isoproterenol and timolol

isoproterenol has been researched along with timolol in 119 studies

Research

Studies (119)

Timeframe	Studies, this research(%)	All Research%
pre-1990	61 (51.26)	18.7374
1990's	36 (30.25)	18.2507
2000's	14 (11.76)	29.6817
2010's	8 (6.72)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Le Douarec, JC; Plazonnet, B; Sears, ML; Silverstone, D; Stone, CA; Vareilles, P	1
Julius, S; Kiowski, W; Simon, G	1
Dickerson, DD; Fulmor, IE; Goldberg, ME; Lee, RJ	1
Nencini, P	1
Neufeld, AH; Page, ED	1
Davies, RJ; Davy, CR; Greenacre, JK; Reed, M; Turner, P	1
Candia, OA; Neufeld, AH; Podos, SM	1
Leopold, IH; Murray, DL	1
Cheymol, G; Heckle, J; Jaillon, P; Weissenburger, J	1
Graham, RM; Oates, HF; Stoker, LM; Stokes, GS	1
Chandler, MH; Clifton, GD; Harrison, MR; McCoy, RA; Pennell, AT	1
Christoffersen, T; Dajani, L; Dajani, OF; Refsnes, M; Sandnes, D; Thoresen, GH	1
Challiss, RA; Morgan, AJ; Murray, KJ	1
Järvinen, K; Urtti, A	1
Moudy, AM; Schwartzkroin, PA	1
Leon, M; McGaugh, JL; Sullivan, RM	1
Armour, JA; Boudreau, G; Cardinal, R; Watson-Wright, W	1
Patil, PN; Weber, PA	1
Havula, P; Huupponen, R; Iisalo, E; Kaila, T; Karhuvaara, S; Salminen, L; Scheinin, M	1
Beusenberg, FD; Bonta, IL; Leurs, R; van Amsterdam, JG; van Schaik, A	1
Kemken, J; Müller, BW; Ziegler, A	1
Hugues, FC; Le Jeunne, C; Munera, Y	1
Kiuchi, Y	1
Siegl, PK; Wenger, HC	1
Deisher, TA; Hoffman, BB; Mankani, S	1
Barradas, MA; Dandona, P; Khokher, MA; Mikhailidis, DP; Turaihi, K	1
Nathanson, JA	4
Palkama, A; Raij, K; Uusitalo, H; Uusitalo, R	1
Wilkinson, DA; Wilkinson, M	1
Richards, R; Tattersfield, AE	1
Chen, J; Padillo, E; Ruiz, G; Woodward, DF	1
Keshmirian, J; Nogrady, T	1
Berlin, I; Le Hoang, P; Marcel, P; Millon, D; Puech, AJ; Uzzan, B	1
Chen, J; Dowling, MC; Feldmann, BJ; Woodward, DF	1
Hugues, FC; Le Jeunne, C; Munera, Y; Teillet, L	1
Bundgaard, H; Lee, VH; Potter, DE; Shumate, DJ	1
Cherian, L; Klemm, WR; Sukul, NC	1
Lu, DY	1
Gilmartin, B; Hogan, RE	1
Nielsen, CB; Nielsen, PJ	1
Bromberger-Barnea, B; Menkes, HA; Spannhake, EW; Weinmann, GG	1
Gal, J; Gerber, JG; Klein, C; Nies, AS	1
Nagasubramanian, S; Poinoosawmy, D	1
Bartels, SP; Brandt, JD; Neufeld, AH	1
Kodama, T; Macri, FJ; Reddy, VN	1
Hopkins, WF; Johnston, D	1
Potter, DE; Rowland, JM	1
Bartels, SP; Jumblatt, MM; Neufeld, AH; Roth, HO	1
Arison, BH; Ellsworth, RL; Hall, RA; Hensens, OD; Rooney, CS; Scheigetz, J; Share, NN; Tocco, DJ; VandenHeuvel, WJ; Wasson, BK	1
Hedges, A; Kilfeather, S; Lima, DR; Turner, P	1
Lefer, AM; Lefer, DJ; Levin, RJ	1
Baer, M; Chanton, C; Porzig, H	1
Cerino, D; Kling, P; Lotti, VJ	2
Jumblatt, MM; Neufeld, AH	1
Teräväinen, H	1
Bromberg, BB; Gregory, DS; Sears, ML	1
Dunwiddie, TV; Hoffer, BJ; Mueller, AL	1
ten Ham, M; van Bijsterveld, OP; van Loenen, AC	1
McNeill, JH; Siegl, PK	1
MacLeod, KM; McNeill, JH; Rodgers, RL; Siegl, PK	1
Churchill, MC; Churchill, PC; McDonald, FD	1
Borkowski, KR; Porter, M	1
Bausher, L; Caprioli, J; Gregory, D; Mead, A; Sears, M	1
Coltart, J; Crome, R; Hearse, D; Manning, A	1
Haddeman, E; Hoyng, PF; van Alphen, GW	1
Belur, EB; Chideckel, EW; Rosovski, SJ	1
Miichi, H; Nagataki, S	1
Cross, S; Fliegenspan, J; Szalay, J; Tobin, G; Zaager, A	1
Szalay, J	1
Hexeberg, E; Lekven, J; Segadal, J	1
Abrams, WB; Feinberg, JA; Ferguson, RK; Rotmensch, HH; Vlasses, PH	1
Huupponen, R; Iisalo, E; Kaila, T; Karhuvaara, S	1
Benoit, JP; Chetoni, P; Duval, O; Pech, B; Saettone, MF	1
Bickford, PC; Lin, AM; Palmer, MR	1
Garrido, M; Martinez de Ibarreta, MJ; Pablo, V; Santafe, J; Segarra, J	1
Cappanera, L; Chetoni, P; Conte, U; Finne, U; Järvinen, K; Saettone, MF; Salivirta, J; Urtti, A	1
Patterson, JW; Walsh, SP	1
Bausher, L; Horio, B; Matsui, H; Mead, A; Sears, M	1
Abe, K; Ikegaya, Y; Saito, H; Watanabe, Y	1
Huang, YY; Kandel, ER	1
Berridge, CW; Bolen, SJ; Foote, SL; Manley, MS	1
Nasa, Y; Takeo, S; Yabe, K	1
Barros, MD; Bodor, N; Farag, HH; Prokai, L; Somogyi, G; Wu, WM	1
Berridge, CW	1
Coca-Prados, M; Ortego, J	1
Kaba, H; Okutani, F; Seto, K; Takahashi, S	1
Chang, Q; Chi, OZ; Wang, G; Weiss, HR	1
Borger, P; Esselink, MT; Hoekstra, Y; Kauffman, HF; Postma, DS; Vellenga, E; Zaagsma, J	1
Hannon, JD; Housmans, PR; Johnson, RG; Kranias, EG; Pan, BS; Potter, JD; Shen, YT; Wiedmann, R	1
Hayashi, E; Hayashi-Morimoto, R; Ishikawa, H; Sato, Y; Yoshitomi, T	1
Abuin, L; Cotecchia, S; Lattion, A; Nenniger-Tosato, M	1
Azevedo, I; Borges, N; Sarmento, A	1
Kanikkannan, N; Ramarao, P; Singh, J	1
Dluzen, DE; Ebner, K; Engelmann, M; Landgraf, R; Muraoka, S	1
Ciranna, L; Li Volsi, G; Licata, F; Santangelo, F	1
Obels, PP; van den Thillart, GE; Vianen, GJ; Zaagsma, J	1
Claremon, DA; Gilberto, DB; Jahansouz, H; Liverton, NJ; Lynch, JJ; Salata, JJ; Selnick, HG; Stump, GL; Wallace, AA	1
Adriaan Nelemans, S; Biber, K; Boddeke, HW; Kauffman, HF; Meurs, H; Oostendorp, J; Postma, DS; Zaagsma, J	1
Ardell, JL; Belardi, DF; Forfia, PR; Helm, RH; Hoover, DB; Kass, DA; Katori, T; Paolocci, N; Tocchetti, CG	1
Chiu, TH; Lin, YW; Min, MY; Yang, HW	1
Ghoghawala, SY; Isseroff, RR; Mannis, MJ; Pullar, CE; Rosenblatt, MI	1
Bronzi, D; Di Mauro, M; Li Volsi, G; Licata, F; Lombardo, P; Santangelo, F	1
Boralli, VB; Danhof, M; de Lange, EC; Freijer, J; Krekels, EH; Slijkerman, P; van Steeg, TJ	1
Devost, D; Goupil, E; Hébert, TE; Iorio-Morin, C; Laporte, SA; Pétrin, D; Wrzal, PK; Zingg, HH	1
Croll, RP; Quinn, TA; Smith, FM; Stoyek, MR	1
Ide, S; Minami, M; Takeda, H; Yamamoto, R	1
Ide, S; Minami, M; Suzuki, H; Takeda, H; Yamamoto, R	1
Behling, JAK; Farias, CP; Furini, CRG; Izquierdo, I; Myskiw, JC; Nachtigall, EG	1

Reviews

1 review(s) available for isoproterenol and timolol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

5 trial(s) available for isoproterenol and timolol

Article	Year
Beta-blocking effects of timolol at low plasma concentrations. Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:1 Topics: Adult; Cyclic AMP; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Female; Humans; Isoenzymes; Isoproterenol; Liver; Male; Mixed Function Oxygenases; Receptors, Adrenergic, beta; Timolol	1991
Systemic effects of three beta-blocker eyedrops: comparison in healthy volunteers of beta 1- and beta 2-adrenoreceptor inhibition. Clinical pharmacology and therapeutics, 1990, Volume: 47, Issue:5 Topics: Adrenergic beta-Antagonists; Adult; Betaxolol; Carteolol; Female; Heart Rate; Humans; Isoproterenol; Male; Muscle, Smooth, Vascular; Myocardium; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Timolol	1990
Bronchial beta-adrenoceptor blockade following eyedrops of timolol and its isomer L-714,465 in normal subjects. British journal of clinical pharmacology, 1985, Volume: 20, Issue:5 Topics: Adrenergic beta-Antagonists; Adult; Arrhythmias, Cardiac; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Lung Volume Measurements; Ophthalmic Solutions; Timolol; Vision Disorders	1985
A single dose of three different ophthalmic beta-blockers antagonizes the chronotropic effect of isoproterenol in healthy volunteers. Clinical pharmacology and therapeutics, 1987, Volume: 41, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Carteolol; Double-Blind Method; Heart Rate; Humans; Intraocular Pressure; Isoproterenol; Male; Metipranolol; Ophthalmic Solutions; Random Allocation; Timolol	1987
Comparisons of beta-adrenergic blocking properties of S- and R-timolol in humans. Journal of clinical pharmacology, 1993, Volume: 33, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Fingers; Forearm; Heart Rate; Humans; Isoproterenol; Male; Regional Blood Flow; Stereoisomerism; Timolol; Tremor	1993

Other Studies

113 other study(ies) available for isoproterenol and timolol

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Comparison of the effects of timolol and other adrenergic agents on intraocular pressure in the rabbit. Investigative ophthalmology & visual science, 1977, Volume: 16, Issue:11 Topics: Adrenergic beta-Antagonists; Animals; Aqueous Humor; Chymotrypsin; Disease Models, Animal; Epinephrine; Intraocular Pressure; Isoproterenol; Male; Propanolamines; Propranolol; Rabbits; Sympathomimetics; Timolol; Water	1977
Antihypertensive and beta-adrenoceptor antagonist action of timolol. Clinical pharmacology and therapeutics, 1978, Volume: 23, Issue:2 Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Heart Rate; Humans; Hypertension; Isoproterenol; Male; Middle Aged; Physical Exertion; Propanolamines; Renin; Timolol	1978
Direct myocardial depressant effects of several beta-adrenergic blocking agents in the unanesthetized atherosclerotic rabbit. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:2 Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Arteriosclerosis; Atenolol; Blood Pressure; Depression, Chemical; Heart Rate; Isoproterenol; Male; Oxprenolol; Pindolol; Propanolamines; Propranolol; Rabbits; Timolol	1978
The influence of calcium on the antilipolytic action of propranolol, timolol, labetalol, verapamil, procaine, and papaverine in rat adipocytes. Pharmacological research communications, 1979, Volume: 11, Issue:9 Topics: Adipose Tissue; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Calcium; In Vitro Techniques; Isoproterenol; Labetalol; Lipolysis; Male; Papaverine; Procaine; Propranolol; Rats; Timolol; Vasodilator Agents; Verapamil	1979
In vitro determination of the ability of drugs to bind to adrenergic receptors. Investigative ophthalmology & visual science, 1977, Volume: 16, Issue:12 Topics: Alprenolol; Animals; Ciliary Body; Clonidine; Dihydroergotoxine; Dopamine; Epinephrine; In Vitro Techniques; Iris; Isoproterenol; Male; Phentolamine; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Timolol	1977
The effect of timolol on isoprenaline induced cyclic adenosine monophosphate production in human isolated lymphocytes [proceedings]. British journal of clinical pharmacology, 1979, Volume: 7, Issue:4 Topics: Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Lymphocytes; Propanolamines; Timolol	1979
Modification by timolol of catecholamine stimulation of chloride transport in isolated corneas. Investigative ophthalmology & visual science, 1979, Volume: 18, Issue:7 Topics: Administration, Topical; Animals; Anura; Biological Transport; Catecholamines; Chlorides; Cornea; Epinephrine; In Vitro Techniques; Isoproterenol; Propanolamines; Rabbits; Rana catesbeiana; Timolol	1979
Ocular hypotensive action of labetalol. American journal of ophthalmology, 1979, Volume: 88, Issue:3 Pt 1 Topics: Animals; Ethanolamines; Female; Intraocular Pressure; Isoproterenol; Labetalol; Norepinephrine; p-Hydroxyamphetamine; Phenoxybenzamine; Pupil; Rabbits; Sympathectomy; Timolol	1979
[Sympathomimetic and sympatholytic drugs in the therapy of glaucoma (author's transl)]. Klinische Monatsblatter fur Augenheilkunde, 1977, Volume: 171, Issue:4 Topics: Albuterol; Clonidine; Epinephrine; Glaucoma; Humans; Isoproterenol; Norepinephrine; Propranolol; Sympatholytics; Sympathomimetics; Timolol	1977
Comparative dromotropic activity of timolol and propranolol in anesthetized dogs. European journal of pharmacology, 1978, Jan-15, Volume: 47, Issue:2 Topics: Animals; Atropine; Dogs; Electric Stimulation; Electrocardiography; Female; Heart Conduction System; Heart Rate; Isoproterenol; Male; Neural Conduction; Propanolamines; Propranolol; Time Factors; Timolol	1978
Haemodynamic effects of prazosin. Archives internationales de pharmacodynamie et de therapie, 1976, Volume: 224, Issue:2 Topics: Animals; Atropine; Blood Cell Count; Blood Pressure; Diazoxide; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Hemodynamics; Isoproterenol; Pentolinium Tartrate; Prazosin; Quinazolines; Rats; Renin; Timolol	1976
Differential response of beta-adrenergic receptor-mediated heart rate and aortic blood flow acceleration to timolol. Clinical pharmacology and therapeutics, 1992, Volume: 51, Issue:3 Topics: Adult; Aorta; Blood Flow Velocity; Heart Rate; Heart Ventricles; Humans; Isoproterenol; Receptors, Adrenergic, beta; Sinoatrial Node; Timolol; Ventricular Function, Left	1992
Stimulatory and inhibitory effects of catecholamines on DNA synthesis in primary rat hepatocyte cultures: role of alpha 1- and beta-adrenergic mechanisms. Journal of cellular physiology, 1992, Volume: 151, Issue:1 Topics: Animals; Catecholamines; Cell Division; Cells, Cultured; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epinephrine; G1 Phase; Insulin; Isoproterenol; Liver; Male; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; S Phase; Time Factors; Timolol	1992
Comparison of methods to assess cyclic AMP turnover under conditions of agonist stimulation in 1321N1 astrocytoma cells. Biochemical Society transactions, 1992, Volume: 20, Issue:2 Topics: Adenine; Adenosine Triphosphate; Animals; Astrocytoma; Carbon Radioisotopes; Cell Line; Cyclic AMP; Humans; Isoproterenol; Kinetics; Lymphoma; Radioisotope Dilution Technique; Radioligand Assay; Receptors, Adrenergic, beta; Timolol	1992
Cardiac effects of different eyedrop preparations of timolol in rabbits. Current eye research, 1992, Volume: 11, Issue:5 Topics: Animals; Carboxymethylcellulose Sodium; Female; Heart Rate; Isoproterenol; Male; Ophthalmic Solutions; Phenylephrine; Rabbits; Timolol; Viscosity	1992
Pyramidal neurons in immature rat hippocampus are sensitive to beta-adrenergic agents. Brain research. Developmental brain research, 1992, May-22, Volume: 67, Issue:1 Topics: Action Potentials; Adaptation, Physiological; Animals; Electric Conductivity; Hippocampus; Isoproterenol; Membrane Potentials; Neurons; Rats; Rats, Inbred Strains; Timolol	1992
Norepinephrine-induced plasticity and one-trial olfactory learning in neonatal rats. Brain research. Developmental brain research, 1991, Jun-21, Volume: 60, Issue:2 Topics: Animals; Animals, Newborn; Brain; Conditioning, Psychological; Deoxyglucose; Female; Handling, Psychological; Isoproterenol; Learning; Male; Norepinephrine; Odorants; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Smell; Timolol	1991
Beta 1- and beta 2-adrenoceptor subtypes in canine intrathoracic efferent sympathetic nervous system regulating the heart. The American journal of physiology, 1991, Volume: 261, Issue:5 Pt 2 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Atropine; Axons; Dogs; Efferent Pathways; Electric Stimulation; Female; Ganglia, Sympathetic; Heart Conduction System; Isoproterenol; Male; Myocardial Contraction; Propanolamines; Receptors, Adrenergic, beta; Stellate Ganglion; Sympathetic Nervous System; Timolol	1991
In vivo functional implications of isoproterenol-mediated relaxation of isolated human iris sphincter. Journal of ocular pharmacology, 1991,Winter, Volume: 7, Issue:4 Topics: Aged; Aged, 80 and over; Carbachol; Ciliary Body; Humans; Iris; Isoproterenol; Muscle Relaxation; Pupil; Temperature; Timolol	1991
Sensitization enhances the adenylyl cyclase responsiveness in alveolar macrophages. Changes induced at post-receptor level. Biochemical pharmacology, 1991, Jul-15, Volume: 42, Issue:3 Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Dinoprostone; Enzyme Activation; GTP-Binding Proteins; Guinea Pigs; Iodocyanopindolol; Isoproterenol; Macrophage Activation; Macrophages; Male; Ovalbumin; Pindolol; Pulmonary Alveoli; Signal Transduction; Timolol	1991
Pharmacodynamic effects of transdermal bupranolol and timolol in vivo: comparison of microemulsions and matrix patches as vehicle. Methods and findings in experimental and clinical pharmacology, 1991, Volume: 13, Issue:5 Topics: Administration, Cutaneous; Animals; Bupranolol; Emulsions; Heart Rate; Isoproterenol; Pharmaceutical Vehicles; Rabbits; Timolol	1991
[Changes in ocular hypotensive effect of griseolic acid with isoproterenol, timolol and melanin]. Nippon Ganka Gakkai zasshi, 1990, Volume: 94, Issue:7 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Depression, Chemical; Drug Synergism; Female; Intraocular Pressure; Isoproterenol; Male; Melanins; Rabbits; Timolol	1990
Influence of AQ-A39, a bradycardic agent, on cardiovascular responses to isoproterenol in the anesthetized dog. Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:2 Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular System; Dogs; Drug Interactions; Female; Heart Rate; Isoindoles; Isoproterenol; Male; Myocardial Contraction; Phthalimides; Timolol; Verapamil	1987
Role of cyclic AMP-dependent protein kinase in the diminished beta adrenergic responsiveness of vascular smooth muscle with increasing age. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:3 Topics: Aging; Animals; Aorta; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Timolol	1989
86Rb(K) influx and [3H]ouabain binding by human platelets: evidence for beta-adrenergic stimulation of Na-K ATPase activity. Metabolism: clinical and experimental, 1989, Volume: 38, Issue:8 Topics: Adult; Albuterol; Atenolol; Biological Transport, Active; Blood Platelets; Cell Membrane; Epinephrine; Humans; Isoproterenol; Norepinephrine; Ouabain; Phentolamine; Potassium; Receptors, Adrenergic, beta; Rubidium Radioisotopes; Sodium-Potassium-Exchanging ATPase; Timolol; Tritium	1989
Differential inhibition of beta adrenergic receptors in human and rabbit ciliary process and heart. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1 Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Adult; Aged; Animals; Ciliary Body; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Kinetics; Male; Methylation; Middle Aged; Myocardium; Propanolamines; Propranolol; Rabbits; Receptors, Adrenergic, beta; Timolol	1985
Comparison of the effects of adrenergic agonists and alpha-, beta 1-, beta 2-antagonists on the intraocular pressure and adenylate cyclase activity in the ciliary processes of the rabbit. Acta ophthalmologica, 1985, Volume: 63, Issue:1 Topics: Acebutolol; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Ciliary Body; Intraocular Pressure; Isoproterenol; Labetalol; Metoprolol; Rats; Timolol; Water	1985
Biochemical and physiological effects of S-32-468, a beta-adrenoceptor antagonist with possible oculoselectivity. Current eye research, 1985, Volume: 4, Issue:3 Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Ciliary Body; Enzyme Activation; Humans; Intraocular Pressure; Isoproterenol; Lung; Male; Myocardium; Propanolamines; Rabbits; Timolol	1985
Beta-adrenergic [( 3H]CGP-12177) binding to brain slices and single intact pineal glands. Neurochemical research, 1985, Volume: 10, Issue:6 Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Brain; Cerebral Cortex; Cricetinae; In Vitro Techniques; Isoproterenol; Kinetics; Male; Mesocricetus; Phentolamine; Pineal Gland; Propanolamines; Rats; Rats, Inbred Strains; Timolol	1985
Pharmacological characterization of beta-adrenoceptor subtype involvement in the ocular hypotensive response to beta-adrenergic stimulation. Experimental eye research, 1986, Volume: 43, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Female; Intraocular Pressure; Isoproterenol; Male; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Time Factors; Timolol	1986
Rotifer neuropharmacology--III. Adrenergic drug effects on Brachionus plicatilis. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1987, Volume: 86, Issue:2 Topics: Albuterol; Animals; Cilia; Dose-Response Relationship, Drug; Isoproterenol; Movement; Norepinephrine; Phenylephrine; Propranolol; Receptors, Adrenergic; Rotifera; Timolol; Tolazoline	1987
Topical timolol, at conventional, unilateral doses causes bilateral ocular beta-blockade in rabbits. Experimental eye research, 1987, Volume: 44, Issue:2 Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Eye; Female; Heart Rate; Intraocular Pressure; Isoproterenol; Male; Rabbits; Time Factors; Timolol	1987
Stereospecificity of beta adrenergic antagonists: R-enantiomers show increased selectivity for beta-2 receptors in ciliary process. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1 Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Betaxolol; Ciliary Body; Heart; Isoproterenol; Male; Metoprolol; Myocardium; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Stereoisomerism; Structure-Activity Relationship; Timolol	1988
[Asthma and beta-blocker eye drops (timolol, metipranolol, carteolol). Inhibition of chronotropic effects of isoprenaline]. Allergie et immunologie, 1988, Volume: 20, Issue:7 Topics: Adult; Asthma; Blood Pressure; Carteolol; Heart Rate; Humans; Isoproterenol; Metipranolol; Middle Aged; Ophthalmic Solutions; Propanolamines; Respiration; Timolol	1988
Ocular and cardiac beta-antagonism by timolol prodrugs, timolol and levobunolol. Current eye research, 1988, Volume: 7, Issue:8 Topics: Adrenergic beta-Antagonists; Animals; Eye; Heart; Heart Rate; Intraocular Pressure; Isoproterenol; Levobunolol; Male; Prodrugs; Rabbits; Timolol	1988
Alpha noradrenergic agonists promote catalepsy in the mouse. Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Catalepsy; Clonidine; Isoproterenol; Mice; Models, Biological; Motor Activity; Phenoxybenzamine; Phenylephrine; Timolol; Yohimbine	1988
[Cyclic-nucleotides and adrenergic antiglaucoma drugs]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 1985, Volume: 21, Issue:1 Topics: Animals; Aqueous Humor; Cyclic AMP; Cyclic GMP; Intraocular Pressure; Isoproterenol; Norepinephrine; Pupil; Rabbits; Timolol	1985
The relationship between tonic accommodation and ciliary muscle innervation. Investigative ophthalmology & visual science, 1985, Volume: 26, Issue:7 Topics: Accommodation, Ocular; Adult; Ciliary Body; Female; Humans; Isoproterenol; Male; Muscle Tonus; Parasympathetic Nervous System; Receptors, Adrenergic, beta; Receptors, Muscarinic; Reflex, Pupillary; Sympathetic Nervous System; Timolol; Tropicamide	1985
Effect of alpha- and beta-receptor active drugs on corneal thickness. Acta ophthalmologica, 1985, Volume: 63, Issue:3 Topics: Adult; Cornea; Humans; Isoproterenol; Middle Aged; Phentolamine; Phenylephrine; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Timolol	1985
Tonic beta-sympathetic activity in the lung periphery in anesthetized dogs. Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 59, Issue:3 Topics: Adrenalectomy; Aerosols; Airway Resistance; Animals; Atropine; Dogs; Isoproterenol; Lung; Male; Propranolol; Receptors, Adrenergic, beta; Stereoisomerism; Sympathetic Nervous System; Timolol	1985
Beta-adrenergic receptors in the elderly are not less sensitive to timolol. Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:2 Topics: Adult; Aged; Aging; Blood Pressure; Female; Heart Rate; Humans; Injections, Intravenous; Isoproterenol; Male; Middle Aged; Receptors, Adrenergic, beta; Timolol	1986
The effects of timolol on the active transport across the ciliary epithelium. Transactions of the ophthalmological societies of the United Kingdom, 1986, Volume: 105 ( Pt 6) Topics: Animals; Biological Transport, Active; Ciliary Body; Epithelium; In Vitro Techniques; Iris; Isoproterenol; Membrane Potentials; Rabbits; Sodium; Timolol	1986
Adrenergic stimulation of ciliary process epithelium causes surface membrane internalization. Investigative ophthalmology & visual science, 1987, Volume: 28, Issue:3 Topics: Administration, Topical; Animals; Ciliary Body; Endoplasmic Reticulum; Extracellular Space; Ferritins; Isoproterenol; Lysosomes; Microscopy, Electron; Rabbits; Stimulation, Chemical; Sympathomimetics; Timolol	1987
Pharmacological study on the effects of some ocular hypotensive drugs on aqueous humor formation in the arterially perfused enucleated rabbit eye. Ophthalmic research, 1985, Volume: 17, Issue:2 Topics: Acetazolamide; Animals; Aqueous Humor; Arteries; Autonomic Agents; Dinitrophenols; Epinephrine; In Vitro Techniques; Intraocular Pressure; Isoproterenol; Ouabain; Perfusion; Pilocarpine; Rabbits; Time Factors; Timolol	1985
Frequency-dependent noradrenergic modulation of long-term potentiation in the hippocampus. Science (New York, N.Y.), 1984, Oct-19, Volume: 226, Issue:4672 Topics: Adrenergic Fibers; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Timolol	1984
Adrenergic drugs and intraocular pressure: suppression of ocular hypertension induced by water loading. Experimental eye research, 1980, Volume: 30, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Dobutamine; Ephedrine; Epinephrine; Intraocular Pressure; Isoproterenol; Male; Metoprolol; Propranolol; Pupil; Rabbits; Sympathomimetics; Terbutaline; Timolol; Water	1980
Pharmacological effects of topical timolol in the rabbit eye. Investigative ophthalmology & visual science, 1980, Volume: 19, Issue:10 Topics: Adrenergic beta-Antagonists; Animals; Ciliary Body; Cyclic AMP; Eye; In Vitro Techniques; Intraocular Pressure; Iris; Isoproterenol; Propanolamines; Rabbits; Timolol	1980
Urinary metabolites of timolol from humans and laboratory animals. Syntheses and beta-adrenergic blocking activities. Journal of medicinal chemistry, 1980, Volume: 23, Issue:11 Topics: Adrenergic beta-Antagonists; Animals; Dogs; Female; Gas Chromatography-Mass Spectrometry; Humans; Isoproterenol; Male; Propanolamines; Timolol	1980
Comparison of four different beta-adrenoceptor blocking drugs on lymphocyte isoprenaline-stimulated cyclic AMP production. British journal of clinical pharmacology, 1981, Volume: 11, Issue:6 Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Cyclic AMP; Drug Interactions; Female; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Pindolol; Timolol	1981
Actions of non-cardiodepressant beta-adrenergic blocking agents in hemorrhagic shock. Advances in shock research, 1980, Volume: 3 Topics: Adrenergic beta-Antagonists; Animals; Cats; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardial Depressant Factor; Propanolamines; Pyridines; Shock, Hemorrhagic; Timolol	1980
Properties of beta-adrenoceptor sites in metabolizing and nonmetabolizing rat reticulocytes and in resealed reticulocyte ghosts. Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 317, Issue:4 Topics: Adrenergic beta-Antagonists; Animals; Cell Membrane; Cold Temperature; Cytosol; Dihydroalprenolol; Energy Metabolism; Female; Isoproterenol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reticulocytes; Timolol	1981
High and low (Gpp(NH)p-sensitive) affinity sites for beta 2-adrenergic blockers as antagonists of isoproterenol in the field-stimulated rat vas deferens. European journal of pharmacology, 1982, Oct-22, Volume: 84, Issue:3-4 Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Electric Stimulation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Timolol; Vas Deferens	1982
Beta-adrenergic and serotonergic responsiveness of rabbit corneal epithelial cells in culture. Investigative ophthalmology & visual science, 1983, Volume: 24, Issue:8 Topics: Adrenergic beta-Agonists; Animals; Cell Division; Cells, Cultured; Cornea; Epithelial Cells; Epithelium; Isoproterenol; Rabbits; Serotonin; Timolol	1983
Beta-blockers in isoproterenol-enhanced essential tremor. Acta neurologica Scandinavica, 1984, Volume: 69, Issue:2 Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Humans; Isoproterenol; Metoprolol; Middle Aged; Propranolol; Timolol; Tremor	1984
ICI 118,551: an effective ocular hypotensive agent with selectivity for the ciliary process beta 2-adrenoceptor and with minimal cardiac side effects. British journal of pharmacology, 1984, Volume: 83, Issue:3 Topics: Adenylyl Cyclase Inhibitors; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Ciliary Body; Heart Rate; In Vitro Techniques; Intraocular Pressure; Isoproterenol; Lung; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Timolol	1984
Beta-adrenergic receptors in ciliary processes of the rabbit. Investigative ophthalmology & visual science, 1980, Volume: 19, Issue:2 Topics: Adenylyl Cyclases; Alprenolol; Animals; Cell Membrane; Ciliary Body; Epinephrine; Isoproterenol; Male; Phentolamine; Pindolol; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, beta; Timolol	1980
Noradrenergic responses in rat hippocampus: evidence for medication by alpha and beta receptors in the in vitro slice. Brain research, 1981, Jun-09, Volume: 214, Issue:1 Topics: Animals; Clonidine; Culture Techniques; Cyclic AMP; Evoked Potentials; Hippocampus; Isoproterenol; Male; Norepinephrine; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Thionucleotides; Timolol	1981
The effect of hypotensive drugs on the intraocular pressure after waterloading in rabbits. Documenta ophthalmologica. Advances in ophthalmology, 1981, Dec-16, Volume: 52, Issue:2 Topics: Acetazolamide; Animals; Antihypertensive Agents; Dronabinol; Epinephrine; Intraocular Pressure; Isoproterenol; Physostigmine; Pilocarpine; Rabbits; Time Factors; Timolol; Water	1981
Antagonism with dibenamine, D-600, and Ro 3-7894 to estimate dissociation constants and receptor reserves for cardiac adrenoceptors in isolated rabbit papillary muscles. Canadian journal of physiology and pharmacology, 1982, Volume: 60, Issue:8 Topics: Animals; Benzofurans; Dibenzylchlorethamine; Female; Gallopamil; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phenylephrine; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Timolol	1982
Characterization of the adrenoreceptor activities of isoprenaline in the field stimulated rat vas deferens: selective supersensitivity to beta 2-mediated responses following reserpine treatment. Journal of autonomic pharmacology, 1982, Volume: 2, Issue:3 Topics: Animals; Isoproterenol; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reserpine; Timolol; Vas Deferens; Yohimbine	1982
Inotropic responses, cyclic AMP, and time to peak tension in isolated cardiac preparations. Advances in myocardiology, 1982, Volume: 3 Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gallopamil; Glucagon; Guinea Pigs; Histamine; Ion Channels; Isoproterenol; Male; Myocardial Contraction; Propranolol; Rats; Rats, Inbred Strains; Timolol	1982
Evidence that beta 1-adrenoceptor activation mediates isoproterenol-stimulated renin secretion in the rat. Endocrinology, 1983, Volume: 113, Issue:2 Topics: Animals; Atenolol; In Vitro Techniques; Isoproterenol; Kidney Cortex; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Renin; Timolol	1983
An altered beta-adrenoreceptor-mediated modulation of noradrenaline-induced vasoconstriction in spontaneously hypertensive rat mesenteric arteries. Journal of autonomic pharmacology, 1984, Volume: 4, Issue:1 Topics: Animals; Hypertension; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stereoisomerism; Timolol; Vasoconstriction; Yohimbine	1984
Forskolin lowers intraocular pressure by reducing aqueous inflow. Investigative ophthalmology & visual science, 1984, Volume: 25, Issue:3 Topics: Adenylyl Cyclases; Animals; Aqueous Humor; Blood Pressure; Ciliary Body; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Female; Humans; In Vitro Techniques; Intraocular Pressure; Iris; Isoproterenol; Macaca; Male; Rabbits; Regional Blood Flow; Timolol	1984
Protective effect of timolol as assessed by energy charge during myocardial ischaemia. Biochemical pharmacology, 1983, Sep-15, Volume: 32, Issue:18 Topics: Adenine Nucleotides; Animals; Coronary Disease; Energy Metabolism; Heart; Heart Rate; Isoproterenol; Kinetics; Male; Myocardium; Phosphocreatine; Rats; Rats, Inbred Strains; Timolol	1983
Does prostacyclin mediate alpha-adrenergic induced hypotension? Documenta ophthalmologica. Advances in ophthalmology, 1982, Sep-30, Volume: 53, Issue:2 Topics: Animals; Aqueous Humor; Epinephrine; Epoprostenol; Indomethacin; Intraocular Pressure; Iris; Isoproterenol; Norepinephrine; Phenoxybenzamine; Rabbits; Timolol; Tranylcypromine	1982
Catecholamine-thyroid hormone interaction on myocardial ornithine decarboxylase. The American journal of physiology, 1982, Volume: 243, Issue:4 Topics: Animals; Body Weight; Carboxy-Lyases; Heart; Hyperthyroidism; Isoproterenol; Kinetics; Male; Myocardium; Organ Size; Ornithine Decarboxylase; Propanolamines; Rats; Rats, Inbred Strains; Timolol	1982
Effects of cholinergic drugs and adrenergic drugs on aqueous humor formation in the rabbit eye. Japanese journal of ophthalmology, 1982, Volume: 26, Issue:4 Topics: Albuterol; Animals; Aqueous Humor; Atropine; Epinephrine; Female; Intraocular Pressure; Isoproterenol; Male; Norepinephrine; Parasympathomimetics; Physostigmine; Pilocarpine; Propranolol; Rabbits; Sympathomimetics; Timolol	1982
Effect of beta adrenergic agents on blood vessels of the rat iris. I. Permeability to carbon particles. Experimental eye research, 1980, Volume: 31, Issue:3 Topics: Aging; Aminophylline; Animals; Capillary Permeability; Carbon; Iris; Isoproterenol; Male; Propanolamines; Prostaglandins E; Rats; Timolol; Tolazoline	1980
Effect of beta adrenergic agents on blood vessels of the rat iris. II. Morphological modifications of the vessel wall. Experimental eye research, 1980, Volume: 31, Issue:3 Topics: Aging; Animals; Capillary Permeability; Carbon; Endothelium; Iris; Isoproterenol; Male; Microscopy, Electron; Rats; Timolol; Venules	1980
Beta-adrenergic blockade improves uniformity of local contraction in the anterior wall of feline left ventricles. Clinical physiology (Oxford, England), 1993, Volume: 13, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiac Output; Cats; Coronary Circulation; Electrodes, Implanted; Electrophysiology; Heart Rate; Isoproterenol; Male; Microspheres; Myocardial Contraction; Timolol; Ventricular Function, Left	1993
The analysis of plasma kinetics and beta-receptor binding and -blocking activity of timolol following its small intravenous dose. International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:7 Topics: Adrenergic beta-Antagonists; Adult; Animals; Female; Finland; Humans; Injections, Intravenous; Isoproterenol; Lung; Male; Mice; Protein Binding; Rabbits; Receptors, Adrenergic, beta; Reticulocytes; Timolol	1993
Preliminary evaluation of a series of amphiphilic timolol prodrugs: possible evidence for transscleral absorption. Journal of ocular pharmacology, 1993,Summer, Volume: 9, Issue:2 Topics: Absorption; Animals; Cell Membrane Permeability; Cornea; Disease Models, Animal; Esters; Evaluation Studies as Topic; Intraocular Pressure; Isoproterenol; Ocular Hypertension; Pilot Projects; Prodrugs; Rabbits; Sclera; Solubility; Timolol	1993
The effects of ethanol on gamma-aminobutyric acid-induced depressions of cerebellar Purkinje neurons: influence of beta adrenergic receptor action in young and aged Fischer 344 rats. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2 Topics: Aging; Animals; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Isoproterenol; Male; Purkinje Cells; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Timolol	1993
Evidence for a synergistic interaction between isoprenaline and timolol on intraocular pressure in conscious rabbits. General pharmacology, 1993, Volume: 24, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Intraocular Pressure; Isoproterenol; Rabbits; Receptors, Adrenergic, beta; Timolol	1993
Intraocular pressure reduction and systemic absorption of timolol after administration of one side-coated inserts in rabbits. Journal of ocular pharmacology, 1993,Spring, Volume: 9, Issue:1 Topics: Absorption; Animals; Biological Availability; Drug Carriers; Drug Delivery Systems; Intraocular Pressure; Isoproterenol; Male; Ocular Hypotension; Ophthalmic Solutions; Rabbits; Tears; Timolol	1993
Topical norepinephrine, isoproterenol, terbutaline, forskolin and 8-bromo cyclic AMP increase lens equatorial current. Experimental eye research, 1993, Volume: 56, Issue:3 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Administration, Topical; Animals; Colforsin; Electric Conductivity; In Vitro Techniques; Isoproterenol; Lens, Crystalline; Norepinephrine; Rana pipiens; Terbutaline; Timolol	1993
Regulation and bioelectrical effects of cyclic adenosine monophosphate production in the ciliary epithelial bilayer. Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Ciliary Body; Clonidine; Colforsin; Cyclic AMP; Electrophysiology; Isoproterenol; Male; Membrane Potentials; Pigment Epithelium of Eye; Rabbits; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Timolol; Vasoactive Intestinal Peptide	1996
Opposite regulation by the beta-adrenoceptor-cyclic AMP system of synaptic plasticity in the medial and lateral amygdala in vitro. Neuroscience, 1996, Volume: 71, Issue:4 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Amygdala; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Male; Neuronal Plasticity; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Synapses; Synaptic Transmission; Timolol	1996
Modulation of both the early and the late phase of mossy fiber LTP by the activation of beta-adrenergic receptors. Neuron, 1996, Volume: 16, Issue:3 Topics: Animals; Isoproterenol; Long-Term Potentiation; Models, Neurological; Nerve Fibers; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Time Factors; Timolol	1996
Modulation of forebrain electroencephalographic activity in halothane-anesthetized rat via actions of noradrenergic beta-receptors within the medial septal region. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Nov-01, Volume: 16, Issue:21 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthetics, Inhalation; Animals; Antibody Specificity; Arousal; Atropine; Cerebral Cortex; Dopamine beta-Hydroxylase; Electroencephalography; Glutamic Acid; Halothane; Hippocampus; Injections, Intraventricular; Isoproterenol; Locus Coeruleus; Male; Microinjections; Muscarinic Antagonists; Neurons; Norepinephrine; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Septal Nuclei; Timolol	1996
Beta-adrenoceptor stimulation-mediated preconditioning-like cardioprotection in perfused rat hearts. Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Creatine Kinase; Heart; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Norepinephrine; Phenylephrine; Quinazolines; Random Allocation; Rats; Rats, Sprague-Dawley; Timolol; Ventricular Function, Left	1997
Ocular-specific delivery of timolol by sequential bioactivation of its oxime and methoxime analogs. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1997, Volume: 13, Issue:5 Topics: Administration, Topical; Adrenergic beta-Agonists; Animals; Eye; Hydrolysis; Intraocular Pressure; Isoproterenol; Kinetics; Male; Rabbits; Rats; Rats, Sprague-Dawley; Tachycardia; Timolol	1997
Modulation of forebrain electroencephalographic activity and behavioral state by the locus ceruleus-noradrenergic system: involvement of the medial septal area. Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42 Topics: Adrenergic beta-Antagonists; Animals; Brain Mapping; Drinking; Eating; Efferent Pathways; Electroencephalography; Frontal Lobe; Grooming; Hippocampus; Isoproterenol; Locus Coeruleus; Norepinephrine; Prosencephalon; Rats; Sleep Stages; Sleep, REM; Timolol; Wakefulness	1998
Molecular characterization and differential gene induction of the neuroendocrine-specific genes neurotensin, neurotensin receptor, PC1, PC2, and 7B2 in the human ocular ciliary epithelium. Journal of neurochemistry, 1997, Volume: 69, Issue:5 Topics: Aspartic Acid Endopeptidases; Cell Line; Ciliary Body; Colforsin; Dexamethasone; DNA Primers; Enzyme Induction; Epithelial Cells; Furin; Gene Expression Regulation; Humans; Isoproterenol; Models, Biological; Nerve Growth Factors; Neurosecretory Systems; Neurotensin; Polymerase Chain Reaction; Proprotein Convertase 2; Proprotein Convertases; Receptors, Neurotensin; Subtilisins; Tetradecanoylphorbol Acetate; Timolol; Transcriptional Activation; Up-Regulation	1997
The biphasic effects of locus coeruleus noradrenergic activation on dendrodendritic inhibition in the rat olfactory bulb. Brain research, 1998, Feb-09, Volume: 783, Issue:2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Dendrites; Electric Stimulation; Evoked Potentials; Female; Glutamic Acid; Isoproterenol; Locus Coeruleus; Neural Inhibition; Neurons; Norepinephrine; Olfactory Bulb; Phentolamine; Rats; Rats, Wistar; Receptors, Adrenergic; Smell; Timolol	1998
Effects of isoproterenol on blood-brain barrier permeability in rats. Neurological research, 1998, Volume: 20, Issue:3 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aminoisobutyric Acids; Animals; Blood Gas Analysis; Blood Pressure; Blood-Brain Barrier; Carbon Radioisotopes; Heart Rate; Isoproterenol; Rats; Rats, Inbred Strains; Timolol	1998
Beta-adrenoceptor-mediated inhibition of IFN-gamma, IL-3, and GM-CSF mRNA accumulation in activated human T lymphocytes is solely mediated by the beta2-adrenoceptor subtype. American journal of respiratory cell and molecular biology, 1998, Volume: 19, Issue:3 Topics: Concanavalin A; Cyclic AMP; Ethanolamines; Fenoterol; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interferon-gamma; Interleukin-3; Interleukin-4; Isoproterenol; Receptors, Adrenergic, beta-2; RNA, Messenger; T-Lymphocytes; Timolol	1998
Effects of isoproterenol on twitch contraction of wild type and phospholamban-deficient murine ventricular myocardium. Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1 Topics: Adrenergic Agonists; Animals; Calcium-Binding Proteins; Cardiotonic Agents; Dose-Response Relationship, Drug; Electrophysiology; Heart Ventricles; Isoproterenol; Mice; Mice, Knockout; Muscle Contraction; Time Factors; Timolol	1999
Effects of beta antagonists on mechanical properties in rabbit ciliary artery. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1999, Volume: 237, Issue:8 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Carteolol; Cholinergic Agonists; Ciliary Arteries; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoproterenol; Male; Muscle, Smooth, Vascular; Phenylephrine; Rabbits; Receptors, Adrenergic, alpha-1; Timolol; Vasoconstriction	1999
Constitutively active mutants of the beta1-adrenergic receptor. FEBS letters, 1999, Sep-03, Volume: 457, Issue:3 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino Acid Substitution; Betaxolol; Carbazoles; Carvedilol; Cell Line; Cyclic AMP; Epinephrine; Humans; Imidazoles; Isoproterenol; Labetalol; Point Mutation; Practolol; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Recombinant Proteins; Timolol	1999
Dynamics of experimental vasogenic brain oedema in the rat: changes induced by adrenergic drugs. Journal of autonomic pharmacology, 1999, Volume: 19, Issue:4 Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Brain Edema; Capillaries; Cerebral Cortex; Clenbuterol; Cold Temperature; Evans Blue; Injections, Intraventricular; Isoproterenol; Male; Phenoxybenzamine; Rats; Rats, Wistar; Timolol	1999
Transdermal iontophoretic delivery of timolol maleate in albino rabbits. International journal of pharmaceutics, 2000, Mar-20, Volume: 197, Issue:1-2 Topics: Administration, Cutaneous; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Area Under Curve; Azepines; Emulsions; Excipients; Half-Life; Injections, Intravenous; Iontophoresis; Isoproterenol; Liver; Rabbits; Solutions; Tachycardia; Timolol	2000
Oxytocin induces preservation of social recognition in male rats by activating alpha-adrenoceptors of the olfactory bulb. The European journal of neuroscience, 2000, Volume: 12, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Clonidine; Isoproterenol; Male; Memory; Microdialysis; Norepinephrine; Olfactory Bulb; Oxytocin; Phentolamine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Oxytocin; Social Behavior; Social Dominance; Timolol	2000
Neurotransmitter-mediated control of neuronal firing in the red nucleus of the rat: reciprocal modulation between noradrenaline and GABA. Experimental neurology, 2000, Volume: 163, Issue:1 Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bicuculline; Clonidine; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Isoproterenol; Male; Neurons; Neurotransmitter Agents; Nipecotic Acids; Norepinephrine; Rats; Rats, Wistar; Red Nucleus; Timolol; Yohimbine	2000
Beta-adrenoceptors mediate inhibition of lipolysis in adipocytes of tilapia (Oreochromis mossambicus). American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:2 Topics: Adipocytes; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Glucose; Cells, Cultured; Fatty Acids, Nonesterified; Female; Hypoxia; Isoproterenol; Lactic Acid; Lipolysis; Male; Neurotransmitter Agents; Norepinephrine; Phenethylamines; Phentolamine; Receptors, Adrenergic, beta; Tilapia; Timolol	2002
Antiarrhythmic efficacy of combined I(Ks) and beta-adrenergic receptor blockade. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:1 Topics: Acetamides; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Benzodiazepinones; Dogs; Electric Stimulation; Electrophysiology; Female; Heart; Heart Rate; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Myocardial Infarction; Myocardial Ischemia; Potassium Channel Blockers; Timolol; Ventricular Function	2002
Cloning, pharmacological characterization, and polymorphism screening of the guinea pig beta(2)-adrenoceptor. European journal of pharmacology, 2002, Dec-13, Volume: 457, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino Acid Sequence; Animals; CHO Cells; Cloning, Molecular; Cricetinae; Guinea Pigs; Humans; Isoproterenol; Molecular Sequence Data; Polymorphism, Genetic; Radioligand Assay; Receptors, Adrenergic, beta-2; Sequence Homology, Amino Acid; Timolol; Transfection	2002
Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure. Circulation research, 2005, Feb-04, Volume: 96, Issue:2 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcitonin Gene-Related Peptide; Cardiac Pacing, Artificial; Cardiotonic Agents; Dogs; Extracellular Fluid; Femoral Artery; Heart Failure; Hemodynamics; Humans; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Norepinephrine; Peptide Fragments; Receptors, Adrenergic, beta; Receptors, Calcitonin Gene-Related Peptide; Signal Transduction; Sympathetic Nervous System; Tachycardia; Timolol; Vasodilation	2005
Inhibition of associative long-term depression by activation of beta-adrenergic receptors in rat hippocampal CA1 synapses. Journal of biomedical science, 2008, Volume: 15, Issue:1 Topics: Animals; Calcineurin; Cyclic AMP-Dependent Protein Kinases; Hippocampus; In Vitro Techniques; Isoproterenol; Long-Term Synaptic Depression; MAP Kinase Signaling System; Pyrethrins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, N-Methyl-D-Aspartate; Synapses; Timolol	2008
Beta2-adrenergic receptor signaling mediates corneal epithelial wound repair. Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:5 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cell Movement; Epinephrine; Epithelium, Corneal; Extracellular Signal-Regulated MAP Kinases; Immunoblotting; Isoproterenol; Male; Mice; Mice, Knockout; Phosphorylation; Receptors, Adrenergic, beta-2; Signal Transduction; Timolol; Tyrosine 3-Monooxygenase; Wound Healing	2008
Noradrenaline modulates neuronal responses to GABA in vestibular nuclei. Neuroscience, 2008, Jun-02, Volume: 153, Issue:4 Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Iontophoresis; Isoproterenol; Neural Inhibition; Neurons; Norepinephrine; Rats; Rats, Wistar; Timolol; Vestibular Nuclei; Yohimbine	2008
Influence of plasma protein binding on pharmacodynamics: Estimation of in vivo receptor affinities of beta blockers using a new mechanism-based PK-PD modelling approach. Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:10 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Blood Proteins; Dose-Response Relationship, Drug; Heart Rate; Isoproterenol; Male; Metoprolol; Models, Biological; Propranolol; Protein Binding; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Timolol	2009
Allosteric interactions between the oxytocin receptor and the β2-adrenergic receptor in the modulation of ERK1/2 activation are mediated by heterodimerization. Cellular signalling, 2012, Volume: 24, Issue:1 Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Allosteric Regulation; Atenolol; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Humans; Immunoprecipitation; Isoproterenol; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myometrium; Oxytocin; Phosphorylation; Propranolol; Protein Binding; Protein Multimerization; Receptors, Adrenergic, beta-2; Receptors, Oxytocin; Recombinant Fusion Proteins; Signal Transduction; Timolol; Vasotocin	2012
Zebrafish heart as a model to study the integrative autonomic control of pacemaker function. American journal of physiology. Heart and circulatory physiology, 2016, 09-01, Volume: 311, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Atrioventricular Node; Atropine; Autonomic Nervous System; Bradycardia; Electrocardiography; Heart; Heart Rate; Hexamethonium; Isolated Heart Preparation; Isoproterenol; Models, Animal; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parasympathetic Nervous System; Receptor, Muscarinic M2; Receptors, Adrenergic, beta-2; Sinoatrial Node; Sympathetic Nervous System; Sympathomimetics; Tachycardia; Timolol; Vagus Nerve Stimulation; Zebrafish	2016
Bidirectional brain-gut interactions: Involvement of noradrenergic transmission within the ventral part of the bed nucleus of the stria terminalis. Neuropsychopharmacology reports, 2018, Volume: 38, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Gastric Emptying; Gastrointestinal Transit; Intestine, Small; Isoproterenol; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Septal Nuclei; Synaptic Transmission; Timolol	2018
Roles of noradrenergic transmission within the ventral part of the bed nucleus of the stria terminalis in bidirectional brain-intestine interactions. Neuropsychopharmacology reports, 2018, Volume: 38, Issue:4 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colon; Gastrointestinal Transit; Isoproterenol; Male; Nociception; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Septal Nuclei; Synaptic Transmission; Timolol	2018
Facilitation of fear extinction by novelty is modulated by β-adrenergic and 5-HT Neurobiology of learning and memory, 2019, Volume: 166 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Association Learning; Conditioning, Classical; Extinction, Psychological; Fear; Hippocampus; Isoproterenol; Male; Rats, Wistar; Serotonin Receptor Agonists; Timolol	2019