isoproterenol has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 132 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 33 (25.00) | 18.7374 |
1990's | 80 (60.61) | 18.2507 |
2000's | 18 (13.64) | 29.6817 |
2010's | 1 (0.76) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Coraboeuf, E; Couétil, JP; Deroubaix, E; Le Grand, B | 1 |
Denton, RM; Rutter, GA | 1 |
Felbel, J; Hofmann, F; Peper, K; Welling, A | 2 |
Freeman, LC; Kass, RS; Kwok, WM | 1 |
Insel, PA; Jasper, JR; Leiber, D; Ransnäs, LA | 1 |
Barber, DL; Ganz, MB | 1 |
Downes, CP; Vaziri, C | 1 |
Gadsby, DC; Horie, M; Hwang, TC; Nairn, AC | 1 |
Graziano, MP; Kotlikoff, MI; Kume, H | 1 |
Spiess, J; Weik, R | 1 |
Balasubramaniam, A; Sheriff, S | 1 |
Garrison, JC; Liang, MN | 1 |
Hamada, E; Kurachi, Y; Shimada, T; Sugimoto, T; Terano, A | 1 |
Morad, M; Sorbera, LA | 1 |
Day, R; Farnsworth, CL; Feig, LA; Hildebrandt, JD | 1 |
Freissmuth, M; Marullo, S; Schütz, W; Selzer, E; Strosberg, AD | 1 |
Hager, R; Rooney, TA; Thomas, AP | 1 |
Kilgour, E; Larner, J; Luttrell, L; Romero, G | 1 |
Audigier, Y; Bockaert, J; Journot, L; Pantaloni, C | 1 |
Houslay, MD; Milligan, G; Palmer, T; Strassheim, D | 1 |
Bruno, GR; Datta, SC; Robertson, PL | 1 |
Brown, AM; Kirsch, GE; Schubert, B; Vandongen, AM | 2 |
Ramos-Franco, J; Stefani, E; Toro, L | 1 |
Giles, W; Irisawa, H; Nakajima, T; Wu, S | 1 |
Giles, W; Irisawa, H; Nakajima, T | 1 |
Brand, JG; Kare, MR; Katz, Y; Naim, M | 1 |
Bulargina, TV; Popov, KM; Severin, ES | 1 |
Birnbaumer, L; Brown, AM; Codina, J; Imoto, Y; Reeves, JP; Yatani, A | 1 |
de Mazancourt, P; Giot, J; Giudicelli, Y; Lacasa, D | 1 |
Birnbaumer, L; Brown, AM; Codina, J; Imoto, Y; Mattera, R; Yatani, A | 1 |
Audigier, Y; Bockaert, J; Journot, L | 1 |
Burke, DN; Fleming, N; Sliwinski-Lis, E | 1 |
Iijima, T; Taira, N | 1 |
Bode, DC; Molinoff, PB | 1 |
Resek, JF; Ruoho, AE | 1 |
Benovic, JL; Birnbaumer, L; Caron, MG; Cerione, RA; Codina, J; Gierschik, P; Lefkowitz, RJ; Somers, R; Spiegel, AM; Staniszewski, C | 1 |
Kirilovsky, J; Schramm, M; Selinger, Z; Steiner-Mordoch, S | 1 |
Bilargina, TV; Popov, KM; Severin, ES | 1 |
Kassis, S | 1 |
Birnbaumer, L; Caron, MG; Cerione, RA; Codina, J; Gierschik, P; Lefkowitz, RJ; Somers, RL; Spiegel, AM; Staniszewski, C | 1 |
Anand-Srivastava, MB; Cantin, M | 1 |
Anand-Srivastava, MB; Cantin, M; Srivastava, AK | 1 |
Katada, T; Murakami, T; Yasuda, H | 1 |
Cooney, D; Dees, C; Hekman, M; Holzhöfer, A; Keenan, AK | 1 |
Boege, F; Cooney, D; Hekman, M; Helmreich, EJ; Jürss, R; Keenan, AK | 1 |
Casey, PJ; Gilman, AG; Graziano, MP | 1 |
Insel, PA; Ransnäs, LA | 1 |
Kaplan, RS; Rasenick, MM | 1 |
Gierschik, P; Spiegel, AM | 1 |
Anand-Srivastava, MB; Cantin, M; Johnson, RA; Picard, S | 1 |
Johnson, GL; Kelleher, DJ; Pessin, JE; Ruoho, AE | 1 |
Asano, T; Brandt, DR; Pedersen, SE; Ross, EM | 1 |
Asano, T; Pedersen, SE; Ross, EM; Scott, CW | 1 |
Asano, T; Ross, EM | 1 |
Aktories, K; Jakobs, KH; Minuth, M | 1 |
Asano, T; Gilman, AG; Katada, T; Ross, EM | 1 |
Bourne, HR; Brickman, AS; Brothers, VM; Farfel, Z; Kaslow, HR | 1 |
Gill, DM; Meren, R | 1 |
Koumi, S; Ten Eick, RE; Wasserstrom, JA | 1 |
Imai, A; Nashida, T; Shimomura, H | 1 |
Cox, RH; Shi, QY | 1 |
Anand-Srivastava, MB; de Champlain, J; Savoie, P | 1 |
Otomo, S; Tsuchida, K; Watajima, H | 1 |
Chorev, M; Halifa, I; Kleinhaus, S; Selinger, Z; Zor, T | 1 |
Hall, IP; Kotlikoff, MI; Kume, H; Takagi, K; Washabau, RJ | 1 |
Friedman, E; Wang, HY | 1 |
Downes, CP; James, SR; Milligan, G; Vaziri, C; Walker, TR | 1 |
Goodstadt, LJ; Kozlowski, RZ; Powell, T; Twist, VW | 1 |
Eto, K; Masaki, T; Ono, K; Ozaki, Y; Sakamoto, A; Satake, M; Tsujimoto, G | 1 |
Levine, MA; Martin, CS; McCaul, ME; Waltman, C; Wand, GS; Wolfgang, D | 1 |
Alousi, AA; Bernstein, D; Insel, PA; Jasper, JR; Leiber, D; Martin, J | 1 |
Bolton, TB; Imaizumi, Y; Muraki, K; Watanabe, M | 1 |
Böhm, M; Erdmann, E; Gierschik, P; Schwinger, RH; Uhlmann, R | 1 |
Cannon, B; Nedergaard, J; Svoboda, P; Unelius, L | 1 |
Satoh, H; Sperelakis, N | 2 |
Hartzell, HC; Parsons, TD | 1 |
Audigier, Y; Bockaert, J; Nebout, I; Pantaloni, C; van der Neut, R | 1 |
Andexinger, S; Caron, MG; Daniel, K; Lefkowitz, RJ; Lohse, MJ; Pippig, S; Puzicha, M | 1 |
Fischmeister, R; Frace, AM; Hartzell, HC; Méry, PF | 1 |
Cortinovis, C; Klimek, F; Nogueira, E | 1 |
Somasundaram, B; Tregear, RT | 1 |
Bilezikian, JP; Camacho, JA; Chen, G; Glusman, J; Morris, SA; Rohde, S | 1 |
Diehl, AM; Levine, MA; Samy, S; Wand, GS; Wolfgang, D | 1 |
Bazin, R; Charon, C; Diot-Dupuy, F; Emorine, LJ; Krief, S; Strosberg, AD | 1 |
Arthur, G; Badiani, K | 1 |
Cipris, S; Daniel, EE; Pasyk, EA | 1 |
Burford, NT; Nahorski, SR | 1 |
Baker, SP; Belardinelli, L; Ruble, J; Scammells, PJ; Shryock, JC; Srinivas, M | 1 |
el Hadri, K; Fève, B; Pairault, J | 1 |
Amano, I; Eguchi, T; Ishida, H; Ishikawa, Y | 1 |
Adomeit, A; Boehmer, A; Boehmer, FD; Graness, A; Kovalenko, M; Liebmann, C; Nürnberg, B; Steinmetzer, T; Wetzker, R | 1 |
Itoh, Y; Kimura, K; Oka, M; Shimidzu, T; Ukai, Y; Yoshikuni, Y | 1 |
Bourne, HR; Farfel, Z; Iiri, T | 1 |
Hammond, HK; Insel, PA; Ping, P | 1 |
Abdel-Latif, AA; Akhtar, RA; Ding, KH; Husain, S; Isales, CM | 1 |
Beindl, W; Böing, B; Freissmuth, M; Hohenegger, M; Kreimeyer, A; Nanoff, C; Nickel, P; Waldhoer, M | 1 |
Aksentsev, SL; Hamet, P; Orlov, SN; Pokudin, NI; Tremblay, J | 1 |
Nelson, CS; Neve, KA; Wiens, BL | 1 |
Kobilka, BK; Lam, VT; Lee, TW; Seifert, R | 1 |
Adamson, P; Bozó, B; Deli, MA; Fábián, G; Greenwood, J; Joó, F; Krizbai, IA; Szabó, CA; Szucs, M | 1 |
Anand-Srivastava, MB; de Champlain, J; Marcil, J | 1 |
Kume, H; Takagi, K | 1 |
Warner, DR; Weinstein, LS | 1 |
Maekawa, M; Miyazaki, H; Murayama, T; Narita, H; Nomura, Y; Ono, S | 1 |
Anand-Srivastava, MB; Ge, C; Palaparti, A | 1 |
Garnier, V; Tillement, JP; Zini, R | 1 |
Baranski, TJ; Bourne, HR; Iiri, T; Lichtarge, O; Meng, EC; Nissenson, RA; Sheikh, SP; Vilardarga, JP | 1 |
McDonald, TF; Shuba, LM | 1 |
Guan, X; Kobilka, BK; Lee, TW; Seifert, R | 1 |
Anand-Srivastava, MB; Garcia, R; Ge, C | 2 |
Kather, H; Krieger-Brauer, HI; Medda, PK; Sattel, B | 1 |
Defer, N; Esposito, G; Garel, MC; Hajar, I; Hanoune, J; Lipskaia, L; Rockman, HA | 1 |
Anand-Srivastava, MB; Di Fusco, F; Hashim, S | 1 |
Liu, HY; Seifert, R; Wenzel-Seifert, K | 1 |
Kohout, TA; Lefkowitz, RJ; Mao, L; McDonald, PH; Perry, SJ; Rockman, HA; Takaoka, H | 1 |
Adli, H; Bazin, R; Diot-Dupuy, F; Ferré, P; Mory, G; Wiel, M | 1 |
Berul, CI; Gehrmann, J; Hammer, PE; Maguire, CT; Martins, DC; Meister, M; Mende, U; Neer, EJ | 1 |
Arthur, JM; Jose, PO; Kobilka, BK; Seifert, R; Wenzel-Seifert, K | 1 |
Hildebrandt, JD; Lanier, SM; Ribas, C; Sato, M; Takesono, A | 1 |
Denson, DD; Eaton, DC; Li, J; Wang, X | 1 |
Anand-Srivastava, MB; Hashim, S; Li, Y | 1 |
Anand-Srivastava, MB; Daou, GB; Lappas, G | 1 |
Fu, W; Harris, KH; Hawkes, C; Jhamandas, JH; Kar, S; MacDonald, RG | 1 |
Hayashi, M; Jones, KA; Nakayama, T; Penheiter, AR; Penheiter, SG; Warner, DO | 1 |
Advenier, C; Bardou, M; Breuiller-Fouché, M; Cecchi, R; Croci, T; Descamps, L; Fradin, Y; Germain, G; Guagnini, F; Leroy, MJ; Marini, P; Pascal, M; Rouget, C; Viviani, N | 1 |
Bowman, MR; Chen, H; Deng, B; Goldman, S; Kasaian, M; Macleod, C; Mason, L; Williams, C; Wolf, S | 1 |
Geduhn, J; Gille, A; Göttle, M; Höcherl, K; König, B; Seifert, R | 1 |
Baamonde, C; Dierssen, M; Flórez, J; Martínez-Cué, C | 1 |
2 review(s) available for isoproterenol and guanosine 5'-o-(3-thiotriphosphate)
Article | Year |
---|---|
Direct G-protein regulation of Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cattle; Dihydropyridines; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Humans; Isoproterenol; Thionucleotides | 1989 |
Reconstitution of the regulatory functions of beta-adrenergic receptors.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Chemical Phenomena; Chemistry; Erythrocyte Membrane; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hormones; In Vitro Techniques; Isoproterenol; Kinetics; Liposomes; Models, Biological; Phospholipids; Pindolol; Propranolol; Rats; Receptors, Adrenergic, beta; Synaptic Transmission; Thermodynamics; Thionucleotides | 1984 |
130 other study(ies) available for isoproterenol and guanosine 5'-o-(3-thiotriphosphate)
Article | Year |
---|---|
Effects of atrionatriuretic factor on Ca2+ current and Cai-independent transient outward K+ current in human atrial cells.
Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Calcium; Calcium Channels; Dialysis; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heart Atria; Humans; In Vitro Techniques; Isoproterenol; Membrane Potentials; Middle Aged; Myocardium; Potassium Channels | 1992 |
Effects of insulin and guanosine 5'-[gamma-thio]triphosphate on fatty acid synthesis and lipolysis within electropermeabilized fat-cells.
Topics: Adipose Tissue; Animals; Biological Transport; Cell Membrane Permeability; Electric Stimulation; Fatty Acids; Glucose; Guanosine 5'-O-(3-Thiotriphosphate); Insulin; Isoproterenol; Kinetics; Lipolysis; Male; Phosphoric Diester Hydrolases; Rats; Rats, Inbred Strains; Triglycerides | 1992 |
Hormonal regulation of calcium current in freshly isolated airway smooth muscle cells.
Topics: Albuterol; Animals; Calcium Channels; Cattle; Cesium; Chlorides; Cyclic AMP; Egtazic Acid; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hormones; In Vitro Techniques; Isoproterenol; Muscle, Smooth; Nitrendipine; Phentolamine; Potassium Chloride; Prazosin; Propranolol; Tetraethylammonium; Tetraethylammonium Compounds; Thionucleotides; Trachea | 1992 |
Phosphorylation-independent regulation of cardiac IK by guanine nucleotides and isoproterenol.
Topics: Animals; Cyclic AMP; Electrophysiology; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Myocardium; Phosphorylation; Potassium Channels; Thionucleotides | 1992 |
Beta-adrenergic-receptor-mediated dissociation and membrane release of the Gs protein in S49 lymphoma-cell membranes. Dependence on Mg2+ and GTP.
Topics: Animals; Cell Line; Cell Membrane; Enzyme-Linked Immunosorbent Assay; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Kinetics; Lymphoma; Macromolecular Substances; Magnesium; Mice; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1992 |
Guanine nucleotides regulate beta-adrenergic activation of Na-H exchange independently of receptor coupling to Gs.
Topics: Amiloride; Animals; Carrier Proteins; Cells, Cultured; Cricetinae; Dogs; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen-Ion Concentration; Ileum; Intestinal Mucosa; Isoproterenol; Kinetics; L Cells; Meglumine; Mice; Propranolol; Receptors, Adrenergic, beta; Sodium; Sodium Fluoride; Sodium-Hydrogen Exchangers; Thionucleotides; Transfection | 1992 |
G-protein-mediated activation of turkey erythrocyte phospholipase C by beta-adrenergic and P2y-purinergic receptors.
Topics: Adenosine; Adenosine Diphosphate; Adrenergic beta-Antagonists; Animals; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Inositol; Isoproterenol; Kinetics; Phosphatidylinositols; Propranolol; Receptors, Adrenergic, beta; Receptors, Purinergic; Thionucleotides; Turkeys; Type C Phospholipases | 1992 |
Role of GTP-binding proteins in the regulation of mammalian cardiac chloride conductance.
Topics: Acetylcholine; Adenylate Cyclase Toxin; Adrenergic beta-Agonists; Animals; Carbachol; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Heart; Histamine; Ion Channels; Isoproterenol; Membrane Proteins; Myocardium; Pertussis Toxin; Phosphorylation; Propranolol; Receptors, Adrenergic, beta; Receptors, Muscarinic; Time Factors; Virulence Factors, Bordetella | 1992 |
Stimulatory and inhibitory regulation of calcium-activated potassium channels by guanine nucleotide-binding proteins.
Topics: Adenylate Cyclase Toxin; Animals; Calcium; Cells, Cultured; Dogs; Ferrets; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Membrane Potentials; Muscle, Smooth; Pertussis Toxin; Potassium Channels; Swine; Thionucleotides; Trachea; Virulence Factors, Bordetella | 1992 |
Isoproterenol enhances a calcium-independent potassium current in mouse anterior pituitary tumor cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cholera Toxin; Epinephrine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Mice; Pertussis Toxin; Pituitary Gland, Anterior; Pituitary Neoplasms; Potassium Channels; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Inhibitory and stimulatory effects of neuropeptide Y(17-36) on rat cardiac adenylate cyclase activity. Structure-function studies.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cholera Toxin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heart Ventricles; Isoproterenol; Neuropeptide Y; Peptide Fragments; Pertussis Toxin; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Virulence Factors, Bordetella | 1992 |
The epidermal growth factor receptor is coupled to a pertussis toxin-sensitive guanine nucleotide regulatory protein in rat hepatocytes.
Topics: Animals; Binding Sites; Calcium; Carcinoma, Squamous Cell; Cell Membrane; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Isoproterenol; Kinetics; Liver; Male; Pertussis Toxin; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1991 |
Beta-angonists modulate ACh-inhibition of a K current in intestinal smooth muscle cells.
Topics: Acetylcholine; Animals; Bucladesine; Cell Membrane; Electric Conductivity; Female; Guanosine 5'-O-(3-Thiotriphosphate); Ileum; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth; Potassium Channels; Propranolol; Rabbits | 1991 |
Modulation of cardiac sodium channels by cAMP receptors on the myocyte surface.
Topics: Animals; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guinea Pigs; Heart; Isoproterenol; Kinetics; Membrane Potentials; Pertussis Toxin; Rana pipiens; Rats; Receptors, Cyclic AMP; Sodium Channels; Thionucleotides; Virulence Factors, Bordetella | 1991 |
A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors.
Topics: Adenylyl Cyclases; Animals; Asparagine; Binding Sites; Blotting, Northern; Cyclic AMP; Enzyme Activation; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Magnesium; Mice; Mutation; Oncogene Protein p21(ras); Serine; Tumor Cells, Cultured | 1991 |
Expression of two human beta-adrenergic receptors in Escherichia coli: functional interaction with two forms of the stimulatory G protein.
Topics: Cell Membrane; Cloning, Molecular; Escherichia coli; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Kinetics; Pindolol; Receptors, Adrenergic, beta; Recombinant Proteins | 1991 |
Beta-adrenergic receptor-mediated phospholipase C activation independent of cAMP formation in turkey erythrocyte membranes.
Topics: Adrenergic beta-Antagonists; Animals; Cyclic AMP; Enzyme Activation; Erythrocyte Membrane; Guanosine 5'-O-(3-Thiotriphosphate); Inositol Phosphates; Isoproterenol; Kinetics; Receptors, Adrenergic, beta; Turkeys; Type C Phospholipases | 1991 |
A pertussis toxin-sensitive G-protein mediates some aspects of insulin action in BC3H-1 murine myocytes.
Topics: Animals; Cell Line; Cell Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Insulin; Isoproterenol; Kinetics; Macromolecular Substances; Mice; Muscles; Pertussis Toxin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptor, Insulin; Signal Transduction; Tyrosine; Virulence Factors, Bordetella | 1990 |
Beta-adrenergic receptor stimulates L-type calcium current in adult smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium Channels; Cattle; Cyclic AMP; Dialysis; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Isoproterenol; Membrane Potentials; Muscle, Smooth; Protein Kinases; Receptors, Adrenergic, beta; Thionucleotides; Trachea | 1991 |
Deletion within the amino-terminal region of Gs alpha impairs its ability to interact with beta gamma subunits and to activate adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Cholera Toxin; DNA Mutational Analysis; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoproterenol; Macromolecular Substances; Mice; Peptide Fragments; Receptors, Adrenergic, beta; Recombinant Proteins; Signal Transduction; Structure-Activity Relationship; Trypsin | 1991 |
Alterations in G-protein expression and the hormonal regulation of adenylate cyclase in the adipocytes of obese (fa/fa) Zucker rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Macromolecular Substances; Male; Obesity; Rats; Rats, Zucker; Secretin; Thyrotropin | 1991 |
Glutamate-stimulated, guanine nucleotide-mediated phosphoinositide turnover in astrocytes is inhibited by cyclic AMP.
Topics: Animals; Astrocytes; Bucladesine; Calcium; Cyclic AMP; Digitonin; Drug Combinations; Glutamates; Glutamic Acid; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Isoproterenol; Phosphatidylinositols; Thionucleotides | 1990 |
Inhibition of cardiac Na+ currents by isoproterenol.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Magnesium; Myocardium; Sodium Channels; Thionucleotides | 1990 |
GTP-dependent regulation of myometrial KCa channels incorporated into lipid bilayers.
Topics: Adenosine Triphosphate; Animals; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Lipid Bilayers; Magnesium; Myometrium; Norepinephrine; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sympathomimetics; Thionucleotides | 1990 |
Mechanism of acetylcholine-induced inhibition of Ca current in bullfrog atrial myocytes.
Topics: Acetylcholine; Action Potentials; Adenylyl Cyclase Inhibitors; Animals; Calcium; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heart Atria; In Vitro Techniques; Isoproterenol; Myocardium; Rana catesbeiana; Receptors, Adrenergic, beta; Receptors, Muscarinic | 1990 |
N-ethylmaleimide uncouples muscarinic receptors from acetylcholine-sensitive potassium channels in bullfrog atrium.
Topics: Acetylcholine; Animals; Calcium Channels; Cyclic AMP; Ethylmaleimide; Guanosine 5'-O-(3-Thiotriphosphate); Heart Atria; In Vitro Techniques; Isoproterenol; Myocardium; Potassium Channels; Rana catesbeiana; Receptors, Muscarinic | 1990 |
Nonreceptor-mediated responses of adenylate cyclase in membranes from liver, muscle, and white and brown adipose tissue of obese (fa/fa) and lean (Fa/) Zucker rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Adipose Tissue, Brown; Animals; Body Weight; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Liver; Muscles; Norepinephrine; Obesity; Organ Size; Rats; Rats, Zucker; Receptors, Adrenergic, beta | 1990 |
Factors essential for desensitization of pigeon erythrocyte adenylate cyclase responsiveness in a cell-free system.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Binding, Competitive; Cell-Free System; Columbidae; Cyclic AMP; Cytosol; Drug Tolerance; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Protein Kinases; Thionucleotides | 1985 |
A G protein directly regulates mammalian cardiac calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; Ion Channels; Isoproterenol; Leupeptins; Membrane Potentials; Phosphorylation; Thionucleotides; Ventricular Function | 1987 |
Role of adenosine 3',5'-monophosphate and the Ri-receptor Gi-coupled adenylate cyclase inhibitory pathway in the mechanism whereby adrenalectomy increases the adenosine antilipolytic effect in rat fat cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Adrenalectomy; Animals; Bucladesine; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Lipolysis; Male; Manganese; Niacin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Thionucleotides | 1989 |
Reconstitution of cyc- S49 membranes by in vitro translated Gs alpha. Membrane anchorage and functional implications.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Isoproterenol; Lymphoma; Mice; Molecular Weight; Mutation; NAD; Osmolar Concentration; Protein Biosynthesis; RNA, Messenger; Thionucleotides; Tumor Cells, Cultured | 1989 |
G regulatory proteins and muscarinic receptor signal transduction in mucous acini of rat submandibular gland.
Topics: Adenylate Cyclase Toxin; Animals; Calcium; Carbachol; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoproterenol; Kinetics; Mucous Membrane; Pertussis Toxin; Phosphatidylinositols; Rats; Receptors, Muscarinic; Signal Transduction; Submandibular Gland; Thionucleotides; Virulence Factors, Bordetella | 1989 |
Beta-adrenergic inhibition of cardiac sodium channels by dual G-protein pathways.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heart; Isoproterenol; Potassium Channels; Rats; Receptors, Adrenergic, beta; Signal Transduction; Sodium Channels; Thionucleotides | 1989 |
Mechanisms of beta-adrenoceptor mediated increase in delayed rectifier potassium current.
Topics: Animals; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Membrane Potentials; Potassium; Receptors, Adrenergic, beta; Second Messenger Systems; Thionucleotides; Ventricular Function | 1989 |
Effects of ethanol in vitro on the beta adrenergic receptor-coupled adenylate cyclase system.
Topics: Adenylyl Cyclases; Animals; Cell Line; Dose-Response Relationship, Drug; Ethanol; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Lymphoma; Molecular Weight; Propranolol; Receptors, Adrenergic, beta; Thionucleotides | 1988 |
Photoaffinity labeling the beta-adrenergic receptor with an iodoazido derivative of norepinephrine.
Topics: Adenylyl Cyclases; Affinity Labels; Alprenolol; Animals; Azides; Binding, Competitive; Cell Membrane; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Indicators and Reagents; Isoproterenol; Kinetics; Lung; Magnesium; Norepinephrine; Receptors, Adrenergic, beta; Thionucleotides | 1988 |
Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles.
Topics: Adenylyl Cyclases; Animals; Erythrocytes; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Humans; Isoproterenol; Kinetics; Liposomes; Lung; Membrane Proteins; Phosphatidylcholines; Receptors, Adrenergic, beta; Retina; Retinal Pigments; Rhodopsin; Thionucleotides; Transducin | 1985 |
Lipid requirements for reconstitution of the delipidated beta-adrenergic receptor and the regulatory protein.
Topics: Animals; Erythrocyte Membrane; Glycine max; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Magnesium; Magnesium Chloride; Membrane Lipids; Phospholipids; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1985 |
[Heterologous desensitization of pigeon erythrocyte adenylate cyclase by the catalytic subunit of cAMP-dependent protein kinase].
Topics: Adenylyl Cyclases; Animals; Columbidae; Erythrocyte Membrane; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Macromolecular Substances; Phosphorylation; Protein Kinases; Receptors, Adrenergic, beta; Thionucleotides | 1985 |
Modulation of the receptor-coupled adenylate cyclase system in HeLa cells by sodium butyrate.
Topics: Adenylyl Cyclases; Butyrates; Butyric Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; HeLa Cells; Humans; Isoproterenol; Kinetics; Receptors, Adrenergic, beta; Thionucleotides | 1985 |
Mechanism of guanine nucleotide regulatory protein-mediated inhibition of adenylate cyclase. Studies with isolated subunits of transducin in a reconstituted system.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cattle; Cricetinae; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Humans; Isoproterenol; Liposomes; Macromolecular Substances; Magnesium; Magnesium Chloride; Membrane Proteins; Receptors, Adrenergic, beta; Thionucleotides; Transducin | 1986 |
Atrial natriuretic factor receptors are negatively coupled to adenylate cyclase in cultured atrial and ventricular cardiocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Animals, Newborn; Cells, Cultured; Colforsin; Dopamine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart Atria; Heart Ventricles; Isoproterenol; Myocardium; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thionucleotides | 1986 |
Pertussis toxin attenuates atrial natriuretic factor-mediated inhibition of adenylate cyclase. Involvement of inhibitory guanine nucleotide regulatory protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Aorta; Atrial Natriuretic Factor; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Male; Molecular Weight; NAD; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thionucleotides; Virulence Factors, Bordetella | 1987 |
Reduction in the activity of the stimulatory guanine nucleotide-binding protein in the myocardium of spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypertension; Isoproterenol; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic, beta; Sarcolemma; Thionucleotides | 1987 |
Unimpaired coupling of phosphorylated, desensitized beta-adrenoceptor to Gs in a reconstitution system.
Topics: Adenylyl Cyclases; Animals; Colforsin; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Phosphorylation; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1987 |
Functional and structural characterization of the two beta 1-adrenoceptor forms in turkey erythrocytes with molecular masses of 50 and 40 kilodaltons.
Topics: Animals; Chromatography, Affinity; Erythrocyte Membrane; Glycoside Hydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Iodocyanopindolol; Isoproterenol; Kinetics; Molecular Weight; Pindolol; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1987 |
Expression of cDNAs for G proteins in Escherichia coli. Two forms of Gs alpha stimulate adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Brain Chemistry; Cattle; Centrifugation, Density Gradient; Cholera Toxin; Chromatography; DNA; DNA-Directed RNA Polymerases; DNA, Recombinant; Escherichia coli; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Plasmids; T-Phages; Thionucleotides; Transformation, Genetic | 1987 |
Subunit dissociation is the mechanism for hormonal activation of the Gs protein in native membranes.
Topics: Animals; Cell Line; Cell Membrane; Enzyme-Linked Immunosorbent Assay; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Liver; Lymphoma; Macromolecular Substances; Rabbits; Thionucleotides | 1988 |
Guanine nucleotide activation of adenylate cyclase in saponin permeabilized glioma cells.
Topics: Adenylyl Cyclases; Cell Line; Cell Membrane Permeability; Enzyme Activation; Glioma; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Saponins; Thionucleotides | 1986 |
Chymotrypsin selectively decreases forskolin stimulation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Chymotrypsin; Colforsin; Erythrocyte Membrane; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Thionucleotides; Turkeys | 1985 |
Ninhibin: a sperm factor attenuates the atrial natriuretic factor mediated inhibition of adenylate cyclase: possible involvement of inhibitory guanine nucleotide regulatory protein.
Topics: Acrosin; Adenylyl Cyclase Inhibitors; Animals; Aorta; Cattle; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Endopeptidases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Natriuretic Agents; Proteins; Rats; Thionucleotides | 1985 |
Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.
Topics: Adenylyl Cyclases; Animals; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Phorbols; Phosphorylation; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Thionucleotides; Time Factors; Turkeys | 1984 |
Reconstitution of catecholamine-stimulated binding of guanosine 5'-O-(3-thiotriphosphate) to the stimulatory GTP-binding protein of adenylate cyclase.
Topics: Animals; Drug Stability; Erythrocyte Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hot Temperature; Isoproterenol; Kinetics; Liposomes; Liver; Magnesium; Protein Binding; Protein Denaturation; Rabbits; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1984 |
Catecholamine-stimulated guanosine 5'-O-(3-thiotriphosphate) binding to the stimulatory GTP-binding protein of adenylate cyclase: kinetic analysis in reconstituted phospholipid vesicles.
Topics: Animals; Dose-Response Relationship, Drug; Erythrocyte Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Liposomes; Liver; Magnesium; Protein Binding; Rabbits; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1984 |
Sodium regulation of hormone-sensitive adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Alprostadil; Animals; Blood Platelets; Cricetinae; Cyclic AMP; Epinephrine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; In Vitro Techniques; Isoproterenol; Lymphoma; Prostaglandins E; Receptors, Adrenergic, beta; Receptors, Cell Surface; Sodium Chloride; Thionucleotides | 1984 |
Activation of the inhibitory GTP-binding protein of adenylate cyclase, Gi, by beta-adrenergic receptors in reconstituted phospholipid vesicles.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bacterial Proteins; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Lipid Bilayers; Liver; NAD; Pertussis Toxin; Rabbits; Receptors, Adrenergic, beta; Receptors, Cell Surface; Thionucleotides; Virulence Factors, Bordetella | 1984 |
Human mutation affecting hormone-sensitive adenylate cyclase.
Topics: Adenylyl Cyclases; Cholera Toxin; Cyclic AMP; Erythrocyte Membrane; Erythrocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Isoproterenol; Mutation; Pseudohypoparathyroidism; Thionucleotides | 1981 |
A second guanyl nucleotide-binding site associated with adenylate cyclase. Distinct nucleotides activate adenylate cyclase and permit ADP-ribosylation by cholera toxin.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cholera Toxin; Columbidae; Cytosol; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Nucleoside Diphosphate Sugars; Receptors, Cell Surface; Thionucleotides | 1983 |
Beta-adrenergic and cholinergic modulation of inward rectifier K+ channel function and phosphorylation in guinea-pig ventricle.
Topics: Acetylcholine; Animals; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Ethers, Cyclic; Ganglia, Parasympathetic; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Okadaic Acid; Patch-Clamp Techniques; Pertussis Toxin; Phosphoprotein Phosphatases; Phosphorylation; Potassium Channels; Receptors, Adrenergic, beta; Sympathomimetics; Virulence Factors, Bordetella | 1995 |
Effect of PT-treatment on ANP-mediated inhibition of adenylate cyclase and amylase release in rat parotid gland.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amylases; Animals; Atrial Natriuretic Factor; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Male; Parotid Gland; Pertussis Toxin; Rats; Rats, Wistar; Receptors, Atrial Natriuretic Factor; Virulence Factors, Bordetella | 1994 |
GTP requirement for isoproterenol activation of calcium channels in vascular myocytes.
Topics: Animals; Calcium Channels; Colforsin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Male; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Rabbits; Thionucleotides | 1995 |
C-type natriuretic peptide and brain natriuretic peptide inhibit adenylyl cyclase activity: interaction with ANF-R2/ANP-C receptors.
Topics: Adenylyl Cyclase Inhibitors; Angiotensin II; Animals; Atrial Natriuretic Factor; Cell Membrane; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanylate Cyclase; Isoproterenol; Kinetics; Myocardium; Natriuretic Peptide, Brain; Natriuretic Peptide, C-Type; Nerve Tissue Proteins; Proteins; Rats; Receptors, Atrial Natriuretic Factor | 1995 |
Calcium current in rat diabetic ventricular myocytes.
Topics: Action Potentials; Animals; Blood Glucose; Body Weight; Calcium Channels; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Electric Conductivity; Guanosine 5'-O-(3-Thiotriphosphate); Heart; Heart Ventricles; Isoproterenol; Kinetics; Male; Myocardial Contraction; Rats; Rats, Wistar | 1994 |
m-Acetylanilido-GTP, a novel photoaffinity label for GTP-binding proteins: synthesis and application.
Topics: Adenylyl Cyclases; Affinity Labels; Animals; Enzyme Activation; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Immunosorbent Techniques; Isoproterenol; Photochemistry; Propranolol; Turkeys | 1995 |
Beta-adrenergic agonists regulate KCa channels in airway smooth muscle by cAMP-dependent and -independent mechanisms.
Topics: Adenylyl Imidodiphosphate; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Horses; Ion Channel Gating; Isoproterenol; Kinetics; Membrane Potentials; Muscle, Smooth; Potassium Channels; Trachea | 1994 |
Receptor-mediated activation of G proteins is reduced in postmortem brains from Alzheimer's disease patients.
Topics: Aged; Alzheimer Disease; Biotransformation; Brain Chemistry; Carbachol; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Immunoblotting; Isoproterenol; Male; Protein Binding; Receptors, Neurotransmitter; Sulfur Radioisotopes | 1994 |
The turkey erythrocyte beta-adrenergic receptor couples to both adenylate cyclase and phospholipase C via distinct G-protein alpha subunits.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Cyclic AMP; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Rats; Receptors, Adrenergic, beta; Signal Transduction; Thionucleotides; Turkeys; Type C Phospholipases | 1994 |
Modulation of cardiac L-type Ca2+ channels by GTP gamma S in response to isoprenaline, forskolin and photoreleased nucleotides.
Topics: Animals; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Heart; Isoproterenol; Myocardium; Photolysis; Protein Kinase Inhibitors; Thionucleotides | 1994 |
Endothelin-A receptor mediates cardiac inhibition by regulating calcium and potassium currents.
Topics: Action Potentials; Animals; Calcium; Cell Membrane; Cyclic AMP; Endothelins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardium; Potassium; Rabbits; Receptor, Endothelin A; Receptors, Endothelin | 1994 |
Differential expression of guanosine triphosphate binding proteins in men at high and low risk for the future development of alcoholism.
Topics: Adenosine Diphosphate Ribose; Adult; Alcoholism; Cell Membrane; Erythrocyte Membrane; Family; Fathers; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Immunoblotting; Isoproterenol; Kinetics; Lymphocytes; Male; Regression Analysis; Risk Factors | 1994 |
Alteration in Gs-mediated signal transduction in S49 lymphoma cells treated with inhibitors of microtubules.
Topics: Adenylyl Cyclases; Catalysis; Cholera Toxin; Colchicine; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Lymphoma; Microtubules; Signal Transduction; Somatostatin; Tumor Cells, Cultured; Vinblastine | 1993 |
Effect of isoprenaline on Ca2+ channel current in single smooth muscle cells isolated from taenia of the guinea-pig caecum.
Topics: Animals; Calcium Channels; Cecum; Cyclic AMP; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kinetics; Male; Membrane Potentials; Muscle, Smooth; Receptors, Adrenergic; Thionucleotides | 1993 |
Coupling of M-cholinoceptors and A1 adenosine receptors in human myocardium.
Topics: Atropine; Binding, Competitive; Carbachol; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heart; Heart Atria; Heart Ventricles; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Myocardial Contraction; Myocardium; Papillary Muscles; Phenylisopropyladenosine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Receptors, Purinergic P1; Theophylline | 1994 |
Attenuation of Gs alpha coupling efficiency in brown-adipose-tissue plasma membranes from cold-acclimated hamsters.
Topics: Acclimatization; Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Cell Fractionation; Cell Membrane; Cold Temperature; Cricetinae; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Isoproterenol; Mesocricetus; Ouabain; Sodium Fluoride | 1993 |
Hyperpolarization-activated inward current in embryonic chick cardiac myocytes: developmental changes and modulation by isoproterenol and carbachol.
Topics: Action Potentials; Animals; Carbachol; Cells, Cultured; Cesium; Chick Embryo; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Heart; Heart Rate; Heart Ventricles; Isoproterenol; Myocardium; Receptors, Adrenergic, beta; Temperature | 1993 |
Regulation of Ca2+ current in frog ventricular cardiomyocytes by guanosine 5'-triphosphate analogues and isoproterenol.
Topics: Acetylcholine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; In Vitro Techniques; Isoproterenol; Myocardium; Rana catesbeiana | 1993 |
Mutagenesis of the amino-terminal glycine to alanine in Gs alpha subunit alters beta gamma-dependent properties and decreases adenylylcyclase activation.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alanine; Animals; Base Sequence; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Cholera Toxin; Enzyme Activation; Glycine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Myristic Acid; Myristic Acids; Oligodeoxyribonucleotides; Plasmids; Polymerase Chain Reaction; Protein Biosynthesis; Protein Processing, Post-Translational; Receptors, Adrenergic, beta; RNA, Messenger; Transcription, Genetic | 1993 |
Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antibodies; Antigens; Arrestins; beta-Adrenergic Receptor Kinases; beta-Arrestins; Blotting, Western; Cell Line; CHO Cells; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Eye Proteins; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Kinetics; Magnesium Chloride; Molecular Sequence Data; Peptides; Phosphorus Radioisotopes; Pindolol; Protein Kinases; Receptors, Adrenergic, beta; Transfection | 1993 |
Rate-limiting steps in the beta-adrenergic stimulation of cardiac calcium current.
Topics: Acetylcholine; Animals; Calcium Channels; Colforsin; Cyclic AMP; Epinephrine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heart; Hot Temperature; In Vitro Techniques; Isoproterenol; Kinetics; Myocardium; Photolysis; Propranolol; Rana catesbeiana; Rana esculenta; Receptors, Adrenergic, beta; Sympathetic Nervous System | 1993 |
Adenylate cyclase activity in microdissected rat liver tissue: periportal to pericentral activity gradient.
Topics: Adenylyl Cyclases; Angiotensin II; Animals; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Lithium; Lithium Chloride; Liver; Male; Rats; Rats, Sprague-Dawley; Sodium Fluoride | 1993 |
Isoproterenol and GTP gamma S inhibit L-type calcium channels of differentiating rat skeletal muscle cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Cell Differentiation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Ion Channel Gating; Isoproterenol; Muscles; Pertussis Toxin; Photolysis; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Thionucleotides; Virulence Factors, Bordetella | 1993 |
Opposing influences of dexamethasone and retinoic acid on adenylate cyclase activity in ROS 17/2.8 cells.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Amino Acid Sequence; Blotting, Northern; Cell Membrane; Colforsin; Dexamethasone; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Isoproterenol; Molecular Sequence Data; Osteosarcoma; RNA, Messenger; Sodium Fluoride; Tretinoin; Tumor Cells, Cultured | 1993 |
Chronic ethanol treatment increases expression of inhibitory G-proteins and reduces adenylylcyclase activity in the central nervous system of two lines of ethanol-sensitive mice.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Brain; Cell Membrane; Cerebellum; Colforsin; Corticotropin-Releasing Hormone; Ethanol; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Mice; Mice, Mutant Strains; Pertussis Toxin; Signal Transduction; Virulence Factors, Bordetella | 1993 |
Early alterations in the brown adipose tissue adenylate cyclase system of pre-obese Zucker rat fa/fa pups: decreased G-proteins and beta 3-adrenoceptor activities.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Adrenergic beta-Antagonists; Animals; Animals, Suckling; Base Sequence; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Imidazoles; Isoproterenol; Male; Molecular Sequence Data; Norepinephrine; Obesity; Rats; Rats, Zucker; Receptors, Adrenergic, beta; RNA, Messenger | 1995 |
Evidence for receptor and G-protein regulation of a phosphatidylethanolamine-hydrolysing phospholipase A1 in guinea-pig heart microsomes: stimulation of phospholipase A1 activity by DL-isoprenaline and guanine nucleotides.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Butoxamine; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Microsomes; Myocardium; Phosphatidylethanolamines; Phospholipases A; Phospholipases A1; Propranolol; Receptors, Adrenergic, beta | 1995 |
A G protein, not cyclic AMP, mediates effects of VIP on the inwardly rectifying K+ channels in endothelial cells.
Topics: Animals; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Endothelium, Vascular; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Isoproterenol; Norepinephrine; Pertussis Toxin; Potassium Channels; Thionucleotides; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1996 |
Muscarinic m1 receptor-stimulated adenylate cyclase activity in Chinese hamster ovary cells is mediated by Gs alpha and is not a consequence of phosphoinositidase C activation.
Topics: Adenylyl Cyclases; Animals; Antibodies; Carbachol; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Muscarinic Agonists; Phosphoric Diester Hydrolases; Receptors, Muscarinic; Recombinant Proteins; Transfection | 1996 |
A novel irreversible antagonist of the A1-adenosine receptor.
Topics: Adenosine; Animals; Carbachol; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Kinetics; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Potassium Channels; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P1; Theophylline; Xanthines | 1996 |
Triiodothyronine regulates beta 3-adrenoceptor expression in 3T3-F442A differentiating adipocytes.
Topics: 3T3 Cells; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Antagonists; Animals; Base Sequence; Cell Differentiation; Cell Nucleus; Colforsin; Dactinomycin; DNA Primers; Gene Expression; Glycerolphosphate Dehydrogenase; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Kinetics; Mice; Molecular Sequence Data; Propanolamines; Protein Biosynthesis; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triiodothyronine | 1996 |
Regulation of phosphorylation of Gi2 alpha protein controls the secretory response to isoproterenol in rat parotid tissues.
Topics: Adenosine Diphosphate Ribose; Amylases; Animals; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Ethers, Cyclic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Male; Okadaic Acid; Parotid Gland; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Secretory Rate; Signal Transduction; Up-Regulation | 1996 |
Tyrosine phosphorylation of GSalpha and inhibition of bradykinin-induced activation of the cyclic AMP pathway in A431 cells by epidermal growth factor receptor.
Topics: Adenylyl Cyclases; Bradykinin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Humans; Isoproterenol; Oncogene Proteins; Phosphorylation; Serine; Threonine; Tumor Cells, Cultured; Tyrosine | 1996 |
Involvement of metabotropic glutamate receptors in Gi- and Gs-dependent modulation of adenylate cyclase activity induced by a novel cognition enhancer NS-105 in rat brain.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Alanine; Animals; Baclofen; Brimonidine Tartrate; Cell Membrane; Cerebral Cortex; Cholera Toxin; Cognition; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoproterenol; Kinetics; Male; Manganese; Pertussis Toxin; Piperidines; Proline; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Neurotransmitter; Virulence Factors, Bordetella; Yohimbine | 1997 |
Developmental changes and modulation through G-proteins of the hyperpolarization-activated inward current in embryonic chick heart.
Topics: Animals; Calcium Channels; Carbachol; Chick Embryo; Fetal Heart; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heart Rate; Isoproterenol; Time Factors | 1993 |
Conditional activation defect of a human Gsalpha mutant.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Arginine; Cell Line; Conserved Sequence; Cyclic AMP; Glutamic Acid; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Isoproterenol; Kinetics; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Spodoptera; Transfection | 1997 |
Cardiac G-protein receptor kinase activity: effect of a beta-adrenergic receptor antagonist.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aluminum Compounds; Animals; Binding, Competitive; Bisoprolol; Colforsin; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Myocardium; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, beta; Swine | 1998 |
Inhibition of muscarinic-stimulated polyphosphoinositide hydrolysis and Ca2+ mobilization in cat iris sphincter smooth muscle cells by cAMP-elevating agents.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Carbachol; Cats; Cell Fractionation; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Inositol 1,4,5-Trisphosphate; Iris; Isoproterenol; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphodiesterase Inhibitors; Phosphorylation; Pyrrolidinones; Ryanodine; Thapsigargin; Type C Phospholipases | 1997 |
Gsalpha-selective G protein antagonists.
Topics: Adenylyl Cyclases; Animals; Benzenesulfonates; Benzimidazoles; Escherichia coli; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Iodocyanopindolol; Isoproterenol; Oncogene Proteins; Pindolol; Rats; Receptors, Adrenergic, beta; Receptors, Angiotensin; Receptors, Purinergic P1; Recombinant Proteins; Saralasin | 1998 |
Na+/H+ exchange in vascular smooth muscle cells is controlled by GTP-binding proteins.
Topics: Aluminum Chloride; Aluminum Compounds; Amiloride; Animals; Aorta; Biological Transport; Calcium; Cell Membrane Permeability; Cells, Cultured; Chlorides; Cyclic AMP; Deferoxamine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hydrogen-Ion Concentration; Isoproterenol; Kinetics; Male; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Potassium; Rats; Rats, Inbred BN; Sodium; Sodium Fluoride; Thionucleotides | 1998 |
Contribution of serine residues to constitutive and agonist-induced signaling via the D2S dopamine receptor: evidence for multiple, agonist-specific active conformations.
Topics: Animals; Cyclic AMP; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Mutagenesis; Oocytes; Potassium Channels; Protein Conformation; Rats; Receptors, Dopamine D2; Serine; Signal Transduction; Sulfur Radioisotopes; Tumor Cells, Cultured; Xenopus laevis | 1998 |
Reconstitution of beta2-adrenoceptor-GTP-binding-protein interaction in Sf9 cells--high coupling efficiency in a beta2-adrenoceptor-G(s alpha) fusion protein.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; beta-Adrenergic Receptor Kinases; Binding, Competitive; Cell Line; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; Dihydroalprenolol; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Kinetics; Polymerase Chain Reaction; Propanolamines; Rats; Receptors, Adrenergic, beta; Recombinant Fusion Proteins; Spodoptera; Transfection | 1998 |
Expression of G-protein subtypes in cultured cerebral endothelial cells.
Topics: Animals; Blotting, Western; Bradykinin; Brain; Cell Line; Cell Membrane; Cells, Cultured; Endothelium, Vascular; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Isoproterenol; Rats; Receptors, Adrenergic, beta; Receptors, Bradykinin | 1998 |
Overexpression of Gi-proteins precedes the development of DOCA-salt-induced hypertension: relationship with adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Autoradiography; Blotting, Northern; Colforsin; Desoxycorticosterone; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypertension; Immunoblotting; Isoproterenol; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sarcolemma; Sodium Chloride; Time Factors | 1998 |
Inhibition of beta-adrenergic desensitization by KCa channels in human trachealis.
Topics: Adjuvants, Immunologic; Adrenergic beta-Agonists; Aged; Bronchoconstrictor Agents; Cholera Toxin; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Isoproterenol; Large-Conductance Calcium-Activated Potassium Channels; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle, Smooth; Peptides; Potassium Channels; Potassium Channels, Calcium-Activated; Receptors, Adrenergic, beta; Scorpion Venoms; Trachea | 1999 |
A mutation in the heterotrimeric stimulatory guanine nucleotide binding protein alpha-subunit with impaired receptor-mediated activation because of elevated GTPase activity.
Topics: Adenylyl Cyclases; Aluminum Compounds; Amino Acid Substitution; Animals; Arginine; Cattle; Cloning, Molecular; Escherichia coli; Fibrous Dysplasia, Polyostotic; Fluorides; Glutamine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Isoproterenol; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Structure, Secondary; Recombinant Proteins | 1999 |
Effects of T-588, a novel cognitive enhancer, on ADP-ribosylation of G(s alpha) by cholera toxin and cyclic AMP accumulation in rat cerebral cortex.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Binding Sites; Catalysis; Cerebral Cortex; Cholera Toxin; Cyclic AMP; Diethylamines; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Nootropic Agents; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Thiophenes; Virulence Factors, Bordetella | 1999 |
Angiotensin II enhances the expression of Gialpha in A10 cells (smooth muscle): relationship with adenylyl cyclase activity.
Topics: Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cell Line; Colforsin; Dactinomycin; Dose-Response Relationship, Drug; Drug Interactions; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Muscle, Smooth, Vascular; Peptide Fragments; Protein Kinase C; Rats; Staurosporine | 1999 |
A GppNHp-insensitivity factor modulates the activation of beta-adrenoceptor-coupled Gs protein in rat cortex and cerebellum.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytes; Cerebellum; Cerebral Cortex; Cholic Acids; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Kinetics; Propanolamines; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Synaptosomes | 1999 |
Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation.
Topics: Animals; Binding, Competitive; Evolution, Molecular; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Histidine; Humans; Isoproterenol; Models, Molecular; Mutation; Pindolol; Protein Engineering; Protein Structure, Secondary; Receptors, Adrenergic, beta-2; Receptors, Parathyroid Hormone; Rod Opsins; Secretin; Sequence Alignment; Signal Transduction; Zinc | 1999 |
Lack of involvement of G proteins in the activation of cardiac CFTR Cl- current by genistein.
Topics: Adenylate Cyclase Toxin; Animals; Calcium Channels; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guinea Pigs; Heart; Isoproterenol; Pertussis Toxin; Protein-Tyrosine Kinases; Sympathomimetics; Thionucleotides; Virulence Factors, Bordetella | 1999 |
Restricting the mobility of Gs alpha: impact on receptor and effector coupling.
Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Agonists; Animals; Cell Membrane; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Rats; Receptors, Adrenergic, beta-2; Receptors, Cell Surface; Receptors, Dopamine D1; Recombinant Fusion Proteins; Spodoptera | 1999 |
Altered expression of Gi-protein and adenylyl cyclase activity in hearts from one kidney one clip hypertensive rats: effect of captopril.
Topics: Adenylyl Cyclases; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colforsin; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension, Renovascular; Isoproterenol; Myocardium; Rats; Rats, Sprague-Dawley | 1999 |
Inhibitory effect of isoproterenol on NADPH-dependent H(2)O(2) generation in human adipocyte plasma membranes is mediated by betagamma-subunits derived from G(s).
Topics: Adipocytes; Amino Acid Sequence; Cell Membrane; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrogen Peroxide; Isoproterenol; Molecular Sequence Data; NADPH Oxidases | 2000 |
Enhanced cardiac function in transgenic mice expressing a Ca(2+)-stimulated adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Calcium; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; Diastole; Echocardiography; Guanosine 5'-O-(3-Thiotriphosphate); Heart; Heart Rate; Hemodynamics; Humans; Isoproterenol; Kinetics; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Receptors, Adrenergic, beta; Restriction Mapping; Systole | 2000 |
Volume overload cardiac hypertrophy exhibits decreased expression of g(s)alpha and not of g(i)alpha in heart.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Arteriovenous Shunt, Surgical; Blood Pressure; Blotting, Northern; Body Weight; Cardiomegaly; Colforsin; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Male; Myocardium; Organ Size; Protein Isoforms; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Fluoride | 2000 |
The olfactory G protein G(alphaolf) possesses a lower GDP-affinity and deactivates more rapidly than G(salphashort): consequences for receptor-coupling and adenylyl cyclase activation.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Alternative Splicing; Animals; Cell Line; Cell Membrane; Dihydroalprenolol; Dobutamine; Ephedrine; Genetic Variation; GTP-Binding Protein alpha Subunits; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Isoproterenol; Kinetics; Rats; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Recombinant Proteins; Spodoptera; Transfection | 2001 |
Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Echocardiography; Guanosine 5'-O-(3-Thiotriphosphate); Hemodynamics; Humans; Isoproterenol; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Receptors, Adrenergic, beta-3; Signal Transduction; Stimulation, Chemical; Sulfonamides; Transcription, Genetic; Ventricular Function, Left | 2001 |
Impaired beta-adrenergic signaling pathway in white adipocytes of suckling fa/fa Zucker rats: a defect in receptor coupling.
Topics: Adenylyl Cyclases; Adipocytes; Animals; Animals, Newborn; Blotting, Western; Catecholamines; Colforsin; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Male; Obesity; Rats; Rats, Zucker; Receptors, Adrenergic, beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2001 |
Impaired parasympathetic heart rate control in mice with a reduction of functional G protein betagamma-subunits.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Cardiotonic Agents; Cell Membrane; Colforsin; Consciousness; Cyclic AMP; Cytosol; Electrocardiography; Electrophysiology; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Heart Rate; Heterotrimeric GTP-Binding Proteins; Isoproterenol; Mice; Mice, Transgenic; Parasympathetic Nervous System; Propranolol; Sinoatrial Node; Transgenes; Vagus Nerve; Vasodilator Agents | 2002 |
Efficient adenylyl cyclase activation by a beta2-adrenoceptor-G(i)alpha2 fusion protein.
Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Enzyme Activation; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Models, Biological; Proto-Oncogene Proteins; Receptors, Adrenergic, beta-2; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Recombinant Fusion Proteins; Spodoptera | 2002 |
Pertussis toxin-insensitive activation of the heterotrimeric G-proteins Gi/Go by the NG108-15 G-protein activator.
Topics: Animals; Brain; Carrier Proteins; Cattle; Cell Line; Cell Membrane; Colforsin; Glioma; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Isoproterenol; NAD; Neuroblastoma; Pertussis Toxin; Phosphorus Radioisotopes; Tumor Cells, Cultured | 2002 |
Activation of BK channels in GH3 cells by a c-PLA2-dependent G-protein signaling pathway.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aluminum Compounds; Animals; Arachidonic Acids; Calcium; Cell Line, Tumor; Drug Interactions; Enzyme Inhibitors; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ion Channel Gating; Isoproterenol; Membrane Potentials; Models, Biological; Oligodeoxyribonucleotides, Antisense; Patch-Clamp Techniques; Phospholipases A; Phospholipases A2; Picrotoxin; Pituitary Gland; Potassium Channels, Calcium-Activated; Propranolol; Rats; Signal Transduction; Time Factors | 2005 |
Angiotensin II-evoked enhanced expression of RGS2 attenuates Gi-mediated adenylyl cyclase signaling in A10 cells.
Topics: Adenylyl Cyclases; Angiotensin II; Cardiotonic Agents; Cells, Cultured; Colforsin; Dactinomycin; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Isoproterenol; Muscle, Smooth, Vascular; Parasympatholytics; RGS Proteins; Signal Transduction | 2005 |
Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Acetylcysteine; Adenylyl Cyclases; Animals; Antioxidants; Cells, Cultured; Colforsin; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension; Isoproterenol; MAP Kinase Signaling System; Models, Biological; Muscle, Smooth, Vascular; Onium Compounds; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Superoxides | 2005 |
Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway.
Topics: Acetylcholine; Amino Acid Substitution; Animals; Binding, Competitive; Cholera Toxin; Delayed Rectifier Potassium Channels; GAP-43 Protein; GTP-Binding Protein alpha Subunit, Gi2; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Hippocampus; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Peptides; Pertussis Toxin; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 2; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2006 |
Halothane does not inhibit the functional coupling between the beta2-adrenergic receptor and the Galphas heterotrimeric G protein.
Topics: Anesthetics, Inhalation; Animals; Calcium; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Halothane; Isoproterenol; Receptors, Adrenergic, beta-2; Swine | 2006 |
Enhanced expression of Gialpha protein and adenylyl cyclase signaling in aortas from 1 kidney 1 clip hypertensive rats.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Atrial Natriuretic Factor; Captopril; Colforsin; Dose-Response Relationship, Drug; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension, Renovascular; Immunoblotting; Isoproterenol; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renal Artery Obstruction; Signal Transduction; Sodium Fluoride; Time Factors | 2006 |
In vitro and in vivo pharmacological characterization of ethyl-4-[trans-4-[((2S)-2-hydroxy-3-[4-hydroxy-3[(methylsulfonyl)amino]-phenoxy]propyl) amino]cyclohexyl]benzoate hydrochloride (SAR150640), a new potent and selective human beta3-adrenoceptor agoni
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Benzoates; Binding, Competitive; Cell Line; Cell Line, Tumor; Cells, Cultured; Cyclic AMP; Female; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Isoproterenol; Macaca fascicularis; Molecular Structure; Myometrium; Obstetric Labor, Premature; Oxytocin; Pregnancy; Propanolamines; Receptors, Adrenergic, beta-3; Sulfonamides; Tocolytic Agents; Transfection; Uterine Contraction; Vasotocin | 2007 |
CAT-2 amplifies the agonist-evoked force of airway smooth muscle by enhancing spermine-mediated phosphatidylinositol-(4)-phosphate-5-kinase-gamma activity.
Topics: Acetylcholine; Airway Resistance; Animals; Arginase; Carbachol; Cationic Amino Acid Transporter 2; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isometric Contraction; Isoproterenol; Lung; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phosphotransferases (Alcohol Group Acceptor); Spermine; Trachea | 2007 |
Characterization of mouse heart adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Catalysis; Cations, Divalent; Cell Line; Cell Membrane; Colforsin; Enzyme Inhibitors; Female; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoenzymes; Isoproterenol; Kinetics; Metoprolol; Mice; Mice, Inbred Strains; Myocardium; Protein Isoforms; Receptors, G-Protein-Coupled; Recombinant Proteins; Spodoptera | 2009 |
G-protein-associated signal transduction processes are restored after postweaning environmental enrichment in Ts65Dn, a Down syndrome mouse model.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Carbachol; Cholinergic Agonists; Colforsin; Cyclic AMP; Disease Models, Animal; Dopamine Agonists; Down Syndrome; Environment; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Humans; Isoproterenol; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Norepinephrine; Signal Transduction | 2011 |