isoproterenol has been researched along with piperidines in 137 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (45.26) | 18.7374 |
| 1990's | 31 (22.63) | 18.2507 |
| 2000's | 23 (16.79) | 29.6817 |
| 2010's | 19 (13.87) | 24.3611 |
| 2020's | 2 (1.46) | 2.80 |
| Authors | Studies |
|---|---|
| Aghajanian, GK; Cedarbaum, JM | 1 |
| Marlin, GE; Turner, P | 2 |
| Svedmyr, N; Thiringer, G; Ydreborg, SO | 1 |
| Avery, GS; Brogden, RN; Pinder, RM; Speight, TM | 1 |
| Eriksson, NE; Lindgren, SB | 1 |
| Adams, L; Ead, H; Hayward, RP; Spurrell, RA; Stephens, JD | 1 |
| Karasawa, A; Kasuya, Y; Takayanagi, I | 1 |
| Cho, YW; Ito, H; Matsukawa, H; Okabe, E; Sakamoto, H | 1 |
| Jeffrey, PL | 1 |
| Adams, GK; Bleidt, B; Diamond, L; Williams, B | 1 |
| Chignell, CF; Sinha, BK | 1 |
| Daniell, HB; Saelens, DA; Webb, JG | 1 |
| Jackson, G; Jackson, PG; Jewitt, DE; Kitson, D | 1 |
| Jackson, PG; Jennings, K; Jewitt, D | 1 |
| Bassett, AL; Gibson, JK; Somani, P | 1 |
| Avner, SE | 1 |
| Bianco, S; Kamburoff, PL; Prime, FJ | 1 |
| De Wilde, A; Janssen, PA; Reneman, RS; van Bogaert, A; van Bogaert, PP; Wellens, D; Wouters, L | 1 |
| Nichimura, T; Sakamoto, M; Sasao, T; Yanaura, S | 1 |
| Iwabuchi, Y; Masuhara, T | 1 |
| Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Fernandes, LB; Fryer, AD; Hirshman, CA | 1 |
| Jaiswal, N; Malik, KU | 1 |
| Jurkiewicz, NK; Sanguinetti, MC; Scott, A; Siegl, PK | 1 |
| Kang, YS; Ohnishi, T; Terasaki, T; Tsuji, A | 1 |
| Hjemdahl, P; Kahan, T | 1 |
| Flavahan, NA; Gunst, SJ; Stropp, JQ | 1 |
| Chaudhary, BA; Kolbeck, RC; Speir, WA | 1 |
| Goto, K; Ishikawa, T; Miyauchi, T; Saito, A; Sugishita, Y | 1 |
| Gulliver, PA; Raxworthy, MJ; Youde, IR | 1 |
| Banerjee, AK; De Boer, HJ; Dhasmana, KM; Saxena, PR | 1 |
| Heiligers, J; Mylecharane, EJ; Saxena, PR | 1 |
| Engel, G; Göthert, M; Hillenbrand, K; Hoyer, D; Schlicker, E | 1 |
| Arneklo-Nobin, B; Owman, C | 1 |
| Culver, PJ; Rattan, S | 1 |
| Admant, P; Brembilla-Perrot, B; Le Helloco, A; Pernot, C | 1 |
| Bellani, D; Gibelli, A; Montanari, C; Sacchetti, G | 1 |
| Malm, L | 1 |
| Edvinsson, L; Owman, C | 1 |
| Bowman, Z; Cooper, CM; Stanton, HC | 1 |
| Alps, BJ; Borrows, ET; Johnson, ES; Staniforth, MW; Wilson, AB | 1 |
| Willems, JL | 1 |
| Dollery, CT; George, CF; Lewis, PJ | 1 |
| Inatomi, N; Takagi, K; Takayanagi, I; Uruno, T | 1 |
| Kubota, K; Takagi, K; Takayanagi, I; Uruno, T | 1 |
| Kaverina, NV; Mirzoian, RS; Rozonov, IuB | 1 |
| Alps, BJ; Hill, M; Johnson, ES; Wilson, AB | 1 |
| Chen, SC; Kasuya, Y; Munakata, H; Watanabe, H | 1 |
| Marinova, VM; Phillips, EM; Turner, P; Woolnough, M | 1 |
| Günthner, W; Kamburoff, PL; Prime, FJ | 1 |
| Malmberg, R; Svedmyr, N; Thiringer, G | 1 |
| Gailer, KA; Hornsey, PA; Turner, P | 1 |
| Hashimoto, H; Kasuya, Y | 1 |
| Fontaine, J; Janssen, PA; Van Nueten, JM | 1 |
| Ferko, AP | 2 |
| Hudak, WJ; Kuhn, WL; Lewis, RE | 1 |
| Bowman, WC; Rodger, IW | 1 |
| Grewal, RS; Kaul, CL | 1 |
| Cohen, BM | 1 |
| Cho, YW; Fujisawa, T; Higashi, H; Ito, H; Okabe, E | 1 |
| Higuchi, K; Sakai, K; Uchida, M; Yamaguchi, T | 1 |
| Diamond, L; O'Donnell, M | 1 |
| Basu, AK; Gupta, MP; Kaur, AH; Seth, SD | 1 |
| Mulder, GH; Smelik, PG; Tilders, FJ; Vemes, I | 1 |
| Giuliani, S; Maggi, CA; Zagorodnyuk, V | 1 |
| Elzinga, CR; Meurs, H; Roffel, AF; Zaagsma, J | 1 |
| Eglen, RM; Reddy, H; Watson, N | 1 |
| Ajiki, K; Inoue, H; Iwasawa, K; Murakawa, Y; Nakajima, T; Oikawa, N; Omata, M; Sezaki, K; Usui, M; Yamashita, T | 1 |
| Eglen, RM; Watson, N | 1 |
| Holzer, P; Maggi, CA | 1 |
| Clark, CD; Hume, JR; Levesque, PC; Rosenshtraukh, LV; Zakarov, SI | 1 |
| Shikada, K; Tanaka, S | 1 |
| Martin, CL; Mcmahon, EG; Palomo, MA | 1 |
| Arana, R; Bacman, S; Borda, E; Camusso, JJ; Hubscher, O; Sterin-Borda, L | 1 |
| Itoh, Y; Kimura, K; Oka, M; Shimidzu, T; Ukai, Y; Yoshikuni, Y | 1 |
| Deng, XF; Mulay, S; Varma, DR | 1 |
| Ehlert, FJ; Sawyer, GW | 1 |
| Bril, A; Faivre, JF; Rouanet, S | 1 |
| Ehlert, FJ; Ostrom, RS | 2 |
| Mitchelson, F; Shen, A | 1 |
| Chiba, S; Furukawa, Y; Hoyano, Y; Kasama, M; Oguchi, T | 1 |
| Cordier, J; Giaume, C; Glowinski, J; Sagan, S; Torrens, Y; Venance, L | 1 |
| Haapalinna, A; Larson, J; Niittykoski, M; Ruotsalainen, S; Sirviö, J | 1 |
| Fukuchi, Y; Kira, S; Muramatsu, M; Ohnishi, M; Oka, M; Sato, K | 1 |
| Iijima, T; Ishikawa, K; Kurata, S | 1 |
| Goto, A; Hazama, H; Iwasawa, K; Morita, T; Nakajima, T; Oonuma, H; Wang, Y | 1 |
| Cheng, J; Kamiya, K; Kodama, I; Liu, W; Toyama, J; Tsuji, Y | 1 |
| Ichikawa, T; Kawanishi, T; Masumiya, H; Matsui, S; Okazaki, K; Shigenobu, K; Tanaka, H | 1 |
| Calcerrada, MC; Catalán, RE; Hernández, F; Martínez, AM; Pérez-Alvarez, MJ | 1 |
| Catalán, RE; Hernández, F; Martínez, AM; Piedra, D | 1 |
| Endoh, M; Watanabe, T | 1 |
| Potter, DE; Thompson, WJ; Zhou, L | 1 |
| Araki, M; Fujita, M; Hasegawa, K; Iwai-Kanai, E; Kakita, T; Morimoto, T; Sasayama, S; Sawamura, T; Wada, H | 1 |
| Herzog, M; Liu, J; Scherer, EQ; Scofield, MA; Shimozono, M; Wangemann, P | 1 |
| Chapple, CR; Chess-Williams, R; Yamanishi, T; Yasuda, K | 1 |
| Advenier, C; Cortijo, J; Molimard, M; Morcillo, EJ; Moreau, J; Naline, E; Sarria, B; Therond, P; Zhang, Y | 1 |
| MANNAIONI, PF | 1 |
| JACOBSON, ED; KALAS, JP | 1 |
| Crimin, K; Fossa, AA; Gorczyca, W; Magnano, A; Raunig, DL; Winslow, R; Wisialowski, T; Wolfgang, E | 1 |
| Kinsella, BT; O'Meara, SJ | 1 |
| Abe, DM; Ehlert, FJ; Griffin, MT; Manabe, T; Matsui, M; Taketo, MM; Vo, TH | 1 |
| Bartha, E; Czopf, L; Deres, P; Halmosi, R; Hantó, K; Hideg, K; Kálai, T; Kulcsár, G; Pálfi, A; Sümegi, B; Szabados, E; Tóth, A; Tóth, K | 1 |
| Moravec, CS; Ogletree, ML; Sprung, J | 1 |
| Bianchetti, A; Croci, T; Di Marzo, V; Di Palo, S; Ferla, G; Guagnini, F; Matias, I; Mukenge, S; Valenti, M | 1 |
| Clements, JM; Vanhoose, AM; Winder, DG | 1 |
| Ronkainen, J; Ruskoaho, H; Vierimaa, H; Vuolteenaho, O | 1 |
| Bányász, T; Birinyi, P; Horváth, B; Magyar, J; Nánási, PP; Szentandrássy, N | 1 |
| Deres, P; Gallyas, F; Halmosi, R; Hanto, K; Hideg, K; Kalai, T; Kulcsar, G; Palfi, A; Sumegi, B; Szabados, E; Szereday, Z; Toth, A; Toth, K | 1 |
| Birkeland, JA; Bjørnerheim, R; Brattelid, T; Krobert, KA; Levy, FO; Moberg, ER; Osnes, JB; Qvigstad, E; Sejersted, OM; Sjaastad, I; Skomedal, T | 1 |
| Ehlert, FJ; Figueroa, KW; Griffin, MT; Liller, S | 1 |
| Barbieri, SF; Brar, BK; Gattuso, A; Mahata, SK; Mannarino, C; Mazza, R; Tota, B | 1 |
| Guo, DH; Hu, Y; Liu, P; Rahman, K; Wang, B; Wang, DX | 1 |
| Hata, K; Ito, M; Kawashima, S; Kijima, Y; Kita, T; Nakajima, H; Nishikawa, Y; Okamoto, M; Seo, T; Takaya, T; Yodoi, K | 1 |
| Chen, IJ; Dai, ZK; Hsu, JH; Liou, SF; Liu, CP; Wu, BN; Wu, JR; Wu, PJ; Yeh, JL | 1 |
| Gong, ZH; Liu, Y; Lu, XQ; Yan, H | 1 |
| Henry, PJ; Mann, TS; Taylor, SJ | 1 |
| Aizer, A; Bloom, M; Chinitz, L; Linton, P; O'Neill, DK; Rose, E | 1 |
| Bányász, T; Bárándi, L; Farkas, V; Hegyi, B; Horváth, B; Magyar, J; Márton, I; Nánási, PP; Ruzsnavszky, F; Szentandrássy, N | 1 |
| Ashihara, T; Honjo, H; Inada, S; Kamiya, K; Kato, S; Kodama, I; Nakazawa, K; Okuno, Y; Opthof, T; Sakuma, I; Suzuki, T; Takanari, H; Takemoto, Y | 1 |
| Abdelhamid, G; Althurwi, HN; El-Kadi, AO; Hammock, BD; Tse, MM; Zordoky, BN | 1 |
| Chen, A; Fowlkes, C; Grosberg, A; Khine, M; Lee, E; Santiago, K; Tu, R | 1 |
| Ando, T; Furukawa, T; Hayakawa, T; Kanda, Y; Kobayashi, S; Kunihiro, T; Kurokawa, J; Matsui, E; Yada, H | 1 |
| Dahlenborg, K; Kunze, A; Sartipy, P; Steel, D; Svedhem, S | 1 |
| Abu-Nada, L; Al-Subaie, A; Alebrahim, S; Eimar, H; Manickam, G; Murshed, M; Tamimi, F | 1 |
| Akhtar, M; Hass, C; Khanam, R; Najmi, AK; Panda, BP | 1 |
| Beyer, A; Ganti, B; Majkrzak, A; Theyyunni, N | 1 |
| Chirayil, HT; Dhivya, V; Huang, CY; Padma, VV; Priya, LB; Sathiskumar, S | 1 |
| Ma, J; Song, Z; Wang, J; Wang, S; Wang, X; Zhao, Q | 1 |
| Ma, ZG; Tang, QZ; Wang, SS; Xu, SC; Yuan, YP; Zhang, X | 1 |
| Bakkers, J; de Boer, TP; Knöpfel, T; Kok, BJM; Koopman, CD; Orger, MB; Renninger, SL; van Opbergen, CJM; van Veen, TAB; Vos, MA | 1 |
| Kossakowski, R; Malinowska, B; Pędzińska-Betiuk, A; Weresa, J | 1 |
| Hu, X; Li, T; Liu, J; Ou-Yang, Q; Wang, L; Xie, X | 1 |
| Aliev, G; Beeraka, NM; Chubarev, VN; Dhivya, V; Gavryushova, LV; Huang, CY; Mikhaleva, LM; Minyaeva, NN; Tarasov, VV; Viswanadha, VP | 1 |
| Akashi, M; Harada, A; Ito, E; Matsusaki, M; Miyagawa, S; Mochizuki-Oda, N; Sawa, Y; Takeda, M | 1 |
2 review(s) available for isoproterenol and piperidines
| Article | Year |
|---|---|
Rimiterol: a review of its pharmacological properties and therapeutic efficacy in asthma.
Topics: Absorption; Administration, Oral; Aerosols; Albuterol; Animals; Asthma; Bronchodilator Agents; Catechols; Clinical Trials as Topic; Half-Life; Hemodynamics; Humans; In Vitro Techniques; Injections, Intravenous; Isoproterenol; Kinetics; Muscle Contraction; Myocardial Contraction; Organ Specificity; Piperidines; Terbutaline; Tremor | 1977 |
Beta-adrenergic bronchodilators.
Topics: Administration, Oral; Aerosols; Albuterol; Animals; Anisoles; Asthma; Bronchi; Bronchial Spasm; Bronchodilator Agents; Catechols; Drug Evaluation, Preclinical; Ethanolamines; Hexoprenaline; Humans; Injections; Isoproterenol; Isoquinolines; Methanol; Piperidines; Resorcinols; Respiratory Therapy | 1975 |
10 trial(s) available for isoproterenol and piperidines
| Article | Year |
|---|---|
Comparison of the beta2-adrenoceptor selectivity of rimiterol, salbutamol and isoprenaline by the intravenous route in man.
Topics: Adult; Albuterol; Catechols; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Isoproterenol; Male; Middle Aged; Piperidines; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1975 |
Comparison of rimiterol and terbutaline, given by aerosol, in a long-term study.
Topics: Aerosols; Asthma; Bronchitis; Catechols; Chronic Disease; Drug Evaluation; Female; Humans; Isoproterenol; Lung Diseases, Obstructive; Male; Piperidines; Pulmonary Emphysema; Terbutaline | 1977 |
Rimiterol: a review of its pharmacological properties and therapeutic efficacy in asthma.
Topics: Absorption; Administration, Oral; Aerosols; Albuterol; Animals; Asthma; Bronchodilator Agents; Catechols; Clinical Trials as Topic; Half-Life; Hemodynamics; Humans; In Vitro Techniques; Injections, Intravenous; Isoproterenol; Kinetics; Muscle Contraction; Myocardial Contraction; Organ Specificity; Piperidines; Terbutaline; Tremor | 1977 |
The rapidity of bronchodilatation. A comparison of isoprenaline, terbutaline and rimiterol.
Topics: Adult; Aged; Asthma; Bronchodilator Agents; Bronchospirometry; Catechols; Clinical Trials as Topic; Drug Evaluation; Female; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; Piperidines; Terbutaline; Time Factors | 1978 |
The relative potencies and beta2-selectivities of intravenous rimiterol, salbutamol and isoprenaline in asthmatic patients.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Blood Pressure; Bronchi; Bronchodilator Agents; Catechols; Clinical Trials as Topic; Dose-Response Relationship, Drug; Forced Expiratory Volume; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; Piperidines; Placebos; Tremor; Vital Capacity | 1975 |
Comparison between the bronchodilator and cardiovascular effects of inhaling 0.5 mg. rimiterol ('Pulmadil') and 0.2 mg. salbutamol.
Topics: Adult; Aerosols; Airway Obstruction; Albuterol; Asthma; Blood Pressure; Bronchi; Bronchitis; Bronchodilator Agents; Cardiovascular System; Catechols; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Isoproterenol; Male; Methanol; Middle Aged; Piperidines; Respiratory Function Tests; Respiratory Therapy | 1975 |
Clinical evaluation of indoramin, a new antihypertensive agent.
Topics: Angiotensin II; Antihypertensive Agents; Benzamides; Blood Pressure; Body Weight; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Tolerance; Female; Heart Rate; Humans; Hypertension; Indoles; Isoproterenol; Male; Norepinephrine; Piperidines; Placebos; Regression Analysis; Time Factors | 1973 |
A comparison of isoprenaline, salbutamol, and rimiterol inhalation on skin temperature, heart rate, and respiration in man.
Topics: Adrenergic beta-Agonists; Adult; Aerosols; Amino Alcohols; Bronchial Spasm; Butylamines; Catechols; Clinical Trials as Topic; Electrocardiography; Female; Heart Rate; Histamine; Humans; Isoproterenol; Male; Methanol; Phenethylamines; Piperidines; Respiration; Skin Temperature; Sympathomimetics; Vasodilator Agents | 1972 |
The effect of a new adrenergic beta 2 -receptor-stimulating agent (rimiterol, R798) in patients with chronic obstructive lung disease.
Topics: Adrenergic beta-Agonists; Adult; Aerosols; Amino Alcohols; Bronchi; Bronchodilator Agents; Catechols; Dose-Response Relationship, Drug; Heart Rate; Humans; In Vitro Techniques; Infant, Newborn; Isoproterenol; Lung Diseases; Methanol; Middle Aged; Muscle Contraction; Muscle, Smooth; Piperidines; Placebos; Respiration; Spirometry; Stimulation, Chemical; Time Factors | 1972 |
Isoproterenol infusion increases level of consciousness during catheter ablation of atrial fibrillation.
Topics: Adult; Aged; Anesthetics, Intravenous; Atrial Fibrillation; Catheter Ablation; Consciousness; Electroencephalography; Female; Humans; Infusions, Intravenous; Isoproterenol; Male; Middle Aged; Monitoring, Intraoperative; Piperidines; Remifentanil; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome | 2012 |
126 other study(ies) available for isoproterenol and piperidines
| Article | Year |
|---|---|
Noradrenergic neurons of the locus coeruleus: inhibition by epinephrine and activation by the alpha-antagonist piperoxane.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Ventricles; Clonidine; Epinephrine; gamma-Aminobutyric Acid; Iontophoresis; Isoproterenol; Male; Norepinephrine; Piperidines; Rats; Sotalol | 1976 |
Comparative peripheral and coronary haemodynamic effects of rimiterol and isoprenaline.
Topics: Adult; Catechols; Coronary Circulation; Hemodynamics; Humans; Isoproterenol; Male; Middle Aged; Myocardium; Oxygen Consumption; Piperidines; Regional Blood Flow | 1978 |
Relaxation of depolarized guinea pig taenia caecum induced by some antispasmodics.
Topics: Animals; Benactyzine; Bucladesine; Calcium; Cecum; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Papaverine; Parasympatholytics; Piperidines | 1978 |
Cardiovascular effects of isoproterenol and possible antagonistic actions of propranolol and perhexiline.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiac Output; Dogs; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Perhexiline; Piperidines; Propranolol; Rabbits | 1978 |
Biochemical actions of sympathomimetic drugs which overcome cycloheximide-induced amnesia.
Topics: Adenosine Triphosphatases; Amnesia; Amphetamines; Animals; Brain; Chickens; Cycloheximide; Enzyme Activation; Humans; Isoproterenol; Male; Methoxamine; Norepinephrine; Ouabain; Piperidines; Piperoxan; Potassium; Propranolol; Protein Biosynthesis; Sodium; Synaptosomes | 1976 |
Experimental study of a potential anti-asthmatic agent: SCH 15280.
Topics: Adrenergic beta-Antagonists; Aerosols; Airway Resistance; Aminophylline; Animals; Atropine; Benzopyrans; Bronchodilator Agents; Cats; Female; Histamine H1 Antagonists; Injections, Intravenous; Isoproterenol; Male; Methacholine Compounds; Piperidines; Pyridines; Rabbits | 1975 |
Synthesis and biological activity of spin-labeled analogs of biotin, hexamethonium, decamethonium, dichlorisoproterenol, and propranolol.
Topics: Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Avidin; Binding Sites; Biotin; Cholinesterase Inhibitors; Decamethonium Compounds; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Piperidines; Propranolol; Rats; Spin Labels | 1975 |
The effects of perhexiline on the sympathetic nervous system.
Topics: Animals; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Dogs; Electric Stimulation; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Myocardium; Norepinephrine; Perhexiline; Piperidines; Rats; Sympathetic Nervous System; Vagotomy; Vas Deferens | 1979 |
The inotropic effects of UK 14,275, a phosphodiesterase inhibitor, in man.
Topics: Adult; Drug Interactions; Humans; Isoproterenol; Male; Myocardial Contraction; Phosphodiesterase Inhibitors; Piperidines; Propranolol; Quinazolines; Stimulation, Chemical | 1978 |
Efficacy of new inotropic drugs in clinical coronary heart failure.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Catecholamines; Dobutamine; Heart Failure; Heart Rate; Hemodynamics; Humans; Infusions, Parenteral; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Phonocardiography; Phosphodiesterase Inhibitors; Piperidines; Pressure; Quinazolines; Vascular Resistance | 1978 |
Electrophysiologic effects of encainide (MJ 9067) on canine Purkinje fibres.
Topics: Action Potentials; Anilides; Animals; Anti-Arrhythmia Agents; Dogs; Heart Conduction System; In Vitro Techniques; Isoproterenol; Membrane Potentials; Ouabain; Piperidines; Purkinje Fibers | 1978 |
Unusual mechanism of hypotensive activity exerted by erytrho-1-(1-[2-(1,4-benzodioxan-2-yl)-2-OH-ET-a1-4-piperidyl)-2-benzimidazolinone (R 28935).
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Carotid Arteries; Clonidine; Dioxanes; Dogs; Electric Stimulation; Female; Hindlimb; Hypothalamus; Isoproterenol; Male; Norepinephrine; Piperidines; Pressoreceptors; Regional Blood Flow | 1975 |
The role of bronchoconstriction in cough reflex.
Topics: Airway Resistance; Animals; Antitussive Agents; Bronchi; Bronchial Spasm; Bronchodilator Agents; Codeine; Cough; Dogs; Ethanolamines; Female; Isoproterenol; Male; Morphine; Phenylacetates; Picolines; Piperidines; Propranolol | 1975 |
Effects of cholinergic and adrenergic agonists on the secretion of fluid and protein by submandibular glands of the hamster and the rat.
Topics: Animals; Cricetinae; Isoproterenol; Male; Mesocricetus; Metoprolol; Parasympathomimetics; Phenylephrine; Pilocarpine; Piperidines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cholinergic; Saliva; Salivary Proteins and Peptides; Submandibular Gland; Sympathomimetics | 1992 |
Effects of anti-asthma drugs and potassium channel openers on neurally-mediated contraction of isolated guinea pig trachea.
Topics: Acetylcholine; Aminophylline; Animals; Benzopyrans; Cromakalim; Electric Stimulation; Guinea Pigs; Hydrocortisone; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Oxadiazoles; Piperidines; Potassium Channels; Pyrroles; Trachea | 1992 |
M2 muscarinic receptors inhibit isoproterenol-induced relaxation of canine airway smooth muscle.
Topics: Animals; Dogs; Drug Interactions; Isoproterenol; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1992 |
Methoctramine, a cardioselective antagonist: muscarinic receptor mediating prostaglandin synthesis in isolated rabbit heart.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Arecoline; Coronary Circulation; Diamines; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardium; Parasympatholytics; Piperidines; Prostaglandins; Rabbits; Receptors, Muscarinic | 1991 |
Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes. Mechanism of action.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cell Separation; Electric Conductivity; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Myocardium; Papillary Muscles; Piperidines; Pyridines; Refractory Period, Electrophysiological | 1991 |
In vivo and in vitro evidence for a common carrier mediated transport of choline and basic drugs through the blood-brain barrier.
Topics: Animals; Biological Transport; Biphenyl Compounds; Blood-Brain Barrier; Capillaries; Choline; Drug Carriers; Isoproterenol; Kinetics; Male; Parasympatholytics; Piperidines; Propiophenones; Rats; Scopolamine; Thiamine; Tritium | 1990 |
Prejunctional beta 2-adrenoceptor-mediated enhancement of noradrenaline release in skeletal muscle vasculature in situ.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dogs; Female; Isoproterenol; Male; Muscles; Neuromuscular Junction; Norepinephrine; Piperidines; Propanolamines; Receptors, Adrenergic, beta; Synaptic Transmission | 1987 |
Muscarinic receptor reserve and beta-adrenergic sensitivity in tracheal smooth muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Dogs; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea | 1989 |
Effect of glucocorticoids on the response of airway smooth muscle to catecholamine and resorcinol beta-agonists.
Topics: Adrenergic beta-Antagonists; Animals; Catecholamines; Fenoterol; Glucocorticoids; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Isoproterenol; Male; Methylprednisolone; Muscle Contraction; Muscle, Smooth; Piperidines; Resorcinols; Terbutaline; Trachea | 1989 |
Involvement of calcitonin gene-related peptide in the positive chronotropic and inotropic effects of piperine and development of cross-tachyphylaxis between piperine and capsaicin in the isolated rat atria.
Topics: Alkaloids; Animals; Benzodioxoles; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Neuropeptides; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tachyphylaxis | 1989 |
Catechol-O-methyltransferase: substrate-specificity and stereoselectivity for beta-adrenoceptor agents.
Topics: Adrenergic beta-Antagonists; Animals; Catechol O-Methyltransferase; Dobutamine; Isoetharine; Isoproterenol; Kinetics; Methylation; Nadolol; Norepinephrine; Piperidines; Propanolamines; Receptors, Adrenergic, beta; Stereoisomerism; Substrate Specificity; Swine | 1986 |
Analysis of the tachycardiac response to 5-hydroxytryptamine in the spinal guinea-pig.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Decerebrate State; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Piperidines; Propranolol; Reserpine; Serotonin; Serotonin Antagonists; Tyramine | 1988 |
Analysis of the heart rate effects of 5-hydroxytryptamine in the cat; mediation of tachycardia by 5-HT1-like receptors.
Topics: Animals; Blood Pressure; Cats; Female; Heart Rate; Isoproterenol; Ketanserin; Male; Methysergide; Piperidines; Propranolol; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tropanes; Vagus Nerve | 1985 |
Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites.
Topics: Animals; Cerebral Cortex; In Vitro Techniques; Isoproterenol; Ketanserin; Kinetics; Male; Pindolol; Piperidines; Rats; Receptors, Serotonin; Serotonin Antagonists; Subcellular Fractions; Swine | 1986 |
Adrenergic and serotoninergic mechanisms in human hand arteries and veins studied by fluorescence histochemistry and in vitro pharmacology.
Topics: Arteries; Binding, Competitive; Biogenic Amines; Epinephrine; Female; Hand; Humans; Isoproterenol; Ketanserin; Male; Microscopy, Fluorescence; Muscle Contraction; Norepinephrine; Phentolamine; Piperidines; Receptors, Adrenergic; Serotonin; Sympathetic Nervous System; Veins | 1985 |
Influence of loperamide on the internal anal sphincter in the opossum.
Topics: Anal Canal; Animals; Drug Interactions; Electric Stimulation; Female; Isoproterenol; Loperamide; Male; Naloxone; Nicotine; Opossums; Piperidines; Pressure; Rectum; Spinal Nerve Roots; Verapamil | 1987 |
Loss of efficacy of flecainide in the Wolff-Parkinson-White syndrome after isoproterenol administration.
Topics: Adult; Anti-Arrhythmia Agents; Electrocardiography; Female; Flecainide; Heart Block; Heart Conduction System; Heart Rate; Humans; Isoproterenol; Piperidines; Wolff-Parkinson-White Syndrome | 1985 |
Effects "in vitro" of some cardiovascular drugs and other agents on human platelet aggregation.
Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Aniline Compounds; Humans; In Vitro Techniques; Indoles; Isoproterenol; Male; Norepinephrine; Papaverine; Phentolamine; Piperidines; Platelet Adhesiveness | 1973 |
Vasodilatation in the nasal mucosa of the cat and the effects of parasympatholytic and beta-adrenergic blocking agents.
Topics: Acetamides; Adrenergic beta-Antagonists; Animals; Atropine; Blood Flow Velocity; Cats; Electric Stimulation; Isoproterenol; Maxillary Nerve; Methacholine Compounds; Nasal Mucosa; Parasympatholytics; Piperidines; Propranolol; Stimulation, Chemical; Venous Pressure | 1973 |
Pharmacological characterization of adrenergic alpha and beta receptors mediating the vasomotor responses of cerebral arteries in vitro.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cats; Cerebral Arteries; Dibenzylchlorethamine; Dioxins; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Male; Mathematics; Norepinephrine; Phenoxybenzamine; Piperidines; Propranolol; Receptors, Adrenergic; Terbutaline; Vasomotor System | 1974 |
Effects of monoamine oxidase inhibitors on isoproterenol-induced cardiomegaly in rats.
Topics: Animals; Carbon Isotopes; Cardiomegaly; DNA; Female; Glycine; Isocarboxazid; Isoniazid; Isoproterenol; Monoamine Oxidase Inhibitors; Myocardium; Nialamide; Nucleic Acids; Pargyline; Phenelzine; Piperidines; Pyrazines; Rats; RNA; Tranylcypromine | 1970 |
A comparison of the cardiovascular actions of indoramin, propranolol, lignocaine, and quinidine.
Topics: Amides; Angiotensin II; Animals; Blood Pressure; Cats; Depression, Chemical; Epinephrine; Female; Heart; Heart Rate; Hemodynamics; Indoles; Isoproterenol; Lidocaine; Male; Muscle Contraction; Norepinephrine; Piperidines; Propranolol; Quinidine; Vascular Resistance | 1972 |
Dopamine-induced inhibition of synaptic transmission in lumbar paravertebral ganglia of the dog.
Topics: Acetamides; Action Potentials; Animals; Antihypertensive Agents; Apomorphine; Blood Pressure; Butyrophenones; Catecholamines; Chlorpromazine; Dogs; Dopamine; Dose-Response Relationship, Drug; Ergonovine; Ganglia, Spinal; Haloperidol; Isoproterenol; Methane; Norepinephrine; Phenoxybenzamine; Phentolamine; Pimozide; Piperidines; Synapses; Synaptic Transmission; Vasodilator Agents | 1973 |
Anti-oxytocin actions of papaverine, aspaminol and isoprenaline on the rat uterus and intracellular cyclin adenosine 3,5-monophosphate level.
Topics: Animals; Benzyl Compounds; Butanols; Cyclic AMP; Female; In Vitro Techniques; Isoproterenol; Oxytocin; Papaverine; Piperidines; Rats; Uterus | 1973 |
Comparison of actions of papaverine, aspaminol and isoprenaline on isolated rat uterus.
Topics: Aminophylline; Animals; Benzyl Compounds; Butanols; Cyclic AMP; Drug Synergism; Female; Imidazoles; In Vitro Techniques; Isoproterenol; Muscle Contraction; Oxytocin; Papaverine; Phosphodiesterase Inhibitors; Piperidines; Rats; Uterus | 1974 |
[The importance of central monoaminergic mechanisms in the effect of pharmacologic substances on the reflex reactions of the heart].
Topics: Analgesics; Animals; Catecholamines; Cats; Coronary Vessels; Iproniazid; Isoproterenol; Monoamine Oxidase Inhibitors; Morphine; Piperidines; Reflex; Reserpine; Serotonin; Tranylcypromine; Vascular Resistance; Vasomotor System | 1967 |
Autonomic blocking properties of Wy 21901.
Topics: Adrenergic alpha-Antagonists; Amides; Anesthesia, Local; Animals; Aorta; Guinea Pigs; Heart; Heart Rate; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Indoles; Isoproterenol; Male; Muscle, Smooth; Norepinephrine; Piperidines; Rabbits; Sympatholytics; Vas Deferens | 1970 |
Effect of L-dopa, adrenergic -blockers and anticholinergic agents on the tremorine-tremor in mice.
Topics: Adrenergic beta-Antagonists; Amino Alcohols; Animals; Dihydroxyphenylalanine; Drug Combinations; Hydrazines; Isoproterenol; Male; Mice; Parasympatholytics; Phenethylamines; Piperidines; Propranolol; Stereoisomerism; Sympatholytics; Tranylcypromine; Tremor; Tremorine | 1971 |
Comparison of the bronchodilatory action of two drugs.
Topics: Adrenergic beta-Agonists; Adult; Aerosols; Airway Obstruction; Airway Resistance; Blood Pressure; Bronchodilator Agents; Catechols; Humans; Isoproterenol; Male; Methanol; Piperidines; Plethysmography, Whole Body; Pulse; Respiratory Function Tests; Spirometry; Time Factors; Vital Capacity | 1971 |
The relative potency of some -adrenoreceptor agonists on isolated human vein.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino Alcohols; Butylamines; Catechols; Drug Combinations; Humans; In Vitro Techniques; Isoproterenol; Methanol; Phenethylamines; Piperidines; Propranolol; Propylamines; Saphenous Vein; Sympathomimetics | 1971 |
Potentiation of cardiovascular effects of catecholamines by a diphenylalkanolamine.
Topics: Animals; Blood Pressure; Butanols; Catecholamines; Cats; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Female; Heart Rate; Hemodynamics; Isoproterenol; Male; Nictitating Membrane; Norepinephrine; Piperidines; Respiration; Time Factors; Tritium | 1974 |
Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 3: in vitro studies on the peristaltic reflex and other experiments on isolated tissues.
Topics: Amides; Animals; Antidiarrheals; Cats; Cecum; Chickens; Chlorobenzenes; Duodenum; Electric Stimulation; Gastrointestinal Agents; Gastrointestinal Motility; Guinea Pigs; Heart Rate; Histamine; Ileum; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Nicotine; Papillary Muscles; Peristalsis; Piperidines; Rabbits; Rats; Spleen; Stomach | 1974 |
A comparison of some cardiovascular and skeletal muscle effects of 1-allyl-2-benzyl-piperidine and lidocaine.
Topics: Allyl Compounds; Animals; Anti-Arrhythmia Agents; Anura; Atropine; Benzyl Compounds; Blood Pressure; Cats; Electrocardiography; Heart Rate; Hemodynamics; Isoproterenol; Lidocaine; Male; Muscles; Norepinephrine; Piperidines; Propranolol; Tubocurarine; Vasodilator Agents | 1973 |
Cardiovascular pharmacology of perhexiline.
Topics: Amidohydrolases; Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Cardiovascular System; Coronary Vessels; Guinea Pigs; Heart Conduction System; Heart Rate; Heart, Artificial; Injections, Intra-Arterial; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nitroglycerin; Perfusion; Piperidines; Reserpine; Time Factors; Vascular Resistance | 1970 |
Some cardiac effects of 1-allyl-2-benzyl-piperidine hc1, in vitro and in vivo.
Topics: Alkenes; Allyl Compounds; Animals; Anti-Arrhythmia Agents; Anura; Benzyl Compounds; Calcium Chloride; Depression, Chemical; Drug Antagonism; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Lethal Dose 50; Lidocaine; Neuromuscular Junction; Norepinephrine; Ouabain; Piperidines; Sciatic Nerve; Ventricular Fibrillation | 1972 |
Actions of the sympathomimetic bronchodilator, rimiterol (R798), on the cardiovascular, respiratory and skeletal muscle systems of the anaesthetized cat.
Topics: Amino Alcohols; Animals; Blood Pressure; Bronchodilator Agents; Catechols; Cats; Female; Heart; Heart Rate; Injections, Intravenous; Isoproterenol; Lung; Male; Methanol; Muscle Contraction; Muscles; Piperidines; Serotonin Antagonists; Stimulation, Chemical | 1972 |
Adrenaline reversal by CIBA 1002-Go.
Topics: Acetylcholine; Animals; Blood Pressure; Cats; Cocaine; Depression, Chemical; Dogs; Drug Synergism; Epinephrine; Female; Heart Rate; Hexamethonium Compounds; Imipramine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Piperidines; Propranolol; Pyrazoles; Rabbits; Rats; Receptors, Drug; Stimulation, Chemical; Uterus | 1969 |
A progress note on pimetine hydrochloride in obstructive ventilatory disease.
Topics: Adult; Aminophylline; Cough; Dyspnea; Female; Humans; Isoproterenol; Male; Middle Aged; Piperidines; Pulmonary Emphysema; Respiratory Function Tests; Respiratory Insufficiency; Respiratory System; Sputum | 1967 |
Effects of perhexiline on myocardial phosphorylase activity, myocardial catecholamine content and heart rate.
Topics: Animals; Catecholamines; Heart Rate; Isoproterenol; Male; Myocardium; Norepinephrine; Perhexiline; Phosphorylase Kinase; Piperidines; Propranolol; Rats | 1981 |
Oxytocin-induced Ca-free contraction of rat uterine smooth muscle: effects of preincubation with EGTA and drugs.
Topics: Animals; Calcium; Drug Interactions; Egtazic Acid; Ethylene Glycols; Female; Isoproterenol; Oxytocin; Piperidines; Rats; Rats, Inbred Strains; Time Factors; Uterine Contraction | 1982 |
A comparative study of two parasympatholytic bronchodilator agents: ipratropium bromide and diphemanil methylsulfate.
Topics: Animals; Atropine; Atropine Derivatives; Bronchodilator Agents; Female; Guinea Pigs; In Vitro Techniques; Ipratropium; Isoproterenol; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Potassium Chloride; Trachea | 1981 |
Effect of perhexilene on 86Rb uptake in experimental myocardial infarction.
Topics: Animals; Biological Transport, Active; Disease Models, Animal; Female; Heart; Isoproterenol; Male; Myocardial Infarction; Myocardium; Perhexiline; Piperidines; Rats; Rats, Inbred Strains; Rubidium | 1981 |
Differential control of beta-endorphin/beta-lipotropin secretion from anterior and intermediate lobes of the rat pituitary gland in vitro.
Topics: Animals; Benzimidazoles; beta-Lipotropin; Catecholamines; Domperidone; Dopamine; Endorphins; Female; Isoproterenol; Organ Specificity; Perfusion; Piperidines; Pituitary Gland; Pituitary Gland, Anterior; Propranolol; Rats | 1980 |
Tachykinin NK3 receptor mediates NANC hyperpolarization and relaxation via nitric oxide release in the circular muscle of the guinea-pig colon.
Topics: Animals; Apamin; Arginine; Atropine; Colon; Dose-Response Relationship, Drug; Guanethidine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Neurokinin B; Nitric Oxide; Nitroarginine; Oligopeptides; Peptide Fragments; Piperidines; Quinuclidines; Receptors, Neurokinin-3; Stereoisomerism; Substance P; Tetrodotoxin | 1994 |
No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea.
Topics: Animals; Bronchoconstrictor Agents; Cattle; Dose-Response Relationship, Drug; Gallamine Triethiodide; Histamine; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea | 1995 |
Role of muscarinic M2 and M3 receptors in guinea-pig trachea: effects of receptor alkylation.
Topics: Alkylation; Animals; Diamines; Dioxolanes; Diphenylacetic Acids; Drug Interactions; Guinea Pigs; Histamine; Isoproterenol; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Receptors, Muscarinic; Stimulation, Chemical; Trachea | 1995 |
Effect of isoproterenol on facilitation of electrical defibrillation by E-4031.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Dogs; Drug Interactions; Electric Countershock; Electric Stimulation; Electrophysiology; Heart Rate; Injections, Intravenous; Isoproterenol; Piperidines; Pyridines | 1995 |
Effects of muscarinic M2 and M3 receptor stimulation and antagonism on responses to isoprenaline of guinea-pig trachea in vitro.
Topics: Animals; Diamines; Dioxolanes; Guinea Pigs; Histamine; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Receptors, Muscarinic; Trachea | 1994 |
Synergistic role of muscarinic acetylcholine and tachykinin NK-2 receptors in intestinal peristalsis.
Topics: Animals; Atropine; Benzamides; Calcitonin Gene-Related Peptide; Drug Synergism; Female; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Intestines; Isoproterenol; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peristalsis; Piperidines; Receptors, Cholinergic; Receptors, Neurokinin-2 | 1994 |
Anion and cation modulation of the guinea-pig ventricular action potential during beta-adrenoceptor stimulation.
Topics: Action Potentials; Animals; Anions; Anthracenes; Anti-Arrhythmia Agents; Calcium Channels; Cations; Chloride Channels; Cyclic AMP; Guinea Pigs; Heart; Isoproterenol; Membrane Proteins; Piperidines; Potassium Channels; Pyridines; Receptors, Adrenergic, beta; Ventricular Function | 1993 |
Influence of epithelium on the inhibition of melittin-induced contraction of guinea-pig isolated trachea by the potassium channel opener NIP-121.
Topics: Aminophylline; Animals; Arachidonate Lipoxygenases; Epithelium; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Isoproterenol; Leukotriene D4; Male; Melitten; Muscle Contraction; Muscle, Smooth; Oxadiazoles; Piperidines; Potassium Channels; Trachea | 1993 |
Comparison of bidisomide, flecainide and dofetilide on action potential duration in isolated canine atria: effect of isoproterenol.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; Dose-Response Relationship, Drug; Flecainide; Guinea Pigs; Heart Atria; Isoproterenol; Male; Phenethylamines; Piperidines; Sulfonamides | 1996 |
Circulating antibodies against rat parotid gland M3 muscarinic receptors in primary Sjögren's syndrome.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Animals; Antibodies, Blocking; Atropine; Carbachol; Carbamates; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin G; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Parotid Gland; Phenylcarbamates; Phosphatidylinositols; Piperidines; Pirenzepine; Protease Inhibitors; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Sjogren's Syndrome | 1996 |
Involvement of metabotropic glutamate receptors in Gi- and Gs-dependent modulation of adenylate cyclase activity induced by a novel cognition enhancer NS-105 in rat brain.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Alanine; Animals; Baclofen; Brimonidine Tartrate; Cell Membrane; Cerebral Cortex; Cholera Toxin; Cognition; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoproterenol; Kinetics; Male; Manganese; Pertussis Toxin; Piperidines; Proline; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Neurotransmitter; Virulence Factors, Bordetella; Yohimbine | 1997 |
Role of Ca(2+)-independent PKC in alpha 1-adrenoceptor-mediated inotropic responses of neonatal rat hearts.
Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Calcium; Carbazoles; Diacylglycerol Kinase; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Heart Ventricles; In Vitro Techniques; Indoles; Inositol Phosphates; Isoenzymes; Isoproterenol; Maleimides; Methoxamine; Myocardial Contraction; Myocardium; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Protein Kinase C; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 1997 |
Contractile roles of the M2 and M3 muscarinic receptors in the guinea pig colon.
Topics: Animals; Colforsin; Colon; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Virulence Factors, Bordetella | 1998 |
Comparative effects of glibenclamide, tedisamil, dofetilide, E-4031, and BRL-32872 on protein kinase A-activated chloride current in guinea pig ventricular myocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetylcholine; Animals; Anti-Arrhythmia Agents; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Cardiotonic Agents; Chlorides; Cyclic AMP-Dependent Protein Kinases; Cyclopropanes; Glyburide; Guinea Pigs; Heart Ventricles; Hypoglycemic Agents; Ion Transport; Isoproterenol; Male; Myocardium; Patch-Clamp Techniques; Phenethylamines; Piperidines; Potassium Channels; Propranolol; Pyridines; Sulfonamides | 1998 |
M2 muscarinic receptors inhibit forskolin- but not isoproterenol-mediated relaxation in bovine tracheal smooth muscle.
Topics: Animals; Cattle; Colforsin; Cyclic AMP; Diphenylacetic Acids; Histamine; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Oxotremorine; Piperidines; Receptor, Muscarinic M2; Receptors, Muscarinic; Trachea | 1998 |
Muscarinic M2 receptor-mediated contraction in the guinea pig Taenia caeci: possible involvement of protein kinase C.
Topics: Animals; Cecum; Colforsin; Diphenylacetic Acids; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Piperidines; Pirenzepine; Protein Kinase C; Receptor, Muscarinic M2; Receptors, Muscarinic; Second Messenger Systems | 1998 |
Effects of low temperature on the chronotropic and inotropic responses to zatebradine, E-4031 and verapamil in isolated perfused dog atria.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Calcium Channel Agonists; Cardiovascular Agents; Cold Temperature; Dogs; Dose-Response Relationship, Drug; Heart Atria; Hypothermia, Induced; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Perfusion; Piperidines; Pyridines; Verapamil | 1998 |
Comparison of functional antagonism between isoproterenol and M2 muscarinic receptors in guinea pig ileum and trachea.
Topics: Animals; Colforsin; Diphenylacetic Acids; Guinea Pigs; Histamine; Ileum; Isoproterenol; Muscle Relaxation; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Trachea; Virulence Factors, Bordetella | 1999 |
Anandamide and WIN 55212-2 inhibit cyclic AMP formation through G-protein-coupled receptors distinct from CB1 cannabinoid receptors in cultured astrocytes.
Topics: Adrenergic beta-Agonists; Animals; Arachidonic Acids; Astrocytes; Benzoxazines; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Endocannabinoids; GTP-Binding Proteins; Isoproterenol; Mice; Morpholines; Naphthalenes; Neurons; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tritium; Virulence Factors, Bordetella | 1999 |
Activation of muscarinic M3-like receptors and beta-adrenoceptors, but not M2-like muscarinic receptors or alpha-adrenoceptors, directly modulates corticostriatal neurotransmission in vitro.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic Fibers; Animals; Carbachol; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Diamines; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Imidazoles; Isoproterenol; Male; Medetomidine; Mice; Mice, Inbred DBA; Muscarinic Agonists; Muscarinic Antagonists; Phenylephrine; Piperidines; Pirenzepine; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Muscarinic; Scopolamine; Synaptic Transmission | 1999 |
E4021, a selective phosphodiesterase 5 inhibitor, potentiates the vasodilator effect of inhaled nitric oxide in isolated perfused rat lungs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Inhalation; Animals; Bronchodilator Agents; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Hypertension, Pulmonary; In Vitro Techniques; Isoproterenol; Lung; Male; Nitric Oxide; Nitroprusside; Perfusion; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperidines; Pulmonary Circulation; Quinazolines; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation | 1999 |
Enhancement by arginine vasopressin of the L-type Ca2+ current in guinea pig ventricular myocytes.
Topics: Animals; Arginine Vasopressin; Calcium; Calcium Channels; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Isoproterenol; Piperidines; Potassium Channels; Quinolones | 1999 |
Antiarrhythmic effect and its underlying ionic mechanism of 17beta-estradiol in cardiac myocytes.
Topics: Action Potentials; Androgens; Animals; Anti-Arrhythmia Agents; Calcium Channels; Calcium Channels, L-Type; Cardiotonic Agents; Estradiol; Estrogen Antagonists; Estrogens, Non-Steroidal; Female; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Pyridines | 1999 |
Heterogeneous distribution of the two components of delayed rectifier K+ current: a potential mechanism of the proarrhythmic effects of methanesulfonanilideclass III agents.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Electric Stimulation; Female; Heart Ventricles; Isoproterenol; Male; Patch-Clamp Techniques; Piperidines; Potassium Channels; Pyridines; Rabbits; Time Factors | 1999 |
Calcium channel antagonistic effects of AH-1058, a novel antiarrhythmic drug, on guinea-pig myocardium.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Bridged Bicyclo Compounds; Calcium Channel Blockers; Drug Synergism; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Piperidines | 1999 |
Endothelin-1 increases isoprenaline-enhanced cyclic AMP levels in cerebral cortex.
Topics: Adenosine Deaminase; Adrenergic beta-Agonists; Animals; Calcium; Cerebral Cortex; Cyclic AMP; Endothelin Receptor Antagonists; Endothelin-1; Isoproterenol; Male; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Wistar | 2000 |
Endothelin inhibits histamine-induced cyclic AMP accumulation in bovine brain vessels.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood-Brain Barrier; Brain; Capillaries; Cattle; Cyclic AMP; Endothelin Receptor Antagonists; Endothelin-1; Histamine; Histamine Antagonists; Isoproterenol; Microcirculation; Oligopeptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Second Messenger Systems; Viper Venoms | 2000 |
Antiadrenergic effects of endothelin-1 on the L-type Ca2+ current in dog ventricular myocytes.
Topics: Adrenergic Antagonists; Animals; Calcium Channels, L-Type; Dogs; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Female; Heart; Isoproterenol; Male; Oligopeptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B | 2000 |
Functional identification of phosphodiesterase activity in human trabecular meshwork cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Cells, Cultured; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Humans; Isoproterenol; Nitroprusside; Piperidines; Quinazolines; Signal Transduction; Trabecular Meshwork | 2000 |
Endothelin-1 as a protective factor against beta-adrenergic agonist-induced apoptosis in cardiac myocytes.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Anti-Bacterial Agents; Apoptosis; Azepines; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Flavonoids; Heart; Indoles; Isoproterenol; Myocardium; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sirolimus | 2000 |
Muscarinic receptors control K+ secretion in inner ear strial marginal cells.
Topics: Adrenergic beta-Agonists; Animals; Atropine; Calcium; Carbachol; Cholinergic Agonists; Cloning, Molecular; Cyclic AMP; Diamines; Dose-Response Relationship, Drug; Gerbillinae; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Potassium; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Stria Vascularis | 2001 |
The role of M2 muscarinic receptor subtypes in mediating contraction of the pig bladder base after cyclic adenosine monophosphate elevation and/or selective M3 inactivation.
Topics: Animals; Cyclic AMP; Diamines; Female; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Piperidines; Potassium Chloride; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Swine; Urinary Bladder | 2002 |
Muscarinic M2 receptors in acetylcholine-isoproterenol functional antagonism in human isolated bronchus.
Topics: Acetylcholine; Bronchi; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Lung Neoplasms; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Piperidines; Receptor, Muscarinic M2; Receptors, Muscarinic | 2002 |
Interaction between histamine and dichloroisoproterenol, hexamethonium, pempidine, and diphenhydramine, in normal and reserpine-treated heart preparations.
Topics: Diphenhydramine; Ganglionic Blockers; Guinea Pigs; Heart; Hexamethonium; Hexamethonium Compounds; Histamine; Isoproterenol; Myocardium; Nicotine; Pempidine; Piperidines; Reserpine; Sympatholytics | 1960 |
THE EFFECT OF VASOACTIVE ANTAGONISTS IN ENDOTOXIN SHOCK.
Topics: Animals; Atropine; Blood Circulation; Blood Pressure; Blood Pressure Determination; Chloralose; Cyproheptadine; Diphenhydramine; Dogs; Endotoxins; Hemorrhage; Histamine H1 Antagonists; Histamine Release; Humans; Hypertension; Hypertension, Portal; Isoproterenol; Morphine; p-Methoxy-N-methylphenethylamine; Pharmacology; Phenothiazines; Phenoxybenzamine; Piperidines; Research; Reserpine; Shigella; Shock, Septic; Splenic Artery; Sympatholytics; Vasodilator Agents | 1964 |
Dynamic beat-to-beat modeling of the QT-RR interval relationship: analysis of QT prolongation during alterations of autonomic state versus human ether a-go-go-related gene inhibition.
Topics: Adrenergic beta-Agonists; Animals; Bradycardia; Dogs; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Heart Rate; Humans; Isoproterenol; Long QT Syndrome; Nitroprusside; Phenylephrine; Piperidines; Potassium Channels, Voltage-Gated; Pyridines; Tachycardia | 2005 |
The effect of the farnesyl protein transferase inhibitor SCH66336 on isoprenylation and signalling by the prostacyclin receptor.
Topics: Adrenergic beta-Agonists; Alkyl and Aryl Transferases; Amino Acid Motifs; Animals; Calcium Signaling; Carrier Proteins; Cell Line; Cell Line, Tumor; Cyclic AMP; Dose-Response Relationship, Drug; Endocytosis; Epoprostenol; Farnesyltranstransferase; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; Humans; Iloprost; Isoproterenol; Kidney; Leukemia, Erythroblastic, Acute; Mice; Mutagenesis, Site-Directed; Organophosphorus Compounds; Piperidines; Proline; Propanolamines; Protein Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Pyridines; Receptors, Adrenergic, beta-2; Receptors, Epoprostenol; Receptors, Thromboxane A2, Prostaglandin H2; Recombinant Fusion Proteins; Signal Transduction; Transfection | 2005 |
The M2 muscarinic receptor mediates contraction through indirect mechanisms in mouse urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Binding, Competitive; Colforsin; Dinoprost; Diphenylacetic Acids; In Vitro Techniques; Isoproterenol; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Oxotremorine; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2005 |
The role of Akt and mitogen-activated protein kinase systems in the protective effect of poly(ADP-ribose) polymerase inhibition in Langendorff perfused and in isoproterenol-damaged rat hearts.
Topics: Animals; Energy Metabolism; Enzyme Inhibitors; Heart; Hydrogen Peroxide; Isoproterenol; Lipid Peroxidation; Male; Mitogen-Activated Protein Kinases; Myocardium; Perfusion; Phosphorylation; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Protective Agents; Proteins; Quinazolines; Rats; Rats, Sprague-Dawley | 2005 |
Effects of remifentanil on the contractility of failing human heart muscle.
Topics: Adrenergic beta-Agonists; Adult; Aged; Anesthetics, Intravenous; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart; Heart Failure; Humans; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Piperidines; Remifentanil | 2005 |
Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Modulators; Case-Control Studies; Colon; Diverticulum; Endocannabinoids; Female; Glycerides; Humans; Imidazoles; Isoproterenol; Male; Middle Aged; Morpholines; Muscle Contraction; Muscle, Smooth; Naphthalenes; Neurokinin-1 Receptor Antagonists; Piperidines; Polyunsaturated Alkamides; Propanolamines; Pyrazoles; Quinuclidines; Rimonabant; Substance P; Tetrodotoxin | 2006 |
Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcineurin Inhibitors; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Marine Toxins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxazoles; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperidines; Protein Phosphatase 1; Protein Phosphatase 2; Protein Processing, Post-Translational; Receptors, Adrenergic, beta-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2006 |
Synergistic activation of salmon cardiac function by endothelin and beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Animals; Dose-Response Relationship, Drug; Drug Synergism; Endothelin Receptor Antagonists; Endothelin-1; Female; Fish Proteins; Gene Expression Regulation; Heart; Isoproterenol; Male; Myocardial Contraction; Natriuretic Peptides; Oligopeptides; Piperidines; RNA, Messenger; Salmo salar | 2006 |
Contribution of I Ks to ventricular repolarization in canine myocytes.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Cell Polarity; Chromans; Computer Simulation; Delayed Rectifier Potassium Channels; Dogs; Female; Heart Rate; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Piperidines; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Pyridines; Sulfonamides; Sympathetic Nervous System; Ventricular Function | 2006 |
PARP inhibition prevents postinfarction myocardial remodeling and heart failure via the protein kinase C/glycogen synthase kinase-3beta pathway.
Topics: Animals; Cardiomegaly; Collagen Type III; Electrocardiography; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart Failure; Isoproterenol; Male; Mitogen-Activated Protein Kinases; Myocardial Infarction; Natriuretic Peptide, Brain; Phosphorylation; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Kinase C; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Ventricular Remodeling | 2006 |
Effects of treatment with a 5-HT4 receptor antagonist in heart failure.
Topics: Adrenergic beta-Agonists; Animals; Cardiac Output; Heart Failure; Indoles; Isoproterenol; Lung; Male; Myocardial Contraction; Myocardium; Organ Size; Piperidines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Serotonin, 5-HT4; RNA, Messenger; Serotonin 5-HT4 Receptor Antagonists; Up-Regulation; Ventricular Function, Left; Ventricular Remodeling | 2007 |
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Algorithms; Animals; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidines; Receptor, Muscarinic M2; Signal Transduction; Transfection | 2007 |
Catestatin (chromogranin A344-364) is a novel cardiosuppressive agent: inhibition of isoproterenol and endothelin signaling in the frog heart.
Topics: Animals; Calcium-Binding Proteins; Cardiotonic Agents; Cattle; Chromogranin A; Depression, Chemical; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Oxadiazoles; Peptide Fragments; Phosphorylation; Piperidines; Quinoxalines; Rana esculenta; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Stroke Volume | 2008 |
Antioxidant effects of a Rhodobryum roseum extract and its active components in isoproterenol-induced myocardial injury in rats and cardiac myocytes against oxidative stress-triggered damage.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Antioxidants; Aspartate Aminotransferases; Bryophyta; Cardiomyopathies; Cell Survival; Creatine Kinase; Dioxolanes; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Isoproterenol; L-Lactate Dehydrogenase; Myocytes, Cardiac; Oxidants; Oxidative Stress; Piperidines; Rats | 2009 |
Torsades de Pointes with QT prolongation related to donepezil use.
Topics: Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Colitis; Donepezil; Electrocardiography; Female; Humans; Indans; Isoproterenol; Lidocaine; Long QT Syndrome; Magnesium Sulfate; Nootropic Agents; Piperidines; Potassium Chloride; Syncope; Torsades de Pointes; Treatment Outcome | 2009 |
KMUP-1 attenuates isoprenaline-induced cardiac hypertrophy in rats through NO/cGMP/PKG and ERK1/2/calcineurin A pathways.
Topics: Animals; Calcineurin; Cardiomegaly; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Drug Delivery Systems; Fibrosis; Isoproterenol; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase; Piperidines; Rats; Rats, Wistar; Signal Transduction; Survival Rate; Xanthines | 2010 |
[Establishment of isolated rabbit airway smooth muscles responsiveness model for the pharmacodynamic study of anti-rhinoviruses drugs].
Topics: Acetylcholine; Animals; Antiviral Agents; Cytopathogenic Effect, Viral; HeLa Cells; Humans; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Piperidines; Pyridazines; Rabbits; Rhinovirus; Trachea | 2010 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Inflammation; Influenza A virus; Isoproterenol; Leukocytes; Male; Mice; Mice, Inbred BALB C; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Orthomyxoviridae Infections; Piperidines; Prostaglandin Antagonists; Respiratory Mucosa; Specific Pathogen-Free Organisms; Substance P; Trachea; TRPV Cation Channels; Xanthones | 2012 |
Role of action potential configuration and the contribution of C²⁺a and K⁺ currents to isoprenaline-induced changes in canine ventricular cells.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Calcium Channels, L-Type; Chromans; Delayed Rectifier Potassium Channels; Dogs; Female; Isoproterenol; Male; Myocytes, Cardiac; Nisoldipine; Patch-Clamp Techniques; Piperidines; Pyridines; Sulfonamides | 2012 |
Pharmacological blockade of IKs destabilizes spiral-wave reentry under β-adrenergic stimulation in favor of its early termination.
Topics: Action Potentials; Adrenergic Agents; Animals; Arrhythmias, Cardiac; Chromans; Heart Ventricles; Isoproterenol; Myocardium; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Rabbits; Sulfonamides; Sympathetic Nervous System | 2012 |
Soluble epoxide hydrolase inhibitor, TUPS, protects against isoprenaline-induced cardiac hypertrophy.
Topics: Animals; Atrial Natriuretic Factor; Body Weight; Cardiomegaly; Cardiotonic Agents; Cell Line; Cytochrome P-450 Enzyme System; Drug Antagonism; Epoxide Hydrolases; Gene Expression Regulation; Heart; Humans; Isoproterenol; Kidney; Liver; Natriuretic Peptide, Brain; Phenylurea Compounds; Piperidines; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction | 2013 |
Integrated platform for functional monitoring of biomimetic heart sheets derived from human pluripotent stem cells.
Topics: Anti-Arrhythmia Agents; Biomimetics; Cell Differentiation; Cells, Cultured; Humans; Inhibitory Concentration 50; Isoproterenol; Myocytes, Cardiac; Piperidines; Pluripotent Stem Cells; Pyridines | 2014 |
Image-based evaluation of contraction-relaxation kinetics of human-induced pluripotent stem cell-derived cardiomyocytes: Correlation and complementarity with extracellular electrophysiology.
Topics: Adrenergic beta-Agonists; Biomechanical Phenomena; Calcium Channel Blockers; Calcium Signaling; Cell Differentiation; Cells, Cultured; Electrophysiologic Techniques, Cardiac; Humans; Induced Pluripotent Stem Cells; Isoproterenol; Kinetics; Microscopy, Video; Myocardial Contraction; Myocytes, Cardiac; Piperidines; Pyridines; Sodium Channel Blockers; Tetrodotoxin; Verapamil | 2014 |
Non-Invasive Acoustical sensing of Drug-Induced Effects on the Contractile Machinery of Human Cardiomyocyte Clusters.
Topics: Biosensing Techniques; Cell Line; Cytochalasin D; Humans; Isoproterenol; Myocytes, Cardiac; Nifedipine; Piperidines; Pyridines; Quartz Crystal Microbalance Techniques | 2015 |
Donepezil regulates energy metabolism and favors bone mass accrual.
Topics: Animals; Biomechanical Phenomena; Bone and Bones; Cell Count; Donepezil; Energy Metabolism; Female; Indans; Isoproterenol; Mice, Inbred C57BL; Organ Size; Osteoclasts; Piperidines | 2016 |
Histamine H3 Receptor Agonist Imetit Attenuated Isoproterenol Induced Renin Angiotensin System and Sympathetic Nervous System Overactivity in Myocardial Infarction of Rats.
Topics: Angiotensin II; Animals; Antioxidants; Cardiotonic Agents; Histamine Agonists; Histamine H3 Antagonists; Imidazoles; Isoproterenol; Losartan; Male; Myocardial Infarction; Myocardium; Norepinephrine; Piperidines; Rats; Renin-Angiotensin System; Sympathetic Nervous System; Thiourea | 2016 |
A Perfect Storm: Tyrosine Kinase Inhibitor-Associated Polymorphic Ventricular Tachycardia.
Topics: Adenine; Amiodarone; Anti-Arrhythmia Agents; Antineoplastic Agents; Cardiotonic Agents; Electric Countershock; Electrocardiography; Electrophysiology; Emergency Service, Hospital; Extracorporeal Membrane Oxygenation; Humans; Intensive Care Units; Intra-Aortic Balloon Pumping; Isoproterenol; Lidocaine; Magnesium; Male; Middle Aged; Piperidines; Pyrazoles; Pyrimidines; Respiration, Artificial; Syncope; Tachycardia, Ventricular; Torsades de Pointes; Waldenstrom Macroglobulinemia; Workforce | 2017 |
Piperine modulates isoproterenol induced myocardial ischemia through antioxidant and anti-dyslipidemic effect in male Wistar rats.
Topics: Alkaloids; Animals; Antioxidants; Benzodioxoles; Biomarkers; Heart; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Oxidative Stress; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Wistar | 2017 |
Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes.
Topics: Cardiotoxicity; Cell Differentiation; Drug Discovery; Haloperidol; Human Embryonic Stem Cells; Humans; Induced Pluripotent Stem Cells; Isoproterenol; Myocytes, Cardiac; Piperidines; Pyridines; Quinidine | 2017 |
Piperine Attenuates Pathological Cardiac Fibrosis Via PPAR-γ/AKT Pathways.
Topics: Alkaloids; Angiotensin II; Anilides; Animals; Benzodioxoles; Cell Differentiation; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Fibroblasts; Fibrosis; Glycogen Synthase Kinase 3 beta; Heart; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Myocardium; Myofibroblasts; Piperidines; Polyunsaturated Alkamides; PPAR gamma; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta | 2017 |
Optogenetic sensors in the zebrafish heart: a novel in vivo electrophysiological tool to study cardiac arrhythmogenesis.
Topics: Animals; Anti-Arrhythmia Agents; Biological Clocks; Electrophysiologic Techniques, Cardiac; Electrophysiological Phenomena; Heart; Heart Rate; Humans; Isoproterenol; Microscopy, Fluorescence; Optogenetics; Piperidines; Propranolol; Pyridines; Zebrafish | 2018 |
Cannabinoid CB
Topics: Adrenergic beta-Agonists; Animals; Cannabinoid Receptor Antagonists; Drug Interactions; Heart Atria; Heart Rate; In Vitro Techniques; Indoles; Isoproterenol; Male; Myocardial Contraction; Piperidines; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Adrenergic, beta-1; Signal Transduction | 2019 |
AdipoRon prevents l-thyroxine or isoproterenol-induced cardiac hypertrophy through regulating the AMPK-related pathway.
Topics: AMP-Activated Protein Kinases; Animals; Atrial Natriuretic Factor; Body Weight; Cardiomegaly; Gene Expression; Isoproterenol; Male; Natriuretic Peptide, Brain; Organ Size; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Piperidines; Rats, Sprague-Dawley; Signal Transduction; Thyroxine | 2019 |
The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity.
Topics: Adrenergic beta-Agonists; Alkaloids; Animals; Benzodioxoles; Cardiomegaly; Cytokines; Endothelium; Fibrosis; Inflammation; Isoproterenol; Male; Myocardial Infarction; Myocardium; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Wistar; Signal Transduction; Transcription Factor RelA | 2020 |
Development of a drug screening system using three-dimensional cardiac tissues containing multiple cell types.
Topics: Animals; Drug Evaluation, Preclinical; Extracellular Matrix; Gene Expression Regulation; Heart; Heart Rate; Imaging, Three-Dimensional; Induced Pluripotent Stem Cells; Ion Channels; Isoproterenol; Mice; Myocardial Contraction; Piperidines; Pyridines | 2021 |