isoproterenol has been researched along with pyrazines in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (33.33) | 18.7374 |
| 1990's | 21 (50.00) | 18.2507 |
| 2000's | 1 (2.38) | 29.6817 |
| 2010's | 5 (11.90) | 24.3611 |
| 2020's | 1 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Tomlinson, RW; Wood, AW | 1 |
| Das, AM; Harris, DA | 2 |
| Beleta, J; Berga, P; Bou, J; Cardelús, I; Fernández, AG; Gristwood, RW; Llenas, J | 1 |
| Doggrell, SA; Surman, AJ | 2 |
| Antunes-Rodrigues, J; Ramalho, MJ; Reis, LC | 1 |
| Lugnier, C; Muller, B; Stoclet, JC | 1 |
| Bailey, IA; Kemp, PR; Radda, GK; Seymour, AM | 1 |
| Barnette, MS; Grous, M; Ormsbee, HS; Torphy, TJ | 1 |
| Ishii, K; Taira, N; Yanagisawa, T | 1 |
| English, TA; Gristwood, RW; Owen, DA; Sampford, KA; Wallwork, J | 1 |
| Brown, AM; Imoto, Y; Schwartz, A; Yatani, A | 1 |
| Eden, RJ; Gristwood, RW; Owen, DA; Taylor, EM | 1 |
| Barrett, RJ; Harleman, JH; Joseph, EC | 1 |
| Hori, M; Inoue, M; Ito, H; Iwai, K; Kamada, T; Kitabatake, A; Kitakaze, M; Koretsune, Y; Tamai, J | 1 |
| Betteridge, DJ; Campbell, RR; Foster, K; McAleer, M; Mundy, D; Reckless, JP; Stirling, C | 1 |
| Davies, GE | 1 |
| Bowman, Z; Cooper, CM; Stanton, HC | 1 |
| Endoh, M; Taira, N; Yanagisawa, T | 1 |
| Boucard, M; Chapat, JP; Cros, GH; McNeill, JH; Milhavet, JC; Rechenq, E; Sablayrolles, C; Serrano, JJ | 1 |
| Ando, H; Kobayashi-Ando, S; Takeya, K; Yajima, M | 1 |
| Abe, H; Fukunami, M; Hori, M; Inoue, M; Ishida, Y; Kitakaze, M; Nakajima, S | 1 |
| Bonnet, PA; Boucard, M; Chapat, JP; Laurent, F; Michel, A | 1 |
| Ando, H; Ando, S; Nomura, H; Takeya, K; Yajima, M | 1 |
| Harding, SE; Poole-Wilson, PA; Wynne, DG | 1 |
| Archer, K; Buchheit, KH; Cook, SJ; Elliott, KR; Foster, RW; Fozard, JR; Martin, A; Miller, AJ; Müller, T; Small, RC | 1 |
| Bompart, J; Bonnet, PA; Boucard, M; Chapat, JP; Hadj-Kaddour, K; Laurent, F; Michel, A | 1 |
| Alberti, KG; Christie, AW; Emmison, N; Kraemer, FB; McCormick, DK; Yeaman, SJ | 1 |
| Advenier, C; Bakdach, H; Bonnet, PA; Cui, YY; Michel, A; Naline, E | 1 |
| A-Rahim, YI; Beyer, KH; Vesell, ES | 1 |
| Eckly-Michel, AE; Le Bec, A; Lugnier, C | 1 |
| Eckly-Michel, A; Lugnier, C; Martin, V | 1 |
| Bonnet, PA; Chiu, P; Elliott, KR; Foster, RW; Isaac, LM; Laurent, F; Michel, A; Pocock, TM; Small, RC | 1 |
| Barnett, CW; Doggrell, SA; Petcu, EB | 1 |
| Fritsche, A; Häring, H; Lehmann, R; Renn, W; Stumvoll, M; Tschritter, O; Wahl, HG | 1 |
| Guo, L; Sun, Y; Wang, A; Xu, C | 1 |
| Kong, L; Luo, A; Ma, J; Qian, C; Ren, Z; Zhang, P; Zhang, S | 1 |
| Ji, XX; Qian, W; Song, XL; Yu, XL; Zhu, JY | 1 |
| Guo, M; Hao, MH; Ma, XY; Sun, WP; Tang, Y; Zhu, HY | 1 |
| Chen, B; Huang, DD; Huang, HH; Li, DG; Yang, Q; Yuan, CL; Zhang, LM | 1 |
| Chen, J; Ji, Y; Li, W; Ma, H; Ma, Y; Shen, J; Shen, Y; Su, SA; Wang, Y; Xiang, M; Xie, Y; Zhang, Y | 1 |
42 other study(ies) available for isoproterenol and pyrazines
| Article | Year |
|---|---|
Effect of amiloride on catecholamine-induced changes in ion transport in short-circuited frog skin.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; Chlorides; Epinephrine; In Vitro Techniques; Isoproterenol; Pyrazines; Rana temporaria; Skin; Sodium | 1978 |
Mitochondrial ATP synthase regulation in heart: defects in hypertension are restored after treatment with captopril.
Topics: Animals; Captopril; Cardiotonic Agents; Cells, Cultured; Electric Stimulation; Hypertension; Isoproterenol; Male; Mitochondria, Heart; Multienzyme Complexes; Myocardium; NADH, NADPH Oxidoreductases; Proton-Translocating ATPases; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ruthenium Red; Verapamil | 1992 |
Studies on the cardiac actions of flosequinan in vitro.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Action Potentials; Animals; Carbachol; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Pyrazines; Pyrrolidinones; Quinolines; Rolipram; Vasodilator Agents | 1992 |
Characterization of the antagonism with metoprolol, ICI 147,798, pindolol, mepindolol and bopindolol on the responses of the rat left atria to isoprenaline.
Topics: Adrenergic beta-Antagonists; Animals; Heart; Isoproterenol; Male; Metoprolol; Myocardial Contraction; Pindolol; Pyrazines; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1992 |
Brain serotoninergic stimulation reduces the water intake induced by systemic and central beta-adrenergic administration.
Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Brain; Drinking; Isoproterenol; Male; Pyrazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Stimulation, Chemical; Time Factors | 1992 |
Implication of cyclic AMP in the positive inotropic effects of cyclic GMP-inhibited cyclic AMP phosphodiesterase inhibitors on guinea pig isolated left atria.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Chloride; Cardiotonic Agents; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Milrinone; Myocardial Contraction; Myocardium; Protoveratrines; Pyrazines; Pyridones; Sodium | 1990 |
Control of mitochondrial ATP synthase in heart cells: inactive to active transitions caused by beating or positive inotropic agents.
Topics: Animals; Calcium; Cardiotonic Agents; Cells, Cultured; Enzyme Activation; Isoproterenol; Male; Mitochondria, Heart; Multienzyme Complexes; Myocardial Contraction; NADH, NADPH Oxidoreductases; Propranolol; Proton-Translocating ATPases; Pyrazines; Rats; Rats, Inbred Strains; Ruthenium Red | 1990 |
Metabolic consequences of positive inotropy in rat and guinea-pig hearts.
Topics: Acidosis; Animals; Chemical Phenomena; Chemistry; Cyclic AMP; Guinea Pigs; Heart; Heart Rate; Isoproterenol; Lactates; Magnetic Resonance Spectroscopy; Male; Myocardium; Perfusion; Phosphates; Pyrazines; Rats | 1990 |
Activation of cyclic AMP-dependent protein kinase during canine lower esophageal sphincter relaxation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiotonic Agents; Dogs; Electric Stimulation; Enzyme Activation; Esophagogastric Junction; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Protein Kinases; Purinones; Pyrazines | 1990 |
Antitachycardiac effect of OPC-8212, a novel cardiotonic agent, on tachycardiac responses of guinea pig isolated right atria to isoproterenol and histamine.
Topics: Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Isoproterenol; Male; Nadolol; Pyrazines; Quinolines; Solvents; Tachycardia; Thiophenes | 1987 |
Analysis of responses to a selective phosphodiesterase III inhibitor, SK&F 94120, on isolated myocardium, including human ventricular myocardium from "end-stage" failure patients.
Topics: Animals; Carbachol; Cats; Female; Guinea Pigs; Heart Failure; Heart Ventricles; Humans; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Pyrazines; Swine | 1987 |
New positive inotropic agent OPC-8212 modulates single Ca2+ channels in ventricular myocytes of guinea pig.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium Channels; Cardiotonic Agents; Colforsin; Cyclic AMP; Depression, Chemical; Dose-Response Relationship, Drug; Guinea Pigs; Heart Ventricles; Isoproterenol; Myocardium; Phosphorylation; Pyrazines; Quinolines | 1989 |
Pharmacological studies with SK&F 94120, a novel positive inotropic agent with vasodilator activity.
Topics: Animals; Cardiotonic Agents; Cats; Female; Guinea Pigs; Hemodynamics; In Vitro Techniques; Isoproterenol; Male; Microspheres; Pyrazines; Rats; Rats, Inbred Strains; Species Specificity; Time Factors; Vascular Resistance; Vasodilator Agents | 1986 |
The evaluation of HBDH and LDH isoenzymes in cardiac cell necrosis of the rat.
Topics: Animals; Female; Heart; Humans; Hydroxybutyrate Dehydrogenase; Isoenzymes; Isoproterenol; L-Lactate Dehydrogenase; Male; Myocardium; Necrosis; Pyrazines; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
Cardiotonic activity of a new inotropic agent, 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), in the dog with and without beta-blocker and Ca++-antagonist pretreatment.
Topics: Animals; Benzazepines; Blood Pressure; Cardiac Output; Cardiotonic Agents; Diltiazem; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Isoproterenol; Pharmaceutical Vehicles; Pyrazines; Quinolines; Thiophenes | 1986 |
Effects of acipimox, a nicotinic acid derivative, on lipolysis in human adipose tissue and on cholesterol synthesis in human jejunal mucosa.
Topics: Adipose Tissue; Cholesterol; Fatty Acids; Glycerol; Humans; Hypolipidemic Agents; In Vitro Techniques; Intestinal Mucosa; Isoproterenol; Jejunum; Lipolysis; Pyrazines | 1985 |
Antibronchoconstrictor activity of two new phosphodiesterase inhibitors, a triazolopyrazine (ICI 58 301) and a triazolopyrimidine (ICI 63 197).
Topics: Acetamides; Acetylcholine; Albuterol; Animals; Bronchi; Bronchial Spasm; Cyclic AMP; Epinephrine; Female; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Isoproterenol; Lung; Male; Perfusion; Phosphodiesterase Inhibitors; Practolol; Propranolol; Pyrazines; Pyrimidines | 1973 |
Effects of monoamine oxidase inhibitors on isoproterenol-induced cardiomegaly in rats.
Topics: Animals; Carbon Isotopes; Cardiomegaly; DNA; Female; Glycine; Isocarboxazid; Isoniazid; Isoproterenol; Monoamine Oxidase Inhibitors; Myocardium; Nialamide; Nucleic Acids; Pargyline; Phenelzine; Piperidines; Pyrazines; Rats; RNA; Tranylcypromine | 1970 |
Involvement of cyclic AMP in the positive inotropic effect of OPC-8212, a new cardiotonic agent, on the canine ventricular muscle.
Topics: Animals; Atenolol; Carbachol; Cardiotonic Agents; Cyclic AMP; Dogs; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Pyrazines; Quinolines; Stimulation, Chemical; Thiophenes | 1984 |
Synthesis of imidazo[1,2-a]pyrazine derivatives with uterine-relaxing, antibronchospastic, and cardiac-stimulating properties.
Topics: Animals; Atrial Function; Bronchial Spasm; Chemical Phenomena; Chemistry; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Heart; Heart Rate; Imidazoles; Isoproterenol; Male; Myocardial Contraction; Propranolol; Pyrazines; Rats; Stimulation, Chemical; Structure-Activity Relationship; Uterine Contraction | 1984 |
Positive inotropic effect of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1 -piperazinyl]-2(1H)-quinolinone (OPC-8212) and mechanism of action in guinea pig ventricular myocardium.
Topics: Animals; Carbachol; Cardiotonic Agents; Cimetidine; Cyclic AMP; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocardial Contraction; Propranolol; Pyrazines; Quinolines; Reserpine | 1984 |
Effects of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl] -2(1H)-quinolinone (OPC-8212), a new inotropic agent, on cardiotonic activity and coronary hemodynamics.
Topics: Animals; Cardiotonic Agents; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Heart Rate; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Oxygen Consumption; Pyrazines; Quinolines | 1984 |
Evaluation of the relaxant effects of SCA40, a novel charybdotoxin-sensitive potassium channel opener, in guinea-pig isolated trachealis.
Topics: Animals; Carbachol; Charybdotoxin; Glyburide; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Potassium Channels; Potassium Chloride; Pyrazines; Scorpion Venoms; Trachea | 1993 |
Relaxing effect of vesnarinone (OPC-8212) on the tracheal muscle strips isolated from guinea pigs.
Topics: 1-Methyl-3-isobutylxanthine; Airway Resistance; Animals; Carbachol; Drug Interactions; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Potassium; Propranolol; Pyrazines; Quinolines; Reserpine; Trachea | 1993 |
Incomplete reversal of beta-adrenoceptor desensitization in human and guinea-pig cardiomyocytes by cyclic nucleotide phosphodiesterase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Guanidines; Guinea Pigs; Heart; Heart Failure; Humans; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Norepinephrine; Pyrazines; Pyridazines | 1993 |
Further analysis of the mechanisms underlying the tracheal relaxant action of SCA40.
Topics: Animals; Cyclic AMP; Electric Stimulation; Electrophysiology; Female; Guinea Pigs; Imidazoles; Isoproterenol; Male; Nifedipine; Parasympatholytics; Pyrazines; Quinine; Theophylline; Trachea | 1995 |
Cardiovascular effects of SCA40, a novel potassium channel opener, in rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Dose-Response Relationship, Drug; Drug Interactions; Heart Atria; Heart Rate; Imidazoles; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Parasympatholytics; Potassium Channels; Propranolol; Pyrazines; Rats; Rats, Wistar | 1993 |
Loss of maximum attenuation and receptor reserve for isoprenaline at the beta 2-adrenoceptors of the portal veins of hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Hypertension; Hypertrophy; Isoproterenol; Male; Nitroprusside; Portal Vein; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Vasodilator Agents; Verapamil | 1995 |
Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes.
Topics: Adenosine Deaminase; Adipocytes; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glycerol; Hypolipidemic Agents; Isoproterenol; Kinetics; Lipase; Lipolysis; Male; Pyrazines; Rats; Rats, Wistar; Subcellular Fractions | 1996 |
Effects of SCA40 on human bronchi and on guinea pig main bronchi in vitro. Comparison with cromakalim.
Topics: Acetylcholine; Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Capsaicin; Charybdotoxin; Cromakalim; Electric Stimulation; Female; Glyburide; Guinea Pigs; Humans; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Nitroprusside; Osmolar Concentration; Parasympatholytics; Potassium Channel Blockers; Potassium Channels; Pyrazines; Pyrroles; Tetraethylammonium; Tetraethylammonium Compounds | 1996 |
Studies on pyrazinoylguanidine. 3. Downregulation of lipolysis in isolated adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Down-Regulation; Glycerol; Guanidines; Hypoglycemic Agents; In Vitro Techniques; Isoproterenol; Lipase; Lipolysis; Male; Pertussis Toxin; Pyrazines; Rats; Rats, Sprague-Dawley; Virulence Factors, Bordetella | 1996 |
Chelerythrine, a protein kinase C inhibitor, interacts with cyclic nucleotide phosphodiesterases.
Topics: Adrenergic beta-Agonists; Alkaloids; Animals; Aorta; Benzophenanthridines; Cardiotonic Agents; Cattle; Drug Interactions; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Glycoproteins; Hydrolysis; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenanthridines; Protein Kinase C; Pyrazines; Rats; Rats, Wistar | 1997 |
Involvement of cyclic nucleotide-dependent protein kinases in cyclic AMP-mediated vasorelaxation.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Aorta; Calcium; Cardiotonic Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pyrazines; Pyrrolidinones; Rats; Rats, Wistar; Rolipram; Signal Transduction; Sulfonamides; Thionucleotides | 1997 |
Effects of SCA40 on bovine trachealis muscle and on cyclic nucleotide phosphodiesterases.
Topics: Animals; Bronchodilator Agents; Cattle; Cromakalim; Dose-Response Relationship, Drug; Electrophysiology; Glycoproteins; Imidazoles; Isoproterenol; Membrane Potentials; Muscle Relaxation; Parasympatholytics; Pyrazines; Rubidium; Trachea | 1997 |
Affinity constants and beta-adrenoceptor reserves for isoprenaline on cardiac tissue from normotensive and hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Female; Heart; Heart Atria; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Isoproterenol; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta | 1998 |
Leptin levels in humans are acutely suppressed by isoproterenol despite acipimox-induced inhibition of lipolysis, but not by free fatty acids.
Topics: Adult; Blood Glucose; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Female; Heparin; Humans; Hypolipidemic Agents; Insulin; Isoproterenol; Leptin; Lipolysis; Male; Pyrazines; Reference Values; Time Factors | 2000 |
Evaluation of antioxidant and immunity function of tetramethylpyrazine phosphate tablets in vivo.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Cardiotonic Agents; Catalase; Glutathione Peroxidase; Heart; Heart Failure; Interleukin-6; Isoproterenol; Malondialdehyde; Organ Size; Organophosphates; Oxidative Stress; Pyrazines; Rats; Rats, Wistar; Superoxide Dismutase; Tablets; Tumor Necrosis Factor-alpha; Ventricular Function, Left | 2012 |
The effect of ligustrazine on L-type calcium current, calcium transient and contractility in rabbit ventricular myocytes.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Female; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Pyrazines; Rabbits; Sympathomimetics; Ventricular Function | 2012 |
Effects and mechanism of action of ligustrazine on isoprenaline-induced cardiomyocyte hypertrophy.
Topics: Animals; Calcium Channel Blockers; Calcium Signaling; Cardiomegaly; Cardiotonic Agents; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Hypertrophy; Isoproterenol; Myocytes, Cardiac; Pyrazines; Rats; Rats, Wistar; Reactive Oxygen Species | 2014 |
Oltipraz attenuates the progression of heart failure in rats through inhibiting oxidative stress and inflammatory response.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Cytokines; Disease Models, Animal; Fibrosis; Heart Failure; Inflammation Mediators; Isoproterenol; Myocytes, Cardiac; Oxidative Stress; Pyrazines; Rats, Sprague-Dawley; Recovery of Function; Thiones; Thiophenes; Ventricular Function, Left; Ventricular Remodeling | 2018 |
Tetramethylpyrazine exerts a protective effect against injury from acute myocardial ischemia by regulating the PI3K/Akt/GSK-3β signaling pathway.
Topics: Animals; Cytokines; Glycogen Synthase Kinase 3 beta; Inflammation; Isoproterenol; Male; Myocardial Ischemia; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Pyrazines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2019 |
Piezo1-Mediated Mechanotransduction Promotes Cardiac Hypertrophy by Impairing Calcium Homeostasis to Activate Calpain/Calcineurin Signaling.
Topics: Adrenergic beta-Agonists; Animals; Calcineurin; Calcium; Calcium Signaling; Calpain; Cardiomegaly; Homeostasis; Ion Channels; Isoproterenol; Mechanotransduction, Cellular; Mice; Mice, Knockout; Myocytes, Cardiac; Pyrazines; Rats; Thiadiazoles | 2021 |