isosorbide dinitrate has been researched along with acetylcysteine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 7 (33.33) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Blaschke, TF; Hoffman, BB; Kongpatanakul, S; Vincent, J | 1 |
| Auclert, L; Blin, P; Guérin, C; Guérin, F; Pellois, A; Touiza, K; Weber, S | 1 |
| Aldershvile, J; Boesgaard, S; Grande, P; Madsen, JK; Pedersen, F; Pietersen, A | 1 |
| Aldershvile, J; Boesgaard, S; Poulsen, HE | 1 |
| Holzmann, S; Kukovetz, WR | 1 |
| Aldershvile, J; Klarlund, K; Svendsen, JH; Waldorff, S | 1 |
| Hawlicek, J; Kalenbach, M; Kirsten, N; Kober, G; Krause, A; Satter, P; Schneider, W; von Loh, D; Weyenmeyer, T | 1 |
| Ohba, Y; Sakai, K; Shiraki, Y | 1 |
| Flaherty, JT | 1 |
| Farrell, B; Lahey, KA; Parker, JO; Rose, BF | 1 |
| Elkayam, U; Hsueh, W; Mehra, A; Ostrzega, E; Shotan, A; Vasquez-Johnson, J | 1 |
| Mollace, V; Pistelli, A; Salvemini, D | 1 |
| Aldershvile, J; Boesgaard, S; Christensen, S; Dige-Petersen, H; Giese, J; Poulsen, HE | 1 |
| Nosalova, G; Strapkova, A | 1 |
| Bai, A; Calvillo, L; De Angelis, N; Fiordaliso, F; Ghezzi, P; Latini, R; Masson, S; Pollicino, L; Salio, M; Santangelo, F | 1 |
| Borodulin, RR; Burgova, EN; Mikoyan, VD; Vanin, AF | 1 |
2 review(s) available for isosorbide dinitrate and acetylcysteine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Evaluation of tolerance during intravenous administration of low dose of isosorbide dinitrate in the treatment of unstable angina].
Topics: Acetylcysteine; Adult; Aged; Angina, Unstable; Blood Pressure; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Tachyphylaxis | 1992 |
7 trial(s) available for isosorbide dinitrate and acetylcysteine
| Article | Year |
|---|---|
[Evaluation of tolerance during intravenous administration of low dose of isosorbide dinitrate in the treatment of unstable angina].
Topics: Acetylcysteine; Adult; Aged; Angina, Unstable; Blood Pressure; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Tachyphylaxis | 1992 |
Continuous oral N-acetylcysteine treatment and development of nitrate tolerance in patients with stable angina pectoris.
Topics: Acetylcysteine; Administration, Oral; Aged; Angina Pectoris; Double-Blind Method; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Time Factors | 1991 |
Preventive administration of intravenous N-acetylcysteine and development of tolerance to isosorbide dinitrate in patients with angina pectoris.
Topics: Acetylcysteine; Adult; Aged; Angina Pectoris; Double-Blind Method; Drug Combinations; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Injections, Intravenous; Isosorbide Dinitrate; Middle Aged; Rest | 1992 |
N-acetylcysteine modifies the acute effects of isosorbide-5-mononitrate in angina pectoris patients evaluated by exercise testing.
Topics: Acetylcysteine; Administration, Sublingual; Adult; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Random Allocation | 1989 |
Nitrate tolerance: the lack of effect of N-acetylcysteine.
Topics: Acetylcysteine; Administration, Oral; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Nitrates; Random Allocation; Time Factors | 1987 |
Potentiation of isosorbide dinitrate effects with N-acetylcysteine in patients with chronic heart failure.
Topics: Acetylcysteine; Adult; Aged; Atrial Natriuretic Factor; Catecholamines; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Female; Heart Failure; Humans; Isosorbide Dinitrate; Male; Middle Aged; Renin | 1994 |
N-acetylcysteine inhibits angiotensin converting enzyme in vivo.
Topics: Acetylcysteine; Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Drug Interactions; Female; Heart Rate; Humans; Isosorbide Dinitrate; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin | 1993 |
13 other study(ies) available for isosorbide dinitrate and acetylcysteine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Desensitization of nitrate-induced venodilation: reversal with oral N-acetylcysteine in humans.
Topics: Acetylcysteine; Adult; Blood Pressure Determination; Dose-Response Relationship, Drug; Drug Tolerance; Female; Hand; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Regional Blood Flow; Vasodilation | 1992 |
Cyclic GMP in nicorandil-induced vasodilatation and tolerance development.
Topics: Acetylcysteine; Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Vasodilation; Vasodilator Agents | 1987 |
[Isolated human venous segments as a model for the study of problems of nitrate tolerance].
Topics: Acetylcysteine; Coronary Artery Bypass; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Isosorbide Dinitrate; Muscle, Smooth, Vascular; Nitroglycerin; Saphenous Vein; Vascular Resistance; Vasodilation | 1989 |
Comparative vasorelaxing profiles of nicorandil, isosorbide dinitrate and nitroglycerin in isolated coronary arteries of the dog.
Topics: Acetylcysteine; Animals; Coronary Vessels; Dinoprost; Dogs; Endothelium; Female; In Vitro Techniques; Isosorbide Dinitrate; Male; Methylene Blue; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Chloride; Prostaglandins F; Vasodilator Agents | 1987 |
Hemodynamic attenuation and the nitrate-free interval: alternative dosing strategies for transdermal nitroglycerin.
Topics: Acetylcysteine; Administration, Oral; Administration, Topical; Angina Pectoris; Angina, Unstable; Animals; Blood Vessels; Cheek; Cyclic GMP; Drug Administration Schedule; Drug Tolerance; Electrocardiography; Endothelium; Exercise Test; Hemodynamics; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Nitroglycerin; Prostaglandins; Vascular Resistance | 1985 |
Release of nitric oxide from glyceryl trinitrate by captopril but not enalaprilat: in vitro and in vivo studies.
Topics: Acetylcysteine; Animals; Captopril; Cattle; Enalapril; Endothelium, Vascular; Glutathione; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitroglycerin; Platelet Aggregation; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
Nitric oxide and airway reactivity.
Topics: Acetylcysteine; Administration, Inhalation; Animals; Guinea Pigs; Histamine; In Vitro Techniques; Isosorbide Dinitrate; Lung; Male; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Donors; Toluene; Trachea | 2001 |
In vivo cardioprotection by N-acetylcysteine and isosorbide 5-mononitrate in a rat model of ischemia-reperfusion.
Topics: Acetylcysteine; Animals; Blood Pressure; Drug Therapy, Combination; Free Radical Scavengers; Isosorbide Dinitrate; Male; Monocytes; Myocardial Infarction; Myocardial Reperfusion Injury; Neutrophils; Nitric Oxide Donors; Rats; Rats, Sprague-Dawley | 2003 |
The binuclear form of dinitrosyl iron complexes with thiol-containing ligands in animal tissues.
Topics: Acetylcysteine; Animals; Ditiocarb; Ferrous Compounds; Glutathione; Hemoglobins; Isosorbide Dinitrate; Ligands; Lipopolysaccharides; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; S-Nitrosoglutathione; Sorbitol; Spin Labels; Thiocarbamates | 2017 |