isoproterenol and thiophenes

isoproterenol has been researched along with thiophenes in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199010 (41.67)18.7374
1990's6 (25.00)18.2507
2000's3 (12.50)29.6817
2010's3 (12.50)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Bauthier, J; Charlier, R; Richard, J1
Kompa, AR; Molenaar, P; Pak, HS; Roberts, SJ; Summers, RJ1
Bond, RA; Vanhoutte, PM1
Ishii, K; Taira, N; Yanagisawa, T1
Herman, AG; Jordaens, FH; Laekeman, G; Majchrowicz, BB; Verbeuren, TJ; Zonnekeyn, LL1
Herman, AG; Verbeuren, TJ1
Hori, M; Inoue, M; Ito, H; Iwai, K; Kamada, T; Kitabatake, A; Kitakaze, M; Koretsune, Y; Tamai, J1
Corral, C; Darias, V; Del Río, J; Fernández-Tomé, MP; Madroñero, R1
Ferguson, EW; Mielens, ZE; Rosenberg, FJ1
Darias, V; del Río, J; Madroñero, R1
Kobayakawa, T1
Endoh, M; Taira, N; Yanagisawa, T1
Sasaki, T; Satoh, M; Shimura, S; Shirato, K; Takishima, T; Yamada, K1
Bowsher, RR; Cerimele, BJ; McNay, JL; Rowe, H; Schwertschlag, US1
Summers, RJ; Tan, YY1
Maekawa, M; Miyazaki, H; Murayama, T; Narita, H; Nomura, Y; Ono, S1
Berlan, M; Crampes, F; De Glisezinski, I; Galitzky, J; Lafontan, M; Moro, C; Sengenes, C; Thalamas, C1
Brown, JH; Chun, J; Means, CK; Miyamoto, S1
Bobrovová, Z; Haskova, P; Holeckova, M; Hrdina, R; Jansson, PJ; Kalinowski, DS; Mazurová, Y; Mladĕnka, P; Nachtigal, P; Palicka, V; Richardson, DR; Semecký, V; Simůnek, T; Vávrová, J1
Al-Attas, OS; Arya, DS; Bharti, S; Chauhan, SS; Hussain, T; Singh, R1
Guo, M; Hao, MH; Ma, XY; Sun, WP; Tang, Y; Zhu, HY1
Fu, F; Huang, Y; Lu, Y; Lv, H; Sha, C; Wang, T; Yu, F; Zhai, R; Zhang, L1
Ates, B; Colak, C; Ermis, N; Ozhan, O; Parlakpinar, H; Ulutas, Z; Vardi, N1
Arya, DS; Bhatia, J; Malik, S; Mutneja, E; Ray, R; Sahu, AK; Verma, VK1

Trials

2 trial(s) available for isoproterenol and thiophenes

ArticleYear
Effect of tibenelast (a phosphodiesterase inhibitor) and theophylline on isoproterenol-stimulated heart rate, cyclic AMP and norepinephrine levels.
    Pharmacology, 1993, Volume: 46, Issue:3

    Topics: Adult; Blood Pressure; Cyclic AMP; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; Norepinephrine; Phosphodiesterase Inhibitors; Regression Analysis; Theophylline; Thiophenes

1993
Atrial natriuretic peptide contributes to physiological control of lipid mobilization in humans.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:7

    Topics: Adipocytes; Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Atrial Natriuretic Factor; Blood Glucose; Cross-Over Studies; Cyclic GMP; Double-Blind Method; Epinephrine; Exercise; Exercise Test; Extracellular Fluid; Fatty Acids, Nonesterified; Glycerol; Guanylate Cyclase; Humans; Isoproterenol; Lipolysis; Male; Microdialysis; Norepinephrine; Oxygen Consumption; Phentolamine; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Receptors, Atrial Natriuretic Factor; Subcutaneous Tissue; Sympathetic Nervous System; Thiophenes

2004

Other Studies

22 other study(ies) available for isoproterenol and thiophenes

ArticleYear
A potentially antianginal benzo [b]thiophene with an amiodarone-like haemodynamic profile.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Angina Pectoris; Animals; Benzofurans; Blood Pressure; Cardiac Output; Coronary Circulation; Depression, Chemical; Dogs; Electrocardiography; Epinephrine; Female; Heart Rate; Hemodynamics; Hypertension; Isoproterenol; Male; Oxygen Consumption; Propylamines; Tachycardia; Thiophenes; Vascular Resistance

1975
Localization of (-)-[125I]cyanopindolol binding in guinea-pig heart: characteristics of non-beta-adrenoceptor related binding in cardiac pacemaker and conducting regions.
    Neuroscience letters, 1992, Feb-17, Volume: 136, Issue:1

    Topics: Alprenolol; Animals; Ascorbic Acid; Binding Sites; Ethanolamines; Female; Guinea Pigs; Haloperidol; Heart Conduction System; Isoproterenol; Male; Myocardium; Peroxidase; Phentolamine; Pindolol; Propanolamines; Propranolol; Protein Binding; Receptors, Adrenergic, beta; Serotonin; Thiophenes; Trachea

1992
Interaction of tertatolol at the "atypical" or beta 3-adrenoceptor in guinea-pig ileum.
    General pharmacology, 1992, Volume: 23, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Electric Stimulation; Ethanolamines; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Male; Methiothepin; Muscle Contraction; Muscle, Smooth; Propanolamines; Receptors, Adrenergic, beta; Thiophenes

1992
Antitachycardiac effect of OPC-8212, a novel cardiotonic agent, on tachycardiac responses of guinea pig isolated right atria to isoproterenol and histamine.
    Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:1

    Topics: Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Isoproterenol; Male; Nadolol; Pyrazines; Quinolines; Solvents; Tachycardia; Thiophenes

1987
Effects of tertatolol on post- and prejunctional beta adrenoceptors.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Blood Vessels; Dinoprost; Dogs; Dose-Response Relationship, Drug; Epinephrine; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Methoxyhydroxyphenylglycol; Norepinephrine; Potassium; Propanolamines; Prostaglandins F; Receptors, Adrenergic, beta; Thiophenes; Trachea

1985
Study of prejunctional beta-adrenoceptors in kidneys of normotensive and hypertensive rats using the new beta-adrenoceptor blocking drug tertatolol.
    American journal of nephrology, 1986, Volume: 6 Suppl 2

    Topics: Adrenergic beta-Antagonists; Animals; Hypertension; In Vitro Techniques; Isoproterenol; Kidney; Male; Norepinephrine; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Thiophenes

1986
Cardiotonic activity of a new inotropic agent, 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), in the dog with and without beta-blocker and Ca++-antagonist pretreatment.
    Japanese circulation journal, 1986, Volume: 50, Issue:1

    Topics: Animals; Benzazepines; Blood Pressure; Cardiac Output; Cardiotonic Agents; Diltiazem; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Isoproterenol; Pharmaceutical Vehicles; Pyrazines; Quinolines; Thiophenes

1986
N-substituted 2-amino-1-(2-thienyl)ethanols as beta-adrenergic blocking agents.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:8

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Ethanolamines; Guinea Pigs; Heart Rate; Histamine; Ileum; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Norepinephrine; Rats; Serotonin; Structure-Activity Relationship; Thiophenes; Vas Deferens

1973
Effects of anti-anaphylactic drugs upon passive cutaneous anaphylaxis mediated by graded doses of reaginic or non-reaginic antibodies in rats.
    International archives of allergy and applied immunology, 1974, Volume: 47, Issue:5

    Topics: Adrenergic beta-Agonists; Albumins; Albuterol; Amino Alcohols; Aminophylline; Animals; Chlorpheniramine; Cromolyn Sodium; Ethylenediamines; Immunoglobulin E; Isoproterenol; Methysergide; Passive Cutaneous Anaphylaxis; Pyridines; Rabbits; Reagins; Thiophenes; Tosyl Compounds

1974
Beta-adrenoreceptor blocking properties of new thienylethanolamine derivatives.
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:11

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Behavior, Animal; Blood Pressure; Cats; Epinephrine; Ethanolamines; Female; Guinea Pigs; Heart Rate; Histamine; In Vitro Techniques; Isoproterenol; Lethal Dose 50; Male; Mice; Propranolol; Rats; Receptors, Adrenergic; Refractory Period, Electrophysiological; Sleep; Thiophenes

1974
[Experimental study on drugs for the treatment of myocardial infarction].
    Japanese circulation journal, 1972, Volume: 36, Issue:1

    Topics: Angiography; Animals; Benzyl Compounds; Body Weight; Carboxylic Acids; Dipyridamole; Disease Models, Animal; Electrocardiography; Glycols; Hydrocortisone; Indomethacin; Isoproterenol; Male; Microradiography; Microscopy, Electron; Myocardial Infarction; Myocardium; Organ Size; Phenoxybenzamine; Phenylbutazone; Propranolol; Pyridines; Rats; Rats, Inbred Strains; Thiophenes

1972
Involvement of cyclic AMP in the positive inotropic effect of OPC-8212, a new cardiotonic agent, on the canine ventricular muscle.
    Japanese journal of pharmacology, 1984, Volume: 36, Issue:3

    Topics: Animals; Atenolol; Carbachol; Cardiotonic Agents; Cyclic AMP; Dogs; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Pyrazines; Quinolines; Stimulation, Chemical; Thiophenes

1984
An expectorant, stepronin, reduces airway secretion in vitro.
    Respiration; international review of thoracic diseases, 1994, Volume: 61, Issue:1

    Topics: Amiloride; Animals; Cats; Culture Techniques; Dogs; Dose-Response Relationship, Drug; Epithelium; Expectorants; Female; Glycine; Indomethacin; Isoproterenol; Male; Membrane Potentials; Mucus; Structure-Activity Relationship; Sulfides; Thiophenes; Trachea

1994
beta-Adrenoceptor regulation in rat heart, lung and skin after chronic treatment with (--)-tertatolol or (--)-propranolol.
    Journal of autonomic pharmacology, 1995, Volume: 15, Issue:6

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Female; Hemodynamics; Isoproterenol; Lung; Myocardium; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Skin; Thiophenes

1995
Effects of T-588, a novel cognitive enhancer, on ADP-ribosylation of G(s alpha) by cholera toxin and cyclic AMP accumulation in rat cerebral cortex.
    Neurochemistry international, 1999, Volume: 34, Issue:2

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Binding Sites; Catalysis; Cerebral Cortex; Cholera Toxin; Cyclic AMP; Diethylamines; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Nootropic Agents; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Thiophenes; Virulence Factors, Bordetella

1999
S1P1 receptor localization confers selectivity for Gi-mediated cAMP and contractile responses.
    The Journal of biological chemistry, 2008, May-02, Volume: 283, Issue:18

    Topics: Animals; beta-Cyclodextrins; Cyclic AMP; Enzyme Activation; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Isoproterenol; Lysophospholipids; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocardial Contraction; Myocytes, Cardiac; Oxadiazoles; Pertussis Toxin; Protein Transport; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; RNA, Messenger; Sphingosine; Thiophenes

2008
The novel iron chelator, 2-pyridylcarboxaldehyde 2-thiophenecarboxyl hydrazone, reduces catecholamine-mediated myocardial toxicity.
    Chemical research in toxicology, 2009, Volume: 22, Issue:1

    Topics: Animals; Catecholamines; Cell Line; Deferoxamine; Iron; Iron Chelating Agents; Isoproterenol; Male; Myocytes, Cardiac; Oxidation-Reduction; Rats; Rats, Wistar; Thiophenes

2009
Phosphorylation of Akt/GSK-3β/eNOS amplifies 5-HT2B receptor blockade mediated anti-hypertrophic effect in rats.
    FEBS letters, 2012, Jan-20, Volume: 586, Issue:2

    Topics: Animals; Cardiomegaly; Drug Evaluation, Preclinical; Drug Synergism; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Isoproterenol; Male; Maleimides; Myocardium; Nitric Oxide Synthase Type III; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Thiophenes

2012
Oltipraz attenuates the progression of heart failure in rats through inhibiting oxidative stress and inflammatory response.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:24

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Cytokines; Disease Models, Animal; Fibrosis; Heart Failure; Inflammation Mediators; Isoproterenol; Myocytes, Cardiac; Oxidative Stress; Pyrazines; Rats, Sprague-Dawley; Recovery of Function; Thiones; Thiophenes; Ventricular Function, Left; Ventricular Remodeling

2018
Effects of rotigotine and rotigotine extended-release microsphere therapy on myocardial ischemic injury in mice.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Jun-15, Volume: 134

    Topics: Animals; Cardiotonic Agents; Chlorpromazine; Creatine Kinase, MB Form; Dopamine Agonists; Isoproterenol; Male; Mice; Microspheres; Models, Animal; Myocardial Ischemia; Myocytes, Cardiac; Parkinson Disease; Tetrahydronaphthalenes; Thiophenes; Troponin I

2019
The Protective Effects of Compound 21 and Valsartan in Isoproterenol-Induced Myocardial Injury in Rats.
    Cardiovascular toxicology, 2021, Volume: 21, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Drug Therapy, Combination; Heart Failure; Heart Rate; Isoproterenol; Male; Myocardium; Rats, Wistar; Receptor, Angiotensin, Type 2; Stroke Volume; Sulfonamides; Thiophenes; Valsartan; Ventricular Function, Left

2021
Erdosteine salvages cardiac necrosis: Novel effect through modulation of MAPK and Nrf-2/HO-1 pathway.
    Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:12

    Topics: Animals; Biomarkers; Cardiomyopathies; Cytokines; Dose-Response Relationship, Drug; Heme Oxygenase (Decyclizing); Inflammation Mediators; Isoproterenol; Male; MAP Kinase Signaling System; Necrosis; NF-E2-Related Factor 2; Rats; Signal Transduction; Thioglycolates; Thiophenes

2020