Compounds > isosorbide dinitrate
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isosorbide dinitrate and la 419

isosorbide dinitrate has been researched along with la 419 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (83.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arderiu, G; Escolar, G; Hernandez, MR; Pino, M; Serradell, M; Tonda, R1
Alonso, D; Fernández, AP; Martínez, A; Martínez-Murillo, R; Mourelle, M; Rodrigo, J; Salas, E; Serrano, J1
Fernández, AP; Martínez, A; Martínez-Murillo, R; Mourelle, M; Rodrigo, J; Salas, E; Serrano, J1
Badimon, JJ; Choi, BG; Ibanez, B; Salas, E; Vilahur, G; Viles-Gonzalez, JF; Zafar, MU1
Badimon, L; Padró, T; Pena, E; Vilahur, G1
Martín, MT; Mourelle, M; Porras, M; Terán, E; Vergara, P1
Paulis, L; Simko, F1
Delgado, C; Fernández-Velasco, M; Mourelle, M; Ruiz-Hurtado, G1
Acín, S; Arbonés-Mainar, JM; Arnal, C; Barranquero, C; Carnicer, R; Gascón, S; Guillén, N; Guzmán, MA; Mourelle, M; Navarro, MA; Osada, J1
Leslie, SJ; Megson, IL1
Badimon, L; Molins, B; Padro, T; Peña, E; Vilahur, G1
Giménez, F; Martin, MT; Mourelle, M1

Reviews

1 review(s) available for isosorbide dinitrate and la 419

ArticleYear
LA-419, a nitric-oxide donor for the treatment of cardiovascular disorders.
    Current opinion in investigational drugs (London, England : 2000), 2009, Volume: 10, Issue:3

    Topics: Animals; Antioxidants; Cardiovascular Agents; Cardiovascular Diseases; Disease Models, Animal; Drug Tolerance; Fibrinolytic Agents; Humans; Hypertrophy, Left Ventricular; Isosorbide Dinitrate; Myocardial Ischemia; Nitric Oxide Donors; Patents as Topic; Structure-Activity Relationship; Treatment Outcome

2009

Other Studies

11 other study(ies) available for isosorbide dinitrate and la 419

ArticleYear
Antithrombotic effect of a new nitric oxide donor (LA419) on experimental thrombogenesis.
    European journal of clinical investigation, 2005, Volume: 35, Issue:5

    Topics: Animals; Blood Platelets; Collagen; Fibrinolytic Agents; Horses; Humans; Isosorbide Dinitrate; Models, Biological; Nitric Oxide Donors; Platelet Activation; Platelet Adhesiveness; Rabbits; Thrombosis

2005
The nitric oxide donor LA 419 decreases ischemic brain damage.
    International journal of molecular medicine, 2007, Volume: 19, Issue:2

    Topics: Animals; Brain Ischemia; Calcium; Disease Models, Animal; Immunohistochemistry; Isosorbide Dinitrate; Magnetic Resonance Imaging; Male; Neurons; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Tyrosine

2007
The nitric oxide donor LA 419 decreases brain damage in a focal ischemia model.
    Neuroscience letters, 2007, Mar-26, Volume: 415, Issue:2

    Topics: Animals; Brain Injuries; Corpus Striatum; Disease Models, Animal; Ischemia; Isosorbide Dinitrate; Magnetic Resonance Imaging; Male; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Time Factors; Tyrosine

2007
A novel anti-ischemic nitric oxide donor (LA419) reduces thrombogenesis in healthy human subjects.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:6

    Topics: Abciximab; Adult; Antibodies, Monoclonal; Drug Evaluation, Preclinical; Female; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Isosorbide Dinitrate; Male; Nitric Oxide Donors; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Receptors, Fibrinogen; Thrombosis

2007
Protein disulphide isomerase-mediated LA419- NO release provides additional antithrombotic effects to the blockade of the ADP receptor.
    Thrombosis and haemostasis, 2007, Volume: 97, Issue:4

    Topics: Administration, Oral; Animals; Blood Coagulation; Clopidogrel; Disease Models, Animal; Drug Therapy, Combination; Female; Fibrinolytic Agents; Isosorbide Dinitrate; Nitric Oxide; Nitric Oxide Donors; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Disulfide-Isomerases; Proteomics; Purinergic P2 Receptor Antagonists; Random Allocation; Receptors, Purinergic P2; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Thrombosis; Ticlopidine; Vasodilator Agents

2007
The nitric oxide donor LA-419 [S-(6-Nitro-oxi-hexahydro-furo[3,2-b]furan-3-1-il)thioacetate] prevents intestinal dysmotility, bacterial translocation, and inflammation in a rat model of enteritis.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 324, Issue:2

    Topics: Animals; Bacterial Translocation; Disease Models, Animal; Enteritis; Gastrointestinal Motility; Inflammation; Intestinal Diseases; Isosorbide Dinitrate; Lymph Nodes; Male; Nitric Oxide Donors; Rats; Rats, Sprague-Dawley

2008
LA419, a novel nitric oxide donor, prevents cardiac remodeling via the endothelial nitric oxide synthase pathway: NO donors as a means of antiremodeling.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:6

    Topics: Animals; Blood Pressure; Humans; Hypertrophy, Left Ventricular; Isosorbide Dinitrate; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Ventricular Remodeling

2007
LA419, a novel nitric oxide donor, prevents pathological cardiac remodeling in pressure-overloaded rats via endothelial nitric oxide synthase pathway regulation.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:6

    Topics: Animals; Blood Pressure; Caveolin 3; Cyclic GMP; Fibrosis; HSP90 Heat-Shock Proteins; Hypertrophy, Left Ventricular; Isosorbide Dinitrate; Male; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Ventricular Remodeling

2007
Nitric oxide-releasing agent, LA419, reduces atherogenesis in apolipoprotein E-deficient mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 379, Issue:5

    Topics: Adipose Tissue; Animals; Apolipoproteins E; Atherosclerosis; Cholesterol; Homozygote; Intestines; Isosorbide Dinitrate; Liver; Male; Mice; Mice, Inbred Strains; Nitric Oxide; Nitric Oxide Donors; Triglycerides

2009
Proteomic signature of thrombin-activated platelets after in vivo nitric oxide-donor treatment: coordinated inhibition of signaling (phosphatidylinositol 3-kinase-γ, 14-3-3ζ, and growth factor receptor-bound protein 2) and cytoskeleton protein translocati
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:11

    Topics: Administration, Oral; Animals; Blood Platelets; Contractile Proteins; Cytoskeletal Proteins; Female; Filamins; Gelsolin; GRB2 Adaptor Protein; Isoenzymes; Isosorbide Dinitrate; Microfilament Proteins; Models, Animal; Nitric Oxide Donors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proteomics; Signal Transduction; Swine; Thrombin

2011
Treatment with LA-419 prevents monocrotaline-induced pulmonary hypertension and lung injury in the rat.
    Proceedings of the Western Pharmacology Society, 2011, Volume: 54

    Topics: Animals; Blood Pressure; Hypertension, Pulmonary; Isosorbide Dinitrate; Male; Monocrotaline; Nitric Oxide Donors; Rats; Rats, Wistar

2011