, DM | 1 |
| Döbrönte, Z | 1 |
| Penkov, N; Sirakova, V | 1 |
| Brien, JF; Marks, GS; McLaughlin, BE; Nakatsu, K; Slack, CJ | 2 |
| Lekkerkerker, JF | 1 |
| Barthelemy, C; Guyot-Hermann, AM; Lefebvre, C; Parier, JL; Ringard, J | 2 |
| Davis, ME; Feneck, RO; Jones, CJ; Walesby, RK | 1 |
| Bussmann, WD; Kaltenbach, M; Kober, G; Schneider, W | 1 |
| Hawlicek, J; Kalenbach, M; Kirsten, N; Kober, G; Krause, A; Satter, P; Schneider, W; von Loh, D; Weyenmeyer, T | 1 |
| Gjørup, T; Godtfredsen, J; Kelbaek, H; Munck, O; Vestergaard, B | 1 |
| Metelitsa, VI | 1 |
| Hashimoto, H; Ito, T; Nakagawa, H; Ogawa, K; Okumura, K; Satake, T | 1 |
| Baldenkov, GN; Men'shikov, MIu; Mukharliamov, NM; Negresku, EV; Sazonova, LN | 1 |
| Moulds, RF | 1 |
| Roberts, R | 1 |
| Kolski, H; Moisson, P; Witchitz, S; Yvenou, L | 1 |
| Aronow, WS | 2 |
| Holzmann, S; Kukovetz, WR; Romanin, C | 1 |
| Conti, CR | 1 |
| Bennett, A; Melhuish, PB; Stamford, IF | 1 |
| Aberg, A; Engvall, J; Härkönen, R; Keyriläinen, O; Nyberg, G; Rautio, P; Rehnqvist, N; Rosenqvist, U; Ulvenstam, G; Uusitalo, A | 1 |
| Miller, CL | 1 |
| Kukovetz, WR; Romanin, C | 1 |
| Hader, S; Leitold, M | 1 |
| Ohba, Y; Sakai, K; Shiraki, Y | 1 |
| Flaherty, JT | 2 |
| Lee, WH; Medina, N; Packer, M; Yushak, M | 1 |
| Hisayama, T; Takayanagi, I; Toyoda, J | 2 |
| Johnen, R; Neuhaus, R; Solbach, C; Vydra, L | 1 |
| Martsevich, SIu; Metelitsa, VI; Riabokon', OS; Strel'tsov, AA | 1 |
| Atkins, JM | 1 |
| Booth, K; Gleadhill, DN; Moles, K; Morton, P; Nicholls, DP; Rowan, J | 1 |
| Lee, MG | 1 |
| Borbugulov, UM; Mazaev, AV; Men'shikov, MIu; Tkachuk, VA | 1 |
| Carlson, M; Thompson, RD | 1 |
| Henry, PJ; Horowitz, JD | 1 |
| Jähnchen, E | 1 |
| Kaltenbach, M; Schneider, W | 1 |
| Blagodatskikh, SV; Martsevich, SIu; Metelitsa, VI; Piotrovskiĭ, VK; Riabokon', OS | 1 |
| Elkayam, U; Freidenberger, L; Rahimtoola, SH; Roth, A; Weber, L | 1 |
| Ceschia, G; Pandullo, C; Pivotti, F; Pollavini, G; Scardi, S | 1 |
| Sal'nikov, SN; Vertkin, AL; Zharov, EI | 2 |
| Larin, NV; Pakulin, IA; Semin, SN; Sil'vestrov, VP; Surovov, IuA | 1 |
| Gathmann-Lewik, U; Heepe, W | 1 |
| De Martini, M; Foresti, A; Lotto, A; Massari, FM; Valentini, R | 1 |
| Giersch, KH; Kramar, M; Schneider, HT | 1 |
| Daskalov, TR | 1 |
| Berlin, R | 1 |
| Kampmann, JP | 1 |
| Jaeger, H; Lutz, D; Michaelis, K; Salama, ZB | 1 |
| Tenev, K; Todorov, R | 1 |
| Zeller, FP | 1 |
| Cohn, JN | 2 |
| Fung, HL | 4 |
| Hiramatsu, S; Katoh, Y; Kikawada, R; Kobayashi, A; Muramatsu, J | 1 |
| Cintron, GB; Conti, CR; Glasser, SP; Linares, E; Weston, BA | 1 |
| Thadani, U; Whitsett, TL | 1 |
| Cocco, C; Franceschini, L; Menegatti, G; Nidasio, GP; Rizzotti, P; Vassanelli, C | 1 |
| Schneeweiss, A | 1 |
| Imamura, T; Minoda, M; Seita, M; Taguchi, T; Tamura, K | 1 |
| Ambrosioni, E; Strocchi, E | 1 |
| Boudĭk, F; Bultas, J; Camek, R; Fabian, E; Karetová, D; Krupicka, P | 1 |
| Bennett, BM; Brien, JF; MacMillan, H; Marks, GS; Nakatsu, K; Tam, GS | 1 |
| Janicki, AG; Orzechowska-Juzwenko, K; Swiderska-Błońska, T | 1 |
| Chien, YW; Moore, L | 1 |
| Aldershvile, J; Svendsen, JH | 1 |
| Thadani, U; Whitsett, T | 1 |
| Ahmadinejad, M; Eghbal, B; Schneeweiss, A; Sorgenicht, W; Weiss, M | 1 |
| Barash, PG; Cahalan, M; Durkin, MA; Kaplan, J; Morris, RB; Thys, D | 1 |
| Blei, AT; Fung, HL; Ganger, D; Groszmann, R | 1 |
| Ahland, B; König, E; Schrör, K; Weiss, P | 1 |
| Bogaert, MG | 3 |
| Beyerle, A; Dirschinger, J; Hall, D; Reiniger, G; Rudolph, W | 1 |
| Kinoshita, M | 1 |
| Haight, V; Kydonieus, AF; Matz, S; Ng, S; Shah, KR; Zeoli, L | 1 |
| Aberg, A; Engvall, J; Keyriläinen, O; Nyberg, G; Olsson, G; Rehnqvist, N; Reinikainen, P; Rosenqvist, U; Ulvenstam, G; Uusitalo, A | 1 |
| Kaya, K; Mori, Y; Niimi, Y | 1 |
| Abe, M; Hayashi, T; Ida, T; Ito, Y; Matsuda, M; Obunai, Y; Sakakibara, T; Shimizu, Y; Takayama, Y; Tanaka, T | 1 |
| De Caterina, R; Dorso, CR; Tack-Goldman, K; Weksler, BB | 1 |
| Galer, IA; Hubner, PJ; Jones, PR | 1 |
| Martsevich, SIu; Metelitsa, VI; Shakarova, SSh; Strel'tsov, AA; Vygodin, VA | 1 |
| Ivanova, LK; Malinovskaia, IE; Shkliar, LV | 1 |
| Manyari, DE; Smith, ER; Spragg, J | 1 |
| Bouchier, IA; Hayes, PC; Jacyna, M; Morrison, L; Shepherd, AN | 1 |
| Angehrn, W; Gloor, HO; Steinbrunn, W | 1 |
| Steudel, H | 1 |
| Beck, OA | 1 |
| Luomanmäki, K | 1 |
| Bekhbudova, DA; Bochkareva, EV; Kokurina, EV; Ostrovskaia, TP; Urumbaev, RK | 1 |
| Mastalka, J; Smíd, J; Topinka, I | 1 |
| Bennett, BM; Brien, JF; Marks, GS; Nakatsu, K | 1 |
| Leier, CV | 1 |
| Conti, CR; Conti, JB; Feldman, RL; Hill, JA; Pepine, CJ | 1 |
| Packer, M | 1 |
| Kaplan, JA; Sivak, G; Thys, DM | 1 |
| Tremblay, G | 1 |
| Gleichmann, U; Kabelitz, K; Mannebach, H; Mertens, HM; Ohlmeier, H | 1 |
| Mazur, NA; Romakov, AIu; Sagirov, AM; Sumarokov, AB | 1 |
| Ageev, FT; Evdokimova, NKh; Mareev, VIu; Mukharliamov, NM; Novikov, SV | 1 |
| Grossmann, V; Hrdina, R | 1 |
| Barbakova, AA; Karbasnikova, GV; Valeeva, RM; Zabel'ian, OM; Zhuikova, AA | 1 |
| Keserü, P; Köszeginé Szalai, H; Paál, T; Török, I | 1 |
| Furkalo, NK; Ivashchenko, TI; Romanenko, AI | 1 |
| Offerhaus, L | 1 |
| Brodie, NH; O'Hara, H; O'Hara, J; Valle-Jones, JC | 1 |
| Kokurina, EV; Martsevich, SIu; Metelitsa, VI; Piotrovskiĭ, VK | 1 |
| Akhras, F; Jackson, G; Jefferies, S | 1 |
| Frazier, JE | 1 |
| Reynolds, JL | 1 |
| Bogaert, MG; Rosseel, MT | 1 |
| Fink, GB; Stipe, AA | 1 |
| Keyriläinen, O; Nyberg, G; Uusitalo, AJ | 1 |
| Hawkins, DM; Polakow, ES | 1 |
| Hastings, SG | 1 |
| Epstein, SE; Goldstein, RE | 2 |
| Hart, NJ; King, SB; Silverman, ME | 1 |
| Messini, M | 1 |
| Harrison, DC; Schroeder, JS; Silverman, JF | 1 |
| Cohn, K | 1 |
| Krieglstein, G; Leydhecker, W; Waller, W | 1 |
| Bussmann, WD; Kaltenbach, M; Löhner, J | 1 |
| Carroll, RJ; Falsetti, HL; Heinle, RA; Oliveros, RA; Ryan, GF | 1 |
| Brewer, J; Miller, MG | 1 |
| Böttcher, H | 1 |
| Gautieri, RF; Ward, CO | 1 |
| Blum, SW; Hefner, MA; Howe, BB; Quinn, JB; Winbury, MM | 1 |
| Fox, AC; Kaltman, AJ; King, MJ; Zir, LM | 1 |
| Gensini, GG; Huntington, PP | 1 |
| Wendt, RL | 1 |
| Cohn, KE; Selzer, A; Strauss, G; Sweatman, T | 1 |
| Johnson, EM; Lang, S; Needleman, P | 1 |
| Blehm, DJ; Harkey, AB; Johnson, EM; Needleman, P | 1 |
| Kaltenbach, M; Schellhorn, W; Tiedemann, I | 1 |
| Kaye, H; Mills, B; Winsor, T | 1 |
| Kleiger, RE; Martin, T | 1 |
| Bacos, J; Bashour, T; Cheng, TO; Kelser, GA; Weiss, L | 1 |
| Sewell, WH | 1 |
| Wendkos, MH | 2 |
| Gudbjarnason, S; Ogawa, K | 1 |
| Aronow, WS; Kaplan, MA | 1 |
| Aviado, DM; Bellet, S; Folle, LE | 1 |
| Aronow, WS; Chesluk, HM | 2 |
| Bermudez, GA; Butterfield, TK; Goldbarg, AN; Moran, JF; Nemickas, R | 1 |
| Bermudez, GA; Butterfield, TK; Goldbarg, AN; Morgan, JF; Nemickas, R | 1 |
| Dalvi, CP; Datey, KK | 1 |
| Both, A | 1 |
| Semler, HJ | 1 |
| Evans, JM; Gorman, PA | 1 |
| Beiser, GD; Epstein, SE; Goldstein, RE; Redwood, DR; Rosing, DR | 1 |
| Nager, F | 1 |
| Masters, AM | 1 |
| Leslie, RE | 2 |
| Da Costa, BC; Gensini, GG; Huntington, PP; Kelly, AE | 1 |
| Cheng, TO | 1 |
| Osnes, JB | 1 |
| Nossen, J | 1 |
| Bassenge, E; Busse, R | 1 |
| Brochier, M; Charbonnier, B; Itti, R; Lorgeron, JM; Pellois, A | 1 |
| MacAlpin, R | 1 |
| Akima, M; Hinohara, Y; Obatake, N; Sakai, K | 1 |
| Ruskoaho, H | 1 |
| Hirakawa, S; Ito, H | 1 |
| Kajiwara, N; Kanmatsuse, K; Onikura, S; Sato, K; Suzuki, Y; Toda, Y | 1 |
| Curfman, GD; Fung, HL; Heinsimer, JA; Lozner, EC | 1 |
| Bar-Meir, S; Bardan, E; Halpern, Z | 1 |
| Beythien, RD | 1 |
| Hochrein, H; Lehmann, HU; Traue, P; Witt, E | 1 |
| Davison, R; Kaplan, K; Lesch, M; Parker, M; Przybylek, J; Teagarden, JR | 1 |
| Goff, EU; Yu, WC | 1 |
| Featherstone, HJ; Stewart, DK | 1 |
| Blakeley, C; Tinker, J | 1 |
| Gelber, L; Papas, AN | 1 |
| Feely, J; Maclean, D | 1 |
| Brückner, JB; Hess, W; Patschke, D; Zimmermann, G | 1 |
| Dalal, JJ; Parker, JO; Yao, L | 1 |
| Bardet, J; Beaumont, D; Bourdarias, JP; Dubourg, O; Farcot, JC; Ferrier, A; Guéret, P; Léger, P; Rigaud, M | 1 |
| Häcker, W; Müller, G; Schneider, B | 1 |
| Fiedler, VB; Göbel, H; Nitz, RE | 1 |
| Horie, M; Hyon, H; Nagao, M; Nishida, S; Omote, S; Takizawa, A; Yasue, H | 1 |
| Ciafone, RA | 1 |
| Bloch, A; Imhoff, EW; Pavicic, L; Popadic, M; Rezakovic, D; Rutishauser, W | 1 |
| Bogaert, MG; Remon, JP | 1 |
| Fung, HL; Kamiya, A; Sutton, SC | 1 |
| Kayali, A | 1 |
| Kreuzer, H; Neuhaus, KL; Neumann, P; Sauer, G; Tebbe, U | 1 |
| Draxler, V; Hammerle, A; Schindler, I; Zadrobilek, E | 1 |
| Blasini, R; Brügmann, U; Reiniger, G; Rudolph, W | 2 |
| Kreye, VA; Stiefel, A | 2 |
| Curfman, GD | 1 |
| Bashir, A; Culling, W; Dalal, JJ; Griffiths, BE; Sheridan, DJ; Singh, H | 1 |
| Kodama, K; Koretsune, Y; Nanto, S; Taniura, K | 1 |
| Arsura, E; Greengart, A; Guadagnino, V; Hollander, G; Lichstein, E; Nicchi, V; Sanders, M | 1 |
| Inden, M; Itou, M; Kawahira, S; Morimoto, Y; Nakano, T; Noda, E; Takasaki, H; Takezawa, H; Tanimura, H | 1 |
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| Funae, Y; Hai, S; Hirohashi, K; Minamiyama, Y; Okada, S; Takemura, S; Yamasaki, K | 1 |
| Borovkova, NV; Chernov, VI; Demochko, AV; Idrisova, EM; Karpov, RS; Kladieva, EA; Shishkina, AA; Vorob'eva, EV | 1 |
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| Appenzeller, O; Claydon, VE; Gebremedhin, A; Gulli, G; Hainsworth, R; Qualls, C; Slessarev, M; Zenebe, G | 1 |
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| Adams, MA; Bennett, BM; Frederiksen, LJ; Graham, CH; Macdonald-Goodfellow, SK; Maxwell, LR; Siemens, DR; Sullivan, R | 1 |
| Chen, JZ; Guo, JX; He, Q; Jia, SQ; Li, TD; Li, ZQ; Shan, YD; Wei, JP; Wu, ZG; Yang, XC; You, K; Zhu, WL | 1 |
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113 review(s) available for isosorbide dinitrate and nitroglycerin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Molsidomin compared to nitrates. Use in patients with manifest coronary disease].
Topics: Adrenergic beta-Antagonists; Aged; Calcium; Coronary Disease; Drug Evaluation; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Morpholines; Nitrates; Nitroglycerin; Oxadiazoles; Sydnones | 1979 |
[Cardiac therapy in the old patient].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Body Water; Calcium; Clonidine; Digitalis Glycosides; Diuretics; Dose-Response Relationship, Drug; Drug Tolerance; Glomerular Filtration Rate; Heart Diseases; Heart Failure; Humans; Hypertension; Isosorbide Dinitrate; Kidney; Methyldopa; Middle Aged; Nitroglycerin; Prazosin; Reserpine; Water-Electrolyte Balance | 1979 |
[Vasodilator therapy in heart failure (author's transl)].
Topics: Aortic Valve Insufficiency; Coronary Vessels; Heart Failure; Heart Septal Defects, Ventricular; Humans; Isosorbide Dinitrate; Mitral Valve Insufficiency; Mitral Valve Stenosis; Myocardial Infarction; Nitroglycerin; Nitroprusside; Vasodilator Agents | 1978 |
Duration of action of isosorbide dinitrate.
Topics: Angina Pectoris; Clinical Trials as Topic; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Nitroglycerin; Placebos; Time Factors | 1979 |
Drug therapy for cardiovascular disease in the aged.
Topics: Adrenergic beta-Antagonists; Aged; Anti-Bacterial Agents; Arrhythmias, Cardiac; Benzothiadiazines; Cardiac Rehabilitation; Cardiac Surgical Procedures; Cardiovascular Diseases; Coronary Disease; Delayed-Action Preparations; Digoxin; Diuretics; Endocarditis; Female; Heart Failure; Humans; Hypertension; Hypertension, Malignant; Hyperthyroidism; Hypothyroidism; Isosorbide Dinitrate; Male; Methyldopa; Middle Aged; Nitroglycerin; Sodium Chloride Symporter Inhibitors | 1975 |
[Vasodilator therapy of congestive heart failure].
Topics: Acute Disease; Blood Pressure; Cardiac Output; Chronic Disease; Heart Failure; Humans; Isosorbide Dinitrate; Myocardium; Nitroglycerin; Nitroprusside; Oxygen Consumption; Phentolamine; Vascular Resistance; Vasodilator Agents | 1977 |
Nitroglycerin ointment: a review.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Delayed-Action Preparations; Heart Ventricles; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Ointments; Physical Exertion | 1977 |
[Vasodilator agents in the treatment of heart failure].
Topics: Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Minoxidil; Nitroglycerin; Nitroprusside; Phentolamine; Prazosin; Vasodilator Agents | 1978 |
[Treatment of cardiac failure with vasodilators (author's transl)].
Topics: Cardiac Glycosides; Diuretics; Drug Therapy, Combination; Heart Failure; Hydralazine; Hypotension; Isosorbide Dinitrate; Nitroglycerin; Nitroprusside; Phenoxybenzamine; Phentolamine; Prazosin; Vasodilator Agents | 1978 |
Comparative effects of nitroglycerin and isosorbide dinitrate on coronary collateral vessels and ischemic myocardium in dogs.
Topics: Animals; Collateral Circulation; Coronary Disease; Coronary Vessels; Dogs; Isosorbide Dinitrate; Nitroglycerin; Time Factors | 1976 |
Organic nitrate metabolism.
Topics: Animals; Biodegradation, Environmental; Dogs; Guinea Pigs; Humans; In Vitro Techniques; Isosorbide Dinitrate; Mice; Nitrates; Nitroglycerin; Oxidoreductases; Pentaerythritol Tetranitrate; Propylene Glycols; Rats; Time Factors | 1976 |
[Drug therapy of acute myocardial infarction without cardiogenic shock and thrombolytic therapy excluded].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Calcium Channel Blockers; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Nitroprusside; Platelet Aggregation Inhibitors; Treatment Outcome | 1992 |
[Nitrate derivatives and hemostasis: fundamental concepts and clinical implications].
Topics: Bleeding Time; Hemostasis; Humans; Isosorbide Dinitrate; Nitric Oxide; Nitroglycerin; Platelet Activation | 1992 |
[Differential action of nitrate derivatives and arterial vasodilators on coronary circulation. An experimental approach and therapeutic consequences].
Topics: Animals; Benzopyrans; Coronary Circulation; Coronary Disease; Cromakalim; Diltiazem; Dogs; Drug Therapy, Combination; Female; Isosorbide Dinitrate; Male; Nitroglycerin; Pyrroles; Vasodilator Agents | 1992 |
[Nitrate derivatives and coronary vasomotricity].
Topics: Coronary Artery Disease; Coronary Vasospasm; Coronary Vessels; Humans; Isosorbide Dinitrate; Nitroglycerin; Vasomotor System | 1992 |
[Tolerance in treatment with nitrates].
Topics: Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Risk Factors | 1992 |
[Evaluation of tolerance during intravenous administration of low dose of isosorbide dinitrate in the treatment of unstable angina].
Topics: Acetylcysteine; Adult; Aged; Angina, Unstable; Blood Pressure; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Tachyphylaxis | 1992 |
A practical guide to nitrate use.
Topics: Angina Pectoris; Heart Failure; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Pulmonary Edema | 1991 |
Clinical experience with Imdur in angina pectoris. A review.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Delayed-Action Preparations; Drug Interactions; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitroglycerin | 1990 |
Relationship between the inhibition of receptor-induced increase in cytosolic free calcium concentration and the vasodilator effects of nitrates in patients with congestive heart failure.
Topics: Adult; Blood Platelets; Calcium; Heart Failure; Humans; Isosorbide Dinitrate; Middle Aged; Nifedipine; Nitrates; Nitroglycerin; Nitroprusside; Plethysmography | 1990 |
Nitrate therapy in the elderly.
Topics: Aged; Aging; Bradycardia; Coronary Disease; Half-Life; Humans; Hypotension; Isosorbide Dinitrate; Nitroglycerin | 1990 |
Development of long-acting nitrate delivery systems.
Topics: Administration, Cutaneous; Administration, Oral; Angina Pectoris; Delayed-Action Preparations; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1990 |
Nitrate tolerance. A problem during continuous nitrate administration.
Topics: Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Exercise; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1990 |
Nitrates: why and how should they be used today? Current status of the clinical usefulness of nitroglycerin, isosorbide dinitrate and isosorbide-5-mononitrate.
Topics: Angina Pectoris; Coronary Disease; Delayed-Action Preparations; Drug Administration Schedule; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1990 |
Nitrovasodilators and portal hypertension.
Topics: Humans; Hypertension, Portal; Isosorbide Dinitrate; Nitroglycerin; Vasodilator Agents | 1990 |
[Nitrates in the treatment of heart failure].
Topics: Dose-Response Relationship, Drug; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1990 |
Mechanisms of nitrate tolerance--influence of the metabolic activation pathways.
Topics: Animals; Biotransformation; Coronary Disease; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1990 |
[Diagnosis and therapy of functional disorders of the bile ducts].
Topics: Biliary Dyskinesia; Endoscopy; Humans; Isosorbide Dinitrate; Nitroglycerin; Sphincter of Oddi | 1989 |
[Transdermal forms of nitrates].
Topics: Administration, Cutaneous; Angina Pectoris; Delayed-Action Preparations; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1989 |
Stable angina as a manifestation of ischemic heart disease: medical management.
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Calcium Channel Blockers; Cardiac Catheterization; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Exercise Test; Female; Humans; Hypertension; Isosorbide Dinitrate; Life Style; Male; Middle Aged; Nitroglycerin; Physical Exertion; Prognosis; Risk; Time Factors | 1985 |
Pharmacologic treatment of angina: nitrate tolerance.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Drug Administration Schedule; Drug Therapy, Combination; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitroglycerin; Vasodilator Agents | 1988 |
Relationship between pharmacokinetics and pharmacodynamics of organic nitrates.
Topics: Angina Pectoris; Dose-Response Relationship, Drug; Drug Tolerance; Hemodynamics; Humans; Isosorbide Dinitrate; Kinetics; Nitrates; Nitroglycerin | 1986 |
Pharmacokinetics of various preparations of organic nitrates.
Topics: Delayed-Action Preparations; Humans; Isosorbide Dinitrate; Kinetics; Nitrates; Nitroglycerin | 1987 |
Tolerance to organic nitrates in ischemic heart disease.
Topics: Coronary Disease; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1987 |
Glyceryl trinitrate (nitroglycerin) and the organic nitrates. Choosing the method of administration.
Topics: Angina Pectoris; Heart Failure; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitrates; Nitroglycerin | 1987 |
Pharmacokinetics and pharmacodynamics of organic nitrates.
Topics: Animals; Cardiac Output; Half-Life; Humans; Isosorbide Dinitrate; Metabolic Clearance Rate; Nitroglycerin | 1987 |
Nitrate therapy: continuous or pulse dosing.
Topics: Angina Pectoris; Delayed-Action Preparations; Drug Tolerance; Heart Failure; Humans; Isosorbide Dinitrate; Nitroglycerin | 1987 |
[Slow-release nitrates: a critical review].
Topics: Coronary Disease; Delayed-Action Preparations; Humans; Isosorbide Dinitrate; Nitroglycerin | 1987 |
Transdermal drug delivery: a review of pharmaceutics, pharmacokinetics, and pharmacodynamics.
Topics: Administration, Cutaneous; Animals; Aspirin; Clonidine; Gonadal Steroid Hormones; Humans; Isosorbide Dinitrate; Nitroglycerin; Prostaglandins, Synthetic; Scopolamine; Skin; Skin Physiological Phenomena | 1988 |
Relationship of pharmacokinetic and pharmacodynamic properties of the organic nitrates.
Topics: Angina Pectoris; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Nitroglycerin | 1988 |
Organic nitrates in portal hypertension.
Topics: Animals; Humans; Hypertension, Portal; Isosorbide Dinitrate; Nitroglycerin; Splanchnic Circulation | 1988 |
Pharmacokinetics of organic nitrates in man: an overview.
Topics: Absorption; Administration, Cutaneous; Administration, Sublingual; Humans; Injections, Intravenous; Isosorbide Dinitrate; Nitroglycerin | 1988 |
Hercon technology for transdermal delivery of drugs.
Topics: Administration, Cutaneous; Animals; Biological Availability; Clonidine; Delayed-Action Preparations; Equipment Design; Estradiol; Humans; Isosorbide Dinitrate; Nitroglycerin; Prostaglandins; Scopolamine; Technology, Pharmaceutical | 1986 |
Efficacy of different forms of nitrates in angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Calcium; Drug Tolerance; Humans; Isosorbide Dinitrate; Kinetics; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Nucleotides, Cyclic; Ointments; Vasodilation | 1985 |
Hemodynamic effects of nitroglycerin and long-acting nitrates.
Topics: Angina Pectoris; Arteries; Arterioles; Blood Circulation; Coronary Circulation; Coronary Disease; Extremities; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Lung; Nitroglycerin; Regional Blood Flow; Splanchnic Circulation; Sympathetic Nervous System; Time Factors; Veins | 1985 |
Nitrate tolerance.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Emulsions; Heart Failure; Humans; Isosorbide Dinitrate; Nitroglycerin; Ointments; Time Factors | 1985 |
Isosorbide dinitrate and nifedipine in variant angina pectoris.
Topics: Angina Pectoris, Variant; Clinical Trials as Topic; Coronary Vasospasm; Coronary Vessels; Double-Blind Method; Drug Therapy, Combination; Humans; Isosorbide Dinitrate; Nifedipine; Nitroglycerin; Prospective Studies; Vasodilation | 1985 |
Mechanisms of nitrate action in patients with severe left ventricular failure: conceptual problems with the theory of venosequestration.
Topics: Arteries; Blood Volume; Heart Failure; Heart Ventricles; Humans; Isosorbide Dinitrate; Nitroglycerin; Pulmonary Circulation; Stroke Volume; Vascular Resistance; Vasodilation; Venous Pressure | 1985 |
The role of isosorbide dinitrate in the treatment of perioperative hypertension.
Topics: Clinical Trials as Topic; Coronary Artery Bypass; Double-Blind Method; Humans; Hypertension; Infusions, Parenteral; Isosorbide Dinitrate; Nitroglycerin; Nitroprusside; Preoperative Care | 1985 |
Pharmacology of nitroglycerin and long-acting nitrates.
Topics: Absorption; Administration, Oral; Administration, Topical; Angina Pectoris; Animals; Cheek; Delayed-Action Preparations; Drug Tolerance; Heart Failure; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Kinetics; Mouth Floor; Mouth Mucosa; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Vasodilator Agents | 1985 |
Nitrate formulations and drug delivery systems--an overview.
Topics: Animals; Biological Availability; Drug Tolerance; Isosorbide Dinitrate; Kinetics; Nitrates; Nitroglycerin; Rats | 1985 |
Editorial: Nitrates in the prophylactic treatment of angina pectoris.
Topics: Angina Pectoris; Exercise Test; Heart; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1973 |
Angina pectoris: pathophysiology, evaluation, and treatment.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Cardiac Catheterization; Carotid Sinus; Coronary Disease; Coronary Vessels; Eating; Electric Stimulation; Electrocardiography; Environmental Exposure; Exercise Test; Fibrinolysis; Heart; Heart Rate; Humans; Isosorbide Dinitrate; Myocardium; Nitroglycerin; Oxygen Consumption; Physical Education and Training; Physical Exertion; Propranolol; Temperature | 1971 |
Organic nitrates in angina pectoris.
Topics: Administration, Oral; Amyl Nitrite; Angina Pectoris; Blood Pressure; Coronary Circulation; Drug Tolerance; Heart Rate; Humans; Isosorbide Dinitrate; Mouth Floor; Muscle Contraction; Nitrates; Nitroglycerin; Oxygen Consumption; Physical Exertion; Vasodilator Agents | 1972 |
Some pharmacological properties of organic nitrates.
Topics: Angina Pectoris; Animals; Arterioles; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Drug Tolerance; Humans; Inactivation, Metabolic; Isosorbide Dinitrate; Liver; Muscle, Smooth, Vascular; Myocardium; Nitrates; Nitroglycerin; Oxyhemoglobins; Vasodilation; Venous Pressure | 1984 |
[Effect of nitrates, nitrate-like substances, calcium antagonists and beta-adrenergic receptor blockers on peripheral circulation].
Topics: Adrenergic beta-Antagonists; Amyl Nitrite; Angina Pectoris; Animals; Blood Circulation; Calcium Channel Blockers; Humans; Isosorbide Dinitrate; Molsidomine; Muscle Contraction; Muscles; Nitrates; Nitroglycerin; Nitroprusside; Rats; Sydnones | 1982 |
[The place of isotopic exploration in the evaluation of anti-anginal drugs].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Disease; Dipyridamole; Dogs; Heart; Hemodynamics; Humans; Isosorbide Dinitrate; Nitroglycerin; Radioisotopes; Technetium; Thallium; Tomography, Emission-Computed; Xenon Radioisotopes | 1983 |
Treatment of vasospastic angina.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anemia; Angina Pectoris, Variant; Atropine; Diltiazem; Drug Therapy, Combination; Epoprostenol; Exercise Therapy; Female; Humans; Hypertension; Hyperthyroidism; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Nitroglycerin; Nitroprusside; Nylidrin; Verapamil | 1983 |
[Coronary arteries].
Topics: Aged; Angina Pectoris; Angioplasty, Balloon; Catheterization; Coronary Angiography; Humans; Infusions, Intra-Arterial; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Urokinase-Type Plasminogen Activator | 1984 |
Vasodilators in acute circulatory failure.
Topics: Albuterol; Captopril; Chlorpromazine; Heart Failure; Humans; Isosorbide Dinitrate; Nitroglycerin; Nitroprusside; Phentolamine; Vasodilator Agents | 1983 |
[Acute and long-term nitrate treatment of angina pectoris].
Topics: Acute Disease; Administration, Oral; Angina Pectoris; Bandages; Drug Tolerance; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Long-Term Care; Mouth Floor; Nitroglycerin; Ointments | 1983 |
Nitrate tolerance and dependence.
Topics: Ambulatory Care; Angina Pectoris; Animals; Cardiovascular Diseases; Dogs; Drug Tolerance; Heart Failure; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Occupational Medicine; Propranolol; Rabbits; Rats; Substance-Related Disorders; Time Factors | 1980 |
[Drug treatment of chronic coronary disease].
Topics: Chronic Disease; Coronary Circulation; Coronary Disease; Humans; Isosorbide Dinitrate; Myocardium; Nitroglycerin; Oxygen Consumption; Pentaerythritol Tetranitrate; Propranolol; Vasodilator Agents | 1980 |
Vasodilator therapy of congestive heart failure.
Topics: Aortic Valve Insufficiency; Captopril; Dobutamine; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Minoxidil; Mitral Valve Insufficiency; Nitroglycerin; Nitroprusside; Phentolamine; Physical Exertion; Piperazines; Prazosin; Quinazolines; Time Factors; Vasodilator Agents | 1980 |
Glyceryl trinitrate (nitroglycerin) ointment and isosorbide dinitrate: a review of their pharmacological properties and therapeutic use.
Topics: Angina Pectoris; Drug Interactions; Drug Tolerance; Hemodynamics; Humans; Isosorbide Dinitrate; Nitroglycerin; Ointments; Regional Blood Flow; Substance-Related Disorders | 1982 |
[Treatment of coronary arterial spasm].
Topics: Amiodarone; Coronary Vasospasm; Denervation; Diltiazem; Humans; Isosorbide Dinitrate; Myocardial Revascularization; Nifedipine; Nitroglycerin; Phenoxybenzamine; Phentolamine; Reserpine; Verapamil | 1982 |
[Drug therapy in angina pectoris].
Topics: Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Cardiovascular Agents; Coronary Vasospasm; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Platelet Aggregation Inhibitors; Vasodilator Agents | 1995 |
Chronic stable angina pectoris. Strategies for effective drug therapy.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Humans; Isosorbide Dinitrate; Nitroglycerin | 1995 |
Pharmacologic therapy of angina pectoris.
Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Aspirin; Calcium Channel Blockers; Drug Therapy, Combination; Enoximone; Heparin; Humans; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Piperazines; Ranolazine; Vasodilator Agents | 1995 |
The role of nitrates in coronary heart disease.
Topics: Angina Pectoris; Coronary Disease; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Vasodilation | 1995 |
Short and long-acting oral nitrates for stable angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Delayed-Action Preparations; Drug Therapy, Combination; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; United States; United States Food and Drug Administration; Vasodilator Agents | 1994 |
Ointments and transdermal nitroglycerin patches for stable angina pectoris.
Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Angina Pectoris; Delayed-Action Preparations; Drug Delivery Systems; Drug Tolerance; Exercise; Humans; Isosorbide Dinitrate; Nitroglycerin; Ointments; Product Surveillance, Postmarketing | 1994 |
Clinical pharmacokinetics of nitrates.
Topics: Angina Pectoris; Delayed-Action Preparations; Drug Administration Routes; Half-Life; Humans; Isosorbide Dinitrate; Liver; Nitrates; Nitroglycerin; Structure-Activity Relationship; Vasodilation; Vasodilator Agents | 1994 |
Mechanisms of action of nitrates.
Topics: Angina Pectoris; Blood Platelets; Cyclic GMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Esterases; Glutathione Transferase; Heart; Heart Failure; Humans; Isosorbide Dinitrate; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Infarction; Nitrates; Nitroglycerin; Oxygen Consumption; Structure-Activity Relationship; Vasodilator Agents | 1994 |
Mechanisms of nitrate tolerance.
Topics: Angina Pectoris; Animals; Drug Administration Routes; Drug Therapy, Combination; Drug Tolerance; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Sulfhydryl Compounds; Vascular Resistance | 1994 |
Esophageal chest pain: state of the art.
Topics: Bethanechol; Bethanechol Compounds; Calcium Channel Blockers; Chest Pain; Diagnosis, Differential; Edrophonium; Ergonovine; Esophageal Achalasia; Esophageal Diseases; Gastroesophageal Reflux; Heart Diseases; Humans; Isosorbide Dinitrate; Mental Disorders; Nitroglycerin; Pentagastrin; Vasopressins | 1993 |
[Vasodilator therapy in cardiac failure].
Topics: Adrenergic beta-Antagonists; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Nitroglycerin; Norepinephrine; Renin-Angiotensin System; Sympathetic Nervous System; Vasodilator Agents | 1993 |
Nitrate therapy and the development of tolerance.
Topics: Angina Pectoris; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilator Agents | 1993 |
Microbial cleavage of nitrate esters: defusing the environment.
Topics: Biodegradation, Environmental; Collodion; Environmental Microbiology; Environmental Pollutants; Ethylene Glycols; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate | 1993 |
Organic nitrates in portal hypertension.
Topics: Animals; Collateral Circulation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Circulation; Liver Cirrhosis; Nitrates; Nitroglycerin; Vasodilator Agents | 1994 |
Haemodynamic and clinical effects of an intravenous potassium channel opener--a review.
Topics: Administration, Sublingual; Angina, Unstable; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Vasodilator Agents | 1993 |
Organic nitrates: new formulations and their clinical advantages.
Topics: Cardiovascular Diseases; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Randomized Controlled Trials as Topic | 1996 |
Nitrate therapy for stable angina pectoris.
Topics: Angina Pectoris; Drug Therapy, Combination; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Vasodilator Agents | 1998 |
Cervical ripening after nitric oxide.
Topics: Animals; Cervix Uteri; Female; Humans; Isosorbide Dinitrate; Labor Stage, First; Nitric Oxide; Nitroglycerin; Nitroprusside; Pregnancy; Uterine Contraction | 1998 |
Clinical pharmacokinetics of vasodilators. Part II.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Alprostadil; Amrinone; Carbazoles; Carvedilol; Enoximone; Female; Humans; Iloprost; Imidazoles; Indoramin; Isosorbide Dinitrate; Labetalol; Milrinone; Molsidomine; Nitroglycerin; Nitroprusside; Oxyfedrine; Pentaerythritol Tetranitrate; Phosphodiesterase Inhibitors; Piperazines; Prazosin; Pregnancy; Propanolamines; Pyridones; Theophylline; Trapidil; Vasodilator Agents | 1998 |
The 'vasovagal effect' of nitrates: an under-recognised complication of nitrate use.
Topics: Adult; Bradycardia; Humans; Hypotension; Isosorbide Dinitrate; Male; Myocardial Ischemia; Nitroglycerin; Vasodilator Agents | 1998 |
[The treatment of chronic fissure in ano with nitrate ointment].
Topics: Administration, Topical; Female; Fissure in Ano; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Ointments; Treatment Outcome; Vasodilator Agents | 1999 |
The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Endoscopy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Isosorbide Dinitrate; Ligation; Liver Transplantation; Lypressin; Middle Aged; Mineralocorticoid Receptor Antagonists; Nadolol; Nitric Oxide Donors; Nitroglycerin; Portasystemic Shunt, Transjugular Intrahepatic; Propranolol; Randomized Controlled Trials as Topic; Recurrence; Sclerotherapy; Spironolactone; Terlipressin; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
[Nitrates in cardiology practice].
Topics: Humans; Isosorbide Dinitrate; Molsidomine; Myocardial Ischemia; Nitroglycerin; Vasodilator Agents | 2000 |
[Drug treatment of erection disorders in patients with cardiovascular disease].
Topics: Cardiovascular Diseases; Contraindications; Drug Interactions; Erectile Dysfunction; Humans; Isosorbide Dinitrate; Male; Netherlands; Nitric Oxide Donors; Nitroglycerin; Phosphodiesterase Inhibitors; Piperazines; Practice Guidelines as Topic; Purines; Sildenafil Citrate; Sulfones | 2001 |
[Angina attack caused by 5-fluorouracil infusion--report of a case and review of the literature].
Topics: Angina Pectoris; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Isosorbide Dinitrate; Liver Neoplasms; Middle Aged; Nitroglycerin; Sigmoid Neoplasms | 2002 |
[Antianginal drugs].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Agents; Humans; Isosorbide Dinitrate; Nitroglycerin; Vasodilator Agents | 1994 |
[Antianginal drugs].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Contraindications; Humans; Isosorbide Dinitrate; Nitroglycerin | 2003 |
Nitrate stimulated tilt table testing: a review of the literature.
Topics: Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Reproducibility of Results; Syncope, Vasovagal; Tilt-Table Test; Vasodilator Agents | 2003 |
Cardiovascular effects of the 3 phosphodiesterase-5 inhibitors approved for the treatment of erectile dysfunction.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenergic alpha-Antagonists; Arteriosclerosis; Blood Pressure; Carbolines; Contraindications; Coronary Disease; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Interactions; Endothelium, Vascular; Erectile Dysfunction; Heart Rate; Humans; Hypotension; Imidazoles; Isosorbide Dinitrate; Male; Molecular Structure; Myocardial Infarction; Nitric Oxide Donors; Nitroglycerin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Randomized Controlled Trials as Topic; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilation; Vasodilator Agents | 2004 |
[Anti-angina treatment in stable forms of angina pectoris with emphasis on nitrates].
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Nitroglycerin; Vasodilator Agents | 1999 |
Chemical sphincterotomy--first line of treatment for chronic anal fissure.
Topics: Botulinum Toxins; Calcium Channel Blockers; Chronic Disease; Diltiazem; Fissure in Ano; Humans; Isosorbide Dinitrate; Nifedipine; Nitroglycerin; Vasodilator Agents | 2005 |
[Nitrates. The place in contemporary therapy of ischemic heart disease].
Topics: Angina Pectoris; Contraindications; Delayed-Action Preparations; Humans; Isosorbide Dinitrate; Myocardial Infarction; Myocardial Ischemia; Nitrates; Nitroglycerin; Time Factors; Vasodilator Agents | 2005 |
Side effects of using nitrates to treat angina.
Topics: Angina Pectoris; Coronary Disease; Drug Interactions; Headache; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Phosphodiesterase Inhibitors; Randomized Controlled Trials as Topic; Syncope; Vasodilator Agents | 2006 |
Chinese herbal medicine suxiao jiuxin wan for angina pectoris.
Topics: Angina Pectoris; Drugs, Chinese Herbal; Humans; Isosorbide Dinitrate; Nitroglycerin; Phytotherapy; Randomized Controlled Trials as Topic; Vasodilator Agents | 2008 |
[Endothelium and nitric oxide].
Topics: Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis; Endothelium, Vascular; Homeostasis; Humans; Hypolipidemic Agents; Isosorbide Dinitrate; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Vasodilator Agents | 2008 |
Anal fissure: a review.
Topics: Anal Canal; Botulinum Toxins; Calcium Channel Blockers; Dilatation; Fissure in Ano; Humans; Isosorbide Dinitrate; Nitroglycerin; Surgical Flaps | 2008 |
[Recent findings on nitrates: their action, bioactivation and development of tolerance].
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Coronary Disease; Drug Tolerance; Endothelium, Vascular; Guanylate Cyclase; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Oxidative Stress; Pentaerythritol Tetranitrate; Reactive Oxygen Species; Vasodilation; Vasodilator Agents | 2008 |
Non-hemodynamic effects of organic nitrates and the distinctive characteristics of pentaerithrityl tetranitrate.
Topics: Animals; Drug Administration Schedule; Drug Tolerance; Heart Diseases; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Oxidative Stress; Pentaerythritol Tetranitrate; Reactive Oxygen Species; Vasodilator Agents | 2009 |
Nitrates for acute heart failure syndromes.
Topics: Acute Disease; Adult; Heart Failure; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Randomized Controlled Trials as Topic; Syndrome; Vasodilator Agents | 2013 |
Anal fissure and stenosis.
Topics: Anal Canal; Anus Diseases; Botulinum Toxins, Type A; Calcium Channel Blockers; Constriction, Pathologic; Dietary Fiber; Dilatation; Fissure in Ano; Humans; Isosorbide Dinitrate; Neuromuscular Agents; Nitric Oxide Donors; Nitroglycerin; Surgical Flaps; Treatment Outcome | 2013 |
The nitric oxide pathway and possible therapeutic options in pre-eclampsia.
Topics: Aldehyde Oxidoreductases; Clinical Trials as Topic; Endothelium, Vascular; Female; Humans; Isosorbide Dinitrate; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Phosphodiesterase Inhibitors; Piperazines; Pre-Eclampsia; Pregnancy; Purines; S-Nitrosothiols; Sildenafil Citrate; Sulfonamides | 2014 |
Pharmacologic management of chronic stable angina.
Topics: Adrenergic beta-Antagonists; Angina, Stable; Benzazepines; Calcium Channel Blockers; Cardiovascular Agents; Humans; Isosorbide Dinitrate; Ivabradine; Nicorandil; Nitroglycerin; Ranolazine; Sodium Channel Blockers; Vasodilator Agents | 2015 |
Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non-cardiac surgery.
Topics: Cause of Death; Heart Diseases; Humans; Isosorbide Dinitrate; Morbidity; Nicorandil; Nitroglycerin; Postoperative Complications; Randomized Controlled Trials as Topic; Surgical Procedures, Operative; Vasodilator Agents | 2016 |
Sini decoction as an adjuvant therapy for angina pectoris: a systematic review of randomized controlled trials.
Topics: Angina Pectoris; China; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Isosorbide Dinitrate; Nitroglycerin; Randomized Controlled Trials as Topic | 2017 |
Cardiac Memory: A Case Report and Review of the Literature.
Topics: Aged; Amlodipine; Arrhythmias, Cardiac; Aspirin; Bundle-Branch Block; Chest Pain; Electrocardiography; Emergency Service, Hospital; Enalapril; Headache; Heart Ventricles; Humans; Isosorbide Dinitrate; Male; Nausea; Nitroglycerin; Platelet Aggregation Inhibitors; Vasodilator Agents; Vomiting | 2019 |
The Efficacy of Nitrates for Bone Health: A Systematic Review and Meta-Analysis of Observational and Randomized Controlled Studies.
Topics: Bone and Bones; Bone Density; Female; Fractures, Bone; Humans; Isosorbide Dinitrate; Male; Nitrates; Nitric Oxide Donors; Nitroglycerin; Risk Factors | 2022 |
151 trial(s) available for isosorbide dinitrate and nitroglycerin
| Article | Year |
|---|---|
[Drug therapy of coronary heart disease (author's transl)].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium; Clinical Trials as Topic; Coronary Disease; Drug Therapy, Combination; Exercise Test; Humans; Isosorbide Dinitrate; Nifedipine; Nitroglycerin; Verapamil | 1977 |
[Evaluation of the therapeutic efficacy of 4 different delayed-action nitro-derivatives on S-T changes after exercise tests].
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Circulation; Delayed-Action Preparations; Drug Evaluation; Electrocardiography; Exercise Test; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Placebos | 1978 |
Comparison of placebo, nitroglycerin, and isosorbide dinitrate for effectiveness of relief of angina and duration of action.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Placebos | 1979 |
Duration of action of isosorbide dinitrate.
Topics: Angina Pectoris; Clinical Trials as Topic; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Nitroglycerin; Placebos; Time Factors | 1979 |
[Treatment of angina pectoris with stenoptin. Placebo controlled double-blind study].
Topics: Angina Pectoris; Drug Combinations; Isosorbide Dinitrate; Nitroglycerin; Placebos; Verapamil | 1979 |
Sustained hemodynamic and antianginal effect of high dose oral isosorbide dinitrate.
Topics: Administration, Oral; Adult; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Electrocardiography; Exercise Test; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1977 |
Is the use of long acting nitrates beneficial in the patient with angina pectoris? (The positive side).
Topics: Administration, Oral; Angina Pectoris; Biological Availability; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Drug Stability; Electrocardiography; Heart Failure; Heart Rate; Humans; Isosorbide Dinitrate; Kinetocardiography; Myocardial Contraction; Nitrates; Nitroglycerin; Ointments; Oxygen Consumption; Vascular Resistance | 1977 |
Is the use of long acting nitrates beneficial in the patient with angina pectoris? (The negative side).
Topics: Angina Pectoris; Animals; Clinical Trials as Topic; Coronary Circulation; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Inactivation, Metabolic; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1977 |
Acute drug testing with nitrates: angina relief during treadmill exercise.
Topics: Adult; Angina Pectoris; Drug Evaluation; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Physical Exertion | 1977 |
Hemodynamics and antianginal effects of high dose oral isosorbide dinitrate after chronic use.
Topics: Adult; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Exercise Test; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Placebos | 1977 |
Comparative hemodynamic effects of chewable isosorbide dinitrate and nitroglycerin in patients with congestive heart failure.
Topics: Administration, Oral; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Delayed-Action Preparations; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Mouth Floor; Nitroglycerin; Placebos | 1975 |
Hemodynamic effects of isosorbide dinitrate vs nitroglycerin in patients with unstable angina.
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Echocardiography; Female; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Mouth Floor; Nitroglycerin; Placebos; Rest | 1976 |
[Hemodynamic and electrocardiographic prolonged nitrate effect during frequency load in coronary disease].
Topics: Blood Pressure; Cardiac Output; Coronary Disease; Electrocardiography; Humans; Isosorbide Dinitrate; Nitroglycerin; Physical Exertion; Pulmonary Artery; Time Factors | 1976 |
Selected issues from an overview on nicorandil: tolerance, duration of action, and long-term efficacy.
Topics: Administration, Oral; Administration, Sublingual; Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Exercise; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Niacinamide; Nicorandil; Nitroglycerin | 1992 |
A comparison of angioplasty with medical therapy in the treatment of single-vessel coronary artery disease. Veterans Affairs ACME Investigators.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Exercise Test; Follow-Up Studies; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Random Allocation; Recurrence | 1992 |
Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle.
Topics: Amlodipine; Angina Pectoris; Diastole; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Metipranolol; Metoprolol; Myocardial Infarction; Nitroglycerin; Systole; Ventricular Function, Left | 1992 |
A comparison of the day-long antianginal effectiveness of nitroglycerin patches with that of three-times-daily isosorbide dinitrate: a double-blind study using dose titration.
Topics: Administration, Cutaneous; Aged; Angina Pectoris; Atenolol; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise Test; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Propranolol | 1992 |
[Effects of peripheral vasodilators on arrhythmia in patients with chronic coronary insufficiency].
Topics: Arrhythmias, Cardiac; Captopril; Female; Heart Failure; Heart Ventricles; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Nitroglycerin; Vasodilator Agents | 1992 |
Hemodynamics and exercise tolerance during application of transdermal systems with phasic nitroglycerin (NTG) release in comparison to 20 mg isosorbide mononitrate.
Topics: Administration, Cutaneous; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Exercise; Hemodynamics; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Physical Endurance | 1992 |
[Evaluation of tolerance during intravenous administration of low dose of isosorbide dinitrate in the treatment of unstable angina].
Topics: Acetylcysteine; Adult; Aged; Angina, Unstable; Blood Pressure; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Tachyphylaxis | 1992 |
Vasodilator properties of nitroglycerin and isosorbide dinitrate during cardiopulmonary bypass.
Topics: Adult; Aged; Blood Pressure; Blood Volume; Cardiopulmonary Bypass; Double-Blind Method; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Time Factors; Vascular Resistance; Vasodilator Agents | 1992 |
Efficacy of nifedipine and isosorbide mononitrate in combination with atenolol in stable angina.
Topics: Aged; Angina Pectoris; Atenolol; Blood Pressure; Double-Blind Method; Drug Combinations; Exercise Test; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Nitroglycerin; Prospective Studies | 1991 |
Comparative evaluation of intravenous isosorbide dinitrate and nitroglycerin in patients with acute myocardial infarction.
Topics: Aged; Arrhythmias, Cardiac; Blood Pressure; Female; Heart Rate; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Myoglobin; Nitroglycerin | 1991 |
[Transdermal nitroglycerin in stable effort angina. I. Therapeutic effect and duration of the action of a single dose. Comparison with placebo and isosorbide dinitrate].
Topics: Administration, Cutaneous; Administration, Oral; Aged; Angina Pectoris; Blood Pressure; Double-Blind Method; Exercise Test; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Placebos | 1991 |
[Comparative evaluation of the effectiveness of using peripheral vasodilators in the treatment of patients with acute myocardial infarction complicated by left-ventricular failure].
Topics: Adult; Aged; Cardiomyopathy, Dilated; Drug Evaluation; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Vasodilator Agents; Ventricular Function, Left | 1991 |
[Prolonged action nitrates in stable angina pectoris].
Topics: Administration, Cutaneous; Angina Pectoris; Delayed-Action Preparations; Double-Blind Method; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Tablets | 1991 |
The day-long antianginal effectiveness of nitroglycerin patches. A double-blind study using dose-titration.
Topics: Administration, Cutaneous; Aged; Angina Pectoris; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Evaluation Studies as Topic; Exercise; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Time Factors | 1991 |
[Nitrate tolerance measured by exercise test. Comparison of 2 preparations].
Topics: Aged; Angina Pectoris; Drug Tolerance; Exercise Test; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin | 1991 |
Anti-anginal therapy and quality of life. A comparison of the effects of transdermal nitroglycerin and long-acting oral nitrates.
Topics: Administration, Cutaneous; Adult; Aged; Angina Pectoris; Double-Blind Method; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Quality of Life; Time Factors | 1991 |
Comparative evaluation of a new formulation of isosorbide dinitrate oral spray and sublingual nitroglycerin tablets.
Topics: Administration, Oral; Administration, Sublingual; Aerosols; Chemistry, Pharmaceutical; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Randomized Controlled Trials as Topic; Tablets; Time Factors | 1990 |
Long-term haemodynamic effects of isosorbide 5-mononitrate in patients with cirrhosis and portal hypertension.
Topics: Administration, Oral; Aged; Blood Pressure; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver; Liver Cirrhosis; Male; Middle Aged; Nitroglycerin; Placebos; Time Factors | 1990 |
[Pharmacodynamics and results of a clinical trial of nitrogranulong, a new Soviet long-acting preparation of nitroglycerin].
Topics: Angina Pectoris; Animals; Cats; Delayed-Action Preparations; Electrocardiography; Humans; Isosorbide Dinitrate; Nitroglycerin; Rabbits | 1990 |
[Long-term nitrate therapy in coronary heart disease--loss of effect by developing tolerance].
Topics: Angina Pectoris; Coronary Disease; Dose-Response Relationship, Drug; Drug Tolerance; Electrocardiography; Exercise Test; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Long-Term Care; Male; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate | 1990 |
N-acetylcysteine modifies the acute effects of isosorbide-5-mononitrate in angina pectoris patients evaluated by exercise testing.
Topics: Acetylcysteine; Administration, Sublingual; Adult; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Random Allocation | 1989 |
Lack of effect of asymmetrical dosage timing of isosorbide-5-mononitrate on nitrate tolerance during long-term administration.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Patient Compliance; Random Allocation | 1989 |
[A comparison of 2 nitrates. 5-ISMN or nitroglycerin in patients with angina pectoris?].
Topics: Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Humans; Isosorbide Dinitrate; Nitroglycerin; Random Allocation | 1989 |
A randomised double-blind crossover study of isosorbide mononitrate and nifedipine retard in chronic stable angina.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Exercise Test; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nifedipine; Nitroglycerin; Random Allocation; Vasodilator Agents | 1989 |
Effects of diltiazem and isosorbide-5-mononitrate, alone and in combination, on patients with stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Headache; Heart Rate; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Random Allocation; Rest | 1989 |
Haemodynamic comparison of different routes of nitrate administration in postmyocardial infarction left ventricular failure.
Topics: Administration, Buccal; Administration, Cutaneous; Adult; Aged; Heart Failure; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Randomized Controlled Trials as Topic | 1989 |
[Development and status of nitrate therapy in East Germany].
Topics: Angina Pectoris; Delayed-Action Preparations; Dose-Response Relationship, Drug; Germany, East; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Propylene Glycols; Vasodilator Agents | 1989 |
[Long-term effect of organic nitrates in angina pectoris: dependence on the form of administration and mode of stress].
Topics: Administration, Oral; Administration, Sublingual; Adult; Aged; Angina Pectoris; Angioplasty, Balloon; Coronary Disease; Double-Blind Method; Electrocardiography; Exercise Test; Female; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Randomized Controlled Trials as Topic | 1989 |
The value of the left ventricular ejection fraction in the treatment of angina pectoris following acute myocardial infarction: a randomized double blind study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Cardiac Output; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Radionuclide Angiography; Random Allocation | 1989 |
Stable angina as a manifestation of ischemic heart disease: medical management.
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Calcium Channel Blockers; Cardiac Catheterization; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Exercise Test; Female; Humans; Hypertension; Isosorbide Dinitrate; Life Style; Male; Middle Aged; Nitroglycerin; Physical Exertion; Prognosis; Risk; Time Factors | 1985 |
[Randomized ergometric study of vasodilators combined with betablockaders].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Kinetics; Male; Middle Aged; Molsidomine; Nifedipine; Nitroglycerin; Sydnones; Vasodilator Agents | 1986 |
Medical management of stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Body Weight; Calcium Channel Blockers; Cholesterol, Dietary; Clinical Trials as Topic; Coronary Artery Bypass; Dietary Fats; Humans; Isosorbide Dinitrate; Nitroglycerin; Physical Exertion; Smoking Prevention | 1987 |
Anti-anginal efficacy of a controlled-release formulation of isosorbide-5-mononitrate once daily in angina patients on chronic beta-blockade.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Random Allocation | 1988 |
Transdermal glyceryl trinitrate patches (Transiderm-Nitro).
Topics: Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitroglycerin | 1986 |
Comparative clinical trial of isosorbide 5-mononitrate and sustained-release isosorbide dinitrate in ischaemic heart disease.
Topics: Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Delayed-Action Preparations; Double-Blind Method; Electrocardiography; Exercise Test; Female; Headache; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1986 |
[Clinico-pharmacological study of a new Russian anti-angina preparation dinitrosorbilong].
Topics: Administration, Oral; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Coronary Vessels; Drug Implants; Exercise Test; Gingiva; Humans; Isosorbide Dinitrate; Nitroglycerin | 1986 |
Some issues concerning transdermal nitroglycerin patches.
Topics: Administration, Topical; Angina Pectoris; Clinical Trials as Topic; Drug Administration Schedule; Humans; Isosorbide Dinitrate; Nifedipine; Nitroglycerin; Vasodilator Agents | 1986 |
Comparison of transdermal nitrate and isosorbide dinitrate in chronic stable angina.
Topics: Administration, Oral; Administration, Topical; Adult; Angina Pectoris; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Exercise Test; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1986 |
Recent developments in nitrate therapy of ischaemic heart disease.
Topics: Administration, Cutaneous; Angina Pectoris; Clinical Trials as Topic; Hemodynamics; Humans; Isosorbide Dinitrate; Kinetics; Nitroglycerin | 1987 |
[Dose-response relationship of nitrate therapy of angina pectoris].
Topics: Administration, Cutaneous; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1986 |
Hemodynamic effects of intravenous isosorbide dinitrate and nitroglycerine in acute myocardial infarction and elevated pulmonary artery wedge pressure.
Topics: Aged; Cardiac Catheterization; Drug Administration Schedule; Female; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Pulmonary Wedge Pressure; Random Allocation | 1987 |
[Hemodynamic and anti-angina effects of transdermal nitroglycerin after acute and chronic administration. Additive effect of sublingual isosorbide dinitrate].
Topics: Administration, Cutaneous; Administration, Oral; Angina Pectoris; Double-Blind Method; Drug Synergism; Exercise Test; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Random Allocation | 1986 |
Antianginal efficacy and tolerability of 50 mg sustained-release isosorbide 5-mononitrate in an open twelve-month observation study.
Topics: Adult; Aged; Angina Pectoris; Delayed-Action Preparations; Drug Therapy, Combination; Drug Tolerance; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1987 |
Controlled study of the haemodynamic effects of isosorbide 5-mononitrate in acute myocardial infarction.
Topics: Acute Disease; Administration, Oral; Aged; Female; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin | 1987 |
[Transdermal therapy of stable angina pectoris. Comparison of 2 different transdermal systems].
Topics: Administration, Cutaneous; Angina Pectoris; Clinical Trials as Topic; Electrocardiography; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1987 |
Effect of intravenous isosorbide dinitrate versus nitroglycerin on elevated pulmonary arterial wedge pressure during acute myocardial infarction.
Topics: Aged; Clinical Trials as Topic; Drug Evaluation; Female; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Pulmonary Wedge Pressure; Random Allocation | 1988 |
The methodological and clinical aspects of the placebo effect in angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Evaluation Studies as Topic; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Personality Inventory; Placebos; Tablets | 1988 |
Control of perioperative hypertension during coronary artery surgery. A randomised double-blind study comparing isosorbide dinitrate and nitroglycerin.
Topics: Coronary Artery Bypass; Double-Blind Method; Female; Humans; Hypertension; Intraoperative Complications; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Postoperative Complications; Pulmonary Wedge Pressure; Random Allocation | 1988 |
Assessment of dermal glyceryl trinitrate and isosorbide dinitrate for patients with angina pectoris.
Topics: Administration, Topical; Adult; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Headache; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Time Factors | 1985 |
[Transcutaneous application of nitroglycerin and isosorbide dinitrate versus placebo: effect in myocardial ischemia].
Topics: Administration, Topical; Aged; Angina Pectoris; Coronary Disease; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Ointments | 1985 |
Tolerance to the hemodynamic and antianginal effects of the organic nitrates.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin | 1985 |
Isosorbide dinitrate and nifedipine in variant angina pectoris.
Topics: Angina Pectoris, Variant; Clinical Trials as Topic; Coronary Vasospasm; Coronary Vessels; Double-Blind Method; Drug Therapy, Combination; Humans; Isosorbide Dinitrate; Nifedipine; Nitroglycerin; Prospective Studies; Vasodilation | 1985 |
The role of isosorbide dinitrate in the treatment of perioperative hypertension.
Topics: Clinical Trials as Topic; Coronary Artery Bypass; Double-Blind Method; Humans; Hypertension; Infusions, Parenteral; Isosorbide Dinitrate; Nitroglycerin; Nitroprusside; Preoperative Care | 1985 |
[4 different nitrate preparations with regard to the possible development of tolerance in long-term treatment].
Topics: Administration, Oral; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; Delayed-Action Preparations; Drug Tolerance; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Isosorbide Dinitrate; Long-Term Care; Male; Middle Aged; Myocardial Contraction; Nitroglycerin | 1985 |
Randomized crossover trial of isosorbide mononitrate (Elantan 20) and slow-release glyceryl trinitrate in the treatment of angina pectoris.
Topics: Administration, Oral; Aged; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Physical Exertion; Random Allocation; Time Factors | 1985 |
Prophylactic therapy of angina pectoris with organic nitrates: relationship of drug efficacy and clinical experimental design.
Topics: Angina Pectoris; Clinical Trials as Topic; Erythrityl Tetranitrate; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Placebos; Research Design; Time Factors | 1973 |
Effects of alprenolol and isosorbide dinitrate in angina pectoris. A comparative study with methodological considerations.
Topics: Activities of Daily Living; Adult; Aged; Alprenolol; Angina Pectoris; Electrocardiography; Female; Furans; Heart Function Tests; Humans; Isosorbide Dinitrate; Male; Methods; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin; Physical Exertion; Placebos; Vasodilator Agents | 1973 |
The long-acting hemodynamic effects of isosorbide dinitrate.
Topics: Angina Pectoris; Blood Pressure; Cardiac Output; Cardiac Volume; Exercise Test; Furans; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Placebos; Time Factors; Vascular Resistance; Vasodilator Agents | 1972 |
[The effect of five different long-acting nitroglycerine derivatives on angina pectoris].
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Electrocardiography; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Phenobarbital; Physical Exertion; Placebos; Vasodilator Agents | 1972 |
Hemodynamic response of oral long-acting nitrates: evidence of gastrointestinal absorption.
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Blood Flow Velocity; Clinical Trials as Topic; Coronary Disease; Delayed-Action Preparations; Female; Fingers; Furans; Humans; Intestinal Absorption; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin; Placebos; Plethysmography; Pulse; Tablets; Vasodilator Agents | 1972 |
The therapeutic role of coronary vasodilators: glyceryl trinitrate, isosorbide dinitrate, and pentaerythritol tetranitrate.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Electrocardiography; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrites; Nitroglycerin; Pentaerythritol Tetranitrate; Physical Exertion | 1966 |
Stress tests and the evaluation of anti-anginal drugs.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Electrocardiography; Erythrityl Tetranitrate; Evaluation Studies as Topic; Exercise Test; Heart; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate | 1967 |
Propranolol combined with isosorbide dinitrate versus placebo in angina pectoris.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Drug Synergism; Electrocardiography; Exercise Test; Furans; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Physical Exertion; Placebos; Propranolol | 1969 |
Sublingual isosorbide dinitrate therapy versus sublingual acebo in angina pectoris.
Topics: Administration, Oral; Adult; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Furans; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Physical Exertion; Placebos | 1970 |
Evaluation of nitroglycerin in angina in patients on isosorbide dinitrate.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Furans; Heart; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Placebos | 1970 |
Therapy of angina pectoris with propranolol and long-acting nitrates.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Electrocardiography; Exercise Test; Female; Furans; Heart Rate; Humans; Ischemia; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Placebos; Propranolol; Valsalva Maneuver; Vasodilator Agents | 1969 |
Therapy of angina pectoris with propranolol and long-acting nitrates.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Electrocardiography; Exercise Test; Female; Furans; Heart Function Tests; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Placebos; Propranolol | 1969 |
Anti anginal drugs, their evaluation by double blind trial.
Topics: Adult; Aged; Angina Pectoris; Erythrityl Tetranitrate; Female; Humans; Isosorbide Dinitrate; Male; Mannitol; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Placebos; Vasodilator Agents; Verapamil | 1970 |
The effects of chewable isosorbide dinitrate in coronary insufficiency. A report on exercise electrocardiograms in 13 patients.
Topics: Administration, Oral; Aged; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Electrocardiography; Exercise Test; Female; Furans; Heart; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Placebos | 1971 |
Clinical and circulatory effects of isosorbide dinitrate. Comparison with nitroglycerin.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Drug Synergism; Electrocardiography; Furans; Heart; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Middle Aged; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption; Physical Exertion; Placebos; Time Factors | 1971 |
Quantitative angiography: the measurement of coronary vasomobility in the intact animal and man.
Topics: Administration, Oral; Adult; Angina Pectoris; Angiocardiography; Animals; Cineangiography; Clinical Trials as Topic; Coronary Disease; Coronary Vessels; Dogs; Elasticity; Female; Furans; Humans; Isosorbide Dinitrate; Male; Methods; Middle Aged; Nitrates; Nitroglycerin; Placebos; Sorbitol; Vasodilator Agents | 1971 |
Intravenous nitroglycerin in the treatment of spontaneous angina pectoris: a prospective, randomized trial.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Female; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Prospective Studies | 1983 |
[Long-term effect of a new delayed-action nitroglycerin compared to isosorbide dinitrate. Double-blind hemodynamic study].
Topics: Adult; Aged; Cardiac Output; Clinical Trials as Topic; Coronary Disease; Delayed-Action Preparations; Double-Blind Method; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pulmonary Wedge Pressure; Stroke Volume; Time Factors | 1983 |
[8-hour hemodynamic study of 2 sustained-release nitrate derivatives. Comparative double-blind study against placebo].
Topics: Administration, Oral; Delayed-Action Preparations; Double-Blind Method; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Placebos; Pulmonary Wedge Pressure; Time Factors | 1983 |
Intra-individual comparison of the action of equal doses of isosorbide-5-endomononitrate, slow-release isosorbide dinitrate and placebo in patients with coronary heart disease.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Electrocardiography; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin | 1983 |
[Randomized double-blind comparative study: glycerol trinitrate and isosorbide mononitrate].
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1983 |
Hemodynamic and hormonal response to induced hypotension with isosorbide dinitrate and nitroglycerin during anesthesia.
Topics: Adolescent; Adult; Anesthesia; Blood Pressure; Catecholamines; Hemodynamics; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Oxygen Consumption; Renin | 1983 |
Tolerance development during isosorbide dinitrate treatment: can it be circumvented?
Topics: Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Drug Tolerance; Electrocardiography; Humans; Isosorbide Dinitrate; Nitroglycerin; Random Allocation | 1983 |
[Nitrate tolerance: pro and con].
Topics: Angina Pectoris; Cardiac Output; Clinical Trials as Topic; Drug Administration Schedule; Drug Tolerance; Headache; Heart Rate; Humans; Hypertension; Isosorbide Dinitrate; Long-Term Care; Nitrates; Nitroglycerin | 1984 |
Nitrate tolerance.
Topics: Angina Pectoris; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Long-Term Care; Male; Nitroglycerin | 1984 |
[Development of tolerance with regard to the anti-ischemic effect of isosorbide dinitrate in regular multiple daily administration].
Topics: Angina Pectoris; Blood Pressure; Coronary Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug Tolerance; Electrocardiography; Exercise Test; Heart Rate; Humans; Isosorbide Dinitrate; Long-Term Care; Nitroglycerin | 1984 |
Nitrate cross-tolerance: effect of sublingual isosorbide dinitrate and nitroglycerin during sustained nitrate therapy.
Topics: Aged; Angina Pectoris; Blood Pressure; Drug Therapy, Combination; Drug Tolerance; Exercise Test; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Mouth Floor; Nitroglycerin; Random Allocation | 1984 |
Effects of isosorbide dinitrate spray on central hemodynamics. Comparison with sublingual glyceryl trinitrate and isosorbide dinitrate.
Topics: Administration, Topical; Adult; Aerosols; Aged; Blood Pressure; Cheek; Female; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Mouth Floor; Mouth Mucosa; Myocardial Infarction; Nitroglycerin; Tablets; Time Factors | 1984 |
[Dynamics of critical stenosis in patients with unstable angina pectoris].
Topics: Angina Pectoris; Angina, Unstable; Coronary Angiography; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Isosorbide Dinitrate; Molsidomine; Myocardial Infarction; Nifedipine; Nitroglycerin; Sydnones | 1984 |
Treatment of coronary heart disease with isosorbide mononitrate ('Elantan' 20).
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1984 |
Tolerance to the circulatory effects of oral isosorbide dinitrate. Rate of development and cross-tolerance to glyceryl trinitrate.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Drug Tolerance; Female; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1980 |
[Comparative examinations of the effectiveness of Molsidomin and nitrates in angina pectoris].
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Molsidomine; Morpholines; Nitroglycerin; Oxadiazoles; Sydnones | 1980 |
[Comparative study of three oral nitrate derivatives. A hemodynamic assessment in 10 patients with chronic heart failure (author's transl)].
Topics: Administration, Oral; Adult; Blood Pressure; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Pulmonary Artery | 1980 |
[Comparative study of the effectiveness of sustac and nitrosorbid treatment of exertion-induced angina pectoris].
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Physical Exertion; Vasodilator Agents | 1981 |
Treadmill exercise protocols to demonstrate effectiveness of nitrate drugs in relief of angina pectoris; duration of action and degree of functional enhancement.
Topics: Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Erythrityl Tetranitrate; Exercise Test; Humans; Isosorbide Dinitrate; Nitroglycerin | 1981 |
Randomized double-blind comparison of nifedipine and isosorbide dinitrate in patients with coronary arterial spasm.
Topics: Adult; Aged; Angina Pectoris; Angiocardiography; Clinical Trials as Topic; Coronary Vasospasm; Double-Blind Method; Drug Evaluation; Electrocardiography; Female; Headache; Heart Ventricles; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Nitroglycerin; Pyridines; Random Allocation | 1982 |
Effects of organic nitrate vasodilators on platelet function before and after cardiopulmonary bypass.
Topics: Adult; Aged; Blood Platelets; Cardiopulmonary Bypass; Double-Blind Method; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Platelet Aggregation; Vasodilator Agents | 1995 |
Interaction of intravenous heparin and organic nitrates in acute ischemic syndromes.
Topics: Acute Disease; Aged; Analysis of Variance; Anticoagulants; Antithrombin III; Drug Interactions; Female; Fibrinolytic Agents; Heparin; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Linear Models; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Partial Thromboplastin Time; Prospective Studies; Syndrome; Vasodilator Agents | 1995 |
Antianginal effect of transdermal nitroglycerin and oral nitrates given for 24 hours a day in 2,456 patients with stable angina pectoris. The Italian Multicenter Study.
Topics: Administration, Cutaneous; Administration, Oral; Aged; Angina Pectoris; Chronic Disease; Circadian Rhythm; Drug Tolerance; Female; Humans; Isosorbide Dinitrate; Italy; Male; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilator Agents | 1995 |
The effect of intravenous nitroglycerin therapy on infarct size in patients with acute myocardial infarction.
Topics: Administration, Oral; Adult; Aged; Creatine Kinase; Female; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Streptokinase | 1995 |
Which drug to choose for stable angina pectoris: a comparative study between bisoprolol and nitrates.
Topics: Adult; Aged; Angina Pectoris; Bisoprolol; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Exercise Test; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Treatment Outcome | 1995 |
Short and long-acting oral nitrates for stable angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Delayed-Action Preparations; Drug Therapy, Combination; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; United States; United States Food and Drug Administration; Vasodilator Agents | 1994 |
Ointments and transdermal nitroglycerin patches for stable angina pectoris.
Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Angina Pectoris; Delayed-Action Preparations; Drug Delivery Systems; Drug Tolerance; Exercise; Humans; Isosorbide Dinitrate; Nitroglycerin; Ointments; Product Surveillance, Postmarketing | 1994 |
[Effect of low-dosage intravenous nitrate therapy on the anticoagulant effect of heparin].
Topics: Aged; Aged, 80 and over; Coronary Disease; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Heparin; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Partial Thromboplastin Time; Single-Blind Method | 1994 |
[Hemodynamics effects of continuous infusion of molsidomine and nitrates and subsequent oral medication in therapy of acute myocardial infarct].
Topics: Administration, Oral; Aged; Aged, 80 and over; Female; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Molsidomine; Myocardial Infarction; Nitrates; Nitroglycerin; Vasodilator Agents | 1994 |
Isosorbide dinitrate does not interfere with heparin anticoagulation: a placebo-controlled comparison with nitroglycerin in patients scheduled for coronary artery surgery.
Topics: Adult; Aged; Animals; Blood Coagulation; Coronary Artery Bypass; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Factor Xa Inhibitors; Female; Heparin; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Placebos; Swine; Whole Blood Coagulation Time | 1994 |
The utility of Nitroderm TTS in angina pectoris: long-term treatment after switching from long-acting oral isosorbide dinitrate.
Topics: Administration, Cutaneous; Administration, Oral; Administration, Sublingual; Aged; Angina Pectoris; Drug Administration Schedule; Electrocardiography; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Prospective Studies; Treatment Outcome | 1994 |
Influence of glyceryl trinitrate on venous and arterial effects of chronic, asymmetric isosorbide dinitrate treatment in patients with ischemic heart disease.
Topics: Aged; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Rest | 1994 |
The effect of different nitrate preparations on plasma heparin concentrations and the activated partial thromboplastin time.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Antithrombin III; Female; Heparin; Heparin Antagonists; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Partial Thromboplastin Time | 1994 |
Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. A randomized, double-blind, cross-over study. The Swedish Multicentre Group.
Topics: Analysis of Variance; Angina Pectoris; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Exercise Test; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Vasodilator Agents | 1994 |
Pulmonary vascular effects of trinitroglycerin and isosorbide dinitrate after cardiopulmonary bypass.
Topics: Adult; Aged; Blood Pressure; Cardiopulmonary Bypass; Coronary Artery Bypass; Double-Blind Method; Hemodynamics; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Postoperative Period; Pulmonary Artery; Vascular Resistance | 1993 |
Pulmonary vascular effects of nitroglycerin and isosorbide dinitrate in patients with end-stage cardiomyopathies.
Topics: Adult; Blood Pressure; Cardiac Output; Cardiomyopathies; Cross-Over Studies; Double-Blind Method; Female; Heart Transplantation; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pulmonary Artery; Pulmonary Circulation; Stroke Volume; Vascular Resistance; Vasodilator Agents | 1996 |
Long-term nitrate treatment increases cardiac events in patients with healed myocardial infarction. Secondary Prevention Group.
Topics: Aged; Death, Sudden, Cardiac; Double-Blind Method; Drug Tolerance; Female; Heart Failure; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin; Odds Ratio; Recurrence; Time Factors; Vasodilator Agents | 1996 |
Counterregulatory responses: sustained-release isosorbide-5-mononitrate versus transdermal nitroglycerin.
Topics: Administration, Cutaneous; Adult; Blood Pressure; Body Weight; Catecholamines; Delayed-Action Preparations; Drug Tolerance; Heart Rate; Hematocrit; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Renin; Single-Blind Method; Sodium; Vasodilator Agents | 1996 |
Pain scoring--a method for assessing acute antianginal therapy comparison of the response to acute sublingual administration of an isosorbide dinitrate tablet, isosorbide dinitrate spray and nitroglycerin spray in unstable angina.
Topics: Administration, Inhalation; Administration, Oral; Administration, Sublingual; Adult; Aged; Aged, 80 and over; Angina, Unstable; Feasibility Studies; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pain; Pain Measurement; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Vasodilator Agents | 1998 |
A comparative study of eccentric and concentric coronary stenosis vasomotion in patients with Prinzmental's variant angina and patients with stable angina pectoris.
Topics: Adult; Angina Pectoris; Angina Pectoris, Variant; Blood Pressure; Chronic Disease; Coronary Angiography; Coronary Vasospasm; Ergonovine; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Muscle, Smooth, Vascular; Nitroglycerin; Vasodilator Agents; Vasomotor System | 1998 |
Nitrate induced coronary vasodilatation: differential effects of sublingual application by capsule or spray.
Topics: Acute Disease; Administration, Inhalation; Administration, Sublingual; Adult; Aerosols; Aged; Analysis of Variance; Capsules; Coronary Angiography; Coronary Disease; Female; Humans; Injections, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Vasodilator Agents | 1998 |
Dissociation of vascular tolerance and plasma norepinephrine adjustment during long-term nitrate therapy in human coronary arteries.
Topics: Aged; Angina Pectoris; Coronary Angiography; Coronary Vessels; Drug Tolerance; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Norepinephrine; Vasodilator Agents | 1999 |
Sildenafil citrate potentiates the hypotensive effects of nitric oxide donor drugs in male patients with stable angina.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Oral; Aged; Angina Pectoris; Blood Pressure; Contraindications; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide Donors; Nitroglycerin; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones | 2000 |
Nitroglycerin is preferable to diltiazem for prevention of coronary bypass conduit spasm.
Topics: Coronary Artery Bypass; Costs and Cost Analysis; Creatine Kinase; Diltiazem; Female; Humans; Isosorbide Dinitrate; Length of Stay; Male; Middle Aged; Nitroglycerin; Postoperative Complications; Prospective Studies; Radial Artery; Spasm; Vasodilator Agents | 2000 |
Headache characteristics during the development of tolerance to nitrates: pathophysiological implications.
Topics: Administration, Oral; Adult; Cross-Over Studies; Double-Blind Method; Drug Tolerance; Female; Headache; Humans; Isosorbide Dinitrate; Male; Middle Aged; Migraine Disorders; Nitroglycerin; Severity of Illness Index; Vasodilator Agents | 2000 |
Potential efficacy of nitric oxide for cervical ripening in pregnancy at term.
Topics: Cervical Ripening; Dinoprostone; Female; Humans; Isosorbide Dinitrate; Nitric Oxide Donors; Nitroglycerin; Pregnancy; Vasodilator Agents | 2000 |
Topical application of nitrates onto the papilla of Vater: manometric and clinical results.
Topics: Administration, Topical; Adolescent; Adult; Ampulla of Vater; Catheterization; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis; Double-Blind Method; Female; Humans; Isosorbide Dinitrate; Male; Manometry; Middle Aged; Nitroglycerin; Peristalsis; Probability; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric; Vasodilator Agents | 2001 |
Vasovagal susceptibility to nitrate or isoproterenol head-up tilt.
Topics: Adolescent; Adult; Aged; Autonomic Nervous System; Cross-Over Studies; Disease Susceptibility; Female; Heart Rate; Humans; Isoproterenol; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Posture; Sympathomimetics; Syncope, Vasovagal; Tilt-Table Test; Vasodilator Agents | 2001 |
A double-blind, parallel-group study of amlodipine versus long-acting nitrate in the management of elderly patients with stable angina.
Topics: Aged; Aged, 80 and over; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Double-Blind Method; Edema; Exercise Test; Exercise Tolerance; Female; Headache; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Quality of Life; Time Factors; Vasodilator Agents | 2001 |
Local effect of transdermal isosorbide dinitrate ointment on hand vein diameter.
Topics: Administration, Cutaneous; Adult; Blood Vessels; Cross-Over Studies; Double-Blind Method; Hand; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Ointments; Phenylephrine; Phlebotomy; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
[Comparative evaluation of the clinical effectiveness and the adverse effects of three different forms of nitrates in high oral doses in patients with stable angina pectoris].
Topics: Angina Pectoris; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Treatment Outcome; Vasodilator Agents | 2002 |
[Quality of life and angina pectoris. Comparison of the effects of 2 nitrate derivatives administered discontinuously: transdermal 10 mg nitroglycerine patch (12 hours) and long-acting oral 40 mg isosorbide-5-mononitrate (once a day)].
Topics: Administration, Cutaneous; Administration, Oral; Angina Pectoris; Cross-Over Studies; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Quality of Life; Vasodilator Agents | 2001 |
Glyceryl trinitrate patches as an alternative to isosorbide dinitrate spray in the treatment of chronic painful diabetic neuropathy.
Topics: Administration, Cutaneous; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pain; Vasodilator Agents | 2003 |
[Nitrates in therapy of effort angina in hypotensive patients].
Topics: Angina Pectoris; Cross-Over Studies; Exercise Test; Humans; Hypotension; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Nitrates; Nitric Oxide Donors; Nitroglycerin; Placebos; Time Factors; Vasodilator Agents | 2003 |
Anti-ischaemic response to sublingual nitroglycerin during oral administration of isosorbide dinitrate in patients with stable angina pectoris: when does cross-tolerance occur?
Topics: Adult; Angina Pectoris; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide Donors; Nitroglycerin | 2004 |
Withdrawal of intravenous glyceryl trinitrate: absence of rebound phenomena with transition to oral isosorbide dinitrate.
Topics: Administration, Oral; Aged; Angina Pectoris; Angina, Unstable; Cohort Studies; Coronary Disease; Coronary Vessels; Drug Tolerance; Female; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Vasoconstriction; Vasodilator Agents | 2005 |
Nitroester drug's effects and their antagonistic effects against morphine on human sphincter of Oddi motility.
Topics: Adult; Aged; Analgesics, Opioid; Drug Interactions; Female; Gastrointestinal Motility; Humans; Isosorbide Dinitrate; Male; Middle Aged; Morphine; Nitroglycerin; Pentaerythritol Tetranitrate; Sphincter of Oddi; Vasodilator Agents | 2005 |
Preservation of platelet responsiveness to nitroglycerine despite development of vascular nitrate tolerance.
Topics: Aged; Angina Pectoris; Blood Platelets; Cross-Over Studies; Delayed-Action Preparations; Drug Resistance; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide; Nitroglycerin; Platelet Aggregation; Vasodilator Agents | 2005 |
[Clinical study on "sini" decoction on treating stenocardia for coronary heart disease].
Topics: Aged; Coronary Disease; Drugs, Chinese Herbal; Electrocardiography; Female; Heart Function Tests; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Oxygen Consumption; Phytotherapy; Plants, Medicinal; Vasodilator Agents; Yang Deficiency | 2005 |
Double-blind, multicenter, active-controlled, randomized clinical trial to assess the safety and efficacy of orally administered nicorandil in patients with stable angina pectoris in China.
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Anti-Arrhythmia Agents; China; Double-Blind Method; Exercise; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nicorandil; Nitroglycerin; Vasodilator Agents | 2007 |
Pentaerythrityl tetranitrate and nitroglycerin, but not isosorbide mononitrate, prevent endothelial dysfunction induced by ischemia and reperfusion.
Topics: Adult; Double-Blind Method; Endothelium, Vascular; Humans; Ischemic Preconditioning; Isosorbide Dinitrate; Male; Nitroglycerin; Pentaerythritol Tetranitrate; Reperfusion Injury; Vasodilator Agents | 2007 |
Topical anal fissure treatment: placebo-controlled study of mononitrate and trinitrate therapies.
Topics: Administration, Topical; Adolescent; Adult; Aged; Female; Fissure in Ano; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Placebos; Treatment Outcome; Vasodilator Agents | 2009 |
Comparison of a shortened isosorbide dinitrate-potentiated head-up tilt testing with the conventional protocol: tolerance and diagnostic accuracy.
Topics: Adult; Diagnostic Errors; Female; Humans; Isoproterenol; Isosorbide Dinitrate; Male; Nitroglycerin; Patient Satisfaction; Sensitivity and Specificity; Syncope, Vasovagal; Tilt-Table Test; Vasodilator Agents; Young Adult | 2012 |
A randomized phase II study of irinotecan plus cisplatin versus irinotecan plus capecitabine with or without isosorbide-5-mononitrate in advanced non-small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Carcinoma, Non-Small-Cell Lung; Cisplatin; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Isosorbide Dinitrate; Lung Neoplasms; Male; Middle Aged; Nitroglycerin; Treatment Outcome | 2012 |
Nitrates and bone turnover (NABT) - trial to select the best nitrate preparation: study protocol for a randomized controlled trial.
Topics: Administration, Cutaneous; Administration, Sublingual; Age Factors; Biomarkers; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Chemistry, Pharmaceutical; Clinical Protocols; Female; Headache; Humans; Isosorbide Dinitrate; Middle Aged; Nitrates; Nitroglycerin; Ointments; Ontario; Postmenopause; Research Design; Tablets; Time Factors; Transdermal Patch; Treatment Outcome | 2013 |
[Autonomous pharmacodynamics of organic nitrates in patients with unstable angina].
Topics: Angina, Unstable; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Treatment Outcome; Vasodilator Agents | 2013 |
Impacts of nicorandil on infarct myocardium in comparison with nitrate: assessed by cardiac magnetic resonance imaging.
Topics: Aged; Biomarkers; Coronary Circulation; Coronary Vessels; Creatine Kinase, MB Form; Edema, Cardiac; Female; Humans; Isosorbide Dinitrate; Japan; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction; Nicorandil; Nitroglycerin; Percutaneous Coronary Intervention; Pilot Projects; Predictive Value of Tests; Time Factors; Treatment Outcome; Vasodilator Agents | 2016 |
393 other study(ies) available for isosorbide dinitrate and nitroglycerin
| Article | Year |
|---|---|
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
NO donors. Part 16: investigations on structure-activity relationships of organic mononitrates reveal 2-nitrooxyethylammoniumnitrate as a high potent vasodilator.
Topics: Nitrates; Nitric Oxide Donors; Quaternary Ammonium Compounds; Structure-Activity Relationship; Vasodilator Agents | 2007 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
[Conservative therapy of coronary disease].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Nitroglycerin; Vasodilator Agents; Verapamil | 1976 |
[Drug and surgical therapy of angina pectoris].
Topics: Adrenergic beta-Antagonists; Analgesics; Angina Pectoris; Coronary Artery Bypass; Germany, West; Hemodynamics; Humans; Isosorbide Dinitrate; Life Expectancy; Nitroglycerin; Physical Fitness; Prognosis | 1975 |
[General practicioner in face of angina pectoris (author's transl)].
Topics: Adrenergic beta-Antagonists; Amiodarone; Angina Pectoris; Diet, Reducing; Exercise Therapy; Family Practice; Humans; Isosorbide Dinitrate; Nitroglycerin; Perhexiline | 1977 |
The medical management of angina pectoris.
Topics: Adrenergic beta-Antagonists; Amyl Nitrite; Angina Pectoris; Delayed-Action Preparations; Humans; Isosorbide Dinitrate; Nitroglycerin; Posture | 1977 |
[Therapy of coronary heart disease].
Topics: Adrenergic beta-Antagonists; Blood Pressure; Calcium; Coronary Disease; Humans; Isosorbide Dinitrate; Nifedipine; Nitroglycerin; Phenethylamines; Risk; Smoking; Vasodilator Agents; Verapamil | 1977 |
Angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Humans; Isosorbide Dinitrate; Nifedipine; Nitroglycerin; Perhexiline | 1978 |
[2nd international nitrate symposium, Berlin 1978--abstracts (author's transl)].
Topics: Animals; Berlin; Congresses as Topic; Coronary Disease; Dogs; Humans; Isosorbide Dinitrate; Nitroglycerin | 1978 |
The treatment of angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Coronary Angiography; Humans; Isosorbide Dinitrate; Middle Aged; Nifedipine; Nitroglycerin; Perhexiline; Physical Exertion; Prenylamine; Verapamil | 1979 |
[Long-term therapy of coronary disease. Possibilities and limitations of conservative therapy].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium; Coronary Disease; Digitalis Glycosides; Humans; Isosorbide Dinitrate; Nitroglycerin | 1979 |
[Proceedings: Identification of reversible-asynergic myocardial regions by means of postextrasystolic potentiation (PESP) and application of nitrate].
Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Humans; Isosorbide Dinitrate; Methods; Myocardial Contraction; Nitroglycerin | 1975 |
[New nitrate indications].
Topics: Dihydralazine; Drug Combinations; Heart Diseases; Humans; Hydralazine; Isosorbide Dinitrate; Myocardial Infarction; Nitrates; Nitroglycerin; Nitroprusside; Phentolamine; Vasodilator Agents | 1978 |
Long-term outpatient vasodilator therapy of congestive heart failure. Consideration of agents at rest and during exercise.
Topics: Chronic Disease; Drug Therapy, Combination; Heart Failure; Heart Ventricles; Hemodynamics; Humans; Hydralazine; Isosorbide Dinitrate; Lupus Erythematosus, Systemic; Nitroglycerin; Physical Exertion; Prazosin; Pressure; Rest; Time Factors; Vasodilator Agents | 1978 |
Surgical approach for patients with unstable angina pectoris: role of the response to initial medical therapy and intraaortic balloon pumping in perioperative complications after aortocoronary bypass grafting.
Topics: Administration, Oral; Angina Pectoris; Assisted Circulation; Cardiac Catheterization; Coronary Artery Bypass; Female; Humans; Intra-Aortic Balloon Pumping; Isosorbide Dinitrate; Male; Myocardial Infarction; Nitroglycerin; Ointments; Postoperative Complications; Propranolol; Shock, Cardiogenic | 1978 |
[2. International Symposium on Nitrates; Berlin 1-3 June 1978. Nitrate-effect on the heart and circulation].
Topics: Angina Pectoris; Animals; Blood Circulation; Coronary Disease; Heart; Heart Failure; Humans; Isosorbide Dinitrate; Male; Myocardial Infarction; Nitrates; Nitroglycerin; Nitroprusside; Rats | 1978 |
[Peroral nitrate therapy in severe cardiac insufficiency following acute myocardial infarct].
Topics: Administration, Oral; Aged; Delayed-Action Preparations; Heart Failure; Humans; Isosorbide Dinitrate; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin | 1978 |
[Response of the arteriolar circulation evaluated by means of photoplethysmography after nitroderivatives].
Topics: Arterial Occlusive Diseases; Arteries; Arterioles; Blood Circulation; Erythrityl Tetranitrate; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Plethysmography | 1977 |
Nitrates and ectopic ventricular activity in mitral valve prolapse: clinical and experimental data.
Topics: Animals; Arrhythmias, Cardiac; Death, Sudden; Dogs; Electrocardiography; Electrophysiology; Heart Conduction System; Humans; Isosorbide Dinitrate; Mitral Valve Prolapse; Nitroglycerin; Rabbits | 1979 |
Medically refractory unstable angina pectoris. II. Hemodynamic and angiographic effects of intraaortic balloon counterpulsation.
Topics: Administration, Oral; Adult; Angina Pectoris; Angiocardiography; Assisted Circulation; Blood Pressure; Cardiac Catheterization; Cardiac Output; Female; Hemodynamics; Humans; Intra-Aortic Balloon Pumping; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Contraction; Nitroglycerin; Ointments; Propranolol; Pulmonary Circulation | 1979 |
Pharmacology update: anti-anginal agents.
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Nitroglycerin; Pentaerythritol Tetranitrate | 1979 |
[Glaucoma and vasodilating agents].
Topics: Glaucoma; Humans; Isosorbide Dinitrate; Nitroglycerin | 1979 |
[Effect of nitroglycerin and sorbonit on the dynamics of post-exercise changes of acid-base equilibrium].
Topics: Acid-Base Equilibrium; Adult; Coronary Disease; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Physical Exertion; Propranolol | 1979 |
[Use of nitro preparations in the acute period of myocardial infarct].
Topics: Acute Disease; Adult; Aged; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Vasodilator Agents | 1979 |
[Short-term action of trinitrine and dinitrate of isosorbitol on some cardiac parameters].
Topics: Carotid Arteries; Coronary Disease; Heart; Hemodynamics; Humans; Isosorbide Dinitrate; Nitroglycerin | 1978 |
[Effects on the systemic and coronary circulation of 2 nitrate derivatives, intravenous trinitrin and sublingual isosorbide dinitrate, administered during atrial pacing].
Topics: Administration, Oral; Adult; Aged; Blood Circulation; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Female; Humans; Injections, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Mouth Floor; Myocardium; Nitrites; Nitroglycerin | 1979 |
Effect of 2-nicotinamidethyl nitrate (SG 75) on coronary circulation.
Topics: Animals; Constriction, Pathologic; Coronary Circulation; Coronary Vessels; Diltiazem; Dogs; Heart Rate; Isosorbide Dinitrate; Ligation; Niacinamide; Nifedipine; Nitrates; Nitroglycerin; Papaverine; Vasodilator Agents; Verapamil | 1978 |
Effects of coronary vasodilator on cyclic nucleotides. The concentrations of cyclic AMP and cyclic GMP in canine coronary artery and left ventricular muscle following the administration of various coronary vasodilators.
Topics: Amyl Nitrite; Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Diltiazem; Dipyridamole; Dogs; Heart Ventricles; Isosorbide Dinitrate; Myocardium; Nifedipine; Nitroglycerin; Papaverine; Radioimmunoassay; Vasodilator Agents | 1979 |
Ventricular unloading in the management of heart disease: role of vasodilators. Part II.
Topics: Cardiomyopathy, Hypertrophic; Coronary Artery Bypass; Dosage Forms; Heart Diseases; Heart Failure; Heart Valve Diseases; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardial Contraction; Myocardial Infarction; Nitroglycerin; Nitroprusside; Postoperative Complications; Vasodilator Agents | 1977 |
Effects of coronary vasodilators on large and small coronary arteries of dogs.
Topics: Adenosine; Animals; Arteries; Coronary Circulation; Coronary Vessels; Dipyridamole; Dogs; Erythritol; In Vitro Techniques; Ischemia; Isosorbide Dinitrate; Nifedipine; Nitroglycerin; Vascular Resistance; Vasodilator Agents; Verapamil | 1977 |
The management of the patient with angina.
Topics: Angina Pectoris; Anticoagulants; Clofibrate; Coronary Artery Bypass; Diazepam; Digoxin; Humans; Isosorbide Dinitrate; Nitroglycerin; Oxprenolol; Perhexiline; Prenylamine; Propranolol; Verapamil | 1977 |
Prolonged salutary effects of isosorbide dinitrate and nitroglycerin ointment on regional left ventricular function.
Topics: Adult; Aged; Blood Pressure; Echocardiography; Female; Heart Rate; Heart Ventricles; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Contraction; Nitroglycerin; Ointments; Oxygen Consumption; Time Factors | 1977 |
Drug management of stable angina pectoris.
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Physical Exertion; Propranolol; Vasodilator Agents | 1977 |
Hemodynamic advantage of combined administration of hydralazine orally and nitrates nonparenterally in the vasodilator therapy of chronic heart failure.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Cardiac Output; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Hydralazine; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Vascular Resistance; Vasodilator Agents | 1977 |
Effects of long-term oral administration of isosorbide dinitrate on the antianginal response to nitroglycerin. Absence of nitrate cross-tolerance and self-tolerance shown by exercise testing.
Topics: Administration, Oral; Angina Pectoris; Blood Pressure; Delayed-Action Preparations; Drug Tolerance; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Isosorbide Dinitrate; Long-Term Care; Male; Middle Aged; Nitroglycerin; Oxygen Consumption; Time Factors | 1978 |
Medical management of angina pectoris.
Topics: Angina Pectoris; Humans; Hypnotics and Sedatives; Isosorbide Dinitrate; Nitroglycerin | 1977 |
Medical therapy of angina pectoris.
Topics: Angina Pectoris; Blood Pressure; Coronary Circulation; Erythrityl Tetranitrate; Heart Rate; Humans; Isosorbide Dinitrate; Myocardial Contraction; Myocardium; Nitroglycerin; Oxygen Consumption; Propranolol | 1977 |
Usefulness of long-acting nitrates in cardiovascular disease.
Topics: Cardiovascular Diseases; Coronary Disease; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Time Factors; Vasodilator Agents | 1978 |
Current clinical status of nitroglycerin and other nitrates.
Topics: Angina Pectoris; Heart Diseases; Heart Failure; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Nitroprusside | 1978 |
[Action of nitrates on the nature of mechanical and electrical activity of the rat aorta and portal vein].
Topics: Animals; Aorta, Thoracic; Electrophysiology; Ferricyanides; Isosorbide Dinitrate; Male; Muscle, Smooth; Nitroglycerin; Nitroprusside; Portal Vein; Rats; Vasodilation | 1977 |
Letter: Natural history of angina pectoris.
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Nitroglycerin; Prognosis; Propranolol; Risk | 1975 |
Editorial: Antiangina or antimyocaridal ischemia drugs.
Topics: Angina Pectoris; Coronary Disease; Drug Evaluation; Electrocardiography; Exercise Test; Heart; Humans; Isosorbide Dinitrate; Nitroglycerin | 1975 |
Effectiveness of isosorbide dinitrate and nitroglycerin in relieving angina pectoris during uninterrupted exercise.
Topics: Administration, Oral; Aged; Angina Pectoris; Drug Evaluation; Electrocardiography; Exercise Test; Female; Heart; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Physical Exertion; Time Factors | 1975 |
[Long-term action of nitrites in coronary heart disease (author's transl)].
Topics: Blood Pressure; Cardiac Output; Coronary Disease; Heart Rate; Humans; Isosorbide Dinitrate; Nitrites; Nitroglycerin; Pulmonary Artery; Time Factors | 1975 |
Comparative vasodilator effects of nitroglycerin, pentaerythritol trinitrate and biometabolites, and other organic nitrates.
Topics: Animals; Coronary Vessels; Dogs; Drug Interactions; Female; Hemodynamics; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin; Propylene Glycols; Regional Blood Flow; Tachyphylaxis; Vasodilator Agents | 1975 |
Intramyocardial diversion of coronary blood flow: effects of isoproterenol-induced subendocardial ischemia.
Topics: Adult; Aged; Animals; Child; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Drug Antagonism; Electrocardiography; Endocardium; Female; Humans; Ischemia; Isoproterenol; Isosorbide Dinitrate; Male; Middle Aged; Myocardium; Nitroglycerin; Oxygen; Propranolol; Rats; Regional Blood Flow; Retrospective Studies; Sotalol | 1975 |
Drugs for prophylaxis of angina pectoris.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Drug Administration Schedule; Erythrityl Tetranitrate; Humans; Isosorbide Dinitrate; Nitroglycerin; Propranolol | 1975 |
Isosorbide dinitrate. Effect on the vasodilator response to nitroglycerin.
Topics: Administration, Oral; Adult; Arteries; Blood Pressure; Blood Volume; Drug Interactions; Hemodynamics; Humans; Injections, Intra-Arterial; Isosorbide Dinitrate; Leg; Middle Aged; Nitroglycerin; Phentolamine; Vascular Resistance; Veins | 1975 |
The gastrointestinal absorption of organic nitrates.
Topics: Administration, Oral; Animals; Delayed-Action Preparations; Dogs; Humans; Intestinal Absorption; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Rabbits; Rats; Tablets | 1975 |
[New aspects of the treatment of left ventricular failure: Nitroglycerin (author's transl)].
Topics: Acute Disease; Administration, Oral; Aged; Arteries; Blood Pressure; Cardiac Catheterization; Cardiac Output; Chronic Disease; Coronary Disease; Heart Failure; Heart Ventricles; Humans; Injections, Intravenous; Isosorbide Dinitrate; Male; Myocardial Infarction; Nitroglycerin; Pulmonary Edema; Tongue | 1975 |
[Proceedings: The effect of nitrates on the systemic circulation and the myocardial oxygen consumption].
Topics: Blood Circulation; Coronary Disease; Coronary Vessels; Humans; Isosorbide Dinitrate; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption; Regional Blood Flow | 1975 |
Vasodilator therapy for chronic left ventricular failure.
Topics: Adult; Aged; Chronic Disease; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Nitroprusside; Vasodilator Agents | 1976 |
Drug therapy in the treatment of angina pectoris.
Topics: Angina Pectoris; Heart Rate; Humans; Isosorbide Dinitrate; Myocardium; Nitroglycerin; Oxygen Consumption; Patient Education as Topic; Propranolol | 1976 |
Peripheral vasodilators in the treatment of cardiac failure.
Topics: Blood Pressure; Cardiac Output; Coronary Circulation; Dose-Response Relationship, Drug; Heart Failure; Humans; Isosorbide Dinitrate; Lactates; Mitral Valve Insufficiency; Myocardial Infarction; Myocardium; Nitroglycerin; Nitroprusside; Oxygen Consumption; Vascular Resistance; Vasodilator Agents | 1976 |
Letter: Effectiveness of isosorbide dinitrate and nitroglycerin in relieving angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Drug Evaluation; Drug Therapy, Combination; Humans; Isosorbide Dinitrate; Nitroglycerin; Time Factors | 1976 |
Letter: Anginal nitrate stability.
Topics: Drug Stability; Isosorbide Dinitrate; Nitroglycerin | 1976 |
Letter: Cardiac failure.
Topics: Heart Failure; Humans; Isosorbide Dinitrate; Nitrites; Nitroglycerin | 1976 |
Long-acting nitrates in the treatment of angina pectoris.
Topics: Angina Pectoris; Delayed-Action Preparations; Erythrityl Tetranitrate; Hemodynamics; Humans; Isosorbide Dinitrate; Methods; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Physical Exertion; Substance-Related Disorders | 1976 |
Effects of isosorbide dinitrate and nitroglycerin on central circulatory dynamics in coronary artery disease.
Topics: Administration, Oral; Blood Pressure; Cardiac Output; Cardiac Volume; Coronary Disease; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Nitroglycerin | 1976 |
Combination vasodilator therapy for severe chronic congestive heart failure.
Topics: Chronic Disease; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Hydralazine; Isosorbide Dinitrate; Male; Middle Aged; Minoxidil; Nitroglycerin; Nitroprusside; Vasodilator Agents | 1976 |
[Influence of nitrates on regional myocardial blood flow and left ventricular wall motion].
Topics: Coronary Circulation; Coronary Disease; Diagnosis, Computer-Assisted; Heart Ventricles; Humans; Isosorbide Dinitrate; Myocardial Contraction; Nitrates; Nitroglycerin; Regional Blood Flow; Vascular Resistance; Xenon Radioisotopes | 1976 |
A kinetodardiographic approach to the evaluation of antianginal drugs.
Topics: Adult; Aged; Angina Pectoris; Coronary Circulation; Hemodynamics; Humans; Isosorbide Dinitrate; Kinetocardiography; Middle Aged; Nitroglycerin; Time Factors; Vascular Resistance; Vasodilator Agents | 1976 |
The significance of some noninvasive methods in the objective evaluation of treatment of patients with coronary artery disease.
Topics: Adult; Aged; Angina Pectoris; Ballistocardiography; Carotid Arteries; Coronary Disease; Drug Evaluation; Electrocardiography; Heart Conduction System; Heart Function Tests; Heart Ventricles; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Phonocardiography; Pulse | 1976 |
Treatment of congestive heart failure.
Topics: Benzothiadiazines; Bloodletting; Digitalis Glycosides; Diuretics; Heart; Heart Failure; Heart Function Tests; Hemodynamics; Humans; Isosorbide Dinitrate; Morphine; Myocardial Contraction; Nitroglycerin; Nitroprusside; Rest; Sodium Chloride Symporter Inhibitors; Stimulation, Chemical | 1976 |
[Precordial cartography following recent myocardial infarct. Attempted limitation of the infarct with nitrate derivatives].
Topics: Administration, Oral; Aspartate Aminotransferases; Electrocardiography; Humans; Infusions, Parenteral; Ischemia; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Prognosis | 1976 |
Prinzmetal's angina with coronary artery spasm. Angiographic, pharmacologic, metabolic and radionuclide perfusion studies.
Topics: Angina Pectoris; Angina Pectoris, Variant; Coronary Angiography; Coronary Circulation; Coronary Disease; Electrocardiography; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Pacemaker, Artificial; Radionuclide Imaging | 1976 |
[Behavior of coronary circulation and myocardial oxygen consumption in changes of peripheral vascular resistance].
Topics: Adult; Coronary Circulation; Heart; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Nitroprusside; Oxygen Consumption; Vascular Resistance | 1976 |
[Effect of i.v. nitroglycerin on the hemodynamics and size of infarct. Comparison with isosorbide dinitrate].
Topics: Administration, Oral; Hemodynamics; Humans; Injections, Intravenous; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin | 1976 |
Desensitization of nitrate-induced venodilation: reversal with oral N-acetylcysteine in humans.
Topics: Acetylcysteine; Adult; Blood Pressure Determination; Dose-Response Relationship, Drug; Drug Tolerance; Female; Hand; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Regional Blood Flow; Vasodilation | 1992 |
[The effect of nitroglycerin, nitrosorbide and nitroprusside on the intracellular content of Ca2+ ions in human lymphocytes].
Topics: Calcium; Concanavalin A; Cytosol; Dose-Response Relationship, Drug; Fluorescent Dyes; Fura-2; Humans; Isosorbide Dinitrate; Lymphocytes; Nitroglycerin; Nitroprusside; Time Factors | 1992 |
[Mechanism of cellular action of nitrate derivatives].
Topics: Cyclic GMP; Humans; Isosorbide Dinitrate; Muscle, Smooth, Vascular; Nitroglycerin; Protein Kinases; Vasodilation | 1992 |
Total prevention of the development of in vitro tolerance to organic nitrates. Experiments with antioxidants.
Topics: Animals; Antioxidants; Aorta, Thoracic; Drug Tolerance; Female; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Muscle Relaxation; Nitrates; Nitroglycerin; Parasympatholytics; Rabbits; Vasodilator Agents | 1992 |
Influence of nitrovasodilators on bovine pulmonary histamine release.
Topics: Animals; Cattle; Culture Techniques; Histamine; Histamine Release; Isosorbide Dinitrate; Lung; Nitroglycerin; Nitroprusside; Vasodilator Agents | 1992 |
[Solid phase extraction for GC detection analysis of isosorbide dinitrate and glycerol nitrate in human plasma].
Topics: Chromatography, Gas; Humans; Isosorbide Dinitrate; Nitroglycerin | 1992 |
[Nitrate derivatives and compliance of large arteries].
Topics: Blood Pressure; Compliance; Endothelium, Vascular; Humans; Isosorbide Dinitrate; Nitroglycerin | 1992 |
Nitrovasodilators as a new class of ocular hypotensive agents.
Topics: Administration, Topical; Animals; Aqueous Humor; Atrial Natriuretic Factor; Blood Pressure; Dose-Response Relationship, Drug; Intraocular Pressure; Isosorbide Dinitrate; Male; Molsidomine; Nitroglycerin; Nitroprusside; Rabbits; Vasodilator Agents | 1992 |
Nitrate tolerance. How to prevent it or minimize its effect.
Topics: Angina Pectoris; Drug Tolerance; Heart Failure; Humans; Isosorbide Dinitrate; Nitroglycerin | 1992 |
Nitrates.
Topics: Cardiovascular Diseases; Coronary Disease; Drug Interactions; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Patient Education as Topic | 1992 |
Massive ingestion of isosorbide-5-mononitrate and nitroglycerin: suicide attempt by an adolescent girl without previous heart disease.
Topics: Adolescent; Drug Overdose; Female; Humans; Isosorbide Dinitrate; Nitroglycerin; Suicide, Attempted; Tachycardia | 1992 |
Biotransformation of organic nitrates to nitric oxide by vascular smooth muscle and endothelial cells.
Topics: Animals; Aorta, Thoracic; Biotransformation; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Hot Temperature; Isosorbide Dinitrate; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Radioimmunoassay; Swine; Temperature | 1991 |
Molecular mechanisms of nitrovasodilator bioactivation.
Topics: Amyl Nitrite; Enzyme Activation; Guanylate Cyclase; Isosorbide Dinitrate; Methemoglobin; Molsidomine; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxyhemoglobins | 1991 |
Nitrate tolerance induced by nicorandil or nitroglycerin is associated with minimal loss of nicorandil vasodilator activity.
Topics: Animals; Arteries; Cattle; Coronary Vessels; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Nitric Oxide; Nitroglycerin; Vasodilator Agents | 1990 |
[Comparison of the clinical and hemodynamic effects of nitroglycerin, isosorbide dinitrate and isosorbide-5-mononitrate in acute myocardial infarction].
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Ventricular Function, Left | 1991 |
Nitrate tolerance: does tid isosorbide dinitrate mean dosing every eight hours?
Topics: Administration, Cutaneous; Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitroglycerin | 1991 |
An attempt to use artificial membranes to investigate cellular membrane permeation--application to nitroglycerin and isosorbide dinitrate.
Topics: Cell Membrane; Erythrocyte Membrane; Erythrocytes; Humans; In Vitro Techniques; Isosorbide Dinitrate; Membranes, Artificial; Nitroglycerin; Permeability | 1991 |
[Nitroglycerin absorption by infusion tubes].
Topics: Absorption; Diffusion; Drug Interactions; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Nitroglycerin; Polyvinyl Chloride; Time Factors | 1991 |
Mechanisms of nitrate-induced vasodilatation and tolerance.
Topics: Animals; Cattle; Coronary Vessels; Cysteine; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Vasodilation | 1990 |
[Therapeutic drug monitoring of nitrate and nitrite].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Biological Availability; Calcium Channel Blockers; Chromatography, Gas; Dosage Forms; Drug Therapy, Combination; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin | 1990 |
[Clinical significance of long-acting anti-anginal drugs in the treatment of cardiovascular diseases].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Delayed-Action Preparations; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitroglycerin | 1990 |
A symposium: Advances in nitrate therapy (Part 2). Montreux, Switzerland.
Topics: Heart Diseases; Humans; Isosorbide Dinitrate; Nitroglycerin | 1990 |
Reproducible uniform coronary vasomotor tone with nitrocompounds: prerequisite of quantitative coronary angiographic trials.
Topics: Angiography; Coronary Angiography; Coronary Disease; Female; Humans; Image Interpretation, Computer-Assisted; Isosorbide Dinitrate; Male; Middle Aged; Molsidomine; Nitro Compounds; Nitroglycerin; Radiographic Image Interpretation, Computer-Assisted; Reproducibility of Results; Vasodilation; Vasodilator Agents | 1990 |
Nitroglycerine tolerance.
Topics: Administration, Cutaneous; Administration, Sublingual; Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Exercise Test; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Nitroglycerin | 1990 |
The rapid onset of nitrate tolerance.
Topics: Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitroglycerin; Time Factors | 1990 |
Relaxation of bovine mesenteric arteries by glyceryl trinitrate and other nitro-compounds: evidence for partly different mechanisms of action.
Topics: Aminoquinolines; Animals; Cattle; Female; Isosorbide Dinitrate; Mesenteric Arteries; Mice; Muscle Relaxation; Nitroglycerin; Nitroprusside; Pertussis Toxin; Pregnancy; SRS-A; Virulence Factors, Bordetella | 1990 |
Assay of glyceryl trinitrate, isosorbide dinitrate, and their metabolites in plasma by large-bore capillary column gas-liquid chromatography.
Topics: Chromatography, Gas; Humans; Isosorbide Dinitrate; Nitroglycerin | 1990 |
Cytochrome P-450 mediated biotransformation of organic nitrates.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Chromatography, Gas; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; In Vitro Techniques; Isosorbide Dinitrate; Kinetics; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitroglycerin; Oxygen; Phenobarbital; Rats; Rats, Inbred Strains; Stereoisomerism | 1990 |
The effect of prenylamine and organic nitrates on the bioenergetics of bovine catecholamine storage vesicles.
Topics: Animals; Catecholamines; Cattle; Chromaffin Granules; Chromaffin System; Dopamine; Energy Metabolism; In Vitro Techniques; Isosorbide Dinitrate; Nitroglycerin; Prenylamine; Proton-Translocating ATPases | 1990 |
Comparison of the inhibitory effects of nicorandil, nitroglycerin and isosorbide dinitrate on vascular smooth muscle of rabbit aorta.
Topics: Animals; Aorta; Calcium; Cyclic GMP; In Vitro Techniques; Ion Channels; Isosorbide Dinitrate; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Rabbits | 1987 |
Nitrate tolerance: comparison of nicorandil, isosorbide dinitrate, and nitroglycerin in anesthetized dogs.
Topics: Anesthesia; Animals; Coronary Circulation; Dogs; Drug Tolerance; Female; Infusions, Intravenous; Injections, Intra-Arterial; Isosorbide Dinitrate; Male; Niacinamide; Nicorandil; Nitroglycerin; Vasodilator Agents | 1987 |
Cyclic GMP in nicorandil-induced vasodilatation and tolerance development.
Topics: Acetylcysteine; Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Vasodilation; Vasodilator Agents | 1987 |
Nitrate therapy for left ventricular failure complicating acute myocardial infarction: a haemodynamic comparison of intravenous, buccal, and transdermal delivery systems.
Topics: Administration, Buccal; Administration, Cutaneous; Administration, Oral; Adult; Aged; Blood Pressure; Cardiac Output; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin | 1989 |
Isosorbide dinitrate ameliorates myocardial ischemia after development of collateral function in a canine model.
Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Isosorbide Dinitrate; Nitroglycerin | 1989 |
Comparison of relaxation induced by glyceryl trinitrate, isosorbide dinitrate, and sodium nitroprusside in bovine airways.
Topics: Animals; Carbachol; Cattle; Dose-Response Relationship, Drug; Ferricyanides; In Vitro Techniques; Isoproterenol; Isosorbide Dinitrate; Lung; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Nitroglycerin; Nitroprusside; Trachea | 1989 |
Synthetic nitrovasodilators are effective, in vitro, in relaxing penile tissue from impotent men: the findings and their implications.
Topics: Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroglycerin; Norepinephrine; Penile Erection; Penis | 1989 |
Effectiveness of interval nitrate therapy in angina pectoris.
Topics: Administration, Cutaneous; Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1989 |
Follow-up the haemodynamic effect of nitroglycerin and determination of the optimal dose using the non-invasive and invasive methods in patients treated at the intensive care unit.
Topics: Aged; Aged, 80 and over; Coronary Disease; Female; Follow-Up Studies; Heart Failure; Hemodynamics; Humans; Intensive Care Units; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1989 |
[Ambulatory treatment of chronic cardiac insufficiency with prolonged administration of nitrates].
Topics: Administration, Oral; Cardiac Glycosides; Coronary Disease; Diuretics; Drug Evaluation; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Time Factors | 1989 |
Nitroglycerin and isosorbide dinitrate stimulation of glutathione disulfide efflux from perfused rat liver.
Topics: Animals; Bile; Biomarkers; Glutathione; Glutathione Disulfide; Isosorbide Dinitrate; L-Lactate Dehydrogenase; Liver; Male; Nitroglycerin; Oxidation-Reduction; Perfusion; Rats; Rats, Inbred Strains | 1989 |
Biotransformation of glyceryl trinitrate and isosorbide dinitrate in vascular smooth muscle made tolerant to organic nitrates.
Topics: Animals; Aorta, Thoracic; Biotransformation; Chromatography, Thin Layer; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Rabbits | 1989 |
Nitrate tolerance and its consequences for the clinician.
Topics: Angina Pectoris; Animals; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1989 |
[Transmembrane passage of trinitrine and isosorbide dinitrate. Study of natural membranes].
Topics: Cell Membrane Permeability; Diffusion; Erythrocyte Membrane; Humans; Isosorbide Dinitrate; Nitroglycerin; Time Factors | 1989 |
[The transmembrane diffusion of trinitrine and isosorbide dinitrate. Study of artificial membranes].
Topics: Cell Membrane Permeability; Diffusion; Erythrocytes; Humans; Isosorbide Dinitrate; Membranes, Artificial; Nitroglycerin | 1989 |
The effects of intravenous nitroglycerin and isosorbide dinitrate on hemodynamics and myocardial metabolism.
Topics: Adult; Aged; Atrial Function, Right; Blood Pressure; Coronary Artery Bypass; Coronary Circulation; Coronary Vessels; Halothane; Heart; Heart Rate; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Lactates; Male; Middle Aged; Myocardium; Nitroglycerin; Oxygen Consumption; Pulmonary Artery; Pulmonary Wedge Pressure; Vascular Resistance | 1989 |
Effect of pertussis toxin and the cGMP lowering agent LY83583 on the relaxation induced by nitrates in isolated bovine mesenteric artery. A comparison between glyceryl trinitrate, isosorbide dinitrate and isosorbide 5-mononitrate.
Topics: Aminoquinolines; Animals; Cattle; Cyclic GMP; Isosorbide Dinitrate; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Pertussis Toxin; Vascular Resistance; Virulence Factors, Bordetella | 1989 |
[Isolated human venous segments as a model for the study of problems of nitrate tolerance].
Topics: Acetylcysteine; Coronary Artery Bypass; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Isosorbide Dinitrate; Muscle, Smooth, Vascular; Nitroglycerin; Saphenous Vein; Vascular Resistance; Vasodilation | 1989 |
Nitroglycerin-induced tolerance affects multiple sites in the organic nitrate bioconversion cascade.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; Drug Tolerance; Endothelium, Vascular; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Nitric Oxide; Nitroglycerin; Nitroprusside; Parasympatholytics; Vasodilator Agents | 1989 |
[Drugs in secondary prevention of ischemic heart disease: achievements, problems and prospects].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Nadolol; Nifedipine; Nitrates; Nitroglycerin; Propranolol; Verapamil | 1989 |
Effects of atrial natriuretic polypeptide and organic nitrates on levels of relaxation and cyclic nucleotide of canine coronary artery with and without endothelial injury.
Topics: Animals; Atrial Natriuretic Factor; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dogs; Endothelium, Vascular; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilation | 1988 |
[New approaches to the study of the mechanism of action of nitrates].
Topics: Blood Platelets; Calcium; Calcium Channel Blockers; Calcium Channels; Cardiomegaly; Ferricyanides; Heart Failure; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitroglycerin; Nitroprusside; Receptors, Cell Surface | 1988 |
Clinical pharmacology of vasodilator drugs.
Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Coronary Disease; Humans; Hydralazine; Hypertension; Isosorbide Dinitrate; Kinetics; Liver; Muscle Contraction; Muscle, Smooth, Vascular; Nitroglycerin; Prazosin; Vasodilator Agents; Verapamil | 1985 |
Mode of action of nitrates with regard to vasodilatation and tolerance.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Nitrates; Nitroglycerin; Vasodilation | 1986 |
Mechanism of vasodilation by nitrates: role of cyclic GMP.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Nitrates; Nitroglycerin; Vasodilator Agents | 1987 |
Use of nitrates in unstable angina pectoris.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Drug Therapy, Combination; Fluorobenzenes; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Nitroglycerin; Propanolamines | 1987 |
Nitrates do not affect prostacyclin formation by rat arteries: this is unrelated to increased vascular prostacyclin formation with age.
Topics: 6-Ketoprostaglandin F1 alpha; Aging; Animals; Arteries; Epoprostenol; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Rats; Rats, Inbred Strains | 1987 |
Medications in angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Humans; Isosorbide Dinitrate; Nitroglycerin | 1988 |
Guanylate cyclase activation by organic nitrates is not mediated via nitrite.
Topics: Enzyme Activation; Guanylate Cyclase; Isosorbide Dinitrate; Kinetics; Niacinamide; Nicorandil; Nitrates; Nitrites; Nitroglycerin; Sulfhydryl Compounds; Vasodilator Agents | 1988 |
Cardiovascular effects of isosorbide dinitrate infused intravenously into anaesthetized dogs.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Female; Hemodynamics; Infusions, Intravenous; Isosorbide Dinitrate; Male; Niacinamide; Nicorandil; Nitroglycerin; Stroke Volume | 1986 |
[Influence of antianginal drugs on Lypressin induced T-wave enhancement in the electrocardiogram of the rat].
Topics: Administration, Oral; Angina Pectoris; Animals; Coronary Vasospasm; Electrocardiography; Hypoxia; Isosorbide Dinitrate; Lypressin; Male; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Comparative vasorelaxing profiles of nicorandil, isosorbide dinitrate and nitroglycerin in isolated coronary arteries of the dog.
Topics: Acetylcysteine; Animals; Coronary Vessels; Dinoprost; Dogs; Endothelium; Female; In Vitro Techniques; Isosorbide Dinitrate; Male; Methylene Blue; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Chloride; Prostaglandins F; Vasodilator Agents | 1987 |
Mechanisms of nitrate-induced vasodilatation and tolerance on a biochemical base.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Pressure; Cattle; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Isosorbide Dinitrate; Methylene Blue; Nitrates; Nitroglycerin; Nitroprusside; Vasodilation | 1985 |
Hemodynamic attenuation and the nitrate-free interval: alternative dosing strategies for transdermal nitroglycerin.
Topics: Acetylcysteine; Administration, Oral; Administration, Topical; Angina Pectoris; Angina, Unstable; Animals; Blood Vessels; Cheek; Cyclic GMP; Drug Administration Schedule; Drug Tolerance; Electrocardiography; Endothelium; Exercise Test; Hemodynamics; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Nitroglycerin; Prostaglandins; Vascular Resistance | 1985 |
Hemodynamic factors limiting the response to transdermal nitroglycerin in severe chronic congestive heart failure.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Drug Tolerance; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Substance Withdrawal Syndrome; Time Factors; Vascular Resistance | 1986 |
Nitro compounds (isosorbide dinitrate, 5-isosorbide mononitrate and glyceryl trinitrate) on the femoral vein and femoral artery.
Topics: Animals; Dose-Response Relationship, Drug; Femoral Artery; Femoral Vein; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Rabbits | 1986 |
Clinical relevance of nitrate hemodynamic attenuation.
Topics: Administration, Topical; Angina Pectoris; Coronary Disease; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Receptors, Drug; Vasodilation | 1986 |
Sorption of four drugs to polyvinyl chloride and polybutadiene intravenous administration sets.
Topics: Adsorption; Butadienes; Chlormethiazole; Diazepam; Elastomers; Infusions, Parenteral; Isosorbide Dinitrate; Nitroglycerin; Pharmaceutical Preparations; Polymers; Polyvinyl Chloride; Polyvinyls | 1986 |
[Calcium-blocking action of nitro compounds on human thrombocytes].
Topics: Blood Platelets; Calcium Channel Blockers; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitroglycerin; Nitroprusside; Vasodilator Agents | 1986 |
Thin-layer chromatography of isosorbide dinitrate, nitroglycerin and their degradation products.
Topics: Chromatography, Thin Layer; Indicators and Reagents; Isosorbide Dinitrate; Nitroglycerin | 1986 |
[Dinitrosorbilong--a new Soviet anti-angina preparation. Its comparative pharmacodynamic, pharmacokinetic and clinical study].
Topics: Angina Pectoris; Coronary Disease; Delayed-Action Preparations; Drug Evaluation; Exercise Test; Humans; Isosorbide Dinitrate; Kinetics; Nitroglycerin; Physical Exertion; Tablets | 1986 |
Effects of nitro compounds, isosorbide dinitrate, 5-isosorbide mononitrate and glyceryl trinitrate on Ca-uptake into Ca-stores and Ca-release from Ca-stores in rabbit isolated femoral veins and femoral arteries.
Topics: Animals; Blood Vessels; Calcium; Femoral Artery; Femoral Vein; In Vitro Techniques; Isosorbide Dinitrate; Male; Nitro Compounds; Nitroglycerin; Rabbits; Vasodilator Agents | 1987 |
[Comparative evaluation of the efficacy of nitrosorbide and nitroglycerin in acute myocardial infarct patients].
Topics: Acute Disease; Angina Pectoris; Arrhythmias, Cardiac; Dyspnea, Paroxysmal; Electrocardiography; Female; Heart Failure; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Time Factors | 1987 |
[Corrective effect of nitrates and calcium antagonists on hemodynamics and ventilation in chronic bronchitis patients with a syndrome of pulmonary hypertension].
Topics: Bronchitis; Calcium Channel Blockers; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension, Pulmonary; Isosorbide Dinitrate; Nifedipine; Nitrates; Nitroglycerin; Pulmonary Heart Disease; Respiration; Vasodilator Agents; Verapamil | 1987 |
Application of a combination of sublingually administered vasodilating drugs for rapid action on pulmonary hypertension in patients with cardiac asthma and with pulmonary oedema.
Topics: Administration, Oral; Adult; Aged; Drug Therapy, Combination; Dyspnea, Paroxysmal; Female; Heart Failure; Humans; Hypertension, Pulmonary; Isosorbide Dinitrate; Male; Middle Aged; Molsidomine; Nitroglycerin; Pulmonary Edema; Vasodilator Agents | 1987 |
Historical aspects of nitrate therapy.
Topics: Cardiovascular Diseases; History, 19th Century; History, 20th Century; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentanols | 1987 |
Determination of nitrates in plasma.
Topics: Biotransformation; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1987 |
[Infusion treatment with nitrites of patients with acute myocardial infarct and unstable angina pectoris].
Topics: Angina Pectoris; Angina, Unstable; Blood Pressure; Drug Evaluation; Heart Rate; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Time Factors | 1987 |
Role of nitrates in congestive heart failure.
Topics: Dosage Forms; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Hydralazine; Isosorbide Dinitrate; Nitroglycerin | 1987 |
Nitrate tolerance.
Topics: Dosage Forms; Drug Tolerance; Hemodynamics; Humans; Isosorbide Dinitrate; Nitroglycerin | 1987 |
[Hemodynamic effect of unloading therapy in acute myocardial infarction with congestive heart failure].
Topics: Age Factors; Aged; Female; Ferricyanides; Heart Failure; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Nitroprusside | 1987 |
Comparison of different pharmacological interventions on enzymatic parameters during acute myocardial infarction.
Topics: Adult; Aged; Clinical Enzyme Tests; Creatine Kinase; Dipyridamole; Female; Heart; Heparin; Humans; Isoenzymes; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Nifedipine; Nitroglycerin; Streptokinase; Verapamil | 1987 |
A symposium: Advances in clinical practice of nitrate therapy. March 31, 1987, Montreux, Switzerland. Proceedings.
Topics: Heart Diseases; Humans; Isosorbide Dinitrate; Nitroglycerin | 1988 |
Comparative evaluation of isosorbide-5-mononitrate and nitroglycerin in chronic congestive heart failure.
Topics: Aged; Blood Pressure; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Nitroglycerin | 1988 |
Reduction of nitroglycerin and isosorbide dinitrate by hemodialysis in refractory angina pectoris after acute myocardial infarction.
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Renal Dialysis | 1988 |
[Comparison of the effects of depot peroral and transdermal administration of nitrate preparations].
Topics: Administration, Cutaneous; Administration, Oral; Adult; Angina Pectoris; Delayed-Action Preparations; Electrocardiography; Exercise Test; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1988 |
Patterns of isosorbide dinitrate and glyceryl trinitrate metabolites formed by selected segments of the rabbit gastrointestinal tract.
Topics: Animals; Biotransformation; Chromatography, Gas; Digestive System; In Vitro Techniques; Intestinal Mucosa; Isosorbide Dinitrate; Male; Nitroglycerin; Rabbits | 1988 |
[Nitrate tolerance: non-intravenous use].
Topics: Administration, Oral; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitroglycerin | 1988 |
Slow-release isosorbide-5-mononitrate--a new once daily therapeutic modality for angina pectoris.
Topics: Administration, Oral; Adult; Angina Pectoris; Delayed-Action Preparations; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Physical Exertion | 1988 |
Stimulation of coronary vascular PGI2 by organic nitrates.
Topics: Animals; Cattle; Coronary Vessels; Epoprostenol; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Platelet Aggregation; Stereoisomerism; Structure-Activity Relationship; Sugar Alcohols; Thromboxane A2; Vasodilator Agents | 1988 |
When does nitrate tolerance develop? What dosages and which intervals are necessary to ensure maintained effectiveness?
Topics: Administration, Cutaneous; Administration, Oral; Angina Pectoris; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Electrocardiography; Exercise Test; Humans; Isosorbide Dinitrate; Nitroglycerin; Random Allocation | 1988 |
Nitrates: the problem of tolerance.
Topics: Angina Pectoris; Drug Tolerance; Heart Failure; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1988 |
[Nitrate tolerance].
Topics: Administration, Oral; Angina Pectoris; Dosage Forms; Drug Resistance; Hemodynamics; Humans; Injections, Intravenous; Isosorbide Dinitrate; Nitroglycerin | 1988 |
Abrupt withdrawal of isosorbide-5-mononitrate in Durules (Imdur) after long term treatment in patients with stable angina pectoris.
Topics: Acute Disease; Aged; Angina Pectoris; Delayed-Action Preparations; Drug Tolerance; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Substance Withdrawal Syndrome | 1988 |
[Arterial and venous dilation using nitroglycerin and isosorbide dinitrate during cardiopulmonary bypass].
Topics: Adult; Aged; Arteries; Cardiopulmonary Bypass; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Vasodilation; Veins | 1988 |
Nitric oxide-induced vasodilation of organic nitrate-tolerant rabbit aorta.
Topics: Animals; Aorta, Thoracic; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Rabbits; Vasodilation | 1988 |
Clinical experience of percutaneous transluminal coronary angioplasty--technique and results.
Topics: Adult; Aged; Angina Pectoris; Angioplasty, Balloon; Aspirin; Coronary Angiography; Coronary Disease; Dipyridamole; Female; Follow-Up Studies; Heparin; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nifedipine; Nitroglycerin; Recurrence | 1985 |
Nitrates and endothelial prostacyclin production: studies in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Blood Vessels; Cells, Cultured; Endothelium; Epoprostenol; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Thromboxane B2; Vasodilator Agents | 1985 |
[Possibility of developing tolerance to the anti-anginal effect of isosorbide dinitrate and verapamil].
Topics: Adult; Angina Pectoris; Drug Tolerance; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Verapamil | 1985 |
[Effect of nitrates and obsidan on myocardial infarction].
Topics: Adult; Aged; Drug Synergism; Drug Therapy, Combination; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Propranolol | 1985 |
Isosorbide dinitrate and glyceryl trinitrate: demonstration of cross tolerance in the capacitance vessels.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Blood Volume Determination; Drug Tolerance; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Regional Blood Flow; Time Factors; Vascular Resistance; Veins | 1985 |
The influence of captopril, the nitrates and propranolol on apparent liver blood flow.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Interactions; Half-Life; Heart Rate; Humans; Indocyanine Green; Isosorbide Dinitrate; Liver Circulation; Male; Nitroglycerin; Posture; Proline; Propranolol; Renin | 1985 |
[Pharmacokinetics and metabolism of organic nitrates].
Topics: Angina Pectoris; Biological Availability; Biotransformation; Drug Tolerance; Humans; Isosorbide Dinitrate; Kinetics; Metabolic Clearance Rate; Nitroglycerin | 1985 |
[Significance of nitrates in acute therapy of heart failure with and without lung edema].
Topics: Cardiac Output, Low; Cardiomyopathy, Dilated; Dobutamine; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pulmonary Edema; Regional Blood Flow; Shock, Cardiogenic | 1985 |
[Characteristics of patients with ischemic heart disease under dispensary observation in a regional polyclinic and the evaluation of anti-angina therapy conducted under dispensary conditions].
Topics: Adult; Ambulatory Care; Amiodarone; Angina Pectoris; Coronary Disease; Drug Therapy, Combination; Follow-Up Studies; Humans; Isosorbide Dinitrate; Male; Nifedipine; Nitroglycerin; Propranolol; Time Factors; Vasodilator Agents; Verapamil | 1985 |
[Pharmacodynamic effects of VUFB's isosorbide dinitrate and Spofa's nitroglycerin].
Topics: Coronary Disease; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1985 |
Role of hemoglobin in the differential biotransformation of glyceryl trinitrate and isosorbide dinitrate by human erythrocytes.
Topics: Adult; Biotransformation; Carbon Monoxide; Erythrocytes; Ferricyanides; Hemoglobins; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Nitroglycerin; Oxidation-Reduction | 1985 |
High-dose isosorbide dinitrate in management of angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Drug Administration Schedule; Exercise Test; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Patient Compliance; Pulse; Time Factors | 1985 |
[Pharmacodynamics of a nitroglycerin ointment in patients with stenocardia of effort].
Topics: Administration, Topical; Adult; Angina Pectoris; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Evaluation; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Ointments; Time Factors | 1985 |
[Comparative evaluation of the effectiveness of various peripheral vasodilators in the treatment of cardiac insufficiency].
Topics: Administration, Oral; Adolescent; Adult; Captopril; Chronic Disease; Female; Heart Failure; Hemodynamics; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Prazosin; Vasodilator Agents | 1985 |
[Comparison of the hypotensive effects of nitroglycerin (Nitrox-Spray) and isosorbide dinitrate (IsoMack-Spray) in rats].
Topics: Animals; Blood Pressure; Female; Hypotension; Isosorbide Dinitrate; Male; Nitroglycerin; Rats; Rats, Inbred Strains | 1985 |
[Nitrates in the complex treatment of circulatory failure].
Topics: Adult; Aged; Cardiac Glycosides; Drug Therapy, Combination; Female; Heart Failure; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1985 |
[High performance liquid chromatographic assay and determination of the even distribution of active ingredients in nitroglycerin and isosorbide dinitrate tablets].
Topics: Chromatography, High Pressure Liquid; Isosorbide Dinitrate; Nitroglycerin; Tablets | 1985 |
Nitrate tolerance.
Topics: Administration, Topical; Angina Pectoris; Blood Pressure; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Time Factors; Vasodilator Agents | 1985 |
[Relation between therapeutic efficacy of antianginal preparations in patients with ischemic heart disease and their effect on the rheologic properties of blood].
Topics: Adult; Amiodarone; Benzofurans; Blood Coagulation; Blood Viscosity; Coronary Disease; Erythrocyte Aggregation; Humans; Isosorbide Dinitrate; Male; Middle Aged; Molsidomine; Nitroglycerin; Oxadiazoles; Platelet Adhesiveness; Platelet Aggregation; Propranolol; Sydnones; Vasodilator Agents | 1985 |
[Nitrates and tolerance].
Topics: Animals; Cross Reactions; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Tachyphylaxis | 1985 |
[Nitrates in ischemic heart disease: the dependence of the effect on the route of administration and dosage of the preparation].
Topics: Administration, Oral; Coronary Disease; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Evaluation; Electrocardiography; Humans; Injections, Intravenous; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Ointments; Tablets; Time Factors | 1985 |
Isosorbide-5-mononitrate--effective monotherapy in chronic stable angina.
Topics: Administration, Oral; Aged; Angina Pectoris; Chronic Disease; Coronary Disease; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Physical Exertion | 1985 |
Angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Diagnosis, Differential; Heart; Humans; Isosorbide Dinitrate; Nitroglycerin | 1972 |
Guidelines in the drug treatment of angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Heart; Humans; Isosorbide Dinitrate; Nitroglycerin; Oxygen Consumption | 1974 |
A practical approach to the management of angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arm; Arrhythmias, Cardiac; Digitalis Glycosides; Diuretics; Exercise Therapy; Heart Failure; Humans; Isosorbide Dinitrate; Meperidine; Nitroglycerin; Physical Exertion; Stress, Psychological | 1974 |
Intractable angina pectoris.
Topics: Angina Pectoris; Antithyroid Agents; Coronary Vessels; Electric Stimulation; Humans; Hypnotics and Sedatives; Isosorbide Dinitrate; Nitroglycerin; Propranolol; Tranquilizing Agents | 1970 |
GLC determination of nitroglycerin and isosorbide dinitrate in human plasma.
Topics: Chromatography, Gas; Furans; Humans; Isosorbide Dinitrate; Methods; Nitrates; Nitroglycerin; Time Factors; Vasodilator Agents | 1973 |
Drugs for angina pectoris.
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Nitroglycerin; Placebos; Propranolol; Statistics as Topic; Verapamil | 1973 |
Bioavailability studies of nitrates in the dog.
Topics: Administration, Oral; Animals; Biopharmaceutics; Blood Pressure; Cardiovascular System; Delayed-Action Preparations; Dogs; Dose-Response Relationship, Radiation; Heart; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Oxygen Consumption; Pentaerythritol Tetranitrate; Pulse; Vasodilator Agents | 1973 |
Variant angina pectoris caused by coronary artery spasm.
Topics: Angina Pectoris; Arteries; Cardiac Catheterization; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Coronary Vessel Anomalies; Electrocardiography; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Postoperative Complications; Saphenous Vein; Spasm; Tachycardia; Transplantation, Autologous | 1974 |
What constitutes adequate medical therapy for the patient with angina pectoris?
Topics: Aged; Angina Pectoris; Arteriosclerosis; Delayed-Action Preparations; Drug Synergism; Drug Therapy, Combination; Electrocardiography; Erythrityl Tetranitrate; Exercise Test; Heart Rate; Hospitalization; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Propranolol | 1974 |
[Therapy of angina pectoris. II. Evaluation of antianginous drugs. Nitrites and nitrates].
Topics: Amyl Nitrite; Angina Pectoris; Drug Evaluation; Humans; Isosorbide Dinitrate; Mannitol; Nitrates; Nitrites; Nitroglycerin | 1974 |
Right coronary arterial spasm causing Prinzmetal's variant angina.
Topics: Adult; Angina Pectoris; Arteriosclerosis; Coronary Angiography; Coronary Disease; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Spasm | 1974 |
Letter: Treatment of angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Evaluation; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitroglycerin; Ointments; Time Factors | 1974 |
Letter: Treatment of angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Evaluation; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitroglycerin; Ointments; Time Factors | 1974 |
[The effect of vasodilators on the intraocular pressure (author's transl)].
Topics: Administration, Intranasal; Administration, Oral; Benzyl Compounds; Blood Pressure; Cycloheptanes; Dimethylamines; Electroretinography; Fluorescein Angiography; Fundus Oculi; Glaucoma; Humans; Injections, Intravenous; Intraocular Pressure; Isosorbide Dinitrate; Nitroglycerin; Tablets; Time Factors; Tonometry, Ocular; Vasodilator Agents | 1974 |
[Proceedings: Oral nitroglycerin preparations in the therapy of left heart failure in acute myocardial infarct].
Topics: Administration, Oral; Heart Failure; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin | 1974 |
Atherosclerotic coronary artery aneurysm. Report of five cases and review of literature.
Topics: Adult; Aneurysm; Blood Vessel Prosthesis; Cardiac Catheterization; Coronary Artery Bypass; Coronary Disease; Female; Follow-Up Studies; Humans; Infant; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Revascularization; Nitroglycerin; Propranolol; Radiography; Saphenous Vein; Transplantation, Autologous; Warfarin | 1974 |
Factors influencing the rehabilitation of the patient with ischaemic heart disease.
Topics: Adult; Age Factors; Angina Pectoris; Anticoagulants; Attitude; Australia; Coronary Disease; Culture; Diet Therapy; Diet, Sodium-Restricted; Dietary Fats; Drug Synergism; Exercise Therapy; Family; Family Practice; Humans; Interpersonal Relations; Isosorbide Dinitrate; Mental Disorders; Middle Aged; Motivation; Nitroglycerin; Personality Disorders; Physician-Patient Relations; Propranolol; Psychotherapy, Group; Socioeconomic Factors; Sympatholytics; Transients and Migrants; Unemployment; Vasodilator Agents; Workers' Compensation | 1969 |
The "natural" history of severe angina pectoris with intensive medical therapy alone: a five year prospective study of 133 patients.
Topics: Adult; Aged; Aging; Angina Pectoris; Atrial Fibrillation; Cardiomegaly; Cerebrovascular Disorders; Diabetes Complications; Electrocardiography; Female; Heart Auscultation; Heart Failure; Humans; Hypertension; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Prognosis; Propranolol; Prospective Studies | 1974 |
Proceedings: The influence of coronary dilators on the ischemic tolerance of the normothermic heart of the cat.
Topics: Animals; Blood Pressure; Cats; Coronary Vessels; Heart; Heart Arrest; Isosorbide Dinitrate; Nitroglycerin; Papaverine; Perfusion; Time Factors; Vasodilator Agents | 1974 |
Effect of certain drugs on perfused human placenta. 8. Angiotensin-II antagonists.
Topics: Acetates; Angiotensin II; Atropine; Blood Pressure Determination; Cobalt; Cocaine; Cyproheptadine; Dibenzylchlorethamine; Dipyridamole; Ethanol; Female; Furans; Glycols; Humans; Hydralazine; In Vitro Techniques; Isosorbide Dinitrate; Muscles; Nitrates; Nitrites; Nitroglycerin; Papaverine; Perfusion; Phentolamine; Placenta; Pregnancy; Sodium; Sympatholytics; Tartrates; Tolazoline | 1968 |
Pharmacologic and biochemical evaluation of organic nitrates: attempted correlation of activities.
Topics: Animals; Chemistry, Organic; Dogs; Electron Transport; Erythrityl Tetranitrate; Evaluation Studies as Topic; Heart; In Vitro Techniques; Isosorbide Dinitrate; Mannitol; Mitochondria, Muscle; Myocardium; NAD; Nitrates; Nitroglycerin; Organic Chemistry Phenomena; Oxidative Phosphorylation; Oxidoreductases; Pentaerythritol Tetranitrate; Rats; Vasodilator Agents | 1971 |
Variant angina associated with angiographically demonstrated coronary artery spasm and REM sleep.
Topics: Adult; Affective Symptoms; Angina Pectoris; Angiocardiography; Coronary Disease; Electrocardiography; Electroencephalography; Female; Humans; Isosorbide Dinitrate; Nitroglycerin; Propranolol; Sleep, REM; Spasm | 1973 |
Atrial pacing.
Topics: Angina Pectoris; Atrial Fibrillation; Electrocardiography; Evaluation Studies as Topic; Humans; Isosorbide Dinitrate; Nitroglycerin; Pacemaker, Artificial | 1972 |
Systemic and coronary vascular effects of the 2- and the 5-mononitrate esters of isosorbide.
Topics: Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; Electrocardiography; Furans; Heart Rate; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Perfusion; Pulse; Vascular Resistance | 1972 |
Organic nitrates: relationship between biotransformation and rational angina pectoris therapy.
Topics: Angina Pectoris; Animals; Biotransformation; Carbon Isotopes; Furans; Humans; Isosorbide Dinitrate; Liver; Mannitol; Nitrates; Nitroglycerin; Oxidoreductases; Rats; Vasodilator Agents | 1972 |
Clearance and metabolism of organic nitrates.
Topics: Adenosine Triphosphate; Animals; Blood; Carbon Isotopes; Erythrityl Tetranitrate; Glutathione; In Vitro Techniques; Isosorbide Dinitrate; Kinetics; Liver; Mannitol; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Rats | 1972 |
Medical treatment of angina pectoris. 3. Pharmacology of sublingual nitrites as antianginal drugs.
Topics: Angina Pectoris; Blood Flow Velocity; Blood Vessels; Dipyridamole; Furans; Heart; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardium; Nitrates; Nitrites; Nitroglycerin; Oxygen Consumption; Vasodilator Agents | 1972 |
The patient with angina. Medical management plus sympathetic, continuous care.
Topics: Angina Pectoris; Arterial Occlusive Diseases; Carotid Body; Coronary Vessels; Drug Synergism; Electric Stimulation; Exercise Therapy; Heart Rate; Humans; Isosorbide Dinitrate; Myocardium; Nitroglycerin; Oxygen Consumption; Propranolol; Saphenous Vein; Transplantation, Autologous | 1973 |
Variant angina of Prinzmetal with normal coronary arteriograms. A variant of the variant.
Topics: Adult; Angina Pectoris; Arrhythmias, Cardiac; Cardiac Catheterization; Cineangiography; Coronary Angiography; Electrocardiography; Exercise Test; Heart Auscultation; Hemoglobins; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Oxygen; Pacemaker, Artificial; Phonocardiography | 1973 |
The surgical management of coronary disease.
Topics: Angiography; Coronary Disease; Humans; Isosorbide Dinitrate; Nitroglycerin; Postoperative Complications | 1966 |
Medical perspectives of coronary artery disease.
Topics: Angina Pectoris; Anticoagulants; Coronary Disease; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Pentaerythritol Tetranitrate | 1967 |
The anti-anginal effect of rapidly acting nitrates in subjects with ergot-induced angina.
Topics: Adult; Angina Pectoris; Electrocardiography; Ergot Alkaloids; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrites; Nitroglycerin | 1967 |
A correlation between the inhibition of monoamine oxidase activity and the relief of angina pain by organic nitrates.
Topics: Angina Pectoris; Animals; Carbon Isotopes; Erythrityl Tetranitrate; Furans; Humans; Isosorbide Dinitrate; Mannitol; Mitochondria, Muscle; Monoamine Oxidase Inhibitors; Myocardium; Nitrates; Nitroglycerin; Vasodilator Agents | 1968 |
Cardiopulmonary effects of glyceryl trinitrate and isosorbide dinitrate.
Topics: Animals; Blood; Coronary Vessels; Dogs; Furans; Heart; Heart Ventricles; Hemodynamics; Injections, Intravenous; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pulmonary Circulation; Regional Blood Flow; Vasodilator Agents | 1968 |
[Therapy of primary pulmonary hypertension].
Topics: Acetylcholine; Amino Alcohols; Carbachol; Child; Diazepam; Diazoxide; Female; Humans; Hypertension, Pulmonary; Isoproterenol; Isosorbide Dinitrate; Neostigmine; Nitroglycerin; Pentaerythritol Tetranitrate; Rest; Theophylline; Tolazoline; Verapamil | 1970 |
The use of isosorbide dinitrate in status anginosus.
Topics: Adult; Age Factors; Aged; Angina Pectoris; Electrocardiography; Female; Furans; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin | 1970 |
[Conservative therapy of angina pectoris].
Topics: Acute Disease; Amyl Nitrite; Angina Pectoris; Anticoagulants; Coronary Disease; Digitalis Glycosides; Furans; Heart Failure; Humans; Hypotension, Orthostatic; Isosorbide Dinitrate; Morphine; Myocardial Infarction; Nitrates; Nitrites; Nitroglycerin; Pentaerythritol Tetranitrate; Propranolol; Rest; Sympatholytics; Syncope; Vascular Headaches | 1970 |
An internist looks at myocardial revascularization.
Topics: Angina Pectoris; Angiography; Chlordiazepoxide; Collateral Circulation; Coronary Disease; Diazepam; Electrocardiography; Female; Heart Aneurysm; Heart Diseases; Heart Valve Diseases; Humans; Hypertension; Isosorbide Dinitrate; Male; Myocardial Infarction; Nitroglycerin; Propranolol | 1971 |
'Progress' in the treatment and prevention of coronary heart disease.
Topics: Adolescent; Adult; Angina Pectoris; Anti-Arrhythmia Agents; Anticoagulants; Arrhythmias, Cardiac; Arteriosclerosis; Child; Coronary Disease; Diet Therapy; Dietary Fats; Drug Synergism; Exercise Therapy; Humans; Isosorbide Dinitrate; Long-Term Care; Middle Aged; Myocardial Infarction; Nitroglycerin; Propranolol; Smoking Prevention; Stress, Psychological | 1971 |
A ten-year reevaluation. Nitroglycerin and isosorbide dinitrate in coronary insufficiency.
Topics: Aged; Angina Pectoris; Female; Furans; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin | 1971 |
Hypotension during coronary arteriography.
Topics: Angiocardiography; Drug Synergism; Humans; Hypotension; Isosorbide Dinitrate; Nitroglycerin | 1971 |
[Importance of a comprehensive evaluation of the size of cardiac muscle necrosis for the prognosis and treatment of acute myocardial infarct patients].
Topics: Aged; Creatine Kinase; Diphosphates; Drug Therapy, Combination; Electrocardiography; Female; Heart; Humans; Isoenzymes; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Myocardium; Myoglobin; Necrosis; Nitroglycerin; Prognosis; Radionuclide Imaging; Technetium; Technetium Tc 99m Pyrophosphate; Time Factors | 1984 |
[Drug therapy of coronary disease. What is assured and what is possible in general practice?].
Topics: Adrenergic beta-Antagonists; Calcium; Coronary Disease; Digitalis Glycosides; Humans; Isosorbide Dinitrate; Nitroglycerin | 1980 |
Hypotensive effects and biotransformation of nicorandil, a new antianginal agent, administered to rats by different routes: comparison with nitroglycerin and isosorbide dinitrate.
Topics: Animals; Antihypertensive Agents; Biotransformation; Blood Pressure; Dogs; Guinea Pigs; In Vitro Techniques; Isosorbide Dinitrate; Liver; Macaca mulatta; Male; Niacinamide; Nicorandil; Nitroglycerin; Rats; Rats, Inbred Strains; Swine; Vasodilator Agents | 1984 |
Prevention of cardiac hypertrophy by long-term treatment with isosorbide dinitrate and prazosin but not by minoxidil in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cardiomegaly; Female; Hypertension; Isosorbide Dinitrate; Male; Minoxidil; Muscle Relaxation; Nitroglycerin; Prazosin; Pyrimidines; Quinazolines; Rats; Rats, Inbred Strains | 1984 |
Effects of vasodilators on the systemic capacitance vessels, a study with the measurement of the mean circulatory pressure in dogs.
Topics: Animals; Blood Pressure; Blood Vessels; Blood Volume; Cardiac Output; Diltiazem; Dogs; Heart Rate; Isosorbide Dinitrate; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Prazosin; Sydnones; Trapidil; Vascular Resistance; Vasodilator Agents; Venous Pressure; Verapamil | 1984 |
Nitrate therapy in a patient with papillary dysfunction.
Topics: Ampulla of Vater; Common Bile Duct Diseases; Female; Humans; Isosorbide Dinitrate; Middle Aged; Nitrates; Nitroglycerin; Sphincter of Oddi | 1983 |
[Combined treatment of coronary heart disease with diltiazem and isosorbide dinitrate].
Topics: Aged; Angina Pectoris; Benzazepines; Blood Pressure; Coronary Disease; Diltiazem; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1983 |
Intravenous nitroglycerin for the treatment of angina at rest unresponsive to standard nitrate therapy.
Topics: Adult; Aged; Angina Pectoris, Variant; Coronary Vasospasm; Female; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1983 |
Determination of vasodilators and their metabolites in plasma by liquid chromatography with a nitrosyl-specific detector.
Topics: Chromatography, High Pressure Liquid; Humans; Isosorbide Dinitrate; Nitroglycerin; Pentaerythritol Tetranitrate | 1983 |
Angina in thyrotoxicosis. Thyroid-related coronary artery spasm.
Topics: Angina Pectoris; Angiography; Ergonovine; Humans; Hyperthyroidism; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Propranolol; Thyroxine | 1983 |
Validation of high-performance liquid chromatographic methods for analysis of sustained-release preparations containing nitroglycerin, isosorbide dinitrate, or pentaerythritol tetranitrate.
Topics: Acetonitriles; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dimethyl Sulfoxide; Isosorbide Dinitrate; Nitroglycerin; Pentaerythritol Tetranitrate | 1983 |
Calcium antagonists, nitrates, and new antianginal drugs.
Topics: Angina Pectoris; Calcium Channel Blockers; Humans; Hypertension; Isosorbide Dinitrate; Lidoflazine; Nifedipine; Nitrates; Nitroglycerin; Perhexiline; Prenylamine; Tachycardia; Verapamil | 1983 |
The effects of glyceryl trinitrate, isosorbide dinitrate and sodium nitroprusside on haemodynamics, coronary blood flow and myocardial oxygen consumption - an experimental study.
Topics: Animals; Coronary Circulation; Dogs; Ferricyanides; Hemodynamics; Isosorbide Dinitrate; Myocardium; Nitroglycerin; Nitroprusside; Oxygen Consumption | 1983 |
Nitrate tolerance: influence of isosorbide dinitrate on the hemodynamic and antianginal effects of nitroglycerin.
Topics: Acute Disease; Administration, Oral; Angina Pectoris; Blood Pressure; Drug Interactions; Drug Tolerance; Exercise Test; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Placebos; Time Factors | 1983 |
Pharmacokinetics of nitroglycerin and long-acting nitrate esters.
Topics: Absorption; Dose-Response Relationship, Drug; Humans; Isosorbide Dinitrate; Kinetics; Nitrates; Nitroglycerin | 1983 |
Analysis of oral molsidomine effects on ventricular function and dimensions in the conscious dog.
Topics: Administration, Oral; Animals; Dogs; Female; Heart; Hemodynamics; Intestinal Absorption; Isosorbide Dinitrate; Male; Molsidomine; Nitroglycerin; Oxadiazoles; Sydnones; Vasodilator Agents | 1983 |
Coronary arteriographic findings during early hours of acute myocardial infarction: response to intracoronary injection of nitrates.
Topics: Adult; Aged; Arterial Occlusive Diseases; Coronary Angiography; Coronary Disease; Coronary Vasospasm; Coronary Vessels; Female; Humans; Injections, Intra-Arterial; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Urokinase-Type Plasminogen Activator | 1983 |
Vasodilators in the treatment of congestive heart failure.
Topics: Captopril; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Minoxidil; Nitroglycerin; Nitroprusside; Prazosin; Vasodilator Agents | 1983 |
Drug interactions with medical plastics.
Topics: Adsorption; Chlormethiazole; Chloroquine; Contact Lenses; Diazepam; Drug Packaging; Humans; Insulin; Isosorbide Dinitrate; Nitroglycerin; Plastics; Vitamin A | 1983 |
Different hemodynamic actions of trinitroglycerin and isosorbide dinitrate in patients with acute myocardial infarction.
Topics: Cardiac Output; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Pulmonary Wedge Pressure; Vascular Resistance | 1983 |
Loss of glyceryl trinitrate and of isosorbide dinitrate during infusion: a literature survey and practical recommendations.
Topics: Glass; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Nitroglycerin; Polyethylenes | 1983 |
Blood vessel uptake and metabolism of organic nitrates in the rat.
Topics: Animals; Aorta; Blood Vessels; Carbon Radioisotopes; Femoral Vein; Isosorbide Dinitrate; Kinetics; Male; Nitrates; Nitroglycerin; Rats; Rats, Inbred Strains; Time Factors; Vena Cava, Inferior | 1984 |
Nitrates in aortic valve disease: acute and chronic effects.
Topics: Aortic Valve Insufficiency; Aortic Valve Stenosis; Hemodynamics; Humans; Isosorbide Dinitrate; Nitroglycerin | 1983 |
In vivo and in vitro studies to elucidate the hemodynamic differences of sodium nitroprusside, nitroglycerin, and two isosorbide nitrates.
Topics: Animals; Blood Pressure; Ferricyanides; Hemodynamics; In Vitro Techniques; Isosorbide Dinitrate; Nitroglycerin; Nitroprusside; Rabbits; Rats; Rats, Inbred Strains; Renal Artery; Renal Veins | 1983 |
Intravenous nitroglycerin: clinical use and efficacy.
Topics: Angina Pectoris; Coronary Disease; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Ointments | 1984 |
Nitrates IV. Cardiovascular effects.
Topics: Heart Diseases; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1983 |
Haemodynamics and plasma concentrations following sublingual GTN and intravenous, or inhaled, isosorbide dinitrate.
Topics: Absorption; Cardiac Catheterization; Hemodynamics; Humans; Isosorbide Dinitrate; Kinetics; Male; Middle Aged; Nitroglycerin; Thorax; Time Factors | 1984 |
Hemodynamic and metabolic effects of vasodilator therapy for heart failure in acute myocardial infarction.
Topics: Blood Pressure; Cardiac Output; Coronary Circulation; Epoprostenol; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Molsidomine; Myocardial Infarction; Myocardium; Nitroglycerin; Oxygen Consumption; Sydnones; Vasodilator Agents | 1984 |
Methemoglobin levels produced by organic nitrates in patients with coronary artery disease.
Topics: Aged; Angina Pectoris; Angina, Unstable; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Male; Methemoglobin; Middle Aged; Nitrates; Nitroglycerin | 1984 |
On the haemodynamic differences between sodium nitroprusside, nitroglycerin, and isosorbide nitrates. Comparison of their vasorelaxant effects in vitro and of their inactivation in vivo.
Topics: Animals; Blood Pressure; Female; Ferricyanides; Hemodynamics; In Vitro Techniques; Infusions, Intra-Arterial; Infusions, Parenteral; Isosorbide Dinitrate; Male; Muscle, Smooth, Vascular; Nitroglycerin; Nitroprusside; Rabbits; Rats; Rats, Inbred Strains; Renal Artery; Renal Veins; Vasoconstriction; Vasodilation | 1984 |
[Clinical and hemodynamic effects of an isosorbide dinitrate tape on patients with congestive heart failure--comparative study with nitroglycerin ointment].
Topics: Adult; Aged; Dosage Forms; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Ointments; Time Factors | 1983 |
The effects of organic nitrates on prostacyclin biosynthesis and platelet function in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Angina Pectoris; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Epinephrine; Epoprostenol; Heart Rate; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Platelet Aggregation | 1984 |
Transdermal isosorbide dinitrate in angina pectoris: effect of acute and sustained therapy.
Topics: Administration, Topical; Angina Pectoris; Blood Pressure; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1984 |
Nitrates for angina pectoris. A critical review of therapeutic efficacy and tolerance.
Topics: Angina Pectoris; Drug Tolerance; Electrocardiography; Hemodynamics; Humans; Isosorbide Dinitrate; Long-Term Care; Nitrates; Nitroglycerin; Physical Exertion | 1984 |
[Long-term therapy with nitrates. Relation between dosage and tolerance effect].
Topics: Adult; Angina Pectoris; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Hemodynamics; Humans; Isosorbide Dinitrate; Long-Term Care; Middle Aged; Nitroglycerin | 1984 |
Determination of the partitioning, stability, and metabolite formation of isosorbide dinitrate in human and rat blood using an improved gas-liquid chromatographic assay.
Topics: Animals; Chromatography, Gas; Drug Stability; Humans; Isosorbide Dinitrate; Kinetics; Male; Nitroglycerin; Rats; Rats, Inbred Strains; Solubility | 1984 |
[Comparison of isosorbide dinitrate and nitroglycerin in patients with angina pectoris].
Topics: Angina Pectoris; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1984 |
[Ambulatory treatment of chronic heart failure with peripheral vasodilators].
Topics: Ambulatory Care; Chronic Disease; Drug Therapy, Combination; Heart Failure; Humans; Isosorbide Dinitrate; Nitroglycerin; Vasodilator Agents | 1984 |
Investigations into the development of tolerance to organic nitrates in conscious dogs.
Topics: Animals; Blood Pressure; Dogs; Drug Tolerance; Female; Hemodynamics; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin; Time Factors | 1984 |
Treatment of unstable angina with emphasis on calcium antagonists.
Topics: Angina Pectoris; Angina, Unstable; Anticoagulants; Coronary Circulation; Coronary Disease; Electrocardiography; Humans; Isosorbide Dinitrate; Metoprolol; Nifedipine; Nitroglycerin; Oxygen Consumption; Propranolol; Verapamil | 1984 |
Sublingual isosorbide dinitrate, topical isosorbide dinitrate and topical nitroglycerine in salvaging ischaemic myocardium.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Coronary Disease; Electrocardiography; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin | 1984 |
Stimulation of vascular PGI2 by organic nitrates and its significance for the antianginal effect.
Topics: Angina Pectoris; Animals; Blood Platelets; Coronary Vessels; Epoprostenol; Humans; Isosorbide Dinitrate; Nitroglycerin; Platelet Aggregation; Stimulation, Chemical; Thromboxane A2 | 1984 |
The effect of nitroglycerin and isosorbiddinitrate on myocardial perfusion and hemodynamics in patients with and without coronary disease.
Topics: Blood Flow Velocity; Blood Pressure; Cardiac Pacing, Artificial; Coronary Artery Bypass; Coronary Circulation; Coronary Disease; Graft Occlusion, Vascular; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Nitroglycerin; Physical Exertion; Stroke Volume | 1984 |
Nitrates in heart failure. Pathophysiological mechanisms and therapeutic applications.
Topics: Cardiac Output; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Hydralazine; Isosorbide Dinitrate; Muscle, Smooth, Vascular; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption; Pulmonary Wedge Pressure; Vasodilation | 1984 |
Treatment of coronary heart disease with isosorbide mononitrate ('Elantan' 20): a multi-centre study in hospital and general practice.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin | 1984 |
[Drug therapy of coronary disease. Nitrates in acute and longtime therapy].
Topics: Coronary Disease; Headache; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Time Factors | 1980 |
[Long-term treatment of coronary disease with nitrates. The prescribed dosage is mostly too low].
Topics: Coronary Disease; Dose-Response Relationship, Drug; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1980 |
Organic nitrate therapy in glaucoma.
Topics: Administration, Oral; Dose-Response Relationship, Drug; Glaucoma; Humans; Infusions, Parenteral; Intraocular Pressure; Isosorbide Dinitrate; Nitroglycerin | 1980 |
Effect of sublingual nitroglycerin and long-acting nitrate preparations on esophageal motility.
Topics: Adult; Esophagogastric Junction; Esophagus; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Pentagastrin | 1980 |
Hemodynamic effects of nitrates in chronic heart failure and myocardial infarction.
Topics: Chronic Disease; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitrates; Nitroglycerin; Oxygen Consumption; Vasodilator Agents | 1980 |
[Are nitrate compounds effective when administered orally? Results of pharmacokinetic and hemodynamic studies].
Topics: Administration, Oral; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilator Agents | 1980 |
Nitrate tolerance and dependence. A critical assessment.
Topics: Angina Pectoris; Animals; Dogs; Drug Tolerance; Heart Failure; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Rabbits; Rats; Substance-Related Disorders; Tachyphylaxis; Vasodilator Agents | 1980 |
[Use of nitroglycerin and nitrate esters in angina pectoris and acute myocardial infarct].
Topics: Acute Disease; Angina Pectoris; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin | 1980 |
Clinical effects of a sustained-release preparation of isosorbide dinitrate on angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Delayed-Action Preparations; Electrocardiography; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1980 |
[The use of organic nitrates to lower intraocular pressure in outpatient and surgical treatment (author's transl)].
Topics: Dose-Response Relationship, Drug; Glaucoma; Humans; Intraocular Pressure; Isosorbide Dinitrate; Nitroglycerin; Preoperative Care | 1980 |
[Development of tolerance to the hemodynamic effects of nitroglycerin].
Topics: Adult; Blood Pressure; Drug Tolerance; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Vascular Resistance | 1980 |
Current status of hemodynamic monitoring: indication, diagnoses, complications.
Topics: Acute Disease; Arrhythmias, Cardiac; Cardiac Output; Glucose; Heart Failure; Heart Ventricles; Hemodynamics; Humans; Insulin; Isosorbide Dinitrate; Monitoring, Physiologic; Myocardial Infarction; Nitroglycerin; Potassium; Prognosis; Shock, Cardiogenic; Stroke Volume | 1981 |
[The immediate treatment of acute myocardial infarct].
Topics: Acute Disease; Arrhythmias, Cardiac; First Aid; Furosemide; Hemodynamics; Humans; Isosorbide Dinitrate; Lidocaine; Myocardial Infarction; Nitroglycerin; Oxygen Inhalation Therapy; Pain; Shock, Cardiogenic | 1981 |
Verapamil therapy in variant angina pectoris refractory to nitrates.
Topics: Adult; Aged; Angina Pectoris; Angina Pectoris, Variant; Electrocardiography; Ergonovine; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Verapamil | 1981 |
Treatment of angina pectoris patients with niludipine a new calcium antagonistic drug.
Topics: Aged; Angina Pectoris; Electrocardiography; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Nitroglycerin; Pyridines | 1981 |
Nitrates, package inserts, and the Food and Drug Administration. A clinical paradox.
Topics: Angina Pectoris; Biological Availability; Delayed-Action Preparations; Drug Labeling; Heart Failure; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; United States; United States Food and Drug Administration; Vasodilator Agents | 1981 |
Effects of molsidomine, nitroglycerin, and isosorbide dinitrate on the coronary circulation, myocardial oxygen consumption, and haemodynamics in anaesthetized dogs.
Topics: Animals; Cardiovascular Agents; Coronary Circulation; Dogs; Female; Heart; Hemodynamics; Isosorbide Dinitrate; Male; Molsidomine; Morpholines; Myocardium; Nitroglycerin; Oxadiazoles; Oxygen Consumption; Sydnones | 1981 |
Nitrate-induced transient ischemic attacks.
Topics: Humans; Ischemic Attack, Transient; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1981 |
Coronary arterial spasm in single coronary artery.
Topics: Coronary Angiography; Coronary Vasospasm; Diltiazem; Electrocardiography; Ergonovine; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pain; Thorax | 1981 |
Central and regional hemodynamic effects of intravenous isosorbide dinitrate, nitroglycerin and nitroprusside in patients with congestive heart failure.
Topics: Cardiac Output; Extremities; Female; Ferricyanides; Heart Failure; Hemodynamics; Humans; Injections, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Nitroprusside; Oxygen Consumption; Stroke Volume; Systole | 1981 |
Comparison of sublingual nitroglycerine and isosorbide dinitrate ointment by radionuclide ventriculography.
Topics: Adult; Cardiac Output; Coronary Disease; Diagnosis, Differential; Exercise Test; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Mouth Floor; Nitroglycerin; Ointments | 1981 |
Management of unstable angina pectoris.
Topics: Administration, Oral; Angina Pectoris, Variant; Coronary Angiography; Coronary Artery Bypass; Coronary Vasospasm; Delayed-Action Preparations; Electrocardiography; Exercise Test; Hospitalization; Humans; Isosorbide Dinitrate; Mouth Floor; Nitroglycerin | 1982 |
Vasodilator therapy in refractory congestive heart failure: a comparative analysis of hemodynamic and noninvasive studies.
Topics: Aged; Cardiac Output; Drug Evaluation; Echocardiography; Female; Heart Failure; Hemodynamics; Humans; Hydralazine; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Ointment Bases; Prazosin; Pulmonary Wedge Pressure; Stroke Volume; Vasodilator Agents | 1982 |
Plastic syringes and intravenous infusions.
Topics: Chlormethiazole; Diazepam; Humans; Injections, Intravenous; Isosorbide Dinitrate; Nitroglycerin; Plastics; Polypropylenes; Syringes | 1981 |
Benefits from adding nifedipine to the treatment of unstable angina when beta-blockade and isosorbide dinitrate have proved inadequate.
Topics: Aged; Angina Pectoris, Variant; Coronary Disease; Coronary Vasospasm; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Nifedipine; Nitroglycerin; Physical Exertion; Propanolamines; Pyridines | 1982 |
Coronary artery spasm: recognition and treatment.
Topics: Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Coronary Angiography; Coronary Vasospasm; Diagnosis, Differential; Electrocardiography; Ergonovine; Humans; Isosorbide Dinitrate; Methacholine Compounds; Nitroglycerin; Propranolol | 1981 |
[Comparison between the hemodynamic effects of nitroglycerine ointment and oral isosorbide dinitrate in the treatment of left ventricular failure (author's transl)].
Topics: Administration, Oral; Adult; Aged; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Ointments | 1981 |
Managing angina with nitrates.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Angina Pectoris, Variant; Capsules; Delayed-Action Preparations; Humans; Injections, Intravenous; Isosorbide Dinitrate; Mouth Floor; Nitrates; Nitroglycerin; Ointments; Tablets | 1982 |
[Therapy of instable angina pectoris].
Topics: Angina Pectoris; Coronary Care Units; Diltiazem; Humans; Intra-Aortic Balloon Pumping; Isosorbide Dinitrate; Nifedipine; Nitroglycerin; Propranolol | 1982 |
[Trinitroglycerin ointment and oral isosorbide dinitrate: comparison of the hemodynamic effects induced in acute myocardial infarct with left ventricular insufficiency].
Topics: Aged; Female; Heart Failure; Heart Ventricles; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin | 1981 |
Unloading effects of vasodilators on peripheral circulation and cardiac hemodynamics in patients with acute myocardial infarction.
Topics: Adult; Aged; Female; Heart; Hemodynamics; Humans; Isosorbide Dinitrate; Leg; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Plethysmography; Prazosin; Regional Blood Flow; Stroke Volume; Vascular Resistance; Vasodilator Agents | 1982 |
Distal vasoconstriction following coronary angioplasty--comparison of emergent and elective PTCA.
Topics: Aged; Angioplasty, Balloon, Coronary; Coronary Vessels; Emergencies; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Vasoconstriction; Vasodilator Agents | 1995 |
Synthesis and pharmacology of a series of new organic nitrate esters.
Topics: Animals; Esters; Hemodynamics; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin; Rabbits; Rats; Rats, Wistar; Structure-Activity Relationship; Vasodilator Agents | 1995 |
GSH-independent denitration of organic nitrate esters in rabbit hepatic and vascular cytosol.
Topics: Animals; Blood Vessels; Cytosol; Ethylmaleimide; Glutathione; Isosorbide Dinitrate; Liver; Nitroglycerin; Rabbits | 1995 |
The rationale for nitrates in angina pectoris.
Topics: Angina Pectoris; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Humans; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin; Patient Compliance; Vasodilator Agents | 1995 |
Antioxidative action of the nitrovasodilator nicorandil: inhibition of oxidative activation of liver microsomal glutathione S-transferase and lipid peroxidation.
Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione Transferase; Isosorbide Dinitrate; Lipid Peroxidation; Male; Microsomes, Liver; Niacinamide; Nicorandil; Nitroglycerin; Oxidation-Reduction; Propanolamines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Structure-Activity Relationship; Sympathetic Nervous System; Vasodilator Agents | 1994 |
A clinical and in vitro study on the possible interaction of intravenous nitrates with heparin anticoagulation.
Topics: Angina, Unstable; Drug Interactions; Drug Therapy, Combination; Female; Heparin; Humans; In Vitro Techniques; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Partial Thromboplastin Time; Prospective Studies | 1994 |
Drugs for stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Humans; Isosorbide Dinitrate; Nitroglycerin; Vasodilator Agents | 1994 |
Extending a Bayesian analysis of the two-period crossover to allow for baseline measurements.
Topics: Administration, Cutaneous; Administration, Oral; Angina Pectoris; Bayes Theorem; Clinical Trials as Topic; Delayed-Action Preparations; Humans; Isosorbide Dinitrate; Models, Statistical; Nitroglycerin; Randomized Controlled Trials as Topic; Treatment Outcome | 1994 |
Influence of endothelium and nitrovasodilators on free thiols and disulfides in porcine coronary smooth muscle.
Topics: Analysis of Variance; Animals; Coronary Vessels; Cysteine; Disulfides; Drug Tolerance; Endothelium, Vascular; Histocytochemistry; In Vitro Techniques; Isosorbide Dinitrate; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Sulfhydryl Compounds; Swine; Vasodilator Agents | 1993 |
Effect of prolonged nitrate therapy on left ventricular remodeling after canine acute myocardial infarction.
Topics: Animals; Dogs; Echocardiography; Female; Hypertrophy, Left Ventricular; Isosorbide Dinitrate; Male; Myocardial Infarction; Myocardium; Nitroglycerin; Time Factors; Ventricular Function, Left | 1994 |
Pulmonary function tests in patients with congestive heart failure: effects of medical therapy.
Topics: Adult; Aged; Captopril; Cardiovascular Agents; Digoxin; Dobutamine; Drug Therapy, Combination; Echocardiography, Doppler; Forced Expiratory Volume; Furosemide; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Nitroprusside; Vasodilator Agents; Vital Capacity | 1993 |
Release of nitric oxide from glyceryl trinitrate by captopril but not enalaprilat: in vitro and in vivo studies.
Topics: Acetylcysteine; Animals; Captopril; Cattle; Enalapril; Endothelium, Vascular; Glutathione; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitroglycerin; Platelet Aggregation; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
[The efficacy of nitrate solutions in emergency states].
Topics: Angina Pectoris; Drug Evaluation; Emergencies; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Solutions | 1993 |
Nitric oxide promotes DNA synthesis and cyclic GMP formation in endothelial cells from postcapillary venules.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Coronary Vessels; Cyclic GMP; DNA; DNA Replication; Endothelium, Vascular; Fibroblast Growth Factor 2; Isosorbide Dinitrate; Kinetics; Nitric Oxide; Nitroglycerin; Nitroprusside; omega-N-Methylarginine; Thymidine; Venules | 1993 |
Platelet cyclic GMP. A potentially useful indicator to evaluate the effects of nitroglycerin and nitrate tolerance.
Topics: Atrial Natriuretic Factor; Blood Platelets; Coronary Angiography; Coronary Vessels; Cyclic GMP; Drug Tolerance; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Vasodilation | 1993 |
Solving the mystery of nitrate tolerance. A new scent on the trail?
Topics: Blood Platelets; Coronary Vessels; Cyclic GMP; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitroglycerin; Vasodilation | 1993 |
The effect of nitric oxide-donating vasodilators on monocyte chemotaxis and intracellular cGMP concentrations in vitro.
Topics: Cell Migration Inhibition; Chemotaxis, Leukocyte; Cyclic GMP; Humans; Isosorbide Dinitrate; Molsidomine; Monocytes; Nitroglycerin; Nitroprusside; Vasodilator Agents | 1993 |
Human endothelial cells bioactivate organic nitrates to nitric oxide: implications for the reinforcement of endothelial defence mechanisms.
Topics: Biotransformation; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Humans; Isosorbide Dinitrate; Nitrates; Nitric Oxide; Nitroglycerin; Platelet Aggregation; Time Factors | 1995 |
Role of collateral flow in a pharmacological stress test (a combination of low-dose dobutamine and a vasodilator) as a predictor of wall motion reversibility.
Topics: Adolescent; Adult; Aged; Angioplasty, Balloon, Coronary; Cardiotonic Agents; Collateral Circulation; Coronary Angiography; Coronary Circulation; Coronary Disease; Dobutamine; Drug Synergism; Female; Follow-Up Studies; Heart Ventricles; Humans; Isosorbide Dinitrate; Male; Middle Aged; Motion; Myocardial Contraction; Myocardial Stunning; Nitroglycerin; Observer Variation; Systole; Tomography, X-Ray Computed; Vasodilator Agents | 1995 |
Specificity of different organic nitrates to elicit NO formation in rabbit vascular tissues and organs in vivo.
Topics: Animals; Aorta; Blood Vessels; Cysteine; Cytochrome P-450 Enzyme System; Dipeptides; Electron Spin Resonance Spectroscopy; Guanylate Cyclase; In Vitro Techniques; Isometric Contraction; Isosorbide Dinitrate; Kidney; Liver; Muscle Relaxation; Nitrates; Nitric Oxide; Nitroglycerin; Rabbits; Sensitivity and Specificity; Solubility; Sulfhydryl Compounds; Vasodilator Agents; Venae Cavae | 1995 |
Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes.
Topics: Animals; Cells, Cultured; Cyclic GMP; Electric Stimulation; Heart Ventricles; Hydrazines; Isosorbide Dinitrate; Male; Myocardial Contraction; Nitrogen Oxides; Nitroglycerin; Penicillamine; Pentaerythritol Tetranitrate; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1996 |
Nitrate tolerance--problems both new and old.
Topics: Administration, Cutaneous; Administration, Oral; Angina Pectoris; Delayed-Action Preparations; Drug Tolerance; Heart Failure; Humans; Injections, Intravenous; Isosorbide Dinitrate; Myocardial Ischemia; Nitroglycerin; Vasodilator Agents | 1996 |
[Therapeutic range of transdermal nitro-patches].
Topics: Administration, Cutaneous; Angina Pectoris; Arrhythmias, Cardiac; Evaluation Studies as Topic; Heart Diseases; Heart Failure; Heart Rupture; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Recurrence; Time Factors; Vasodilator Agents | 1995 |
Surgery for left main spasm. Is it indicated?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Surgical Procedures; Chest Pain; Coronary Angiography; Coronary Vasospasm; Diltiazem; Drug Therapy, Combination; Felodipine; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Vasodilator Agents | 1996 |
Impaired effectiveness of nitric oxide-donors in resistance arteries of patients with arterial hypertension.
Topics: Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; Forearm; Humans; Hypertension; Isosorbide Dinitrate; Middle Aged; Nitric Oxide; Nitroglycerin; Nitroprusside; Plethysmography; Vascular Resistance; Vasodilator Agents | 1996 |
Evaluation of nitric oxide formation from nitrates in pig coronary arteries.
Topics: Animals; Coronary Vessels; Cysteine; Glutathione Transferase; In Vitro Techniques; Isosorbide Dinitrate; Liver; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Swine; Vasodilation | 1996 |
ITF 296, a new endothelium-independent vasodilator: comparison with nitroglycerin and isosorbide dinitrate.
Topics: Animals; Benzoxazines; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemodynamics; Isosorbide Dinitrate; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Oxazines; Vasodilator Agents | 1995 |
Mechanism of ITF 296-induced vasorelaxation compared to nitroglycerin and isosorbide dinitrate: relationship between relaxation of rabbit aorta and tissue cGMP.
Topics: Animals; Aorta, Thoracic; Benzoxazines; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Oxazines; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
[Cardicap treatment of ischemic heart disease in aged patients].
Topics: Administration, Oral; Echocardiography; Electrocardiography, Ambulatory; Exercise Test; Female; Follow-Up Studies; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Time Factors; Treatment Outcome; Vasodilator Agents | 1997 |
Effects of enalapril during continuous nitrate therapy: analysis of diameter of coronary arteries and platelet cyclic guanosine monophosphate.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Platelets; Case-Control Studies; Coronary Angiography; Coronary Disease; Coronary Vessels; Cyclic GMP; Drug Administration Schedule; Enalapril; Female; Humans; Hypertension; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Norepinephrine; Renin; Vasodilator Agents | 1997 |
Effect of organic nitrates on ex vivo platelet aggregation and fibrinolysis in man.
Topics: Adenosine Diphosphate; Adult; Blood Pressure; Cross-Over Studies; Double-Blind Method; Fibrinolysis; Heart Rate; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Nitroglycerin; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Tissue Plasminogen Activator; Vasodilator Agents | 1996 |
[The possibility of the development of isosorbide dinitrate and nifedipine withdrawal syndromes in patients with stable stenocardia of effort].
Topics: Adult; Aged; Angina Pectoris; Exercise Tolerance; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Nitroglycerin; Physical Exertion; Substance Withdrawal Syndrome; Time Factors; Vasodilator Agents | 1997 |
[Heart in the pants: treatment of chronic anal fissure with nitrate ointment].
Topics: Administration, Rectal; Double-Blind Method; Fissure in Ano; Humans; Isosorbide Dinitrate; Nitroglycerin; Ointments; Randomized Controlled Trials as Topic; Treatment Outcome; Vasodilator Agents | 1997 |
[Sublingual isosorbide-5 mononitrate during coronary arteriography. Comparison with sublingual nitroglycerin].
Topics: Administration, Sublingual; Blood Pressure; Cardiac Catheterization; Cineangiography; Coronary Vessels; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Vasodilator Agents | 1997 |
[Comparative efficacy, safety, cardio-hemodynamic effects of isosorbide dinitrate (ID) aerosol and sublingual tablets of nitroglycerin].
Topics: Administration, Inhalation; Administration, Sublingual; Aerosols; Aged; Angina Pectoris; Electrocardiography; Exercise Tolerance; Female; Follow-Up Studies; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Safety; Treatment Outcome; Vasodilator Agents | 1998 |
Tailored therapy using dobutamine and nitroglycerin in advanced heart failure.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Cardiotonic Agents; Dobutamine; Female; Heart Failure; Hemodynamics; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Infusions, Parenteral; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Retrospective Studies; Treatment Outcome; Vasodilator Agents | 1999 |
Nitric oxide generation, tachyphylaxis and cross-tachyphylaxis from nitrovasodilators in vivo.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Isosorbide Dinitrate; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Rabbits; Tachyphylaxis; Vasodilator Agents | 1999 |
Effects of the flavoprotein inhibitor, diphenyleneiodonium sulfate, on ex vivo organic nitrate tolerance in the rat.
Topics: Animals; Aorta, Thoracic; Biotransformation; Blotting, Northern; Drug Tolerance; Enzyme Inhibitors; Flavoproteins; Glutathione; Isosorbide Dinitrate; Male; Microsomes; Muscle, Smooth, Vascular; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; Nitroso Compounds; Onium Compounds; Prodrugs; Rats; Rats, Sprague-Dawley; S-Nitrosoglutathione; Stereoisomerism; Superoxides; Vasodilator Agents | 2000 |
[Role of nitrates in the treatment of ischemia].
Topics: Angina Pectoris; Coronary Disease; Emergencies; Humans; Hypotension, Orthostatic; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Time Factors; Vasodilator Agents | 2000 |
Effect of isosorbide dinitrate on nitric oxide synthase under hypoxia.
Topics: Animals; Citrulline; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Isosorbide Dinitrate; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Oxygen; Oxyhemoglobins; Swine | 2001 |
Influence of nitrovasodilators and cyclooxygenase inhibitors on cerebral vasoreactivity in conscious rabbits.
Topics: Acetazolamide; Animals; Blood Pressure; Blood Vessels; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Humans; Hypercapnia; Indomethacin; Isosorbide Dinitrate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Rabbits; Signal Transduction; Telencephalon; Vasodilation | 2001 |
Intermittent nitrate therapy for prior myocardial infaraction does not induce rebound angina nor reduce cardiac events.
Topics: Administration, Cutaneous; Administration, Oral; Aged; Angina Pectoris; Cardiovascular Agents; Coronary Vasospasm; Delayed-Action Preparations; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Drug Tolerance; Exercise Tolerance; Female; Follow-Up Studies; Heart Failure; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Recurrence; Retrospective Studies; Treatment Outcome | 2000 |
Acute congestive heart failure associated with a limited form of systemic sclerosis and primary biliary cirrhosis.
Topics: Acute Disease; Antibody Specificity; Autoantibodies; Autoimmune Diseases; Centromere; Coronary Circulation; Dyspnea; Female; Furosemide; Heart Failure; Humans; Isosorbide Dinitrate; Liver Cirrhosis, Biliary; Microcirculation; Microsomes, Liver; Middle Aged; Nitroglycerin; Radionuclide Imaging; Raynaud Disease; Scleroderma, Systemic; Skin; Thallium Radioisotopes | 2001 |
Vasoactive response of different parts of human internal thoracic artery to isosorbide-dinitrate and nitroglycerin: an in-vitro study.
Topics: Analysis of Variance; Coronary Artery Bypass; Culture Techniques; Dose-Response Relationship, Drug; Humans; Isosorbide Dinitrate; Mammary Arteries; Nitroglycerin; Probability; Sensitivity and Specificity; Vasodilation; Vasodilator Agents | 2001 |
Echocardiographical demonstration of a progressively expanding left ventricular aneurysm preceded by endomyocardial tearing.
Topics: Aged; Aneurysm, False; Antihypertensive Agents; Combined Modality Therapy; Coronary Disease; Disease Progression; Echocardiography; Endocardium; Female; Fibrin Tissue Adhesive; Heart Aneurysm; Heart Rupture; Heart Ventricles; Humans; Hypromellose Derivatives; Isosorbide Dinitrate; Methylcellulose; Myocardial Infarction; Nitroglycerin; Pericardial Effusion; Stroke Volume; Tissue Adhesives; Ventricular Remodeling | 2001 |
Nitrates and Viagra can be a deadly combination.
Topics: Coronary Circulation; Drug Synergism; Humans; Hypotension; Isosorbide Dinitrate; Male; Nitroglycerin; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents | 2001 |
Impact of reference-based pricing of nitrates on the use and costs of anti-anginal drugs.
Topics: Aged; Angina Pectoris; British Columbia; Cost Control; Cost Savings; Drug Costs; Drug Prescriptions; Economics, Pharmaceutical; Formularies as Topic; Health Policy; Humans; Isosorbide Dinitrate; Nitroglycerin; Prescription Fees; Rate Setting and Review; Vasodilator Agents | 2001 |
Escape from tolerance of organic nitrate by induction of cytochrome P450.
Topics: Animals; Blood Pressure; Blotting, Western; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Drug Tolerance; Enzyme Induction; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydrazines; Immunohistochemistry; Interleukin-1; Isoenzymes; Isosorbide Dinitrate; Kinetics; Male; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroglycerin; Nitroprusside; Rats; Rats, Wistar | 2001 |
Tolerance to nitroglycerin induced by isosorbide-5-mononitrate infusion in vivo.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Tolerance; Infusion Pumps, Implantable; Isosorbide Dinitrate; Male; Nitroglycerin; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2001 |
Anti-atherosclerotic effect of beta-blocker with nitric oxide-releasing action on the severe atherosclerosis.
Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Arteriosclerosis; Atenolol; Blood Pressure; Cholesterol; Cholesterol, Dietary; Endothelium, Vascular; Heart Rate; Isosorbide Dinitrate; Male; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; Propanolamines; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasodilator Agents | 2002 |
Penile erectile responses to cavernous nerve stimulation in rats are not affected by nitrate tolerance.
Topics: Animals; Blood Pressure; Drug Tolerance; Electric Stimulation; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin; Penile Erection; Rats | 2002 |
Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure (Br J Surg 2002; 89: 413-17).
Topics: Chronic Disease; Diltiazem; Fissure in Ano; Humans; Isosorbide Dinitrate; Nitric Oxide Donors; Nitroglycerin; Randomized Controlled Trials as Topic; Vasodilator Agents | 2002 |
Allergic reactions to glyceryl trinitrate and isosorbide dinitrate demonstrating cross-sensitivity.
Topics: Administration, Cutaneous; Drug Eruptions; Drug Interactions; Female; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Middle Aged; Myocardial Infarction; Nitroglycerin; Vasodilator Agents | 2002 |
Organic nitrate tolerance is induced by degradation of some cytochrome P450 isoforms.
Topics: Animals; Blotting, Western; Cytochrome P-450 CYP1A2; Humans; Immunohistochemistry; Isosorbide Dinitrate; Male; Nitrates; Nitric Oxide; Nitroglycerin; Protein Isoforms; Rats; Rats, Wistar; Time Factors; Vasodilator Agents | 2002 |
Prognostic value of nitrate enhanced Tc99m MIBI SPECT study in detecting viable myocardium in patients with coronary artery disease.
Topics: Coronary Artery Disease; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Prognosis; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed, Single-Photon; Ventricular Dysfunction, Left | 2003 |
Effects of a nitro compound patch on neuropathy in Churg-Strauss syndrome.
Topics: Adrenergic beta-Agonists; Asthma; Churg-Strauss Syndrome; Cyclophosphamide; Drug Hypersensitivity; Female; Heart Failure; Humans; Immunosuppressive Agents; Isosorbide Dinitrate; Middle Aged; Nitric Oxide Donors; Nitro Compounds; Nitroglycerin; Peroneal Neuropathies; Pulmonary Eosinophilia; Terbutaline; Theophylline; Vasodilator Agents | 2003 |
Nitroglycerin and isosorbide dinitrate in coronary insufficiency.
Topics: Anti-Arrhythmia Agents; Cardiotonic Agents; Coronary Artery Disease; Coronary Disease; Isosorbide Dinitrate; Nitroglycerin; Vasodilator Agents | 1961 |
Clinical evaluation of sublingual nitrates. Onset and duration of action of nitroglycerin and isosorbide dinitrate.
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Nitrates; Nitrites; Nitroglycerin; Vasodilator Agents | 1963 |
Nitric oxide donors inhibit the coxsackievirus B3 proteinases 2A and 3C in vitro, virus production in cells, and signs of myocarditis in virus-infected mice.
Topics: 3C Viral Proteases; Animals; Cell Line; Cysteine Endopeptidases; Enterovirus B, Human; Enterovirus Infections; HeLa Cells; Humans; Isosorbide Dinitrate; Mice; Myocarditis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroglycerin; Penicillamine; Viral Proteins; Virus Replication | 2004 |
Does nitric oxide mediate the vasodilator activity of nitroglycerin?
Topics: Animals; Aorta, Thoracic; Benomyl; Calcimycin; Cell Adhesion Molecules; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Ionophores; Isosorbide Dinitrate; Male; Microfilament Proteins; Nitric Oxide; Nitroglycerin; Phosphoproteins; Phosphorylation; Rabbits; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Renal Artery; Soluble Guanylyl Cyclase; Spin Trapping; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Venae Cavae | 2003 |
Continuous administration of organic nitrate decreases hepatic cytochrome P450.
Topics: Animals; Blotting, Western; Catalase; Cytochrome P-450 Enzyme System; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Isosorbide Dinitrate; Liver; Male; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroglycerin; Rats; Rats, Wistar | 2004 |
[Not just effective against symptoms of ischemia. Nitrates also improve prognosis].
Topics: Aged; Coronary Disease; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Nitroglycerin; Prognosis; Vasodilator Agents | 2002 |
Tolerance induction during therapy with long-acting nitrates: how extensive is the "collateral damage"?
Topics: Angina Pectoris; Delayed-Action Preparations; Drug Tolerance; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitrates; Nitric Oxide Donors; Nitroglycerin | 2004 |
The inhibitory effect of sodium nitroprusside on HIF-1 activation is not dependent on nitric oxide-soluble guanylyl cyclase pathway.
Topics: Animals; Cell Line; Cyclic N-Oxides; DNA-Binding Proteins; Free Radical Scavengers; Gene Expression Regulation; Guanylate Cyclase; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Isosorbide Dinitrate; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Nuclear Proteins; Oxygen; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Transcription Factors; Transcription, Genetic; Vasodilator Agents | 2004 |
Continuous treatment with organic nitrate affects hepatic cytochrome P450.
Topics: Animals; Blotting, Western; Cytochrome P-450 Enzyme System; Drug Tolerance; Isosorbide Dinitrate; Liver; Male; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitrites; Nitroglycerin; Protein Isoforms; Rats; Rats, Wistar | 2004 |
Reproducibility of nitrate-stimulated tilt testing in patients with suspected vasovagal syncope and a healthy control group.
Topics: Adolescent; Adult; Aged; Blood Pressure; Electrocardiography; Female; Heart Arrest; Heart Rate; Hemodynamics; Humans; Isoproterenol; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Patient Selection; Posture; Predictive Value of Tests; Reproducibility of Results; Sensitivity and Specificity; Syncope, Vasovagal; Tilt-Table Test | 2005 |
Nitroglycerin: a blast from the past remains a trusted standby. Nitrates offer quick, effective relief from a common heart disease symptom, often for just pennies per dose.
Topics: Angina Pectoris; Drug Interactions; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitroglycerin; Vasodilator Agents | 2005 |
Generalized gamma frailty model.
Topics: Angina Pectoris; Biometry; Databases, Factual; Humans; Isosorbide Dinitrate; Likelihood Functions; Models, Statistical; Monte Carlo Method; Nitroglycerin; Vasodilator Agents | 2006 |
[Effects of isosorbide-5-mononitrate on clinical condition, bicycle ergometry results, endothelium-dependent vasodilation in patients with ischemic heart disease with stable effort angina].
Topics: Adult; Aged; Angina Pectoris; Blood Flow Velocity; Brachial Artery; Endothelium, Vascular; Exercise Test; Exercise Tolerance; Follow-Up Studies; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Physical Exertion; Time Factors; Treatment Outcome; Ultrasonography; Vasodilation; Vasodilator Agents | 2005 |
Relation of coronary hypersensitivity to serotonin in cardiac transplant recipients to vessel wall morphology and effect of vitamin C.
Topics: Adult; Ascorbic Acid; Bradykinin; Coronary Vessels; Dietary Supplements; Heart Transplantation; Humans; Hyperplasia; Isosorbide Dinitrate; Middle Aged; Nitroglycerin; Oxidative Stress; Serotonin; Time Factors; Tunica Intima; Ultrasonography, Interventional | 2006 |
Cerebral vasodilatation to exogenous NO is a measure of fitness for life at altitude.
Topics: Acclimatization; Adult; Altitude Sickness; Black People; Blood Flow Velocity; Breath Tests; Carbon Dioxide; Cerebrovascular Circulation; Ethiopia; Hematocrit; Humans; Hypoxia, Brain; Indians, South American; Isosorbide Dinitrate; Male; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Oxygen; Peru; Physical Fitness; Selection, Genetic | 2006 |
An evidence-based treatment algorithm for anal fissure.
Topics: Algorithms; Fissure in Ano; Humans; Isosorbide Dinitrate; Nitric Oxide Donors; Nitroglycerin | 2006 |
Chemosensitization of cancer in vitro and in vivo by nitric oxide signaling.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cyclic GMP; Drug Resistance, Neoplasm; Female; Humans; Isosorbide Dinitrate; Male; Mice; Neoplasms, Experimental; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Prostatic Neoplasms; Signal Transduction | 2007 |
Combined use of PDE5 inhibitors and nitrates in the treatment of pulmonary arterial hypertension in patients with heart failure.
Topics: Cyclic GMP; Drug Therapy, Combination; Heart Failure; Humans; Hypertension, Pulmonary; Isosorbide Dinitrate; Male; Middle Aged; Nitro Compounds; Nitroglycerin; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Pulmonary Artery; Purines; Sildenafil Citrate; Sulfones; Vasodilation; Vasodilator Agents | 2009 |
[Cardiotoxicity induced by 5-fluorouracil or capecitabine].
Topics: Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Heart; Heart Diseases; Humans; Isosorbide Dinitrate; Nitroglycerin; Prodrugs; Risk Factors; Vasodilator Agents | 2010 |
Use of organic nitrates and the risk of hip fracture: a population-based case-control study.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Epidemiologic Methods; Female; Hip Fractures; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Odds Ratio; Population; Risk; Vasodilator Agents; Young Adult | 2010 |
Differences between nitrates: role of isosorbide 2-mononitrate.
Topics: Animals; Aorta; Coronary Circulation; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Female; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle, Smooth, Vascular; Nitroglycerin; Perfusion; Rabbits; Vasodilation; Vasodilator Agents | 2010 |
Comparison of nitrite compounds and carperitide for initial treatment of acute decompensated heart failure.
Topics: Aged; Aged, 80 and over; Atrial Natriuretic Factor; Female; Heart Failure; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Treatment Outcome | 2011 |
A case of recurrent ventricular tachycardia.
Topics: Aged; Atorvastatin; Cardiovascular Agents; Digoxin; Drug Therapy, Combination; Female; Furosemide; Heptanoic Acids; Humans; Isosorbide Dinitrate; Lisinopril; Nitroglycerin; Pyrroles; Recurrence; Tachycardia, Ventricular; Warfarin | 2011 |
Effects of cyanamide, an aldehyde dehydrogenase type 2 inhibitor, on glyceryl trinitrate- and isosorbide dinitrate-induced vasodilation in rabbit excised aorta and in anesthetized whole animal.
Topics: Aldehyde Dehydrogenase; Anesthesia; Animals; Aorta, Thoracic; Cyanamide; Enzyme Inhibitors; In Vitro Techniques; Isosorbide Dinitrate; Nitrites; Nitroglycerin; Rabbits; Vasodilation; Vasodilator Agents | 2013 |
The effect of peroxynitrite decomposition catalyst MnTBAP on aldehyde dehydrogenase-2 nitration by organic nitrates: role in nitrate tolerance.
Topics: Aldehyde Dehydrogenase; Animals; Aorta; Blood Platelets; Cyclic GMP; Drug Tolerance; Endothelium, Vascular; Humans; Hypotension; Isosorbide Dinitrate; Male; Metalloporphyrins; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Platelet Aggregation; Rats; Thrombin; Tyrosine; Vasodilator Agents | 2014 |
Diffuse three-vessel coronary artery spasm.
Topics: Atorvastatin; Coronary Vasospasm; Diagnosis, Differential; Diagnostic Imaging; Diltiazem; Drug Therapy, Combination; Electrocardiography; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pyrroles; Risk Factors; Vasodilator Agents | 2015 |
Intermittent Nitrate Use and Risk of Hip Fracture.
Topics: Aged; Angina, Stable; Female; Hip Fractures; Humans; Isosorbide Dinitrate; Kaplan-Meier Estimate; Male; Myocardial Ischemia; Nitroglycerin; Proportional Hazards Models; Vasodilator Agents | 2017 |
ST elevation myocardial infarction after coronary artery spasm with no clear trigger.
Topics: Amlodipine; Arrhythmias, Cardiac; Cardiopulmonary Resuscitation; Coronary Angiography; Coronary Vasospasm; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardiography; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Recurrence; ST Elevation Myocardial Infarction; Vasodilator Agents | 2017 |
Nitroglycerin application and coronary arteriogenesis.
Topics: Animals; Aorta, Thoracic; Aspirin; Coronary Occlusion; Coronary Vessels; Disease Models, Animal; Humans; Isosorbide Dinitrate; Male; Myocardial Infarction; Nitroglycerin; Random Allocation; Rats; Rats, Sprague-Dawley; Research Design | 2018 |
Nitrate allergy and desensitization in a patient with refractory angina.
Topics: Aged; Angina Pectoris; Desensitization, Immunologic; Drug Eruptions; Drug Hypersensitivity; Humans; Injections, Intradermal; Isosorbide Dinitrate; Male; Nitroglycerin; Skin Tests; Vasodilator Agents | 2019 |
Comparative analysis of cost-effectiveness between isosorbide-5-mononitrate and isosorbide: a retrospective real-world evaluation.
Topics: Administration, Sublingual; Aged; Aged, 80 and over; China; Coronary Disease; Cost-Benefit Analysis; Female; Health Care Costs; Humans; Hypotension; Incidence; Isosorbide; Isosorbide Dinitrate; Length of Stay; Male; Middle Aged; Nitric Oxide Donors; Nitroglycerin; Pragmatic Clinical Trials as Topic; Propensity Score; Retrospective Studies; Vasodilator Agents | 2020 |
Fluorescent sensing for some nitric oxide donors in dosage forms and biological matrices.
Topics: Isosorbide Dinitrate; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin | 2021 |
Endocrine disruption: Reproductive toxicity of glyceryl trinitrate and isosorbide mononitrate in male Wistar rats.
Topics: Animals; Isosorbide Dinitrate; Luteinizing Hormone; Male; Nitrates; Nitric Oxide; Nitroglycerin; Oxidative Stress; Rats; Rats, Wistar; Semen; Sperm Count; Sperm Motility; Spermatozoa; Testis; Testosterone | 2022 |