Page last updated: 2024-08-17

isosorbide dinitrate and arginine

isosorbide dinitrate has been researched along with arginine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (51.43)18.2507
2000's10 (28.57)29.6817
2010's7 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Allix, M; Boulu, R; Guillou, J; Plotkine, M1
de Graeff, PA; de Leeuw, MJ; Scholtens, E; van Gilst, WH; Wesseling, H1
Adams, ML; Cicero, TJ; Meyer, ER; Sewing, BN1
Capasso, F; Gaginella, TS; Izzo, AA; Mascolo, N2
Adams, ML; Chen, J; Cicero, TJ; Meyer, ER; Sewing, BN1
Gourine, AV1
Boustani, MR; Fanburg, BL; Hassoun, PM; Maloney, EK; White, AC1
Cui, LN; Inenaga, K; Nagatomo, T; Yamashita, H1
Göcer, F; Tuncer, M; Yaris, E1
Albino-Teixeira, A; Soares-da-Silva, P1
Autore, G; Barbato, F; Capasso, F; Izzo, AA; Mascolo, N1
Geppetti, P; Granger, H; Ledda, F; Masini, E; Morbidelli, L; Ziche, M1
Adams, ML; Cicero, TJ; Meyer, ER1
Avogadri, E; Camanni, F; Ghigo, E; Grottoli, S; Maccario, M; Oleandri, SE; Procopio, M1
Bortolotti, M; Brunelli, F; Miglioli, M; Sarti, P1
Endo, J; Ito, S; Kondo, Y; Nada, T; Nakaya, Y; Nomura, M; Saito, K; Yukinaka, M1
Kakishita, E; Suehiro, A; Yoshimoto, H1
Aono, T; Fukui, R; Hamada, Y; Kamada, M; Maeda, K; Nakaya, Y; Shimano, M1
Furuta, W; Kataoka, Y; Oishi, R; Sendo, T; Takeda, Y1
Brizzi, P; Maioli, M; Secchi, G; Severino, C; Solinas, A; Tonolo, G1
Aizawa, Y; Hori, T; Ishibashi, T; Kubota, K; Matsubara, T; Mezaki, T; Nakamura, Y; Nasuno, A; Nishio, M; Ozaki, K; Tanaka, T; Tsuchida, K; Yamazoe, M1
Barin, ES; Gilfillan, KL; Kaesemeyer, WH; Stokes, GS1
Czap, A1
Berti, F; Brini, AT; Clement, MG; De Gennaro Colonna, V; Manfredi, B; Polvani, G; Rossoni, G1
Chiossi, G; de Pace, V; Facchinetti, F1
Chakraborti, A; Gulati, K; Ray, A1
Kelm, M; Kleinbongard, P; Lauer, T; Rassaf, T; Rath, J; Schulz, R1
Chen, C; Dong, DL; Gao, LL; Hu, JT; Liang, J; Tu, YJ; Wang, ZG; Wu, JC; Yang, BF1
Li, H; Wang, S1
Cheng, FY; Lü, HX; Zhang, ZH; Zhou, JP1

Reviews

2 review(s) available for isosorbide dinitrate and arginine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clinical use of nitric oxide donors and L-arginine in obstetrics.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2007, Volume: 20, Issue:8

    Topics: Amniotic Fluid; Arginine; Biomarkers; Cervical Ripening; Female; Fetal Growth Retardation; Humans; Hypertension, Pregnancy-Induced; Isosorbide Dinitrate; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Obstetric Labor, Premature; Pregnancy; Uterine Contraction; Version, Fetal

2007

Trials

6 trial(s) available for isosorbide dinitrate and arginine

ArticleYear
Converting enzyme inhibitors and the role of the sulfhydryl group in the potentiation of exo- and endogenous nitrovasodilators.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:3

    Topics: Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Blood Pressure; Bradykinin; Captopril; Coronary Circulation; Cysteine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide; Nitro Compounds; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Vasodilator Agents

1991
Comparison among the effects of arginine, a nitric oxide precursor, isosorbide dinitrate and molsidomine, two nitric oxide donors, on hormonal secretions and blood pressure in man.
    Journal of endocrinological investigation, 1997, Volume: 20, Issue:8

    Topics: Adult; Arginine; Blood Glucose; Blood Pressure; Hormones; Humans; Isosorbide Dinitrate; Male; Molsidomine; Nitric Oxide; Vasodilator Agents

1997
Clinical and manometric effects of L-arginine in patients with chest pain and oesophageal motor disorders.
    Italian journal of gastroenterology and hepatology, 1997, Volume: 29, Issue:4

    Topics: Adult; Arginine; Chest Pain; Diagnosis, Differential; Double-Blind Method; Esophageal Motility Disorders; Female; Follow-Up Studies; Humans; Isosorbide Dinitrate; Male; Manometry; Middle Aged; Muscle Contraction; Muscle, Smooth; Vasodilator Agents

1997
Interactions of L-arginine, isosorbide mononitrate, and angiotensin II inhibitors on arterial pulse wave.
    American journal of hypertension, 2003, Volume: 16, Issue:9 Pt 1

    Topics: Aged; Aged, 80 and over; Angiotensin II; Arginine; Arteries; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Diastole; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide Donors; Posture; Pulse; Systole; Time Factors; Treatment Outcome; Vasoconstrictor Agents

2003
L-arginine preferentially dilates stenotic segments of coronary arteries thereby increasing coronary flow.
    Journal of internal medicine, 2008, Volume: 264, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Arginine; Blood Flow Velocity; Coronary Angiography; Coronary Circulation; Coronary Stenosis; Coronary Vessels; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Lipids; Male; Middle Aged; Vasodilation; Vasodilator Agents

2008
Organic nitrates favor regression of left ventricular hypertrophy in hypertensive patients on chronic peritoneal dialysis.
    International journal of molecular sciences, 2013, Jan-07, Volume: 14, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Arginine; Blood Pressure; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Isosorbide Dinitrate; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Prospective Studies; Time Factors; Treatment Outcome; Vasodilator Agents

2013

Other Studies

27 other study(ies) available for isosorbide dinitrate and arginine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
[Experimental antithrombotic activity of oral isosorbide dinitrate].
    Archives des maladies du coeur et des vaisseaux, 1992, Volume: 85 Spec No 1

    Topics: Administration, Oral; Animals; Arginine; Aspirin; Isosorbide Dinitrate; Male; NG-Nitroarginine Methyl Ester; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Research Design; Thrombosis

1992
Effects of nitric oxide-related agents on rat testicular function.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Drug Interactions; Hydralazine; Isosorbide Dinitrate; Male; NG-Nitroarginine Methyl Ester; Nicardipine; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Steroids; Stimulation, Chemical; Testis; Testosterone; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

1994
Nitric oxide as a mediator of the laxative action of magnesium sulphate.
    British journal of pharmacology, 1994, Volume: 113, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cathartics; Dexamethasone; Diarrhea; Gastrointestinal Transit; Isosorbide Dinitrate; Magnesium Sulfate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Water-Electrolyte Balance

1994
Nitric oxide-related agents alter alcohol withdrawal in male rats.
    Alcoholism, clinical and experimental research, 1995, Volume: 19, Issue:1

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Amino Acid Oxidoreductases; Animals; Arginine; Brain; Dose-Response Relationship, Drug; Isosorbide Dinitrate; Male; Neurologic Examination; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley

1995
Pharmacological evidence that nitric oxide can act as an endogenous antipyretic factor in endotoxin-induced fever in rabbits.
    General pharmacology, 1995, Volume: 26, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Body Temperature Regulation; Brain; Fever; Injections, Intraventricular; Isosorbide Dinitrate; Lipopolysaccharides; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits; Salmonella typhi

1995
Nitric oxide increases cellular glutathione levels in rat lung fibroblasts.
    American journal of respiratory cell and molecular biology, 1995, Volume: 13, Issue:4

    Topics: Animals; Arginine; Buthionine Sulfoximine; Cattle; Cell Line; Endothelium, Vascular; Enzyme Inhibitors; Fibroblasts; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Isosorbide Dinitrate; Lung; Methionine Sulfoximine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Pulmonary Artery; Rats; Vasodilator Agents

1995
Sodium nitroprusside modulates NMDA response in the rat supraoptic neurons in vitro.
    Brain research bulletin, 1994, Volume: 35, Issue:3

    Topics: Animals; Arginine; Cyclic GMP; Ferricyanides; In Vitro Techniques; Isosorbide Dinitrate; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurons; Nitroarginine; Nitroprusside; Protein Kinases; Quisqualic Acid; Rats; Rats, Wistar; Supraoptic Nucleus

1994
The action of amyl nitrite and isosorbide dinitrate on the contractility of sphincter of Oddi of guinea-pigs.
    General pharmacology, 1994, Volume: 25, Issue:5

    Topics: Acetylcholine; Amyl Nitrite; Animals; Arginine; Female; Guinea Pigs; In Vitro Techniques; Isosorbide Dinitrate; Male; Methylene Blue; Muscle Contraction; Nitric Oxide; omega-N-Methylarginine; Potassium Chloride; Sphincter of Oddi

1994
Dissociation of castor oil-induced diarrhoea and intestinal mucosal injury in rat: effect of NG-nitro-L-arginine methyl ester.
    British journal of pharmacology, 1994, Volume: 113, Issue:4

    Topics: Acid Phosphatase; Animals; Arginine; Castor Oil; Diarrhea; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Intestinal Mucosa; Isosorbide Dinitrate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Vasodilator Agents

1994
Isosorbide 5-mononitrate reverses high blood pressure in NG-nitro-L-arginine methyl ester treated rats.
    General pharmacology, 1994, Volume: 25, Issue:7

    Topics: Animals; Arginine; Blood Pressure; Brain; Dopamine; Drinking; Drug Interactions; Epinephrine; Heart Rate; Hypertension; Isosorbide Dinitrate; Male; Methoxyhydroxyphenylglycol; NG-Nitroarginine Methyl Ester; Norepinephrine; Rats; Rats, Wistar; Sympathetic Nervous System; Tissue Distribution; Vasodilator Agents

1994
Nitric oxide and castor oil-induced diarrhea.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1

    Topics: Animals; Arginine; Body Fluids; Castor Oil; Diarrhea; Electrolytes; Gastrointestinal Motility; Intestine, Small; Isosorbide Dinitrate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar

1994
Nitric oxide promotes DNA synthesis and cyclic GMP formation in endothelial cells from postcapillary venules.
    Biochemical and biophysical research communications, 1993, May-14, Volume: 192, Issue:3

    Topics: Animals; Arginine; Cattle; Cells, Cultured; Coronary Vessels; Cyclic GMP; DNA; DNA Replication; Endothelium, Vascular; Fibroblast Growth Factor 2; Isosorbide Dinitrate; Kinetics; Nitric Oxide; Nitroglycerin; Nitroprusside; omega-N-Methylarginine; Thymidine; Venules

1993
Effects of nitric oxide-related agents on opioid regulation of rat testicular steroidogenesis.
    Biology of reproduction, 1996, Volume: 54, Issue:5

    Topics: Animals; Arginine; Chorionic Gonadotropin; Enzyme Inhibitors; Isosorbide Dinitrate; Male; Morphine; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Testis; Testosterone

1996
Effects of intravenous administration of L-arginine on autonomic nervous activities. Analysis of heart rate variability.
    Japanese heart journal, 1998, Volume: 39, Issue:3

    Topics: Adult; Arginine; Autonomic Nervous System; Biomarkers; Blood Pressure; Electrocardiography, Ambulatory; Heart Rate; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Reference Values; Time Factors; Vasodilator Agents

1998
Exogenous nitric oxide inhibits platelet activation in whole blood.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:1

    Topics: Arginine; Blood Coagulation; Blood Platelets; Collagen; Cyclic GMP; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitric Oxide; Nitroprusside; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Vasodilator Agents; Whole Blood Coagulation Time

1999
Activation of Ca2+-activated K+ channels in human myometrium by nitric oxide.
    Gynecologic and obstetric investigation, 2000, Volume: 49, Issue:4

    Topics: Arginine; Calcium; Electric Conductivity; Enzyme Inhibitors; Female; Humans; Isosorbide Dinitrate; Lipopolysaccharides; Myometrium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Potassium Channels; Pregnancy

2000
Nitric oxide protects against contrast media-increased pulmonary vascular permeability in rats.
    Investigative radiology, 2000, Volume: 35, Issue:8

    Topics: Animals; Arginine; Capillary Permeability; Contrast Media; Enzyme Inhibitors; Injections, Intravenous; Iohexol; Ioxaglic Acid; Isosorbide Dinitrate; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Vasodilator Agents

2000
Low-dose dexamethasone in the rat: a model to study insulin resistance.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 283, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Dexamethasone; Dose-Response Relationship, Drug; Drug Combinations; Glucocorticoids; Hypertension; Hypoglycemic Agents; Injections, Subcutaneous; Insulin Resistance; Isosorbide Dinitrate; Male; Metformin; Rats; Rats, Wistar

2002
Significance of asymmetric dimethylarginine (ADMA) concentrations during coronary circulation in patients with vasospastic angina.
    Circulation journal : official journal of the Japanese Circulation Society, 2003, Volume: 67, Issue:4

    Topics: Aged; Angina Pectoris; Arginine; Case-Control Studies; Coronary Angiography; Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Enzyme Inhibitors; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitrites; Osmolar Concentration; Risk Factors; Vasodilator Agents; Vasomotor System

2003
Color blind, or just plain blind?
    Alternative medicine review : a journal of clinical therapeutic, 2005, Volume: 10, Issue:2

    Topics: Arginine; Black People; Delayed-Action Preparations; Drug Combinations; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Nitric Oxide; Pharmacogenetics; Vasodilator Agents

2005
Nitric oxide and prostacyclin pathways: an integrated mechanism that limits myocardial infarction progression in anaesthetized rats.
    Pharmacological research, 2006, Volume: 53, Issue:4

    Topics: Animals; Arginine; Arrhythmias, Cardiac; Cardiotonic Agents; Creatine Kinase; Epoprostenol; Isosorbide Dinitrate; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Naproxen; Nitric Oxide; Peroxidase; Polydeoxyribonucleotides; Random Allocation; Rats; Rats, Wistar; Thromboxane B2

2006
Modulation of stress-induced neurobehavioral changes and brain oxidative injury by nitric oxide (NO) mimetics in rats.
    Behavioural brain research, 2007, Nov-02, Volume: 183, Issue:2

    Topics: Animals; Arginine; Behavior, Animal; Brain; Glutathione; Isosorbide Dinitrate; Lipid Peroxidation; Male; Maze Learning; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; Stress, Psychological

2007
Effects of isosorbide mononitrate on the restoration of injured artery in mice in vivo.
    European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3

    Topics: Animals; Arginine; Carotid Artery Injuries; Electric Stimulation; Endothelial Cells; Isosorbide Dinitrate; Mice

2010
[The effects and its mechanism of N-arginine chitosan as transdermal enhancer].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:8

    Topics: Administration, Cutaneous; Animals; Arginine; Aspirin; Cell Line; Cell Survival; Cell-Penetrating Peptides; Chitosan; Drug Carriers; Humans; Isosorbide Dinitrate; Keratinocytes; Male; Mice; Prazosin; Skin Absorption

2013