isoproterenol has been researched along with metoprolol in 197 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 87 (44.16) | 18.7374 |
| 1990's | 51 (25.89) | 18.2507 |
| 2000's | 37 (18.78) | 29.6817 |
| 2010's | 22 (11.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Hoffmann, C; Klotz, KN; Leitz, MR; Lohse, MJ; Oberdorf-Maass, S | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Charlton, SJ; Dickson, CJ; Duca, JS; Fairhurst, RA; Hornak, V; McKay, DJ; Pearlstein, RA; Reilly, J; Sandham, DA; Shaw, D; Sykes, DA; Velez-Vega, C | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Boorsma, M; Meems, L; Zaagsma, J | 1 |
| Gooren, L; Harms, HH; Hesse, C; Spoelstra, AJ; Verschoor, L | 1 |
| Ahlman, H; Dahlström, A; Kewenter, J; Larsson, I; Lundberg, JM; Pettersson, G | 1 |
| Aberg, G; Arfwidsson, I | 1 |
| Aberg, G; Adler, G; Wikberg, J | 1 |
| Carlsson, E; Herrmann, I; Lundgren, B | 1 |
| Fredén, K; Kutti, J; Lundborg, P; Olsson, LB; Vilén, L | 1 |
| Boden, G; Gugler, R; Höffgen, K; Krist, R; Raczinski, H | 1 |
| Kittel, E; Philippu, A | 1 |
| Malchoff, CD; Marinetti, GV | 1 |
| Björntorp, P; Fellenius, E; Smith, U; William-Olsson, T | 1 |
| Clement, DL | 1 |
| Sinclair, DJ | 1 |
| Hida, W; Mue, S; Ohmi, T; Sasaki, T; Shibahara, S; Suzuki, S; Takahashi, M; Takishima, T; Yamauchi, K | 1 |
| Bourdillon, PD; Canepa-Anson, R; Rickards, AF | 1 |
| Hatano, Y; Hayashi, S; Miyazaki, M; Okunishi, H; Toda, N | 1 |
| Bottermann, P; Klein, G; Schinz, A; Schnelle, A; Zilker, T | 1 |
| Van Petten, GR | 1 |
| Akhtar, M; Avitall, B; Jazayeri, MR; Murthy, VS; Shen, YH; Sra, JS; Troup, PJ | 1 |
| Okuma, Y; Osumi, Y; Yokotani, K | 1 |
| Ayajiki, K; Toda, N | 1 |
| Iwabuchi, Y; Masuhara, T | 1 |
| Doggrell, SA; Surman, AJ | 1 |
| Jungermann, K; Püschel, GP; Ulken, V | 1 |
| Dagher, G; Sauterey, C | 1 |
| Guillet, JG; Hjalmarson, A; Hoebeke, J; Magnusson, Y; Wallukat, G | 1 |
| Mills, RG; Roberts, MS; Shen, JJ; Wanwimolruk, S | 1 |
| Chiba, S; Tsukada, M | 1 |
| Chang, PI; Rutlen, DL | 1 |
| de Moraes, S; Spadari, RC | 2 |
| Bedi, GS | 1 |
| Doggrell, SA | 4 |
| Hearse, DJ; Tosaki, A; Woodward, B; Yamamoto, F | 1 |
| Akhtar, M; Anderson, AJ; Avitall, B; Gal, R; Jazayeri, MR; Shalev, Y; Tchou, PJ | 1 |
| Barr, SM; Cobbe, SM; Manley, BS | 1 |
| Paull, JD; Ziccone, SP | 1 |
| Andersson, KE; Forman, A; Madsen, G; Tøttrup, A | 1 |
| Wu, S | 1 |
| Fraeyman, N; Van de Velde, E; Vanscheeuwijck, P | 1 |
| Armstrong, DT; Calaresu, FR; Morley, P | 1 |
| Huber, I; Stäblein, A; von Scheidt, W | 1 |
| Okamura, T; Toda, N | 1 |
| Beil, ME; Cabot, CF; Coram, WM; Olson, RW; Weiss, GB | 1 |
| Hunt, GB; Ross, DL | 1 |
| Egan, TM; Noble, D; Noble, SJ; Powell, T; Twist, VW; Yamaoka, K | 1 |
| Blasucci, DJ; Chodosh, S; Tuck, J | 1 |
| Elsner, D; Kromer, EP; Riegger, AJ | 1 |
| Mason, R; Walker, G; Winslow, E | 1 |
| Koshiura, R; Miyamoto, K; Sanae, F | 1 |
| Borst, HG; Brodde, OE; Maier, W; Michel, MC; Zerkowski, HR | 1 |
| Conroy, WG; Isom, GE; Peoples, RW | 1 |
| Acuña, D; Castillo, MA; García-Torres, L; Haro, JM; Vargas, F | 1 |
| Cardozo, L; Rutledge, DR; Steinberg, J | 1 |
| Palkama, A; Raij, K; Uusitalo, H; Uusitalo, R | 1 |
| Gurll, NJ; Lechner, RB; Reynolds, DG | 1 |
| Bjellin, LA; Ek, BA; Lundgren, BT | 1 |
| Kopia, GA; Ruffolo, RR | 1 |
| Tattersfield, AE; Thomas, MS | 1 |
| Antonaccio, MJ; DeForrest, JM; High, J; Sybertz, E | 1 |
| Bevan, JA; McPherson, GA | 1 |
| Croughwell, N; de Bruijn, N; Knopes, K; Reves, JG | 1 |
| Nathanson, JA | 1 |
| Dousa, TP; Gapstur, SM; Murayama, N; Ruggles, BT; Werness, JL | 1 |
| Kondo, S; Morita, T; Tsuchida, S; Weiss, RM | 1 |
| Chakravarti, S; Kulkarni, SK; Parale, MP | 1 |
| Gabry, AL; Hoang, TD; Lapandry, C; Pourriat, JL | 1 |
| Myrdal, S; Rabkin, SW; Sunga, P | 1 |
| Constantin, L; Martins, JB | 1 |
| Collett, AR; Rand, MJ; Story, DF | 1 |
| Boucher, M; Dubray, C; Duchene-Marullaz, P | 1 |
| Potter, DE; Rowland, JM | 1 |
| Ljung, O | 1 |
| Ablad, B; Dahlöf, C; Ljung, B | 1 |
| Giorgetti, F; Re, L; Rossini, L | 1 |
| Re, L; Rossini, L | 1 |
| Ahrén, B; Lundquist, I | 1 |
| Brenner, GM; Wulf, RG | 1 |
| Folgering, H | 1 |
| Coltart, DJ; Hearse, DJ; Manning, AS; Yellon, DM | 1 |
| Ek, B; Lundgren, B | 1 |
| Dahlöf, C | 1 |
| Bonelli, J | 1 |
| Boomsma, F; Man in't Veld, AJ; Schalekamp, MA | 1 |
| Carlsson, E; Hedberg, A; Mattsson, H | 1 |
| Brandi, ML; Rotella, CM; Toccafondi, RS; Zonefrati, R | 1 |
| Anlauf, M; Bock, KD; Brodde, OE; Weber, F | 1 |
| Higginson, LM; Opie, LH; Thandroyen, FT; Worthington, MG | 1 |
| Aars, H | 1 |
| Teräväinen, H | 1 |
| Knudtzon, J | 1 |
| Anakwe, OO; Moger, WH | 1 |
| Dahlström, U; Nylander, E | 1 |
| Ahmad, D; Carruthers, SG; Clague, HW | 1 |
| Baumann, G; Blömer, H; Blümel, G; Erhardt, WD; Felix, SB; Ludwig, L; Riess, G | 1 |
| Baumann, G; Blömer, H; Erhardt, WD; Felix, SB; Heidecke, CD; Loher, U; Ludwig, L; Riess, G; Schrader, J; Sebening, F | 1 |
| Maggi, CA; Meli, A | 1 |
| Bleasdale, JE; Di Renzo, GC; Venincasa, MD | 1 |
| Luca, C; Marchini, F; Usardi, MM | 1 |
| D'Avella, J; DeFronzo, RA; Katz, LD | 1 |
| Kalbfleisch, JH; Kolesari, GL; Kuhlmann, RS | 1 |
| Condorelli, M; Cuocolo, A; De Luca, N; Ricciardelli, B; Trimarco, B; Veniero, AM; Volpe, M | 1 |
| Huerta, FI; Sharma, AD; Waxman, MB | 1 |
| Barker, NP; Ellis, ME; Fitzsimons, TJ; Hussain, M; Webb, AK | 1 |
| Cornish, KG; Gorman, AJ; Holmberg, MJ; Zucker, IH | 1 |
| Langlois, S; Lutterodt, A; Rangno, RE | 1 |
| Langlois, S; Rangno, RE; Stewart, J | 1 |
| Langlois, S; Rangno, RE | 1 |
| Kohlschütter, S; Lang, E; Schiess, W; Szécsi, E | 1 |
| Boström, S; Hansson, G; Risberg, B; Rydholm, H | 1 |
| Abe, H; Izumi, F; Kobayashi, H; Kuroiwa, A; Nakashima, Y | 2 |
| Hasegawa, S; Imai, S; Kanda, T; Kobayashi, I; Ma, H; Matsuzaki, S; Nakano, M; Suzuki, T | 1 |
| Jaeger, R; Jorde, R; Sager, G; Trovik, TS | 2 |
| Maev, IV; Merzlikin, LA; V'iuchnova, ES | 1 |
| Arner, P; Enocksson, S; Lönnqvist, F; Nordenström, J; Shimizu, M | 1 |
| Dahl, D; Li, J | 2 |
| Irlbeck, M; Zimmer, HG | 1 |
| Toews, ML; Zhu, SJ | 2 |
| Corcoran, ME; Jones, SJ; Kirkby, RD; Pelletier, MR | 1 |
| MacLellan-Tobert, SG; O'Marcaigh, AS; Porter, CJ | 1 |
| Cherng, WJ; Hood, WB; Liang, CS | 1 |
| Bassani, JW; Bassani, RA | 1 |
| Campos Peris, JV; de la Morena, G; García García, J; Jaén Armand, E; López Candel, J; Martínez Sánchez, J; Picó Aracil, F; Ruiz Ros, JA; Salas, J; Sánchez Muñoz, JJ | 1 |
| Ijzerman, AP; Krasel, C; Lohse, MJ; Wieland, K; Zuurmond, HM | 1 |
| Akhtar, M; Dhala, A; Natale, A; Newby, KH; Sra, J | 1 |
| Smith, W | 1 |
| Berthelsen, PG; Lippert, FK; Yndgaard, S | 1 |
| Iwabuchi, Y; Kimura, T | 1 |
| DiBona, GF; Sawin, LL | 1 |
| Abe, I; Fujii, K; Fujishima, M; Goto, K; Onaka, U | 1 |
| Farias-Silva, E; Grassi-Kassisse, DM; Spadari-Bratfisch, RC; Wolf-Nunes, V | 1 |
| Chandrasekar, B; Freeman, GL; Murray, DR; Prabhu, SD | 1 |
| Brodsky, C; Vlay, LC; Vlay, SC | 1 |
| Carneiro, SM; Markus, RP; Scrivano, CN; Yamanouye, N | 1 |
| Amsterdam, A; Dantes, A; Selvaraj, N | 1 |
| Böhm, M; Cremers, B; Ettelbrück, S; Flesch, M; Maack, C; Rosenkranz, S; Schlüter, KD; Zolk, O | 1 |
| Baumann, G; Felix, SB; Fu, M; Grosse, Y; Mobini, R; Stangl, K; Stangl, V; Staudt, A; Thiele, A | 1 |
| Bölck, B; Brixius, K; Bundkirchen, A; Mehlhorn, U; Schwinger, RH | 1 |
| Aki, T; Hatanaka, K; Senba, E; Ueyama, T; Yoshida, K | 1 |
| Doverspike, A; Hentosz, T; Huerbin, R; Nikolaidis, LA; Shannon, RP; Shen, YT; Stolarski, C | 1 |
| Andrews, RD; Elliott, NM; Jones, DR | 1 |
| Felix, SB; Fu, M; Kühn, JP; Mobini, R; Staudt, A; Staudt, Y | 1 |
| Kimura, Y; Morisawa, M; Yoshida, M | 1 |
| Bölck, B; Brixius, K; Bundkirchen, A; Mehlhorn, U; Nguyen, Q; Schwinger, RH | 1 |
| Höcht, C; Opezzo, JA; Taira, CA | 1 |
| Chase, EG; Minami, E; Murry, CE; Rossow, CF; Santana, LF | 1 |
| Bauer, I; Bauer, M; Kubulus, D; Rensing, H; Winning, J; Wolf, B; Ziegeler, S | 1 |
| Böhm, M; Finkler, N; Kindermann, M; Läer, S; Maack, C; Schäfers, HJ; Schaller, S; Schmidt, KI; Wuttke, H | 1 |
| Jung, S; Jung, Y; Kang, S; Lee, S; Park, H | 1 |
| Knuepfer, MM; Rauls, RA; Tan, Y | 1 |
| Chen, SR; Davidoff, AW; Mei, J; Obayashi, M; Stuyvers, BD; ter Keurs, HE; Xiao, B | 1 |
| Magovern, M; Nikolaidis, LA; Parikh, P; Poornima, I; Shannon, RP; Shen, YT | 1 |
| Bader, M; Baltatu, OC; Campos, LA; Fontes, MA; Iliescu, R; Schlegel, WP | 1 |
| Mader, SL; Reed, JF; Schutzer, WE; Xue, H | 1 |
| Diwu, Z; Han, X; Li, X; Lu, J; Tang, Y | 1 |
| Attademo, A; Baiardi, G; Celis, ME; Sánchez-Borzone, ME | 1 |
| Esposito, G; Ferrara, N; Filippelli, A; Fortunato, F; Golino, L; Iaccarino, G; Koch, WJ; Leosco, D; Lymperopoulos, A; Marchese, M; Rapacciuolo, A; Rengo, F; Rengo, G; Rinaldi, B; Zincarelli, C | 1 |
| Chen, PC; Huang, CC; Huang, CW; Yu, J | 1 |
| Baeyens, WR; De Beer, T; Dilinuer, M; Fei, GT; Ouyang, J; Wang, Y; Zhou, S | 1 |
| Asari, K; Hanada, K; Kawana, J; Mita, M; Ogata, H; Saito, M | 1 |
| Dell'Italia, LJ; Denney, T; Dillon, AR; Killingsworth, C; Pat, B; Powell, P; Tillson, M; Zheng, J | 1 |
| Boralli, VB; Danhof, M; de Lange, EC; Freijer, J; Krekels, EH; Slijkerman, P; van Steeg, TJ | 1 |
| Gizak, A; Rakus, D; Zarzycki, M | 1 |
| Geduhn, J; Gille, A; Göttle, M; Höcherl, K; König, B; Seifert, R | 1 |
| de Beer, VJ; Duncker, DJ; Gao, F; Hoekstra, M; Merkus, D; Xiao, C | 1 |
| Blanke, K; Dhein, S; Janousek, J; Salameh, A | 1 |
| Bányász, T; Bárándi, L; Harmati, G; Horváth, B; Magyar, J; Nánási, PP; Szabó, G; Szénási, G; Szentandrássy, N; Szentmiklósi, JA | 1 |
| Boyko, M; Dubilet, M; Gruenbaum, BF; Gruenbaum, SE; Klin, Y; Kotz, R; Leibowitz, A; Ohayon, S; Shapira, Y; Teichberg, VI; Zlotnik, A | 1 |
| Böhm, M; Caglayan, E; Ghanem, A; Gross, ML; Huntgeburth, M; Mödersheim, S; Müller-Ehmsen, J; Rosenkranz, S; Schlüter, KD; Schreckenberg, R; Shahverdyan, R; Tiemann, K; Vantler, M; Zimmermann, WH | 1 |
| Ge, J; Goldstein, S; He, B; Li, Y; Ruiz, G; Zhang, M; Zhang, S | 1 |
| Cao, J; Du, Y; Han, X; Li, X; Liu, H; Song, K; Wang, J; Yan, L; Zhan, W | 1 |
| Altan, VM; Arioglu-Inan, E; Balligand, JL; Esfahani, H; Kayki-Mutlu, G; Ozakca, I; Ozcelikay, AT | 1 |
| Szulczyk, B | 2 |
| Denkaew, T; Mangmool, S; Nishida, M; Parichatikanond, W; Phosri, S; Pinthong, D; Shimauchi, T | 1 |
| Acimovic, I; Dvorak, P; Jelinkova, S; Lacampagne, A; Meli, AC; Pesl, M; Pribyl, J; Rotrekl, V; Salykin, A; Skladal, P; Vilotic, A | 1 |
| Bahrainy, S; Busey, JM; Caldwell, JH; Levy, WC; Stratton, JR | 1 |
| Ehmke, H; Jelinek, M; Schwoerer, AP; Wallach, C | 1 |
| Khwaja, S; Mahmood, T; Siddiqui, HH | 1 |
| Li, X; Liu, X; Qi, C; Shao, Y; Wang, D | 1 |
2 review(s) available for isoproterenol and metoprolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Importance of receptor regulation in the pathophysiology and therapy of congestive heart failure.
Topics: Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Disease Models, Animal; Dobutamine; Dogs; Guinea Pigs; Heart Failure; Heart Rate; Heart Ventricles; Humans; Isoproterenol; Metoprolol; Myocardial Contraction; Norepinephrine; Propranolol; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Glucagon; Receptors, Histamine H2 | 1986 |
16 trial(s) available for isoproterenol and metoprolol
| Article | Year |
|---|---|
Beta-adrenoceptor blocking drugs at maximum beta-blockade in relation to dose and plasma concentration.
Topics: Adrenergic beta-Antagonists; Adult; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Pindolol; Propranolol | 1979 |
Differences in metabolic responses to beta-adrenergic stimulation after propranolol or metoprolol administration.
Topics: Adult; Blood Glucose; Fatty Acids, Nonesterified; Glycerol; Hemodynamics; Humans; Insulin; Isoproterenol; Male; Metoprolol; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sodium Chloride; Terbutaline | 1979 |
Effect of selective and non-selective beta-adrenoreceptor blockade on calf blood flow in hypertensive patients.
Topics: Blood Pressure; Heart Rate; Humans; Hypertension; Isoproterenol; Leg; Metoprolol; Propanolamines; Propranolol | 1978 |
Comparison of effects of propranolol and metoprolol on airways obstruction in chronic bronchitis.
Topics: Airway Obstruction; Bronchitis; Clinical Trials as Topic; Double-Blind Method; Forced Expiratory Volume; Humans; Isoproterenol; Metoprolol; Middle Aged; Propanolamines; Propranolol; Random Allocation; Vital Capacity | 1979 |
Influence of metoprolol on hemodynamics and respiratory function in asthmatic patients.
Topics: Asthma; Double-Blind Method; Female; Hemodynamics; Humans; Isoproterenol; Male; Metoprolol; Placebos; Propanolamines; Respiration; Time Factors | 1979 |
The effects of dilevalol, metoprolol, and placebo on ventilatory function in asthmatics.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Asthma; Female; Forced Expiratory Volume; Hemodynamics; Humans; Isoproterenol; Labetalol; Male; Metoprolol; Middle Aged; Respiratory Function Tests | 1988 |
Racial differences in drug response: isoproterenol effects on heart rate following intravenous metoprolol.
Topics: Adult; Drug Antagonism; Half-Life; Heart Rate; Humans; Isoproterenol; Male; Metabolic Clearance Rate; Metoprolol; Racial Groups; Random Allocation; Statistics as Topic | 1989 |
Comparison of beta-adrenoceptor selectivity of acebutolol and its metabolite diacetolol with metoprolol and propranolol in normal man.
Topics: Acebutolol; Adrenergic beta-Antagonists; Airway Resistance; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Metoprolol; Physical Exertion; Propranolol; Receptors, Adrenergic, beta | 1986 |
Influence of cardioselectivity and respiratory disease on pulmonary responsiveness to beta-blockade.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Asthma; Bronchitis; Female; Heart; Humans; Isoproterenol; Lung; Lung Diseases, Obstructive; Male; Metoprolol; Middle Aged; Propranolol; Respiratory Function Tests | 1984 |
Comparison of withdrawal phenomena after propranolol, metoprolol, and pindolol.
Topics: Adult; Aged; Blood Pressure; Heart Rate; Humans; Hypertension; Isoproterenol; Metoprolol; Middle Aged; Pindolol; Propanolamines; Propranolol; Substance Withdrawal Syndrome | 1982 |
Abrupt withdrawal of pindolol or metoprolol after chronic therapy.
Topics: Adult; Blood Pressure; Drug Hypersensitivity; Electrocardiography; Female; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Physical Exertion; Pindolol; Propanolamines; Substance Withdrawal Syndrome; Time Factors | 1982 |
Reduced beta-adrenergic sensitivity in healthy volunteers induced by hypoglycemia.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Humans; Hypoglycemia; Insulin; Isoproterenol; Male; Metoprolol; Receptors, Adrenergic, beta; Sodium Chloride | 1995 |
Reduced sensitivity to beta-adrenoceptor stimulation and blockade in insulin dependent diabetic patients with hypoglycaemia unawareness.
Topics: Adult; Analysis of Variance; Awareness; Blood Glucose; Blood Pressure; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Epinephrine; Female; Heart Rate; Hemoglobins; Humans; Hypoglycemia; Injections, Intravenous; Isoproterenol; Male; Metoprolol; Norepinephrine; Receptors, Adrenergic, beta; Regression Analysis | 1994 |
Effects of beta-adrenergic blockade on vasodepressor reaction in patients with vasodepressor syncope.
Topics: Epinephrine; Erythrocyte Membrane; Female; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Norepinephrine; Posture; Propranolol; Receptors, Adrenergic, beta; Sympathetic Nervous System; Syncope; Tilt-Table Test | 1994 |
[Do cardioselective beta-antagonists block the cardiac beta-receptor function also in the long run?].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Bisoprolol; Cardiotonic Agents; Hemodynamics; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Receptors, Adrenergic, beta; Time Factors | 1998 |
Carvedilol but not metoprolol reduces beta-adrenergic responsiveness after complete elimination from plasma in vivo.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Alleles; Allosteric Site; Binding Sites; Carbazoles; Cardiac Output; Carvedilol; Cross-Over Studies; Cytochrome P-450 CYP2D6; Dobutamine; Echocardiography, Stress; Genotype; Heart Atria; Heart Rate; Humans; Inactivation, Metabolic; Isoproterenol; Male; Metoprolol; Propanolamines; Protein Binding; Receptors, Adrenergic, beta; Up-Regulation | 2004 |
179 other study(ies) available for isoproterenol and metoprolol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Humans; Radioligand Assay; Receptors, Adrenergic, beta; Transfection | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Uncoupling the Structure-Activity Relationships of β2 Adrenergic Receptor Ligands from Membrane Binding.
Topics: Binding Sites; Cell Membrane; Dose-Response Relationship, Drug; Humans; Ligands; Models, Molecular; Molecular Structure; Receptors, Adrenergic, beta-2; Structure-Activity Relationship | 2016 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Beta-Adrenoceptor studies. 4. Influence of albumin on in vitro beta-adrenoceptor blocking and antiarrhythmic properties of propranolol, pindolol, practolol and metoprolol.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ouabain; Pindolol; Practolol; Propanolamines; Propranolol; Protein Binding; Serum Albumin, Bovine; Trachea | 1977 |
Blockade of isoprenaline-induced changes in plasma free fatty acids, immunoreactive insulin levels and plasma renin activity in healthy human subjects, by propranolol, pindolol, practolol, atenolol, metoprolol and acebutolol.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Fatty Acids, Nonesterified; Heart Rate; Humans; Insulin; Isoproterenol; Male; Metoprolol; Pindolol; Practolol; Propranolol; Renin | 1978 |
The release of serotonin from rat duodenal enterochromaffin cells by adrenoceptor agonists studied in vitro.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Chromaffin System; Dopamine; Duodenum; Enterochromaffin Cells; Epinephrine; Isoproterenol; Male; Metoprolol; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Serotonin | 1978 |
Haemodynamic effects of the quaternary ammonium compound QX 572 in anaesthetized cats. III. Interactions with adrenergic beta-adrenoceptor blockade.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cats; Drug Interactions; Female; Heart Rate; Isoproterenol; Male; Metoprolol; Quaternary Ammonium Compounds; Sodium Chloride | 1979 |
Inhibition and facilitation of lacrimal flow by beta-adrenergic drugs.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cholinergic Fibers; Electric Stimulation; Heart Rate; Isoproterenol; Lacrimal Apparatus; Metoprolol; Organ Culture Techniques; Propranolol; Rabbits; Receptors, Adrenergic, beta; Secretory Rate; Sodium Chloride; Tears | 1979 |
Beta-adrenoceptor blockade by atenolol, metoprolol and propranolol in the anaesthetized cat.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Atenolol; Cats; Female; Heart Rate; Hemodynamics; Hindlimb; Isoproterenol; Male; Metoprolol; Muscle Relaxation; Propanolamines; Propranolol; Regional Blood Flow; Vasodilation | 1979 |
The peripheral platelet count and the isoprenaline-induced splenic platelet pooling in response to beta-adrenoceptor blockade.
Topics: Adrenergic beta-Antagonists; Adult; Blood Platelets; Female; Heart Rate; Hematocrit; Humans; Isoproterenol; Male; Metoprolol; Platelet Count; Propranolol; Spleen | 1979 |
Presence of beta-adrenoreceptors in the hypothalamus; their importance for the pressor response to hypothalamic stimulation.
Topics: Animals; Blood Pressure; Catheterization; Cats; Drug Interactions; Electric Stimulation; Female; Hypothalamus; Isoproterenol; Male; Metoprolol; Practolol; Procaine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sotalol; Stereoisomerism; Tolazoline | 1977 |
Hormone action at the membrane level. VI. Binding of (-)-[3H]dihydroalprenolol and (+/-)-[3H]isoproterenol to turkey erythrocytes and correlation with adenylate cyclase activity.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Binding Sites; Epinephrine; Erythrocyte Membrane; Erythrocytes; Ethanolamines; Female; Isoproterenol; Metoprolol; Norepinephrine; Practolol; Propranolol; Receptors, Adrenergic, beta; Stereoisomerism; Turkeys | 1978 |
Hemodynamic effects of intravenous metoprolol.
Topics: Adult; Cardiac Catheterization; Cardiac Pacing, Artificial; Drug Evaluation; Female; Heart; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Isoproterenol; Male; Metoprolol; Middle Aged; Myocardial Contraction; Propanolamines; Stroke Volume; Vascular Resistance | 1979 |
Selectivity and steric effects of metoprolol isomers on isolated rabbit atria, arteries and tracheal muscles.
Topics: Animals; Arteries; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Propanolamines; Propranolol; Rabbits; Species Specificity; Stimulation, Chemical; Trachea | 1978 |
[Effects of metoprolol and alprenolol on the carbohydrate and lipid metabolism during beta adrenergic stimulation with isoproterenol in the normal subject].
Topics: Alprenolol; Carbohydrate Metabolism; Humans; Isoproterenol; Lipid Metabolism; Metoprolol; Propanolamines; Stimulation, Chemical | 1978 |
Cardiovascular effects of metoprolol in the pregnant ewe and fetus.
Topics: Animals; Female; Fetus; Heart Rate; Hemodynamics; Isoproterenol; Metoprolol; Pregnancy; Pregnancy, Animal; Propanolamines; Sheep; Stimulation, Chemical; Time Factors | 1976 |
Use of intravenous esmolol to predict efficacy of oral beta-adrenergic blocker therapy in patients with neurocardiogenic syncope.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Female; Humans; Hypotension, Orthostatic; Isoproterenol; Male; Metoprolol; Posture; Predictive Value of Tests; Propanolamines; Syncope | 1992 |
Release of endogenous noradrenaline from the vascularly perfused rat stomach in vitro: modulation by pre- and postsynaptic adrenoceptors.
Topics: Animals; Butoxamine; Calcium; Chromatography, High Pressure Liquid; Clonidine; Electric Stimulation; Ganglionic Blockers; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Metoprolol; Norepinephrine; Perfusion; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Splanchnic Nerves; Stomach; Tetrodotoxin; Yohimbine | 1992 |
Regional difference in the response mediated by beta 1-adrenoceptor subtype in bovine cerebral arteries.
Topics: Adrenergic beta-Agonists; Animals; Cattle; Cerebral Arteries; Colforsin; Dose-Response Relationship, Drug; Homeostasis; Isoproterenol; Metoprolol; Norepinephrine; Receptors, Adrenergic, beta; Terbutaline | 1992 |
Effects of cholinergic and adrenergic agonists on the secretion of fluid and protein by submandibular glands of the hamster and the rat.
Topics: Animals; Cricetinae; Isoproterenol; Male; Mesocricetus; Metoprolol; Parasympathomimetics; Phenylephrine; Pilocarpine; Piperidines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cholinergic; Saliva; Salivary Proteins and Peptides; Submandibular Gland; Sympathomimetics | 1992 |
Characterization of the antagonism with metoprolol, ICI 147,798, pindolol, mepindolol and bopindolol on the responses of the rat left atria to isoprenaline.
Topics: Adrenergic beta-Antagonists; Animals; Heart; Isoproterenol; Male; Metoprolol; Myocardial Contraction; Pindolol; Pyrazines; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1992 |
Increase in glucose and lactate output and perfusion resistance by stimulation of hepatic nerves in isolated perfused rat liver: role of alpha 1-, alpha 2-, beta 1- and beta 2-receptors.
Topics: Animals; Butoxamine; Electric Stimulation; Glucose; Hemodynamics; Isoproterenol; Kinetics; Lactates; Liver; Male; Metoprolol; Norepinephrine; Perfusion; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1991 |
Regulation of intracellular pH in rabbit cortical connecting tubule and cortical collecting duct.
Topics: Acid-Base Equilibrium; Ammonium Chloride; Animals; Biological Transport; Cations; Cyclic AMP; Ethylmaleimide; Fluoresceins; Homeostasis; Hydrogen-Ion Concentration; Isoproterenol; Kidney Cortex; Kidney Tubules; Kinetics; Male; Metoprolol; Protons; Rabbits; Sodium | 1991 |
Functional analysis of rabbit anti-peptide antibodies which mimic autoantibodies against the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy.
Topics: Amino Acid Sequence; Animals; Autoantibodies; Binding Sites; Binding, Competitive; Cardiomyopathy, Hypertrophic; Dose-Response Relationship, Immunologic; Glioma; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Isoproterenol; Magnesium; Metoprolol; Molecular Sequence Data; Pindolol; Rabbits; Radioligand Assay; Receptors, Adrenergic, beta | 1991 |
Response to beta-blockers in maternal and fetal rat hearts in vitro.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Female; Heart; Heart Rate; Isoproterenol; Labetalol; Metoprolol; Pregnancy; Pregnancy, Animal; Propranolol; Rats; Rats, Inbred Strains | 1991 |
Evidence for the existence of postsynaptic beta-1 and beta-2 adrenoceptors in isolated simian facial veins.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Dobutamine; Ethanolamines; Face; Female; Isoproterenol; Macaca; Male; Metoprolol; Muscle, Smooth, Vascular; Norepinephrine; Procaterol; Propanolamines; Receptors, Adrenergic, beta; Synapses; Synaptic Transmission; Vasodilation; Veins | 1991 |
Effects of beta-adrenergic agonists on splanchnic vascular volume and cardiac output.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Blood Volume; Cardiac Output; Denervation; Dogs; Female; Heart Rate; Isoproterenol; Male; Metoprolol; Muscle, Smooth, Vascular; Phenoxybenzamine; Pressoreceptors; Receptors, Adrenergic, beta; Splanchnic Circulation; Splenectomy; Terbutaline | 1991 |
Subsensitivity to beta-adrenoceptor agonists in pacemakers isolated from senescent rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; Cocaine; Ethanolamines; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Norepinephrine; Oxidopamine; Phenoxybenzamine; Rats; Rats, Inbred Strains | 1991 |
The effect of adrenergic agonists and antagonists on cysteine-proteinase inhibitor (cystatin) in rat saliva.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Blotting, Western; Cysteine Proteinase Inhibitors; Dobutamine; Electrophoresis, Polyacrylamide Gel; Female; Isoproterenol; Methamphetamine; Methoxamine; Metoprolol; Norepinephrine; Propanolamines; Propranolol; Radioimmunoassay; Rats; Rats, Inbred Strains; Salivary Proteins and Peptides; Terbutaline | 1991 |
Effects of (+/-)- (+)- and (-)-metoprolol, (+/-)- (+)- and (-)-pindolol, (+/-)-mepindolol and (+/-)-bopindolol on the rat left atria and portal vein.
Topics: Adrenergic beta-Antagonists; Animals; Atrial Function, Left; Electric Stimulation; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Muscle, Smooth, Vascular; Myocardial Contraction; Pindolol; Portal Vein; Rats; Rats, Inbred Strains; Stereoisomerism | 1991 |
Isoproterenol and the genesis of reperfusion-induced arrhythmias in isolated rat heart: adrenoceptor or free radical-mediated mechanisms?
Topics: Animals; Antioxidants; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Dose-Response Relationship, Drug; Electric Stimulation; Electrocardiography; Free Radicals; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Myocardial Reperfusion; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Stereoisomerism | 1990 |
Echocardiographic demonstration of decreased left ventricular dimensions and vigorous myocardial contraction during syncope induced by head-up tilt.
Topics: Adult; Echocardiography; Female; Humans; Isoproterenol; Male; Metoprolol; Myocardial Contraction; Posture; Syncope; Ventricular Function, Left | 1991 |
Metoprolol and ventricular repolarisation and refractoriness: lack of chronic adaptational class III effects in rabbit.
Topics: Animals; Disease Models, Animal; Electrophysiology; Epinephrine; Heart; Isoproterenol; Male; Metoprolol; Pacemaker, Artificial; Rabbits; Stress, Physiological | 1991 |
The actions of tulobuterol on isolated preparations of gravid human myometrium.
Topics: Adrenergic beta-Agonists; Electric Stimulation; Epinephrine; Female; Humans; In Vitro Techniques; Isoproterenol; Metoprolol; Molecular Structure; Pregnancy; Terbutaline; Uterine Contraction | 1990 |
The actions of some beta-receptor agonists and xanthines on isolated muscle strips from the human oesophago-gastric junction.
Topics: Adenosine; Adrenergic beta-Agonists; Adult; Aged; Dobutamine; Dose-Response Relationship, Drug; Esophagogastric Junction; Female; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Tetrodotoxin; Xanthines | 1990 |
[Beta-receptor blocking effect in human by propranolol and metoprolol].
Topics: Adult; Female; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Propranolol | 1990 |
The beta-adrenergic transduction system in kidneys from young and senescent rats.
Topics: Adenylyl Cyclase Inhibitors; Aging; Animals; Cyclic AMP; Guanylyl Imidodiphosphate; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Kidney; Kinetics; Male; Membranes; Metoprolol; Pindolol; Propanolamines; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Signal Transduction | 1990 |
Assessment of the beta 2 adrenoceptor and Ca2+ channel-blocking activity of drugs with the rat portal vein.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dobutamine; Isoproterenol; Male; Metoprolol; Muscle Contraction; Portal Vein; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Verapamil | 1990 |
Catecholamines inhibit steroidogenesis by cultured porcine thecal cells.
Topics: Androstenedione; Animals; Catechol O-Methyltransferase Inhibitors; Catecholamines; Female; Isoproterenol; Luteinizing Hormone; Metoprolol; Propiophenones; Swine; Theca Cells | 1990 |
[Life threatening syncope in a 69-year-old male: syndrome of hyperactive parasympathetic counter-regulation].
Topics: Aged; Cardiomyopathy, Hypertrophic; Cerebral Hemorrhage; Hemodynamics; Homeostasis; Humans; Isoproterenol; Male; Metoprolol; Parasympathetic Nervous System; Recurrence; Sympathetic Nervous System; Syncope | 1990 |
Beta adrenoceptor subtype in isolated human, monkey and dog epicardial coronary arteries.
Topics: Animals; Butoxamine; Coronary Vessels; Dogs; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Humans; Isoproterenol; Macaca; Male; Mesenteric Arteries; Metoprolol; Muscle, Smooth, Vascular; Rabbits; Receptors, Adrenergic; Renal Artery; Species Specificity | 1990 |
Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol.
Topics: Animals; Atenolol; Differential Threshold; Dogs; Drug Combinations; Isoproterenol; Lidocaine; Metoprolol; Myocardial Contraction; Pindolol; Propranolol; Time Factors; Ventricular Fibrillation | 1987 |
Reassessment of AV and VA conduction and AV junctional reentry in the normal dog heart: the role of altered autonomic tone.
Topics: Animals; Atrioventricular Node; Atropine; Autonomic Agents; Cardiac Pacing, Artificial; Dogs; Electric Conductivity; Electrocardiography; Heart Conduction System; Isoproterenol; Metoprolol | 1988 |
On the mechanism of isoprenaline- and forskolin-induced depolarization of single guinea-pig ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Action Potentials; Albuterol; Animals; Colforsin; Cyclic AMP; Guinea Pigs; Heart; In Vitro Techniques; Ion Channels; Isoproterenol; Male; Metoprolol; Myocardium; Sodium; Temperature | 1988 |
Effects of selective and nonselective beta-adrenoceptor antagonism on isoproterenol-stimulated myocardial potassium uptake in the intact dog.
Topics: Animals; Dogs; Female; Hemodynamics; Hypokalemia; Isoproterenol; Male; Metoprolol; Myocardium; Potassium; Receptors, Adrenergic, beta | 1989 |
Antiarrhythmic effects of selective beta 1- and beta 2- and nonselective beta-adrenoceptor blockade in normokalaemic and dietary-induced hypokalaemic rats.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Catecholamines; Coronary Vessels; Diet; Heart Rate; Hypokalemia; Isoproterenol; Male; Metoprolol; Potassium; Propanolamines; Propranolol; Rats; Rats, Inbred Strains | 1989 |
Altered adrenergic response and specificity of the receptors in rat ascites hepatoma AH130.
Topics: Adenylyl Cyclases; Albuterol; Animals; Cell Line; Clonidine; Enzyme Activation; Epinephrine; Iodocyanopindolol; Isoproterenol; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Metoprolol; Norepinephrine; Pindolol; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1989 |
Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors.
Topics: Adolescent; Adult; Cardiomyopathy, Dilated; Child; Child, Preschool; Coronary Disease; Heart Failure; Humans; Infant; Isoproterenol; Metoprolol; Mitral Valve Stenosis; Myocardium; Propranolol; Receptors, Adrenergic, beta; Sotalol; Tetralogy of Fallot | 1989 |
Identification of functional beta-adrenergic receptors on AC glioma cells.
Topics: Animals; Cyclic AMP; Ethanolamines; Glioma; Isoproterenol; Metoprolol; Norepinephrine; Rats; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1989 |
The effects of beta-adrenoreceptor antagonists on the force responses of the electrically driven rat right ventricle strip to isoprenaline.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Electric Stimulation; Heart; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Myocardial Contraction; Pindolol; Propanolamines; Rats; Rats, Inbred Strains | 1989 |
Effects of selective and non-selective beta 1-blockade on renin secretion in the isolated rat kidney.
Topics: Adrenergic beta-Antagonists; Animals; Isoproterenol; Kidney; Male; Metoprolol; Practolol; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Renin; Secretory Rate; Species Specificity | 1989 |
Repeated swimming stress and responsiveness of the isolated rat pacemaker to the chronotropic effect of noradrenaline and isoprenaline: role of adrenal corticosteroids.
Topics: Adrenalectomy; Animals; Corticosterone; Heart Conduction System; Heart Rate; Isoproterenol; Male; Metoprolol; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stress, Physiological; Swimming | 1988 |
Comparison of the effects of adrenergic agonists and alpha-, beta 1-, beta 2-antagonists on the intraocular pressure and adenylate cyclase activity in the ciliary processes of the rabbit.
Topics: Acebutolol; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Ciliary Body; Intraocular Pressure; Isoproterenol; Labetalol; Metoprolol; Rats; Timolol; Water | 1985 |
Role of the autonomic nervous system in mediating the response to naloxone in canine hemorrhagic shock.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Nervous System; Blood Pressure; Dogs; Female; Heart Rate; Isoproterenol; Male; Mathematics; Metoprolol; Muscle Denervation; Naloxone; Phenoxybenzamine; Shock, Hemorrhagic; Stroke Volume | 1985 |
Beta-adrenergic control of motility in the rat colon. I. Evidence for functional separation of the beta 1- and beta 2-adrenoceptor-mediated inhibition of colon activity.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colon; Gastrointestinal Motility; Isoproterenol; Male; Metoprolol; Muscle, Smooth; Practolol; Prenalterol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sympathectomy; Terbutaline; Tetrodotoxin | 1986 |
Antihypertensive effects of 12 beta adrenoceptor antagonists in conscious spontaneously hypertensive rats: relationship to changes in plasma renin activity, heart rate and sympathetic nerve function.
Topics: Acebutolol; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Blood Pressure; Decerebrate State; Heart; Heart Rate; Hypertension; Isoproterenol; Levobunolol; Male; Metoprolol; Oxprenolol; Propranolol; Rats; Rats, Inbred SHR; Renin; Sympathetic Nervous System; Sympathomimetics; Time Factors | 1986 |
Specialization in beta-1 and beta-2 adrenoceptor distribution in veins of the rabbit face: relationship to myogenic tone and sympathetic nerve innervation.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Catechols; Electrophysiology; Face; Isoproterenol; Male; Metoprolol; Propanolamines; Propranolol; Rabbits; Receptors, Adrenergic, beta; Sympathetic Nervous System; Tetrodotoxin; Veins | 1987 |
Comparison of hemodynamic responses to isoproterenol infusion and surgical stress in patients given cardioselective and noncardioselective beta-adrenergic antagonists.
Topics: Adrenergic beta-Antagonists; Anesthesia, General; Atenolol; Coronary Artery Bypass; Dose-Response Relationship, Drug; Drug Evaluation; Heart; Heart Rate; Hemodynamics; Humans; Isoproterenol; Metoprolol; Propranolol; Receptors, Adrenergic, beta; Stimulation, Chemical; Stress, Physiological; Time Factors | 1987 |
Stereospecificity of beta adrenergic antagonists: R-enantiomers show increased selectivity for beta-2 receptors in ciliary process.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Betaxolol; Ciliary Body; Heart; Isoproterenol; Male; Metoprolol; Myocardium; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Stereoisomerism; Structure-Activity Relationship; Timolol | 1988 |
Simultaneous assessment of membrane-stabilizing and beta-adrenoceptor blocking activity of drugs with the rat isolated left atria.
Topics: Adrenergic beta-Antagonists; Animals; Atrial Function; Cell Membrane; Electric Stimulation; Heart Atria; Isoproterenol; Male; Metoprolol; Models, Biological; Myocardial Contraction; Procaine; Propranolol; Rats; Rats, Inbred Strains | 1988 |
Evidence for beta adrenoceptors in proximal tubules. Isoproterenol-sensitive adenylate cyclase in pars recta of canine nephron.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Dogs; Isoproterenol; Kidney Tubules, Proximal; Metoprolol; Nephrons; Norepinephrine; Propanolamines; Propranolol; Receptors, Adrenergic, beta | 1985 |
Characterization of functional beta-adrenoceptor subtypes in rabbit urinary bladder smooth muscle.
Topics: Animals; Butoxamine; Dobutamine; Isoproterenol; Male; Metoprolol; Muscle Contraction; Muscle, Smooth; Propranolol; Rabbits; Receptors, Adrenergic, beta; Terbutaline; Urinary Bladder | 1986 |
Evidence of beta-adrenergic involvement in forced swimming-induced behavioural despair of mice.
Topics: Animals; Atenolol; Behavior, Animal; Female; Imipramine; Immobilization; Isoproterenol; Male; Metoprolol; Mice; Physical Exertion; Propranolol; Receptors, Adrenergic, beta; Reserpine; Stress, Psychological; Swimming | 1987 |
[Cardiogenic shock caused by metoprolol poisoning. Reversibility with high doses of glucagon and isoproterenol].
Topics: Adult; Drug Therapy, Combination; Female; Glucagon; Humans; Isoproterenol; Metoprolol; Shock, Cardiogenic | 1985 |
The effect of epidermal growth factor on chronotropic response in cardiac cells in culture.
Topics: Animals; Cells, Cultured; Chick Embryo; Epidermal Growth Factor; Heart Rate; Heart Ventricles; Isoproterenol; Metoprolol | 1987 |
Autonomic control of ventricular tachycardia: direct effects of beta-adrenergic blockade in 24 hour old canine myocardial infarction.
Topics: Animals; Coronary Vessels; Dogs; Female; Heart Conduction System; Hemodynamics; Injections, Intra-Arterial; Isoproterenol; Male; Metoprolol; Myocardial Infarction; Phenylephrine; Tachycardia | 1987 |
Catecholamine secretion from the rabbit adrenal gland is not modulated by a mechanism involving beta-adrenoceptors.
Topics: Adrenal Glands; Animals; Catecholamines; Electric Stimulation; Epinephrine; Feedback; In Vitro Techniques; Isoproterenol; Metoprolol; Propranolol; Rabbits; Receptors, Adrenergic, beta; Splanchnic Nerves | 1984 |
Pharmacological evidence for differences in the beta-adrenoreceptor populations mediating atrial and ventricular chronotropic responses in the unanaesthetized dog.
Topics: Alprenolol; Anesthesia; Animals; Dogs; Electrocardiography; Female; Heart Rate; Isoproterenol; Male; Metoprolol; Parasympatholytics; Propranolol; Receptors, Adrenergic, beta | 1984 |
Adrenergic drugs and intraocular pressure: suppression of ocular hypertension induced by water loading.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Dobutamine; Ephedrine; Epinephrine; Intraocular Pressure; Isoproterenol; Male; Metoprolol; Propranolol; Pupil; Rabbits; Sympathomimetics; Terbutaline; Timolol; Water | 1980 |
Metoprolol in essential tremor.
Topics: Dose-Response Relationship, Drug; Humans; Isoproterenol; Metoprolol; Propanolamines; Propranolol; Tremor | 1980 |
Pre- and postjunctional beta-adrenoceptor mediated effects on transmitter release and effector response in the isolated rat portal vein.
Topics: Animals; Autacoids; Electric Stimulation; Female; Hypertension; Isoproterenol; Male; Metoprolol; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Portal Vein; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetrodotoxin; Vasoconstriction | 1980 |
[Cholinergic antagonism by beta-blockers. I. Spectrum of interactions].
Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart; Ileum; Isoproterenol; Labetalol; Male; Metoprolol; Pindolol; Practolol; Propranolol; Receptors, Cholinergic; Sotalol | 1980 |
[Cholinergic antagonism by beta-blockers. II. Sequence of interactions and final steady state effects].
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Drug Interactions; Guinea Pigs; Heart; Isoproterenol; Labetalol; Male; Metoprolol; Practolol; Propranolol; Receptors, Cholinergic; Time Factors | 1980 |
Effects of selective and non-selective beta-adrenergic agents on insulin secretion in vivo.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Butoxamine; Carbachol; Dose-Response Relationship, Drug; Female; Glucose; Insulin; Insulin Secretion; Isoproterenol; Metoprolol; Mice; Propanolamines; Propranolol; Terbutaline; Thiazoles | 1981 |
Adrenergic beta receptors mediating submandibular salivary gland hypertrophy in the rat.
Topics: Adrenergic beta-Agonists; Animals; Cardiomegaly; Dose-Response Relationship, Drug; Hypertrophy; Isoproterenol; Male; Metoprolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Submandibular Gland | 1981 |
Beta-adrenergic drugs do not affect phrenic nerve afterdischarge.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cats; In Vitro Techniques; Isoproterenol; Metoprolol; Phrenic Nerve; Time Factors | 1981 |
Abrupt withdrawal of chronic beta-blockade: adaptive changes in cyclic AMP and contractility.
Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Animals; Cyclic AMP; Heart; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Myocardial Contraction; Myocardium; Oxprenolol; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1981 |
Characterization of the beta-adrenergic inhibition of motility in cat colon strips.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cats; Colon; Female; Gastrointestinal Motility; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Practolol; Prenalterol; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, beta; Terbutaline; Tetrodotoxin | 1982 |
Studies on beta-adrenoceptor mediated facilitation of sympathetic neurotransmission.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Epinephrine; Hindlimb; Isoproterenol; Metoprolol; Norepinephrine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Stereoisomerism; Sympathetic Nervous System; Synaptic Transmission; Vasoconstriction | 1981 |
Relevance of selectivity and non-selectivity in beta-adrenoceptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Adult; Atropine; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Norepinephrine; Organ Specificity; Propranolol | 1982 |
Effects of beta-adrenoceptor agonists and antagonists in patients with peripheral autonomic neuropathy.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Albuterol; Amyloidosis; Autonomic Nervous System Diseases; Blood Pressure; Female; Heart Rate; Humans; Hypotension, Orthostatic; Isoproterenol; Male; Metoprolol; Middle Aged; Peripheral Nervous System Diseases; Pindolol; Posture; Propranolol | 1982 |
Basic pharmacological properties of prenalterol.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Cats; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Metoprolol; Myocardial Contraction; Papillary Muscles; Phentolamine; Practolol; Prenalterol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Terbutaline; Vascular Resistance | 1982 |
Studies of catecholamine effect on cyclic AMP in human cultured thyroid cells: their interaction with thyrotrophin receptor.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cells, Cultured; Cyclic AMP; DNA; Epinephrine; Humans; Isoproterenol; Metoprolol; Norepinephrine; Practolol; Prenalterol; Receptors, Cell Surface; Receptors, Thyrotropin; Terbutaline; Thyroid Gland; Thyrotropin | 1983 |
Subclassification of human beta-adrenergic receptors mediating renin release.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Betaxolol; Dobutamine; Fenoterol; Humans; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Renin | 1983 |
The effect of alpha- and beta-adrenoceptor antagonist agents on reperfusion ventricular fibrillation and metabolic status in the isolated perfused rat heart.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arterial Occlusive Diseases; Atenolol; Coronary Circulation; Coronary Disease; Isoproterenol; Metoprolol; Perfusion; Phentolamine; Prazosin; Propranolol; Rats; Time Factors; Ventricular Fibrillation; Yohimbine | 1983 |
The influence of vascular beta-adrenoceptors on the position and mobility of the rabbit incisor tooth.
Topics: Adrenergic beta-Antagonists; Animals; Electric Stimulation; Ephedrine; Female; Incisor; Isoproterenol; Male; Metoprolol; Periodontal Ligament; Propanolamines; Propranolol; Rabbits; Sympathetic Nervous System; Tooth Mobility; Vascular Resistance; Vasoconstriction | 1982 |
Beta-blockers in isoproterenol-enhanced essential tremor.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Humans; Isoproterenol; Metoprolol; Middle Aged; Propranolol; Timolol; Tremor | 1984 |
Adrenergic effects on plasma levels of glucagon, insulin, glucose and free fatty acids in rabbits--influences of selective blocking drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Insulin; Isoproterenol; Metoprolol; Prazosin; Propanolamines; Rabbits; Yohimbine | 1984 |
Beta 2-adrenergic stimulation of androgen production by cultured mouse testicular interstitial cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Androgens; Animals; Cells, Cultured; Isoproterenol; Kinetics; Leydig Cells; Luteinizing Hormone; Male; Metoprolol; Mice; Propanolamines; Propranolol | 1984 |
Influence of long-term beta receptor stimulation with prenalterol on intrinsic heart rate in rats.
Topics: Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Exercise Test; Female; Heart Rate; Isoproterenol; Metoprolol; Physical Exertion; Practolol; Prenalterol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stimulation, Chemical | 1984 |
Impaired beta-adrenergic stimulation in the uninvolved ventricle post-acute myocardial infarction: reversible defect due to excessive circulating catecholamine-induced decline in number and affinity of beta-receptors.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Coronary Circulation; Female; Guinea Pigs; Isoproterenol; Metoprolol; Myocardial Contraction; Myocardial Infarction; Myocardium; Phosphoric Diester Hydrolases; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reserpine | 1981 |
Cardiac contractile and metabolic effects mediated via the myocardial H2-receptor adenylate cyclase system. Characterization of two new specific H2-receptor agonists, impromidine and dimaprit, in the guinea pig and human myocardium.
Topics: Adenylyl Cyclases; Animals; Cimetidine; Cyclic AMP; Dimaprit; Dose-Response Relationship, Drug; Female; Guanidines; Guinea Pigs; Histamine; Humans; Imidazoles; Impromidine; Isoproterenol; Metoprolol; Myocardial Contraction; Myocardial Infarction; Myocardium; Phosphoric Diester Hydrolases; Receptors, Histamine; Receptors, Histamine H2; Thiourea; Tyramine | 1981 |
Modulation by beta-adrenoreceptors of spontaneous contractions of rat urinary bladder.
Topics: Animals; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Muscle Contraction; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Terbutaline; Urinary Bladder | 1982 |
The identification and characterization of beta-adrenergic receptors in human amnion tissue.
Topics: Amnion; Binding, Competitive; Cyclic AMP; Ethanolamines; Female; Humans; Iodocyanopindolol; Isoproterenol; Metoprolol; Pindolol; Pregnancy; Propranolol; Receptors, Adrenergic, beta | 1984 |
Beta 1 - beta 2 blocking activity of propranolol and metoprolol in the unanaesthetized genetically hypertensive and normotensive rat.
Topics: Animals; Blood Pressure; Heart Rate; Hypertension; Isoproterenol; Male; Metoprolol; Pressoreceptors; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1984 |
Effect of epinephrine on renal potassium excretion in the isolated perfused rat kidney.
Topics: Animals; Butoxamine; Epinephrine; Glomerular Filtration Rate; Isoproterenol; Kidney; Male; Metoprolol; Natriuresis; Perfusion; Potassium; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Urination | 1984 |
Reduction of catecholamine-induced cardiovascular malformations in the chick embryo with metoprolol.
Topics: Abnormalities, Drug-Induced; Animals; Aorta, Thoracic; Cardiovascular Abnormalities; Catecholamines; Chick Embryo; Dopamine; Drug Antagonism; Epinephrine; Isoproterenol; Metoprolol; Norepinephrine; Teratogens | 1983 |
Predictability of antihypertensive efficacy of selective beta 1 blockers.
Topics: Adult; Aldosterone; Atenolol; Blood Pressure; Cardiac Output; Catecholamines; Echocardiography; Female; Heart Rate; Humans; Hypertension; Isoproterenol; Male; Metoprolol | 1983 |
Effect of adrenergic stimulation and blockade on ventricular defibrillation in the rat.
Topics: Albuterol; Animals; Atropine; Isoproterenol; Male; Metoprolol; Norepinephrine; Phenoxybenzamine; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Sympathomimetics; Time Factors; Ventricular Fibrillation | 1983 |
The effect of cimetidine on the relative cardioselectivity of atenolol and metoprolol in asthmatic patients.
Topics: Asthma; Atenolol; Cimetidine; Double-Blind Method; Drug Interactions; Forced Expiratory Volume; Heart; Heart Rate; Humans; Isoproterenol; Metoprolol; Organ Specificity | 1984 |
Attenuation of arterial baroreflex control of heart rate by left ventricular receptor stimulation in the conscious dog.
Topics: Acetylcholine; Animals; Atropine Derivatives; Blood Pressure; Carotid Sinus; Denervation; Dogs; Efferent Pathways; Female; Heart; Heart Rate; Heart Ventricles; Isoproterenol; Male; Metoprolol; Pressoreceptors; Stimulation, Chemical; Veratrine | 1983 |
Metoprolol withdrawal phenomena: mechanism and prevention.
Topics: Adult; Aged; Blood Pressure; Drug Administration Schedule; Epinephrine; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Norepinephrine; Propanolamines; Substance Withdrawal Syndrome; Thyroxine; Triiodothyronine | 1982 |
Cardiac hyper- and hyporesponsiveness after pindolol withdrawal.
Topics: Adult; Blood Pressure; Catecholamines; Female; Heart; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Pindolol; Substance Withdrawal Syndrome; Thyroid Hormones; Time Factors | 1982 |
Endothelial prostacyclin production, synergistic effect between adrenergic stimulating and blocking drugs.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Adrenergic Agonists; Adrenergic Antagonists; Cells, Cultured; Drug Synergism; Endothelium, Vascular; Epoprostenol; Humans; Isoproterenol; Metoprolol; Propranolol; Umbilical Veins | 1994 |
Plasma catecholamines and cyclic AMP response during head-up tilt test in patients with neurocardiogenic (vasodepressor) syncope.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Catecholamines; Cyclic AMP; Female; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Norepinephrine; Posture; Propranolol; Syncope; Vasoconstriction | 1995 |
Effect of losartan, an AT1 selective angiotensin II receptor antagonist, on isoproterenol-induced cardiac ornithine decarboxylase activity.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Heart; Imidazoles; In Vitro Techniques; Isoproterenol; Losartan; Metoprolol; Myocardium; Nephrectomy; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Rats, Wistar; Tetrazoles | 1995 |
[The correction of the hemodynamic disorders in patients with IHD complicated by intraventricular blocks by using beta-adrenergic agents].
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Bundle-Branch Block; Drug Evaluation; Female; Hemodynamics; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Propranolol; Time Factors | 1995 |
Demonstration of an in vivo functional beta 3-adrenoceptor in man.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Adult; Analysis of Variance; Animals; Body Temperature Regulation; Cells, Cultured; Dobutamine; Female; Humans; Isoproterenol; Kinetics; Lipolysis; Male; Mammals; Metoprolol; Microdialysis; Middle Aged; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Reference Values; Regional Blood Flow; Terbutaline; Time Factors | 1995 |
Interactive and discontinuous long-lasting potentiation in the dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Male; Metoprolol; Propranolol; Rats; Rats, Wistar; Sincalide | 1994 |
Acute effects of catecholamines on function of the rat right heart.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Carvedilol; Catecholamines; Female; Heart Rate; Isoproterenol; Metoprolol; Norepinephrine; Prazosin; Propanolamines; Rats; Rats, Sprague-Dawley; Ventricular Function, Right | 1993 |
Intact cell binding properties of cells expressing altered beta-adrenergic receptors.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; beta-Adrenergic Receptor Kinases; Binding, Competitive; Cell Line; Cricetinae; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Isoproterenol; L Cells; Metoprolol; Mice; Mutation; Phosphorylation; Pindolol; Receptors, Adrenergic, beta; Transfection | 1994 |
Induction of long-lasting potentiation by sequenced applications of isoproterenol.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adrenergic beta-Antagonists; Animals; Drug Administration Schedule; Drug Synergism; Electric Stimulation; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Metoprolol; Neuronal Plasticity; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, N-Methyl-D-Aspartate | 1994 |
Pathway specificity of noradrenergic plasticity in the dentate gyrus.
Topics: Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Neuronal Plasticity; Norepinephrine; Rats; Synaptic Transmission; Time Factors | 1994 |
Tilt-table testing and oral metoprolol therapy in young patients with unexplained syncope.
Topics: Administration, Oral; Adolescent; Blood Pressure; Child; Female; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Posture; Syncope | 1994 |
Effects of metoprolol on left ventricular function in rats with myocardial infarction.
Topics: Animals; Blood Pressure; Coronary Vessels; Diastole; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Myocardial Infarction; Papillary Muscles; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Reference Values; Systole; Ventricular Function, Left | 1994 |
Effects of antimycin A on the binding properties of beta and alpha-1 adrenergic receptors measured on intact cells.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Cells, Cultured; Cricetinae; Epinephrine; In Vitro Techniques; Isoproterenol; Metoprolol; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1993 |
Effects of escapable and inescapable foot-shock on rat atrial beta-adrenoceptors.
Topics: Animals; Butoxamine; Electroshock; Ethanolamines; Heart Atria; Heart Rate; Isoproterenol; Male; Metoprolol; Myocardium; Norepinephrine; Oxidopamine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Stress, Psychological; Sympathectomy, Chemical | 1993 |
[Malignant vasovagal syncope: its diagnosis and therapeutic trial based on the orthostatism test (the tilt-table test)].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Chronic Disease; Clonidine; Female; Heart Function Tests; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Posture; Recurrence; Scopolamine; Syncope | 1993 |
Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor.
Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Alprenolol; Animals; Asparagine; Binding Sites; CHO Cells; Computer Simulation; Cricetinae; Humans; Isoproterenol; Metoprolol; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Propranolol; Receptors, Adrenergic, beta-2; Serine; Signal Transduction; Stereoisomerism | 1996 |
Response to beta blockers in patients with neurocardiogenic syncope: how to predict beneficial effects.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Electrocardiography; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Isoproterenol; Male; Metoprolol; Middle Aged; Posture; Propanolamines; Recurrence; Syncope, Vasovagal; Treatment Outcome | 1996 |
Malignant vasovagal syncope: a randomised trial of metoprolol and clonidine.
Topics: Adrenergic beta-Agonists; Antihypertensive Agents; Clonidine; Humans; Isoproterenol; Metoprolol; Syncope, Vasovagal; Tilt-Table Test | 1998 |
Interaction between substance P and beta-adrenergic agonists in the modulation of the secretion of fluid and protein by the rat submandibular gland.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dobutamine; Drug Interactions; Injections, Intravenous; Isoproterenol; Male; Metoprolol; Propanolamines; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Saliva; Submandibular Gland; Substance P; Terbutaline | 1998 |
Effect of metoprolol administration on renal sodium handling in experimental congestive heart failure.
Topics: Adrenergic beta-Agonists; Animals; Diet, Sodium-Restricted; Heart Failure; Hemodynamics; Isoproterenol; Kidney; Male; Metoprolol; Natriuresis; Rats; Rats, Sprague-Dawley; Sodium, Dietary; Ventricular Function, Left | 1999 |
Impaired isoproterenol-induced hyperpolarization in isolated mesenteric arteries of aged rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Age Factors; Aging; Animals; Butoxamine; Colforsin; Cromakalim; Data Interpretation, Statistical; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Mesenteric Arteries; Metoprolol; Muscle, Smooth, Vascular; Potassium Channels; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Vasodilator Agents | 1999 |
Stress-induced alteration in the lipolytic response to beta-adrenoceptor agonists in rat white adipocytes.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Body Weight; Bucladesine; Eating; Epinephrine; Ethanolamines; Glycerol; Isoproterenol; Lipolysis; Male; Metoprolol; Norepinephrine; Propanolamines; Rats; Rats, Wistar; Stress, Physiological | 1999 |
beta-adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling.
Topics: Adrenergic beta-Antagonists; Animals; Cytokines; Gene Expression; Interleukin-1; Interleukin-6; Isoproterenol; Metoprolol; Myocardial Infarction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left; Ventricular Remodeling | 2000 |
Safety and tolerability of an aggressive tilt table test protocol in the evaluation of patients with suspected neurocardiogenic syncope.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Hypersensitivity; Electrocardiography; Female; Hemodynamics; Humans; Infusions, Intravenous; Isoproterenol; Male; Metoprolol; Middle Aged; Prognosis; Safety; Sympatholytics; Sympathomimetics; Syncope, Vasovagal; Tilt-Table Test | 2000 |
Characterization of beta-adrenoceptors responsible for venom production in the venom gland of the snake Bothrops jararaca.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Bothrops; Crotalid Venoms; Cyclic AMP; Dioxoles; Ethanolamines; Exocrine Glands; Female; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Kinetics; Male; Membranes; Metoprolol; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2000 |
Establishment and characterization of steroidogenic granulosa cells expressing beta(2)-adrenergic receptor: regulation of adrenodoxin and steroidogenic acute regulatory protein by adrenergic agents.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenodoxin; Animals; Blotting, Western; Cell Line, Transformed; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Female; Follicle Stimulating Hormone; Genes, ras; Granulosa Cells; Immunohistochemistry; Isoproterenol; Metoprolol; Phosphodiesterase Inhibitors; Phosphoproteins; Plasmids; Progesterone; Propranolol; Rats; Receptors, Adrenergic, beta-2; Simian virus 40; Transfection | 2000 |
Differential effects of carvedilol and metoprolol on isoprenaline-induced changes in beta-adrenoceptor density and systolic function in rat cardiac myocytes.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Carbazoles; Carvedilol; Cell Size; Cells, Cultured; Electric Stimulation; Guanylyl Imidodiphosphate; Isoproterenol; Male; Metoprolol; Microscopy, Phase-Contrast; Myocardium; Propanolamines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Regression Analysis | 2001 |
beta(1)-Adrenoceptor antibodies induce positive inotropic response in isolated cardiomyocytes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antibodies, Monoclonal; Cell Size; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Heart; Humans; Isoproterenol; Metoprolol; Mice; Mice, Inbred BALB C; Myocardial Contraction; Myocardium; Propanolamines; Rats; Receptors, Adrenergic, beta-1; Thionucleotides | 2001 |
Nebivolol, bucindolol, metoprolol and carvedilol are devoid of intrinsic sympathomimetic activity in human myocardium.
Topics: Adrenergic beta-Antagonists; Benzopyrans; Binding, Competitive; Bisoprolol; Carbazoles; Carvedilol; Ethanolamines; Female; Guanylyl Imidodiphosphate; Heart Ventricles; Humans; Imidazoles; In Vitro Techniques; Inhibitory Concentration 50; Isoproterenol; Male; Metoprolol; Middle Aged; Myocardial Contraction; Myocardium; Nebivolol; Propanolamines; Substrate Specificity; Sympathetic Nervous System; Sympathomimetics; Thermodynamics | 2001 |
Emotional stress activates MAP kinase in the rat heart.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Ethanolamines; Heart; Immobilization; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; Perfusion; Phenylephrine; Prazosin; Rats; Rats, Wistar; Stress, Psychological | 2001 |
Catecholamine stimulation is associated with impaired myocardial O(2) utilization in heart failure.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Cardiomyopathy, Dilated; Catecholamines; Dobutamine; Dogs; Female; Isoproterenol; Male; Metoprolol; Models, Animal; Myocardial Contraction; Myocardium; Norepinephrine; Oxygen Consumption; Phenylephrine; Stimulation, Chemical | 2002 |
Pharmacological blockade of the dive response: effects on heart rate and diving behaviour in the harbour seal (Phoca vitulina).
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Diamines; Diving; Heart Rate; Isoproterenol; Metoprolol; Muscarinic Antagonists; Phenylephrine; Prazosin; Seals, Earless; Vasoconstriction | 2002 |
Beta1-adrenoceptor antibodies induce apoptosis in adult isolated cardiomyocytes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antibodies, Monoclonal; Apoptosis; Cyclic AMP-Dependent Protein Kinases; Enzyme-Linked Immunosorbent Assay; In Situ Nick-End Labeling; In Vitro Techniques; Isoproterenol; Metoprolol; Mice; Myocytes, Cardiac; Peptide Fragments; Rats; Receptors, Adrenergic, beta-1 | 2003 |
Interaction between noradrenaline or adrenaline and the beta 1-adrenergic receptor in the nervous system triggers early metamorphosis of larvae in the ascidian, Ciona savignyi.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Butoxamine; Dose-Response Relationship, Drug; Epinephrine; Immunohistochemistry; Isoproterenol; Larva; Metamorphosis, Biological; Metoprolol; Nervous System; Norepinephrine; Phentolamine; Propranolol; Receptors, Adrenergic, beta; Urochordata | 2003 |
Lack of inverse agonistic activity of nebivolol, its D- and L-enantiomers and of in vivo metabolized nebivolol in human myocardium.
Topics: Adenylyl Cyclases; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Aged; Benzopyrans; Colforsin; Ethanolamines; Humans; In Vitro Techniques; Isometric Contraction; Isoproterenol; Metoprolol; Myocardial Contraction; Myocardium; Nebivolol; Radioligand Assay; Stereoisomerism; Stimulation, Chemical; Structure-Activity Relationship | 2003 |
Anterior hypothalamic beta-adrenergic activity in the maintenance of hypertension in aortic coarctated rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anterior Hypothalamic Nucleus; Aortic Coarctation; Atenolol; Blood Pressure; Clenbuterol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Hypertension; Hypotension; Isoproterenol; Male; Metoprolol; Microinjections; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 2004 |
NFATc3-induced reductions in voltage-gated K+ currents after myocardial infarction.
Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclosporine; DNA-Binding Proteins; Electric Conductivity; Isoproterenol; Kinetics; Metoprolol; Mice; Mice, Knockout; Myocardial Infarction; Myocytes, Cardiac; NFATC Transcription Factors; Potassium Channels, Voltage-Gated; Transcription Factors | 2004 |
Heme oxygenase-1 gene expression in pericentral hepatocytes through beta1-adrenoceptor stimulation.
Topics: Adrenergic Agonists; Animals; Arteries; Cyclic AMP-Dependent Protein Kinases; Dobutamine; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Heart Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatocytes; Isoproterenol; Liver; Male; Metoprolol; Rats; Receptors, Adrenergic, beta | 2004 |
Enantioseparation using sulfated cyclosophoraoses as a novel chiral additive in capillary electrophoresis.
Topics: Atenolol; Electrolytes; Electrophoresis, Capillary; Isoproterenol; Metoprolol; Molecular Structure; Norepinephrine; Oligosaccharides; Propranolol; Rhizobium leguminosarum; Stereoisomerism | 2004 |
Central beta-adrenoceptors mediate phasic and sustained components of hemodynamic responses to acute behavioral stress.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Blood Pressure; Cardiac Output; Central Nervous System; Cold Temperature; Drug Interactions; Heart Rate; Hemodynamics; Isoproterenol; Male; Metoprolol; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Reflex, Startle; Stress, Physiological; Time Factors; Vascular Resistance; Wakefulness | 2005 |
Spontaneous diastolic contractions and phosphorylation of the cardiac ryanodine receptor at serine-2808 in congestive heart failure in rat.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Diastole; Echocardiography; Heart Failure; Isoproterenol; Male; Metoprolol; Models, Animal; Myocardial Contraction; Phosphorylation; Rats; Rats, Inbred BN; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Serine; Tacrolimus | 2006 |
The effects of combined versus selective adrenergic blockade on left ventricular and systemic hemodynamics, myocardial substrate preference, and regional perfusion in conscious dogs with dilated cardiomyopathy.
Topics: Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Dogs; Heart Rate; Hemodynamics; Isoproterenol; Metoprolol; Myocardium; Propanolamines; Regional Blood Flow; Ventricular Function, Left | 2006 |
Enhanced isoproterenol-induced cardiac hypertrophy in transgenic rats with low brain angiotensinogen.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensinogen; Animals; Animals, Genetically Modified; Brain; Cardiomegaly; Consciousness; Heart Rate; Hypertrophy, Left Ventricular; Isoproterenol; Male; Metoprolol; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Left | 2006 |
Effect of age on vascular beta2-adrenergic receptor desensitization is not mediated by the receptor coupling to Galphai proteins.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Aorta; GTP-Binding Protein alpha Subunits, Gi-Go; Isoproterenol; Male; Metoprolol; Pertussis Toxin; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Vasodilation | 2006 |
Functional analysis of endogenous beta-adrenergic receptor through fluorimetric monitoring of cyclic nucleotide-gated ion channel.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cell Line; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Dose-Response Relationship, Drug; Fluorometry; Humans; Ion Channels; Isoproterenol; Metoprolol; Receptors, Adrenergic, beta | 2007 |
Effect of beta-adrenoceptors on the behaviour induced by the neuropeptide glutamic acid isoleucine amide.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Dobutamine; Grooming; Isoproterenol; Male; Metoprolol; Motor Activity; Oligopeptides; Phentolamine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1 | 2007 |
Exercise training and beta-blocker treatment ameliorate age-dependent impairment of beta-adrenergic receptor signaling and enhance cardiac responsiveness to adrenergic stimulation.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Blood Pressure; Heart; Heart Rate; Isoproterenol; Male; Metoprolol; Myocardial Contraction; Physical Conditioning, Animal; Random Allocation; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Signal Transduction; Ventricular Function, Left | 2007 |
Aristolochic Acid induces heart failure in zebrafish embryos that is mediated by inflammation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aristolochic Acids; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Embryo, Nonmammalian; Endocardium; Gene Expression; Gene Expression Regulation, Developmental; Heart; Heart Failure; Inflammation; Isoproterenol; Metoprolol; Mutagens; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Nitrobenzenes; Sulfonamides; Zebrafish | 2007 |
Simultaneous separation of eight beta-adrenergic drugs using titanium dioxide nanoparticles as additive in capillary electrophoresis.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Atenolol; Buffers; Celiprolol; Clenbuterol; Electroosmosis; Electrophoresis, Capillary; Fenoterol; Hydrogen-Ion Concentration; Isoproterenol; Metal Nanoparticles; Metoprolol; Propranolol; Reproducibility of Results; Terbutaline; Titanium; Uncertainty | 2008 |
Comparison of pharmacodynamics between carvedilol and metoprolol in rats with isoproterenol-induced cardiac hypertrophy: effects of carvedilol enantiomers.
Topics: Adenylyl Cyclases; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Cardiomegaly; Carvedilol; Cyclic AMP; Disease Models, Animal; Heart Failure; Heart Rate; Isoproterenol; Male; Metoprolol; Myocardium; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Time Factors; Ventricular Function, Left | 2008 |
Dissociation between cardiomyocyte function and remodeling with beta-adrenergic receptor blockade in isolated canine mitral regurgitation.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cell Shape; Collagen; Disease Models, Animal; Dogs; Female; Imaging, Three-Dimensional; Isoproterenol; Magnetic Resonance Imaging; Male; Metoprolol; Mitral Valve Insufficiency; Myocardial Contraction; Myocytes, Cardiac; Receptors, Adrenergic, beta-1; Stroke Volume; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2008 |
Influence of plasma protein binding on pharmacodynamics: Estimation of in vivo receptor affinities of beta blockers using a new mechanism-based PK-PD modelling approach.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Blood Proteins; Dose-Response Relationship, Drug; Heart Rate; Isoproterenol; Male; Metoprolol; Models, Biological; Propranolol; Protein Binding; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Timolol | 2009 |
Nuclear targeting of FBPase in HL-1 cells is controlled by beta-1 adrenergic receptor-activated Gs protein signaling cascade.
Topics: Active Transport, Cell Nucleus; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cell Line; Cell Nucleus; Colforsin; Culture Media; Cyclic AMP-Dependent Protein Kinases; Fructose-Bisphosphatase; GTP-Binding Protein alpha Subunits, Gs; Isoproterenol; Metoprolol; Mice; Myocytes, Cardiac; Norepinephrine; Receptors, Adrenergic, beta-1; Second Messenger Systems | 2009 |
Characterization of mouse heart adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Catalysis; Cations, Divalent; Cell Line; Cell Membrane; Colforsin; Enzyme Inhibitors; Female; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoenzymes; Isoproterenol; Kinetics; Metoprolol; Mice; Mice, Inbred Strains; Myocardium; Protein Isoforms; Receptors, G-Protein-Coupled; Recombinant Proteins; Spodoptera | 2009 |
Both beta1- and beta2-adrenoceptors contribute to feedforward coronary resistance vessel dilation during exercise.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Coronary Vessels; Female; Isoproterenol; Male; Metoprolol; Models, Animal; Myocardium; Norepinephrine; Oxygen; Physical Conditioning, Animal; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Regional Blood Flow; Swine; Vascular Resistance; Vasodilation | 2010 |
Cardiac gap junction channels are upregulated by metoprolol: an unexpected effect of beta-blockers.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blotting, Western; Connexin 43; Gap Junctions; Heart Rate; Ion Channels; Isoproterenol; Metoprolol; Mitogen-Activated Protein Kinase 1; Myocardial Contraction; Myocytes, Cardiac; Phosphorylation; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2010 |
Effects of β-adrenoceptor stimulation on delayed rectifier K(+) currents in canine ventricular cardiomyocytes.
Topics: Action Potentials; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Delayed Rectifier Potassium Channels; Dogs; Heart Ventricles; Imidazoles; Isoproterenol; Kinetics; Metoprolol; Myocytes, Cardiac; Patch-Clamp Techniques; Protein Kinase Inhibitors; Receptors, Adrenergic, beta-1; Signal Transduction; Single-Cell Analysis | 2011 |
β2 adrenergic-mediated reduction of blood glutamate levels and improved neurological outcome after traumatic brain injury in rats.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Animals; Behavior, Animal; Blood Glucose; Blood Pressure; Brain Injuries; Butoxamine; Glutamic Acid; Head Injuries, Closed; Heart Rate; Hemodynamics; Isoproterenol; Male; Metoprolol; Movement; Nervous System Diseases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Treatment Outcome | 2012 |
Transforming growth factor β₁ oppositely regulates the hypertrophic and contractile response to β-adrenergic stimulation in the heart.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cardiomegaly; Cells, Cultured; Echocardiography, Stress; Gene Expression Regulation; Heart; Humans; Ion Channels; Isoproterenol; Metoprolol; Mice; Mice, Transgenic; Mitochondrial Proteins; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan; Transforming Growth Factor beta1; Uncoupling Protein 3 | 2011 |
The effect of c-fos on acute myocardial infarction and the significance of metoprolol intervention in a rat model.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Female; Gene Expression; Immunohistochemistry; In Situ Hybridization; Isoproterenol; Metoprolol; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Organ Size; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; RNA, Messenger | 2013 |
β1-Adrenoceptor autoantibodies from DCM patients enhance the proliferation of T lymphocytes through the β1-AR/cAMP/PKA and p38 MAPK pathways.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Aged; Animals; Autoantibodies; Cardiomyopathy, Dilated; Cell Proliferation; Cyclic AMP-Dependent Protein Kinases; Female; Humans; Imidazoles; Interferon-gamma; Isoproterenol; Isoquinolines; Male; Metoprolol; Middle Aged; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Signal Transduction; Sulfonamides; T-Lymphocytes | 2012 |
Nebivolol prevents desensitization of β-adrenoceptor signaling and induction of cardiac hypertrophy in response to isoprenaline beyond β1-adrenoceptor blockage.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Benzopyrans; Calcium-Binding Proteins; Cardiomegaly; Coronary Circulation; Ethanolamines; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Nebivolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Transcription, Genetic | 2013 |
β-Adrenergic receptor agonist increases voltage-gated Na(+) currents in medial prefrontal cortex pyramidal neurons.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclic AMP-Dependent Protein Kinases; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Metoprolol; Prefrontal Cortex; Propranolol; Protein Kinase C; Pyramidal Cells; Rats; Receptors, Adrenergic, beta-1; Voltage-Gated Sodium Channels | 2015 |
Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclic AMP-Dependent Protein Kinases; Glucose Transporter Type 4; HEK293 Cells; Humans; Insulin Resistance; Isoproterenol; Metoprolol; Mice; Myocardium; Myocytes, Cardiac; Propranolol; Rats; Receptors, Adrenergic, beta; Signal Transduction | 2016 |
Atomic force microscopy combined with human pluripotent stem cell derived cardiomyocytes for biomechanical sensing.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Biomechanical Phenomena; Biosensing Techniques; Cell Culture Techniques; Cell Line; Drug Evaluation, Preclinical; Equipment Design; Humans; Isoproterenol; Metoprolol; Microscopy, Atomic Force; Myocardial Contraction; Myocytes, Cardiac; Pluripotent Stem Cells | 2016 |
Somatic and dendritic perforated-patch recordings reveal b-adrenergic receptor-induced depolarization in medial prefrontal cortex pyramidal neurons.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Biophysics; Bronchodilator Agents; Colforsin; Dendrites; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Metoprolol; Patch-Clamp Techniques; Prefrontal Cortex; Protein Kinase Inhibitors; Pyramidal Cells; Rats; Receptors, Adrenergic, beta; Sodium Channel Blockers; Tetrodotoxin | 2016 |
Exercise training bradycardia is largely explained by reduced intrinsic heart rate.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Adult; Age Factors; Aged; Autonomic Nervous System; Bradycardia; Exercise; Female; Healthy Volunteers; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Receptors, Adrenergic, beta | 2016 |
Genetic background dominates the susceptibility to ventricular arrhythmias in a murine model of β-adrenergic stimulation.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Genetic Background; Genetic Predisposition to Disease; Isoproterenol; Metoprolol; Mice, Inbred BALB C; Mice, Inbred C57BL | 2018 |
Effect of ethanolic extract of Cyperus rotundus L. against isoprenaline induced cardiotoxicity.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Cardiotoxicity; Cardiovascular Agents; Cyperus; Cytoprotection; Disease Models, Animal; Ethanol; Isoproterenol; Male; Metoprolol; Myocardial Infarction; Myocardium; Necrosis; Phytotherapy; Plant Extracts; Plants, Medicinal; Ramipril; Rats, Wistar; Rhizome; Solvents | 2016 |
The cardioprotective effects of icariin on the isoprenaline-induced takotsubo-like rat model: Involvement of reactive oxygen species and the TLR4/NF-κB signaling pathway.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Echocardiography; Fibrosis; Flavonoids; Humans; Isoproterenol; Male; Metoprolol; Myocardium; NF-kappa B; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Takotsubo Cardiomyopathy; Toll-Like Receptor 4 | 2019 |