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isosorbide dinitrate and isosorbide-2-mononitrate

isosorbide dinitrate has been researched along with isosorbide-2-mononitrate in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	50 (67.57)	18.7374
1990's	18 (24.32)	18.2507
2000's	2 (2.70)	29.6817
2010's	4 (5.41)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Atanassova, R; Balansky, R; Boev, K; Spassov, G	1
Werkö, L	1
Fung, HL; Tzeng, TB	3
Keller-Stanislawski, B; Marschner, JP; Rietbrock, N	1
Araki, Y; Furuno, K; Gomita, Y	4
Diestelhorst, M; Hinzpeter, B; Krieglstein, GK	1
Bennett, BM; Booth, BP; Brien, JF; Elliott, DA; Marks, GS; McCans, JL; Nakatsu, K	1
Bernini, W; De Caterina, R; Giannessi, D; Lazzerini, G; Lombardi, M; Mazzone, A; Moscarelli, E; Weiss, M	1
Heidemann, R; Kaltenbach, M; Menke, G; Rietbrock, N; Satter, P; Schneider, W	1
Bernini, W; De Caterina, R; Giannessi, D; Mazzone, A	2
Bernini, W; De Caterina, R; Giannessi, D; Lazzerini, G; Lombardi, M; Mazzone, A	1
Liu, WY	1
Boertz, A; Bonn, R; Cawello, W; Dickmans, HA; Evers, J; Weiss, M	1
Fay, L; Michel, G; Prost, M	1
Berenger, FP; Cano, JP; Rolland, PH	1
Ahland, B; König, E; Schrör, K; Weiss, P	1
Bogaert, MG	2
Bogaert, MG; Bouckaert, J; Lefebvre, RA; Rosseel, MT	1
Laufen, H; Leitold, M; Wildfeuer, A	1
Eckel, L; Kaltenbach, M; Kober, G; Schneider, W; von Loh, D	1
Berenger, FP; Bodard, H; Friggi, A; Rolland, PH	1
Menke, G; Rietbrock, N; Schnellhammer, R	1
Burkhardt, H; Deuster, U; Loew, D; Rietbrock, N	1
Cano, JP; Frances, Y; Iliadis, A; Luccioni, R; Santoni, Y	1
Bacher, S; Beck, A; Kraupp, O; Raberger, G; Skoda, H	1
Knoll, J; Menke, G; Merz, PG; Rietbrock, N	1
Fung, HL	2
Rietbrock, N	1
Abshagen, U; Betzien, G; Endele, R; Kaufmann, B; Neugebauer, G	1
Galeazzi, RL; Straehl, P	1
Cayen, MN; Dvornik, D; Hicks, D; Karounis, J	1
Blasini, R; Brügmann, U; Reiniger, G; Rudolph, W	1
Bussmann, WD	1
Fung, HL; Morrison, RA	2
Galeazzi, RL; Soliva, M; Straehl, P	1
Bennett, BM; Brien, JF; Marks, GS; Nakatsu, K; Tam, GS; Van Alstyne, K	1
Georgieva, R; Mikhaĭlova, D; Naplatanova, D; Ognianova, V; Velikova, E	1
Chasseaud, LF; Darragh, A; Doyle, E; Lambe, RF; Taylor, T	1
Bogaert, MG; Bruyneel, K; Rosseel, MT	2
Aumann, M; Laufen, H; Leitold, M	1
Laufen, H; Leitold, M	1
Pommier, F; Sioufi, A	1
Cano, JP; Rolland, PH; Santoni, Y	1
Chasseaud, LF; Major, RM; Taylor, IW; Taylor, T	1
Kochsiek, K; Schanzenbächer, P	1
Schuster, P; Trieb, G; Wiechmann, HW	1
Degen, J; Geigenberger, A; Maier-Lenz, H	1
Kimura, T; Kogi, K; Saito, T; Tanaka, O	1
Dietmann, K; Sponer, G; Voss, E	1
Bartsch, W; Dietmann, K; Strein, K	1
Bussmann, WD; Kaltenbach, M; Reifart, F; Reifart, N	1
Boelaert, J; Bogaert, MG; Daneels, R; Rosseel, MT	1
Mukerjee, N; Pietruszko, R	1
Bonn, R; Fritschi, E; Hutt, V; Lutz, D; Pabst, G; Theodor, R	1
Araki, I; Hashimoto, Y; Kimura, F; Kou, H; Kushikata, T; Matsuki, A; Murakawa, T; Sato, T; Takagi, H	1
Andersson, A; Bröijersén, A; Hjemdahl, P; Larsson, PT; Wallén, NH	1
Buchberger, D; Häring, N; Läuter, J; Metzner, JE	1
György, K; Papp, JG; Parratt, JR; Rastegar, MA; Végh, A	1
David, V; Medvedovici, A; Udrescu, S	1
Bonadei, I; Caretta, G; Cas, LD; Raddino, R; Teli, M; Vizzardi, E	1
Guo, J; Guo, R; Jiang, Z; Li, R; Sun, Z; Wei, C; Yuan, G; Zhang, R	1
Afanas'ev, RV; Galkin, AA; Komarova, SN; Kovtun, VY; Semenova, LA; Ushakov, IB; Vasin, MV	1
Chu, T; Li, Y; Wang, C; Wang, J; Zhao, L	1

Reviews

5 review(s) available for isosorbide dinitrate and isosorbide-2-mononitrate

Article	Year
[Tolerance in treatment with nitrates]. Lakartidningen, 1992, Feb-26, Volume: 89, Issue:9 Topics: Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Risk Factors	1992
Pharmacokinetics of organic nitrates in man: an overview. European heart journal, 1988, Volume: 9 Suppl A Topics: Absorption; Administration, Cutaneous; Administration, Sublingual; Humans; Injections, Intravenous; Isosorbide Dinitrate; Nitroglycerin	1988
Nitrate formulations and drug delivery systems--an overview. Zeitschrift fur Kardiologie, 1985, Volume: 74 Suppl 4 Topics: Animals; Biological Availability; Drug Tolerance; Isosorbide Dinitrate; Kinetics; Nitrates; Nitroglycerin; Rats	1985
[Acute and long-term nitrate treatment of angina pectoris]. Zeitschrift fur Kardiologie, 1983, Volume: 72, Issue:6 Topics: Acute Disease; Administration, Oral; Angina Pectoris; Bandages; Drug Tolerance; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Long-Term Care; Mouth Floor; Nitroglycerin; Ointments	1983
Clinical pharmacokinetics of nitrates. Cardiovascular drugs and therapy, 1994, Volume: 8, Issue:5 Topics: Angina Pectoris; Delayed-Action Preparations; Drug Administration Routes; Half-Life; Humans; Isosorbide Dinitrate; Liver; Nitrates; Nitroglycerin; Structure-Activity Relationship; Vasodilation; Vasodilator Agents	1994

Trials

12 trial(s) available for isosorbide dinitrate and isosorbide-2-mononitrate

Article	Year
[Pharmacokinetics of low-dose isosorbide dinitrate and metabolites after buccal or oral administration]. Arzneimittel-Forschung, 1992, Volume: 42, Issue:1 Topics: Administration, Buccal; Administration, Oral; Adult; Biological Availability; Blood Pressure; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male	1992
The effect of isosorbide-mononitrate eye drops on the human intraocular pressure and aqueous humor dynamics. International ophthalmology, 1991, Volume: 15, Issue:4 Topics: Aqueous Humor; Double-Blind Method; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Isosorbide Dinitrate; Middle Aged; Ocular Hypertension; Ophthalmic Solutions	1991
Inhibition of platelet function during in vivo infusion of isosorbide mononitrates: relationship between plasma drug concentration and hemodynamic effects. American heart journal, 1990, Volume: 119, Issue:4 Topics: Coronary Disease; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2	1990
In vivo actions of organic nitrates on platelet function in humans. Zeitschrift fur Kardiologie, 1989, Volume: 78 Suppl 2 Topics: Dose-Response Relationship, Drug; Epoprostenol; Humans; Isosorbide Dinitrate; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Vasodilator Agents	1989
[Dose-dependent serum concentration of ISDN and its metabolites following administration of ISDN-retard. Studies under steady-state conditions]. Deutsche medizinische Wochenschrift (1946), 1986, Nov-28, Volume: 111, Issue:48 Topics: Aged; Clinical Trials as Topic; Coronary Disease; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Humans; Isosorbide Dinitrate; Male; Random Allocation	1986
[Bioavailability of isosorbide dinitrate and isosorbide-5-mononitrate under steady-state conditions]. Deutsche medizinische Wochenschrift (1946), 1985, Nov-22, Volume: 110, Issue:47 Topics: Adult; Biological Availability; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Isosorbide Dinitrate; Male; Random Allocation	1985
Is isosorbide mononitrate better than the dinitrate? Drug and therapeutics bulletin, 1984, Jan-27, Volume: 22, Issue:2 Topics: Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Humans; Isosorbide Dinitrate	1984
[Prevention of the development of tolerance to isosorbide dinitrate in interval therapy]. Herz, 1984, Volume: 9, Issue:3 Topics: Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Electrocardiography; Heart Rate; Humans; Isosorbide Dinitrate	1984
[Comparison of the anti-angina effect and effect duration of isosorbide dinitrate, isosorbide-2-mononitrate (IS-2-MN) and isosorbide-5-mononitrate (IS-5-MN)]. Die Medizinische Welt, 1981, Apr-07, Volume: 32, Issue:14A Topics: Angina Pectoris; Delayed-Action Preparations; Hemodynamics; Humans; Isosorbide Dinitrate; Male	1981
Bioavailability and pharmacokinetics of a new isosorbide dinitrate spray preparation in healthy volunteers. Arzneimittel-Forschung, 1993, Volume: 43, Issue:8 Topics: Adolescent; Adult; Aerosols; Biological Availability; Chromatography, Gas; Humans; Isosorbide Dinitrate; Male; Therapeutic Equivalency	1993
Effects of an oral dose of isosorbide dinitrate on platelet function and fibrinolysis in healthy volunteers. British journal of clinical pharmacology, 1993, Volume: 35, Issue:2 Topics: Administration, Oral; Adult; beta-Thromboglobulin; Blood Platelets; Blood Pressure; Double-Blind Method; Epinephrine; Fibrinolysis; Heart Rate; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Platelet Aggregation; Vasodilation	1993
[Study of the bioequivalence of a new isosorbide dinitrate tablet formulation compared with the standard preparation]. Arzneimittel-Forschung, 1997, Volume: 47, Issue:6 Topics: Adult; Biological Availability; Cross-Over Studies; Female; Humans; Isosorbide Dinitrate; Male; Tablets; Therapeutic Equivalency; Vasodilator Agents	1997

Other Studies

57 other study(ies) available for isosorbide dinitrate and isosorbide-2-mononitrate

Article	Year
Effects of isosorbide-5-mononitrate and isosorbide-2-mononitrate on the contractile and electrical activity and on the content of cyclic nucleotides in isolated heart muscles of the guinea-pig and dog. The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:8 Topics: Animals; Cyclic AMP; Cyclic GMP; Dogs; Guinea Pigs; Heart; In Vitro Techniques; Isosorbide Dinitrate; Myocardial Contraction; Vasodilator Agents	1992
Pharmacokinetic/pharmacodynamic relationship of the duration of vasodilating action of organic mononitrates in rats. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2 Topics: Animals; Blood Pressure; Injections, Intravenous; Isosorbide Dinitrate; Male; Mathematics; Rats; Rats, Inbred Strains; Vasodilation	1992
Influence of standard and nicotine-reduced cigarette smoke on plasma concentrations of isosorbide dinitrate and its metabolites in rats. The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:11 Topics: Animals; Chromatography, Gas; Isosorbide Dinitrate; Male; Nicotine; Rats; Rats, Inbred Strains; Smoking	1991
Gas chromatographic analysis of isomeric organic mononitrates in plasma. Journal of chromatography, 1991, Nov-15, Volume: 571, Issue:1-2 Topics: Animals; Chromatography, Gas; Isomerism; Isosorbide Dinitrate; Nitrates; Rats	1991
Assay of glyceryl trinitrate, isosorbide dinitrate, and their metabolites in plasma by large-bore capillary column gas-liquid chromatography. Biopharmaceutics & drug disposition, 1990, Volume: 11, Issue:8 Topics: Chromatography, Gas; Humans; Isosorbide Dinitrate; Nitroglycerin	1990
Influence of emotional stress on pharmacokinetics of isosorbide dinitrate intraperitoneally administered to rats. Acta medica Okayama, 1990, Volume: 44, Issue:1 Topics: Animals; Electroshock; Foot; Injections, Intraperitoneal; Isosorbide Dinitrate; Male; Rats; Reference Values; Stress, Psychological	1990
Concentrations of isosorbide dinitrate, isosorbide-2-mononitrate and isosorbide-5-mononitrate in human vascular and muscle tissue under steady-state conditions. European journal of clinical pharmacology, 1990, Volume: 38, Issue:2 Topics: Aged; Chromatography, Gas; Humans; Isosorbide Dinitrate; Male; Middle Aged; Muscle, Smooth, Vascular; Muscles	1990
Mechanisms for the in vivo antiplatelet effects of isosorbide dinitrate. European heart journal, 1988, Volume: 9 Suppl A Topics: Adult; Epoprostenol; Female; Humans; Iloprost; In Vitro Techniques; Isosorbide Dinitrate; Male; Middle Aged; Platelet Aggregation Inhibitors; Thromboxane B2	1988
[Determination of isosorbide dinitrate and its degradation products in pharmaceuticals by gradient RP-HPLC]. Yao xue xue bao = Acta pharmaceutica Sinica, 1989, Volume: 24, Issue:10 Topics: Chromatography, High Pressure Liquid; Isosorbide Dinitrate	1989
Pharmacokinetics of isosorbide dinitrate, isosorbide-2-nitrate and isosorbide-5-nitrate in renal insufficiency after repeated oral dosage. Klinische Wochenschrift, 1989, Mar-15, Volume: 67, Issue:6 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Kidney Failure, Chronic; Kidney Function Tests; Male; Metabolic Clearance Rate; Middle Aged	1989
Influence of electric foot shock on pharmacokinetics of isosorbide dinitrate orally administered to rats. Japanese journal of pharmacology, 1989, Volume: 49, Issue:2 Topics: Administration, Oral; Animals; Electroshock; Isosorbide Dinitrate; Male; Rats; Rats, Inbred Strains; Stress, Psychological	1989
Determination of isosorbide dinitrate and its metabolites in plasma by gas chromatography on a capillary column with electron-capture detection. Journal of chromatography, 1989, Aug-25, Volume: 493, Issue:1 Topics: Chromatography, Gas; Humans; Isosorbide Dinitrate; Reference Standards	1989
Influence of electric foot shock on pharmacokinetics of isosorbide dinitrate subcutaneously administered to rats. Japanese journal of pharmacology, 1989, Volume: 51, Issue:1 Topics: Animals; Chromatography, Gas; Electroshock; Injections, Subcutaneous; Isosorbide Dinitrate; Male; Rats; Rats, Inbred Strains; Stress, Psychological; Temperature	1989
In vitro evidence of an endothelial cell-dependent antiplatelet activity for isosorbide dinitrate, but not for its 2- and 5-mononitrate metabolites. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Cell Extracts; Cells, Cultured; Dinoprostone; Endothelium; Female; Humans; Isosorbide Dinitrate; Male; Platelet Aggregation; Prostaglandins E; Thromboxane B2; Tissue Extracts	1987
Stimulation of coronary vascular PGI2 by organic nitrates. European heart journal, 1988, Volume: 9 Suppl A Topics: Animals; Cattle; Coronary Vessels; Epoprostenol; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Platelet Aggregation; Stereoisomerism; Structure-Activity Relationship; Sugar Alcohols; Thromboxane A2; Vasodilator Agents	1988
Influence of exercise on plasma concentrations of isosorbide dinitrate. European journal of clinical pharmacology, 1988, Volume: 35, Issue:2 Topics: Administration, Oral; Adult; Female; Humans; Isosorbide Dinitrate; Male; Physical Exertion; Rest	1988
Comparative pharmacokinetics of isosorbide nitrates after repeated doses of sustained release isosorbide dinitrate. Arzneimittel-Forschung, 1988, Volume: 38, Issue:9 Topics: Adult; Delayed-Action Preparations; Female; Half-Life; Humans; Isosorbide Dinitrate; Male; Tablets	1988
Organic nitrates: direct antiplatelet effects and synergism with prostacyclin. Antiplatelet effects of organic nitrates. Thrombosis and haemostasis, 1988, Apr-08, Volume: 59, Issue:2 Topics: Adult; Blood Platelets; Drug Synergism; Epoprostenol; Female; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Nitrates; Platelet Aggregation; Thromboxane B2	1988
Dose-dependent relaxation of human venous vessel strips with regard to chronic nitrate pretreatment. European heart journal, 1988, Volume: 9 Suppl A Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Humans; In Vitro Techniques; Isosorbide Dinitrate; Saphenous Vein; Vasodilation	1988
Control of the anti-thrombogenic endothelial cell defense by short- and long-term exposure of cultured endothelial cells to isosorbide nitrates. European heart journal, 1988, Volume: 9 Suppl A Topics: Animals; Cattle; Endothelium, Vascular; Humans; In Vitro Techniques; Isosorbide Dinitrate; Platelet Adhesiveness; Platelet Aggregation; Time Factors	1988
[Concentration-time profile of isosorbide dinitrate and its metabolites in plasma following percutaneous resorption of a transdermal therapeutic system]. Arzneimittel-Forschung, 1987, Volume: 37, Issue:11 Topics: Administration, Cutaneous; Adult; Biological Availability; Female; Humans; Isosorbide Dinitrate; Male; Time Factors	1987
Pharmacokinetics of isosorbide dinitrate and its mononitrate metabolites after intravenous infusion. Journal of pharmacokinetics and biopharmaceutics, 1986, Volume: 14, Issue:1 Topics: Adult; Aged; Female; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Kinetics; Male; Middle Aged; Models, Biological	1986
Characterization of vasodilators by comparison of their effects on blood pressure, counterregulation and myocardial oxygen demand in conscious normotensive dogs. Arzneimittel-Forschung, 1985, Volume: 35, Issue:1A Topics: Animals; Blood Pressure; Dihydralazine; Dogs; Female; Heart Rate; Isosorbide Dinitrate; Labetalol; Male; Molsidomine; Myocardium; Oxygen Consumption; Piperazines; Prazosin; Pyridazines; Renin; Sydnones; Vasodilator Agents	1985
[Delayed release forms of nitrates--are they obsolete today?]. Deutsche medizinische Wochenschrift (1946), 1985, Jan-18, Volume: 110, Issue:3 Topics: Coronary Disease; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Resistance; Humans; Isosorbide Dinitrate; Nitrates	1985
Pharmacokinetics and metabolism of isosorbide-dinitrate after intravenous and oral administration. European journal of clinical pharmacology, 1985, Volume: 27, Issue:6 Topics: Administration, Oral; Biological Availability; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Kinetics; Male; Models, Biological	1985
Isosorbide dinitrate bioavailability, kinetics, and metabolism. Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:2 Topics: Administration, Oral; Adult; Biological Availability; Humans; Injections, Intravenous; Isosorbide Dinitrate; Kinetics; Male; Models, Biological; Mouth Floor; Tablets	1985
Absorption and excretion of isosorbide dinitrate and isosorbide-2-mononitrate in dogs. The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:5 Topics: Absorption; Animals; Carbon Radioisotopes; Dogs; Half-Life; Isosorbide Dinitrate; Male	1983
Pharmacokinetics of nitroglycerin and long-acting nitrate esters. The American journal of medicine, 1983, Jun-27, Volume: 74, Issue:6B Topics: Absorption; Dose-Response Relationship, Drug; Humans; Isosorbide Dinitrate; Kinetics; Nitrates; Nitroglycerin	1983
Determination of the partitioning, stability, and metabolite formation of isosorbide dinitrate in human and rat blood using an improved gas-liquid chromatographic assay. Journal of chromatography, 1984, Jun-08, Volume: 308 Topics: Animals; Chromatography, Gas; Drug Stability; Humans; Isosorbide Dinitrate; Kinetics; Male; Nitroglycerin; Rats; Rats, Inbred Strains; Solubility	1984
Isosorbide 5-mononitrate and isosorbide 2-mononitrate kinetics after intravenous and oral dosing. Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:4 Topics: Absorption; Administration, Oral; Adult; Biological Availability; Female; Half-Life; Humans; Infusions, Parenteral; Injections, Intravenous; Isosorbide Dinitrate; Kinetics; Male	1984
Isosorbide dinitrate disposition in the rat: metabolite pharmacokinetics and interactions. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:1 Topics: Animals; Half-Life; Isosorbide Dinitrate; Kinetics; Male; Metabolic Clearance Rate; Rats; Rats, Inbred Strains	1984
Effect of 5-isosorbide mononitrate on isosorbide dinitrate-induced relaxation of rabbit aortic rings. Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:9 Topics: Animals; Aorta; Dose-Response Relationship, Drug; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle Relaxation; Rabbits; Vasodilation	1984
[Pharmacokinetics of isodinit (from Pharmachem) in humans]. Eksperimentalna meditsina i morfologiia, 1984, Volume: 23, Issue:3 Topics: Adult; Delayed-Action Preparations; Female; Humans; Isosorbide Dinitrate; Kinetics; Male; Middle Aged; Tablets	1984
Bioavailability of isosorbide dinitrate and its two mononitrate metabolites from sustained-release formulations. International journal of clinical pharmacology, therapy, and toxicology, 1983, Volume: 21, Issue:10 Topics: Adolescent; Adult; Biological Availability; Delayed-Action Preparations; Half-Life; Humans; Isosorbide Dinitrate; Male	1983
Single administration of atenolol does not influence the kinetics of orally given isosorbide dinitrate. International journal of clinical pharmacology research, 1983, Volume: 3, Issue:6 Topics: Administration, Oral; Adult; Aged; Atenolol; Humans; Isosorbide Dinitrate; Kinetics	1983
Oral absorption and disposition of isosorbide dinitrate and isosorbide mononitrates in man. Arzneimittel-Forschung, 1983, Volume: 33, Issue:7 Topics: Administration, Oral; Adult; Female; Humans; Intestinal Absorption; Isosorbide Dinitrate; Kinetics; Male; Middle Aged	1983
[Comparative antianginal, hemodynamic and pharmacokinetic effects of isosorbide-2-mononitrate and isosorbide dinitrate in the rat]. Arzneimittel-Forschung, 1983, Volume: 33, Issue:8 Topics: Angina Pectoris; Animals; Blood Pressure; Dihydroergotamine; Female; Hemodynamics; Isosorbide Dinitrate; Kinetics; Lypressin; Male; Rats; Rats, Inbred Strains; Species Specificity	1983
Determination of the two mononitrate metabolites of isosorbide dinitrate in human plasma and urine by gas chromatography with electron-capture detection. Journal of chromatography, 1984, Jan-13, Volume: 305, Issue:1 Topics: Chemical Phenomena; Chemistry; Chromatography, Gas; Humans; Hydrolysis; Isosorbide Dinitrate; Male; Time Factors	1984
Determination of isosorbide dinitrate and its mononitrate metabolites in human plasma using Extrelut purification and capillary column gas-liquid chromatography. Journal of chromatography, 1984, Mar-09, Volume: 306 Topics: Chromatography, Gas; Humans; Isosorbide Dinitrate; Kinetics	1984
Saliva concentrations of isosorbide dinitrate, isosorbide 2-mononitrate and isosorbide 5-mononitrate. British journal of clinical pharmacology, 1984, Volume: 17, Issue:5 Topics: Adult; Humans; Isosorbide Dinitrate; Male; Saliva	1984
[Isosorbide mononitrate or dinitrate in coronary disease?]. Deutsche medizinische Wochenschrift (1946), 1983, May-27, Volume: 108, Issue:21 Topics: Coronary Disease; Humans; Isosorbide Dinitrate	1983
[Hemodynamic effects of isosorbide-5-mononitrate in coronary heart disease. A comparison of acute and chronic treatment]. Deutsche medizinische Wochenschrift (1946), 1983, Sep-02, Volume: 108, Issue:35 Topics: Adult; Aged; Coronary Disease; Drug Evaluation; Electrocardiography; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Pulmonary Wedge Pressure; Time Factors	1983
Plasma concentrations of isosorbide dinitrate and mononitrates after acute and chronic oral administration of isosorbide dinitrate in man. Arzneimittel-Forschung, 1982, Volume: 32, Issue:7 Topics: Administration, Oral; Aged; Biotransformation; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Time Factors	1982
[Comparative pharmacokinetics and bioavailability of isosorbide dinitrate and its metabolites isosorbide 5- and 2-mononitrate from delayed-release preparations]. Arzneimittel-Forschung, 1982, Volume: 32, Issue:9 Topics: Adult; Biological Availability; Delayed-Action Preparations; Female; Humans; Isosorbide Dinitrate; Kinetics; Male	1982
[Hemodynamic effects of a transdermal formulation of isosorbide dinitrate and its pharmacokinetics in conscious dogs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 80, Issue:4 Topics: Administration, Topical; Animals; Delayed-Action Preparations; Dogs; Female; Hemodynamics; Isosorbide Dinitrate; Kinetics; Skin Absorption	1982
[Pharmacodynamics, pharmacokinetics and metabolism of isosorbide nitrates in the awake dog]. Die Medizinische Welt, 1981, Apr-07, Volume: 32, Issue:14A Topics: Animals; Dogs; Hemodynamics; Isosorbide; Isosorbide Dinitrate	1981
[Nitrite and methemoglobin formation in dogs following oral isosorbide dinitrate, isosorbide-2-mononitrate and isosorbide-5-mononitrate]. Die Medizinische Welt, 1981, Apr-07, Volume: 32, Issue:14A Topics: Animals; Dogs; Female; Isosorbide Dinitrate; Male; Methemoglobin; Nitrites	1981
Fate of isosorbide dinitrate and mononitrates in patients with renal failure. European journal of clinical pharmacology, 1981, Volume: 21, Issue:1 Topics: Adult; Aged; Female; Humans; Isosorbide Dinitrate; Kidney Diseases; Male; Middle Aged	1981
Inactivation of human aldehyde dehydrogenase by isosorbide dinitrate. The Journal of biological chemistry, 1994, Aug-26, Volume: 269, Issue:34 Topics: Aldehyde Dehydrogenase; Chloral Hydrate; Enzyme Reactivators; Esterases; Humans; Isoenzymes; Isosorbide Dinitrate; Mercaptoethanol; NAD; Oxidoreductases	1994
Pharmacokinetics of stereomeric 1,4:3,6-dianhydrohexitol mononitrates in rats. Pharmaceutical research, 1993, Volume: 10, Issue:1 Topics: Animals; Injections, Intravenous; Isosorbide Dinitrate; Male; Nitrates; Rats; Rats, Sprague-Dawley; Stereoisomerism; Sugar Alcohols; Vasodilator Agents	1993
[Plasma levels of isosorbide dinitrate and its metabolites during intravenous infusion in surgical patients--effect of preoperative administration of isosorbide dinitrate]. Masui. The Japanese journal of anesthesiology, 1993, Volume: 42, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Female; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Neuroleptanalgesia; Preanesthetic Medication; Surgical Procedures, Operative	1993
Isosorbide-2-mononitrate reduces the consequences of myocardial ischaemia, including arrhythmia severity: implications for preconditioning. Cardiovascular drugs and therapy, 2000, Volume: 14, Issue:5 Topics: Animals; Coronary Disease; Dogs; Female; Hemodynamics; Isosorbide Dinitrate; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Severity of Illness Index; Ventricular Fibrillation	2000
Effect of large volume injection of hydrophobic solvents on the retention of less hydrophobic pharmaceutical solutes in RP-LC. Journal of separation science, 2008, Volume: 31, Issue:16-17 Topics: Chromatography, Liquid; Heptanes; Hexanes; Hydrophobic and Hydrophilic Interactions; Isosorbide Dinitrate; Molecular Structure; Octanes; Parabens; Pentoxifylline; Sensitivity and Specificity; Solubility; Solvents; Tropicamide	2008
Differences between nitrates: role of isosorbide 2-mononitrate. Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:7 Topics: Animals; Aorta; Coronary Circulation; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Female; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle, Smooth, Vascular; Nitroglycerin; Perfusion; Rabbits; Vasodilation; Vasodilator Agents	2010
A simple and sensitive gas chromatography method for determination of isosorbide dinitrate and its metabolites in human plasma: application to pharmacokinetics study on oral spray. Drug research, 2014, Volume: 64, Issue:2 Topics: Administration, Oral; Adult; Drug Stability; Humans; Isosorbide Dinitrate; Male	2014
Radioprotective Properties of Indralin in Combination with Monizol in the Treatment of Local Acute and Delayed Radiation Injuries Caused by Local Skin γ-Irradiation. Bulletin of experimental biology and medicine, 2015, Volume: 159, Issue:6 Topics: Acute Disease; Administration, Oral; Animals; Drug Therapy, Combination; Female; Gamma Rays; Injections, Intraperitoneal; Isosorbide Dinitrate; Phenols; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Skin; Skin Diseases; Treatment Outcome	2015
Permeation-enhancing effects and mechanisms of O-acylterpineol on isosorbide dinitrate: mechanistic insights based on ATR-FTIR spectroscopy, molecular modeling, and CLSM images. Drug delivery, 2019, Volume: 26, Issue:1 Topics: Animals; Cells, Cultured; Drug Synergism; Humans; Isosorbide Dinitrate; Male; Microscopy, Confocal; Models, Molecular; Organ Culture Techniques; Permeability; Rabbits; Skin Absorption; Spectroscopy, Fourier Transform Infrared; Terpenes	2019