Compounds > isoproterenol

isoproterenol and serine

isoproterenol has been researched along with serine in 57 studies

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-19905 (8.77)18.7374
1990's15 (26.32)18.2507
2000's22 (38.60)29.6817
2010's15 (26.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chubb, J; Huxtable, R1
Day, R; Farnsworth, CL; Feig, LA; Hildebrandt, JD1
Cohen, P; Hardie, DG; Haystead, TA; Moore, F1
Jones, LR; Lindemann, JP; Simmerman, HK; Wegener, AD1
Candelore, MR; Dixon, RA; Hill, WS; Sigal, IS; Strader, CD1
Jaques, R; Rüegg, M1
Combettes, M; Ferre, P; Issad, T1
Arner, P; Blaak, E; Hoffstedt, J; Lönnqvist, F; Shimizu, M1
Ijzerman, AP; Krasel, C; Lohse, MJ; Wieland, K; Zuurmond, HM1
Adomeit, A; Boehmer, A; Boehmer, FD; Graness, A; Kovalenko, M; Liebmann, C; Nürnberg, B; Steinmetzer, T; Wetzker, R1
Chikvashvilli, D; Jing, J; Levin, G; Lotan, I; Peretz, T1
de Cingolani, GC; Mattiazzi, A; Mundiña-Weilenmann, C; Ortale, M; Vittone, L1
Aizman, O; Aizman, R; Aperia, A; Cheng, XJ; Fisone, G; Greengard, P; Levenson, R1
Benovic, JL; Loudon, RP1
Isogaya, M; Kikkawa, H; Kurose, H; Nagao, T1
Nelson, CS; Neve, KA; Wiens, BL1
Bartel, S; Hempel, P; Karczewski, P; Krause, EG; Kuschel, M; Schlegel, WP1
Bretscher, A; Cao, TT; Deacon, HW; Reczek, D; von Zastrow, M1
Kobayashi, H; Kurose, H; Nagao, T; Sato, T1
Chu, G; Kranias, EG; Lester, JW; Luo, W; Young, KB; Zhai, J1
Bartel, S; Karczewski, P; Krause, EG; Schlegel, WP; Vetter, D; Wallukat, G1
Greenberg, AS; Kraemer, FB; Muliro, K; Patel, S; Roth, RA; Shen, WJ; Souza, SC1
Kaasik, A; Minajeva, A; Ohisalo, J; Paju, K1
Chen, YL; Hsu, KS; Huang, CC; Lo, SW1
Chen, W; Cong, M; Exum, ST; Lefkowitz, RJ; Lin, FT; Shenoy, S1
Mattiazzi, A; Mundiña-Weilenmann, C; Said, M; Vittone, L1
Claing, A; Freeman, JL; Gonzalo, P; Lavergne, JP; Lefkowitz, RJ; Pitcher, JA; Reboud, JP1
Bauersachs, J; Burkhardt, M; Münzel, T; Schäfer, A; Smolenski, A; Vollkommer, T; Walter, U1
BOULLIN, DJ1
Bölck, B; Brixius, K; Mehlhorn, U; Schwinger, RH; Wollmer, A1
Chen, SR; Cheng, H; Jiang, MT; Lai, FA; Sutherland, C; Walsh, MP; Warltier, DC; Xiao, B; Yang, D; Zhao, M1
Chen, SR; Davidoff, AW; Mei, J; Obayashi, M; Stuyvers, BD; ter Keurs, HE; Xiao, B1
Hino, S; Kikuchi, A; Nakayama, KI; Tanji, C1
Ganesan, AN; Johns, DC; Maack, C; O'Rourke, B; Sidor, A1
Clark, RB; Dai, W; Friedman, J; Godines, V; Knoll, BJ; Millman, EE; Moore, RH; Tran, TM; Vaughan, DJ1
Allen, ML; Davare, MA; Hall, DD; Hell, JW; McKnight, GS; Shi, M; Weisenhaus, M1
Cai, S; Chen, K; Chen, SR; Cheng, H; Jiang, D; Jones, PP; Kong, H; Tian, X; Walsh, MP; Wang, X; Xiao, B; Xie, W; Zhang, L1
Kohr, MJ; Velayutham, M; Wang, H; Wheeler, DG; Ziolo, MT; Zweier, JL1
Chen, X; García-Rivas, G; Houser, SR; Kubo, H; MacDonnell, SM; Scherman, JA; Valdivia, H1
Mattiazzi, A; Mundiña-Weilenmann, C; Vittone, L1
Bers, DM; Huke, S1
Matsuyoshi, H; Nagai, Y; Nakajima-Takenaka, C; Nishiyama, A; Obata, K; Takaki, M; Tohne, K; Zhang, GX1
Abraham, WC; Connor, SA; Guévremont, D; Nguyen, PV; O'Dell, TJ; Tenorio, G; Williams, J1
Baker, JG; Edwards, PC; Leslie, AG; Moukhametzianov, R; Nehmé, R; Schertler, GF; Tate, CG; Warne, T1
Grant, SG; Indersmitten, T; Komiyama, NH; Moody, TD; O'Dell, TJ; Watabe, AM1
Arakawa, M; Chakraborty, R; Chelikani, P; Eilers, M; Reeves, PJ; Smith, SO; Upadhyaya, J1
Bouillet, E; Christ-Crain, M; Dembinski, K; Frey, DM; Grisouard, J; Keller, U; Müller, B; Peterli, R; Radimerski, T; Timper, K; Zulewski, H1
Janssen, PM; Roof, SR; Shannon, TR; Ziolo, MT1
Albert, PR; Dehpour, AR; Ghahremani, MH; Ghazi-Khansari, M; Ostad, SN; Rahimian, R; Seyedabadi, M1
Álvarez López, MJ; Catalucci, D; Kaliman, P; Llagostera, E; Párrizas, M; Ruiz-Lozano, P; Scimia, C1
Andersson, DC; Betzenhauser, MJ; Marks, AR; Reiken, S; Shiomi, T; Umanskaya, A1
Morello, S; Pinto, A; Popolo, A; Sorrentino, R1
Granata, R; Marleau, S; Mulumba, M; Ong, H1
Buonarati, OR; Catterall, WA; Chowdhury, D; Hell, JW; Hofmann, F; Lee, B; Matt, L; Nanou, E; Navedo, MF; Nieves-Cintrón, M; Nystoriak, MA; Patriarchi, T; Poomvanicha, M; Price, JL; Qian, H1
Ashcroft, AS; Avkiran, M; Bernardo, BC; Karaś, A; McMullen, JR; Molenaar, C; Ranieri, A; Weeks, KL1
Camors, E; Fernandez-Tenorio, M; Janicek, R; Niggli, E; Potenza, DM; Ramos-Mondragón, R; Valdivia, HH1
He, Y; Liu, C; Liu, X; Wang, J; Wang, L; Wang, T; Wu, X; Yuan, D; Zhang, C; Zheng, J; Zhou, Z1

Other Studies

57 other study(ies) available for isoproterenol and serine

ArticleYear
Taurine and isoproterenol toxicity.
    Proceedings of the Western Pharmacology Society, 1976, Volume: 19

    Topics: Animals; Cardiomegaly; Glycine; Isoproterenol; Male; Myocardium; Organ Size; Rats; Serine; Taurine; Time Factors

1976
A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors.
    Molecular and cellular biology, 1991, Volume: 11, Issue:10

    Topics: Adenylyl Cyclases; Animals; Asparagine; Binding Sites; Blotting, Northern; Cyclic AMP; Enzyme Activation; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Magnesium; Mice; Mutation; Oncogene Protein p21(ras); Serine; Tumor Cells, Cultured

1991
Roles of the AMP-activated and cyclic-AMP-dependent protein kinases in the adrenaline-induced inactivation of acetyl-CoA carboxylase in rat adipocytes.
    European journal of biochemistry, 1990, Jan-12, Volume: 187, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Acetyl-CoA Carboxylase; Adipose Tissue; Amino Acid Sequence; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Epinephrine; Isoproterenol; Kinetics; Ligases; Molecular Sequence Data; Phosphorylation; Protein Kinases; Rats; Serine

1990
Phospholamban phosphorylation in intact ventricles. Phosphorylation of serine 16 and threonine 17 in response to beta-adrenergic stimulation.
    The Journal of biological chemistry, 1989, Jul-05, Volume: 264, Issue:19

    Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Calcium-Binding Proteins; Female; Guinea Pigs; Heart Ventricles; Isoproterenol; Macromolecular Substances; Male; Molecular Sequence Data; Myocardium; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphothreonine; Receptors, Adrenergic, beta; Serine; Threonine; Trypsin

1989
Identification of two serine residues involved in agonist activation of the beta-adrenergic receptor.
    The Journal of biological chemistry, 1989, Aug-15, Volume: 264, Issue:23

    Topics: Adenylyl Cyclases; Alprenolol; Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Iodocyanopindolol; Isoproterenol; Kinetics; Ligands; Molecular Sequence Data; Mutation; Pindolol; Receptors, Adrenergic, beta; Serine; Structure-Activity Relationship

1989
Tribenoside as an inhibitor of chemically induced histamine release.
    Experientia, 1974, Apr-15, Volume: 30, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Benzyl Compounds; Citrates; Cromolyn Sodium; Diethylcarbamazine; Flufenamic Acid; Glucose; Glycosides; Histamine H1 Antagonists; Histamine Release; Isoproterenol; Lysine; Male; Mast Cells; Niacinamide; Nikethamide; Norepinephrine; p-Methoxy-N-methylphenethylamine; Phenylbutazone; Phloretin; Serine; Sodium; Sodium Salicylate; Theophylline

1974
Isoproterenol inhibits insulin-stimulated tyrosine phosphorylation of the insulin receptor without increasing its serine/threonine phosphorylation.
    European journal of biochemistry, 1995, Nov-15, Volume: 234, Issue:1

    Topics: Adenosine Triphosphate; Adipocytes; Adrenergic beta-Agonists; Animals; Cells, Cultured; Female; Hydrogen-Ion Concentration; Insulin; Insulin Antagonists; Isoproterenol; Peptide Mapping; Phosphorylation; Rats; Rats, Wistar; Receptor, Insulin; Serine; Threonine; Tyrosine

1995
Effects of several putative beta 3-adrenoceptor agonists on lipolysis in human omental adipocytes.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1996, Volume: 20, Issue:5

    Topics: Adipocytes; Adrenergic beta-Agonists; Catechols; Dioxoles; Ethanolamines; Glycerol; Humans; Isoproterenol; Lipolysis; Omentum; Propanolamines; Serine

1996
Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Aug-20, Volume: 93, Issue:17

    Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Alprenolol; Animals; Asparagine; Binding Sites; CHO Cells; Computer Simulation; Cricetinae; Humans; Isoproterenol; Metoprolol; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Propranolol; Receptors, Adrenergic, beta-2; Serine; Signal Transduction; Stereoisomerism

1996
Tyrosine phosphorylation of GSalpha and inhibition of bradykinin-induced activation of the cyclic AMP pathway in A431 cells by epidermal growth factor receptor.
    The Journal of biological chemistry, 1996, Dec-06, Volume: 271, Issue:49

    Topics: Adenylyl Cyclases; Bradykinin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Humans; Isoproterenol; Oncogene Proteins; Phosphorylation; Serine; Threonine; Tumor Cells, Cultured; Tyrosine

1996
Deletion of the N-terminus of a K+ channel brings about short-term modulation by cAMP and beta 1-adrenergic receptor activation.
    Journal of molecular neuroscience : MN, 1996,Winter, Volume: 7, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Isoproterenol; Macromolecular Substances; Membrane Potentials; Mutagenesis, Site-Directed; Oocytes; Potassium Channels; Receptors, Adrenergic, beta-1; Recombinant Proteins; Sequence Deletion; Serine; Thionucleotides; Xenopus laevis

1996
Immunodetection of phosphorylation sites gives new insights into the mechanisms underlying phospholamban phosphorylation in the intact heart.
    The Journal of biological chemistry, 1996, Dec-27, Volume: 271, Issue:52

    Topics: Adenosine Triphosphatases; Animals; Binding Sites; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Isoproterenol; Male; Myocardium; Okadaic Acid; Phosphorylation; Rats; Rats, Wistar; Serine; Threonine

1996
PKA-mediated phosphorylation and inhibition of Na(+)-K(+)-ATPase in response to beta-adrenergic hormone.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Alanine; Animals; Cell Line; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Macromolecular Substances; Mutagenesis, Site-Directed; Okadaic Acid; Phosphorylation; Point Mutation; Rats; Recombinant Proteins; Rubidium; Serine; Sodium-Potassium-Exchanging ATPase; Spodoptera; Sulfonamides; Transfection

1997
Altered activity of palmitoylation-deficient and isoprenylated forms of the G protein-coupled receptor kinase GRK6.
    The Journal of biological chemistry, 1997, Oct-24, Volume: 272, Issue:43

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Cattle; COS Cells; Cysteine; DNA Primers; Eye Proteins; G-Protein-Coupled Receptor Kinase 1; G-Protein-Coupled Receptor Kinases; GTP-Binding Proteins; Isoproterenol; Kinetics; Liposomes; Molecular Sequence Data; Mutagenesis, Site-Directed; Palmitic Acid; Phosphatidylcholines; Phosphorylation; Polymerase Chain Reaction; Protein Kinases; Protein Prenylation; Protein Serine-Threonine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, beta-2; Recombinant Proteins; Retina; Rhodopsin; Sequence Deletion; Serine; Transfection

1997
The role of the seventh transmembrane region in high affinity binding of a beta 2-selective agonist TA-2005.
    Molecular pharmacology, 1998, Volume: 53, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Alanine; Amphetamines; Animals; Binding Sites; Cell Membrane; COS Cells; Hydroxyquinolines; Isoproterenol; Kinetics; Mutagenesis, Site-Directed; Quinolones; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Serine; Substrate Specificity

1998
Contribution of serine residues to constitutive and agonist-induced signaling via the D2S dopamine receptor: evidence for multiple, agonist-specific active conformations.
    Molecular pharmacology, 1998, Volume: 54, Issue:2

    Topics: Animals; Cyclic AMP; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Mutagenesis; Oocytes; Potassium Channels; Protein Conformation; Rats; Receptors, Dopamine D2; Serine; Signal Transduction; Sulfur Radioisotopes; Tumor Cells, Cultured; Xenopus laevis

1998
Ser16 prevails over Thr17 phospholamban phosphorylation in the beta-adrenergic regulation of cardiac relaxation.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Calcimycin; Calcium; Calcium Channels; Calcium Channels, L-Type; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Ionophores; Isoproterenol; Myocardial Contraction; Myocardium; Organ Culture Techniques; Phosphorylation; Rats; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum; Serine; Threonine

1999
A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor.
    Nature, 1999, Sep-16, Volume: 401, Issue:6750

    Topics: Actins; Adrenergic beta-Agonists; Binding Sites; Biotinylation; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Line; Endocytosis; Endosomes; Humans; Isoproterenol; Lysosomes; Molecular Sequence Data; Phosphoproteins; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, beta-2; Recombinant Proteins; Serine; Sodium-Hydrogen Exchangers; Thiazoles; Thiazolidines

1999
Ser203 as well as Ser204 and Ser207 in fifth transmembrane domain of the human beta2-adrenoceptor contributes to agonist binding and receptor activation.
    British journal of pharmacology, 1999, Volume: 128, Issue:2

    Topics: Adrenergic alpha-Agonists; Alanine; Amino Acid Substitution; Animals; CHO Cells; Cricetinae; Humans; Isoproterenol; Kinetics; Mutation; Rats; Receptors, Adrenergic, alpha-2; Serine

1999
A single site (Ser16) phosphorylation in phospholamban is sufficient in mediating its maximal cardiac responses to beta -agonists.
    The Journal of biological chemistry, 2000, Dec-08, Volume: 275, Issue:49

    Topics: Amino Acid Substitution; Animals; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Heart; Isoproterenol; Kinetics; Mice; Mice, Knockout; Mice, Transgenic; Mutagenesis, Site-Directed; Mutation, Missense; Myocardium; Myosin Heavy Chains; Phosphorylation; Promoter Regions, Genetic; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine

2000
Phosphorylation of phospholamban at threonine-17 in the absence and presence of beta-adrenergic stimulation in neonatal rat cardiomyocytes.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:12

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Animals, Newborn; Blotting, Western; Calcium; Calcium Channel Agonists; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ionophores; Isoproterenol; Myocardium; Okadaic Acid; Phosphorylation; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum; Serine; Signal Transduction; Thapsigargin; Threonine; Time Factors

2000
Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway.
    The Journal of biological chemistry, 2001, Nov-30, Volume: 276, Issue:48

    Topics: 3T3 Cells; Animals; Binding Sites; Cell Differentiation; CHO Cells; Cricetinae; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Immunoblotting; Isoproterenol; Lipolysis; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphorylation; Plasmids; Serine; Signal Transduction; Sterol Esterase; Tamoxifen; Time Factors; Transfection

2001
Decreased expression of phospholamban is not associated with lower beta-adrenergic activation in rat atria.
    Molecular and cellular biochemistry, 2001, Volume: 223, Issue:1-2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atrial Function; Calcium; Calcium-Binding Proteins; Female; Heart Atria; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phosphorylation; Propranolol; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Serine; Threonine; Tissue Extracts; Ventricular Function

2001
Activation of cAMP-dependent protein kinase suppresses the presynaptic cannabinoid inhibition of glutamatergic transmission at corticostriatal synapses.
    Molecular pharmacology, 2002, Volume: 61, Issue:3

    Topics: Adrenergic Agonists; Animals; Benzoxazines; Calcium; Calcium Channel Blockers; Cannabinoids; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Enzyme Activation; Enzyme Activators; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Isoproterenol; Male; Morpholines; Naphthalenes; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Glutamate; Receptors, Presynaptic; Serine; Synapses

2002
Phosphorylation of beta-arrestin2 regulates its function in internalization of beta(2)-adrenergic receptors.
    Biochemistry, 2002, Aug-27, Volume: 41, Issue:34

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Arrestins; beta-Arrestins; Casein Kinase II; Cell Line; Clathrin; COS Cells; Down-Regulation; Endocytosis; Humans; Isoproterenol; Phosphorylation; Point Mutation; Protein Binding; Protein Serine-Threonine Kinases; Receptors, Adrenergic, beta-2; Serine; Threonine; Time Factors

2002
The relative relevance of phosphorylation of the Thr(17) residue of phospholamban is different at different levels of beta-adrenergic stimulation.
    Pflugers Archiv : European journal of physiology, 2002, Volume: 444, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Male; Myocardial Contraction; Myocardium; Phosphorus Radioisotopes; Phosphorylation; Rats; Rats, Wistar; Serine; Sulfonamides; Threonine

2002
Beta 2-adrenergic receptor stimulated, G protein-coupled receptor kinase 2 mediated, phosphorylation of ribosomal protein P2.
    Biochemistry, 2002, Oct-22, Volume: 41, Issue:42

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Amino Acid Sequence; Animals; beta-Adrenergic Receptor Kinases; Cell Line; Cyclic AMP-Dependent Protein Kinases; G-Protein-Coupled Receptor Kinase 2; Humans; Isoproterenol; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Subunits; Rats; Receptors, Adrenergic, beta-2; Recombinant Proteins; Ribosomal Proteins; Serine; Substrate Specificity

2002
Endothelium-dependent and -independent relaxation and VASP serines 157/239 phosphorylation by cyclic nucleotide-elevating vasodilators in rat aorta.
    Biochemical pharmacology, 2003, Feb-01, Volume: 65, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Bronchodilator Agents; Cell Adhesion Molecules; Colforsin; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Microfilament Proteins; Nitroprusside; Nucleotides, Cyclic; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Serine; Vasodilation; Vasodilator Agents

2003
Pharmacological responses of thiamine-deficient rat tissues.
    British journal of pharmacology and chemotherapy, 1963, Volume: 20

    Topics: Acetylcholine; Animals; Diaphragm; Epinephrine; Gallamine Triethiodide; Heart; Isoproterenol; Neuromuscular Junction; Norepinephrine; Phrenic Nerve; Physostigmine; Rats; Serine; Thiamine; Thiamine Deficiency; Tubocurarine

1963
Ser16-, but not Thr17-phosphorylation of phospholamban influences frequency-dependent force generation in human myocardium.
    Pflugers Archiv : European journal of physiology, 2003, Volume: 447, Issue:2

    Topics: Adrenergic beta-Agonists; Adult; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cardiac Output, Low; Cardiomyopathy, Dilated; Case-Control Studies; Female; Humans; Isoenzymes; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Myocardium; Phosphorylation; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Threonine

2003
Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure.
    Circulation research, 2005, Apr-29, Volume: 96, Issue:8

    Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Dogs; Heart Failure; Isoproterenol; Myocytes, Cardiac; Phosphorylation; Ryanodine Receptor Calcium Release Channel; Serine

2005
Spontaneous diastolic contractions and phosphorylation of the cardiac ryanodine receptor at serine-2808 in congestive heart failure in rat.
    Cardiovascular research, 2006, Volume: 69, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Diastole; Echocardiography; Heart Failure; Isoproterenol; Male; Metoprolol; Models, Animal; Myocardial Contraction; Phosphorylation; Rats; Rats, Inbred BN; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Serine; Tacrolimus

2006
Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination.
    Molecular and cellular biology, 2005, Volume: 25, Issue:20

    Topics: Alprostadil; Animals; Axin Protein; Base Sequence; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Binding Sites; Bucladesine; Cell Line; Cell Nucleus; Chlorocebus aethiops; COS Cells; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Drug Stability; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; In Vitro Techniques; Isoproterenol; L Cells; Mice; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Phosphorylation; Repressor Proteins; RNA Interference; Serine; Signal Transduction; TCF Transcription Factors; Transcription Factor 4; Ubiquitin

2005
Beta-adrenergic stimulation of L-type Ca2+ channels in cardiac myocytes requires the distal carboxyl terminus of alpha1C but not serine 1928.
    Circulation research, 2006, Feb-03, Volume: 98, Issue:2

    Topics: Animals; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinases; Guinea Pigs; Isoproterenol; Myocytes, Cardiac; Protein Subunits; Receptors, Adrenergic, beta; Serine

2006
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation.
    The Journal of biological chemistry, 2006, Mar-17, Volume: 281, Issue:11

    Topics: Adenylyl Cyclases; Alanine; Arrestins; Aspartic Acid; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins; Binding Sites; Blotting, Western; Cell Line; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Epinephrine; G-Protein-Coupled Receptor Kinase 1; Green Fluorescent Proteins; Humans; Isoproterenol; Kinetics; Mutation; Phosphorylation; Pindolol; Protein Structure, Tertiary; Protein Transport; Receptors, Adrenergic, beta-2; Serine; Time Factors; Transfection

2006
Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons.
    Biochemistry, 2007, Feb-13, Volume: 46, Issue:6

    Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Isoproterenol; Mice; Mice, Knockout; Microtubule-Associated Proteins; Neurons; Phosphorylation; Rats; Receptors, Adrenergic, beta-2; Serine; Signal Transduction

2007
Functional consequence of protein kinase A-dependent phosphorylation of the cardiac ryanodine receptor: sensitization of store overload-induced Ca2+ release.
    The Journal of biological chemistry, 2007, Oct-12, Volume: 282, Issue:41

    Topics: Animals; Calcium; Cell Line; Cyclic AMP-Dependent Protein Kinases; Heart Ventricles; Humans; Isoproterenol; Models, Biological; Mutation; Myocardium; Myocytes, Cardiac; Phosphorylation; Rats; Ryanodine Receptor Calcium Release Channel; Serine

2007
Targeting of phospholamban by peroxynitrite decreases beta-adrenergic stimulation in cardiomyocytes.
    Cardiovascular research, 2008, Jan-15, Volume: 77, Issue:2

    Topics: Animals; Calcium-Binding Proteins; Isoproterenol; Mice; Molsidomine; Myocardial Contraction; Myocytes, Cardiac; Peroxynitrous Acid; Phosphorylation; Protein Phosphatase 1; Protein Phosphatase 2; Receptors, Adrenergic, beta; Serine

2008
Adrenergic regulation of cardiac contractility does not involve phosphorylation of the cardiac ryanodine receptor at serine 2808.
    Circulation research, 2008, Apr-25, Volume: 102, Issue:8

    Topics: Amino Acid Substitution; Animals; Cyclic AMP-Dependent Protein Kinases; Electrophysiologic Techniques, Cardiac; Isoproterenol; Mice; Myocardial Contraction; Myocardium; Phosphorylation; Ryanodine Receptor Calcium Release Channel; Serine; Sympathetic Nervous System

2008
Ca2+-calmodulin-dependent protein kinase phosphorylation of ryanodine receptor may contribute to the beta-adrenergic regulation of myocardial contractility independently of increases in heart rate.
    Circulation research, 2008, Jul-03, Volume: 103, Issue:1

    Topics: Amino Acid Substitution; Animals; Cyclic AMP-Dependent Protein Kinases; Electrophysiologic Techniques, Cardiac; Isoproterenol; Mice; Myocardial Contraction; Myocardium; Phosphorylation; Ryanodine Receptor Calcium Release Channel; Serine; Sympathetic Nervous System

2008
Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes.
    Biochemical and biophysical research communications, 2008, Nov-07, Volume: 376, Issue:1

    Topics: Animals; Antibodies, Phospho-Specific; Base Sequence; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Isoproterenol; Myocytes, Cardiac; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphoserine; Rats; Ryanodine Receptor Calcium Release Channel; Serine

2008
Left ventricular function of isoproterenol-induced hypertrophied rat hearts perfused with blood: mechanical work and energetics.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Blotting, Western; Calcium-Binding Proteins; Cardiomegaly; Collagen Type I; Collagen Type III; Coronary Circulation; Disease Models, Animal; Energy Metabolism; Heart Rate; Infusion Pumps, Implantable; Isoproterenol; Male; Membrane Proteins; Myocardial Contraction; Myocardium; Oxygen Consumption; Perfusion; Phosphoproteins; Phosphorylation; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Time Factors; Ventricular Function, Left; Ventricular Pressure

2009
'Silent' priming of translation-dependent LTP by ß-adrenergic receptors involves phosphorylation and recruitment of AMPA receptors.
    Learning & memory (Cold Spring Harbor, N.Y.), 2010, Volume: 17, Issue:12

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Biophysics; Carbazoles; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Phosphorylation; Propranolol; Pyrroles; Receptors, Adrenergic, beta; Receptors, AMPA; Serine

2010
The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor.
    Nature, 2011, Jan-13, Volume: 469, Issue:7329

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Albuterol; Amphetamines; Animals; Binding Sites; Catecholamines; Crystallography, X-Ray; Dobutamine; Drug Design; Drug Partial Agonism; Hydrogen Bonding; Hydroxyquinolines; Isoproterenol; Ligands; Models, Molecular; Protein Conformation; Protein Stability; Receptors, Adrenergic, beta-1; Serine; Structure-Activity Relationship; Turkeys

2011
Beta-adrenergic receptor activation rescues theta frequency stimulation-induced LTP deficits in mice expressing C-terminally truncated NMDA receptor GluN2A subunits.
    Learning & memory (Cold Spring Harbor, N.Y.), 2011, Volume: 18, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Biophysical Phenomena; Electric Stimulation; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Mice; Mitogen-Activated Protein Kinase 1; Mutation; N-Methylaspartate; Patch-Clamp Techniques; Peptide Fragments; Phosphorylation; Pyramidal Cells; Receptors, Adrenergic, beta; Receptors, N-Methyl-D-Aspartate; Serine

2011
Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β(2)-adrenergic receptor.
    Biochimica et biophysica acta, 2011, Volume: 1808, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino Acid Substitution; Amino Acids; Animals; Binding Sites; Chlorocebus aethiops; COS Cells; Cricetinae; Cyclic AMP; Dihydroalprenolol; Glycine; HEK293 Cells; Humans; Hydrogen Bonding; Isoproterenol; Models, Molecular; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Radioligand Assay; Receptors, Adrenergic, beta-2; Serine; Structure-Activity Relationship

2011
Metformin counters both lipolytic/inflammatory agents-decreased hormone sensitive lipase phosphorylation at Ser-554 and -induced lipolysis in human adipocytes.
    Archives of physiology and biochemistry, 2011, Volume: 117, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adult; Aged; Colforsin; Female; Humans; Hypoglycemic Agents; Inflammation; Interleukin-1beta; Isoproterenol; Lipolysis; Lipopolysaccharides; Male; Metformin; Middle Aged; Phosphorylation; Primary Cell Culture; Serine; Sterol Esterase; Tumor Necrosis Factor-alpha

2011
Effects of increased systolic Ca²⁺ and phospholamban phosphorylation during β-adrenergic stimulation on Ca²⁺ transient kinetics in cardiac myocytes.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:4

    Topics: Adenosine Triphosphatases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Benzylamines; Blotting, Western; Calcium; Calcium Signaling; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Enzyme Activation; In Vitro Techniques; Isoproterenol; Kinetics; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Phosphorylation; Sarcoplasmic Reticulum; Serine; Sulfonamides

2011
Ser/ Thr residues at α3/β5 loop of Gαs are important in morphine-induced adenylyl cyclase sensitization but not mitogen-activated protein kinase phosphorylation.
    The FEBS journal, 2012, Volume: 279, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Analgesics, Opioid; Animals; Blotting, Western; Cell Line, Tumor; Cyclic AMP; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gs; Immunoprecipitation; Isoproterenol; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morphine; Mutation; Phosphorylation; Protein Binding; Receptors, Adrenergic, beta-2; Receptors, Opioid, mu; Serine; Threonine; Transfection

2012
Altered β-adrenergic response in mice lacking myotonic dystrophy protein kinase.
    Muscle & nerve, 2012, Volume: 45, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Cell Membrane; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Isoproterenol; Mice; Mice, Knockout; Myocardium; Myotonic Dystrophy; Myotonin-Protein Kinase; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Adrenergic, beta; Serine; Sodium-Potassium-Exchanging ATPase; Vesicular Transport Proteins

2012
Stress-induced increase in skeletal muscle force requires protein kinase A phosphorylation of the ryanodine receptor.
    The Journal of physiology, 2012, Dec-15, Volume: 590, Issue:24

    Topics: Adrenergic beta-Agonists; Animals; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; Isoproterenol; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle Strength; Phosphorylation; Point Mutation; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Serine; Time Factors

2012
Antiadrenergic effect of adenosine involves connexin 43 turn-over in H9c2 cells.
    European journal of pharmacology, 2013, Sep-05, Volume: 715, Issue:1-3

    Topics: Adenosine; Adrenergic Antagonists; Animals; Cell Line; Connexin 43; Enzyme Activation; Gene Expression Regulation; Isoproterenol; Phosphorylation; Proteasome Endopeptidase Complex; Protein Kinase C; Proteolysis; Rats; Receptor, Adenosine A1; Serine; Ubiquitin; Ubiquitination

2013
QRFP-43 inhibits lipolysis by preventing ligand-induced complex formation between perilipin A, caveolin-1, the catalytic subunit of protein kinase and hormone-sensitive lipase in 3T3-L1 adipocytes.
    Biochimica et biophysica acta, 2015, Volume: 1851, Issue:5

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Carrier Proteins; Caveolin 1; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Enzyme Activation; Intercellular Signaling Peptides and Proteins; Isoproterenol; Lipid Droplets; Lipolysis; Mice; Multiprotein Complexes; Peptides; Perilipin-1; Phosphodiesterase 3 Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Transport; Receptors, G-Protein-Coupled; Serine; Signal Transduction; src-Family Kinases; Sterol Esterase; Tetradecanoylphorbol Acetate

2015
Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the β2-adrenergic receptor in neurons.
    Science signaling, 2017, 01-24, Volume: 10, Issue:463

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium Channels, L-Type; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Female; Imidazoles; Isoproterenol; Long-Term Potentiation; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Myocytes, Cardiac; Neuronal Plasticity; Neurons; Phosphorylation; Propanolamines; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Serine; Signal Transduction

2017
β-Adrenergic Stimulation Induces Histone Deacetylase 5 (HDAC5) Nuclear Accumulation in Cardiomyocytes by B55α-PP2A-Mediated Dephosphorylation.
    Journal of the American Heart Association, 2017, Mar-25, Volume: 6, Issue:4

    Topics: Active Transport, Cell Nucleus; Adrenergic beta-Agonists; Animals; Cell Nucleus; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Histone Deacetylases; Isoproterenol; Male; Mutation; Myocytes, Cardiac; Phosphorylation; Protein Binding; Protein Phosphatase 2; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, beta-1; RNA Interference; Serine; Signal Transduction; Time Factors; Transfection

2017
Phosphorylation of the ryanodine receptor 2 at serine 2030 is required for a complete β-adrenergic response.
    The Journal of general physiology, 2019, 02-04, Volume: 151, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Calcium Signaling; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Excitation Contraction Coupling; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Phosphorylation; Ryanodine Receptor Calcium Release Channel; Serine

2019
Chikusetsu saponin IVa attenuates isoprenaline-induced myocardial fibrosis in mice through activation autophagy mediated by AMPK/mTOR/ULK1 signaling.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 58

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Cardiomyopathies; Fibrosis; Heart; Isoproterenol; Mice, Inbred BALB C; Myocardium; Myocytes, Cardiac; Oleanolic Acid; Phosphorylation; Saponins; Serine; Signal Transduction; TOR Serine-Threonine Kinases

2019