isoproterenol has been researched along with quinazolines in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (38.30) | 18.7374 |
| 1990's | 14 (29.79) | 18.2507 |
| 2000's | 8 (17.02) | 29.6817 |
| 2010's | 7 (14.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gogerty, JH; Hardtmann, GE; Iorio, LC; Koletar, G; Pfister, OR | 1 |
| Jackson, G; Jackson, PG; Jewitt, DE; Kitson, D | 1 |
| Jackson, PG; Jennings, K; Jewitt, D | 1 |
| Graham, RM; Oates, HF; Stoker, LM; Stokes, GS | 1 |
| Ebbert, M; Janssens, WJ; Leidig, A; Meuter, C; Peters, T; Wilffert, B; Wilhelm, D | 1 |
| Amano, M; Kanamori, T; Kinoshita, M; Shichiri, G; Takahashi, M | 1 |
| Beck, E; Conrad, C; de Chaffoy de Courcelles, D; Heers, C; Peters, T; Schneider, J; Wilffert, B | 1 |
| Chiba, S; Matsuura, M; Zenda, H | 1 |
| Behnke, N; Müller, W; Neumann, J; Schmitz, W; Scholz, H; Stein, B | 1 |
| Decker, N; Grima, M; Schwartz, J | 1 |
| Evdokimov, EI; Stets, VR; Tishkin, VS | 1 |
| Akimoto, Y; Fujiwara, M; Kurahashi, K; Sono, K | 1 |
| Goto, K; Ishikawa, T; Kimura, S; Masaki, T; Yanagisawa, M | 1 |
| Sonoki, H; Sugimoto, T; Tomaru, T; Uchida, Y | 1 |
| Parratt, JR; Winslow, E | 1 |
| Ishihara, Y; Kitamura, S; Kosaka, K; Yotsumoto, H | 1 |
| McCarthy, L; McMahon, KK; Schimmel, RJ | 1 |
| Curtis-Prior, PB; Tan, S | 1 |
| Bradley, L; Doggrell, SA | 1 |
| Corvera, S; García-Sáinz, JA; Pushpendran, CK | 1 |
| Asano, Y; Imai, M; Kusano, E; Nakamura, R | 1 |
| Blaschke, TF; Rubin, PC | 1 |
| Gerber, JG; Nies, AS; Olson, RD | 1 |
| Schmitz, W; Scholz, H; Seeland, C; Stein, B | 1 |
| Artigou, JY; Bors, V; Charniot, JC; Fournier, P; Gandjbakhch, I; Grosgogeat, Y; Lechat, P; Pavie, A; Salloum, J | 1 |
| Iwai, M; Shimazu, T | 1 |
| Dobson, JG; Fenton, RA; Sawmiller, DR | 1 |
| Barnes, PJ; Giembycz, MA; Kelly, JJ | 1 |
| Chowdhury, BK; Findsen, LA; Igarashi, N; Kong, B; Ojo, B | 1 |
| Nasa, Y; Takeo, S; Yabe, K | 1 |
| Deng, XF; Mulay, S; Varma, DR | 1 |
| Fukuchi, Y; Kira, S; Muramatsu, M; Ohnishi, M; Oka, M; Sato, K | 1 |
| Daaka, Y; Lefkowitz, RJ; Luttrell, LM; Maudsley, S; Pierce, KL | 1 |
| Potter, DE; Thompson, WJ; Zhou, L | 1 |
| Chen, F; Ireland, ME; Mrock, LK | 1 |
| Eckhart, AD; Eguchi, S; Kim, J; Koch, WJ | 1 |
| Chen, Z; Rola-Pleszczynski, M; Stankova, J | 1 |
| Slomiany, A; Slomiany, BL | 1 |
| Bartha, E; Czopf, L; Deres, P; Halmosi, R; Hantó, K; Hideg, K; Kálai, T; Kulcsár, G; Pálfi, A; Sümegi, B; Szabados, E; Tóth, A; Tóth, K | 1 |
| Deres, P; Gallyas, F; Halmosi, R; Hanto, K; Hideg, K; Kalai, T; Kulcsar, G; Palfi, A; Sumegi, B; Szabados, E; Szereday, Z; Toth, A; Toth, K | 1 |
| Deng, HW; Hu, CP; Li, JZ; Li, XH; Li, YJ; Liao, MC; Peng, J; Xiao, L; Zhang, YS | 1 |
| Gerl, M; Höcherl, K; Schweda, F | 1 |
| Bedja, D; Belmonte, F; Gabrielson, K; Guo, X; Kang, B; Pin, S; Sysa-Shah, P; Tsuchiya, N; Xu, Y | 1 |
| Carter, RL; Grisanti, LA; Houser, SR; Makarewich, CA; Radcliffe, SW; Repas, AA; Talarico, JA; Tang, HA; Tilley, DG; Yu, JE | 1 |
| Carter, RL; Grisanti, LA; Repas, AA; Talarico, JA; Tilley, DG; Yu, JE | 1 |
| Carter, RL; Gold, JI; Grisanti, LA; Koch, WJ; Repas, AA; Talarico, JA; Tilley, DG | 1 |
| Hoang, P; Jacquir, S; Lemus, S; Ma, Z | 1 |
47 other study(ies) available for isoproterenol and quinazolines
| Article | Year |
|---|---|
Synthesis and biological evaluation of some 10-substituted 2,3-dihydroimidazo[2,1-b]quinazolin-5(10H)-ones, a new class of bronchodilators.
Topics: Animals; Bronchodilator Agents; Dogs; Female; Guinea Pigs; Hemodynamics; Histamine; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Isoproterenol; Lethal Dose 50; Male; Mice; Muscle Contraction; Muscle, Smooth; Ovalbumin; Passive Cutaneous Anaphylaxis; Quinazolines; Structure-Activity Relationship; Theophylline; Trachea | 1975 |
The inotropic effects of UK 14,275, a phosphodiesterase inhibitor, in man.
Topics: Adult; Drug Interactions; Humans; Isoproterenol; Male; Myocardial Contraction; Phosphodiesterase Inhibitors; Piperidines; Propranolol; Quinazolines; Stimulation, Chemical | 1978 |
Efficacy of new inotropic drugs in clinical coronary heart failure.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Catecholamines; Dobutamine; Heart Failure; Heart Rate; Hemodynamics; Humans; Infusions, Parenteral; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Phonocardiography; Phosphodiesterase Inhibitors; Piperidines; Pressure; Quinazolines; Vascular Resistance | 1978 |
Haemodynamic effects of prazosin.
Topics: Animals; Atropine; Blood Cell Count; Blood Pressure; Diazoxide; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Hemodynamics; Isoproterenol; Pentolinium Tartrate; Prazosin; Quinazolines; Rats; Renin; Timolol | 1976 |
In vitro pharmacology of R 80122, a novel phosphodiesterase inhibitor.
Topics: Action Potentials; Animals; Benzimidazoles; Carbachol; Female; Guinea Pigs; Heart Rate; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Milrinone; Myocardial Contraction; Norepinephrine; Ouabain; Oxindoles; Papillary Muscles; Phosphodiesterase Inhibitors; Pyridones; Quinazolines; Stimulation, Chemical; Vasodilator Agents | 1992 |
Increased uncoupling of beta-, beta 1- and beta 2-adrenoceptor to myocardial contraction in failing human myocardium.
Topics: Adult; Aged; Binding, Competitive; Dobutamine; Down-Regulation; Female; Heart Failure; Humans; Iodocyanopindolol; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Pindolol; Quinazolines; Receptors, Adrenergic, beta; Terbutaline | 1992 |
Cardiac effects of R 79595 and its isomers (R 80122 and R 80123) in an acute heart failure model. A new class of cardiotonic agents with highly selective phosphodiesterase III inhibitory properties.
Topics: Animals; Cardiac Output; Cardiac Output, Low; Cardiotonic Agents; Female; Guinea Pigs; Heart; Heart Rate; Heart Ventricles; Hexobarbital; Imidazoles; In Vitro Techniques; Isoenzymes; Isoproterenol; Male; Phosphodiesterase Inhibitors; Quinazolines | 1992 |
Pharmacologic analysis of 7-O-ethyl-fangchinoline-induced vasodilation properties in isolated perfused common carotid arteries of Wistar Kyoto rats and spontaneously hypertensive rats.
Topics: Alkaloids; Animals; Atropine; Benzylisoquinolines; Carotid Arteries; Diltiazem; In Vitro Techniques; Isoproterenol; Male; Phenylephrine; Propranolol; Quinazolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Vasodilation; Vasodilator Agents | 1991 |
Differential antagonism by 1,3-dipropylxanthine-8-cyclopentylxanthine and 9-chloro-2-(2-furanyl)-5,6-dihydro-1,2,4-triazolo(1,5-c)quinazolin-5-im ine of the effects of adenosine derivatives in the presence of isoprenaline on contractile response and cycli
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cyclic AMP; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Heart; Isoproterenol; Male; Myocardial Contraction; Quinazolines; Receptors, Purinergic; Triazoles; Vasodilator Agents; Xanthines | 1990 |
Inhibition of some new cardiotonic agents by tetrodotoxin.
Topics: Animals; Cardiotonic Agents; Dihydropyridines; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Imidazoles; In Vitro Techniques; Ion Channels; Isoproterenol; Milrinone; Myocardial Contraction; Protoveratrines; Pyridines; Pyridones; Quinazolines; Tetrodotoxin | 1986 |
[The efficacy of quinazopyrine, preparation E and riboxin in experimental myocardial infarct].
Topics: Animals; Cardiovascular Agents; Drug Evaluation, Preclinical; Heart; Inosine Diphosphate; Inosine Nucleotides; Isoproterenol; Male; Myocardial Infarction; Myocardium; Pituitary Hormones, Posterior; Quinazolines; Rats; Rats, Inbred Strains | 1989 |
Effects of specific alpha-adrenoceptive agents on extraneuronal uptake (uptake2) of isoproterenol in perfused rat heart.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Guanabenz; Isoproterenol; Male; Methoxamine; Myocardium; Neurons; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Sulfonamides; Tropolone | 1989 |
Positive inotropic action of novel vasoconstrictor peptide endothelin on guinea pig atria.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Atenolol; Atrial Function; Calcium; Cimetidine; Diphenhydramine; Endothelins; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Methysergide; Myocardial Contraction; Nicardipine; Peptides; Potassium; Quinazolines; Reference Values | 1988 |
[Effects of prazosin, SGB-1534, dobutamine and isoproterenol on congestive heart failure in dogs].
Topics: Adrenergic alpha-Antagonists; Animals; Disease Models, Animal; Dobutamine; Dogs; Heart Failure; Hemodynamics; Isoproterenol; Prazosin; Quinazolines | 1988 |
Cardiovascular pharmacology of quazodine (MJ-1988), with particular reference to effects of myocardial blood flow and metabolic heat production.
Topics: Adrenergic beta-Antagonists; Amino Alcohols; Animals; Aorta; Arrhythmias, Cardiac; Blood Pressure; Blood Vessels; Cardiac Output; Cats; Coronary Vessels; Depression, Chemical; Dilatation; Electrocardiography; Heart; Heart Rate; Heart Ventricles; Isoproterenol; Liver Circulation; Muscle Contraction; Myocardium; Oxygen Consumption; Quinazolines; Regional Blood Flow; Thermometers; Vascular Resistance | 1971 |
The potentiating effect of an alpha-adrenergic blocking agent (E-643) on the action of bronchodilators.
Topics: Adrenergic alpha-Antagonists; Animals; Bronchodilator Agents; Cyclic AMP; Cyclic GMP; Drug Synergism; Epinephrine; Guinea Pigs; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Prostaglandins E; Quinazolines; Trachea | 1980 |
Alpha 1-adrenergic stimulation of hamster brown adipocyte respiration.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue, Brown; Animals; Clonidine; Cricetinae; Isoproterenol; Kinetics; Male; Mesocricetus; Methoxamine; Norepinephrine; Oxygen Consumption; Phenylephrine; Prazosin; Propranolol; Quinazolines; Receptors, Adrenergic, alpha | 1983 |
Anti-lipolytic action of prazosin in hamster fat cells.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Bucladesine; Cricetinae; Epididymis; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Norepinephrine; Prazosin; Quinazolines; Yohimbine | 1984 |
Effects of prazosin, phentolamine and yohimbine on noradrenergic transmission in the rat right ventricle in vitro.
Topics: Animals; Electric Stimulation; Heart; Isoproterenol; Male; Myocardial Contraction; Norepinephrine; Phentolamine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Synaptic Transmission; Yohimbine | 1983 |
Effect of pertussis toxin on hormonal responsiveness of rat hepatocytes.
Topics: Adenylate Cyclase Toxin; Animals; Bacterial Toxins; Cyclic AMP; Epinephrine; Female; Glucagon; In Vitro Techniques; Isoproterenol; Kinetics; Liver; Pertussis Toxin; Phosphatidylinositols; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Urea; Virulence Factors, Bordetella | 1983 |
Distribution of alpha-adrenergic receptors in the rabbit nephron.
Topics: Animals; Atenolol; Female; Isoproterenol; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Norepinephrine; Phenoxybenzamine; Prazosin; Quinazolines; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha; Tissue Distribution | 1984 |
Studies on the clinical pharmacology of prazosin. I: Cardiovascular, catecholamine and endocrine changes following a single dose.
Topics: Adult; Blood Pressure; Catecholamines; Drug Interactions; Endocrine Glands; Growth Hormone; Heart Rate; Hemodynamics; Humans; Hydrocortisone; Isoproterenol; Male; Prazosin; Prolactin; Quinazolines; Renin | 1980 |
Prazosin does not alter canine renin release in response to systemic hypotension or intrarenal isoprenaline and prostaglandin I2 infusion.
Topics: Animals; Dogs; Epoprostenol; Hemodynamics; Hypotension; Infusions, Parenteral; Isoproterenol; Kidney; Natriuresis; Prazosin; Prostaglandins; Quinazolines; Renin | 1980 |
Pharmacological characterization of A2-adenosine receptors in guinea-pig ventricular cardiomyocytes.
Topics: Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cells, Cultured; Cyclic AMP; Drug Interactions; Female; Guinea Pigs; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Pertussis Toxin; Phenethylamines; Quinazolines; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Signal Transduction; Triazoles; Virulence Factors, Bordetella; Xanthines | 1994 |
[Evaluation of a new cardiotonic agent on human isolated atrium].
Topics: Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Drug Evaluation; Guinea Pigs; Heart Atria; Humans; Isoproterenol; Pyridazines; Quinazolines | 1993 |
Exaggeration of acute liver damage by hepatic sympathetic nerves and circulating catecholamines in perfused liver of rats treated with D-galactosamine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Aspartate Aminotransferases; Calcium; Electric Stimulation; Galactosamine; Isoproterenol; L-Lactate Dehydrogenase; Liver; Male; Norepinephrine; Perfusion; Phenylephrine; Quinazolines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Sympathomimetics | 1996 |
Myocardial adenosine A1 and A2 receptor activities during juvenile and adult stages of development.
Topics: Adenosine; Aging; Animals; Coronary Vessels; Drug Synergism; Heart; Isoproterenol; Male; Myocardial Contraction; Myocardium; Osmolar Concentration; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Triazoles; Veins; Xanthines | 1996 |
Phosphodiesterase 4 in macrophages: relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Binding Sites; Brain; Chromatography, Ion Exchange; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Isoenzymes; Isoproterenol; Kinetics; Macrophages, Peritoneal; Male; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Quinazolines; Rats; Regression Analysis; Rolipram; Stereoisomerism; Thiazoles; Tritium | 1996 |
Synthesis and bronchodilatory activity of four new derivatives of deoxyvasicine.
Topics: Alkaloids; Aminophylline; Animals; Bronchial Spasm; Bronchodilator Agents; Drug Evaluation, Preclinical; Guinea Pigs; In Vitro Techniques; Isoproterenol; Quinazolines; Structure-Activity Relationship; Trachea | 1996 |
Beta-adrenoceptor stimulation-mediated preconditioning-like cardioprotection in perfused rat hearts.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Creatine Kinase; Heart; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Norepinephrine; Phenylephrine; Quinazolines; Random Allocation; Rats; Rats, Sprague-Dawley; Timolol; Ventricular Function, Left | 1997 |
Role of Ca(2+)-independent PKC in alpha 1-adrenoceptor-mediated inotropic responses of neonatal rat hearts.
Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Calcium; Carbazoles; Diacylglycerol Kinase; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Heart Ventricles; In Vitro Techniques; Indoles; Inositol Phosphates; Isoenzymes; Isoproterenol; Maleimides; Methoxamine; Myocardial Contraction; Myocardium; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Protein Kinase C; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 1997 |
E4021, a selective phosphodiesterase 5 inhibitor, potentiates the vasodilator effect of inhaled nitric oxide in isolated perfused rat lungs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Inhalation; Animals; Bronchodilator Agents; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Hypertension, Pulmonary; In Vitro Techniques; Isoproterenol; Lung; Male; Nitric Oxide; Nitroprusside; Perfusion; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperidines; Pulmonary Circulation; Quinazolines; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation | 1999 |
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clathrin; COS Cells; Endocytosis; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Fluorescent Antibody Technique; GTP-Binding Proteins; Isoproterenol; Mitogen-Activated Protein Kinases; Phosphorylation; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cell Surface; Transfection; Tyrphostins | 2000 |
Functional identification of phosphodiesterase activity in human trabecular meshwork cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Cells, Cultured; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Humans; Isoproterenol; Nitroprusside; Piperidines; Quinazolines; Signal Transduction; Trabecular Meshwork | 2000 |
A role for endogenous TGFalpha and associated signaling pathways in the differentiation of lens fiber cells.
Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Chickens; Cyclic AMP; Enzyme Inhibitors; ErbB Receptors; Eye Proteins; Intermediate Filament Proteins; Isoproterenol; Lens, Crystalline; Mitogen-Activated Protein Kinase 1; Phosphorylation; Quinazolines; Receptor Cross-Talk; Signal Transduction; Transforming Growth Factor alpha | 2001 |
Beta-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases.
Topics: Androstadienes; Animals; Cells, Cultured; DNA Replication; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Fibroblasts; Heart; Isoproterenol; Male; Mitogen-Activated Protein Kinases; Myocardium; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tyrphostins; Virulence Factors, Bordetella; Wortmannin | 2002 |
Activation of ERK1/2 by platelet-activating factor receptor is independent of receptor internalisation and G-protein activation.
Topics: Animals; Arrestins; beta-Adrenergic Receptor Kinases; Blotting, Western; Cell Line; Chlorocebus aethiops; Clathrin-Coated Vesicles; Cloning, Molecular; COS Cells; Cyclic AMP-Dependent Protein Kinases; Dynamins; Endocytosis; ErbB Receptors; Humans; Isoproterenol; Leukotriene B4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Pertussis Toxin; Phosphorylation; Platelet Membrane Glycoproteins; Quinazolines; Receptors, G-Protein-Coupled; Signal Transduction; Sucrose; Transfection; Tyrphostins | 2003 |
Salivary phospholipid secretion in response to beta-adrenergic stimulation is mediated by Src kinase-dependent epidermal growth factor receptor transactivation.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Androstadienes; Animals; Bucladesine; Choline; Colforsin; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Isoproterenol; Phosphoinositide-3 Kinase Inhibitors; Phospholipids; Pyrimidines; Quinazolines; Rats; Receptors, Adrenergic, beta; Saliva; src-Family Kinases; Sublingual Gland; Transcriptional Activation; Wortmannin | 2004 |
The role of Akt and mitogen-activated protein kinase systems in the protective effect of poly(ADP-ribose) polymerase inhibition in Langendorff perfused and in isoproterenol-damaged rat hearts.
Topics: Animals; Energy Metabolism; Enzyme Inhibitors; Heart; Hydrogen Peroxide; Isoproterenol; Lipid Peroxidation; Male; Mitogen-Activated Protein Kinases; Myocardium; Perfusion; Phosphorylation; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Protective Agents; Proteins; Quinazolines; Rats; Rats, Sprague-Dawley | 2005 |
PARP inhibition prevents postinfarction myocardial remodeling and heart failure via the protein kinase C/glycogen synthase kinase-3beta pathway.
Topics: Animals; Cardiomegaly; Collagen Type III; Electrocardiography; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart Failure; Isoproterenol; Male; Mitogen-Activated Protein Kinases; Myocardial Infarction; Natriuretic Peptide, Brain; Phosphorylation; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Kinase C; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Ventricular Remodeling | 2006 |
Reversal of isoprenaline-induced cardiac remodeling by rutaecarpine via stimulation of calcitonin gene-related peptide production.
Topics: Animals; Apoptosis; Body Weight; Calcitonin Gene-Related Peptide; Echocardiography; Ganglia, Spinal; Heart Ventricles; In Situ Nick-End Labeling; Indole Alkaloids; Isoproterenol; Male; Myocytes, Cardiac; Organ Size; Quinazolines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Ventricular Remodeling | 2010 |
Proteinase-activated receptors 1 and 2 exert opposite effects on renal renin release.
Topics: Adrenergic beta-Agonists; Animals; Dose-Response Relationship, Drug; Isoproterenol; Juxtaglomerular Apparatus; Kidney; Male; Mice; Mice, Inbred C57BL; Models, Animal; Nitric Oxide; Oligopeptides; Pyrroles; Quinazolines; Receptor, PAR-1; Receptor, PAR-2; Renin; Thrombin | 2011 |
Cardiac-specific over-expression of epidermal growth factor receptor 2 (ErbB2) induces pro-survival pathways and hypertrophic cardiomyopathy in mice.
Topics: Animals; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Cell Survival; Electrophysiological Phenomena; Gene Expression; Isoproterenol; Lapatinib; Male; Mice; Mice, Transgenic; Myocytes, Cardiac; Organ Size; Organ Specificity; Protein Biosynthesis; Quinazolines; Rats; Receptor, ErbB-2; Signal Transduction | 2012 |
β-Adrenergic receptor-mediated transactivation of epidermal growth factor receptor decreases cardiomyocyte apoptosis through differential subcellular activation of ERK1/2 and Akt.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Apoptosis; Caspase 3; Cats; ErbB Receptors; Gene Expression Regulation; Isoproterenol; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Phosphorylation; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Tyrphostins | 2014 |
β-adrenergic receptor-dependent alterations in murine cardiac transcript expression are differentially regulated by gefitinib in vivo.
Topics: Adrenergic beta-Agonists; Animals; Down-Regulation; Female; Gefitinib; Gene Expression Profiling; Gene Regulatory Networks; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Receptors, Adrenergic, beta; Up-Regulation | 2014 |
Temporal and gefitinib-sensitive regulation of cardiac cytokine expression via chronic β-adrenergic receptor stimulation.
Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Cardiomegaly; Cells, Cultured; Chemokine CCL2; ErbB Receptors; Fibrosis; Gefitinib; Heart Ventricles; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Myofibroblasts; Quinazolines; RNA, Messenger; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2015 |
Quantification of Contractile Dynamic Complexities Exhibited by Human Stem Cell-Derived Cardiomyocytes Using Nonlinear Dimensional Analysis.
Topics: Cells, Cultured; Electric Stimulation; Flecainide; Humans; Induced Pluripotent Stem Cells; Isoproterenol; Kinetics; Myocardial Contraction; Myocytes, Cardiac; Quinazolines | 2019 |