isoproterenol and mexiletine

isoproterenol has been researched along with mexiletine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's5 (38.46)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Brown, AM; Cantù, F; Napolitano, C; Priori, SG; Schwartz, PJ1
Antzelevitch, C; Shimizu, W1
Ishii, K; Karikomi, Y; Kubota, Y; Nakahara, T; Sakamoto, K1
Cárdenas, M; Hermosillo, AG; Márquez, MF; Pastelín, G; Salica, G1
Lane, JD; Montaigne, D; Tinker, A1
Pfammatter, JP; Wåström, M1

Reviews

2 review(s) available for isoproterenol and mexiletine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug therapy in Brugada syndrome.
    Current drug targets. Cardiovascular & haematological disorders, 2005, Volume: 5, Issue:5

    Topics: Bundle-Branch Block; Cilostazol; Electrocardiography; Humans; Isoproterenol; Mexiletine; Sotalol; Syndrome; Tetrazoles

2005

Other Studies

11 other study(ies) available for isoproterenol and mexiletine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Differential response to Na+ channel blockade, beta-adrenergic stimulation, and rapid pacing in a cellular model mimicking the SCN5A and HERG defects present in the long-QT syndrome.
    Circulation research, 1996, Volume: 78, Issue:6

    Topics: Action Potentials; Animals; Cardiac Pacing, Artificial; Cation Transport Proteins; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Intercellular Signaling Peptides and Proteins; Isoproterenol; Long QT Syndrome; Mexiletine; Mutation; Peptides; Phenethylamines; Potassium Channels; Potassium Channels, Voltage-Gated; Receptors, Adrenergic, beta; Sodium Channel Blockers; Sodium Channels; Sulfonamides

1996
Cellular basis for the ECG features of the LQT1 form of the long-QT syndrome: effects of beta-adrenergic agonists and antagonists and sodium channel blockers on transmural dispersion of repolarization and torsade de pointes.
    Circulation, 1998, Nov-24, Volume: 98, Issue:21

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Isoproterenol; KCNQ Potassium Channels; Long QT Syndrome; Membrane Potentials; Mexiletine; Perfusion; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Sodium Channel Blockers; Torsades de Pointes

1998
Characterization of mexiletine as an antagonist of beta-adrenoceptor in Chinese hamster ovary cells expressing cloned human beta-adrenoceptors.
    Biochemical pharmacology, 2004, Mar-01, Volume: 67, Issue:5

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Binding, Competitive; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Drug Interactions; Female; Humans; Iodine Radioisotopes; Isoproterenol; Kinetics; Lidocaine; Mexiletine; Pindolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Transfection

2004
Tissue-Level Cardiac Electrophysiology Studied in Murine Myocardium Using a Microelectrode Array: Autonomic and Thermal Modulation.
    The Journal of membrane biology, 2017, Volume: 250, Issue:5

    Topics: Animals; Atrial Function; Carbachol; Electrophysiologic Techniques, Cardiac; Electrophysiological Phenomena; Female; Heart Atria; Heart Ventricles; Isoproterenol; Male; Mexiletine; Mice; Microelectrodes; Myocardium; Ventricular Function

2017
Ten-year-old boy with congenital long QT syndrome type 2 (LQTS2) and life-threatening electrical storm: a case report of successful treatment with mexiletine.
    Cardiology in the young, 2022, Volume: 32, Issue:11

    Topics: Arrhythmias, Cardiac; Humans; Isoproterenol; Long QT Syndrome; Male; Mexiletine; Ventricular Fibrillation

2022