isoproterenol has been researched along with sirolimus in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 10 (43.48) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Avison, MB; Denton, RM; Diggle, TA; Flynn, A; Foulstone, EJ; Moule, SK; Proud, CG | 1 |
| Burnett, P; Denton, RM; Diggle, TA; Edgell, NJ; McCormack, JG; Moule, SK; Rutter, GA | 1 |
| Denton, RM; Edgell, NJ; Foulstone, EJ; Moule, SK; Proud, CG; Welsh, GI | 1 |
| Diez, C; Hoppe, J; Piper, HM; Schlüter, K; Simm, A | 1 |
| Goldberg, Y; Piper, HM; Schlüter, KD; Taimor, G | 1 |
| DePinho, RA; Eisen, AM; Gallo, V; Ghiani, CA; Knutson, PL; McBain, CJ; Yuan, X | 1 |
| Araki, M; Fujita, M; Hasegawa, K; Iwai-Kanai, E; Kakita, T; Morimoto, T; Sasayama, S; Sawamura, T; Wada, H | 1 |
| Comellas, A; Guerrero, C; Pesce, L; Ridge, KM; Sznajder, JI | 1 |
| Claes, P; Grobben, B; Roymans, D; Slegers, H | 1 |
| Comellas, A; Pesce, L; Sznajder, JI | 1 |
| Adkins, JR; Castresana, MR; Newman, WH; Wang, Z | 1 |
| Acosta-Jaquez, HA; Fingar, DC; Soliman, GA | 1 |
| Connor, SA; Hoeffer, CA; Klann, E; Nguyen, PV | 1 |
| Cao, W; Chen, X; Chen, Y; Gao, Y; Liu, P; Yue, Z; Zeng, S; Zhang, L; Zou, J | 1 |
| Amri, EZ; Bengtsson, T; Chambard, JC; Dallner, OS; Hutchinson, DS; Olsen, JM; Pisani, DF; Sandström, AL; Sato, M | 1 |
| Dehpour, AR; Ejtemaei Mehr, S; Ghazi-Khansari, M; Mousavi, SE; Nobakht, M; Saeedi Saravi, SS | 1 |
| Chen, Z; Fan, XX; Gu, L; Guo, YB; Ji, GJ; Wang, SQ; Yang, HQ; Yuan, Q; Zhao, YT; Zhou, P | 1 |
| Guan, H; Han, X; Jin, F; Li, X; Qin, J; Shan, M; Wang, Y; Zhang, H; Zhang, J | 1 |
| Cao, YJ; Li, ZZ; Lin, ZR; Liu, PQ; Ye, JT; Yu, WJ | 1 |
1 review(s) available for isoproterenol and sirolimus
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
22 other study(ies) available for isoproterenol and sirolimus
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in response to insulin in rat epididymal fat-cells.
Topics: Adipocytes; Androstadienes; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Enzyme Inhibitors; Epidermal Growth Factor; Epididymis; Eukaryotic Initiation Factor-4E; Insulin; Intracellular Signaling Peptides and Proteins; Isoproterenol; Kinetics; Male; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Polyenes; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases; Sirolimus; Wortmannin | 1996 |
The hormonal regulation of pyruvate dehydrogenase complex.
Topics: Acetyl-CoA Carboxylase; Adipocytes; Androstadienes; Animals; Calcium; Energy Metabolism; Epinephrine; Hormones; Insulin; Isoproterenol; Lipid Metabolism; Mitochondria; Myocardium; Permeability; Phosphorylation; Polyenes; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Complex; Rats; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Wortmannin | 1996 |
Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms.
Topics: Adipocytes; Adrenergic beta-Agonists; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epididymis; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Insulin; Isoproterenol; Male; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Polyenes; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Sirolimus; Wortmannin | 1997 |
Activation of p70(S6) kinase by beta-adrenoceptor agonists on adult cardiomyocytes.
Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heart; Isoproterenol; Kinetics; Myocardium; Phenylalanine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Ribosomal Protein S6 Kinases; Sirolimus | 1998 |
Intracellular signaling leads to the hypertrophic effect of neuropeptide Y.
Topics: Androstadienes; Animals; Aprotinin; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cells, Cultured; Creatine Kinase; Cyclic AMP; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; GTP-Binding Proteins; Heart; Heart Ventricles; Isoenzymes; Isoproterenol; Male; Models, Cardiovascular; Myocardium; Neuropeptide Y; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Wortmannin | 1998 |
Voltage-activated K+ channels and membrane depolarization regulate accumulation of the cyclin-dependent kinase inhibitors p27(Kip1) and p21(CIP1) in glial progenitor cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Cycle Proteins; Cell Division; Cell Lineage; Cerebellum; Colforsin; Cyclin D; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Deferoxamine; Ion Channel Gating; Isoproterenol; Membrane Potentials; Mice; Microtubule-Associated Proteins; Oligodendroglia; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sirolimus; Stem Cells; Tetraethylammonium; Tumor Suppressor Proteins; Veratridine | 1999 |
Endothelin-1 as a protective factor against beta-adrenergic agonist-induced apoptosis in cardiac myocytes.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Anti-Bacterial Agents; Apoptosis; Azepines; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Flavonoids; Heart; Indoles; Isoproterenol; Myocardium; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sirolimus | 2000 |
beta-agonists regulate Na,K-ATPase via novel MAPK/ERK and rapamycin-sensitive pathways.
Topics: Adrenergic beta-Agonists; Animals; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Isoproterenol; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Propranolol; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sirolimus; Sodium-Potassium-Exchanging ATPase | 2000 |
Protein tyrosine kinase-dependent regulation of adenylate cyclase and phosphatidylinositol 3-kinase activates the expression of glial fibrillary acidic protein upon induction of differentiation in rat c6 glioma.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Androstadienes; Animals; Anti-Bacterial Agents; Benzoquinones; Cell Differentiation; Chromones; Cyclic AMP; Enzyme Inhibitors; Flavonoids; Gene Expression; Glial Fibrillary Acidic Protein; Glioma; Indoles; Isoproterenol; Isoquinolines; Lactams, Macrocyclic; Maleimides; Morpholines; Phosphatidylinositol 3-Kinases; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Sirolimus; Sulfonamides; Tumor Cells, Cultured; Wortmannin | 2001 |
Beta-adrenergic agonists regulate Na-K-ATPase via p70S6k.
Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Enzyme Activation; ErbB Receptors; Isoproterenol; Male; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinases; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Sodium-Potassium-Exchanging ATPase; TOR Serine-Threonine Kinases | 2003 |
Rapamycin inhibits release of tumor necrosis factor-alpha from human vascular smooth muscle cells.
Topics: Analysis of Variance; Anti-Bacterial Agents; Causality; Cell Division; Cell Movement; Cells, Cultured; Coated Materials, Biocompatible; Coronary Disease; Cyclic AMP; Drug Evaluation, Preclinical; Graft Occlusion, Vascular; Humans; Immunosuppressive Agents; Inflammation; Isoproterenol; Lipopolysaccharides; Muscle, Smooth, Vascular; Saphenous Vein; Sirolimus; Stents; Tumor Necrosis Factor-alpha; Tunica Intima | 2004 |
mTORC1 inhibition via rapamycin promotes triacylglycerol lipolysis and release of free fatty acids in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adrenergic beta-2 Receptor Agonists; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Fatty Acids, Nonesterified; Isoproterenol; Lipolysis; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Phosphorylation; Proteins; Sirolimus; TOR Serine-Threonine Kinases; Triglycerides | 2010 |
Fragile X mental retardation protein regulates heterosynaptic plasticity in the hippocampus.
Topics: Adrenergic beta-Agonists; Animals; Bicuculline; Biophysics; Dose-Response Relationship, Drug; Electric Stimulation; Emetine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Flavonoids; Fragile X Mental Retardation Protein; GABA-A Receptor Antagonists; Hippocampus; Immunosuppressive Agents; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Pyridines; rap GTP-Binding Proteins; Sirolimus; Time Factors | 2011 |
Rapamycin attenuated cardiac hypertrophy induced by isoproterenol and maintained energy homeostasis via inhibiting NF-κB activation.
Topics: Animals; Blotting, Western; Cardiomegaly; Cells, Cultured; Energy Metabolism; Homeostasis; Isoproterenol; Male; Microscopy, Electron, Transmission; NF-kappa B; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Sirolimus | 2014 |
Glucose uptake in brown fat cells is dependent on mTOR complex 2-promoted GLUT1 translocation.
Topics: Adipocytes, Brown; Adrenergic beta-3 Receptor Agonists; Animals; Cells, Cultured; Female; Glucose; Glucose Transporter Type 1; Humans; Insulin; Isoproterenol; Male; Mechanistic Target of Rapamycin Complex 2; Mice; Morpholines; Multipotent Stem Cells; Multiprotein Complexes; Phosphorylation; Primary Cell Culture; Protein Processing, Post-Translational; Protein Transport; Pyrimidines; Receptors, Adrenergic, beta-3; Sirolimus; TOR Serine-Threonine Kinases | 2014 |
Contribution of mammalian target of rapamycin in the pathophysiology of cirrhotic cardiomyopathy.
Topics: Action Potentials; Animals; Carbon Tetrachloride; Cardiomyopathies; Cardiotonic Agents; Chemical and Drug Induced Liver Injury; Heart Rate; Isoproterenol; Liver Cirrhosis, Experimental; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Phosphorylation; Protein Kinase Inhibitors; Rats, Wistar; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Ventricular Function, Left | 2016 |
Sensitized signalling between L-type Ca2+ channels and ryanodine receptors in the absence or inhibition of FKBP12.6 in cardiomyocytes.
Topics: Animals; Arrhythmias, Cardiac; Calcium Channels, L-Type; Calcium Signaling; Genotype; Isoproterenol; Kinetics; Male; Membrane Potentials; Mice, Knockout; Microscopy, Confocal; Models, Molecular; Myocytes, Cardiac; Patch-Clamp Techniques; Phenotype; Protein Binding; Protein Interaction Domains and Motifs; Receptor Cross-Talk; Ryanodine Receptor Calcium Release Channel; Sirolimus; Stochastic Processes; Tacrolimus; Tacrolimus Binding Proteins | 2017 |
Autophagy suppresses isoprenaline-induced M2 macrophage polarization via the ROS/ERK and mTOR signaling pathway.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Autophagy; Cell Line, Tumor; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Isoproterenol; Lung Neoplasms; Mammary Neoplasms, Experimental; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; RAW 264.7 Cells; Reactive Oxygen Species; Sirolimus; STAT3 Transcription Factor; TOR Serine-Threonine Kinases; Tumor Microenvironment | 2017 |
GDH promotes isoprenaline-induced cardiac hypertrophy by activating mTOR signaling via elevation of α-ketoglutarate level.
Topics: Animals; Cardiomegaly; Glucose; Glutamate Dehydrogenase; Glutamates; Isoproterenol; Ketoglutaric Acids; Lipids; Myocytes, Cardiac; Rats; Ribosomal Protein S6 Kinases; Sirolimus; Sugar Alcohol Dehydrogenases; TOR Serine-Threonine Kinases | 2022 |