isoproterenol and pinacidil

isoproterenol has been researched along with pinacidil in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.00)18.7374
1990's16 (64.00)18.2507
2000's2 (8.00)29.6817
2010's5 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Berry, JL; Foster, RW; Small, RC1
Bishop, BE; Doggrell, SA1
Charette, L; Garcia, ML; Jones, TR; Kaczorowski, GJ1
Hood, JS; Kadowitz, PJ; McMahon, TJ1
Cohen, GA; Hyman, AL; Lippton, HL; McMurtry, IF1
Angus, JA; McPherson, GA1
MacLeod, KM; Ray, A1
Cohen, ML; Schoepp, DD; Secrest, RJ1
Banerjee, SP; Davidson, WR; Kawashima, S; Liang, CS1
Chang, JK; Heaton, J; Hyman, A; Lin, B; Lippton, H; Steinberg, S1
Dave, KC; Goyal, RK; Mehta, AA1
Banitt, PF; Dai, HB; Friedman, M; Sellke, FW; Wang, SY1
Barnett, CW; Bishop, BE; Doggrell, SA1
Akatsuka, Y; Egashira, K; Imamura, Y; Kasuya, H; Narishige, T; Takahashi, T; Takeshita, A1
Jackson, WF1
Franklin, A; Hariawala, MD; Li, J; Sellke, FW; Stamler, A; Tofukuji, M1
D'Alonzo, AJ; Darbenzio, RB; Dorso, CR; Grover, GJ; Zhu, JL1
Tabrizchi, R1
Dick, JM; Lefebvre, RA; Timmermans, JP; Van Geldre, LA1
Matsuda, N; Sellke, FW1
Morita, H; Morita, ST; Wu, J; Zipes, DP1
Daida, H; Matsumoto, A; Miyata, Y; Nakaya, H; Nakazato, Y; Nishimura, N; Ogura, T; Reien, Y; Suzuki, K1

Other Studies

25 other study(ies) available for isoproterenol and pinacidil

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Tracheal relaxation induced by potassium channel opening drugs: its antagonism by adrenergic neurone blocking agents.
    British journal of pharmacology, 1992, Volume: 106, Issue:4

    Topics: Adrenergic Antagonists; Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Female; Guanidines; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Parasympatholytics; Picolines; Pinacidil; Potassium Channels; Pyrans; Pyrroles; Rubidium Radioisotopes; Stereoisomerism; Theophylline; Trachea

1992
Effects of potassium channel openers and calcium channel blockers on the force responses of the electrically driven rat right ventricle strip.
    Journal of autonomic pharmacology, 1992, Volume: 12, Issue:1

    Topics: Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Electric Stimulation; Guanidines; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Inbred Strains; Ventricular Function, Right

1992
Selective inhibition of relaxation of guinea-pig trachea by charybdotoxin, a potent Ca(++)-activated K+ channel inhibitor.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Aminophylline; Animals; Benzopyrans; Calcium; Carbachol; Charybdotoxin; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Guanidines; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Nitroprusside; Pinacidil; Potassium Channels; Pyrroles; Scorpion Venoms; Serotonin; Trachea

1990
Pulmonary vasodilator responses to RP 52891 are mediated by activation of a glibenclamide-sensitive K+ATP channel.
    European journal of pharmacology, 1991, Sep-04, Volume: 202, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine Triphosphate; Animals; Benzopyrans; Blood Gas Analysis; Blood Pressure; Cats; Cromakalim; Female; Glyburide; Guanidines; Hydrogen-Ion Concentration; Isoproterenol; Male; Nitroprusside; Picolines; Pinacidil; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Pyrans; Pyrroles; Vasodilation; Vasodilator Agents

1991
Pulmonary vasodilation to endothelin isopeptides in vivo is mediated by potassium channel activation.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 70, Issue:2

    Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Cats; Endothelins; Female; Guanidines; Isoproterenol; Male; Pinacidil; Potassium Channels; Pulmonary Circulation; Vasodilation

1991
Characterization of responses to cromakalim and pinacidil in smooth and cardiac muscle by use of selective antagonists.
    British journal of pharmacology, 1990, Volume: 100, Issue:2

    Topics: Animals; Aorta, Thoracic; Benzopyrans; Clonidine; Coronary Vessels; Cromakalim; Dogs; Electric Stimulation; Glyburide; Guanidines; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardial Contraction; Phentolamine; Pinacidil; Potassium Channels; Pyrroles; Rats

1990
Adrenergic-cholinergic interactions in left atria: a study using K+ channel agonists, antagonist and pertussis toxin.
    British journal of pharmacology, 1990, Volume: 99, Issue:4

    Topics: 4-Aminopyridine; Animals; Benzopyrans; Carbachol; Cromakalim; Cyclic AMP; Dogs; Female; Guanidines; Heart; Isoproterenol; Male; Myocardial Contraction; Parasympathetic Nervous System; Pertussis Toxin; Phenylephrine; Pinacidil; Potassium Channels; Pyrroles; Rabbits; Sympathetic Nervous System; Virulence Factors, Bordetella

1990
Comparison of contractions to serotonin, carbamylcholine and prostaglandin F2 alpha in rat stomach fundus.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:3

    Topics: Animals; Carbachol; Diltiazem; Dinoprost; Gastric Fundus; Guanidines; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Nitrendipine; Nitroglycerin; Phosphatidylinositols; Pinacidil; Rats; Rats, Inbred Strains; Serotonin

1989
Preserved cardiac beta-adrenergic sensitivity in early renovascular hypertension.
    Hypertension (Dallas, Tex. : 1979), 1987, Volume: 9, Issue:5

    Topics: Adenylyl Cyclases; Animals; Blood Pressure; Dogs; Guanidines; Heart Rate; Heart Ventricles; Hemodynamics; Hypertension, Renovascular; Isoproterenol; Kinetics; Male; Myocardium; Norepinephrine; Pinacidil; Receptors, Adrenergic, beta; Vasodilator Agents

1987
Pulmonary vasodilation to adrenomedullin: a novel peptide in humans.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adrenomedullin; Animals; Bronchodilator Agents; Calcitonin Gene-Related Peptide; Guanidines; Humans; In Vitro Techniques; Injections, Intra-Arterial; Isoproterenol; Male; Muscle, Smooth, Vascular; Nitroglycerin; Peptide Fragments; Peptides; Pinacidil; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vascular Resistance; Vasoconstrictor Agents; Vasodilation

1995
Involvement of K+ channels in the relaxant responses to various agonists in estrogen primed rat uterus.
    Indian journal of physiology and pharmacology, 1995, Volume: 39, Issue:2

    Topics: Animals; Benzopyrans; Calcium; Cromakalim; Dose-Response Relationship, Drug; Epinephrine; Estrogens; Female; Guanidines; Histamine; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Pinacidil; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Wistar; Uterine Contraction; Uterus; Vasodilator Agents

1995
Myogenic and agonist induced responses of coronary venules after cold hyperkalaemic cardioplegia.
    Cardiovascular research, 1995, Volume: 29, Issue:6

    Topics: Adenosine; Adenosine Diphosphate; Adrenergic beta-Agonists; Animals; Cardiopulmonary Bypass; Coronary Vessels; Endothelium, Vascular; Female; Guanidines; Heart Arrest, Induced; Isoproterenol; Male; Muscle, Smooth, Vascular; Nitroprusside; Pinacidil; Serotonin; Swine; Vasodilator Agents

1995
The effects of racemic, (+)- and (-)-pinacidil on the membrane potential of the rat aorta.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:4

    Topics: Animals; Aorta, Thoracic; Endothelium, Vascular; Glyburide; Guanidines; Isoproterenol; Male; Membrane Potentials; Pinacidil; Propanolamines; Rats; Rats, Wistar; Stereoisomerism; Vasodilator Agents

1995
Glibenclamide prevents coronary vasodilation induced by beta 1-adrenoceptor stimulation in dogs.
    The American journal of physiology, 1994, Volume: 266, Issue:1 Pt 2

    Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Bisoprolol; Coronary Circulation; Dogs; Ethanolamines; Female; Glyburide; Guanidines; Isoproterenol; Male; Myocardium; Oxygen Consumption; Pinacidil; Potassium Channels; Vasodilation; Vasodilator Agents

1994
Arteriolar tone is determined by activity of ATP-sensitive potassium channels.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 2

    Topics: Adenosine Triphosphate; Animals; Arterioles; Benzopyrans; Bucladesine; Colforsin; Cricetinae; Cromakalim; Epoprostenol; Glyburide; Guanidines; Isoproterenol; Male; Mesocricetus; Methacholine Chloride; Muscle Tonus; Muscle, Smooth, Vascular; Muscles; Nitroprusside; Pinacidil; Potassium Channels; Pyrroles; Quaternary Ammonium Compounds; Vasoconstriction; Vasodilation; Vasodilator Agents

1993
Comparative effects of continuous warm blood and intermittent cold blood cardioplegia on coronary reactivity.
    The Annals of thoracic surgery, 1997, Volume: 64, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood; Calcimycin; Colforsin; Coronary Vessels; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Guanidines; Heart Arrest, Induced; In Vitro Techniques; Isoproterenol; Microcirculation; Pinacidil; Potassium Channels; Swine; Temperature; Vasodilation; Vasodilator Agents

1997
Proarrhythmic effects of pinacidil are partially mediated through enhancement of catecholamine release in isolated perfused guinea-pig hearts.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:2

    Topics: Adenosine Triphosphate; Adrenergic Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Epinephrine; Fluoxetine; Glyburide; Guanidines; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Methoxamine; Myocardial Reperfusion Injury; Myocardium; Nadolol; Norepinephrine; Perfusion; Pinacidil; Potassium Channels; Tyramine

1998
Influence of increase in osmotic pressure with sucrose on relaxation and cyclonucleotides levels in isolated rat aorta.
    European journal of pharmacology, 1999, Oct-15, Volume: 382, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Hypertonic Solutions; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Osmotic Pressure; Pinacidil; Rats; Rats, Sprague-Dawley; Sucrose; Vasodilator Agents

1999
Investigation of the interaction between nitric oxide and vasoactive intestinal polypeptide in the guinea-pig gastric fundus.
    British journal of pharmacology, 2000, Volume: 129, Issue:4

    Topics: Adenine; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Carbachol; Colforsin; Cyclic AMP; Dexamethasone; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Isoproterenol; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Nitroprusside; Pinacidil; Tetrodotoxin; Thionucleotides; Vasoactive Intestinal Peptide

2000
Regulation of coronary myoplasmic Ca(2+)-myosin light chain phosphorylation pathway and vasomotor tone: hyperpolarizing versus depolarizing cardioplegia.
    Surgery, 2000, Volume: 128, Issue:2

    Topics: Animals; Arterioles; Calcium; Cardioplegic Solutions; Colforsin; Coronary Vessels; Heart Arrest, Induced; Hypertonic Solutions; In Vitro Techniques; Isoproterenol; Magnesium; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Phosphorylation; Pinacidil; Potassium; Rats; Rats, Sprague-Dawley

2000
Genotype-phenotype correlation in tissue models of Brugada syndrome simulating patients with sodium and calcium channelopathies.
    Heart rhythm, 2010, Volume: 7, Issue:6

    Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Body Surface Potential Mapping; Brugada Syndrome; Calcium Channel Blockers; Channelopathies; Dogs; Endocardium; Genotype; Isoproterenol; Lidocaine; Male; Pericardium; Phenotype; Pinacidil; Sodium Channels; Tissue Culture Techniques; Vasodilator Agents; Verapamil

2010
Effects of nicorandil on the cAMP-dependent Cl- current in guinea-pig ventricular cells.
    Journal of pharmacological sciences, 2010, Volume: 112, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Chloride Channels; Cyclic AMP; Glyburide; Guinea Pigs; Heart Ventricles; Hypoglycemic Agents; Isoproterenol; Nicorandil; Nitric Oxide Donors; Patch-Clamp Techniques; Pinacidil; S-Nitroso-N-Acetylpenicillamine

2010