isoproterenol and pirenzepine

isoproterenol has been researched along with pirenzepine in 23 studies

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (17.39)	18.7374
1990's	15 (65.22)	18.2507
2000's	3 (13.04)	29.6817
2010's	1 (4.35)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Fernandes, LB; Fryer, AD; Hirshman, CA	1
Hogenboom, F; Mulder, AH; Schoffelmeer, AN	1
Flavahan, NA; Gunst, SJ; Stropp, JQ	1
Morrow, C; Murphy, S; Pearce, B	1
Carmeliet, P; Denef, C	1
Elzinga, CR; Meurs, H; Roffel, AF; Zaagsma, J	1
Almazan, G; Cohen, RI	1
Ehlert, FJ; Thomas, EA	2
Alloatti, G; Eva, C; Gallo, MP; Levi, RC; Oberto, A	1
Kelly, E; Koenig, SM; Leff, AR; Mitchell, RW; Popovich, KJ; Tallet, J	1
Arana, R; Bacman, S; Borda, E; Camusso, JJ; Hubscher, O; Sterin-Borda, L	1
Akaishi, Y; Hattori, Y; Kanno, M; Kitabatake, A; Sakuma, I	1
Ehlert, FJ; Sawyer, GW	1
Becker, K; Brodde, OE; Jakubetz, J; Konschak, U; Poller, U; Radke, J; Rüter, F; Zerkowski, HR	1
Mitchelson, F; Shen, A	1
Chang, DJ; Cho, NJ; Hwang, JM; Kaang, BK; Lee, YS; Min, CK; Park, YS	1
Ehlert, FJ; Ostrom, RS	1
Haapalinna, A; Larson, J; Niittykoski, M; Ruotsalainen, S; Sirviö, J	1
Herzog, M; Liu, J; Scherer, EQ; Scofield, MA; Shimozono, M; Wangemann, P	1
Ehlert, FJ; Figueroa, KW; Griffin, MT; Liller, S	1

Other Studies

23 other study(ies) available for isoproterenol and pirenzepine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
M2 muscarinic receptors inhibit isoproterenol-induced relaxation of canine airway smooth muscle. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:1 Topics: Animals; Dogs; Drug Interactions; Isoproterenol; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea	1992
M-1 and M-2 muscarinic receptor-mediated inhibition of dopamine-sensitive adenylate cyclase in rat neostriatum: a permissive role for D-2 dopamine receptors. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adenosine; Adenylyl Cyclase Inhibitors; Animals; Atropine; Corpus Striatum; Cyclic AMP; Dopamine; In Vitro Techniques; Isoproterenol; Kinetics; Male; Oxotremorine; Pirenzepine; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Muscarinic; Sulpiride; Vasoactive Intestinal Peptide	1988
Muscarinic receptor reserve and beta-adrenergic sensitivity in tracheal smooth muscle. Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 67, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Dogs; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea	1989
Astrocytes have both M1 and M2 muscarinic receptor subtypes. Brain research, 1986, Jan-29, Volume: 364, Issue:1 Topics: Animals; Astrocytes; Atropine; Benzodiazepinones; Carbachol; Cyclic AMP; Inositol; Isoproterenol; Phospholipids; Pirenzepine; Propranolol; Rats; Receptors, Muscarinic	1986
Immunocytochemical and pharmacological evidence for an intrinsic cholinomimetic system modulating prolactin and growth hormone release in rat pituitary. Endocrinology, 1988, Volume: 123, Issue:2 Topics: Acetylcholine; Animals; Atropine; Benztropine; Carbachol; Cells, Cultured; Choline O-Acetyltransferase; Dexamethasone; Female; Growth Hormone; Hemicholinium 3; Histocytochemistry; Immunoenzyme Techniques; Isoproterenol; Male; Naphthylvinylpyridine; Organ Culture Techniques; Pirenzepine; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Vasoactive Intestinal Peptide	1988
No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea. British journal of pharmacology, 1995, Volume: 115, Issue:4 Topics: Animals; Bronchoconstrictor Agents; Cattle; Dose-Response Relationship, Drug; Gallamine Triethiodide; Histamine; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea	1995
Rat oligodendrocytes express muscarinic receptors coupled to phosphoinositide hydrolysis and adenylyl cyclase. The European journal of neuroscience, 1994, Jul-01, Volume: 6, Issue:7 Topics: Adenylyl Cyclases; Animals; Carbachol; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diamines; Hydrolysis; Isoproterenol; Nerve Tissue Proteins; Oligodendroglia; Phosphatidylinositols; Pirenzepine; Polymerase Chain Reaction; Rats; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate	1994
Pertussis toxin blocks M2 muscarinic receptor-mediated effects on contraction and cyclic AMP in the guinea pig ileum, but not M3-mediated contractions and phosphoinositide hydrolysis. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2 Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Cyclic AMP; Guanosine Triphosphate; Guinea Pigs; Hydrolysis; Ileum; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; N-Methylscopolamine; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Signal Transduction; Virulence Factors, Bordetella	1994
M1 muscarinic receptors increase calcium current and phosphoinositide turnover in guinea-pig ventricular cardiocytes. The Journal of physiology, 1993, Volume: 471 Topics: Animals; Calcium; Carbachol; Cyclic AMP; Female; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; RNA, Messenger; Virulence Factors, Bordetella	1993
Pertussis toxin augments beta-adrenergic relaxation of muscarinic contraction in canine trachealis. The American review of respiratory disease, 1993, Volume: 147, Issue:2 Topics: Acetylcholine; Analysis of Variance; Animals; Dogs; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Pertussis Toxin; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea; Virulence Factors, Bordetella	1993
Involvement of the M2 muscarinic receptor in contractions of the guinea pig trachea, guinea pig esophagus, and rat fundus. Biochemical pharmacology, 1996, Mar-22, Volume: 51, Issue:6 Topics: Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Esophagus; Gastric Fundus; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pertussis Toxin; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Serotonin; Trachea; Virulence Factors, Bordetella	1996
Circulating antibodies against rat parotid gland M3 muscarinic receptors in primary Sjögren's syndrome. Clinical and experimental immunology, 1996, Volume: 104, Issue:3 Topics: Adolescent; Adrenergic beta-Agonists; Adult; Animals; Antibodies, Blocking; Atropine; Carbachol; Carbamates; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin G; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Parotid Gland; Phenylcarbamates; Phosphatidylinositols; Piperidines; Pirenzepine; Protease Inhibitors; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Sjogren's Syndrome	1996
Agonist-independent tonic inhibitory influence of Gi on adenylate cyclase activity in rabbit ventricular myocardium and its removal by pertussis toxin: a role of empty receptor-mediated Gi activation. Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:2 Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atropine; Cell Membrane; Cells, Cultured; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanylyl Imidodiphosphate; Heart Ventricles; Isoproterenol; Male; Muscarinic Antagonists; Pertussis Toxin; Pirenzepine; Propanolamines; Rabbits; Receptor, Muscarinic M2; Receptors, Adrenergic, beta; Receptors, Muscarinic; Virulence Factors, Bordetella	1997
Contractile roles of the M2 and M3 muscarinic receptors in the guinea pig colon. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:1 Topics: Animals; Colforsin; Colon; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Virulence Factors, Bordetella	1998
Cardiac muscarinic receptors decrease with age. In vitro and in vivo studies. The Journal of clinical investigation, 1998, Jan-15, Volume: 101, Issue:2 Topics: Acetylcholine; Adenylyl Cyclases; Adult; Aged; Aging; Child; Dose-Response Relationship, Drug; Heart Transplantation; Humans; Isoproterenol; Male; Middle Aged; Myocardium; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic	1998
Muscarinic M2 receptor-mediated contraction in the guinea pig Taenia caeci: possible involvement of protein kinase C. Biochemical pharmacology, 1998, Dec-01, Volume: 56, Issue:11 Topics: Animals; Cecum; Colforsin; Diphenylacetic Acids; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Piperidines; Pirenzepine; Protein Kinase C; Receptor, Muscarinic M2; Receptors, Muscarinic; Second Messenger Systems	1998
Cloning and expression of a G protein-linked acetylcholine receptor from Caenorhabditis elegans. Journal of neurochemistry, 1999, Volume: 72, Issue:1 Topics: Acetylcholine; Animals; Atropine; Base Sequence; Blotting, Southern; Caenorhabditis elegans; Cloning, Molecular; DNA, Complementary; Electrophysiology; Free Radical Scavengers; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Ion Channel Gating; Isoproterenol; Membrane Potentials; Molecular Sequence Data; Muscarinic Agonists; Muscarinic Antagonists; Oocytes; Oxotremorine; Pirenzepine; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Muscarinic; Scopolamine; Sequence Homology, Amino Acid; Serotonin; Sympathomimetics; Vasodilator Agents; Xenopus	1999
Comparison of functional antagonism between isoproterenol and M2 muscarinic receptors in guinea pig ileum and trachea. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3 Topics: Animals; Colforsin; Diphenylacetic Acids; Guinea Pigs; Histamine; Ileum; Isoproterenol; Muscle Relaxation; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Trachea; Virulence Factors, Bordetella	1999
Activation of muscarinic M3-like receptors and beta-adrenoceptors, but not M2-like muscarinic receptors or alpha-adrenoceptors, directly modulates corticostriatal neurotransmission in vitro. Neuroscience, 1999, Volume: 90, Issue:1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic Fibers; Animals; Carbachol; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Diamines; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Imidazoles; Isoproterenol; Male; Medetomidine; Mice; Mice, Inbred DBA; Muscarinic Agonists; Muscarinic Antagonists; Phenylephrine; Piperidines; Pirenzepine; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Muscarinic; Scopolamine; Synaptic Transmission	1999
Muscarinic receptors control K+ secretion in inner ear strial marginal cells. The Journal of membrane biology, 2001, Aug-01, Volume: 182, Issue:3 Topics: Adrenergic beta-Agonists; Animals; Atropine; Calcium; Carbachol; Cholinergic Agonists; Cloning, Molecular; Cyclic AMP; Diamines; Dose-Response Relationship, Drug; Gerbillinae; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Potassium; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Stria Vascularis	2001
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Algorithms; Animals; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidines; Receptor, Muscarinic M2; Signal Transduction; Transfection	2007