isosorbide dinitrate has been researched along with niacinamide in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (45.16) | 18.7374 |
| 1990's | 16 (51.61) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Murao, S; Uchida, Y; Yoshimoto, N | 1 |
| MacLeod, D; Suryapranata, H | 1 |
| Döring, G | 1 |
| Wagner, G | 1 |
| Henry, PJ; Horowitz, JD; Louis, WJ | 1 |
| Cadeddu, M; Cherchi, A; Lai, C; Lai, G; Onnis, E; Orani, E; Solinas, R | 1 |
| Karaki, H; Murakami, K; Urakawa, N | 1 |
| Kuromaru, O; Sakai, K | 2 |
| Holzmann, S; Kukovetz, WR | 1 |
| Kukovetz, WR; Romanin, C | 1 |
| Hader, S; Leitold, M | 1 |
| Araki, H; Hayata, N; Matsuguchi, T; Nakamura, M | 1 |
| Gross, GJ; Pieper, GM | 1 |
| Ohba, Y; Sakai, K; Shiraki, Y | 1 |
| Hellige, G; Hoeft, A; Hunneman, DH; Korb, H; Schraeder, R; Wolpers, HG | 1 |
| Akima, M; Hinohara, Y; Obatake, N; Sakai, K | 1 |
| Hirakawa, S; Ito, H | 1 |
| Belz, GG; Heinrich, J; Matthews, J; Wagner, G | 1 |
| Hoeks, AP; Kool, MJ; Reneman, RS; Spek, JJ; Struyker Boudier, HA; Van Bortel, LM; van Herwaarden, RH | 1 |
| Bueno, O; Zavecz, JH | 1 |
| Aniya, Y; Naito, A; Sakanashi, M | 1 |
| Adachi, H; Kodama, K; Mori, N; Saito, I | 1 |
| Kato, K | 1 |
| Drummer, C; Gerzer, R; Ivanova, K; Schaefer, M | 1 |
| Branzi, A; Galiè, N; Guarnieri, C; Magnani, B; Parlangeli, R; Traini, AM; Ussia, GP; Vaona, I; Zimarino, M | 1 |
| Ejima, J; Fujino, T; Kaji, Y; Kanaya, S; Kaneda, K; Maruyama, T; Moriyama, H; Niho, Y; Ohmura, I; Tsuda, Y | 1 |
| Bona, M; Marsico, F; Micheletti, T; Specchia, G | 1 |
| Aya, G; de La Coussaye, JE; Delye, B; Eledjam, JJ; Juan, JM; Péray, P; Robert, E; Sassine, A | 1 |
| Fukuyama, S; Hirasawa, Y; Kato, M; Kato, Y; Kita, Y; Nishino, S; Ohkubo, K; Ohno, M | 1 |
2 review(s) available for isosorbide dinitrate and niacinamide
| Article | Year |
|---|---|
Pharmacologic therapy of angina pectoris.
Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Aspirin; Calcium Channel Blockers; Drug Therapy, Combination; Enoximone; Heparin; Humans; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Piperazines; Ranolazine; Vasodilator Agents | 1995 |
Haemodynamic and clinical effects of an intravenous potassium channel opener--a review.
Topics: Administration, Sublingual; Angina, Unstable; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Vasodilator Agents | 1993 |
7 trial(s) available for isosorbide dinitrate and niacinamide
| Article | Year |
|---|---|
Antianginal and anti-ischemic efficacy of nicorandil in comparison with isosorbide-5-mononitrate and isosorbide dinitrate: results from two multicenter, double-blind, randomized studies with stable coronary heart disease patients.
Topics: Adult; Aged; Blood Pressure; Coronary Disease; Double-Blind Method; Drug Administration Schedule; Exercise; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents | 1992 |
Selected issues from an overview on nicorandil: tolerance, duration of action, and long-term efficacy.
Topics: Administration, Oral; Administration, Sublingual; Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Exercise; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Niacinamide; Nicorandil; Nitroglycerin | 1992 |
[A new anti-ischemic drug for the treatment of stable effort angina pectoris: nicorandil. Comparison with placebo and isosorbide-5-mononitrate].
Topics: Aged; Angina Pectoris; Double-Blind Method; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Niacinamide; Nicorandil; Placebos; Vasodilator Agents | 1991 |
Controlled comparison of the pharmacodynamic effects of nicorandil (SG-75) and isosorbide dinitrate in man.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Electrocardiography; Female; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Niacinamide; Nicorandil; Systole; Vasodilator Agents | 1984 |
Acute and subacute effects of nicorandil and isosorbide dinitrate on vessel wall properties of large arteries and hemodynamics in healthy volunteers.
Topics: Administration, Oral; Adolescent; Adult; Biomarkers; Blood Pressure; Brachial Artery; Carotid Arteries; Compliance; Cross-Over Studies; Double-Blind Method; Drug Tolerance; Echocardiography, Doppler; Femoral Artery; Heart Rate; Humans; Isosorbide Dinitrate; Male; Niacinamide; Nicorandil; Regression Analysis; Stroke Volume; Vascular Resistance; Vasodilator Agents | 1995 |
Coronary dilating effects of intracoronary nicorandil. Comparison with isosorbide dinitrate.
Topics: Angina Pectoris; Atrial Fibrillation; Cardiomyopathy, Hypertrophic; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Female; Humans; Isosorbide Dinitrate; Male; Myocardial Infarction; Niacinamide; Nicorandil; Sick Sinus Syndrome; Vasodilator Agents | 1995 |
[Clinical use of potassium channel activators in angina pectoris: efficacy and tolerance].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Humans; Isosorbide Dinitrate; Myocardial Ischemia; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents | 1995 |
22 other study(ies) available for isosorbide dinitrate and niacinamide
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effect of 2-nicotinamidethyl nitrate (SG 75) on coronary circulation.
Topics: Animals; Constriction, Pathologic; Coronary Circulation; Coronary Vessels; Diltiazem; Dogs; Heart Rate; Isosorbide Dinitrate; Ligation; Niacinamide; Nifedipine; Nitrates; Nitroglycerin; Papaverine; Vasodilator Agents; Verapamil | 1978 |
Nicorandil and cardiovascular performance in patients with coronary artery disease.
Topics: Administration, Sublingual; Coronary Circulation; Coronary Disease; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Niacinamide; Nicorandil; Vasodilation; Vasodilator Agents; Ventricular Function, Left | 1992 |
Nitrate tolerance induced by nicorandil or nitroglycerin is associated with minimal loss of nicorandil vasodilator activity.
Topics: Animals; Arteries; Cattle; Coronary Vessels; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Nitric Oxide; Nitroglycerin; Vasodilator Agents | 1990 |
Comparison of the inhibitory effects of nicorandil, nitroglycerin and isosorbide dinitrate on vascular smooth muscle of rabbit aorta.
Topics: Animals; Aorta; Calcium; Cyclic GMP; In Vitro Techniques; Ion Channels; Isosorbide Dinitrate; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Rabbits | 1987 |
Nitrate tolerance: comparison of nicorandil, isosorbide dinitrate, and nitroglycerin in anesthetized dogs.
Topics: Anesthesia; Animals; Coronary Circulation; Dogs; Drug Tolerance; Female; Infusions, Intravenous; Injections, Intra-Arterial; Isosorbide Dinitrate; Male; Niacinamide; Nicorandil; Nitroglycerin; Vasodilator Agents | 1987 |
Cyclic GMP in nicorandil-induced vasodilatation and tolerance development.
Topics: Acetylcysteine; Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Vasodilation; Vasodilator Agents | 1987 |
Guanylate cyclase activation by organic nitrates is not mediated via nitrite.
Topics: Enzyme Activation; Guanylate Cyclase; Isosorbide Dinitrate; Kinetics; Niacinamide; Nicorandil; Nitrates; Nitrites; Nitroglycerin; Sulfhydryl Compounds; Vasodilator Agents | 1988 |
Cardiovascular effects of isosorbide dinitrate infused intravenously into anaesthetized dogs.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Female; Hemodynamics; Infusions, Intravenous; Isosorbide Dinitrate; Male; Niacinamide; Nicorandil; Nitroglycerin; Stroke Volume | 1986 |
[Influence of antianginal drugs on Lypressin induced T-wave enhancement in the electrocardiogram of the rat].
Topics: Administration, Oral; Angina Pectoris; Animals; Coronary Vasospasm; Electrocardiography; Hypoxia; Isosorbide Dinitrate; Lypressin; Male; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Effects of nicorandil on rest and effort angina unresponsive to combination therapy with a calcium antagonist and oral nitrate.
Topics: Aged; Aged, 80 and over; Angina Pectoris; Diltiazem; Drug Resistance; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Niacinamide; Nicorandil; Nifedipine; Physical Exertion; Prospective Studies; Rest; Vasodilator Agents | 1987 |
Salutary action of nicorandil, a new antianginal drug, on myocardial metabolism during ischemia and on postischemic function in a canine preparation of brief, repetitive coronary artery occlusions: comparison with isosorbide dinitrate.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Dogs; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Hemodynamics; Isosorbide Dinitrate; Male; Myocardium; Niacinamide; Nicorandil; Oxygen; Recurrence | 1987 |
Comparative vasorelaxing profiles of nicorandil, isosorbide dinitrate and nitroglycerin in isolated coronary arteries of the dog.
Topics: Acetylcysteine; Animals; Coronary Vessels; Dinoprost; Dogs; Endothelium; Female; In Vitro Techniques; Isosorbide Dinitrate; Male; Methylene Blue; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Chloride; Prostaglandins F; Vasodilator Agents | 1987 |
Effectiveness of nicorandil in the preservation of myocardium stressed by transient ischemia and its influence on cardiac metabolism during coronary artery occlusion with subsequent reperfusion: a comparison with isosorbide dinitrate.
Topics: Animals; Coronary Disease; Coronary Vessels; Dogs; Fatty Acids, Nonesterified; Glucose; Heart; Hemodynamics; Isosorbide Dinitrate; Lactates; Lactic Acid; Ligation; Myocardium; Niacinamide; Nicorandil; Perfusion | 1985 |
Hypotensive effects and biotransformation of nicorandil, a new antianginal agent, administered to rats by different routes: comparison with nitroglycerin and isosorbide dinitrate.
Topics: Animals; Antihypertensive Agents; Biotransformation; Blood Pressure; Dogs; Guinea Pigs; In Vitro Techniques; Isosorbide Dinitrate; Liver; Macaca mulatta; Male; Niacinamide; Nicorandil; Nitroglycerin; Rats; Rats, Inbred Strains; Swine; Vasodilator Agents | 1984 |
Effects of vasodilators on the systemic capacitance vessels, a study with the measurement of the mean circulatory pressure in dogs.
Topics: Animals; Blood Pressure; Blood Vessels; Blood Volume; Cardiac Output; Diltiazem; Dogs; Heart Rate; Isosorbide Dinitrate; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Prazosin; Sydnones; Trapidil; Vascular Resistance; Vasodilator Agents; Venous Pressure; Verapamil | 1984 |
Antioxidative action of the nitrovasodilator nicorandil: inhibition of oxidative activation of liver microsomal glutathione S-transferase and lipid peroxidation.
Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione Transferase; Isosorbide Dinitrate; Lipid Peroxidation; Male; Microsomes, Liver; Niacinamide; Nicorandil; Nitroglycerin; Oxidation-Reduction; Propanolamines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Structure-Activity Relationship; Sympathetic Nervous System; Vasodilator Agents | 1994 |
Effects of a novel, selective and potent phosphodiesterase type V inhibitor, E4021, on myocardial ischemia in guinea pigs.
Topics: Animals; Drug Interactions; Electrocardiography; Guinea Pigs; Injections, Intravenous; Isosorbide Dinitrate; Male; Myocardial Ischemia; Niacinamide; Nicorandil; Nitro Compounds; Phosphodiesterase Inhibitors; Piperidines; Quinazolines; Vasodilator Agents; Vasopressins | 1994 |
Effects of nitric oxide-containing compounds on increases in cytosolic ionized Ca2+ and on aggregation of human platelets.
Topics: Calcium; Cytosol; Female; Humans; Isosorbide Dinitrate; Kinetics; Male; Niacinamide; Nicorandil; Nitric Oxide; Platelet Aggregation; Sydnones | 1993 |
Limitation of myocardial infarct size by nicorandil after sustained ischemia in pigs.
Topics: Animals; Blood Pressure; Cardiac Output; Female; Glutathione; Heart Rate; Isosorbide Dinitrate; Male; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Myocardium; Niacinamide; Nicorandil; Peroxidase; Potassium Channels; Pulmonary Wedge Pressure; Swine; Vascular Resistance; Vasodilator Agents; Ventricular Function, Left | 1995 |
Comparison of proarrhythmogenic effects of two potassium channel openers, levcromakalim (BRL 38227) and nicorandil (RP 46417): a high-resolution mapping study on rabbit heart.
Topics: Animals; Arrhythmias, Cardiac; Benzopyrans; Bradycardia; Cromakalim; Dose-Response Relationship, Drug; Electrophysiology; Heart; In Vitro Techniques; Isosorbide Dinitrate; Niacinamide; Nicorandil; Potassium Channels; Pyrroles; Rabbits; Tachycardia; Vasodilator Agents; Ventricular Fibrillation | 1997 |
Comparison of hemodynamic effects of nitric oxide (NO) donors with different NO-releasing properties in rats.
Topics: Animals; Blood Pressure; Enzyme Inhibitors; Hematocrit; Hemodynamics; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nitric Oxide; Nitrites; Nitro Compounds; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Vasodilator Agents | 1997 |