isoproterenol has been researched along with wortmannin in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (32.14) | 18.2507 |
| 2000's | 17 (60.71) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Hazeki, O; Kawano, Y; Okada, T; Sakakibara, T; Ui, M | 1 |
| Avison, MB; Denton, RM; Diggle, TA; Flynn, A; Foulstone, EJ; Moule, SK; Proud, CG | 1 |
| Burnett, P; Denton, RM; Diggle, TA; Edgell, NJ; McCormack, JG; Moule, SK; Rutter, GA | 1 |
| Denton, RM; Edgell, NJ; Foulstone, EJ; Moule, SK; Proud, CG; Welsh, GI | 1 |
| bin He, Z; Elberg, G; Li, J; Sekar, N; Shechter, Y | 1 |
| Fürnsinn, C; Herdlicka, R; Leighton, B; Noe, C; Nowotny, P; Roden, M; Waldhäusl, W | 1 |
| Ahmad, F; Belfrage, P; Degerman, E; Holst, LS; Landström, TR; Manganiello, V; Wijkander, J | 1 |
| Goldberg, Y; Piper, HM; Schlüter, KD; Taimor, G | 1 |
| Goldberg, Y; Piper, HM; Schäfer, M; Schlüter, KD; Taimor, G | 1 |
| Hattori, R; Imamura, H; Kawaguchi, H; Nakao, Y; Osako, M; Otani, H; Yamamura, T | 1 |
| Claes, P; Grobben, B; Roymans, D; Slegers, H | 1 |
| Hashimoto, K; Hori, M; Imahashi, K; Kusuoka, H; Nishimura, T; Terakawa, T; Yoshioka, J | 1 |
| Greenberg, AG; Kraemer, FB; Xue, B; Zemel, MB | 1 |
| Gosmanov, AR; Thomason, DB | 1 |
| Bard, M; Diglio, CA; Isenović, E; Muniyappa, R; Sowers, JR; Walsh, MF | 1 |
| Biazzo-Ashnault, DE; Ding, VD; Jones, AB; Li, Z; Liu, K; Moller, DE; Qureshi, SA; Szalkowski, D; Xie, D; Zhang, BB | 1 |
| Eckhart, AD; Eguchi, S; Kim, J; Koch, WJ | 1 |
| Carpéné, C; Marti, L; Prévot, D; Visentin, V | 1 |
| Slomiany, A; Slomiany, BL | 1 |
| Coash, M; Ferro, A; Ji, Y; Queen, L; Rob, J; Yamamoto, T | 1 |
| Chakir, K; Crow, MT; Jo, SH; Lakatta, EG; Leblais, V; Maltsev, V; Wang, W; Xiao, RP; Zheng, M | 1 |
| Bengtsson, T; Hutchinson, DS; Yamamoto, DL | 1 |
| Grundke-Iqbal, I; Iqbal, K; Sengupta, A | 1 |
| Chen, K; Cong, L; Gao, P; Li, J; Li, Q; Mi, S; Wu, X; Zhao, AZ | 1 |
| Alloatti, G; Boero, O; Brero, A; Gallo, MP; Levi, R; Ramella, R; Tota, B | 1 |
| Goupil, E; Hébert, TE; Laporte, SA; Wrzal, PK; Zingg, HH | 1 |
| Datusalia, AK; Deep, A; Kumar, A; Nagaich, U; Rajput, SK; Sharma, AK; Taneja, G | 1 |
28 other study(ies) available for isoproterenol and wortmannin
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin.
Topics: Adipocytes; Androstadienes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Cytosol; Deoxyglucose; Glucose; Hydrogen Peroxide; Insulin; Isoproterenol; Kinetics; Lipolysis; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Rats; Wortmannin | 1994 |
Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in response to insulin in rat epididymal fat-cells.
Topics: Adipocytes; Androstadienes; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Enzyme Inhibitors; Epidermal Growth Factor; Epididymis; Eukaryotic Initiation Factor-4E; Insulin; Intracellular Signaling Peptides and Proteins; Isoproterenol; Kinetics; Male; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Polyenes; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases; Sirolimus; Wortmannin | 1996 |
The hormonal regulation of pyruvate dehydrogenase complex.
Topics: Acetyl-CoA Carboxylase; Adipocytes; Androstadienes; Animals; Calcium; Energy Metabolism; Epinephrine; Hormones; Insulin; Isoproterenol; Lipid Metabolism; Mitochondria; Myocardium; Permeability; Phosphorylation; Polyenes; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Complex; Rats; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Wortmannin | 1996 |
Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms.
Topics: Adipocytes; Adrenergic beta-Agonists; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epididymis; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Insulin; Isoproterenol; Male; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Polyenes; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Sirolimus; Wortmannin | 1997 |
Antilipolytic actions of vanadate and insulin in rat adipocytes mediated by distinctly different mechanisms.
Topics: Adipocytes; Adipose Tissue; Androstadienes; Animals; Bucladesine; Catecholamines; Cells, Cultured; Epididymis; Insulin; Isoproterenol; Kinetics; Lipolysis; Male; Molybdenum; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Tungsten Compounds; Vanadates; Wortmannin | 1997 |
More marked stimulation by lithium than insulin of the glycogenic pathway in rat skeletal muscle.
Topics: Androstadienes; Animals; Biological Transport; Cytochalasin B; Dantrolene; Deoxyglucose; Glucose; Glycogen; Glycogen Synthase; In Vitro Techniques; Insulin; Insulin-Like Growth Factor I; Isoproterenol; Kinetics; Lactates; Lithium Chloride; Male; Muscle, Skeletal; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Wortmannin | 1997 |
Phosphorylation and activation of hormone-sensitive adipocyte phosphodiesterase type 3B.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipocytes; Androstadienes; Animals; Consensus Sequence; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Enzyme Activation; Hormones; Insulin; Isoproterenol; Metalloendopeptidases; Phosphodiesterase Inhibitors; Phosphopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Trypsin; Wortmannin | 1998 |
Intracellular signaling leads to the hypertrophic effect of neuropeptide Y.
Topics: Androstadienes; Animals; Aprotinin; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cells, Cultured; Creatine Kinase; Cyclic AMP; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; GTP-Binding Proteins; Heart; Heart Ventricles; Isoenzymes; Isoproterenol; Male; Models, Cardiovascular; Myocardium; Neuropeptide Y; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Wortmannin | 1998 |
Role of phosphatidylinositol 3-kinase activation in the hypertrophic growth of adult ventricular cardiomyocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Androstadienes; Animals; Cardiomegaly; Cells, Cultured; Chromatography, Thin Layer; Chromones; DNA; Enzyme Activation; Enzyme Inhibitors; Isoproterenol; Male; Morpholines; Myocardium; Phenylalanine; Phenylephrine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Biosynthesis; Rats; Rats, Wistar; RNA; Signal Transduction; Stimulation, Chemical; Time Factors; Uridine; Wortmannin | 1998 |
Insulin-like growth factor-I improves recovery of cardiac performance during reperfusion in isolated rat heart by a wortmannin-sensitive mechanism.
Topics: Androstadienes; Animals; Creatine Kinase; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Heart Ventricles; In Vitro Techniques; Insulin-Like Growth Factor I; Isoproterenol; Male; Muscle Contraction; Myocardial Contraction; Oxygen Consumption; Perfusion; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Wortmannin | 2000 |
Protein tyrosine kinase-dependent regulation of adenylate cyclase and phosphatidylinositol 3-kinase activates the expression of glial fibrillary acidic protein upon induction of differentiation in rat c6 glioma.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Androstadienes; Animals; Anti-Bacterial Agents; Benzoquinones; Cell Differentiation; Chromones; Cyclic AMP; Enzyme Inhibitors; Flavonoids; Gene Expression; Glial Fibrillary Acidic Protein; Glioma; Indoles; Isoproterenol; Isoquinolines; Lactams, Macrocyclic; Maleimides; Morpholines; Phosphatidylinositol 3-Kinases; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Sirolimus; Sulfonamides; Tumor Cells, Cultured; Wortmannin | 2001 |
Troglitazone enhances glucose uptake induced by alpha-adrenoceptor stimulation via phosphatidylinositol 3-kinase in rat heart.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Androstadienes; Animals; Catecholamines; Chromans; Glucose; Heart; Hemodynamics; Humans; In Vitro Techniques; Insulin; Isoproterenol; Male; Myocardium; Phentolamine; Phenylephrine; Phosphates; Phosphatidylinositol 3-Kinases; Phosphocreatine; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sugar Phosphates; Thiazoles; Thiazolidinediones; Time Factors; Troglitazone; Wortmannin | 2001 |
Mechanism of intracellular calcium ([Ca2+]i) inhibition of lipolysis in human adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Androstadienes; Bucladesine; Calcium; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Humans; Insulin; Isoproterenol; Lipolysis; Phosphodiesterase Inhibitors; Phosphorylation; Potassium Chloride; Quinolones; Sterol Esterase; Wortmannin; Xanthines | 2001 |
Insulin and isoproterenol differentially regulate mitogen-activated protein kinase-dependent Na(+)-K(+)-2Cl(-) cotransporter activity in skeletal muscle.
Topics: Androstadienes; Animals; Chromones; Female; Imidazoles; Insulin; Isoproterenol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Potassium; Pyridines; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters; Wortmannin | 2002 |
Phosphatidylinositol 3-kinase may mediate isoproterenol-induced vascular relaxation in part through nitric oxide production.
Topics: Adrenergic beta-Agonists; Androstadienes; Animals; Aorta; Cells, Cultured; Chromones; Cytoskeleton; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Male; Morpholines; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Wortmannin | 2002 |
Regulation of insulin signal transduction pathway by a small-molecule insulin receptor activator.
Topics: Adipocytes; Androstadienes; Animals; Blotting, Western; CHO Cells; Cricetinae; Enzyme Inhibitors; Glucose; Glycerol; Glycogen Synthase; Humans; Insulin; Isoproterenol; Male; Phosphorylation; Rats; Rats, Wistar; Receptor, Insulin; Ribosomal Protein S6 Kinases; Signal Transduction; Wortmannin | 2002 |
Beta-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases.
Topics: Androstadienes; Animals; Cells, Cultured; DNA Replication; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Fibroblasts; Heart; Isoproterenol; Male; Mitogen-Activated Protein Kinases; Myocardium; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tyrphostins; Virulence Factors, Bordetella; Wortmannin | 2002 |
Inhibition of rat fat cell lipolysis by monoamine oxidase and semicarbazide-sensitive amine oxidase substrates.
Topics: Adipocytes; Amine Oxidase (Copper-Containing); Androstadienes; Animals; Benzylamines; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glutathione; Hydrogen Peroxide; Insulin; Isoproterenol; Lipolysis; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxidation-Reduction; Pargyline; Phosphoinositide-3 Kinase Inhibitors; Quercetin; Rats; Rats, Wistar; Substrate Specificity; Tyramine; Vanadates; Wortmannin | 2003 |
Salivary phospholipid secretion in response to beta-adrenergic stimulation is mediated by Src kinase-dependent epidermal growth factor receptor transactivation.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Androstadienes; Animals; Bucladesine; Choline; Colforsin; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Isoproterenol; Phosphoinositide-3 Kinase Inhibitors; Phospholipids; Pyrimidines; Quinazolines; Rats; Receptors, Adrenergic, beta; Saliva; src-Family Kinases; Sublingual Gland; Transcriptional Activation; Wortmannin | 2004 |
Nitric oxide-dependent beta2-adrenergic dilatation of rat aorta is mediated through activation of both protein kinase A and Akt.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Androstadienes; Animals; Aorta, Thoracic; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Propanolamines; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Sulfonamides; Vasodilation; Wortmannin | 2004 |
Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyocytes.
Topics: Androstadienes; Animals; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Chromones; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Insulin-Like Growth Factor I; Ion Transport; Isoproterenol; Morpholines; Myocardial Contraction; Myocytes, Cardiac; Norepinephrine; Patch-Clamp Techniques; Peptide Fragments; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prazosin; Propanolamines; Protein Processing, Post-Translational; Rats; Receptors, Adrenergic, beta-1; Recombinant Proteins; Second Messenger Systems; Signal Transduction; Wortmannin | 2004 |
Beta(2)-Adrenergic activation increases glycogen synthesis in L6 skeletal muscle cells through a signalling pathway independent of cyclic AMP.
Topics: Adrenergic beta-Agonists; AMP-Activated Protein Kinases; Androstadienes; Animals; Cell Line; Cyclic AMP; Glucose; Glycogen; Glycogen Synthase Kinase 3; Insulin; Isoproterenol; Multienzyme Complexes; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; Receptors, Adrenergic, beta-2; Signal Transduction; Wortmannin | 2007 |
Regulation of phosphorylation of tau by protein kinases in rat brain.
Topics: Alzheimer Disease; Androstadienes; Animals; Blotting, Western; Bradykinin; Brain Chemistry; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclin-Dependent Kinase 5; Enzyme Activators; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; In Vitro Techniques; Isoproterenol; Male; Microtubules; Phosphorylation; Protein Kinases; Rats; tau Proteins; Wortmannin | 2006 |
Regulation of adiponectin and leptin secretion and expression by insulin through a PI3K-PDE3B dependent mechanism in rat primary adipocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Adiponectin; Adrenergic beta-Agonists; Androstadienes; Animals; Chromones; Cyclic Nucleotide Phosphodiesterases, Type 3; Insulin; Isoproterenol; Leptin; Male; Milrinone; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Wortmannin | 2007 |
Endothelium-derived nitric oxide mediates the antiadrenergic effect of human vasostatin-1 in rat ventricular myocardium.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Androstadienes; Animals; Calcium Channels, L-Type; Calcium Signaling; Cattle; Cells, Cultured; Chromogranin A; Dose-Response Relationship, Drug; Endothelial Cells; Female; Heart Ventricles; Humans; In Vitro Techniques; Isoproterenol; Muscle Strength; Myocardial Contraction; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Papillary Muscles; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Rats; Recombinant Proteins; Wortmannin | 2007 |
Functional interactions between the oxytocin receptor and the β2-adrenergic receptor: implications for ERK1/2 activation in human myometrial cells.
Topics: Adrenergic beta-2 Receptor Agonists; Androstadienes; Carbazoles; Cell Line; Enzyme Activation; ErbB Receptors; Female; Gene Expression; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Indoles; Isoproterenol; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myometrium; Oxytocin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Binding; Protein Kinase C; Receptors, Adrenergic, beta-2; Receptors, Oxytocin; Recombinant Proteins; Wortmannin | 2012 |
Combined and individual strategy of exercise generated preconditioning and low dose copper nanoparticles serve as superlative approach to ameliorate ISO-induced myocardial infarction in rats.
Topics: Androstadienes; Animals; Cardiotonic Agents; Copper; Creatine Kinase, MB Form; Glycogen Synthase Kinase 3 beta; Ischemic Preconditioning, Myocardial; Isoproterenol; L-Lactate Dehydrogenase; Lipids; Male; Myocardial Infarction; Nanoparticles; Nitrates; Nitrites; Oxidative Stress; Phosphorylation; Physical Conditioning, Animal; Proto-Oncogene Proteins c-akt; Rats; Thiobarbituric Acid Reactive Substances; Troponin I; Wortmannin | 2018 |