Compounds > isoproterenol

isoproterenol and kn 93

isoproterenol has been researched along with kn 93 in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (75.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdel-Latif, AA; Ansari, HR; Husain, S1
Altschuld, RA; Cheng, Y; Dumitrescu, C; Efimov, IR; Narayan, P1
Anderson, ME; Colbran, RJ; Dzhura, I; Olson, EN; Passier, R; Roden, DM; Temple, J; Trimble, R; Wu, Y; Zhang, R; Zhang, W1
Lehnart, SE; Marks, AR; Reiken, SR; Wehrens, XH1
Cumbay, MG; Watts, VJ1
Chen, K; Chen, SR; Cheng, H; Obayashi, M; Shimoni, Y; Ter Keurs, H; Walsh, MP; Xiao, B; Yang, D; Zhong, G1
Anderson, ME; Bass, M; Colbran, RJ; Gomez, RJ; Grueter, CE; Guan, X; Kannankeril, P; Khoo, MS; Li, J; Madu, EC; Mendes, L; Ni, G; Oddis, CV; Olson, EN; Singh, MV; Wadzinski, BE; Wu, Y; Yang, J; Yang, Y; Zhang, R1
Bers, DM; Curran, J; Hinton, MJ; Ríos, E; Shannon, TR1
Chen, SA; Chen, YC; Chen, YJ; Lin, CI; Lo, LW; Wongcharoen, W1
Donoso, P; Ferrero, P; Mattiazzi, A; Mundiña-Weilenmann, C; Said, M; Sánchez, G; Valverde, C; Vittone, L1
Booth, SW; Grace, AA; Gurung, IS; Heathcote, JC; Hothi, SS; Huang, CL; Skepper, JN; Zhang, Y1
Jing, L; Liu, C; Wang, H; Wong, TM; Wu, G; Yang, J; Yang, Y1
Abdellatif, M; Belevych, AE; Elton, TS; Feldman, DS; Györke, S; Kuhn, DE; Malana, GE; Martin, MM; Terentyev, D; Terentyeva, R1
Cheng, WT; Ma, Y; Wong, TM; Wu, S1
Abesser, M; Backs, J; Brown, JH; Grefe, C; Khabbazzadeh, S; Maier, LS; Maier, SK; Neef, S; Neumann, K; Olson, EN; Opiela, MK; Sag, CM; Wadsack, DP1
Janssen, PM; Roof, SR; Shannon, TR; Ziolo, MT1
Belevych, AE; Billman, GE; Bonilla, IM; Carnes, CA; Gyorke, I; Györke, S; Ho, HT; Terentyev, D; Terentyeva, R1
Antoons, G; Beekman, JD; Bourgonje, VJ; de Windt, LJ; Houtman, MJ; Miedema, LF; Schoenmakers, M; Sipido, K; van der Nagel, R; van Veen, TA; Vos, MA1
Chen, Y; Huang, C; Huang, Y; Li, R; Liu, T; Tang, Y; Wang, D; Wang, T; Wang, X1
Cheng, J; He, Q; Wang, Y1

Other Studies

20 other study(ies) available for isoproterenol and kn 93

ArticleYear
Activation of p42/p44 mitogen-activated protein kinase and contraction by prostaglandin F2alpha, ionomycin, and thapsigargin in cat iris sphincter smooth muscle: inhibition by PD98059, KN-93, and isoproterenol.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Blotting, Western; Calcium-Transporting ATPases; Cats; Densitometry; Dinoprost; Enzyme Activation; Enzyme Inhibitors; Flavonoids; In Vitro Techniques; Ionomycin; Ionophores; Iris; Isoproterenol; Mitogen-Activated Protein Kinase 1; Muscle Contraction; Muscle, Smooth; Sulfonamides; Thapsigargin

2001
Phase I and phase II of short-term mechanical restitution in perfused rat left ventricles.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Benzylamines; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Enzyme Inhibitors; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Perfusion; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcolemma; Sarcoplasmic Reticulum; Sulfonamides; Systole; Thapsigargin; Time Factors; Vasodilation; Ventricular Function, Left

2002
Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy.
    Circulation, 2002, 09-03, Volume: 106, Issue:10

    Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Benzylamines; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Electric Conductivity; Electrocardiography; Enzyme Inhibitors; Humans; Isoproterenol; Mice; Mice, Transgenic; Myocardium; Phenotype; Signal Transduction; Sulfonamides

2002
Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor.
    Circulation research, 2004, Apr-02, Volume: 94, Issue:6

    Topics: Adrenergic beta-Agonists; Amino Acid Sequence; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cardiac Pacing, Artificial; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Heart Failure; Heart Rate; Humans; Isoproterenol; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardial Infarction; Myocardium; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Rabbits; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Ryanodine Receptor Calcium Release Channel; Sequence Alignment; Sequence Homology, Amino Acid; Sulfonamides; Tacrolimus Binding Proteins; Ultrasonography

2004
Galphaq potentiation of adenylate cyclase type 9 activity through a Ca2+/calmodulin-dependent pathway.
    Biochemical pharmacology, 2005, Apr-15, Volume: 69, Issue:8

    Topics: Adenylyl Cyclases; Benzylamines; Calcium; Calmodulin; Cell Line; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Indoles; Isoproterenol; Maleimides; Mutation; Protein Kinase C; Receptors, Muscarinic; Receptors, Serotonin, 5-HT2; Signal Transduction; Sulfonamides; Thapsigargin

2005
Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts.
    The Biochemical journal, 2006, May-15, Volume: 396, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Benzylamines; Blotting, Western; Calcium Signaling; Carrier Proteins; Cell Line; Cyclic AMP-Dependent Protein Kinases; Heart Failure; Humans; Ion Channel Gating; Ion Transport; Isoproterenol; Kidney; Marine Toxins; Mice; Myocytes, Cardiac; Oxazoles; Peptide Fragments; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Rabbits; Rats; Recombinant Fusion Proteins; Ryanodine Receptor Calcium Release Channel; Sodium-Calcium Exchanger; Staurosporine; Structure-Activity Relationship; Sulfonamides; Transfection

2006
Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy.
    Circulation, 2006, Sep-26, Volume: 114, Issue:13

    Topics: Amino Acid Sequence; Animals; Animals, Newborn; Apoptosis; Arrhythmias, Cardiac; Benzylamines; Calcineurin; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Death, Sudden, Cardiac; Disease Models, Animal; Enzyme Induction; Hypertrophy, Left Ventricular; Isoproterenol; Mice; Mice, Transgenic; Molecular Sequence Data; Myocardial Contraction; Myocytes, Cardiac; Peptide Fragments; Rats; RNA, Messenger; Sulfonamides; Ventricular Dysfunction, Left

2006
Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase.
    Circulation research, 2007, Feb-16, Volume: 100, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Calcium; Calcium Channels, L-Type; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diastole; Heart Failure; Isoproterenol; Isoquinolines; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Peptides; Phosphorylation; Protein Processing, Post-Translational; Rabbits; Receptors, Adrenergic, beta; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Signal Transduction; Sulfonamides; Tetracaine

2007
Calmodulin kinase II inhibition prevents arrhythmic activity induced by alpha and beta adrenergic agonists in rabbit pulmonary veins.
    European journal of pharmacology, 2007, Oct-01, Volume: 571, Issue:2-3

    Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Kinetics; Phenylephrine; Protein Kinase Inhibitors; Pulmonary Veins; Rabbits; Sulfonamides

2007
Ca2+/calmodulin kinase II increases ryanodine binding and Ca2+-induced sarcoplasmic reticulum Ca2+ release kinetics during beta-adrenergic stimulation.
    Journal of molecular and cellular cardiology, 2007, Volume: 43, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Isoproterenol; Isoquinolines; Kinetics; Male; Nifedipine; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum; Sulfonamides

2007
Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 457, Issue:2

    Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Benzylamines; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiac Pacing, Artificial; Cyclic AMP; Female; Guanine Nucleotide Exchange Factors; Heart Ventricles; Homeostasis; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Mice; Models, Cardiovascular; Myocytes, Cardiac; Perfusion; Protein Kinase Inhibitors; Refractory Period, Electrophysiological; Sulfonamides; Tachycardia, Ventricular; Time Factors

2008
kappa-Opioid receptor stimulation inhibits augmentation of Ca(2+) transient and hypertrophy induced by isoprenaline in neonatal rat ventricular myocytes - Role of CaMKIIdelta(B).
    European journal of pharmacology, 2008, Oct-24, Volume: 595, Issue:1-3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Benzylamines; Calcium Channel Blockers; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Nucleus; Cell Size; Cells, Cultured; Hypertrophy; Isoproterenol; Myocytes, Cardiac; Naltrexone; Narcotic Antagonists; Propranolol; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Opioid, kappa; Sulfonamides; Verapamil

2008
miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2.
    Circulation research, 2009, Feb-27, Volume: 104, Issue:4

    Topics: Adenoviridae; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Benzylamines; Calcium Channels, L-Type; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Genetic Vectors; Isoproterenol; Membrane Potentials; Mice; MicroRNAs; Myocardial Contraction; Myocytes, Cardiac; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 2; Rats; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sulfonamides; Time Factors; Transduction, Genetic

2009
Oestrogen confers cardioprotection by suppressing Ca2+/calmodulin-dependent protein kinase II.
    British journal of pharmacology, 2009, Volume: 157, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Benzylamines; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Disease Models, Animal; Down-Regulation; Drug Implants; Estrogens; Female; Isoproterenol; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Ovariectomy; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Recovery of Function; Sulfonamides

2009
Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure.
    Circulation. Heart failure, 2009, Volume: 2, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Benzylamines; Calcium; Calcium Channels, L-Type; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Heart Failure; Isoproterenol; Membrane Potentials; Mice; Mice, Knockout; Mice, Transgenic; Myocytes, Cardiac; Protein Kinase Inhibitors; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sulfonamides; Time Factors

2009
Effects of increased systolic Ca²⁺ and phospholamban phosphorylation during β-adrenergic stimulation on Ca²⁺ transient kinetics in cardiac myocytes.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:4

    Topics: Adenosine Triphosphatases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Benzylamines; Blotting, Western; Calcium; Calcium Signaling; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Enzyme Activation; In Vitro Techniques; Isoproterenol; Kinetics; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Phosphorylation; Sarcoplasmic Reticulum; Serine; Sulfonamides

2011
Shortened Ca2+ signaling refractoriness underlies cellular arrhythmogenesis in a postinfarction model of sudden cardiac death.
    Circulation research, 2012, Feb-17, Volume: 110, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Caffeine; Calcium Channel Agonists; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiac Pacing, Artificial; Death, Sudden, Cardiac; Disease Models, Animal; Dogs; Excitation Contraction Coupling; Female; Isoproterenol; Male; Myocardial Infarction; Myocytes, Cardiac; Oxidation-Reduction; Phosphorylation; Protein Kinase Inhibitors; Reaction Time; Reducing Agents; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sulfonamides; Time Factors; Tiopronin; Ventricular Fibrillation

2012
Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog.
    Heart rhythm, 2012, Volume: 9, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Atrioventricular Block; Benzylamines; Calcineurin; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomyopathy, Hypertrophic; Cyclosporine; Disease Models, Animal; Dogs; Isoproterenol; Long QT Syndrome; Myocytes, Cardiac; Patch-Clamp Techniques; Phenethylamines; Phenotype; Phosphorylation; Random Allocation; Sulfonamides; Ventricular Remodeling

2012
Calmodulin kinase II inhibitor regulates calcium homeostasis changes caused by acute β-adrenergic receptor agonist stimulation in mouse ventricular myocytes.
    In vitro cellular & developmental biology. Animal, 2016, Volume: 52, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Calcium; Calcium Channels, L-Type; Calcium Signaling; Carrier Proteins; Homeostasis; Intracellular Signaling Peptides and Proteins; Isoproterenol; Mice; Myocardial Contraction; Myocytes, Cardiac; Patch-Clamp Techniques; Protein Kinase Inhibitors; Sulfonamides

2016
Chronic CaMKII inhibition reverses cardiac function and cardiac reserve in HF mice.
    Life sciences, 2019, Feb-15, Volume: 219

    Topics: Animals; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Echocardiography; Electrocardiography; Heart; Heart Failure; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Sulfonamides; Ventricular Function, Left

2019