isoproterenol has been researched along with guanosine triphosphate in 422 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 298 (70.62) | 18.7374 |
| 1990's | 102 (24.17) | 18.2507 |
| 2000's | 19 (4.50) | 29.6817 |
| 2010's | 2 (0.47) | 24.3611 |
| 2020's | 1 (0.24) | 2.80 |
| Authors | Studies |
|---|---|
| Lefkowitz, RJ; Mukherjee, C | 1 |
| Birnbaumer, L; Bockaert, J; Duran, JM; Hunzicker-Dunn, M; Yang, PC | 1 |
| Anderson, HJ; Gilman, AG; Haga, T; Ross, EM | 1 |
| Ahn, HS; Makman, MH | 1 |
| Drummond, GI; Nambi, P | 1 |
| Christophe, J; Dehaye, J; Winand, J | 1 |
| Lin, C; Lin, MC; Whitlock, JP | 1 |
| Lesko, L; Marinetti, GV | 1 |
| Caron, MG; Lefkowitz, RJ | 2 |
| Hupka, AL; Sweat, FW; Wincek, TJ | 1 |
| Bennett, V; Cuatrecasas, P; Jacobs, S | 2 |
| Bennett, V; Cuatrecasas, P; Mong, L | 1 |
| Johnson, DG; Thompson, WJ; Williams, RH | 1 |
| Berkowitz, BA; Blume, AS; Cohen, ML | 1 |
| Stolc, V | 1 |
| Bockaert, J; Lucas, M | 1 |
| Biltonen, RL; Gilman, AG; Maguire, ME; Ross, EM; Sturgill, TW | 1 |
| Helmreich, EJ; Pfeuffer, T | 2 |
| Cassel, D; Selinger, Z | 3 |
| Franklin, TJ; Twose, PA | 1 |
| Gilman, AG; Ross, EM | 1 |
| Bourne, HR; Johnson, GL | 1 |
| Henneberry, RC; Smith, CC; Tallman, JF | 1 |
| Besch, HR; Fleming, JW; Jones, LR; McConnaughey, MM; Strawbridge, RA; Watanabe, AM | 1 |
| Anderson, RG; Johansson, SR | 1 |
| Bird, SJ; Maguire, ME | 1 |
| Johnson, GS; Mukku, VR | 1 |
| Burgess, WH; Gilman, AG; Howlett, AC; Kretsinger, RH | 1 |
| Fischer, J; Sharp, GW | 1 |
| Anderson, WB; Jaworski, CJ | 1 |
| Harden, TK; Perkins, JP; Su, YF | 1 |
| Hegstrand, LR; Minneman, KP; Molinoff, PB | 1 |
| DeLean, A; Hickey, AR; Lefkowitz, RJ; Limbird, LE; Pike, LJ | 1 |
| Cooper, DM; Lin, MC; Rodbell, M; Schlegel, W | 1 |
| Bourne, HR; Farfel, Z; Johnson, GL; Kaslow, HR | 1 |
| Korenman, SG; Krall, JF | 1 |
| Anderson, WB; Johnson, GS; Mukku, VR | 2 |
| Narayanan, N; Sulakhe, PV | 2 |
| Hickey, AR; Lefkowitz, RJ; Limbird, LE | 1 |
| Cassel, D; Eckstein, F; Levkovitz, H; Lowe, M; Selinger, Z | 1 |
| Bhalla, RC; Habhab, O; Sharma, RV | 1 |
| Gilman, AG; Schwarzmeier, JD | 1 |
| Palmer, GC; Palmer, SJ | 1 |
| Josephson, I; Sperelakis, N | 1 |
| Bennett, V; Cuatrecasas, P | 2 |
| Aurbach, GD; Brown, EM; Fedak, SA; Spiegel, AM; Woodard, CJ | 1 |
| Ahn, HS; Demirjian, C; Makman, MH; Mishra, RK | 1 |
| Pfeuffer, T | 1 |
| Cuatrecasas, P; Jacobs, S; Rodgers, N | 1 |
| Caron, MG; Lefkowitz, RJ; Mullikin, D | 1 |
| Levitzki, A; Sevilla, N; Steer, ML | 1 |
| Sweat, FW; Wincek, TJ | 1 |
| Orly, J; Schramm, M | 1 |
| Cuatrecasas, P; Pasternak, GW; Tell, GP | 1 |
| Lefkowitz, RJ | 2 |
| Coraboeuf, E; Couétil, JP; Deroubaix, E; Le Grand, B | 1 |
| Freeman, LC; Kass, RS; Kwok, WM | 1 |
| Insel, PA; Jasper, JR; Leiber, D; Ransnäs, LA | 1 |
| Izawa, T; Komabayashi, T; Mochizuki, T; Suda, K; Tsuboi, M | 1 |
| Collins, D; Cotter, T; Kilfeather, SA; McCormack, P; O'Malley, K | 1 |
| Barber, DL; Ganz, MB | 1 |
| Canioni, P; Labouesse, J; Merle, M; Pianet, I | 1 |
| Labouesse, J; Merle, M; Valeins, H | 1 |
| Green, SA; Holt, BD; Liggett, SB | 1 |
| Gallacher, DV; Sasaki, T | 1 |
| Graziano, MP; Kotlikoff, MI; Kume, H | 1 |
| Birnbaumer, L; Codina, J; Estes, MK; Evans, T; Graf, R; Ho, YK; Mattera, R | 1 |
| Hussain, T; Mustafa, SJ | 1 |
| Clusin, WT; Gunn, MD; Lauer, MR | 1 |
| Bangert, M; Beyer, T; Niroomand, F; Rauch, B | 1 |
| Ambudkar, IS; Baum, BJ; Hiramatsu, Y | 1 |
| Morrison, JF; Nimmo, AJ; Whitaker, EM | 1 |
| Day, R; Farnsworth, CL; Feig, LA; Hildebrandt, JD | 1 |
| Hayashi, Y; Inagaki, M; Murayama, Y; Nishimoto, I; Ogata, E; Okamoto, T | 1 |
| Furukawa, T; Habuchi, Y; Tanaka, H; Tsujimura, Y | 1 |
| Gammichia, J; Humphreys-Beher, MG; Nakagawa, Y; Purushotham, KR; Schneyer, CA | 1 |
| Adolfs, MJ; Bonta, IL; Houdijk, AP; Van Leeuwen, PA | 1 |
| Brighenti, L; Fabbri, E; Ottolenghi, C | 1 |
| Fujinami, H; Izawa, T; Komabayshi, T; Nakamura, T; Suda, K; Tsuboi, M | 1 |
| Mooradian, AD; Scarpace, PJ | 2 |
| Ikezawa, K; Kikkawa, H; Naito, K | 1 |
| Kilgour, E; Larner, J; Luttrell, L; Romero, G | 1 |
| Buja, LM; DeBeltz, D; Muntz, KH; Shaul, PW | 1 |
| Drímal, J | 1 |
| Avissar, S; Murphy, DL; Schreiber, G | 1 |
| Brown, LA | 1 |
| Nakamura, T; Nomura, J; Tsujimura, R | 1 |
| Buja, LM; Farrar, MA; Kinane, B; Magness, RR; Shaul, PW | 1 |
| Houslay, MD; Milligan, G; Palmer, T; Strassheim, D | 1 |
| Houslay, MD; Palmer, TM | 1 |
| Fujita, M; Hanai, H; Matsunaga, T; Natsukari, N | 1 |
| Klim, CM; LaNoue, KF; Martin, LF; Vannucci, SJ | 1 |
| Hertel, C; Murphy, EA; Nunnally, MH; Perkins, JP; Ross, EM; Wong, SK | 1 |
| Bourne, HR; Jones, DT; Masters, SB; Reed, RR | 1 |
| Geisler, A; Klysner, R; Mørk, A | 1 |
| Avissar, S; Schreiber, G | 1 |
| Buja, LM; Muntz, KH; Shaul, PW | 1 |
| Buckenmeyer, PJ; Dax, EM; Goldfarb, AH; Partilla, JS; Piñeyro, MA | 1 |
| Breckon, R; Dixon, BS; Fortune, J; Linas, SL; Marzec-Calvert, R; Stewart, JM; Vavrek, RJ | 1 |
| Houslay, MD; Milligan, G; Strassheim, D | 1 |
| Abrahamsson, T; Nerme, V; Vauquelin, G | 1 |
| Brown, AM; Kirsch, GE; Schubert, B; Vandongen, AM | 2 |
| Ascoli, M; Hafez, MM | 1 |
| Arango, V; Ernsberger, P; Mann, JJ; Reis, DJ | 1 |
| Hesslinger, B; McDonald, TF; Pelzer, D; Shuba, YM; Trautwein, W | 1 |
| Brown, EM; Leboff, MS; Oetting, M | 1 |
| Ramos-Franco, J; Stefani, E; Toro, L | 1 |
| Aulakh, CS; Avissar, S; Murphy, DL; Schreiber, G; Wozniak, KM | 1 |
| Freissmuth, M; Nanoff, C; Schütz, W; Selzer, E; Tuisl, E | 1 |
| Brand, JG; Kare, MR; Katz, Y; Naim, M | 1 |
| Ekstrom, RC; Hunzicker-Dunn, M | 1 |
| Fukuda, N; Hatano, M; Honda, M; Izumi, Y; Minato, M; Soma, M | 1 |
| Donovan, LA; Liang, BT | 1 |
| Bulargina, TV; Popov, KM; Severin, ES | 1 |
| Daniel, K; Lefkowitz, RJ; Sibley, DR; Strader, CD | 1 |
| Birnbaumer, L; Brown, AM; Codina, J; Imoto, Y; Reeves, JP; Yatani, A | 1 |
| Gutierrez, GE; Katz, MS; Mundy, GR | 1 |
| de Mazancourt, P; Giot, J; Giudicelli, Y; Lacasa, D | 1 |
| Birnbaumer, L; Brown, AM; Codina, J; Imoto, Y; Mattera, R; Yatani, A | 1 |
| Fukuda, N; Hatano, M; Honda, M | 1 |
| Audigier, Y; Bockaert, J; Journot, L | 1 |
| Burke, DN; Fleming, N; Sliwinski-Lis, E | 1 |
| Jacobson, KL; Singh, JC; Watson, EL | 1 |
| Creese, I; Riva, MA | 1 |
| Barrett, D; Breslau, NA; Downs, RW; Molinoff, PB; Wax, MB | 1 |
| Beiderman, B; Bourne, HR; Chang, FH; Chi, MH; Lopez, NG; Masters, SB; Miller, RT | 1 |
| Dees, C; Hekman, M; Münch, G; Palm, D | 1 |
| Dereski, MO; Diglio, C; Giacomelli, F; Grammas, P; Wiener, J | 1 |
| Gierschik, P; Herrmann, E; Jakobs, KH | 1 |
| Hintze, TH; Homcy, CJ; Nejima, J; Susanni, EE; Uemura, N; Vatner, DE; Vatner, SF | 1 |
| Frey, MJ; Lanoce, V; Molinoff, PB; Wilson, JR | 1 |
| Iijima, T; Taira, N | 1 |
| Keenan, AK; Murray, R | 1 |
| Hindemith-Augustsson, A; Johansson, LH; Karg, E; Rorsman, H; Rosengren, E | 1 |
| Geisler, A; Mørk, A | 1 |
| Labouesse, J; Pianet, I; Teissié, J; Volker, TT | 1 |
| Grogan, DM; Hatjis, CG; Koritnik, DR | 1 |
| Grogan, DM; Hatjis, CG | 1 |
| Anderson, SM; Schaeffer, JM | 1 |
| Dobson, JG; Frohloff, N; LaMonica, DA | 1 |
| Boulet, AP; Fortier, MA; Lambert, RD | 2 |
| Miyakoda, G; Nakamura, T; Takisawa, H; Yoshida, A | 1 |
| Boulet, AP; Fortier, MA | 1 |
| Kimura, N; Shimada, N | 1 |
| Antonicelli, F; Haye, B; Jacquemin, C; Lambert, B | 1 |
| Crews, A; Hatjis, CG | 1 |
| Attramadal, H; Eikvar, L; Hansson, V | 1 |
| Bode, DC; Molinoff, PB | 1 |
| Resek, JF; Ruoho, AE | 1 |
| García-Sáinz, JA; Hernández-Sotomayor, SM; Macías-Silva, M; Plebañski, M | 1 |
| Ramkumar, V; Stiles, GL | 1 |
| Brighenti, L; Fabbri, E; Gavioli, ME; Ottolenghi, C; Puviani, AC | 1 |
| Bell, JD; Brunton, LL; Buxton, IL | 1 |
| Abramson, SN; Hoyer, D; Molinoff, PB; Reynolds, EE | 1 |
| Bollack, C; Helwig, JJ; Judes, C; Mandel, P | 1 |
| Koike, K; Takayanagi, I | 1 |
| Schacht, J | 1 |
| Barrett, DA; Molinoff, PB; Neve, KA | 1 |
| Bell, JD; Brunton, LL | 2 |
| Koshiura, R; Matsunaga, T; Miyamoto, K; Sanae, F | 1 |
| Ijzerman, A; Nerme, V; Severne, Y; Timmerman, H; Vauquelin, G | 1 |
| Beiderman, B; Bourne, HR; Lopez, NG; Masters, SB; Miller, RT; Ramachandran, J; Sullivan, KA | 1 |
| Bier-Laning, CM; Gerber, JG; Miller, JA; Nies, AS; Parker, DC; Zahniser, NR | 1 |
| Benovic, JL; Birnbaumer, L; Caron, MG; Cerione, RA; Codina, J; Gierschik, P; Lefkowitz, RJ; Somers, R; Spiegel, AM; Staniszewski, C | 2 |
| Hatjis, CG | 2 |
| Kitamura, Y; Nomura, Y | 1 |
| Delavier-Klutchko, C; Durieu-Trautmann, O; Hoebeke, J; Strosberg, AD | 1 |
| Kirilovsky, J; Schramm, M; Selinger, Z; Steiner-Mordoch, S | 1 |
| Bilargina, TV; Popov, KM; Severin, ES | 1 |
| Attramadal, H; Hansson, V; Jahnsen, T; Le Gac, F | 2 |
| Bilezikian, JP; Feigin, AS; Owens, JM; Shane, E; Yeh, M | 1 |
| Frazer, A; O'Donnell, JM | 1 |
| Arinze, IJ; Graham, SM; Kawai, Y; Whitsel, C | 1 |
| Lang, PH; Lemmer, B | 1 |
| Jagadeesh, G; Phan, NT; Sulakhe, PV | 1 |
| Beaufort, P; Camus, JC; Christophe, J; Clinet, M; Devos, C; Nokin, P; Robberecht, P; Schoenfeld, P; Waelbroeck, M | 1 |
| Kassis, S | 1 |
| Insel, PA; Mahan, LC | 1 |
| Giudicelli, Y; Leneveu, MC; Pecquery, R | 1 |
| Fishman, PH; Rebois, RV | 1 |
| Deli, E; Kiss, Z | 1 |
| Birnbaumer, L; Caron, MG; Cerione, RA; Codina, J; Gierschik, P; Lefkowitz, RJ; Somers, RL; Spiegel, AM; Staniszewski, C | 1 |
| Narayanan, N; Tucker, L | 1 |
| Okada, F; Tokumitsu, Y; Ui, M | 2 |
| Anand-Srivastava, MB; Cantin, M | 1 |
| Harding, SE; Harris, P | 1 |
| Agli, B; Giudicelli, Y; Lacasa, D | 2 |
| Gagne, B; Labrie, F; Poyet, P | 1 |
| Anand-Srivastava, MB; Cantin, M; Srivastava, AK | 1 |
| Katada, T; Murakami, T; Yasuda, H | 1 |
| Cooney, D; Dees, C; Hekman, M; Holzhöfer, A; Keenan, AK | 1 |
| Boege, F; Cooney, D; Hekman, M; Helmreich, EJ; Jürss, R; Keenan, AK | 1 |
| Galper, JB; Hellmich, MR; Liang, BT; Neer, EJ | 1 |
| Küttner, I; Schulze, W; Will-Shahab, L | 1 |
| Bilezikian, JP; Chow, YK; Steinberg, SF | 1 |
| Chang, PP; Holmes, RK; Moss, J; Twiddy, EM | 1 |
| Casey, PJ; Gilman, AG; Graziano, MP | 1 |
| Insel, PA; Ransnäs, LA | 1 |
| Fortier, MA; Grasso, F; Guilbault, LA | 1 |
| Bégin-Heick, N; Coleman, DL | 1 |
| Bégin-Heick, N; Welsh, J | 1 |
| Fujii, AM; Homcy, CJ; Lee, DL; Longabaugh, JP; Schwarz, KR; Vatner, DE; Vatner, SF | 1 |
| Frazer, A; Offord, SJ; Ordway, GA | 1 |
| Avissar, S; Belmaker, RH; Danon, A; Schreiber, G | 1 |
| Figgs, LW | 1 |
| Kaplan, RS; Rasenick, MM | 1 |
| Krall, JF | 1 |
| Christophe, J; Dehaye, JP; Lambert, M; Mayer, R; Poloczek, P; Soukias, Y; van Bogaert, P; Winand, J | 1 |
| Guibbolini, M; Lahlou, B | 1 |
| Attramadal, H; Erichsen, AA; Hansson, V; Jahnsen, T | 1 |
| Giri, SN; Robison, TW | 1 |
| Brooker, G; Pedone, C | 1 |
| Jacobson, KL; Watson, EL | 1 |
| McDonald, JM; Mooney, RA | 1 |
| Cho, YH; Housman, A; Weiss, RM; Wheeler, MA | 1 |
| Bégin-Heick, N | 2 |
| Camus, JC; Chatelain, P; Christophe, J; Robberecht, P; Waelbroeck, M | 1 |
| Galper, JB; Liang, BT | 1 |
| Gierschik, P; Spiegel, AM | 1 |
| Anand-Srivastava, MB; Cantin, M; Johnson, RA; Picard, S | 1 |
| Hansson, V; Jahnsen, T; Smith, AJ | 1 |
| Arnstein, HR; Bonanou-Tzedaki, SA; Setchenska, MS | 1 |
| Aakvaag, A; Torjesen, PA | 1 |
| Carney, JM; Chandler, MJ; Hornbrook, KR | 1 |
| Hodgins, DS; Kuo, JF; Kuo, WN | 1 |
| Howell, SL; Montague, W | 1 |
| Böhme, E; Jakobs, KH; Schultz, G; Schultz, K | 1 |
| Chader, GJ; Fletcher, RT; Herz, L | 1 |
| Aurbach, GD; Spiegel, AM | 1 |
| Ikarashi, A; Nohara, H | 1 |
| Aurbach, GD; Bilezikian, JP | 1 |
| Johnson, GL; Kelleher, DJ; Pessin, JE; Ruoho, AE | 1 |
| Attramadal, H; Frøysaker, T; Golf, S; Hansson, V; Jahnsen, T | 1 |
| Benovic, JL; Birnbaumer, L; Caron, MG; Cerione, RA; Codina, J; Lefkowitz, RJ; Neer, EJ; Sibley, DR; Winslow, J | 1 |
| Asano, T; Brandt, DR; Pedersen, SE; Ross, EM | 1 |
| Cornett, LE; Hiller, C; Hough, A; Norris, JS; Popovich, KJ | 1 |
| Chirkov, IuIu; Malatsidze, MA; Serobian, GA; Sobolev, AS | 1 |
| Hertel, C; Perkins, JP | 1 |
| Asano, T; Pedersen, SE; Ross, EM; Scott, CW | 1 |
| Asano, T; Ross, EM | 1 |
| Kilpatrick, BF; Lefkowitz, RJ; Stiles, GL; Strasser, RH; Taylor, SR | 1 |
| Affolter, H; Hertel, C; Portenier, M; Staehelin, M | 1 |
| Aktories, K; Jakobs, KH; Minuth, M | 1 |
| Lai, E; Rosen, OM; Rubin, CS | 1 |
| Lefkowitz, RJ; Stiles, GL | 1 |
| Cerino, D; Kling, P; Lotti, VJ | 1 |
| Suidan, H; Tamir, A; Tolkovsky, AM | 1 |
| Brodde, OE; Karad, K; Reidemeister, JC; Rohm, N; Zerkowski, HR | 1 |
| Abramson, SN; Molinoff, PB | 1 |
| Asano, T; Gilman, AG; Katada, T; Ross, EM | 1 |
| Branscheid, D; Goretzki, PE; Roeher, HD; Wahl, RA | 1 |
| Lefkowitz, RJ; Nambi, P; Peters, JR; Sibley, DR | 1 |
| Koschel, K | 1 |
| Christian, CP; Cutler, LS | 1 |
| Kather, H; Zimmer, B | 1 |
| Camus, JC; Chatelain, P; Christophe, J; Gillet, L; Robberecht, P; Waelbroeck, M | 1 |
| Chen, TC; Cote, TE; Kebabian, JW | 1 |
| Aurbach, GD; Downs, RW; Reen, S; Singer, M; Spiegel, AM | 1 |
| Lad, PM; Nielsen, TB; Preston, MS; Rodbell, M | 1 |
| Nemecek, GM | 1 |
| Belman, S; Garte, SJ | 1 |
| Abramowitz, J; Birnbaumer, L; Bordelon-Riser, M; Iyengar, R | 1 |
| Charlton, RR; Jeffery, DR; Venter, JC | 1 |
| Cooper, DM; Rodbell, M; Schlegel, W | 1 |
| Johnston, CI; Woodcock, EA | 1 |
| Burns, TW; Langley, PE; Robison, GA; Terry, BE | 1 |
| Abramowitz, J; Birnbaumer, L; Blume, AJ; Bordelon-Riser, M; Iyengar, R | 1 |
| Lad, PM; Londos, C; Nielsen, TB; Preston, MS; Rodbell, M | 1 |
| Cote, TE; Grewe, CW; Kebabian, JW | 2 |
| Clark, GF; Smith, PB | 1 |
| Lefkowitz, RJ; Pike, LJ | 1 |
| Molinoff, PB; Pittman, RN | 1 |
| Bhat, MK; Birnbaumer, L; Iyengar, R; Riser, ME | 1 |
| Bernstein, KJ; Gangat, Y; Triner, L; Verosky, M; Vulliemoz, Y | 1 |
| Bockaert, J; Mauger, JP; Vassent, G | 1 |
| Abrass, IB; O'Connor, SW; Scarpace, PJ | 1 |
| Blecher, M; McHugh, EM; Reilly, TM | 1 |
| De Lean, A; Hoffman, BB; Kent, R; Lefkowitz, RJ; Limbird, L; Michel, T; Stadel, JM | 1 |
| Citri, Y; Eimerl, S; Korner, M; Neufeld, G; Schramm, M | 1 |
| Latzka, U; Lubec, G; Paietta, E; Schwarzmeier, JD; Simbruner, G | 1 |
| Burns, DL; Moss, J; Vaughan, M | 1 |
| Bourne, HR; Brickman, AS; Brothers, VM; Farfel, Z; Kaslow, HR | 1 |
| Greenberg, ML; Malbon, CC | 1 |
| Amano, T; Katada, T; Ui, M | 1 |
| Johnson, GS; Kimura, N | 1 |
| Blecher, M; Reilly, TM | 1 |
| de Mazancourt, P; Giudicelli, Y; Thotakura, NR | 1 |
| Cote, TE; Eskay, RL; Frey, EA; Grewe, CW; Kebabian, JW; Munemura, M; Stoof, JC; Tsuruta, K | 1 |
| Mirkin, BL; Schumacher, WA; Sheppard, JR | 1 |
| Nahorski, SR | 1 |
| Hirai, M; Komoriyama, K; Kouyama, H; Shima, S | 2 |
| André, C; Cech, SY; Maguire, ME; Strosberg, AD; Vauquelin, G | 1 |
| Tkachuk, VA | 1 |
| Cote, TE; Frey, EA; Grewe, CW; Kebabian, JW | 1 |
| Hashizume, K; Ichikawa, K; Kobayashi, M | 1 |
| Kuriyama, K; Muramatsu, M; Ohkuma, S; Tamura, J | 1 |
| Gill, DM; Meren, R | 1 |
| Piekarska, T | 1 |
| Korner, M; Neufeld, G; Schramm, M; Steiner, S | 1 |
| Hamel, FG; Luft, FC; Queener, SF | 1 |
| Goldman, ME; Kebabian, JW; Miyazaki, K | 1 |
| Fishman, PH; Henneberry, RC; Kassis, S | 1 |
| Arnstein, HR; Setchenska, MS | 2 |
| Smith, PB | 1 |
| Baldenkov, GN; Panchenko, MP; Tkachuk, VA | 1 |
| de Vries, K; Kauffman, HF; Koëter, GH; Meurs, H | 1 |
| Attramadal, H; Hansson, V; Jahnsen, T | 1 |
| Blecher, M; Gordon, JC | 1 |
| Hynie, S; Mourek, J; Mühlbachová, E; Wenke, M | 1 |
| Panchenko, MP; Tkachuk, VA | 1 |
| Halvorsen, SW; Nathanson, NM | 1 |
| Brown, LB; Herman, CA | 1 |
| Gagné, B; Labrie, F; Lefèvre, G; Meunier, H | 1 |
| Fain, JN; Hudson, TH | 1 |
| Fain, JN; Gárciá-Sáinz, JA; Mills, I; O'Donnell, CJ | 1 |
| Hosey, MM; McMahon, KK; Schimmel, RJ | 1 |
| Bernstein, KJ; Triner, L; Verosky, M | 1 |
| Harding, SE; Harris, P; Leclerc, L | 1 |
| Asch, RH; Rojas, FJ | 1 |
| Enomoto, K; Gill, DM | 1 |
| Fortier, M; Krall, JF | 1 |
| Abrass, IB; Scarpace, PJ | 1 |
| Rodan, GA; Rodan, SB | 1 |
| Jensen, A; Rinard, GA | 1 |
| Chambard, M; Mauchamp, J; Verrier, B | 1 |
| Cote, TE; Eskay, RL; Grewe, CW; Kebabian, JW; Stoof, JC; Tsuruta, K | 1 |
| Bhalla, RC; Sharma, RV | 1 |
| Korenman, SG; Krall, JF; Leshon, SC | 1 |
| Chatelain, P; Christophe, J; De Neef, P; Deschodt-Lanckman, M; König, W; Robberecht, P | 1 |
| Avdonin, PV; Panchenko, MP; Tkachuk, VA | 1 |
| Kather, H | 1 |
| Bitonti, AJ; Moss, J; Tandon, NN; Vaughan, M | 1 |
| Fishman, PH; Hagmann, J | 1 |
| Abramowitz, J; Birnbaumer, L; Iyengar, R | 1 |
| Attie, MF; Aurbach, GD; Brown, EM; Gardner, DG; Spiegel, AM | 1 |
| Cox, RH; Shi, QY | 1 |
| Bouet-Alard, R; Cohen-Tannoudji, J; Legrand, C; Limon-Boulez, I; Maltier, JP; Mhaouty, S | 1 |
| Diederich, M; Eschenhagen, T; Kluge, SH; Magnussen, O; Mene, U; Müller, F; Schmitz, W; Scholz, H; Sent, U; Weil, J | 1 |
| Chorev, M; Halifa, I; Kleinhaus, S; Selinger, Z; Zor, T | 1 |
| Hall, IP; Kotlikoff, MI; Kume, H; Takagi, K; Washabau, RJ | 1 |
| Inagaki, C; Kitagawa, K; Morita, M; Omori, K; Uriu, T; Yasukura, T | 1 |
| Ehlert, FJ; Thomas, EA | 1 |
| Fenoglio-Preiser, C; Sperelakis, N; Xiong, Z | 1 |
| Lau, C; Seidler, FJ; Slotkin, TA | 1 |
| Audigier, Y; Bornancin, F; Chabre, M | 1 |
| Hayashi, H; Hong, RB; Ikegaya, T; Kaneko, M; Kobayashi, A; Masuda, H; Yamazaki, N | 1 |
| Janssens, PA; Kleineke, JW | 1 |
| Etgen, AM; Makman, MH; Morris, SA; Ungar, S | 1 |
| Hartzell, HC; Parsons, TD | 1 |
| Butkerait, P; Friedman, E; Wang, HY | 1 |
| Haslam, RJ; Lee, RM; Maurice, DH | 1 |
| Koshland, DE; Morimoto, BH | 1 |
| Cortinovis, C; Klimek, F; Nogueira, E | 1 |
| Somasundaram, B; Tregear, RT | 1 |
| Humphreys-Beher, MG; Nakagawa, Y; Wang, PL | 1 |
| Galas, MC; Harden, TK | 1 |
| Hall, JL; Hamilton, CD; Roth, DA; Stanley, WC; White, CD | 1 |
| Reithmann, C; von Scheidt, W; Werdan, K | 1 |
| Giannuzzi, CE; Seidler, FJ; Slotkin, TA | 1 |
| Bick, RJ; Buja, LM; King, TW; LeMaistre, A; Liao, JP; McMillin, JB | 1 |
| Seidler, FJ; Slotkin, TA; Zeiders, JL | 1 |
| Bourne, HR; Farfel, Z; Iiri, T | 1 |
| Jakobs, KH; Kübler, W; Mura, R; Niroomand, F; Rauch, B | 1 |
| Du, F; Quaegebeur, JM; Sun, LS | 1 |
| Clancy, J; Emala, CW; Hirshman, CA; Schears, G | 1 |
| Busto, R; Carmena, MJ; Carrero, I; Guijarro, LG; Juarranz, MG; Prieto, JC | 1 |
| Bouet-Alard, R; Legrand, C; Limon-Boulez, I; Maltier, JP; Mhaouty-Kodja, S | 1 |
| Berlot, CH; Grishina, G | 1 |
| Barber, MD; Hirai, K; Hussey, HJ; Price, SA; Tisdale, MJ | 1 |
| Cohen-Tannoudji, J; Coudouel, N; Lécrivain, JL; Legrand, C; Maltier, JP; Robin, MT | 1 |
| McCook, EC; Seidler, FJ; Slotkin, TA; Zhang, J | 1 |
| Nelson, CS; Neve, KA; Wiens, BL | 1 |
| Kobilka, BK; Lam, VT; Lee, TW; Seifert, R | 1 |
| Chen, C; Eguchi, T; Ishida, H; Ishikawa, Y; Skowronski, MT | 1 |
| Emala, CW; Hirshman, CA; Kuhl, JS; Levitsky, HI; Lindeman, KS | 1 |
| Anand-Srivastava, MB; de Champlain, J; Marcil, J | 1 |
| Gether, U; Kobilka, BK; Seifert, R; Wenzel-Seifert, K | 1 |
| Egorova, A; Higashida, C; Higashida, H; Noda, M; Yokoyama, S; Zhang, JS; Zhong, ZG | 1 |
| Asai, K; Fujita, K; Higashida, H; Hotta, T; Kato, T | 1 |
| Bourin, MC; Crozatier, B; Germack, R; León-Velarde, F; Mohammadi, K; Richalet, JP | 1 |
| DeCostanzo, AJ; Hallagan, S; Liu, T; Liu, X; Malbon, CC; Moon, RT | 1 |
| Liu, HY; Seifert, R; Wenzel-Seifert, K | 1 |
| Hejnová, L; Ihnatovych, I; Kostrnová, A; Mares, P; Novotný, J; Svoboda, P | 1 |
| Groll, DH; Hanke, S; Liebmann, C; Nürnberg, B | 1 |
| Rasenick, MM; Yu, JZ | 1 |
| Liu, HY; Seifert, R | 1 |
| Hildebrandt, JD; Lanier, SM; Ribas, C; Sato, M; Takesono, A | 1 |
| Derkach, KV; Kuznetsova, LA; Pertseva, MN; Plesneva, SA; Shpakov, AO; Uspenskaia, ZI | 1 |
| Anderson, CM; Kilts, CD; Lachowicz, JE; Leonard, SK; Mailman, RB; Schulz, DW | 1 |
| Bolton, TB; Gordienko, DV; Tsvilovskyy, VV; Tsytsyura, YD; Zholos, AV | 1 |
| Derkach, KV; Kuznetsova, LA; Pertseva, MN; Plesneva, SA; Shpakov, AO; Shpakova, EA; Uspenskaia, ZI | 1 |
| Garrison, JC; Mayeenuddin, LH | 1 |
| Ahmad, U; Buhimschi, IA; Hall, G; Mason, C; Swaan, P; Weiner, CP | 1 |
| Herzig, S; Matthes, J; Rottlaender, D; Seifert, R; Vatner, SF | 1 |
| Kuznetsova, LA; Pertseva, MN; Plesneva, SA; Shpakov, AO | 1 |
| Bondareva, VM; Kuznetsova, LA; Pertseva, MN; Plesneva, SA; Shpakov, AO | 1 |
| Geduhn, J; Gille, A; Göttle, M; Höcherl, K; König, B; Seifert, R | 1 |
| Chen, ZH; Cho, WJ; Jena, BP; Lee, JS; Shin, L | 1 |
| Franco, M; Luton, F; Macia, E; Paleotti, O; Partisani, M | 1 |
| Dey, R; Eng, ET; Ernst, OP; Hite, RK; Huang, J; Huang, XY; Jordan, KD; Lee, MY; Liu, W; Meyerson, JR; Paknejad, N; Su, M; Walz, T; Williams, D; Zhang, Y; Zhu, L | 1 |
4 review(s) available for isoproterenol and guanosine triphosphate
| Article | Year |
|---|---|
Direct G-protein regulation of Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cattle; Dihydropyridines; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Humans; Isoproterenol; Thionucleotides | 1989 |
Adrenergic receptors: molecular mechanisms of clinically relevant regulation.
Topics: Adenylyl Cyclases; Animals; Chromatography, Affinity; Chromatography, High Pressure Liquid; Cricetinae; Cyclic AMP; Ducks; Electrophoresis, Polyacrylamide Gel; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Humans; Isoproterenol; Lung; Phosphorylation; Protein Kinases; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Turkeys; Xenopus laevis | 1985 |
Reconstitution of the regulatory functions of beta-adrenergic receptors.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Chemical Phenomena; Chemistry; Erythrocyte Membrane; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hormones; In Vitro Techniques; Isoproterenol; Kinetics; Liposomes; Models, Biological; Phospholipids; Pindolol; Propranolol; Rats; Receptors, Adrenergic, beta; Synaptic Transmission; Thermodynamics; Thionucleotides | 1984 |
Receptor-specific mechanisms of desensitization of beta-adrenergic receptor function.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Catecholamines; Cell Line; Concanavalin A; Cyclic AMP; Enzyme Activation; Erythrocytes; Guanosine Triphosphate; Isoproterenol; Kinetics; Models, Biological; Phosphorylation; Propanolamines; Rana catesbeiana; Rana pipiens; Receptors, Adrenergic, beta | 1984 |
418 other study(ies) available for isoproterenol and guanosine triphosphate
| Article | Year |
|---|---|
Desensitization of beta-adrenergic receptors by beta-adrenergic agonists in a cell-free system: resensitization by guanosine 5'-(beta, gamma-imino)triphosphate and other purine nucleotides.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Alprenolol; Animals; Cell Membrane; Cell-Free System; Dose-Response Relationship, Drug; Enzyme Activation; Erythrocytes; Guanosine Triphosphate; Isoproterenol; Kinetics; Propranolol; Purine Nucleotides; Receptors, Adrenergic; Structure-Activity Relationship | 1976 |
Adenylyl cyclase activities in ovarian tissues. I. Homogenization and conditions of assay in graafian follicles and corpora lutea of rabbits, rats, and pigs: regulation by ATP, and some comparative properties.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Corpus Luteum; Enzyme Activation; Epinephrine; Female; Guanosine Triphosphate; Hydrogen-Ion Concentration; Isoproterenol; Luteinizing Hormone; Magnesium; Ovarian Follicle; Ovary; Pregnancy; Prostaglandins E; Rabbits; Rats; Swine | 1976 |
Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Bacterial Toxins; Binding, Competitive; Cell Line; Cyclic AMP; Fluorides; Guanosine Triphosphate; Isoproterenol; Karyotyping; Lymphoma; Mice; Mutation; Prostaglandins E; Receptors, Adrenergic; Receptors, Adrenergic, beta; Vibrio cholerae | 1977 |
Neurotransmitter-sensitive adenylate cyclase in the hypothalami of guinea-pig, rat and monkey.
Topics: Adenosine; Adenylyl Cyclases; Animals; Apomorphine; Clonidine; Dopamine; Dose-Response Relationship, Drug; Guanosine Triphosphate; Guinea Pigs; Haplorhini; Hypothalamus; Isoproterenol; Macaca mulatta; Male; Median Eminence; Neurotransmitter Agents; Norepinephrine; Piribedil; Rats; Serotonin; Sodium Fluoride | 1977 |
Catecholamine and guanine nucleotide activation of skeletal muscle adenylate cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Catecholamines; Enzyme Activation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Muscles; Rabbits; Receptors, Adrenergic, beta | 1979 |
Proceedings: Regulation of adenylate cyclase activity in the 25000 X g sediment of adipose tissue from obese-hyperglycemic (ob/ob) mice from Bar Harbor.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Drug Synergism; Ethanol; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Isoproterenol; Male; Mice; Mice, Obese; Prostaglandins E | 1976 |
Reduction of GTP activation of adenylate cyclase system by its coupling to hormone receptor.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Butyrates; Cell Membrane; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; HeLa Cells; Humans; Isoproterenol; Kinetics; Receptors, Cyclic AMP | 1979 |
Hormone action at the membrane level. IV. Epinephrine binding to rat liver plasma membranes and rat epididymal fat cells.
Topics: Adipose Tissue; Animals; Binding Sites; Cell Membrane; Epididymis; Epinephrine; Guanosine Triphosphate; Isoproterenol; Kinetics; Liver; Magnesium; Male; Phenoxybenzamine; Phospholipases; Propranolol; Rats; Receptors, Cell Surface; Trypsin | 1975 |
Characteristics of 5'-guanylyl imidodiphosphate-activated adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Anura; Cell Membrane; Chloromercuribenzoates; Cyclic AMP; Dogs; Enzyme Activation; Erythrocytes; Guanosine Triphosphate; Isoproterenol; Kinetics; Myocardium; Time Factors | 1975 |
Stimulation of adenylate cyclase from isolated hepatocytes and Kupffer cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Fluorides; Glucagon; Guanosine Triphosphate; Hyaluronoglucosaminidase; In Vitro Techniques; Iron; Isoproterenol; Kupffer Cells; Liver; Male; Microbial Collagenase; Microscopy, Phase-Contrast; Peptides; Perfusion; Prostaglandins E; Rats; Secretin | 1975 |
Irreversible stimulation of adenylate cyclase activity of fat cell membranes of phosphoramidate and phosphonate analogs of GTP.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Aniline Compounds; Animals; Binding, Competitive; Cell Membrane; Diphosphates; Dithiothreitol; Edetic Acid; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Hydroxylamines; Isoproterenol; Mercury; Organometallic Compounds; Phosphates; Rats; Sodium | 1975 |
Mechanism of activation of adenylate cyclase by Vibrio cholerae enterotoxin. Relations to the mode of activation by hormones.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Anti-Bacterial Agents; Enterotoxins; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guinea Pigs; Hormones; Ileum; Intestinal Mucosa; Isoproterenol; Kinetics; Liver; Magnesium; Male; Organ Specificity; Rats; Receptors, Drug; Vibrio cholerae | 1975 |
Hormonal regulation of pancreatic islet adenyl cyclase.
Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Cell Membrane; Cholecystokinin; Fluorides; Glucagon; Growth Hormone; Guanosine Triphosphate; Insulin; Islets of Langerhans; Isoproterenol; Kinetics; Male; Phentolamine; Propranolol; Prostaglandins E; Rats; Secretin | 1976 |
Vascular adenylate cyclase: role of age and guanine nucleotide activation.
Topics: Adenosine; Adenylyl Cyclases; Aging; Animals; Aorta; Cyclic AMP; Guanine Nucleotides; Guanosine Triphosphate; Isoproterenol; Male; Mesenteric Arteries; Prostaglandins E; Rats | 1977 |
Mechanism of regulation of adenylate cyclase activity in human polymorphonuclear leukocytes by calcium, guanosyl nucleotides, and positive effectors.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Calcium; Cyclic AMP; Enzyme Activation; Guanosine Triphosphate; Histamine; Humans; Isoproterenol; Kinetics; Magnesium; Neutrophils; Prostaglandins E | 1977 |
Use of (-)-[3H]dihydroalprenolol to study beta adrenergic receptor-adenylate cyclase coupling in C6 glioma cells: role of 5'-guanylylimidodiphosphate.
Topics: Adenylyl Cyclases; Alprenolol; Binding Sites; Clone Cells; Drug Interactions; Enzyme Activation; Glioma; Guanosine Triphosphate; Isoproterenol; Kinetics; Receptors, Adrenergic; Receptors, Adrenergic, beta; Structure-Activity Relationship; Time Factors | 1977 |
Relationship between the beta-adrenergic receptor and adenylate cyclase.
Topics: Adenylyl Cyclases; Bacterial Toxins; Cell Line; Cell Membrane; Enzyme Activation; Guanosine Triphosphate; Isoproterenol; Kinetics; Ligands; Lymphoma; Mathematics; Mutation; Pindolol; Propranolol; Prostaglandins E; Receptors, Adrenergic; Receptors, Adrenergic, beta; Ribonucleotides; Vibrio cholerae | 1977 |
Control of catecholamine stimulated adenylate cyclase in pigeon erythrocyte membranes by guanylnucleotides.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Columbidae; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Guanine Nucleotides; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Receptors, Cell Surface; Tubulin | 1976 |
Activation of turkey erythrocyte adenylate cyclase and blocking of the catecholamine-stimulated GTPase by guanosine 5'-(gamma-thio) triphosphate.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Enzyme Activation; Erythrocytes; GTP Phosphohydrolases; Guanosine Triphosphate; Isoproterenol; Kinetics; Phosphoric Monoester Hydrolases; Propranolol; Turkeys | 1977 |
Reduction in beta-adrenergic response of cultured glioma cells following depletion of intracellular GTP.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Cell Line; Cell Membrane; Cyclic AMP; Enzyme Activation; Glioma; Guanosine Triphosphate; Isoproterenol; Kinetics; Mycophenolic Acid; Time Factors | 1977 |
Reconstitution of catecholamine-sensitive adenylate cyclase activity: interactions of solubilized components with receptor-replete membranes.
Topics: Adenylyl Cyclases; Binding, Competitive; Catecholamines; Cell Membrane; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; L Cells; Mutation; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1977 |
Influence of cholera toxin on the regulation of adenylate cyclase by GTP.
Topics: Adenylyl Cyclases; Binding Sites; Cell Line; Cell Membrane; Cholera Toxin; Cyclic AMP; Enzyme Activation; GTP Phosphohydrolases; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Lymphoma; NAD; Phosphoric Monoester Hydrolases; Propranolol | 1977 |
Properties of beta-adrenergic receptors in untreated and butyrate-treated Hela cells.
Topics: Adenylyl Cyclases; Alprenolol; Binding Sites; Butyrates; Cyclic AMP; Epinephrine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; HeLa Cells; Isoproterenol; Norepinephrine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1978 |
Muscarinic cholinergic receptor modulation of beta-adrenergic receptor affinity for catecholamines.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Dogs; Guanosine Triphosphate; Isoproterenol; Kinetics; Methacholine Compounds; Myocardium; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Receptors, Muscarinic | 1978 |
Effects of isoprenaline on the time course of the cyclic AMP level in rat uterus.
Topics: Adenosine; Animals; Catechols; Corticosterone; Cyclic AMP; Dipyridamole; Female; Guanosine Triphosphate; Isoproterenol; Muscle Relaxation; Myometrium; Puromycin; Rats; Theophylline; Uterus | 1978 |
The agonist-specific effect of magnesium ion on binding by beta-adrenergic receptors in S49 lymphoma cells. Interaction of GTP and magnesium in adenylate cyclase activation.
Topics: Adenylyl Cyclases; Cell Line; Cell Membrane; Enzyme Activation; Fluorides; Guanosine Triphosphate; Isoproterenol; Kinetics; Lymphoma; Magnesium; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1978 |
Evidence in intact cells for an involvement of GTP in the activation of adenylate cyclase.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Cell Line; Cholera Toxin; Cyclic AMP; Enzyme Activation; Guanosine Triphosphate; Isoproterenol; Kinetics; Mycophenolic Acid; Prostaglandins E; Ribavirin | 1979 |
S49 lymphoma wild type and variant clones contain normal calcium dependent regulator.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Calcium; Calmodulin; Carrier Proteins; Cell Line; Clone Cells; Enzyme Activation; Fluorides; Guanosine Triphosphate; Isoproterenol; Lymphoma; Neoplasms, Experimental | 1978 |
Effects of cholera toxin and guanosine 5'-[betagamma-imido]triphosphate on beta-adrenergic-receptor affinity.
Topics: Alprenolol; Animals; Anura; Cholera Toxin; Erythrocyte Membrane; Erythrocytes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1978 |
Isoproterenol-induced desensitization of adenylate cyclase responsiveness in a cell-free system.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cyclic AMP; Fluorides; Guanosine Triphosphate; Isoproterenol; Kidney; Kinetics; Prostaglandins E; Rats | 1979 |
Catecholamine-induced desensitization involves an uncoupling of beta-adrenergic receptors and adenylate cyclase.
Topics: Adenylyl Cyclases; Astrocytoma; Benzyl Alcohols; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Guanosine Triphosphate; Isoproterenol; Membranes; Pindolol; Protein Binding; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1979 |
Multiple effects of guanosine triphosphate on beta adrenergic receptors and adenylate cyclase activity in rat heart, lung and brain.
Topics: Adenylyl Cyclases; Animals; Brain; Drug Interactions; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Lung; Male; Myocardium; Pindolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1979 |
Differential effects of GTP on the coupling of beta-adrenergic receptors to adenylate cyclase from frog and turkey erythrocytes. Application of new methods for the analysis of receptor-effector coupling.
Topics: Adenylyl Cyclases; Animals; Anura; Dihydroalprenolol; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Guanosine Triphosphate; Isoproterenol; Kinetics; Receptors, Adrenergic; Receptors, Adrenergic, beta; Turkeys | 1979 |
The fat cell adenylate cyclase system. Characterization and manipulation of its bimodal regulation by GTP.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cell Membrane; Cholera Toxin; Guanosine Triphosphate; Isoproterenol; Kinetics; Rats; Ribonucleotides | 1979 |
Adenylate cyclase assembled in vitro: cholera toxin substrates determine different patterns of regulation by isoproterenol and guanosine 5'-triphosphate.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Erythrocyte Membrane; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Lymphoma; Mice; Neoplasms, Experimental; Receptors, Adrenergic, beta; Turkeys | 1979 |
Regulation of uterine smooth muscle cell beta-adrenergic catecholamine-sensitive adenylate cyclase by Mg2+ and guanylyl nucleotide.
Topics: Adenylyl Cyclases; Animals; Enzyme Activation; Female; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Magnesium; Male; Muscle, Smooth; Myometrium; Rats; Receptors, Adrenergic, beta; Uterus | 1979 |
Enhanced GTP-dependent activities of the adenylate cyclase system: basis for increased hormonal responsiveness.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Cyclic AMP; Guanosine Triphosphate; Isoleucine; Isoproterenol; Kidney; Picolinic Acids; Prostaglandins E; Rats | 1979 |
Stimulatory and inhibitory effects of guanyl-5'-yl imidodiphosphate on adenylate cyclase activity of cardiac sarcolemma.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Egtazic Acid; Female; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Myocardium; Sarcolemma; Stimulation, Chemical | 1978 |
Unique uncoupling of the frog erythrocyte adenylate cyclase system by manganese. Loss of hormone and guanine nucleotide-sensitive enzyme activities without loss of nucleotide-sensitive, high affinity agonist binding.
Topics: Adenylyl Cyclases; Animals; Anura; Erythrocyte Membrane; Erythrocytes; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Magnesium; Manganese; Prostaglandins E | 1979 |
Enhancement of hormonal stimulation in intact cells. Potentiation of GTP-dependent activation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Enzyme Activation; Guanosine Triphosphate; Isoleucine; Isoproterenol; Kidney; Kinetics; Picolinic Acids; Prostaglandins E; Rats | 1979 |
Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Erythrocyte Membrane; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Liver; Parotid Gland; Propranolol; Rats; Thionucleotides; Turkeys | 1979 |
Effect of propylthiouracil treatment on the regulation of adenylate cyclase activity in rat myocardium.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; Isoproterenol; Male; Myocardium; Propylthiouracil; Rats | 1979 |
Reconstitution of catecholamine-sensitive adenylate cyclase activity: interaction of components following cell-cell and membrane-cell fusion.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Cell Fusion; Cell Line; Cell Membrane; Cells, Cultured; Enzyme Activation; Guanosine Triphosphate; Isoproterenol; Mice; Propranolol; Prostaglandins E | 1977 |
5'-Guanylylimidodiphosphate-activated adenylate cyclase of cardiac sarcolemma displays higher affinity for magnesium ions.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Enzyme Activation; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; In Vitro Techniques; Isoproterenol; Magnesium; Manganese; Muscle Proteins; Myocardium; Phospholipases; Sarcolemma; Temperature; Trypsin | 1977 |
5' Guanylyl-imidodiphosphate actions on adenylate cyclase in homogenates of rat cerebral cortex plus neuronal and capillary fractions.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Capillaries; Cerebral Cortex; Dopamine; Enzyme Activation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Neurons; Norepinephrine; Rats | 1978 |
5'-guanylimidodiphosphate stimulation of slow Ca2+ current in myocardial cells.
Topics: Action Potentials; Animals; Calcium; Chick Embryo; Dose-Response Relationship, Drug; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Ion Channels; Isoproterenol; Manganese; Myocardium; Propranolol; Tetrodotoxin; Verapamil | 1978 |
Mechanism of action of Vibrio cholerae enterotoxin. Effects on adenylate cyclase of toad and rat erythrocyte plasma membranes.
Topics: Adenylyl Cyclases; Animals; Bufo marinus; Cell Membrane; Enterotoxins; Enzyme Activation; Epinephrine; Erythrocytes; Fluorides; Guanosine Triphosphate; Humans; Isoproterenol; Kinetics; Magnesium; Protein Binding; Rats; Vibrio cholerae | 1975 |
Holocatalytic state of adenylate cyclase in turkey erythrocyte membranes: formation with guanylylimidodiphosphate plus isoproterenol without effect on affinity of beta-receptor.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Edetic Acid; Erythrocytes; Guanosine Triphosphate; Isoproterenol; Mathematics; Protein Binding; Receptors, Adrenergic; Turkeys | 1976 |
Irreversible activation of adenylate cyclase of toad erythrocyte plasma membrane by 5'-guanylylimidodiphosphate.
Topics: Adenylyl Cyclases; Animals; Bufo marinus; Cell Membrane; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Erythrocytes; Guanosine Triphosphate; Isoproterenol; Kinetics; Temperature | 1976 |
Catecholamine-sensitive adenylate cyclase in frontal cortex of primate brain.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Calcium; Catecholamines; Cerebral Cortex; Clozapine; Dopamine; Drug Combinations; Fluphenazine; Frontal Lobe; Guanosine Triphosphate; Haloperidol; Haplorhini; Isoproterenol; Macaca mulatta; Norepinephrine; Phentolamine; Receptors, Adrenergic; Receptors, Dopamine; Sodium Fluoride; Time Factors | 1976 |
Catecholamine-induced release of [3H]-Gpp(NH)p from turkey erythrocyte adenylate cyclase.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Allosteric Site; Animals; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Guanine Nucleotides; Guanosine Triphosphate; Isoproterenol; Kinetics; Propranolol; Turkeys | 1977 |
GTP-binding proteins in membranes and the control of adenylate cyclase activity.
Topics: Adenylyl Cyclases; Affinity Labels; Animals; Azides; Carrier Proteins; Columbidae; Erythrocyte Membrane; Erythrocytes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol | 1977 |
Activation of adenylate cyclase by guanosine 5' alpha, beta methylene triphosphate.
Topics: Adenylyl Cyclases; Animals; Columbidae; Dose-Response Relationship, Drug; Enzyme Activation; Erythrocyte Membrane; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol | 1977 |
Regulation of beta-adrenergic receptors by guanyl-5'-yl imidodiphosphate and other purine nucleotides.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Binding, Competitive; Blood Proteins; Cell Membrane; Erythrocytes; Guanine Nucleotides; Guanosine Triphosphate; Isoproterenol; Kinetics; Protein Binding; Purine Nucleotides; Receptors, Adrenergic | 1976 |
Synergistic activation of adenylate cyclase by guanylyl imidophosphate and epinephrine.
Topics: Adenylyl Cyclases; Allosteric Regulation; Allosteric Site; Animals; Binding Sites; Calcium; Cell Membrane; Drug Synergism; Enzyme Activation; Epinephrine; Erythrocytes; Guanosine Triphosphate; Isoproterenol; Kinetics; Magnesium; Propranolol; Protein Binding; Turkeys | 1976 |
Effects of prostaglandins and catecholamines on rat spleen adenylate cyclase in vitro.
Topics: Adenylyl Cyclases; Enzyme Activation; Fluorides; Guanosine Triphosphate; Isoproterenol; Kinetics; Prostaglandins E; Prostaglandins F; Spleen | 1976 |
Activation of adenylate cyclase by phosphoramidate and phosphonate analogs of GTP: possible role of covalent enzyme-substrate intermediates in the mechanism of hormonal activation.
Topics: Adenylyl Cyclases; Adipose Tissue; Amides; Animals; Chromatography, Affinity; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Isoproterenol; Kinetics; Male; Organophosphonates; Rats | 1975 |
Fatty acids as modulators of membrane functions: catecholamine-activated adenylate cyclase of the turkey erythrocyte.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Drug Synergism; Enzyme Activation; Erythrocytes; Fatty Acids; Guanosine Triphosphate; Isoproterenol; Structure-Activity Relationship; Temperature; Time Factors | 1975 |
Activation of pigeon erythrocyte membrane adenylate cyclase by guanylnucleotide analogues and separation of a nucleotide binding protein.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Chromatography, Affinity; Columbidae; Enzyme Activation; Erythrocytes; Guanosine Triphosphate; Isoproterenol; Kinetics; Macromolecular Substances; Molecular Weight; Protein Binding; Ribonucleotides; Structure-Activity Relationship; Time Factors | 1975 |
Brain and caudate nucleus adenylate cyclase: effects of dopamine, GTP, E prostaglandins and morphine.
Topics: Adenylyl Cyclases; Animals; Brain; Caudate Nucleus; Cell Membrane; Dopamine; Enzyme Activation; Guanosine Triphosphate; Isoproterenol; Liver; Morphine; Prostaglandins; Rats | 1975 |
Catecholamine stimulated myocardial adenylate cyclase: effects of nucleotides.
Topics: Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cell Membrane; Deoxyribonucleotides; Dogs; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Heart; Inosine Nucleotides; Isoproterenol; Kinetics; Myocardium; Propranolol; Ribonucleotides; Time Factors | 1975 |
Effects of atrionatriuretic factor on Ca2+ current and Cai-independent transient outward K+ current in human atrial cells.
Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Calcium; Calcium Channels; Dialysis; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heart Atria; Humans; In Vitro Techniques; Isoproterenol; Membrane Potentials; Middle Aged; Myocardium; Potassium Channels | 1992 |
Phosphorylation-independent regulation of cardiac IK by guanine nucleotides and isoproterenol.
Topics: Animals; Cyclic AMP; Electrophysiology; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Myocardium; Phosphorylation; Potassium Channels; Thionucleotides | 1992 |
Beta-adrenergic-receptor-mediated dissociation and membrane release of the Gs protein in S49 lymphoma-cell membranes. Dependence on Mg2+ and GTP.
Topics: Animals; Cell Line; Cell Membrane; Enzyme-Linked Immunosorbent Assay; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Kinetics; Lymphoma; Macromolecular Substances; Magnesium; Mice; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1992 |
Ca2+ potentiates corticotropin-induced, but not isoproterenol-induced, [3H]guanosine diphosphate release in rat adipocyte membranes.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Calcium; Cell Membrane; Drug Synergism; Egtazic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Rats; Tritium | 1992 |
The effect of in vitro aging on human lung fibroblast beta-adrenergic receptor density, coupling and response.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Cell Line; Cellular Senescence; Fibroblasts; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Lung; Pindolol; Receptors, Adrenergic, beta | 1992 |
Guanine nucleotides regulate beta-adrenergic activation of Na-H exchange independently of receptor coupling to Gs.
Topics: Amiloride; Animals; Carrier Proteins; Cells, Cultured; Cricetinae; Dogs; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen-Ion Concentration; Ileum; Intestinal Mucosa; Isoproterenol; Kinetics; L Cells; Meglumine; Mice; Propranolol; Receptors, Adrenergic, beta; Sodium; Sodium Fluoride; Sodium-Hydrogen Exchangers; Thionucleotides; Transfection | 1992 |
Beta-adrenergic stimulation of C6 glioma cells: effects of cAMP overproduction on cellular metabolites. A multinuclear NMR study.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Cyclic AMP; Glioma; Glucose; Glutamates; Glutamine; Guanosine Triphosphate; Isoproterenol; Kinetics; Lactates; Magnetic Resonance Spectroscopy; Phosphorus; Phosphorylation; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1992 |
Pre-steady state study of beta-adrenergic and purinergic receptor interaction in C6 cell membranes: undelayed balance between positive and negative coupling to adenylyl cyclase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Membrane; Cyclic AMP; Enzyme Activation; Glioma; Guanosine Triphosphate; Isoproterenol; Kinetics; Pertussis Toxin; Receptors, Adrenergic, beta; Receptors, Purinergic; Thionucleotides; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Beta 1- and beta 2-adrenergic receptors display subtype-selective coupling to Gs.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cell Line; GTP-Binding Proteins; Guanosine Triphosphate; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Kinetics; Mice; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; Transfection | 1992 |
The ATP-induced inward current in mouse lacrimal acinar cells is potentiated by isoprenaline and GTP.
Topics: Adenosine Triphosphate; Animals; Calcium; Cyclic AMP; Drug Synergism; Evoked Potentials; Guanosine Triphosphate; Ion Channels; Ion Pumps; Isoproterenol; Lacrimal Apparatus; Membrane Potentials; Mice; Receptors, Adrenergic | 1992 |
Stimulatory and inhibitory regulation of calcium-activated potassium channels by guanine nucleotide-binding proteins.
Topics: Adenylate Cyclase Toxin; Animals; Calcium; Cells, Cultured; Dogs; Ferrets; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Membrane Potentials; Muscle, Smooth; Pertussis Toxin; Potassium Channels; Swine; Thionucleotides; Trachea; Virulence Factors, Bordetella | 1992 |
Studies on the interaction of alpha subunits of GTP-binding proteins with beta gamma dimers.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Baculoviridae; Brain Chemistry; Cattle; Cell Line; DNA; Erythrocytes; Gene Expression; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Isoproterenol; Macromolecular Substances; Moths; Placenta; Recombinant Proteins; Rod Cell Outer Segment | 1992 |
Effects of adenosine analogues on ADP ribosylation of GS protein in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate Ribose; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Cattle; Cell Membrane; Cholera Toxin; Coronary Vessels; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Kinetics; Membrane Proteins; Muscle, Smooth, Vascular; Receptors, Purinergic | 1992 |
Endothelin activates voltage-dependent Ca2+ current by a G protein-dependent mechanism in rabbit cardiac myocytes.
Topics: Acetylcholine; Animals; Calcium; Endothelins; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardium; Pertussis Toxin; Rabbits; Thionucleotides; Time Factors; Virulence Factors, Bordetella | 1992 |
Reduced adenylyl cyclase inhibition by carbachol and GTP during acute myocardial ischaemia.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Colforsin; Coronary Disease; Dogs; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Receptors, Muscarinic | 1992 |
Characterization of high affinity GTPase activity correlated to beta-adrenergic receptor stimulation of adenylyl cyclase in rat parotid membranes.
Topics: Adenylyl Cyclases; Animals; Autoradiography; Cell Membrane; Cholera Toxin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; GTP Phosphohydrolases; Guanosine Triphosphate; Isoproterenol; Male; Parotid Gland; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Signal Transduction | 1991 |
Progesterone promotes the coupling of beta-adrenoceptors to G-proteins in rat myometrium.
Topics: Animals; Binding, Competitive; Cell Membrane; Estradiol; Female; GTP-Binding Proteins; Guanosine Triphosphate; Iodocyanopindolol; Isoproterenol; Kinetics; Myometrium; Ovariectomy; Pindolol; Progesterone; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1991 |
A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors.
Topics: Adenylyl Cyclases; Animals; Asparagine; Binding Sites; Blotting, Northern; Cyclic AMP; Enzyme Activation; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Magnesium; Mice; Mutation; Oncogene Protein p21(ras); Serine; Tumor Cells, Cultured | 1991 |
Identification of a Gs activator region of the beta 2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylation.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cells, Cultured; Cricetinae; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; In Vitro Techniques; Isoproterenol; Molecular Sequence Data; Peptides; Phosphorylation; Protein Kinases; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1991 |
Caffeine-induced block of Na+ current in guinea pig single ventricular cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Caffeine; Calcium; Electric Conductivity; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Heart; Heart Ventricles; Isoproterenol; Isoquinolines; Kinetics; Membrane Potentials; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Sarcoplasmic Reticulum; Signal Transduction; Sodium; Sodium Channels; Ventricular Function | 1991 |
Epidermal growth factor activation of rat parotid gland adenylate cyclase and mediation by a GTP-binding regulatory protein.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; Female; Galactosyltransferases; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Parotid Gland; Rats; Rats, Inbred Strains; Signal Transduction | 1991 |
GTP-related difference in cyclic AMP production between resident and inflammatory human peritoneal macrophages.
Topics: Adenylyl Cyclases; Cell Separation; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dinoprostone; Epoprostenol; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Isoproterenol; Macrophages; Peritoneal Cavity; Sodium Fluoride | 1991 |
Inhibition of adenylate cyclase of catfish and rat hepatocyte membranes by 9-(tetrahydro-2-furyl)adenine (SQ 22536).
Topics: Adenine; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Cells, Cultured; Epinephrine; Female; Glucagon; Guanosine Triphosphate; Ictaluridae; Isoproterenol; Kinetics; Liver; Male; Norepinephrine; Phenylephrine; Rats; Sodium Fluoride; Species Specificity | 1991 |
In vivo adaptive control of beta-receptors and adenylate cyclase during short-term heat exposure in rat parotid glands.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Animals; Chlorides; Colforsin; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hot Temperature; Isoproterenol; Male; Manganese; Manganese Compounds; Membranes; Norepinephrine; Parotid Gland; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Synaptic Transmission; Time Factors | 1991 |
Beta-adrenergic receptor activity of cerebral microvessels is reduced in aged rats.
Topics: Adenylyl Cyclases; Aging; Alkaline Phosphatase; Animals; Brain; Cerebrovascular Circulation; gamma-Glutamyltransferase; Guanosine Triphosphate; Iodocyanopindolol; Isoproterenol; Kinetics; Male; Microcirculation; Pindolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Regression Analysis; Sodium Fluoride | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodilator Agents; Ethanolamines; Formoterol Fumarate; Guanosine Triphosphate; Guinea Pigs; Heart Ventricles; Histamine; Hydroxyquinolines; In Vitro Techniques; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Kinetics; Lung; Male; Membranes; Muscle Contraction; Muscle Relaxation; Pindolol; Procaterol; Quinolones; Radioligand Assay; Receptors, Adrenergic, beta; Trachea | 1991 |
A pertussis toxin-sensitive G-protein mediates some aspects of insulin action in BC3H-1 murine myocytes.
Topics: Animals; Cell Line; Cell Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Insulin; Isoproterenol; Kinetics; Macromolecular Substances; Mice; Muscles; Pertussis Toxin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptor, Insulin; Signal Transduction; Tyrosine; Virulence Factors, Bordetella | 1990 |
Ontogeny of the adenylate cyclase system in the pulmonary vascular smooth muscle of the fetal lamb.
Topics: Adenylyl Cyclases; Aging; Animals; Cell Membrane; Colforsin; Cyclic AMP; Embryonic and Fetal Development; Female; Fetus; Guanosine Triphosphate; Isoproterenol; Muscle Development; Muscle, Smooth, Vascular; Pregnancy; Pulmonary Circulation; Receptors, Adrenergic, beta; Sheep; Sodium Fluoride; Stimulation, Chemical | 1991 |
The beta-adrenergic receptor-regulated 1,4-dihydropyridine calcium channel receptor sites in coronary artery smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channels; Cell Membrane; Cyclic AMP; Dihydropyridines; Dogs; Guanosine Triphosphate; Isoproterenol; Isradipine; Male; Microsomes; Muscle, Smooth, Vascular; Receptors, Adrenergic, beta | 1991 |
Magnesium reversal of lithium inhibition of beta-adrenergic and muscarinic receptor coupling to G proteins.
Topics: Animals; Carbachol; Cerebral Cortex; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Lithium; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Muscarinic | 1991 |
Influence of streptozotocin-induced diabetes on adenylate cyclase activity in cultured type II pneumocytes.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Deoxyglucose; Diabetes Mellitus, Experimental; Guanosine Triphosphate; Insulin; Isoproterenol; Lung; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Receptor, Insulin; Sodium Fluoride; Streptozocin | 1991 |
Interaction between alpha 2- and beta-adrenergic receptors in rat cerebral cortical membranes: clonidine-induced reduction in agonist and antagonist affinity for beta-adrenergic receptors.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Clonidine; Dihydroalprenolol; Guanosine Triphosphate; Isoproterenol; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sympathomimetics; Yohimbine | 1991 |
Prostacyclin production and mediation of adenylate cyclase activity in the pulmonary artery. Alterations after prolonged hypoxia in the rat.
Topics: Adenylyl Cyclases; Animals; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Guanosine Triphosphate; Hypertension, Pulmonary; Hypoxia; Indomethacin; Isoproterenol; Male; Pulmonary Artery; Rats; Rats, Inbred Strains | 1991 |
Alterations in G-protein expression and the hormonal regulation of adenylate cyclase in the adipocytes of obese (fa/fa) Zucker rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Macromolecular Substances; Male; Obesity; Rats; Rats, Zucker; Secretin; Thyrotropin | 1991 |
Determination of G-protein levels, ADP-ribosylation by cholera and pertussis toxins and the regulation of adenylyl cyclase activity in liver plasma membranes from lean and genetically diabetic (db/db) mice.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Mice; Mice, Inbred C57BL; Pertussis Toxin; Virulence Factors, Bordetella | 1991 |
Synergistic activation of brain adenylate cyclase by calmodulin, and either GTP or catecholamines including dopamine.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Calmodulin; Catecholamines; Cerebral Cortex; Colforsin; Corpus Striatum; Dopamine; Drug Synergism; Egtazic Acid; Enzyme Activation; Guanosine Triphosphate; Intracellular Membranes; Isoproterenol; Kinetics; Rats; Synaptosomes | 1990 |
Winner of the 1988 NAASO Young Investigator Award. Regulation of fat cell adenylate cyclase in young Zucker (fa/fa) rats: alterations in GTP sensitivity of adenosine A1 mediated inhibition.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Awards and Prizes; Cell Membrane; Cyclic AMP; Dietetics; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Lipolysis; Obesity; Phenylisopropyladenosine; Rats; Rats, Zucker; Receptors, Purinergic; Societies, Medical; United States | 1990 |
A truncation mutation in the avian beta-adrenergic receptor causes agonist-induced internalization and GTP-sensitive agonist binding characteristic of mammalian receptors.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino Acid Sequence; Animals; Base Sequence; Endocytosis; Guanosine Triphosphate; Humans; Iodocyanopindolol; Isoproterenol; Kinetics; L Cells; Ligands; Mice; Molecular Sequence Data; Mutation; Pindolol; Receptors, Adrenergic, beta; Recombinant Proteins; Transfection; Turkeys | 1990 |
Biochemical characterization of three stimulatory GTP-binding proteins. The large and small forms of Gs and the olfactory-specific G-protein, Golf.
Topics: Adenylyl Cyclases; Aluminum; Aluminum Compounds; Animals; Cell Line; Cell Membrane; Central Nervous System; Cholera Toxin; DNA; Enzyme Activation; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Kinetics; Ligands; Macromolecular Substances; Molecular Weight; Olfactory Pathways; Rats; Signal Transduction | 1990 |
Effects of treatment with a lithium-imipramine combination on components of adenylate cyclase in the cerebral cortex of the rat.
Topics: Adenylyl Cyclases; Animals; Calcium; Cerebral Cortex; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Imipramine; Isoproterenol; Lithium; Male; Nerve Tissue Proteins; Rats; Rats, Inbred Strains | 1990 |
Carbamylcholine inhibits beta-adrenergic receptor-coupled Gs protein function proximal to adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Binding Sites; Carbachol; Cell Membrane; Cholera Toxin; GTP-Binding Proteins; Guanosine Triphosphate; Heart; Isoproterenol; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Muscarinic | 1990 |
Comparison of beta adrenergic receptor binding characteristics and coupling to adenylate cyclase in rat pulmonary artery versus aorta.
Topics: Adenylyl Cyclases; Animals; Aorta; Binding Sites; Guanosine Triphosphate; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Male; Pindolol; Pulmonary Artery; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1990 |
Endurance training, not acute exercise, differentially alters beta-receptors and cyclase in skeletal fiber types.
Topics: Adenylyl Cyclases; Animals; Colforsin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Muscles; Organ Specificity; Physical Conditioning, Animal; Physical Exertion; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Reference Values; Sodium Fluoride; Succinate Cytochrome c Oxidoreductase | 1990 |
Effects of kinins on cultured arterial smooth muscle.
Topics: 6-Ketoprostaglandin F1 alpha; Actins; Animals; Bradykinin; Calcium; Calcium Channel Blockers; Cells, Cultured; Cyclic AMP; Dinoprostone; Fluorescent Antibody Technique; Gallic Acid; Guanosine Triphosphate; Indomethacin; Isoproterenol; Kinetics; Mesenteric Arteries; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1990 |
Diabetes abolishes the GTP-dependent, but not the receptor-dependent inhibitory function of the inhibitory guanine-nucleotide-binding regulatory protein (Gi) on adipocyte adenylate cyclase activity.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Blotting, Western; Cell Membrane; Colforsin; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Niacin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Purinergic | 1990 |
Chronic isoproterenol administration causes altered beta adrenoceptor-Gs-coupling in guinea pig lung.
Topics: Animals; Binding, Competitive; Dihydroalprenolol; Guanosine Triphosphate; Guinea Pigs; Isoproterenol; Lung; Male; Muscle Relaxation; Receptors, Adrenergic, beta | 1990 |
Inhibition of cardiac Na+ currents by isoproterenol.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Magnesium; Myocardium; Sodium Channels; Thionucleotides | 1990 |
Epidermal growth factor desensitizes the gonadotropin-responsive adenylyl cyclase in membranes isolated from MA-10 Leydig tumor cells and luteinized rat ovaries.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Cell-Free System; Chorionic Gonadotropin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; Female; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Leydig Cell Tumor; Ovary; Rats; Sodium Fluoride; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1990 |
Demonstration of high- and low-affinity beta-adrenergic receptors in slide-mounted sections of rat and human brain.
Topics: Animals; Binding, Competitive; Brain; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Pindolol; Rats; Receptors, Adrenergic, beta | 1990 |
Whole-cell calcium current in guinea-pig ventricular myocytes dialysed with guanine nucleotides.
Topics: Action Potentials; Adenylyl Cyclases; Animals; Calcium; Calcium Channels; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Guinea Pigs; Heart Ventricles; Ion Channel Gating; Isoproterenol; Myocardium; Phosphorylation; Signal Transduction | 1990 |
Mechanisms underlying the stimulation of PTH release by GppNHp in permeabilized bovine parathyroid cells.
Topics: Animals; Cattle; Cyclic AMP; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Inositol Phosphates; Isoproterenol; Parathyroid Glands; Parathyroid Hormone; Permeability | 1990 |
GTP-dependent regulation of myometrial KCa channels incorporated into lipid bilayers.
Topics: Adenosine Triphosphate; Animals; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Lipid Bilayers; Magnesium; Myometrium; Norepinephrine; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sympathomimetics; Thionucleotides | 1990 |
Carbamazepine and electroconvulsive shock attenuate beta-adrenoceptor and muscarinic cholinoceptor coupling to G proteins in rat cortex.
Topics: Animals; Carbamazepine; Cerebral Cortex; Drug Administration Schedule; Electroshock; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Muscarinic; Tritium | 1990 |
[Role of G protein-mediated signal transduction in molecular pharmacodynamics].
Topics: Adenylyl Cyclases; Animals; beta-Adrenergic Receptor Kinases; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Isoproterenol; Pharmacokinetics; Pindolol; Propranolol; Protein Binding; Protein Kinases; Rats; Receptors, Adrenergic, beta; Receptors, Cell Surface; Second Messenger Systems; Signal Transduction | 1990 |
Nonreceptor-mediated responses of adenylate cyclase in membranes from liver, muscle, and white and brown adipose tissue of obese (fa/fa) and lean (Fa/) Zucker rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Adipose Tissue, Brown; Animals; Body Weight; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Liver; Muscles; Norepinephrine; Obesity; Organ Size; Rats; Rats, Zucker; Receptors, Adrenergic, beta | 1990 |
Comparison of the luteinizing hormone-sensitive adenylyl cyclase of the pig ovarian follicle and corpus luteum and its susceptibility to in vitro hormone-dependent desensitization.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Chorionic Gonadotropin; Corpus Luteum; Dose-Response Relationship, Drug; Drug Tolerance; Female; Guanosine Triphosphate; Isoproterenol; Luteinizing Hormone; Ovarian Follicle; Swine; Urea | 1990 |
Adenylate cyclase activities of vascular smooth muscle in early and established DOCA/salt hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Calmodulin; Colforsin; Desoxycorticosterone; Guanosine Triphosphate; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic | 1990 |
Differential desensitization of A1 adenosine receptor-mediated inhibition of cardiac myocyte contractility and adenylate cyclase activity. Relation to the regulation of receptor affinity and density.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Chick Embryo; Guanosine Triphosphate; Heart; Isoproterenol; Kinetics; Myocardial Contraction; Myocardium; Phenylisopropyladenosine; Radioligand Assay; Receptors, Purinergic | 1990 |
Factors essential for desensitization of pigeon erythrocyte adenylate cyclase responsiveness in a cell-free system.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Binding, Competitive; Cell-Free System; Columbidae; Cyclic AMP; Cytosol; Drug Tolerance; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Protein Kinases; Thionucleotides | 1985 |
Phosphorylation of the beta-adrenergic receptor in intact cells: relationship to heterologous and homologous mechanisms of adenylate cyclase desensitization.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adaptation, Physiological; Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Phosphorylation; Rana pipiens; Receptors, Adrenergic, beta; Sodium Fluoride | 1987 |
A G protein directly regulates mammalian cardiac calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; Ion Channels; Isoproterenol; Leupeptins; Membrane Potentials; Phosphorylation; Thionucleotides; Ventricular Function | 1987 |
Alterations in hormone-sensitive adenylate cyclase of cloned rat osteosarcoma cells during long-term culture.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bone Neoplasms; Calcitonin; Dinoprostone; Fluorides; Guanosine Triphosphate; Hormones; Isoproterenol; Osteosarcoma; Parathyroid Hormone; Rats; Tumor Cells, Cultured | 1986 |
Role of adenosine 3',5'-monophosphate and the Ri-receptor Gi-coupled adenylate cyclase inhibitory pathway in the mechanism whereby adrenalectomy increases the adenosine antilipolytic effect in rat fat cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Adrenalectomy; Animals; Bucladesine; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Lipolysis; Male; Manganese; Niacin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Thionucleotides | 1989 |
Role of the calcium-calmodulin system in the adenylate cyclase activity of vascular smooth muscle.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Calcimycin; Calcium; Calmodulin; Colforsin; Edetic Acid; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Trifluoperazine | 1989 |
Reconstitution of cyc- S49 membranes by in vitro translated Gs alpha. Membrane anchorage and functional implications.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Isoproterenol; Lymphoma; Mice; Molecular Weight; Mutation; NAD; Osmolar Concentration; Protein Biosynthesis; RNA, Messenger; Thionucleotides; Tumor Cells, Cultured | 1989 |
G regulatory proteins and muscarinic receptor signal transduction in mucous acini of rat submandibular gland.
Topics: Adenylate Cyclase Toxin; Animals; Calcium; Carbachol; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoproterenol; Kinetics; Mucous Membrane; Pertussis Toxin; Phosphatidylinositols; Rats; Receptors, Muscarinic; Signal Transduction; Submandibular Gland; Thionucleotides; Virulence Factors, Bordetella | 1989 |
Monovalent ion enhancement of beta-adrenergic-stimulated adenylate cyclase activity in mouse parotid gland.
Topics: Adenylyl Cyclases; Animals; Brain; Chlorides; Colforsin; Drug Synergism; Enzyme Activation; Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Lithium; Lithium Chloride; Liver; Mice; Parotid Gland; Sodium; Thionucleotides | 1989 |
Comparison of two putatively selective radioligands for labeling central nervous system beta-adrenergic receptors: inadequacy of [3H]dihydroalprenolol.
Topics: Alprenolol; Animals; Brain Chemistry; Dihydroalprenolol; Guanosine Triphosphate; Isoproterenol; Kinetics; Male; Propanolamines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Serotonin | 1989 |
Beta-adrenergic inhibition of cardiac sodium channels by dual G-protein pathways.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heart; Isoproterenol; Potassium Channels; Rats; Receptors, Adrenergic, beta; Signal Transduction; Sodium Channels; Thionucleotides | 1989 |
New form of pseudohypoparathyroidism with abnormal catalytic adenylate cyclase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adult; Cell Line; Cell Membrane; Cyclic AMP; Fibroblasts; Glutamine; Guanosine Triphosphate; Humans; Isoproterenol; Pseudohypoparathyroidism; Reference Values; Skin | 1989 |
Mutations in the GTP-binding site of GS alpha alter stimulation of adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Base Sequence; Cell Line; Cyclic AMP; DNA; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Kinetics; Membrane Proteins; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras) | 1989 |
Mapping of beta-adrenoceptor coupling domains to Gs-protein by site-specific synthetic peptides.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Enzyme Activation; Erythrocyte Membrane; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Molecular Structure; Peptide Mapping; Peptides; Propranolol; Receptors, Adrenergic, beta; Turkeys | 1989 |
Autonomic receptor interactions in isolated cardiac myocytes from hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Blood Pressure; Carbachol; Guanosine Triphosphate; Hypertension; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Kinetics; Male; Myocardium; Pindolol; Quinuclidinyl Benzilate; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Receptors, Cholinergic | 1989 |
Neomycin induces high-affinity agonist binding of G-protein-coupled receptors.
Topics: Binding Sites; Cell Line; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Isoproterenol; Leukemia; Magnesium; Neomycin; Oligopeptides; Pertussis Toxin; Receptors, Adrenergic, beta; Receptors, Formyl Peptide; Receptors, Immunologic; Signal Transduction; Virulence Factors, Bordetella | 1989 |
Chronic norepinephrine elicits desensitization by uncoupling the beta-receptor.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dogs; Drug Tolerance; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart Ventricles; Hemodynamics; Isoproterenol; Norepinephrine; Organ Size; Pindolol; Receptors, Adrenergic, beta; Sodium Fluoride; Sodium-Potassium-Exchanging ATPase; Ventricular Function | 1989 |
Skeletal muscle beta-receptors and isoproterenol-stimulated vasodilation in canine heart failure.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cardiac Output, Low; Data Interpretation, Statistical; Dogs; Guanosine Triphosphate; Hemodynamics; Hindlimb; Iodine Radioisotopes; Isoproterenol; Muscles; Receptors, Adrenergic, beta; Vasodilation | 1989 |
Mechanisms of beta-adrenoceptor mediated increase in delayed rectifier potassium current.
Topics: Animals; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Membrane Potentials; Potassium; Receptors, Adrenergic, beta; Second Messenger Systems; Thionucleotides; Ventricular Function | 1989 |
The beta-adrenoceptor is precoupled to Gs in chicken erythrocyte membranes.
Topics: Adenylyl Cyclases; Animals; Chickens; Erythrocyte Membrane; Filipin; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Lidocaine; Propranolol; Receptors, Adrenergic, beta | 1989 |
Adenylate cyclase activity in homogenates of human melanoma cells. Effect of alpha-MSH and isoprenaline.
Topics: Adenylyl Cyclases; Cells, Cultured; Cyclic AMP; Guanosine Triphosphate; Humans; Isoproterenol; Melanocyte-Stimulating Hormones; Melanoma | 1989 |
Effects of GTP on hormone-stimulated adenylate cyclase activity in cerebral cortex, striatum, and hippocampus from rats treated chronically with lithium.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cerebral Cortex; Chlorides; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Guanosine Triphosphate; Hippocampus; Isoproterenol; Lithium; Lithium Chloride; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serotonin; Synaptic Membranes | 1989 |
Signal transduction by membrane receptors in viable electropermeabilized cells: isoproterenol-stimulated cyclic AMP synthesis in C6 glioma cells.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Cell Line; Cell Membrane; Cell Membrane Permeability; Cell Nucleus; Cyclic AMP; Electric Stimulation; Glioma; Guanosine Triphosphate; Isoproterenol; Kinetics; Propanolamines; Receptors, Adrenergic, beta; Signal Transduction | 1989 |
Treatment of oophorectomized guinea pigs with intrauterine 17 beta-estradiol pellets may modulate myometrial beta-adrenergic receptor binding properties.
Topics: Adrenergic beta-Antagonists; Animals; Estradiol; Female; Guanosine Triphosphate; Guinea Pigs; Isoproterenol; Myometrium; Ovariectomy; Pindolol; Progesterone; Receptors, Adrenergic, beta | 1989 |
Pregnancy-induced changes in the interaction of guinea pig myometrial beta-adrenergic receptors with l-isoproterenol.
Topics: Adrenergic beta-Antagonists; Animals; Female; Guanosine Triphosphate; Guinea Pigs; Isoproterenol; Myometrium; Pindolol; Pregnancy; Pregnancy, Animal; Receptors, Adrenergic, beta | 1989 |
Dopamine stimulated increase of GTP levels in the rat retina.
Topics: Animals; Apomorphine; Bromocriptine; Butaclamol; Dopamine; Dose-Response Relationship, Drug; Female; Guanosine Triphosphate; Isomerism; Isoproterenol; Rats; Rats, Inbred Strains; Retina | 1985 |
Adenosine inhibition of catecholamine-stimulated cardiac membrane adenylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenylyl Cyclase Inhibitors; Animals; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Male; Myocardium; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Sodium Fluoride | 1985 |
The response to isoproterenol-stimulated adenylate cyclase activity after administration of L-triiodothyronine is reduced in aged rats.
Topics: Adenylyl Cyclases; Aging; Animals; Drug Interactions; Guanosine Triphosphate; Heart; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred F344; Triiodothyronine | 1989 |
Regulation of adenylate cyclase activity and stimulation response in relation to endometrial receptivity in the rabbit.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Dinoprostone; Endometrium; Female; Guanosine Triphosphate; Isoproterenol; Pseudopregnancy; Rabbits | 1989 |
Beta-adrenergic regulation of contractility and protein phosphorylation in spontaneously beating isolated rat myocardial cells.
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Calcium; Cyclic AMP; Guanosine Triphosphate; Heart; Heart Ventricles; In Vitro Techniques; Isoproterenol; Kinetics; Male; Myocardial Contraction; Phosphoproteins; Phosphorylation; Propranolol; Proteins; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Ventricular Function | 1987 |
Sex steroid regulation of beta-adrenergic sensitive adenylate cyclase in rabbit myometrial cells in primary culture.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Female; Gonadal Steroid Hormones; Guanosine Triphosphate; Isoproterenol; Myometrium; Rabbits; Receptors, Adrenergic, beta; Uterine Contraction | 1988 |
Direct interaction between membrane-associated nucleoside diphosphate kinase and GTP-binding protein(Gs), and its regulation by hormones and guanine nucleotides.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Glucagon; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Immunoassay; Isoproterenol; Liver; Nucleoside-Diphosphate Kinase; Phosphotransferases; Rats | 1988 |
Activation of adenylate cyclase in rat fat cells promotes an increase in GTP content which controls the enzyme activity.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Cyclic AMP; Enzyme Activation; Guanosine Triphosphate; Isoproterenol; Kinetics; Lipolysis; Pertussis Toxin; Phenylisopropyladenosine; Rats; Ribavirin; Virulence Factors, Bordetella | 1988 |
Regulation of guinea pig myometrial beta-adrenoreceptors by guanosine triphosphate and magnesium ion.
Topics: Animals; Female; Guanosine Triphosphate; Guinea Pigs; Iodine Radioisotopes; Isoproterenol; Magnesium; Myometrium; Pindolol; Pregnancy; Propranolol; Radioimmunoassay; Receptors, Adrenergic, beta | 1988 |
Mechanisms of glucagon-induced homologous and heterologous desensitization of adenylate cyclase in membranes and whole Sertoli cells of the rat.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Drug Tolerance; Follicle Stimulating Hormone; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Pertussis Toxin; Phenylisopropyladenosine; Protein Kinases; Rats; Rats, Inbred Strains; Sertoli Cells; Sodium Fluoride; Virulence Factors, Bordetella | 1988 |
Effects of ethanol in vitro on the beta adrenergic receptor-coupled adenylate cyclase system.
Topics: Adenylyl Cyclases; Animals; Cell Line; Dose-Response Relationship, Drug; Ethanol; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Lymphoma; Molecular Weight; Propranolol; Receptors, Adrenergic, beta; Thionucleotides | 1988 |
Photoaffinity labeling the beta-adrenergic receptor with an iodoazido derivative of norepinephrine.
Topics: Adenylyl Cyclases; Affinity Labels; Alprenolol; Animals; Azides; Binding, Competitive; Cell Membrane; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Indicators and Reagents; Isoproterenol; Kinetics; Lung; Magnesium; Norepinephrine; Receptors, Adrenergic, beta; Thionucleotides | 1988 |
Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Female; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hypothyroidism; Isoproterenol; Liver; Pertussis Toxin; Propranolol; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urea; Vasopressins; Virulence Factors, Bordetella | 1988 |
The new positive inotrope sulmazole inhibits the function of guanine nucleotide regulatory proteins by affecting GTP turnover.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Cardiotonic Agents; Cholera Toxin; Colforsin; Cyclic AMP; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1988 |
Adenylate cyclase of catfish hepatocyte membranes: basal properties and sensitivity to catecholamines and glucagon.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Catecholamines; Catfishes; Cell Membrane; Enzyme Activation; Epinephrine; Glucagon; Guanosine Triphosphate; Isoproterenol; Kinetics; Liver; Magnesium; Norepinephrine; Phentolamine; Phenylephrine; Propranolol; Receptors, Adrenergic, beta; Temperature | 1988 |
Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Putative effect of C kinase on alpha s-GTP-catalytic subunit interaction.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Cyclic AMP; Drug Synergism; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lymphoma; Manganese; Phorbols; Protein Kinase C; Protein Kinases; Somatostatin; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Interactions of agonists with beta-adrenergic receptors on S49 lymphoma cells.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Albuterol; Animals; Binding, Competitive; Cell Line; Cell Membrane; Guanosine Triphosphate; Isoproterenol; Lymphoma; Mice; Pindolol; Receptors, Adrenergic, beta; Stereoisomerism; Structure-Activity Relationship | 1985 |
Isoproterenol-sensitive adenylate cyclase in glomeruli isolated from young and adult rat renal cortex.
Topics: Adenylyl Cyclases; Aging; Alkaline Phosphatase; Animals; Enzyme Activation; Fluorides; gamma-Glutamyltransferase; Guanine Nucleotides; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Kidney Cortex; Kidney Glomerulus; Kidney Tubules; Male; Potassium; Potassium Compounds; Propranolol; Rats; Rats, Inbred Strains | 1985 |
A possible mechanism in interaction of a partial agonist with beta-adrenoceptor in guinea-pig taenia caecum: effects of Gpp(NH)p on its two different binding sites.
Topics: Adrenergic beta-Agonists; Animals; Binding Sites; Dihydroalprenolol; Dose-Response Relationship, Drug; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; In Vitro Techniques; Intestines; Isoproterenol; Kinetics; Male; Propanolamines; Receptors, Adrenergic, beta | 1985 |
Hormonal regulation of adenylate cyclase in the stria vascularis of the mouse.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cochlea; Colforsin; Cyclic AMP; Epinephrine; Guanosine Triphosphate; Isoproterenol; Mice; Mice, Inbred CBA; Norepinephrine; Propranolol; Receptors, Adrenergic; Stria Vascularis; Vasopressins | 1985 |
Selective regulation of beta-1 and beta-2 adrenergic receptors by atypical agonists.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Celiprolol; Cells, Cultured; Glioma; Guanosine Triphosphate; Iodine Radioisotopes; Isoproterenol; Pindolol; Propanolamines; Rats; Receptors, Adrenergic, beta | 1985 |
Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Withdrawal of GTP-dependent inhibition.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Line; Chlorides; Colforsin; Cyclic AMP; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lymphoma; Magnesium; Magnesium Chloride; Manganese; Manganese Compounds; Mathematics; Pertussis Toxin; Phorbol Esters; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Studies on responsiveness of hepatoma cells to catecholamines. III. Difference between the receptor-adenylate cyclase regulating systems in AH130 cells and cultured normal rat liver cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cells, Cultured; Clonidine; Epinephrine; Female; Guanosine Triphosphate; Isoproterenol; Liver; Liver Neoplasms, Experimental; Norepinephrine; Pertussis Toxin; Phentolamine; Rats; Virulence Factors, Bordetella | 1986 |
Shallow agonist competition binding curves for beta-adrenergic receptors: the role of tight agonist binding.
Topics: Adrenergic beta-Agonists; Animals; Binding, Competitive; Cattle; Dihydroalprenolol; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Muscles; Receptors, Adrenergic, beta; Time Factors | 1987 |
Carboxyl terminal domain of Gs alpha specifies coupling of receptors to stimulation of adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Mice; Receptors, Adrenergic, beta; Recombinant Proteins; Somatostatin; Structure-Activity Relationship | 1988 |
Comparison between the effects of aging on antagonist and agonist interactions with beta-adrenergic receptors on human mononuclear and polymorphonuclear leukocyte membranes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aging; Drug Interactions; Female; Guanosine Triphosphate; Humans; Isoproterenol; Leukocytes, Mononuclear; Male; Middle Aged; Neutrophils; Pindolol; Receptors, Adrenergic, beta | 1988 |
Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles.
Topics: Adenylyl Cyclases; Animals; Erythrocytes; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Humans; Isoproterenol; Kinetics; Liposomes; Lung; Membrane Proteins; Phosphatidylcholines; Receptors, Adrenergic, beta; Retina; Retinal Pigments; Rhodopsin; Thionucleotides; Transducin | 1985 |
Adenylate cyclase activity in fetal rabbit myocardium.
Topics: Adenylyl Cyclases; Animals; Female; Gestational Age; Guanosine Triphosphate; Heart; Isoproterenol; Kinetics; Myocardium; Pregnancy; Propranolol; Rabbits; Receptors, Adrenergic, beta; Stimulation, Chemical | 1985 |
beta-Adrenoceptor stimulation-induced increase in the number of alpha 2-adrenoceptors of cerebral cortical membranes in rats.
Topics: Animals; Cerebral Cortex; Cholera Toxin; Clonidine; Guanosine Triphosphate; Isoproterenol; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Synaptic Membranes; Yohimbine | 1985 |
Altered binding properties of beta-adrenergic receptors and lack of coupling to adenylate cyclase in P815 mastocytoma cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Dihydroalprenolol; Diterpenes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Mast-Cell Sarcoma; Mice; Mice, Inbred DBA; Neoplasm Proteins; Receptors, Adrenergic, beta; Sarcoma, Experimental; Sodium Fluoride | 1985 |
Lipid requirements for reconstitution of the delipidated beta-adrenergic receptor and the regulatory protein.
Topics: Animals; Erythrocyte Membrane; Glycine max; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Magnesium; Magnesium Chloride; Membrane Lipids; Phospholipids; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1985 |
[Heterologous desensitization of pigeon erythrocyte adenylate cyclase by the catalytic subunit of cAMP-dependent protein kinase].
Topics: Adenylyl Cyclases; Animals; Columbidae; Erythrocyte Membrane; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Macromolecular Substances; Phosphorylation; Protein Kinases; Receptors, Adrenergic, beta; Thionucleotides | 1985 |
Studies on the mechanism of follicle-stimulating hormone-induced desensitization of Sertoli cell adenylyl cyclase in vitro.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cells, Cultured; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Activation; Follicle Stimulating Hormone; Guanosine Triphosphate; Isoproterenol; Kinetics; Male; Rats; Rats, Inbred Strains; Sertoli Cells | 1985 |
Cytosol activator protein from rat reticulocytes requires the stimulatory guanine nucleotide-binding protein for its actions on adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cytosol; Dinoprostone; Enzyme Activation; Erythrocyte Membrane; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Isoproterenol; Lymphoma; Pindolol; Prostaglandins E; Proteins; Rats; Receptors, Adrenergic, beta; Reticulocytes | 1985 |
Effects of clenbuterol and antidepressant drugs on beta adrenergic receptor/N-protein coupling in the cerebral cortex of the rat.
Topics: Animals; Antidepressive Agents; Cerebral Cortex; Clenbuterol; Ethanolamines; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1985 |
Hepatic adenylate cyclase. Development-dependent coupling to the beta-adrenergic receptor in the neonate.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Cell Membrane; Cholera Toxin; Dihydroalprenolol; Fetus; Guanosine Triphosphate; Isoproterenol; Kinetics; Liver; Male; Rabbits; Receptors, Adrenergic, beta | 1985 |
Evidence for two specific affinity states of 3H-antagonist binding to cardiac beta-adrenergic receptors and influence of Gpp(NH)p.
Topics: Alprenolol; Animals; Binding, Competitive; Dihydroalprenolol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Myocardium; Propanolamines; Rats; Receptors, Adrenergic, beta | 1985 |
Comparison of cholinergic inhibition and beta-adrenergic stimulation of adenylate cyclase from rat and guinea-pig hearts: effects of guanine nucleotides and monovalent cations.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Cations, Monovalent; Chlorides; Colforsin; Cytosol; Enzyme Activation; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Lithium; Lithium Chloride; Male; Myocardium; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride; Sodium Fluoride; Tissue Distribution | 1985 |
Uncoupling between beta-adrenoceptors and adenylate cyclase in dog ischemic myocardium.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Colforsin; Coronary Disease; Dogs; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Membranes; Myocardium; Receptors, Adrenergic, beta; Sodium Fluoride; Vasoactive Intestinal Peptide | 1985 |
Modulation of the receptor-coupled adenylate cyclase system in HeLa cells by sodium butyrate.
Topics: Adenylyl Cyclases; Butyrates; Butyric Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; HeLa Cells; Humans; Isoproterenol; Kinetics; Receptors, Adrenergic, beta; Thionucleotides | 1985 |
Expression of beta-adrenergic receptors in synchronous and asynchronous S49 lymphoma cells. II. Relationship between receptor number and response.
Topics: Adenylyl Cyclases; Alprenolol; Cell Cycle; Cell Line; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Lymphoma; Receptors, Adrenergic, beta | 1986 |
Estradiol treatment decreases the lipolytic responses of hamster white adipocytes through a reduction in the activity of the adenylate cyclase catalytic subunit.
Topics: Adenylyl Cyclase Inhibitors; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Clonidine; Cricetinae; Cyclic AMP; Epinephrine; Estradiol; Glycerol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Lipolysis; Male; Mesocricetus; Propanolamines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Theophylline | 1986 |
Gonadotropin-mediated desensitization in a murine Leydig tumor cell line does not alter the regulatory and catalytic components of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cell Line; Cholera Toxin; Chorionic Gonadotropin; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; Drug Tolerance; Guanosine Triphosphate; Isoproterenol; Leydig Cell Tumor; Membrane Fusion; Mice; Protein Biosynthesis; Receptors, Adrenergic, beta | 1986 |
The effect of organophosphorous insecticide Wofatox 50 EC on the adenylate cyclase activity of chicken embryo muscle.
Topics: Adenylyl Cyclases; Animals; Chick Embryo; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Methyl Parathion; Muscles; Parathion | 1986 |
Mechanism of guanine nucleotide regulatory protein-mediated inhibition of adenylate cyclase. Studies with isolated subunits of transducin in a reconstituted system.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cattle; Cricetinae; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Humans; Isoproterenol; Liposomes; Macromolecular Substances; Magnesium; Magnesium Chloride; Membrane Proteins; Receptors, Adrenergic, beta; Thionucleotides; Transducin | 1986 |
Autonomic interactions in the aging heart: age-associated decrease in muscarinic cholinergic receptor mediated inhibition of beta-adrenergic activation of adenylate cyclase.
Topics: Adenylyl Cyclases; Aging; Animals; Atropine; Carbachol; Cell Membrane; Enzyme Activation; Guanosine Triphosphate; Isoproterenol; Male; Myocardium; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Muscarinic | 1986 |
Desensitization of beta-adrenergic receptor-coupled adenylate cyclase in cerebral cortex after in vivo treatment of rats with desipramine.
Topics: Adenylyl Cyclases; Animals; Cerebral Cortex; Desipramine; Drug Tolerance; Enzyme Activation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Iodocyanopindolol; Isoproterenol; Kinetics; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1986 |
Atrial natriuretic factor receptors are negatively coupled to adenylate cyclase in cultured atrial and ventricular cardiocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Animals, Newborn; Cells, Cultured; Colforsin; Dopamine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart Atria; Heart Ventricles; Isoproterenol; Myocardium; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thionucleotides | 1986 |
GDP activates rabbit heart adenylate cyclase, but does not support stimulation by isoproterenol: a re-appraisal of the control mechanism.
Topics: Adenylyl Cyclases; Animals; Enzyme Activation; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Myocardium; Nucleoside-Diphosphate Kinase; Protein Binding; Rabbits; Receptors, Adrenergic, beta; Sarcolemma | 1986 |
Fasting increases fat cell adenylate cyclase sensitivity to stimulatory agonists through enhanced ability of the stimulatory regulatory component Ns to dissociate.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cholera Toxin; Colforsin; Fasting; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Macromolecular Substances; Male; Manganese; Rats; Receptors, Adrenergic, beta | 1986 |
Characteristics of the beta-adrenergic stimulation of adenylate cyclase activity in rat ventral prostate and its modulation by androgens.
Topics: Adenylyl Cyclases; Androgens; Animals; Colforsin; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Guanosine Triphosphate; Isoproterenol; Male; Norepinephrine; Propranolol; Prostate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1986 |
Pertussis toxin attenuates atrial natriuretic factor-mediated inhibition of adenylate cyclase. Involvement of inhibitory guanine nucleotide regulatory protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Aorta; Atrial Natriuretic Factor; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Male; Molecular Weight; NAD; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thionucleotides; Virulence Factors, Bordetella | 1987 |
Functional differences in the beta gamma complexes of transducin and the inhibitory guanine nucleotide regulatory protein.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cattle; Cricetinae; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Macromolecular Substances; Membrane Proteins; Receptors, Adrenergic, beta; Retina; Structure-Activity Relationship; Transducin | 1987 |
Reduction in the activity of the stimulatory guanine nucleotide-binding protein in the myocardium of spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypertension; Isoproterenol; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic, beta; Sarcolemma; Thionucleotides | 1987 |
Multiple effects of phorbol esters on hormone-sensitive adenylate cyclase activity in S49 lymphoma cells.
Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Lymphoma; Phorbol Esters; Protein Kinase C; Receptors, Adrenergic, beta; Sodium Fluoride; Temperature; Tetradecanoylphorbol Acetate | 1987 |
Unimpaired coupling of phosphorylated, desensitized beta-adrenoceptor to Gs in a reconstitution system.
Topics: Adenylyl Cyclases; Animals; Colforsin; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Phosphorylation; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1987 |
Functional and structural characterization of the two beta 1-adrenoceptor forms in turkey erythrocytes with molecular masses of 50 and 40 kilodaltons.
Topics: Animals; Chromatography, Affinity; Erythrocyte Membrane; Glycoside Hydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Iodocyanopindolol; Isoproterenol; Kinetics; Molecular Weight; Pindolol; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1987 |
Development of muscarinic cholinergic inhibition of adenylate cyclase in embryonic chick heart. Its relationship to changes in the inhibitory guanine nucleotide regulatory protein.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Atropine; Carbachol; Chick Embryo; GTP-Binding Proteins; Guanosine Triphosphate; Heart; Isoproterenol; Kinetics; Myocardium; Pertussis Toxin; Receptors, Muscarinic; Virulence Factors, Bordetella | 1986 |
Cytochemical localization of adenylate cyclase activity in heart tissue with cerium.
Topics: Adenylyl Cyclases; Animals; Cerium; Enzyme Activation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Histocytochemistry; Isoproterenol; Male; Microscopy, Electron; Myocardium; Sodium Fluoride | 1986 |
Stimulatory and inhibitory regulation of myocardial adenylate cyclase by 5'-guanylyl-imidodiphosphate.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Magnesium; Manganese; Myocardium; Rats | 1987 |
Type II heat-labile enterotoxin of Escherichia coli activates adenylate cyclase in human fibroblasts by ADP ribosylation.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alprostadil; Bacterial Toxins; Carbachol; Cholera Toxin; Dithiothreitol; Enterotoxins; Enzyme Activation; Escherichia coli Proteins; Fibroblasts; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Isoproterenol; NAD; Trypsin | 1987 |
Expression of cDNAs for G proteins in Escherichia coli. Two forms of Gs alpha stimulate adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Brain Chemistry; Cattle; Centrifugation, Density Gradient; Cholera Toxin; Chromatography; DNA; DNA-Directed RNA Polymerases; DNA, Recombinant; Escherichia coli; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Plasmids; T-Phages; Thionucleotides; Transformation, Genetic | 1987 |
Possible involvement of pertussis toxin substrates (Gi, Go) in desipramine-induced refractoriness of adenylate cyclase in cerebral cortices of rats.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cerebral Cortex; Desipramine; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Molecular Weight; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1988 |
Subunit dissociation is the mechanism for hormonal activation of the Gs protein in native membranes.
Topics: Animals; Cell Line; Cell Membrane; Enzyme-Linked Immunosorbent Assay; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Liver; Lymphoma; Macromolecular Substances; Rabbits; Thionucleotides | 1988 |
Specific properties of epithelial and stromal cells from the endometrium of cows.
Topics: Adenylyl Cyclases; Animals; Cattle; Cells, Cultured; Dinoprostone; Endometrium; Epithelial Cells; Epithelium; Female; Guanosine Triphosphate; Isoproterenol; Prostaglandins E | 1988 |
Effect of the genetic background and specific mutation on adenylate cyclase activity in obesity syndromes.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Diabetes Mellitus, Experimental; Enzyme Activation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Obesity | 1988 |
The regulation of adenylate cyclase in liver membranes of lean and obese mice.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Enzyme Activation; Glucagon; Guanosine Triphosphate; Isoproterenol; Liver; Magnesium; Magnesium Chloride; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Obesity; Pertussis Toxin; Propranolol; Virulence Factors, Bordetella; Yohimbine | 1988 |
The embryo influences adenylate cyclase activity and hormonal response in rabbit myometrium during early pregnancy.
Topics: Adenylyl Cyclases; Animals; Dinoprostone; Embryo, Mammalian; Female; Guanosine Triphosphate; Isoproterenol; Kinetics; Myometrium; Pregnancy; Pseudopregnancy; Rabbits; Reference Values; Sodium Fluoride | 1988 |
Impaired cardiac muscarinic receptor function in dogs with heart failure.
Topics: Adenylyl Cyclases; Animals; Atropine; Carbachol; Dogs; Female; Guanosine Triphosphate; Heart Failure; Heart Ventricles; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Myocardium; Oxotremorine; Receptors, Muscarinic; Sarcolemma | 1988 |
Application of [125I]iodocyanopindolol to measure 5-hydroxytryptamine1B receptors in the brain of the rat.
Topics: 5,7-Dihydroxytryptamine; Animals; Brain Chemistry; Buffers; Guanosine Triphosphate; Injections, Intraventricular; Iodocyanopindolol; Isoproterenol; Kinetics; Male; Methods; Pindolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin | 1988 |
Lithium inhibits adrenergic and cholinergic increases in GTP binding in rat cortex.
Topics: Animals; Atropine; Bipolar Disorder; Carbachol; Cerebral Cortex; Guanosine Triphosphate; Isoproterenol; Lithium; Male; Propranolol; Rats | 1988 |
Guanine nucleotide binding in human placental syncytiotrophoblast membranes and comparative regulation of adenylate cyclase in syncytiotrophoblast, turkey erythrocyte and bovine calf testes membranes by guanosine-5'-triphosphate.
Topics: Adenylyl Cyclases; Animals; Cattle; Erythrocytes; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Male; Membranes; Placenta; Testis; Trophoblasts; Turkeys | 1988 |
Guanine nucleotide activation of adenylate cyclase in saponin permeabilized glioma cells.
Topics: Adenylyl Cyclases; Cell Line; Cell Membrane Permeability; Enzyme Activation; Glioma; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Saponins; Thionucleotides | 1986 |
17 Beta-estradiol-sensitivity of cultured myometrial cells.
Topics: Adenylyl Cyclases; Animals; Estradiol; Female; Guanosine Triphosphate; Isoproterenol; Myometrium; Rats; Rats, Inbred Strains; Thymidine | 1987 |
Adenylate cyclase stimulation by VIP in rat and human parotid membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Isoproterenol; Male; Parotid Gland; Rats; Rats, Inbred Strains; Species Specificity; Vasoactive Intestinal Peptide | 1987 |
Basal and stimulated adenylate cyclase activity in the gill epithelium of the rainbow trout.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cations, Divalent; Cell Membrane; Gills; Guanosine Triphosphate; Hydrogen-Ion Concentration; Isoproterenol; Kinetics; Protein Biosynthesis; Salmonidae; Sodium Fluoride; Temperature; Trout | 1987 |
A transplantable rat Leydig cell tumor--3. Isoproterenol and prostaglandin E1 (PGE1) responsive adenylyl cyclase (AC). Regulatory effects of nucleotides and magnesium.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Guanosine Triphosphate; Isoproterenol; Kinetics; Leydig Cell Tumor; Magnesium; Neoplasm Transplantation; Nucleotides; Rats | 1986 |
Effect of chronic administration of doxorubicin on cardiac adenylate cyclase activity in mice.
Topics: Adenylyl Cyclases; Animals; Colforsin; Doxorubicin; Guanosine Triphosphate; Heart; Isoproterenol; Male; Mice; Myocardium; Organ Size; Sodium Fluoride | 1986 |
Maintenance of whole cell isoproterenol and forskolin responsiveness in adenylate cyclase of permeabilized cells.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Astrocytoma; Cell Line; Cell Membrane Permeability; Colforsin; Digitonin; Guanosine Triphosphate; Isoproterenol; Kinetics; Rats | 1986 |
Forskolin activation of adenylate cyclase in mouse parotid membranes.
Topics: Adenylyl Cyclases; Animals; Colforsin; Enzyme Activation; Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Mice; Parotid Gland; Thionucleotides | 1986 |
In situ analysis of adenylate cyclase activity in permeabilized rat adipocytes: sensitivity to GTP, isoproterenol, and N6-(phenylisopropyl)adenosine.
Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane Permeability; Digitonin; Guanosine Triphosphate; Isoproterenol; Kinetics; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains | 1986 |
Age dependence of adenylate cyclase in guinea pig ureter homogenate.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Animals; Colforsin; Enzyme Activation; Ethanol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Male; Muscle Contraction; Propranolol; Sodium Fluoride; Ureter | 1986 |
The hysteretic effect of Gpp(NH)p on adenylate cyclase is not altered by Mg2+ in adipocyte membranes of ob/ob mice.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cholera Toxin; Colforsin; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Magnesium; Male; Mice; Mice, Obese; Pertussis Vaccine; Regression Analysis; Sodium Fluoride | 1986 |
Modulation by n-alkanols of rat cardiac adenylate cyclase activity.
Topics: Adenylyl Cyclases; Alcohols; Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Myocardium; Rats; Secretin; Sodium Fluoride; Structure-Activity Relationship | 1986 |
Reconstitution of muscarinic cholinergic inhibition of adenylate cyclase activity in homogenates of embryonic chick hearts by membranes of adult chick hearts.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Carbachol; Cell Extracts; Cell Membrane; Chick Embryo; Chickens; Guanosine Triphosphate; Heart; Isoproterenol; Myocardium; Pertussis Toxin; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tissue Extracts; Virulence Factors, Bordetella | 1987 |
Chymotrypsin selectively decreases forskolin stimulation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Chymotrypsin; Colforsin; Erythrocyte Membrane; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Thionucleotides; Turkeys | 1985 |
Ninhibin: a sperm factor attenuates the atrial natriuretic factor mediated inhibition of adenylate cyclase: possible involvement of inhibitory guanine nucleotide regulatory protein.
Topics: Acrosin; Adenylyl Cyclase Inhibitors; Animals; Aorta; Cattle; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Endopeptidases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Natriuretic Agents; Proteins; Rats; Thionucleotides | 1985 |
Membrane-bound adenylate cyclase activity in the testis of the blue fox.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Foxes; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Magnesium; Male; Manganese; Membranes; Testis; Time Factors | 1985 |
Stimulation of the adenylate cyclase activity of rabbit bone marrow immature erythroblasts by erythropoietin and haemin.
Topics: Adenylyl Cyclases; Animals; Bone Marrow; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Erythroblasts; Erythropoietin; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heme; Hemin; Isoproterenol; Rabbits; Thionucleotides | 1986 |
Characterization of the adenylate cyclase of the rat corpus luteum during luteolysis induced by a prostaglandin F2 alpha analogue.
Topics: Adenylyl Cyclases; Animals; Cloprostenol; Colforsin; Corpus Luteum; Drug Synergism; Enzyme Activation; Female; Guanosine Triphosphate; Isoproterenol; Luteolytic Agents; Magnesium; Prostaglandins F, Synthetic; Rats; Rats, Inbred Strains; RNA Cap Analogs | 1986 |
Adenylate cyclase activity and motor behavior following cerebral ischemia in the unanesthetized gerbil.
Topics: Adenylyl Cyclases; Animals; Carotid Arteries; Cerebral Cortex; Colforsin; Diterpenes; Gerbillinae; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Ischemic Attack, Transient; Isoproterenol; Ligation; Male; Motor Activity; Time Factors | 1985 |
Regulation by various hormones and agents of adenosine-3',5'-monophosphate levels in islets of Langerhans of rats.
Topics: Adenine; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Cresols; Cyclic AMP; Epinephrine; Glucagon; Glucose; Guanosine Triphosphate; Hormones; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Leucine; Phenformin; Phenoxybenzamine; Phentolamine; Propanolamines; Propranolol; Propylamines; Prostaglandins; Rats; Receptors, Adrenergic; Secretin; Sotalol; Theophylline; Thyrotropin; Tolbutamide; Tritium | 1974 |
Adenylate cyclase activity in isolated rat islets of Langerhans. Effects of agents which alter rates of insulin secretion.
Topics: Adenylyl Cyclases; Animals; Arginine; Epinephrine; Fluorides; Glucagon; Glucose; Glyburide; Guanosine Triphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Kinetics; Leucine; Male; Norepinephrine; Nucleotides; Phenoxybenzamine; Phosphorus Radioisotopes; Potassium; Propranolol; Prostaglandins; Rats; Xylitol | 1973 |
[Influence of various hormones on formation of adenosine-3':5'-monophosphate and guanosine-3':5'-monophosphate by particulate preparations from rat kidney].
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Angiotensin II; Animals; Calcitonin; Cell Membrane; Cyclic AMP; Cyclic GMP; Diabetes Insipidus; Guanosine Triphosphate; Hormones; Isoproterenol; Kidney; Kidney Tubules; Magnesium; Male; Norepinephrine; Oxytocin; Parathyroid Hormone; Prostaglandins; Rats; Vasopressins; Water | 1972 |
Cyclic nucleotide hydrolysis: some possible natural regulators in retina and rod outer segments.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Ascorbic Acid; Calcium; Cattle; Centrifugation, Density Gradient; Cyclic AMP; Cyclic GMP; Diphosphates; Dithiothreitol; Dopamine; Epinephrine; Guanosine Triphosphate; Hydroxymercuribenzoates; Isoproterenol; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Photoreceptor Cells; Retina; Tritium | 1974 |
Stimulation of catecholamine-sensitive adenylate cyclase by 5'-guanylyl-imidodiphosphate.
Topics: Adenylyl Cyclases; Adipose Tissue; Allosteric Regulation; Animals; Anura; Cell Membrane; Cytosine Nucleotides; Dogs; Enzyme Activation; Erythrocytes; Female; Guanine Nucleotides; Guanosine Triphosphate; Inosine Nucleotides; Isoproterenol; Magnesium; Organ Specificity; Phosphorus Radioisotopes; Propranolol; Protein Binding; Rats; Species Specificity; Structure-Activity Relationship; Uracil Nucleotides | 1974 |
Binding of 5'-guanylyl-imidodiphosphate to turkey erythrocyte membranes and effects on beta-adrenergic-activated adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Chromatography, Ion Exchange; Erythrocytes; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Imides; Isoproterenol; Kinetics; Norepinephrine; Phentolamine; Phosphorus Radioisotopes; Propranolol; Protein Binding; Receptors, Drug; Tritium; Turkeys | 1974 |
Some properties of RNA polymerase of rat submaxillary gland nuclei and effects of isoproterenol on the enzyme.
Topics: Adenosine Triphosphate; Ammonium Sulfate; Animals; Carbon Radioisotopes; Cell Nucleus; Cytosine Nucleotides; DNA; DNA-Directed RNA Polymerases; Enzyme Activation; Female; Guanosine Triphosphate; Isoproterenol; Liver; Magnesium; Manganese; RNA; Submandibular Gland; Uracil Nucleotides | 1974 |
The effects of nucleotides on the expression of beta-adrenergic adenylate cyclase activity in membranes from turkey erythrocytes.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Catecholamines; Cell Membrane; Erythrocytes; Fluorides; Guanosine Triphosphate; Inosine Nucleotides; Isoproterenol; Kinetics; Nucleotides; Phentolamine; Phosphorus Radioisotopes; Propranolol; Protein Binding; Receptors, Adrenergic; Turkeys | 1974 |
Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.
Topics: Adenylyl Cyclases; Animals; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Phorbols; Phosphorylation; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Thionucleotides; Time Factors; Turkeys | 1984 |
Catecholamine responsive adenylate cyclase in human myocardial preparations. Properties and optimalization of assay conditions.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Cyclic AMP; GTP-Binding Proteins; Guanosine Monophosphate; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Isoproterenol; Magnesium; Myocardium; Propranolol; Receptors, Adrenergic; Receptors, Catecholamine; Receptors, Cell Surface | 1984 |
Reconstitution of a hormone-sensitive adenylate cyclase system. The pure beta-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit.
Topics: Adenylyl Cyclases; Animals; Cattle; Caudate Nucleus; Cell Membrane; Cricetinae; Erythrocytes; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Humans; Isoproterenol; Kinetics; Liposomes; Lung; Magnesium; Molecular Weight; Phosphatidylcholines; Receptors, Adrenergic, beta; Receptors, Cell Surface | 1984 |
Characterization of a beta-adrenergic receptor in porcine trachealis muscle.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Dihydroalprenolol; GTP-Binding Proteins; Guanosine Monophosphate; Guanosine Triphosphate; Isoproterenol; Microscopy, Electron; Muscle Contraction; Muscle, Smooth; Receptors, Adrenergic, beta; Stimulation, Chemical; Swine; Trachea | 1984 |
[Effect of prostaglandin E1 on the cyclic adenosine-3',5'--monophosphate system and radiosensitivity of B-82 cells cultured in vitro].
Topics: Adenylyl Cyclases; Alprostadil; Animals; Clone Cells; Cyclic AMP; Dose-Response Relationship, Drug; Guanosine Triphosphate; Isoproterenol; L Cells; Mice; Prostaglandins E; Radiation Tolerance; Sodium Fluoride | 1984 |
Reconstitution of catecholamine-stimulated binding of guanosine 5'-O-(3-thiotriphosphate) to the stimulatory GTP-binding protein of adenylate cyclase.
Topics: Animals; Drug Stability; Erythrocyte Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hot Temperature; Isoproterenol; Kinetics; Liposomes; Liver; Magnesium; Protein Binding; Protein Denaturation; Rabbits; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1984 |
Catecholamine-stimulated guanosine 5'-O-(3-thiotriphosphate) binding to the stimulatory GTP-binding protein of adenylate cyclase: kinetic analysis in reconstituted phospholipid vesicles.
Topics: Animals; Dose-Response Relationship, Drug; Erythrocyte Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Liposomes; Liver; Magnesium; Protein Binding; Rabbits; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1984 |
Endogenous proteinases modulate the function of the beta-adrenergic receptor-adenylate cyclase system.
Topics: Adenylyl Cyclases; Affinity Labels; Animals; Azides; Binding, Competitive; Dihydroalprenolol; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Lung; Male; Membrane Proteins; Molecular Weight; Propanolamines; Protease Inhibitors; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1984 |
Beta-adrenergic receptor interaction with guanosine triphosphate in fetal rabbit myocardial membranes.
Topics: Animals; Binding, Competitive; Fetus; Gestational Age; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Membranes; Myocardium; Pindolol; Propranolol; Rabbits; Receptors, Adrenergic, beta | 1984 |
Desensitized beta-adrenoceptors of C6-glioma cells have distinct binding properties.
Topics: Animals; Cell Line; Cell Membrane; Glioma; Guanosine Triphosphate; Isoproterenol; Rats; Receptors, Adrenergic, beta; Solubility; Subcellular Fractions | 1984 |
Sodium regulation of hormone-sensitive adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Alprostadil; Animals; Blood Platelets; Cricetinae; Cyclic AMP; Epinephrine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; In Vitro Techniques; Isoproterenol; Lymphoma; Prostaglandins E; Receptors, Adrenergic, beta; Receptors, Cell Surface; Sodium Chloride; Thionucleotides | 1984 |
Role of guanine nucleotides in hormonal activation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Cholera Toxin; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; GTP Phosphohydrolases; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Propranolol; Turkeys | 1981 |
Differentiation-dependent expression of catecholamine-stimulated adenylate cyclase. Roles of the beta-receptor and G/F protein in differentiating 3T3-L1 adipocytes.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adipose Tissue; Animals; Cell Differentiation; Cell Membrane; Cells, Cultured; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Mice; Pindolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Cell Surface | 1981 |
A reconstitution assay for the guanine nucleotide regulatory protein of the adenylate cyclase system using turkey erythrocyte membranes as the acceptor preparation.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cyclic AMP; Erythrocyte Membrane; Erythrocytes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Propranolol; Rats; Rats, Inbred Strains; Turkeys | 1982 |
High and low (Gpp(NH)p-sensitive) affinity sites for beta 2-adrenergic blockers as antagonists of isoproterenol in the field-stimulated rat vas deferens.
Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Electric Stimulation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Timolol; Vas Deferens | 1982 |
A simple test for enhanced guanyl nucleotide exchange in brain adenylate cyclase systems activated by neurotransmitters.
Topics: Adenylyl Cyclases; Animals; Brain; Enzyme Activation; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Neurotransmitter Agents; Pineal Gland; Propranolol; Rats; Thionucleotides | 1983 |
Coexistence of beta 1- and beta 2-adrenoceptors in human right atrium. Direct identification by (+/-)-[125I]iodocyanopindolol binding.
Topics: Adenylyl Cyclases; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Child; Epinephrine; Guanosine Triphosphate; Heart Atria; Humans; Iodocyanopindolol; Isoproterenol; Middle Aged; Norepinephrine; Pindolol; Receptors, Adrenergic, beta | 1983 |
In vitro interactions of agonists and antagonists with beta-adrenergic receptors.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Epinephrine; Guanosine Triphosphate; Humans; Isoproterenol; Magnesium; Models, Biological; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; Sulfhydryl Reagents; Thermodynamics | 1984 |
Activation of the inhibitory GTP-binding protein of adenylate cyclase, Gi, by beta-adrenergic receptors in reconstituted phospholipid vesicles.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bacterial Proteins; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Lipid Bilayers; Liver; NAD; Pertussis Toxin; Rabbits; Receptors, Adrenergic, beta; Receptors, Cell Surface; Thionucleotides; Virulence Factors, Bordetella | 1984 |
Absence of high-affinity binding sites for beta-adrenergic blockers and lack of adenyl cyclase stimulation to beta-adrenergic stimulators in most normal and adenomatous human thyroid tissues.
Topics: Adenoma; Adenylyl Cyclases; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Thyroid Gland; Thyroid Neoplasms; Thyrotropin | 1984 |
Enhanced adenylate cyclase activity of turkey erythrocytes following treatment with beta-adrenergic receptor antagonists.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Enzyme Activation; Erythrocyte Membrane; Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Propranolol; Radioisotopes; Radioligand Assay; Receptors, Adrenergic, beta; Tritium; Turkeys | 1984 |
A hormone-independent rise of adenosine 3',5'-monophosphate desensitizes coupling of beta-adrenergic receptors to adenylate cyclase in rat glioma C6-cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Carrier Proteins; Cholera Toxin; Cyclic AMP; Dihydroalprenolol; Fluorides; Glioma; Guanosine Triphosphate; Isoproterenol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1980 |
Inhibition of rat salivary gland adenylate cyclase by glycosaminoglycans and high molecular weight polyanions.
Topics: Adenylyl Cyclase Inhibitors; Animals; Dextran Sulfate; Dextrans; Dose-Response Relationship, Drug; Glycosaminoglycans; Guanosine Triphosphate; Heparin; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Inbred Strains; Sodium Fluoride; Submandibular Gland | 1984 |
Mechanisms of prostaglandin action on human fat cell lipolysis.
Topics: Adipose Tissue; Dinoprostone; Guanosine Triphosphate; Humans; Isoproterenol; Lipolysis; Prostaglandin D2; Prostaglandins; Prostaglandins D; Prostaglandins E; Sodium Chloride; Theophylline | 1983 |
Selective alteration of secretin-stimulated cardiac adenylate cyclase activity in streptozotocin-diabetic rats.
Topics: Adenylyl Cyclases; Animals; Diabetes Mellitus, Experimental; Glucagon; Guanosine Triphosphate; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred Strains; Secretin; Sodium Fluoride; Streptozocin | 1983 |
Guanosine triphosphate: an endogenous compound in the rabbit cerebellar cortex which couples the beta-adrenergic receptor to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cerebellar Cortex; Culture Techniques; Dihydroalprenolol; Enzyme Activation; Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1980 |
Fluoride stimulation of adenylate cyclase is dependent on the guanine nucleotide regulatory protein.
Topics: Adenylyl Cyclases; Animals; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Membrane Proteins; Temperature; Turkeys | 1980 |
The role of the guanine nucleotide exchange reaction in the regulation of the beta-adrenergic receptor and in the actions of catecholamines and cholera toxin on adenylate cyclase in turkey erythrocyte membranes.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Guanine Nucleotides; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Turkeys | 1980 |
Properties of adenylate cyclase and cyclic nucleotide phosphodiesterase in hamster isolated capillary preparations.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Animals; Caffeine; Capillaries; Cricetinae; Endothelium; Enzyme Activation; Epididymis; Guanosine Triphosphate; Isoproterenol; Kinetics; Male | 1980 |
Tumour promoter uncouples beta-adrenergic receptor from adenyl cyclase in mouse epidermis.
Topics: Adenylyl Cyclases; Animals; Cell-Free System; Cyclic AMP; Enzyme Activation; Epidermis; Female; Guanosine Triphosphate; Isoproterenol; Membrane Fluidity; Mice; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1980 |
Hormone receptor-mediated stimulation of adenylyl cyclase systems. Nucleotide effects and analysis in terms of a simple two-state model for the basic receptor-affected enzyme.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Epoprostenol; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Liver; Rats; Receptors, Cell Surface | 1980 |
Reconstitution of turkey erythrocyte beta-adrenergic receptors into human erythrocyte acceptor membranes. Demonstration of guanine nucleotide regulation of agonist affinity.
Topics: Animals; Erythrocyte Membrane; Erythrocytes; Guanosine Triphosphate; Humans; Isomerism; Isoproterenol; Kinetics; Pindolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Species Specificity; Turkeys | 1980 |
Inhibition and activation of fat cell adenylate cyclase by GTP is mediated by structures of different size.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cell Membrane; Electrons; Enzyme Activation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Rats; Receptors, Cell Surface | 1980 |
Alpha-Adrenergic receptors modulate beta-receptor affinity in rat kidney membranes.
Topics: Alprenolol; Animals; Cell-Free System; Clonidine; Guanosine Triphosphate; Isoproterenol; Kidney; Membranes; Phentolamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1980 |
Role of cyclic AMP in human adipose tissue lipolysis.
Topics: Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Adipose Tissue; Cyclic AMP; Epinephrine; Fasting; Fatty Acids, Nonesterified; Glycerol; Guanosine Triphosphate; Humans; Isoproterenol; Kinetics; Lipid Mobilization; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1980 |
Regulation of hormone-receptor coupling to adenylyl cyclase. Effects of GTP and GDP.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Corpus Luteum; Erythrocyte Membrane; Female; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Kinetics; Lymphoma; Mice; Prostaglandins E; Receptors, Cell Surface; Turkeys | 1980 |
Independent mechanisms of adenosine activation and inhibition of the turkey erythrocyte adenylate cyclase system.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Enzyme Activation; Erythrocytes; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Turkeys | 1980 |
Stimulation of a D-2 dopamine receptor in the intermediate lobe of the rat pituitary gland decreases the responsiveness of the beta-adrenoceptor: biochemical mechanism.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Cell-Free System; Dose-Response Relationship, Drug; Fluphenazine; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Male; Pituitary Gland; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Dopamine | 1981 |
Beta-adrenergic receptor-adenylate cyclase alterations during the postnatal development of skeletal muscle.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Cell Membrane; Dihydroalprenolol; Epinephrine; Female; Guanosine Triphosphate; Isoproterenol; Muscle Development; Norepinephrine; Phospholipids; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sarcolemma; Sodium Fluoride; Sodium-Potassium-Exchanging ATPase | 1980 |
Correlation of beta-adrenergic receptor-stimulated [3H]GDP release and adenylate cyclase activation. Differences between frog and turkey erythrocyte membranes.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Erythrocyte Membrane; Erythrocytes; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Isoproterenol; Phentolamine; Prostaglandins E; Ranidae; Receptors, Adrenergic; Receptors, Adrenergic, beta; Species Specificity; Turkeys | 1981 |
Interactions of agonists and antagonists with beta-adrenergic receptors on intact L6 muscle cells.
Topics: Animals; Cell Membrane; Cells, Cultured; Guanosine Triphosphate; Isoproterenol; Kinetics; Muscles; Pindolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1980 |
Receptor-specific desensitization of the S49 lymphoma cell adenylyl cyclase. Unaltered behavior of the regulatory component.
Topics: Adenylyl Cyclases; Animals; Cell Line; Enzyme Activation; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lymphoma; Magnesium; Mice; Neoplasms, Experimental; Prostaglandins E; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1981 |
Halothane effect on beta-adrenergic receptors in canine myocardium.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Dihydroalprenolol; Dogs; Female; Guanosine Triphosphate; Halothane; Heart; Isoproterenol; Male; Myocardium; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1981 |
High and low affinity states of beta-adrenergic receptors and their coupling with the adenylate cyclase in a muscle cell line.
Topics: Adenylyl Cyclases; Albuterol; Animals; Cell Line; Epinephrine; Guanosine Triphosphate; Isoproterenol; Kinetics; Muscles; Norepinephrine; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1981 |
Age-associated decrease of adenylate cyclase activity in rat myocardium.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aging; Animals; Cyclic AMP; Female; Guanosine Triphosphate; Isoproterenol; Kinetics; Myocardium; Rats; Sodium Fluoride | 1981 |
Interaction of guanine nucleotides with adenylate cyclase in normal and spontaneously transformed RL-RP-C cloned rat hepatocytes.
Topics: Adenylyl Cyclases; Animals; Cell Transformation, Neoplastic; Cholera Toxin; Clone Cells; Dose-Response Relationship, Drug; Guanine Nucleotides; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Rats | 1981 |
Molecular pharmacology of adenylate cyclase-coupled alpha- and beta-adrenergic receptors.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Blood Platelets; Cell Membrane; Dihydroalprenolol; Epinephrine; Erythrocyte Membrane; Erythrocytes; Guanosine Triphosphate; Isoproterenol; Kinetics; Ranidae; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1981 |
Reconstitution of the primary action of a hormone receptor using solubilized components.
Topics: Adenylyl Cyclases; Animals; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Propranolol; Ranidae; Receptors, Cell Surface | 1981 |
Hormone-sensitive adenylate cyclase in glomerular cells: possible role for inflammatory diseases of the glomerulus.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Enzyme Activation; Glomerulonephritis; Guanosine Triphosphate; Histamine; Histamine Antagonists; In Vitro Techniques; Isoproterenol; Kidney Glomerulus; Prostaglandins E; Rats | 1981 |
Choleragen-stimulated release of guanyl nucleotides from turkey erythrocyte membranes.
Topics: Animals; Cholera Toxin; Erythrocyte Membrane; Erythrocytes; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Kinetics; Receptors, Cell Surface; Turkeys | 1982 |
Human mutation affecting hormone-sensitive adenylate cyclase.
Topics: Adenylyl Cyclases; Cholera Toxin; Cyclic AMP; Erythrocyte Membrane; Erythrocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Isoproterenol; Mutation; Pseudohypoparathyroidism; Thionucleotides | 1981 |
3,3',5-triiodothyronine administration in vivo modulates the hormone-sensitive adenylate cyclase system of rat hepatocytes.
Topics: Adenylyl Cyclases; Animals; Benzyl Alcohols; Cholera Toxin; Cyclic AMP; Epinephrine; Female; Glucagon; Guanosine Triphosphate; Hormones; Hyperthyroidism; Isoproterenol; Liver; Pindolol; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Triiodothyronine; Triiodothyronine, Reverse | 1982 |
Modulation by islet-activating protein of adenylate cyclase activity in C6 glioma cells.
Topics: Adenine Nucleotides; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bacterial Proteins; Calcium; Cell Line; Cell Membrane; Cyclic AMP; Glioma; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hypoglycemic Agents; Isoproterenol; Pertussis Toxin; Rats; Virulence Factors, Bordetella | 1982 |
Large potentiation of agonist response in intact cells is produced by increases only in GTP-dependent adenylate cyclase activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Cells, Cultured; Cyclic AMP; Drug Synergism; Guanosine Triphosphate; Insulin; Isoproterenol; Picolinic Acids; Rats | 1981 |
On the mechanism of isoproterenol-induced desensitization of adenylate cyclase in cultured differentiated hepatocytes.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Line; Clone Cells; Cyclic AMP; Dihydroalprenolol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Liver; Rats; Sodium Fluoride | 1982 |
Evidence for a defect in the number of beta-adrenergic receptors and in the adenylate cyclase responsiveness to guanine nucleotides in fat cells after adrenalectomy.
Topics: Adenosine Deaminase; Adenylyl Cyclases; Adipose Tissue; Adrenalectomy; Animals; Cell Membrane; Dihydroalprenolol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1982 |
Biochemical and physiological studies of the beta-adrenoceptor and the D-2 dopamine receptor in the intermediate lobe of the rat pituitary gland: a review.
Topics: Animals; Apomorphine; Catecholamines; Cyclic AMP; Fluphenazine; Guanosine Triphosphate; Isoproterenol; Melanocyte-Stimulating Hormones; Pituitary Gland; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2 | 1982 |
Biological maturation and beta-adrenergic effectors: pre- and postnatal development of the adenylate cyclase system in the rabbit heart.
Topics: Adenylyl Cyclases; Animals; Female; Fetal Heart; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; Isoproterenol; Magnesium; Myocardial Contraction; Myocardium; Pregnancy; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sodium Fluoride | 1982 |
alpha and beta-adrenoceptor coupling to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Dihydroalprenolol; Guanosine Triphosphate; Isoproterenol; Lung; Microsomes; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1982 |
Blockade of heterologous desensitization of prostate adenylate cyclase without blockade of homologous down regulation of receptors or loss of GTP regulation of agonist binding.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Calcimycin; Dihydroalprenolol; Guanosine Triphosphate; Isoproterenol; Male; Potassium; Prostate; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1983 |
Effects of experimental insulin-dependent diabetes on the beta-adrenergic-receptor-coupled adenylate-cyclase system and lipolysis in fat cells of the rat.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cyclic AMP; Diabetes Mellitus, Experimental; Fluorides; Guanosine Triphosphate; Insulin; Isoproterenol; Lipolysis; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1983 |
Distinctions in beta-adrenergic receptor interactions with the magnesium-guanine nucleotide coupling proteins in turkey erythrocyte and S49 lymphoma membranes.
Topics: Animals; Blood Proteins; Cell Membrane; Edetic Acid; Erythrocyte Membrane; Erythrocytes; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Isoproterenol; Kinetics; Lymphoma; Magnesium; Membrane Proteins; Mice; Neoplasms, Experimental; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Cell Surface; Turkeys | 1982 |
Regulation of adenylate cyclase by hormones and guanine nucleotides in normal, desensitized, and resensitized rabbit heart.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Dose-Response Relationship, Drug; Enzyme Activation; Epinephrine; Female; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Histamine; Isoproterenol; Male; Myocardium; Rabbits; Receptors, Adrenergic, beta; Sarcolemma | 1982 |
Evidence that the D-2 dopamine receptor in the intermediate lobe of the rat pituitary gland is associated with an inhibitory guanyl nucleotide component.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Cholera Toxin; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Pituitary Gland; Rats; Receptors, Adrenergic, beta; Receptors, Dopamine; Spiperone | 1983 |
Guanosine 5'-triphosphate modulation of S-adenosyl-L-methionine-mediated methylation of phosphatidylethanolamine in rat liver plasma membrane.
Topics: Animals; Cell Membrane; Cyclic AMP; Guanosine Triphosphate; Isoproterenol; Kinetics; Liver; Male; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Theophylline | 1983 |
Alteration in the effect of GTP on cerebral beta-adrenergic receptor binding during morphine withdrawal.
Topics: Animals; Dihydroalprenolol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Kinetics; Male; Morphine Dependence; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Subcellular Fractions; Substance Withdrawal Syndrome | 1983 |
A second guanyl nucleotide-binding site associated with adenylate cyclase. Distinct nucleotides activate adenylate cyclase and permit ADP-ribosylation by cholera toxin.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cholera Toxin; Columbidae; Cytosol; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Nucleoside Diphosphate Sugars; Receptors, Cell Surface; Thionucleotides | 1983 |
The activity of adenylate cyclase and phosphodiesterase in the isoproterenol-damaged cardiac muscle of spontaneously hypertensive rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Cardiomyopathies; Cell Membrane; Cyclic AMP; Guanosine Triphosphate; Hypertension; Isoproterenol; Male; Myocardium; Rats | 1983 |
Trapping of the beta-adrenergic receptor in the hormone-induced state.
Topics: Animals; Deoxycholic Acid; Erythrocyte Membrane; GTP-Binding Proteins; Guanosine Triphosphate; Hydrogen-Ion Concentration; Isoproterenol; Protein Binding; Protein Conformation; Receptors, Adrenergic, beta; Receptors, Cell Surface; Turkeys | 1983 |
Studies on cyclic nucleotides in the adrenal gland. XI. Adrenergic regulation of adenylate cyclase activity in the adrenal cortex.
Topics: Adenylyl Cyclases; Adrenal Cortex; Adrenocorticotropic Hormone; Albuterol; Animals; Cell Membrane; Dihydroalprenolol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1984 |
Effect of gentamicin treatment on adenylate cyclase and Na+, K+-ATPase activities in renal tissues of rats.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Gentamicins; Guanosine Triphosphate; Isoproterenol; Kidney; Kidney Cortex; Kidney Glomerulus; Male; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1983 |
Forskolin stimulates adenylate cyclase activity, adenosine 3',5'-monophosphate production and peptide release from the intermediate lobe of the rat pituitary gland.
Topics: Adenylyl Cyclases; Animals; Antihypertensive Agents; Apomorphine; Colforsin; Cyclic AMP; Diterpenes; Guanosine Triphosphate; Isoproterenol; Kinetics; Melanocyte-Stimulating Hormones; Pituitary Gland; Rats | 1984 |
Beta-adrenergic regulation of Sertoli cell adenylyl cyclase: desensitization by homologous hormone.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Fluorides; Follicle Stimulating Hormone; Guanosine Triphosphate; Isoproterenol; Kinetics; Male; Rats; Receptors, Adrenergic, beta; Sertoli Cells | 1984 |
Induction of catecholamine-responsive adenylate cyclase in HeLa cells by sodium butyrate. Evidence for a more efficient stimulatory regulatory component.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alprostadil; Butyrates; Butyric Acid; Cholera Toxin; Enzyme Induction; Guanosine Triphosphate; Guanylyl Imidodiphosphate; HeLa Cells; Humans; Isoproterenol; Kinetics; Prostaglandins E; Receptors, Adrenergic, beta; Sodium Fluoride | 1984 |
Characteristics of the adenylate cyclase system of differentiating rabbit bone marrow erythroblasts.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Bone Marrow; Cell Differentiation; Cyclic AMP; Erythroblasts; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Membrane Proteins; Phosphorylation; Propranolol; Rabbits | 1983 |
Developmental alterations in guanine nucleotide regulation of the beta-adrenergic receptor-adenylate cyclase system of skeletal muscle.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Cyclic AMP; Dihydroalprenolol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Muscle Development; Muscles; Rabbits; Receptors, Adrenergic, beta; Sodium Fluoride | 1984 |
[Calcium-dependent regulation of cardiac adenyl cyclase by calmodulin].
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Magnesium; Myocardium; Rabbits; Receptors, Cell Surface; Sarcolemma; Sodium Fluoride | 1984 |
Dynamics of the lymphocyte beta-adrenoceptor system in patients with allergic bronchial asthma.
Topics: Adenylyl Cyclases; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Cell Membrane; Dihydroalprenolol; Female; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Isoproterenol; Lymphocytes; Male; Propranolol; Receptors, Adrenergic, beta; Respiratory Hypersensitivity | 1984 |
Regulation of hormone-responsive Sertoli cell adenylyl cyclase in a cell-free system.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell-Free System; Cells, Cultured; Follicle Stimulating Hormone; Guanosine Triphosphate; Isoproterenol; Kinetics; Magnesium; Male; Rats; Rats, Inbred Strains; Sertoli Cells; Time Factors | 1984 |
Partial purification of a water-soluble liver protein that regulates adenylate cyclase activity (basal, hormone- and cholera-toxin-activated) and cholera-toxin-catalyzed ADP-ribosylation of the membrane G protein.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cholera Toxin; Cytosol; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Liver; Nucleoside Diphosphate Sugars; Proteins; Rats | 1984 |
Adenylate cyclase activity in crude plasma membranes of subcutaneous adipocytes during ontogenetic development of rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Aging; Animals; Cell Membrane; Cosyntropin; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Rats; Rats, Inbred Strains; Sodium Fluoride | 1982 |
Calmodulin activates adenylate cyclase from rabbit heart plasma membranes.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Cell Fractionation; Enzyme Activation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Myocardium; Rabbits; Sarcolemma | 1984 |
Ontogenesis of physiological responsiveness and guanine nucleotide sensitivity of cardiac muscarinic receptors during chick embryonic development.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Atrial Function; Bacterial Toxins; Carbachol; Chick Embryo; Depression, Chemical; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; Heart Rate; Isoproterenol; Myocardium; Pertussis Toxin; Quinuclidinyl Benzilate; Receptors, Muscarinic; Virulence Factors, Bordetella | 1984 |
Catecholamine and divalent cation effects on frog liver adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Calcium; Catecholamines; Cations, Divalent; Epinephrine; Female; Guanosine Triphosphate; Isoproterenol; Liver; Magnesium; Male; Manganese; Propranolol; Rana pipiens; Sodium Fluoride | 1983 |
CRF stimulates adenylate cyclase activity in the intermediate lobe of the pituitary gland.
Topics: Adenylyl Cyclases; Animals; Cattle; Corticotropin-Releasing Hormone; Guanosine Triphosphate; Isoproterenol; Pituitary Gland | 1983 |
Forskolin-activated adenylate cyclase. Inhibition by guanyl-5'-yl imidodiphosphate.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Colforsin; Diterpenes; Enzyme Activation; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Magnesium; Male; Manganese; Rats; Rats, Inbred Strains | 1983 |
Pertussis toxin reverses Gpp(NH)p inhibition of basal and forskolin activated adipocyte adenylate cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Bacterial Toxins; Colforsin; Diterpenes; Enzyme Activation; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Pertussis Toxin; Rabbits; Rats; Rats, Inbred Strains; Time Factors; Virulence Factors, Bordetella | 1983 |
Effects of 9-beta-D-arabinofuranosyl-guanine-5'-triphosphate on adenylate cyclase: comparison with GTP and GPP(NH)P.
Topics: Adenylyl Cyclases; Adipose Tissue; Adipose Tissue, Brown; Alprostadil; Animals; Arabinonucleotides; Chickens; Cricetinae; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Mesocricetus; Myocardium; Oxotremorine; Prostaglandins E | 1983 |
Halothane inhibition of canine myocardial adenylate cyclase--modulation by endogenous factors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Culture Media; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Guanosine Triphosphate; Halothane; In Vitro Techniques; Intracellular Membranes; Isoproterenol; Myocardium; Sarcolemma | 1984 |
The effect of anions and cations on cardiac adenylate cyclase: interactions with isoprenaline and GTP.
Topics: Acetates; Adenylyl Cyclases; Animals; Anions; Cations; Chlorides; Enzyme Activation; Guanosine Triphosphate; Isoproterenol; Kinetics; Male; Myocardium; Phosphates; Rabbits; Sarcolemma | 1984 |
Properties of gonadotropin-stimulable adenylyl cyclase of the human corpus luteum: regulation of hormonal responsiveness by guanyl nucleotide and magnesium ion.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adult; Chorionic Gonadotropin; Corpus Luteum; Enzyme Activation; Female; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Kinetics; Magnesium; Prostaglandins E | 1984 |
Cholera toxin activation of adenylate cyclase. Roles of nucleoside triphosphates and a macromolecular factor in the ADP ribosylation of the GTP-dependent regulatory component.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cholera Toxin; Columbidae; Cytosol; Edetic Acid; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Molecular Weight; Nucleoside Diphosphate Sugars; Ribonucleotides | 1980 |
Characteristics of the beta-adrenergic adenylate cyclase system of developing rabbit bone-marrow erythroblasts.
Topics: Adenylyl Cyclases; Animals; Bone Marrow; Cell Differentiation; Dose-Response Relationship, Drug; Erythroblasts; Erythrocytes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Kinetics; Male; Pindolol; Rabbits | 1983 |
Adenylate cyclase activity of circular and longitudinal muscle layers of rat myometrium.
Topics: Adenylyl Cyclases; Animals; Female; Guanosine Triphosphate; Isoproterenol; Myometrium; Rats; Rats, Inbred Strains; Uterus | 1983 |
Catalytic unit of adenylate cyclase: reduced activity in aged-human lymphocytes.
Topics: Adenylyl Cyclases; Adult; Aged; Aging; Colforsin; Diterpenes; Enzyme Activation; Guanosine Triphosphate; Humans; Isoproterenol; Lymphocytes; Male; Sodium Fluoride | 1982 |
The role of Mg2+ in hormone stimulation of rat osteosarcoma adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cattle; Cell Line; Dose-Response Relationship, Drug; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Magnesium; Osteosarcoma; Parathyroid Hormone; Rats | 1981 |
Preparation of hormone-sensitive airway smooth muscle adenylate cyclase from dissociated canine trachealis cells.
Topics: Adenylyl Cyclases; Animals; Dinoprostone; Dogs; Enzyme Activation; Epinephrine; Guanosine Triphosphate; Hormones; Isoproterenol; Kinetics; Muscle, Smooth; Norepinephrine; Propranolol; Prostaglandins E; Sodium Fluoride; Trachea | 1981 |
Specific inhibition by Na+ of TSH-stimulated thyroid cell adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Dinoprostone; Guanosine Triphosphate; Isoproterenol; Prostaglandins E; Sodium; Swine; Thyroid Gland; Thyrotropin | 1982 |
Guanyl nucleotides participate in the beta-adrenergic stimulation of adenylate cyclase activity in the intermediate lobe of the rat pituitary gland.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Sodium Fluoride | 1982 |
D-2 dopamine receptor-mediated inhibition of adenylate cyclase activity in the intermediate lobe of the rat pituitary gland requires guanosine 5'-triphosphate.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Cholera Toxin; Dopamine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1982 |
Characteristics of hormone-stimulated adenylate cyclase in vascular smooth muscle: altered activity in spontaneously hypertensive rat.
Topics: Adenylyl Cyclases; Animals; Aorta; Dose-Response Relationship, Drug; Guanosine Triphosphate; Hypertension; Isoproterenol; Muscle, Smooth, Vascular; Propranolol; Rats; Rats, Inbred Strains; Sacrococcygeal Region | 1982 |
Kinetics and thermodynamics of activation of pretreatment with guanosine 5'-[beta, gamma-imido]triphosphate of smooth-muscle adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Enzyme Activation; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Kinetics; Muscle, Smooth; Rats; Temperature; Thermodynamics | 1982 |
Secretin and VIP-stimulated adenylate cyclase from rat heart. I. General properties and structural requirements for enzyme activation.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Gastrointestinal Hormones; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Magnesium; Male; Myocardium; Rats; Secretin; Structure-Activity Relationship; Vasoactive Intestinal Peptide | 1980 |
[Effects of GTP and NaF on rabbit heart adenylate cyclase activated by guanyl-5'-ilimidodiphosphate].
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Enzyme Activation; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Myocardium; Rabbits; Sodium Fluoride | 1980 |
Effects of prostaglandin E2 on adenylate cyclase activity and lipolysis in human adipose tissue.
Topics: Adenylyl Cyclases; Adipose Tissue; Dose-Response Relationship, Drug; Female; Guanosine Triphosphate; Humans; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Prostaglandins E | 1981 |
Prostaglandins increase GTP hydrolysis by membranes from human mononuclear cells.
Topics: Animals; Cell Membrane; Erythrocyte Membrane; Erythrocytes; Guanosine Triphosphate; Humans; Hydrolysis; Isoproterenol; Kinetics; Monocytes; Platelet Aggregation; Prostaglandins; Prostaglandins E | 1980 |
Modulation of adenylate cyclase in intact macrophages by microtubules. Opposing actions of colchicine and chemotactic factor.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colchicine; Fluorides; Guanosine Triphosphate; Guinea Pigs; Isoproterenol; Macrophages; Male; Methionine; Microtubules; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Prostaglandins E; Vinblastine | 1980 |
On the mode of action of catecholamines on the turkey erythrocyte adenylyl cyclase. Evaluation of basic activity states after removal of endogenous GDP and interpretation of nucleotide regulation and hormone activation in terms of a two-state model.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Erythrocyte Membrane; Erythrocytes; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Models, Biological; Turkeys | 1980 |
Characterization of the dopamine-responsive adenylate cyclase of bovine parathyroid cells and its relationship to parathyroid hormone secretion.
Topics: Adenylyl Cyclases; Animals; Cattle; Dopamine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Kinetics; Parathyroid Glands; Parathyroid Hormone; Sodium Fluoride | 1980 |
Beta 3-adrenergic activation of adenylyl cyclase in mouse white adipocytes: modulation by GTP and effect of obesity.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Albuterol; Analysis of Variance; Animals; Cell Membrane; Dioxoles; DNA Probes; DNA, Complementary; Enzyme Activation; Epididymis; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Kinetics; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Propranolol; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Thinness; Virulence Factors, Bordetella | 1995 |
GTP requirement for isoproterenol activation of calcium channels in vascular myocytes.
Topics: Animals; Calcium Channels; Colforsin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Male; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Rabbits; Thionucleotides | 1995 |
Characteristics of the alpha 2/beta 2-adrenergic receptor-coupled adenylyl cyclase system in rat myometrium during pregnancy.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Base Sequence; Cell Membrane; Clonidine; DNA Primers; Female; Gene Expression; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Male; Molecular Sequence Data; Myometrium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; RNA, Messenger; Signal Transduction; Virulence Factors, Bordetella; Yohimbine | 1995 |
Bovine hereditary cardiomyopathy: an animal model of human dilated cardiomyopathy.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cardiomyopathies; Cardiomyopathy, Dilated; Catecholamines; Cattle; Cattle Diseases; Colforsin; Disease Models, Animal; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; Heart Atria; Heart Ventricles; Humans; Isoproterenol; Manganese; Myocardial Contraction; Myocardium; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Reference Values; Sodium Fluoride; Ventricular Function, Right; Virulence Factors, Bordetella | 1995 |
m-Acetylanilido-GTP, a novel photoaffinity label for GTP-binding proteins: synthesis and application.
Topics: Adenylyl Cyclases; Affinity Labels; Animals; Enzyme Activation; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Immunosorbent Techniques; Isoproterenol; Photochemistry; Propranolol; Turkeys | 1995 |
Beta-adrenergic agonists regulate KCa channels in airway smooth muscle by cAMP-dependent and -independent mechanisms.
Topics: Adenylyl Imidodiphosphate; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Horses; Ion Channel Gating; Isoproterenol; Kinetics; Membrane Potentials; Muscle, Smooth; Potassium Channels; Trachea | 1994 |
A cytosolic peptide potentiates the GTP effect on beta-adrenergic response of adenylate cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding, Competitive; Cytosol; Dihydroalprenolol; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Guanosine Triphosphate; Isoproterenol; Peptides; Rats; Rats, Wistar | 1994 |
Pertussis toxin blocks M2 muscarinic receptor-mediated effects on contraction and cyclic AMP in the guinea pig ileum, but not M3-mediated contractions and phosphoinositide hydrolysis.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Cyclic AMP; Guanosine Triphosphate; Guinea Pigs; Hydrolysis; Ileum; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; N-Methylscopolamine; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Signal Transduction; Virulence Factors, Bordetella | 1994 |
Isoproterenol modulates the calcium channels through two different mechanisms in smooth-muscle cells from rabbit portal vein.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calcium Channels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine Triphosphate; Ion Channel Gating; Isoproterenol; Isoquinolines; Male; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Piperazines; Portal Vein; Protein Kinase Inhibitors; Rabbits; Signal Transduction | 1994 |
Beta-adrenergic receptor overexpression in the fetal rat: distribution, receptor subtypes, and coupling to adenylate cyclase activity via G-proteins.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Autoradiography; Fetus; Fluorides; Gene Expression Regulation, Developmental; Gestational Age; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tissue Distribution | 1994 |
ADP-ribosylation of Gs by cholera toxin is potentiated by agonist activation of beta-adrenergic receptors in the absence of GTP.
Topics: Adenosine Diphosphate Ribose; Adrenergic beta-Agonists; Alprenolol; Catalysis; Cell Line; Cholera Toxin; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Isoproterenol; Receptors, Adrenergic, beta | 1993 |
Effects of hydrogen peroxide on stimulatory guanine nucleotide-binding protein in rat heart.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Colforsin; Cyclic AMP; Dihydroalprenolol; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; Hydrogen Peroxide; In Vitro Techniques; Isoproterenol; Lymphoma; Male; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1993 |
Hormone-induced rise in cytosolic Ca2+ in axolotl hepatocytes: extracellular origin and control by cAMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Ambystoma mexicanum; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Epinephrine; Glucagon; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Liver; Phentolamine; Propranolol; Thionucleotides; Vasotocin | 1993 |
Estrogen uncouples beta-adrenergic receptor from the stimulatory guanine nucleotide-binding protein in female rat hypothalamus.
Topics: Adenylyl Cyclases; Animals; Colforsin; Enzyme Activation; Estradiol; Female; GTP-Binding Proteins; Guanosine Triphosphate; Hypothalamus; Isoproterenol; Ovariectomy; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Uncoupling Agents | 1993 |
Regulation of Ca2+ current in frog ventricular cardiomyocytes by guanosine 5'-triphosphate analogues and isoproterenol.
Topics: Acetylcholine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; In Vitro Techniques; Isoproterenol; Myocardium; Rana catesbeiana | 1993 |
Analysis of receptor-stimulated and basal guanine nucleotide binding to membrane G proteins by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Topics: Adenylyl Imidodiphosphate; Animals; Autoradiography; Binding, Competitive; Brain; Cell Membrane; Dopamine; Electrophoresis, Polyacrylamide Gel; Fluphenazine; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Isoproterenol; Kinetics; Phosphoproteins; Phosphorus Radioisotopes; Propranolol; Rats; Receptors, Adrenergic, alpha; Receptors, Dopamine | 1993 |
Measurement of both cyclic [3H]AMP and cyclic [3H]GMP in cultured vascular smooth muscle cells labeled with [3H]hypoxanthine: use in studies of cardiovascular drugs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Triphosphate; Animals; Cardiovascular Agents; Cells, Cultured; Cyclic AMP; Cyclic GMP; Drug Evaluation, Preclinical; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Isoproterenol; Isotope Labeling; Muscle, Smooth, Vascular; Nitroprusside; Radioimmunoassay; Rats; Rats, Inbred WKY; Reproducibility of Results; Tritium | 1993 |
Conditional activation of cAMP signal transduction by protein kinase C. The effect of phorbol esters on adenylyl cyclase in permeabilized and intact cells.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Guanosine Triphosphate; Isoproterenol; Mice; Molecular Sequence Data; Phorbol Esters; Protein Kinase C; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction | 1994 |
Adenylate cyclase activity in microdissected rat liver tissue: periportal to pericentral activity gradient.
Topics: Adenylyl Cyclases; Angiotensin II; Animals; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Lithium; Lithium Chloride; Liver; Male; Rats; Rats, Sprague-Dawley; Sodium Fluoride | 1993 |
Isoproterenol and GTP gamma S inhibit L-type calcium channels of differentiating rat skeletal muscle cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Cell Differentiation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Ion Channel Gating; Isoproterenol; Muscles; Pertussis Toxin; Photolysis; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Thionucleotides; Virulence Factors, Bordetella | 1993 |
Epidermal growth factor and isoproterenol stimulation of the Ras-guanine nucleotide exchange factor in proliferating rat parotid gland acinar cells.
Topics: Animals; Cell Division; Epidermal Growth Factor; Eukaryotic Initiation Factor-2; Female; Guanine Nucleotide Exchange Factors; Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Oncogene Protein p21(ras); Parotid Gland; Proteins; ras Guanine Nucleotide Exchange Factors; Rats; Rats, Sprague-Dawley; Signal Transduction | 1993 |
Receptor-induced heterologous desensitization of receptor-regulated phospholipase C.
Topics: Animals; Dose-Response Relationship, Drug; Erythrocytes; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Receptors, Purinergic; Signal Transduction; Time Factors; Turkeys; Type C Phospholipases | 1995 |
Adrenergic desensitization in left ventricle from streptozotocin diabetic swine.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aluminum; Animals; Blood Glucose; Colforsin; Cyclic AMP; Cytosol; Diabetes Mellitus, Experimental; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Heart Ventricles; Insulin; Isoproterenol; Receptors, Adrenergic, beta; Sarcolemma; Signal Transduction; Streptozocin; Swine; Swine, Miniature | 1995 |
Beta-adrenoceptor desensitization despite cardiac denervation in human failing transplanted myocardium.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Biopsy; Colforsin; Denervation; GTP-Binding Proteins; Guanosine Triphosphate; Heart Transplantation; Heart Ventricles; Humans; Isoproterenol; Ventricular Function, Left | 1996 |
Beta-adrenoceptor control of cardiac adenylyl cyclase during development: agonist pretreatment in the neonate uniquely causes heterologous sensitization, not desensitization.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Female; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Male; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1995 |
Temporal effects of cytokines on neonatal cardiac myocyte Ca2+ transients and adenylate cyclase activity.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Animals, Newborn; Calcium; Cells, Cultured; Colforsin; Guanosine Triphosphate; Heart; Heart Ventricles; Interleukin-1; Isoproterenol; Kinetics; Myocardial Contraction; Myocardium; Rats; Time Factors; Tumor Necrosis Factor-alpha | 1997 |
Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Animals, Newborn; Body Weight; Carbachol; Cell Membrane; Colforsin; Drug Hypersensitivity; Female; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Heart; Isoproterenol; Male; Manganese; Membrane Proteins; Muscarinic Agonists; Myocardium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Time Factors | 1997 |
Conditional activation defect of a human Gsalpha mutant.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Arginine; Cell Line; Conserved Sequence; Cyclic AMP; Glutamic Acid; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Isoproterenol; Kinetics; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Spodoptera; Transfection | 1997 |
Receptor-independent activation of cardiac adenylyl cyclase by GDP and membrane-associated nucleoside diphosphate kinase. A new cardiotonic mechanism?
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Dogs; Enzyme Activation; Enzyme Inhibitors; Guanosine Diphosphate; Guanosine Triphosphate; Heart; In Vitro Techniques; Isoproterenol; Myocardium; Nucleoside-Diphosphate Kinase; Receptors, Cell Surface; Sarcolemma; Thionucleotides; Uridine Diphosphate | 1997 |
Right ventricular infundibular beta-adrenoceptor complex in tetralogy of Fallot patients.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Child; Child, Preschool; Colforsin; Female; Guanosine Triphosphate; Heart Ventricles; Humans; Hypoxia; Imidazoles; In Vitro Techniques; Infant; Isoproterenol; Male; Myocardium; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sodium Fluoride; Tetralogy of Fallot | 1997 |
Chronic carbachol pretreatment decreases adenylyl cyclase activity in airway smooth muscle.
Topics: Adenylyl Cyclases; Animals; Atropine; Carbachol; Cattle; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Kinetics; Muscle, Smooth; Protein Kinase C; Receptor, Muscarinic M3; Receptors, Muscarinic; Staurosporine; Trachea | 1997 |
Ontogenic development of the adenylyl cyclase enzyme and the alpha s, alpha i1 and alpha i2 G-protein regulatory subunits from rat prostate.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Blotting, Northern; Colforsin; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Prostate; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Testosterone; Transcription, Genetic; Vasoactive Intestinal Peptide | 1997 |
Molecular diversity of adenylyl cyclases in human and rat myometrium. Correlation with global adenylyl cyclase activity during mid- and term pregnancy.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Dose-Response Relationship, Drug; Female; Guanosine Triphosphate; Humans; Isoproterenol; Myometrium; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Rats; Rats, Sprague-Dawley; Sympathomimetics; Transducin | 1997 |
Mutations at the domain interface of GSalpha impair receptor-mediated activation by altering receptor and guanine nucleotide binding.
Topics: Adenylyl Cyclases; Aluminum Compounds; Binding, Competitive; Enzyme Activation; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Iodocyanopindolol; Isoproterenol; Models, Molecular; Mutation; Pindolol; Protein Binding; Protein Structure, Secondary; Receptors, Adrenergic, beta; Transfection; Tumor Cells, Cultured | 1998 |
Biological evaluation of a lipid-mobilizing factor isolated from the urine of cancer patients.
Topics: Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Animals; Body Composition; Cachexia; Cells, Cultured; Cyclic AMP; Digestive System Neoplasms; Drinking; Eating; Female; Glycoproteins; Guanosine Triphosphate; Humans; Isoproterenol; Lipid Mobilization; Lipolysis; Male; Mice; Mice, Inbred Strains; Mice, Obese; Omentum; Ovarian Neoplasms; Peptides; Seminal Plasma Proteins; Zn-Alpha-2-Glycoprotein | 1998 |
Molecular mechanisms of adenylyl cyclase desensitization in pregnant rat myometrium following in vivo administration of the beta-adrenergic agonist, isoproterenol.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colforsin; Drug Tolerance; Female; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Myometrium; Pindolol; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA, Messenger | 1998 |
Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Anti-Inflammatory Agents; Cerebellum; Colforsin; Dexamethasone; Fluorides; Glucocorticoids; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Kidney; Male; Manganese; Rats; Rats, Sprague-Dawley; Signal Transduction | 1998 |
Contribution of serine residues to constitutive and agonist-induced signaling via the D2S dopamine receptor: evidence for multiple, agonist-specific active conformations.
Topics: Animals; Cyclic AMP; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Mutagenesis; Oocytes; Potassium Channels; Protein Conformation; Rats; Receptors, Dopamine D2; Serine; Signal Transduction; Sulfur Radioisotopes; Tumor Cells, Cultured; Xenopus laevis | 1998 |
Reconstitution of beta2-adrenoceptor-GTP-binding-protein interaction in Sf9 cells--high coupling efficiency in a beta2-adrenoceptor-G(s alpha) fusion protein.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; beta-Adrenergic Receptor Kinases; Binding, Competitive; Cell Line; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; Dihydroalprenolol; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Kinetics; Polymerase Chain Reaction; Propanolamines; Rats; Receptors, Adrenergic, beta; Recombinant Fusion Proteins; Spodoptera; Transfection | 1998 |
Developmental enhancement of secretory response to isoproterenol coupled with increases in beta-adrenoceptor density and Gs protein function in rat parotid tissues.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Culture Techniques; Female; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Male; Organ Size; Parotid Gland; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Muscarinic | 1998 |
Chronic oxytocin pretreatment inhibits adenylyl cyclase activity in cultured rat myometrial cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Chlorides; Colforsin; Enzyme Inhibitors; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Isoproterenol; Manganese Compounds; Myometrium; Oxytocin; Pertussis Toxin; Phenylephrine; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Fluoride; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
Overexpression of Gi-proteins precedes the development of DOCA-salt-induced hypertension: relationship with adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Autoradiography; Blotting, Northern; Colforsin; Desoxycorticosterone; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypertension; Immunoblotting; Isoproterenol; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sarcolemma; Sodium Chloride; Time Factors | 1998 |
Effects of guanine, inosine, and xanthine nucleotides on beta(2)-adrenergic receptor/G(s) interactions: evidence for multiple receptor conformations.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cell Membrane; Cells, Cultured; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gs; Guanosine Triphosphate; Hydrolysis; Inosine Triphosphatase; Inosine Triphosphate; Insecta; Isoproterenol; Kinetics; Ligands; Propanolamines; Protein Binding; Protein Conformation; Purine Nucleotides; Pyrophosphatases; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Ribonucleotides | 1999 |
Sympathetic potentiation of cyclic ADP-ribose formation in rat cardiac myocytes.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; CHO Cells; Cholera Toxin; Chromatography, Thin Layer; Cricetinae; Cyclic ADP-Ribose; Guanosine Triphosphate; Heart; Isoproterenol; Membrane Glycoproteins; Myocardium; NAD+ Nucleosidase; Rats; Rats, Wistar; Spectrometry, Fluorescence; Sympathetic Nervous System | 1999 |
Membrane-bound form of ADP-ribosyl cyclase in rat cortical astrocytes in culture.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Astrocytes; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Cerebral Cortex; Fluorometry; Guanosine Triphosphate; Isoproterenol; Membrane Glycoproteins; NAD+ Nucleosidase; Rats; Rats, Wistar; Subcellular Fractions | 2000 |
Differential alterations in cardiac adrenergic signaling in chronic hypoxia or norepinephrine infusion.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cholera Toxin; Chronic Disease; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Heart Rate; Heart Ventricles; Hypertrophy, Left Ventricular; Hypertrophy, Right Ventricular; Hypoxia; Isoproterenol; Male; Myocardium; Norepinephrine; Pertussis Toxin; Propanolamines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Signal Transduction; Sodium Fluoride; Sympathomimetics; Tritium; Virulence Factors, Bordetella; Weight Gain | 2001 |
G protein signaling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway.
Topics: Amino Acid Sequence; Animals; beta Catenin; Cloning, Molecular; Cytoskeletal Proteins; Embryo, Nonmammalian; Endoderm; Frizzled Receptors; Gene Expression Regulation; Genes, Reporter; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Isoproterenol; Mice; Molecular Sequence Data; Pertussis Toxin; Propranolol; Proto-Oncogene Proteins; Receptors, Adrenergic, beta-2; Receptors, G-Protein-Coupled; Receptors, Neurotransmitter; Recombinant Fusion Proteins; Signal Transduction; Trans-Activators; Transcription Factors; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella; Wnt Proteins; Xenopus; Xenopus Proteins; Zebrafish Proteins | 2001 |
The olfactory G protein G(alphaolf) possesses a lower GDP-affinity and deactivates more rapidly than G(salphashort): consequences for receptor-coupling and adenylyl cyclase activation.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Alternative Splicing; Animals; Cell Line; Cell Membrane; Dihydroalprenolol; Dobutamine; Ephedrine; Genetic Variation; GTP-Binding Protein alpha Subunits; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Isoproterenol; Kinetics; Rats; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Recombinant Proteins; Spodoptera; Transfection | 2001 |
Maturation of rat brain is accompanied by differential expression of the long and short splice variants of G(s)alpha protein: identification of cytosolic forms of G(s)alpha.
Topics: Adenylyl Cyclases; Alternative Splicing; Animals; Brain; Brain Chemistry; Cell Membrane; Cerebral Cortex; Cytosol; Electrophoresis, Polyacrylamide Gel; Gene Expression; GTP-Binding Protein alpha Subunits, Gs; Guanosine Triphosphate; Hippocampus; Immunoblotting; Isoproterenol; Male; Ouabain; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Thalamus; Tritium | 2001 |
Cross talk between beta-adrenergic and bradykinin B(2) receptors results in cooperative regulation of cyclic AMP accumulation and mitogen-activated protein kinase activity.
Topics: Affinity Labels; Animals; Azides; COS Cells; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Enzyme Activation; ErbB Receptors; Guanosine Triphosphate; Immunohistochemistry; Isoproterenol; MAP Kinase Signaling System; Models, Biological; Phosphatidylinositols; Phosphorylation; Protein Binding; Receptors, Adrenergic, beta; Receptors, Bradykinin; Time Factors; Transcriptional Activation; Transfection; Tyrosine | 2001 |
Real-time visualization of a fluorescent G(alpha)(s): dissociation of the activated G protein from plasma membrane.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Cholera Toxin; Computer Systems; COS Cells; Enzyme Activation; Green Fluorescent Proteins; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Isoproterenol; Luminescent Proteins; Lymphoma; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Transfection; Tumor Cells, Cultured | 2002 |
Distinct interactions of G(salpha-long), G(salpha-short), and G(alphaolf) with GTP, ITP, and XTP.
Topics: Adenylyl Cyclases; Alternative Splicing; Animals; Cell Membrane; Cells, Cultured; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Hydrogen Bonding; Inosine Triphosphate; Insecta; Isoproterenol; Kinetics; Recombinant Fusion Proteins; Ribonucleotides; Transfection | 2002 |
Pertussis toxin-insensitive activation of the heterotrimeric G-proteins Gi/Go by the NG108-15 G-protein activator.
Topics: Animals; Brain; Carrier Proteins; Cattle; Cell Line; Cell Membrane; Colforsin; Glioma; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Isoproterenol; NAD; Neuroblastoma; Pertussis Toxin; Phosphorus Radioisotopes; Tumor Cells, Cultured | 2002 |
[The hormone-sensitive adenylyl cyclase system of the ciliate Dileptus anser].
Topics: Adenylyl Cyclases; Animals; Ciliophora; Enzyme Activation; Epinephrine; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Protein Synthesis Inhibitors; Serotonin; Structure-Activity Relationship | 2002 |
Amygdaloid D1 receptors are not linked to stimulation of adenylate cyclase.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Amygdala; Animals; Benzazepines; Binding Sites; Brain Chemistry; Calmodulin; Caudate Nucleus; Cell Membrane; Colforsin; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Fenoldopam; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Microdissection; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Sulfur Isotopes; Tissue Distribution | 2003 |
Phospholipase C, but not InsP3 or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Animals; Aristolochic Acids; Bridged-Ring Compounds; Caffeine; Calcium; Carbachol; Diglycerides; Estrenes; Guanosine Triphosphate; Guinea Pigs; Ileum; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoenzymes; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth; Norbornanes; Patch-Clamp Techniques; Phospholipase C beta; Phospholipases A; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Ryanodine; Thiocarbamates; Thiones; Type C Phospholipases | 2004 |
[Molecular mechanisms of regulatory action of adrenergic receptor agonists on functional activity of adenylyl cyclase signaling system of the ciliates Dileptus anser and Tetrahymena pyriformis].
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cell Membrane; Ciliophora; Dihydroalprenolol; Enzyme Activation; Epinephrine; Guanosine Triphosphate; Isoproterenol; Signal Transduction; Tetrahymena pyriformis | 2004 |
Phosphorylation of P-Rex1 by the cyclic AMP-dependent protein kinase inhibits the phosphatidylinositiol (3,4,5)-trisphosphate and Gbetagamma-mediated regulation of its activity.
Topics: Animals; Cell Line; Chemotaxis; Cyclic AMP-Dependent Protein Kinases; Dimerization; Gene Expression Regulation, Enzymologic; Glutathione Transferase; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Humans; Immunoprecipitation; Insecta; Isoproterenol; Mass Spectrometry; Phosphatidylinositols; Phosphorylation; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Recombinant Proteins | 2006 |
Pregnancy and estradiol modulate myometrial G-protein pathways in the guinea pig.
Topics: Adrenergic beta-Agonists; Animals; Blotting, Western; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Estradiol; Female; Gene Expression Profiling; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Isoproterenol; Myometrium; Pregnancy; Protein Biosynthesis; Signal Transduction; Up-Regulation; Uterine Contraction | 2006 |
Functional adenylyl cyclase inhibition in murine cardiomyocytes by 2'(3')-O-(N-methylanthraniloyl)-guanosine 5'-[gamma-thio]triphosphate.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanosine Triphosphate; Isoproterenol; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; ortho-Aminobenzoates | 2007 |
Changed sensitivity of adenylate cyclase signaling system to biogenic amines and peptide hormones in tissues of starving rats.
Topics: Adenylyl Cyclases; Animals; Biogenic Amines; Brain; Bromocriptine; Colforsin; Guanosine Triphosphate; Heart; Isoproterenol; Male; Muscle, Skeletal; Myocardium; Rats; Rats, Wistar; Serotonin; Signal Transduction; Somatostatin; Starvation | 2007 |
Functional coupling of hormone receptors with G proteins in the adenylate cyclase system of the rat muscle tissues and brain under conditions of short-term hyperglycemia.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Brain; Cells; Cyclic AMP; Diabetes Mellitus, Type 1; GTP-Binding Proteins; Guanosine Triphosphate; Hyperglycemia; In Vitro Techniques; Isoproterenol; Male; Muscle, Skeletal; Protein Binding; Rats; Rats, Wistar; Receptors, Peptide; Relaxin; Somatostatin; Streptozocin | 2007 |
Characterization of mouse heart adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Catalysis; Cations, Divalent; Cell Line; Cell Membrane; Colforsin; Enzyme Inhibitors; Female; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoenzymes; Isoproterenol; Kinetics; Metoprolol; Mice; Mice, Inbred Strains; Myocardium; Protein Isoforms; Receptors, G-Protein-Coupled; Recombinant Proteins; Spodoptera | 2009 |
Involvement of β-adrenergic receptor in synaptic vesicle swelling and implication in neurotransmitter release.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Aquaporin 6; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Immunoblotting; Immunoprecipitation; Isoproterenol; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Neurotransmitter Agents; Peptides; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Synaptic Vesicles; Synaptosomes; Wasp Venoms | 2011 |
Arf6 negatively controls the rapid recycling of the β2 adrenergic receptor.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Adrenergic beta-2 Receptor Agonists; Animals; Arrestins; beta-Arrestins; Biocatalysis; Cattle; Cell Compartmentation; Cell Membrane; Endocytosis; Endosomes; Green Fluorescent Proteins; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; HEK293 Cells; Humans; Isoproterenol; Ligands; Lysosomes; Models, Biological; Nerve Tissue Proteins; Protein Binding; Protein Transport; rab4 GTP-Binding Proteins; Receptors, Adrenergic, beta-2 | 2012 |
Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound β
Topics: Animals; Binding Sites; Cattle; Cell Line; GTP-Binding Protein alpha Subunits, Gs; Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Models, Molecular; Protein Binding; Protein Domains; Protein Structure, Secondary; Receptors, Adrenergic, beta-1 | 2020 |