isoproterenol and simvastatin

isoproterenol has been researched along with simvastatin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's10 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Antzelevitch, C; Cordeiro, JM; Gianetti, B; Sicouri, S; Zygmunt, AC1
Clapp, KM; Ellsworth, ML; Sprague, RS; Stephenson, AH1
Al-Manee, RZ; Al-Oteibi, MM; Al-Rasheed, NM; Al-Shareef, SA; Hasan, IH; Mahmoud, AM; Mohamad, RA1
Gandhi, HP; Patel, SS; Rathod, SP; Trivedi, JI; Variya, BC1
Cao, Y; Chen, C; Li, Z; Qi, R; Tuerdi, N; Wang, Y; Xu, L; Zhang, Q; Zhu, B1

Reviews

1 review(s) available for isoproterenol and simvastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

11 other study(ies) available for isoproterenol and simvastatin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Antiarrhythmic effects of simvastatin in canine pulmonary vein sleeve preparations.
    Journal of the American College of Cardiology, 2011, Feb-22, Volume: 57, Issue:8

    Topics: Acetylcholine; Action Potentials; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Electrophysiologic Techniques, Cardiac; Isoproterenol; Membrane Potentials; Models, Animal; Muscle Cells; Pulmonary Veins; Random Allocation; Reference Values; Sensitivity and Specificity; Simvastatin

2011
Simvastatin and GGTI-2133, a geranylgeranyl transferase inhibitor, increase erythrocyte deformability but reduce low O(2) tension-induced ATP release.
    American journal of physiology. Heart and circulatory physiology, 2013, Mar-01, Volume: 304, Issue:5

    Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Adult; Alkyl and Aryl Transferases; Animals; Anticholesteremic Agents; Cholesterol; Erythrocyte Deformability; Erythrocytes; Female; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Isoproterenol; Leucine; Male; Middle Aged; Naphthalenes; Nitric Oxide Synthase Type III; Oxygen; Partial Pressure; Peptides; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Simvastatin; Wasp Venoms; Young Adult

2013
Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Biomarkers; Cardiomegaly; Creatine Kinase, MB Form; Cytoprotection; Disease Models, Animal; Fibrosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Isoproterenol; Janus Kinases; Lipids; Male; Myocytes, Cardiac; NF-kappa B; Phosphorylation; Rats, Wistar; Signal Transduction; Simvastatin; STAT3 Transcription Factor; Troponin I

2015
Comparative evaluation of HMG CoA reductase inhibitors in experimentally-induced myocardial necrosis: Biochemical, morphological and histological studies.
    European journal of pharmacology, 2015, Oct-05, Volume: 764

    Topics: Adenosine Triphosphatases; Animals; Atorvastatin; Blood Glucose; Cardiotonic Agents; Catalase; Cholesterol; Fatty Acids, Monounsaturated; Fluvastatin; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Isoproterenol; Male; Myocardial Infarction; Myocardium; Necrosis; Pravastatin; Rats, Wistar; Rosuvastatin Calcium; Simvastatin; Superoxide Dismutase; Triglycerides

2015
Preventive effects of simvastatin nanoliposome on isoproterenol-induced cardiac remodeling in mice.
    Nanomedicine : nanotechnology, biology, and medicine, 2016, Volume: 12, Issue:7

    Topics: Animals; Atrial Remodeling; Fibrosis; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoproterenol; Liposomes; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Simvastatin

2016