isoproterenol has been researched along with endothelin-1 in 88 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (17.05) | 18.2507 |
| 2000's | 56 (63.64) | 29.6817 |
| 2010's | 16 (18.18) | 24.3611 |
| 2020's | 1 (1.14) | 2.80 |
| Authors | Studies |
|---|---|
| Delpech, N; Potreau, D; Soustre, H | 1 |
| Horie, M; Obayashi, K; Sasayama, S; Tsuchiya, K; Watanuki, M | 1 |
| Endoh, M; Yang, HT; Zhu, Y | 1 |
| Karmazyn, M; Sims, SM; Thomas, GP | 1 |
| Opgenorth, TJ; Wu-Wong, JR | 1 |
| Cheng, CP; Little, WC; Ohte, N; Suzuki, M; Wang, ZM; Williams, DL | 1 |
| Brodde, OE; Heinroth-Hoffmann, I; Holtz, J; Morawietz, H; Pönicke, K; Schiewe, P; Vogelsang, M | 1 |
| D'Agostino, B; D'Amico, M; Falciani, M; Filippelli, A; Filippelli, W; Piucci, B; Rossi, F | 1 |
| D'Amico, M; Di Filippo, C; Rossi, F | 1 |
| Ahluwalia, A; Scotland, R; Vallance, P | 1 |
| Endoh, M; Norota, I; Sakurai, K; Sugawara, H; Watanabe, T; Yang, HT | 1 |
| Catalán, RE; Hernández, F; Martinez, AM | 1 |
| Fujihara, H; Fujiwara, N; Fukuda, S; Kinoshita, H; Kokubun, S; Nishimaki, H; Shimoji, K; Toriumi, T; Xu, H | 1 |
| Kurabayashi, M; Nagai, R; Okajima, F; Sekiguchi, K; Yokoyama, T | 1 |
| Endoh, M; Watanabe, T | 2 |
| Brunton, LL; Endo-Mochizuki, Y; Gonzalez, AM; Meszaros, JG; Villarreal, F; Villegas, S | 1 |
| Calcerrada, MC; Catalán, RE; Hernández, F; Martínez, AM; Pérez-Alvarez, MJ | 1 |
| Dibas, AI; Prasanna, G; Yorio, T | 1 |
| Bond, BR; Dorman, BH; McElmurray, JH; Mukherjee, R; Mukhin, YV; New, RB; Spinale, FG | 1 |
| Catalán, RE; Hernández, F; Martínez, AM; Piedra, D | 1 |
| Allen, JD; Kelso, EJ; McDermott, BJ; Silke, B; Spiers, JP | 1 |
| Endoh, M; Sakurai, K; Wang, H | 1 |
| Araki, M; Fujita, M; Hasegawa, K; Iwai-Kanai, E; Kakita, T; Morimoto, T; Sasayama, S; Sawamura, T; Wada, H | 1 |
| Hayashi, K; Iwamoto, K; Kizawa, Y; Kusama, T; Murakami, H; Saito, K; Sano, M | 1 |
| Brehm, BR; Heinle, H; Risler, T; Wolf, SC | 1 |
| Bányász, T; Iost, N; Körtvély, A; Magyar, J; Nánási, PP; Opincariu, M; Papp, JG; Szécsi, J; Szigligeti, P; Varró, A; Virág, L | 1 |
| Bányász, T; Körtvély, A; Kovács, L; Magyar, J; Mohácsi, A; Nánási, PP; Papp, Z; Szigeti, G; Szigligeti, P | 1 |
| Browning, DD; Dulin, NO; Niu, J; Voyno-Yasenetskaya, T; Ye, RD | 1 |
| Hasegawa, K; Kaburagi, S; Kakita, T; Morimoto, T; Sasayama, S; Wada, H; Yanazume, T | 1 |
| Bond, BR; Coker, ML; Etoh, T; Holder, JR; Joffs, C; Jolly, JR; Spinale, FG | 1 |
| Chen, JJ; Cheng, TH; Hong, HJ; Lee, FY; Li, CY; Lin, CI; Loh, SH; Tsai, CS | 1 |
| Hancox, JC; James, AF; Zhang, YH | 1 |
| Kemnitz, KR; Kranias, EG; Pi, Y; Walker, JW; Zhang, D | 1 |
| Brehm, BR; Freudenberg, J; Friedmann, F; Heinle, H; Schulze-Osthoff, K; Wolf, SC | 1 |
| Michel, MC; Peters, SL; Pfaffendorf, M; Sand, C; Van Zwieten, PA | 1 |
| Berg, CE; Dayton, BD; Wu-Wong, JR | 1 |
| Földes, G; Ilves, M; Pikkarainen, S; Piuhola, J; Ruskoaho, H; Rysä, J; Szokodi, I; Tavi, P; Tokola, H; Tóth, M; Voutilainen-Myllylä, S | 1 |
| Aass, H; Andersen, GØ; Osnes, JB; Qvigstad, E; Schiander, I; Skomedal, T | 1 |
| Hancox, JC; Hinde, AK; James, AF; Zhang, YH | 1 |
| Goraca, A | 1 |
| Kajimoto, K; Molina, CA; Nazmy, M; Sadoshima, J; Tomita, H; Yehia, G | 1 |
| Kemnitz, KR; Pi, Y; Walker, JW; Wang, H; Zhang, D | 1 |
| Balijepalli, RC; Kamp, TJ; Pfeiffer, ES; Pi, Y; Robia, SL; Robu, VG; Walker, JW | 1 |
| Gilbert, P; Thorin, E | 1 |
| De Salvatore, G; De Salvia, MA; Mitolo, CI; Mitolo-Chieppa, D; Nacci, C; Natale, L; Piepoli, AL; Porro, C | 1 |
| Eigel, BN; Gursahani, H; Hadley, RW | 1 |
| Juhász-Nagy, A; Kékesi, V; Kiss, O; Merkely, B; Soós, P; Zima, E | 1 |
| Chang, L; Geng, B; Li, GZ; Pan, CS; Qi, YF; Tang, CS; Zhao, J | 1 |
| Bell, D; McDermott, BJ | 1 |
| Endoh, M; Hayasaka, K; Ishigaki, D; Ishii, K; Lin, C; Nagai, M | 1 |
| Chu, L; Endoh, M; Norota, I | 1 |
| Didié, M; Engmann, S; Eschenhagen, T; Mühlhäuser, U; Münzel, F; Schneiderbanger, K; Schubert, P; Zimmermann, WH; Zolk, O | 1 |
| Ronkainen, J; Ruskoaho, H; Vierimaa, H; Vuolteenaho, O | 1 |
| Kane, KA; Rankin, AC; Redpath, CJ; Workman, AJ | 1 |
| Berridge, MJ; Bootman, MD; Capper, SJ; Conway, SJ; Horton, JK; Proven, A; Roderick, HL | 1 |
| Dedman, JR; Kaetzel, MA; Li, B | 1 |
| Grünberger, C; Klar, J; Kurtz, A; Obermayer, B; Schweda, F | 1 |
| Avkiran, M; Bardswell, SC; Cuello, F; Haworth, RS; Kentish, JC; Lutz, S; Mayr, M; Wieland, T; Yin, X | 1 |
| Dulin, NO; Hogarth, K; Sandbo, N; Taurin, S; Yau, DM | 1 |
| Belcher, E; Harding, SE; Mitchell, JA; Patel, TA; Warner, TD | 1 |
| Avkiran, M; Cuello, F; Haworth, RS; Roberts, NA | 1 |
| Behnke, BJ; Delp, MD; Donato, AJ; Laughlin, MH; Lesniewski, LA; Ray, CA; Woodman, CR | 1 |
| Barbieri, SF; Brar, BK; Gattuso, A; Mahata, SK; Mannarino, C; Mazza, R; Tota, B | 1 |
| Forster, ME; Foster, JM; Olson, KR | 1 |
| Dai, DZ; Dai, Y; Ji, H; Tang, XY; Xu, M | 1 |
| Angelone, T; Brar, BK; Cerra, MC; Limchaiyawat, PT; Mahata, SK; Quintieri, AM; Tota, B | 1 |
| Alloatti, G; Angelone, T; Boero, O; Brero, A; Cerra, MC; Filice, E; Gallo, MP; Guérold, B; Levi, R; Metz-Boutigue, MH; Pulerà, E; Quintieri, AM; Ramella, R; Shooshtarizadeh, P; Tota, B | 1 |
| Copaja Soto, M; Díaz-Araya, G; Jalil, JE; Lavandero, S; Lijnen, P; Ordenes, GE; Paz Ocaranza, M; Saldaña, A; Valenzuela, R; Vio, C; Vivar Sanchez, R | 1 |
| Chen, CX; Gao, JP; Gu, WL; Lü, J; Wang, Y | 1 |
| Diéguez, G; Fernández, N; García-Villalón, AL; Monge, L; Salcedo, A | 1 |
| Avkiran, M; Cuello, F; Ehler, E; Hao, Z; Hornshaw, M; Mayr, M; Mayr, U; Yin, X | 1 |
| Chidiac, P; Kirshenbaum, LA; Nunn, C; Roy, AA; Sobiesiak, AJ; Zou, MX | 1 |
| Chen, CX; Gao, JP; Gu, WL; Lü, J; Wang, Y; Wu, Q | 1 |
| Bers, DM; Blatter, LA; Bodi, I; DeSantiago, J; Domeier, TL; Lorenz, JN; Maillet, M; Mikoshiba, K; Molkentin, JD; Nakayama, H | 1 |
| Hong, HM; Kabir, MH; Lee, C; Oh, E; Song, EJ; Yoo, YS | 1 |
| Crider, JY; Sharif, NA | 1 |
| Bers, DM; Bossuyt, J; Erickson, JR; Ferguson, A; Patel, R | 1 |
| Allen, BG; Chatenet, D; Fournier, A; Glazkova, I; Hébert, TE; Merlen, C; Nattel, S; Smith, C; Tadevosyan, A; Therien, M; Trieu, P; Vaniotis, G; Villeneuve, LR | 1 |
| Gabrielson, K; Gao, WD; Murphy, A; Paolocci, N; Ramirez-Correa, G; Shen, X; Tan, Z; Tian, Y; Wang, X; Yu, B; Zhong, X | 1 |
| Cui, WY; Duan, L; Long, CL; Wang, H; Zhang, YF; Zhong, ML; Zhou, HM | 1 |
| Abdul-Ghani, M; Brunette, S; Dick, SA; Fernando, P; Megeney, LA; Putinski, C; Stiles, R | 1 |
| Chen, M; Gao, E; Huang, S; Shang, X; Sun, J; Talarico, JA; Tilley, DG; Wang, N; Yan, G; Yi, B; Zhang, GX; Zhu, N | 1 |
| Arias-Loza, PA; Berbner, A; Czolbe, M; Dedkova, EN; Heinze, KG; Kaspar, M; Kuhn, J; Kwong, JQ; Molkentin, JD; Ritter, O; Seidlmayer, LK; Williams, T | 1 |
| Liu, S; Premont, RT; Rockey, DC; Singh, S | 1 |
| Dempsie, Y; Foote, BE; Htet, M; Martin, PE; Nally, JE; Shaw, A | 1 |
| Dong, WR; Li, ZH; Liu, SM; Lu, F; Yu, H; Zhang, N | 1 |
| Chen, X; Fan, S; Liu, P; Xiao, Q; Yao, E; Zhang, J; Zhang, Y | 1 |
88 other study(ies) available for isoproterenol and endothelin-1
| Article | Year |
|---|---|
Endothelin-1 inhibits L-type Ca2+ current enhanced by isoprenaline in rat atrial myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Endothelin-1; Heart Atria; Isoproterenol; Myocardium; Patch-Clamp Techniques; Protein Kinase Inhibitors; Rats | 1997 |
Endothelin-1 inhibition of cardiac ATP-sensitive K+ channels via pertussis-toxin-sensitive G-proteins.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Animals; Carbachol; Depression, Chemical; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Female; GTP-Binding Proteins; Guinea Pigs; Isoproterenol; Male; Muscarinic Agonists; Myocardium; Ouabain; Patch-Clamp Techniques; Peptides, Cyclic; Pertussis Toxin; Potassium Channels; Sodium-Potassium-Exchanging ATPase; Sympathomimetics; Virulence Factors, Bordetella | 1997 |
Negative chronotropic and inotropic effects of endothelin isopeptides in mammalian cardiac muscle.
Topics: Animals; Cyclic AMP; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Heart Atria; Heart Rate; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Mammals; Myocardial Contraction; Myocardium; Peptides, Cyclic; Pertussis Toxin; Prazosin; Rabbits; Receptor, Endothelin A; Receptor, Endothelin B; Virulence Factors, Bordetella | 1997 |
Differential effects of endothelin-1 on basal and isoprenaline-enhanced Ca2+ current in guinea-pig ventricular myocytes.
Topics: Animals; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Guinea Pigs; Heart; Heart Ventricles; Indoles; Isoenzymes; Isoproterenol; Kinetics; Maleimides; Membrane Potentials; Molsidomine; Nitric Oxide; Nystatin; Patch-Clamp Techniques; Pertussis Toxin; Protein Kinase C; Virulence Factors, Bordetella | 1997 |
Endothelin and isoproterenol counter-regulate cAMP and mitogen-activated protein kinases.
Topics: Adrenergic beta-Agonists; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromatography, Ion Exchange; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Endothelin-1; Enzyme Activation; Humans; Isoproterenol | 1998 |
Altered inotropic response of endothelin-1 in cardiomyocytes from rats with isoproterenol-induced cardiomyopathy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Cardiotonic Agents; Cell Size; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Heart Failure; Hemodynamics; Isoproterenol; Male; Myocardial Contraction; Myocardium; Peptides, Cyclic; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Sodium-Hydrogen Exchangers; Staurosporine | 1998 |
Mechanism of ET(A)-receptor stimulation-induced increases in intracellular Ca2+ in SK-N-MC cells.
Topics: Adrenergic beta-Agonists; Calcium; Cells, Cultured; Cyclic AMP; Drug Interactions; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-2; Humans; Inositol Phosphates; Iodine Radioisotopes; Isoproterenol; Neuroblastoma; Peptides, Cyclic; Receptor, Endothelin A; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vasoconstrictor Agents; Viper Venoms | 1998 |
Endothelin-1 affects capsaicin-evoked release of neuropeptides from rat vas deferens.
Topics: Animals; Bronchodilator Agents; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Endothelin-1; Humans; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Neuropeptides; Papaverine; Rats; Rats, Wistar; Tetrodotoxin; Vas Deferens; Vasodilator Agents | 1999 |
Adrenoceptors modulate depressor responses of endothelin-1 into the superior colliculus of rats.
Topics: Acebutolol; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Albuterol; Animals; Blood Pressure; Clonidine; Dobutamine; Endothelin-1; Isoproterenol; Male; Microinjections; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-1; Superior Colliculi | 1999 |
On the regulation of tone in vasa vasorum.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Aorta; Bradykinin; Calcitonin Gene-Related Peptide; Cattle; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Isoproterenol; Norepinephrine; Prostaglandin Endoperoxides, Synthetic; Substance P; Swine; Vasa Vasorum; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Role of Na+/Ca2+ exchange in endothelin-1-induced increases in Ca2+ transient and contractility in rabbit ventricular myocytes: pharmacological analysis with KB-R7943.
Topics: Animals; Calcium; Cardiotonic Agents; Cell Size; Drug Interactions; Endothelin-1; Fluorescent Dyes; Heart; Heart Ventricles; Indoles; Isoproterenol; Male; Myocardial Contraction; Myocardium; Rabbits; Sodium-Calcium Exchanger; Spectrometry, Fluorescence; Thiourea; Ventricular Function | 1999 |
Endothelin enhances adenosine and isoprenaline elevated cyclic AMP levels in rat cerebellar slices.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebellum; Colforsin; Cyclic AMP; Endothelin Receptor Antagonists; Endothelin-1; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Wistar; Receptors, Endothelin; Tritium | 1999 |
Enhanced beta-receptor-mediated vasorelaxation in hypoxic porcine coronary artery.
Topics: Animals; Arteries; Coronary Vessels; Cyclic AMP; Endothelin-1; Glyburide; Hypoxia; In Vitro Techniques; Isoproterenol; Oxygen; Potassium Chloride; Receptors, Adrenergic, beta; Swine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1999 |
Sphingosylphosphorylcholine induces a hypertrophic growth response through the mitogen-activated protein kinase signaling cascade in rat neonatal cardiac myocytes.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Cell Size; Endothelin-1; Enzyme Inhibitors; Flavonoids; GTP-Binding Proteins; Heart; Hypertrophy; Isoproterenol; MAP Kinase Signaling System; Muscle Proteins; Myocardium; Pertussis Toxin; Phosphorylation; Phosphorylcholine; Protein Processing, Post-Translational; Rats; Sphingosine; Virulence Factors, Bordetella | 1999 |
Characterization of the endothelin-1-induced regulation of L-type Ca2+ current in rabbit ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Azepines; Calcium; Calcium Channels, L-Type; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Heart Ventricles; In Vitro Techniques; Indoles; Isoproterenol; Male; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Phosphodiesterase Inhibitors; Protein Kinase C; Rabbits; Receptor, Endothelin A; Receptor, Endothelin B; Virulence Factors, Bordetella | 1999 |
Identification of G protein-coupled signaling pathways in cardiac fibroblasts: cross talk between G(q) and G(s).
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Angiotensin II; Animals; Bradykinin; Calcium; Carbachol; Cardiotonic Agents; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Isoproterenol; Male; Myocardium; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Signal Transduction; Sympathomimetics; Type C Phospholipases; Uridine Triphosphate; Vasoconstrictor Agents | 2000 |
Endothelin-1 increases isoprenaline-enhanced cyclic AMP levels in cerebral cortex.
Topics: Adenosine Deaminase; Adrenergic beta-Agonists; Animals; Calcium; Cerebral Cortex; Cyclic AMP; Endothelin Receptor Antagonists; Endothelin-1; Isoproterenol; Male; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Wistar | 2000 |
Cholinergic and adrenergic modulation of the Ca2+ response to endothelin-1 in human ciliary muscle cells.
Topics: Adrenergic Agonists; Bucladesine; Calcium; Carbachol; Cell Line; Cholinergic Agonists; Ciliary Body; Cyclic AMP; Dose-Response Relationship, Drug; Drug Combinations; Endothelin-1; Estrenes; Fura-2; Humans; Isoproterenol; Muscle, Smooth; Norepinephrine; Pyrrolidinones; Radioimmunoassay; Type C Phospholipases | 2000 |
Myocyte endothelin exposure during cardioplegic arrest exacerbates contractile dysfunction after reperfusion.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Endothelin-1; Heart Arrest, Induced; Heart Ventricles; In Vitro Techniques; Isoproterenol; Microscopy, Video; Myocardial Contraction; Myocardial Reperfusion; Myocardium; Swine | 2000 |
Endothelin inhibits histamine-induced cyclic AMP accumulation in bovine brain vessels.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood-Brain Barrier; Brain; Capillaries; Cattle; Cyclic AMP; Endothelin Receptor Antagonists; Endothelin-1; Histamine; Histamine Antagonists; Isoproterenol; Microcirculation; Oligopeptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Second Messenger Systems; Viper Venoms | 2000 |
Inotropic response to endothelin-1, isoprenaline and calcium in cardiomyocytes isolated from endotoxin treated rats: effects of ethyl-isothiourea and dexamethasone.
Topics: Animals; Calcium; Dexamethasone; Dose-Response Relationship, Drug; Endothelin-1; Endotoxins; Heart Ventricles; Isoproterenol; Isothiuronium; Lipopolysaccharides; Male; Myocardial Contraction; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; RNA, Messenger; Ventricular Function | 2000 |
Antiadrenergic effects of endothelin-1 on the L-type Ca2+ current in dog ventricular myocytes.
Topics: Adrenergic Antagonists; Animals; Calcium Channels, L-Type; Dogs; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Female; Heart; Isoproterenol; Male; Oligopeptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B | 2000 |
Pharmacological analysis by HOE642 and KB-R9032 of the role of Na(+)/H(+) exchange in the endothelin-1-induced Ca(2+) signalling in rabbit ventricular myocytes.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Signaling; Cardiotonic Agents; Endothelin-1; Guanidines; Heart Ventricles; In Vitro Techniques; Indoles; Isoproterenol; Male; Myocardium; Oxazines; Rabbits; Sodium-Hydrogen Exchangers; Sulfones | 2000 |
Endothelin-1 as a protective factor against beta-adrenergic agonist-induced apoptosis in cardiac myocytes.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Anti-Bacterial Agents; Apoptosis; Azepines; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Flavonoids; Heart; Indoles; Isoproterenol; Myocardium; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sirolimus | 2000 |
Involvement of angiotensin II and endothelin-1 in the development of submandibular gland hypertrophy in response to isoproterenol in rats.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Dobutamine; Enalapril; Endothelin-1; Hypertrophy; Isoproterenol; Male; Rats; Rats, Wistar; Submandibular Gland | 2000 |
Chronically elevated endothelin-1 concentrations modulate the beta-adrenergic receptor system in vitro and in vivo.
Topics: Adenylyl Cyclases; Animals; Endothelin-1; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta | 2000 |
Effects of endothelin-1 on calcium and potassium currents in undiseased human ventricular myocytes.
Topics: Action Potentials; Adrenergic beta-Agonists; Calcium Channels, L-Type; Electric Conductivity; Endothelin-1; Heart; Humans; Isoproterenol; Myocardium; Patch-Clamp Techniques; Potassium Channels | 2000 |
Different effects of endothelin-1 on calcium and potassium currents in canine ventricular cells.
Topics: Action Potentials; Analysis of Variance; Animals; Calcium Channels; Cardiotonic Agents; Cyclic AMP; Dogs; Endothelin-1; Heart Ventricles; Isoproterenol; Myocardial Contraction; Patch-Clamp Techniques; Potassium Channels | 2001 |
Cyclic AMP-independent activation of protein kinase A by vasoactive peptides.
Topics: Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Endothelin-1; Enzyme Activation; HeLa Cells; Humans; I-kappa B Proteins; Isoproterenol; Leupeptins; Mice; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Proteasome Endopeptidase Complex; Receptor, Endothelin A; Receptors, Endothelin; Recombinant Proteins; Transfection | 2001 |
Calcineurin-GATA4 pathway is involved in beta-adrenergic agonist-responsive endothelin-1 transcription in cardiac myocytes.
Topics: Adrenergic beta-Agonists; Animals; Calcineurin; Cyclosporine; DNA-Binding Proteins; Endothelin-1; GATA4 Transcription Factor; Isoproterenol; Myocardium; NFATC Transcription Factors; Norepinephrine; Nuclear Proteins; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Transcription Factors; Transcription, Genetic | 2001 |
Matrix metalloproteinase expression and activity in isolated myocytes after neurohormonal stimulation.
Topics: Angiotensin II; Animals; Cardiotonic Agents; Cells, Cultured; Endothelin-1; Gene Expression Regulation, Enzymologic; Isoproterenol; Matrix Metalloproteinases; Myocardial Contraction; Swine; Ventricular Function | 2001 |
Inhibitory effect of endothelin-1 on the isoproterenol-induced chloride current in human cardiac myocytes.
Topics: Adrenergic beta-Agonists; Adult; Aged; Atrial Function; Chloride Channels; Chlorides; Colforsin; Endothelin-1; Female; Heart Atria; Heart Ventricles; Humans; Isoproterenol; Male; Membrane Potentials; Middle Aged; Time Factors; Ventricular Function | 2001 |
Regulation by endothelin-1 of Na+-Ca2+ exchange current (I(NaCa)) from guinea-pig isolated ventricular myocytes.
Topics: Adrenergic beta-Agonists; Alkaloids; Animals; Benzophenanthridines; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Kinetics; Male; Myocardium; Patch-Clamp Techniques; Phenanthridines; Phorbol Esters; Protein Kinase C; Sodium-Calcium Exchanger | 2001 |
Phosphorylation of troponin I controls cardiac twitch dynamics: evidence from phosphorylation site mutants expressed on a troponin I-null background in mice.
Topics: Animals; Calcium; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Endothelin-1; Gene Expression Regulation; Heart; In Vitro Techniques; Isoproterenol; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Myocardial Contraction; Phosphorylation; Protein Kinase C; Signal Transduction; Troponin I | 2002 |
Modulation of the beta-adrenergic receptor system of vascular smooth muscle cells in vitro and in vivo by chronically elevated endothelin-1 levels.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Endothelin-1; Heterotrimeric GTP-Binding Proteins; Isoproterenol; Muscle, Smooth, Vascular; Rats; Receptors, Adrenergic, beta-2 | 2002 |
A mitogen-activated protein kinase is involved in the inotropic but not chronotropic actions of adrenoceptor agonists and endothelin-1.
Topics: Adrenergic Agonists; Adrenergic alpha-1 Receptor Agonists; Analysis of Variance; Animals; Butadienes; Endothelin-1; Enzyme Inhibitors; Flavonoids; Heart Rate; Imidazoles; Isoproterenol; Male; MAP Kinase Signaling System; Methoxamine; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardial Contraction; Nitriles; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 2002 |
Endothelin-stimulated glucose uptake: effects of intracellular Ca(2+), cAMP and glucosamine.
Topics: 3T3 Cells; Adenylyl Cyclases; Animals; Animals, Newborn; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Activators; Fibroblasts; Glucosamine; Glucose; Hexosamines; Insulin; Interleukin 1 Receptor Antagonist Protein; Isoproterenol; Mice; Myocardium; Rats; Sialoglycoproteins; Stimulation, Chemical | 2002 |
Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility.
Topics: Adrenomedullin; Animals; Animals, Genetically Modified; Apelin; Apelin Receptors; Calcium Channels; Carrier Proteins; Dose-Response Relationship, Drug; Endothelin-1; Gene Expression Regulation; Heart Ventricles; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Isoproterenol; Ligands; Male; Membrane Potentials; Myocardial Contraction; Peptides; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, G-Protein-Coupled; RNA, Messenger; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Stress, Mechanical; Time Factors; Ventricular Function | 2002 |
Alpha(1)-AR-induced positive inotropic response in heart is dependent on myosin light chain phosphorylation.
Topics: Animals; Azepines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cardiotonic Agents; Endothelin-1; Enzyme Inhibitors; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoproterenol; MAP Kinase Signaling System; Myocardial Contraction; Myosin Light Chains; Papillary Muscles; Phenylephrine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Receptors, Adrenergic, alpha-1; Receptors, Endothelin; rho-Associated Kinases; Tetradecanoylphorbol Acetate | 2002 |
Modulation of the Na+/Ca2+ exchanger by isoprenaline, adenosine, and endothelin-1 in guinea pig ventricular myocytes.
Topics: Adenosine; Animals; Endothelin-1; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscle Cells; Sodium-Calcium Exchanger | 2002 |
Negative chronotropic effect of endothelin-1 (ET-1) in the cardiac pacemaker tissue.
Topics: Animals; Antihypertensive Agents; Cardiotonic Agents; Depression, Chemical; Electrocardiography; Endothelin Receptor Antagonists; Endothelin-1; Heart Atria; Heart Rate; Isoproterenol; Oligopeptides; Prazosin; Rats | 2003 |
Inducible cAMP early repressor (ICER) is a negative-feedback regulator of cardiac hypertrophy and an important mediator of cardiac myocyte apoptosis in response to beta-adrenergic receptor stimulation.
Topics: Adenoviridae; Adrenergic beta-Agonists; Animals; Animals, Newborn; Apoptosis; Cardiomegaly; Cell Size; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element Modulator; DNA-Binding Proteins; Endothelin-1; Feedback, Physiological; Gene Expression Regulation; Genetic Vectors; Immunohistochemistry; Isoproterenol; Male; Myocytes, Cardiac; Phenylephrine; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Repressor Proteins; RNA, Messenger; Transfection | 2003 |
Protein kinase C and A sites on troponin I regulate myofilament Ca2+ sensitivity and ATPase activity in the mouse myocardium.
Topics: Actin Cytoskeleton; Adenosine Triphosphatases; Adrenergic beta-Agonists; Alanine; Amino Acid Substitution; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; In Vitro Techniques; Isometric Contraction; Isoproterenol; Mice; Mice, Transgenic; Mutation; Myocardial Contraction; Myocardium; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Troponin I | 2003 |
Localization of functional endothelin receptor signaling complexes in cardiac transverse tubules.
Topics: Animals; Blotting, Western; Dogs; Dose-Response Relationship, Drug; Endothelin-1; Fluorescein; Green Fluorescent Proteins; Heart Ventricles; Isoenzymes; Isoproterenol; Kinetics; Luminescent Proteins; Male; Microscopy, Fluorescence; Models, Biological; Models, Chemical; Myocardium; Myocytes, Cardiac; Phospholipase C beta; Photons; Protein Binding; Protein Kinase C; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Signal Transduction; Type C Phospholipases | 2003 |
Endothelin-1 limits vascular smooth muscle beta-adrenergic receptor sensitivity by a PKC-dependent pathway.
Topics: Alkaloids; Animals; Aorta, Thoracic; Benzophenanthridines; Colforsin; Cyclosporine; Endothelin Receptor Antagonists; Endothelin-1; Female; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenanthridines; Phenylephrine; Protein Kinase C; Rabbits; Receptors, Adrenergic, beta; Receptors, Endothelin; Vasodilation | 2003 |
Effects of in vivo treatment with interleukins 1beta and 6 on rat mesenteric vascular bed reactivity.
Topics: Acetylcholine; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Endothelin-1; Fever; Guanethidine; Inflammation; Interleukin-1; Interleukin-6; Intestinal Mucosa; Isomerism; Isoproterenol; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Norepinephrine; Perfusion; Rats; Rats, Sprague-Dawley; Sumatriptan; Time Factors; Vascular Resistance; Vasoconstriction; Vasodilation | 2003 |
Na+/Ca2+ exchanger plays a key role in inducing apoptosis after hypoxia in cultured guinea pig ventricular myocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Apoptosis; Cells, Cultured; Endothelin-1; Female; Guinea Pigs; Heart Ventricles; Hydrogen Peroxide; Hypoxia; Isoproterenol; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oligonucleotides, Antisense; Oxidants; Oxygen; Phenylephrine; Sodium-Calcium Exchanger | 2004 |
Intracoronary endothelin-1 infusion combined with systemic isoproterenol treatment: antagonistic arrhythmogenic effects.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Atrial Fibrillation; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Drug Antagonism; Drug Therapy, Combination; Electrocardiography; Endothelin-1; Heart Ventricles; Hemodynamics; Infusions, Intra-Arterial; Infusions, Intravenous; Isoproterenol; Ventricular Fibrillation; Ventricular Function, Left | 2004 |
Ghrelin protects myocardium from isoproterenol-induced injury in rats.
Topics: Animals; Cardiotonic Agents; Endothelin-1; Ghrelin; Isoproterenol; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Ischemia; Myocardium; Peptide Hormones; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2004 |
Effects of rosiglitazone and interactions with growth-regulating factors in ventricular cell hypertrophy.
Topics: Animals; Cell Survival; Cells, Cultured; Culture Media; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Glucose; Heart Ventricles; Hypertrophy; Insulin; Insulin-Like Growth Factor I; Isoproterenol; Male; Myocytes, Cardiac; Norepinephrine; Phenylalanine; Rats; Rats, Sprague-Dawley; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazolidinediones | 2005 |
Cross-talk between beta(1)-adrenoceptors and ET(A) receptors in modulation of the slow component of delayed rectifier K(+) currents.
Topics: Adrenergic beta-Agonists; Animals; Cloning, Molecular; Electric Stimulation; Electrophysiology; Endothelin-1; Female; Isoproterenol; Oocytes; Patch-Clamp Techniques; Potassium Channels; Receptor, Endothelin A; Receptors, Adrenergic, beta-1; Xenopus | 2005 |
Differential inhibition by the Rho kinase inhibitor Y-27632 of the increases in contractility and Ca2+ transients induced by endothelin-1 in rabbit ventricular myocytes.
Topics: Adrenergic beta-Agonists; Amides; Animals; Calcium; Cell Size; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Fluorescent Dyes; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Papillary Muscles; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases | 2005 |
Endothelin-1 and isoprenaline co-stimulation causes contractile failure which is partially reversed by MEK inhibition.
Topics: Actins; Animals; Atrial Natriuretic Factor; Butadienes; Depression, Chemical; Endothelin-1; Gene Expression Regulation; Heart Failure; Isoproterenol; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Myocardial Contraction; Myocardium; Myosin Heavy Chains; Nitriles; Protein Isoforms; Rats; Rats, Wistar; RNA, Messenger; Stimulation, Chemical; Tissue Engineering | 2005 |
Synergistic activation of salmon cardiac function by endothelin and beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Animals; Dose-Response Relationship, Drug; Drug Synergism; Endothelin Receptor Antagonists; Endothelin-1; Female; Fish Proteins; Gene Expression Regulation; Heart; Isoproterenol; Male; Myocardial Contraction; Natriuretic Peptides; Oligopeptides; Piperidines; RNA, Messenger; Salmo salar | 2006 |
Anti-adrenergic effects of endothelin on human atrial action potentials are potentially anti-arrhythmic.
Topics: Action Potentials; Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Calcium Channels; Endothelin-1; Endothelins; Female; Heart Atria; Humans; Isoproterenol; Male; Middle Aged | 2006 |
Inositol 1,4,5-trisphosphate supports the arrhythmogenic action of endothelin-1 on ventricular cardiac myocytes.
Topics: Animals; Arrhythmias, Cardiac; Boron Compounds; Calcium; Calcium Channels; Calcium Signaling; Digoxin; Endothelin-1; Heart Ventricles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoproterenol; Myocytes, Cardiac; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Type C Phospholipases | 2006 |
Signaling pathways regulating murine cardiac CREB phosphorylation.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Heart; Isoenzymes; Isoproterenol; Mice; Molecular Sequence Data; Myocardial Reperfusion; Myocardium; Phosphorylation; Phosphoserine; Protein Kinase C-epsilon; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Endothelin-1; Enzyme Inhibitors; Exocytosis; In Vitro Techniques; Intracellular Membranes; Isoproterenol; Kidney; Mice; Mice, Inbred C57BL; Renin; RNA, Small Interfering; Thapsigargin | 2006 |
Protein kinase D selectively targets cardiac troponin I and regulates myofilament Ca2+ sensitivity in ventricular myocytes.
Topics: Actin Cytoskeleton; Adrenergic beta-Agonists; Animals; Calcium; Cells, Cultured; Endothelin-1; Gene Transfer Techniques; Genes, Reporter; Green Fluorescent Proteins; Heart Ventricles; Isoproterenol; Mice; Myocytes, Cardiac; Phosphorylation; Protein Kinase C; Rats; Sarcomeres; Troponin I | 2007 |
Gbetagamma-mediated prostacyclin production and cAMP-dependent protein kinase activation by endothelin-1 promotes vascular smooth muscle cell hypertrophy through inhibition of glycogen synthase kinase-3.
Topics: Adrenergic beta-Agonists; Animals; Autocrine Communication; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 1; Endothelin-1; Enzyme Activation; Epoprostenol; Glycogen Synthase Kinase 3; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Hypertrophy; Isoproterenol; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Rats; Rats, Inbred WKY; Signal Transduction; Vasoconstrictor Agents | 2007 |
Identification and characterization of a dysfunctional cardiac myocyte phenotype: role of bacteria, Toll-like receptors, and endothelin.
Topics: Animals; Atrasentan; Bacteria; Cell Size; Cell Survival; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Escherichia coli; Female; Gene Expression; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Pyrrolidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staphylococcus aureus; Toll-Like Receptors | 2007 |
Regulation of protein kinase D activity in adult myocardium: novel counter-regulatory roles for protein kinase Cepsilon and protein kinase A.
Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Heart Ventricles; Isoproterenol; Isoquinolines; Male; Mice; Myocardium; Myocytes, Cardiac; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate; Troponin I | 2007 |
Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension.
Topics: Animals; Arterioles; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Down-Regulation; Endothelin-1; Enzyme Inhibitors; Hypertension; Insulin; Isoproterenol; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; Potassium Chloride; Prediabetic State; Rats; Rats, Zucker; Signal Transduction; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Catestatin (chromogranin A344-364) is a novel cardiosuppressive agent: inhibition of isoproterenol and endothelin signaling in the frog heart.
Topics: Animals; Calcium-Binding Proteins; Cardiotonic Agents; Cattle; Chromogranin A; Depression, Chemical; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Oxadiazoles; Peptide Fragments; Phosphorylation; Piperidines; Quinoxalines; Rana esculenta; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Stroke Volume | 2008 |
Different sensitivities of arteries and veins to vasoactive drugs in a hagfish, Eptatretus cirrhatus.
Topics: Animals; Arteries; Carbachol; Dose-Response Relationship, Drug; Endothelin-1; Hagfishes; Isoproterenol; Myography; Phenylephrine; Vasoconstriction; Vasoconstrictor Agents; Vasotocin; Veins | 2008 |
Protective effect of the endothelin antagonist CPU0213 against isoprenaline-induced heart failure by suppressing abnormal expression of leptin, calcineurin and SERCA2a in rats.
Topics: Animals; Calcineurin; Cardiotonic Agents; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression Regulation; Heart Failure; Isoproterenol; Leptin; Male; Propranolol; Pyrazoles; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2008 |
The antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropism.
Topics: Animals; Antihypertensive Agents; Cardiomyopathies; Cardiotonic Agents; Chromogranin A; Coronary Circulation; Endothelin-1; Heart Rate; Humans; Hypertension; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Paracrine Communication; Peptide Fragments; Perfusion; Rats; Rats, Wistar; Signal Transduction; Sympathetic Nervous System; Vasodilation; Ventricular Pressure | 2008 |
The homologous rat chromogranin A1-64 (rCGA1-64) modulates myocardial and coronary function in rat heart to counteract adrenergic stimulation indirectly via endothelium-derived nitric oxide.
Topics: Animals; Aorta; Autocrine Communication; Calcium; Cardiotonic Agents; Cattle; Chromogranin A; Coronary Vessels; Endothelial Cells; Endothelin-1; Humans; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide; Papillary Muscles; Paracrine Communication; Phosphatidylinositol 3-Kinases; Rats; Rats, Wistar; Structure-Activity Relationship; Vasodilation | 2008 |
Early expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin-converting enzyme polymorphism.
Topics: Animals; Cardiomegaly; Cell Proliferation; Chemokine CCL2; Collagen; Endothelin-1; Fibroblasts; Fibronectins; Fibrosis; Gene Expression Regulation; Heart Ventricles; Inflammation Mediators; Isoproterenol; Matrix Metalloproteinase 2; Myocardium; Peptidyl-Dipeptidase A; Polymorphism, Single Nucleotide; Rats; RNA, Messenger; Transforming Growth Factor beta1 | 2008 |
Effect of sodium houttuyfonate on myocardial hypertrophy in mice and rats.
Topics: Alkanes; Angiotensin II; Animals; Captopril; Cardiomegaly; Cyclic AMP; Dose-Response Relationship, Drug; Endothelin-1; Hydroxyproline; Isoproterenol; Male; Mice; Myocardium; Myocytes, Cardiac; Organ Size; Rats; Rats, Sprague-Dawley; Sulfites; Thyroxine | 2009 |
Effects of endothelin-1 on the relaxation of rat coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-Agonists; Animals; Coronary Vessels; Endothelin-1; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents; Vasodilation | 2009 |
Proteomics analysis of the cardiac myofilament subproteome reveals dynamic alterations in phosphatase subunit distribution.
Topics: Actin Cytoskeleton; Adrenergic beta-Agonists; Animals; Cells, Cultured; Endothelin-1; Isoproterenol; Male; Mice; Myocardial Contraction; Myocytes, Cardiac; Neurotransmitter Agents; Phosphorylation; Phosphotransferases; Protein Phosphatase 1; Protein Phosphatase 2; Proteome; Proteomics; Rats; Sarcomeres; Tandem Mass Spectrometry | 2010 |
RGS2 inhibits beta-adrenergic receptor-induced cardiomyocyte hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Cell Enlargement; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heart Ventricles; Isoproterenol; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; RGS Proteins; Signal Transduction | 2010 |
Effects of polydatin on attenuating ventricular remodeling in isoproterenol-induced mouse and pressure-overload rat models.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Cardiovascular Agents; Collagen; Cyclic AMP; Drugs, Chinese Herbal; Endothelin-1; Fallopia japonica; Glucosides; Heart; Hypertrophy, Left Ventricular; Isoproterenol; Male; Mice; Myocytes, Cardiac; Organ Size; Phytotherapy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Stilbenes; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2010 |
The IP3 receptor regulates cardiac hypertrophy in response to select stimuli.
Topics: Age Factors; Angiotensin II; Animals; Arrhythmias, Cardiac; Calcineurin; Calcium Signaling; Cardiomegaly; Disease Models, Animal; Endothelin-1; GTP-Binding Protein alpha Subunits, Gq-G11; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoproterenol; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocytes, Cardiac; Phenotype; Physical Exertion | 2010 |
Endothelin-1- and isoproterenol-induced differential protein expression and signaling pathway in HL-1 cardiomyocytes.
Topics: Amino Acid Sequence; Animals; Cardiomegaly; Cardiotonic Agents; Cell Line; Electrophoresis, Gel, Two-Dimensional; Endothelin-1; Gene Expression Regulation; Humans; Isoproterenol; Molecular Sequence Data; Myocytes, Cardiac; Proteins; Signal Transduction; Tandem Mass Spectrometry | 2011 |
Intracellular signaling in human iridial fibroblasts and iridial melanocytes in response to prostaglandins, endothelin, isoproterenol, and other pharmacological agents.
Topics: Cells, Cultured; Chromatography, Ion Exchange; Cyclic AMP; Endothelin-1; Fibroblasts; Humans; Immunoenzyme Techniques; Inositol Phosphates; Iris; Isoproterenol; Melanocytes; Prostaglandins; Receptor, Endothelin A; Receptors, Histamine; Receptors, Prostaglandin; Scintillation Counting; Signal Transduction | 2011 |
Fluorescence resonance energy transfer-based sensor Camui provides new insight into mechanisms of calcium/calmodulin-dependent protein kinase II activation in intact cardiomyocytes.
Topics: Adenoviridae; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Angiotensin II; Animals; Biosensing Techniques; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiac Pacing, Artificial; Endothelin-1; Enzyme Activation; Fluorescence Resonance Energy Transfer; Genetic Vectors; HEK293 Cells; Humans; Isoproterenol; Kinetics; Luminescent Proteins; Microscopy, Confocal; Mutation; Myocytes, Cardiac; Oxidation-Reduction; Phenylephrine; Phosphorylation; Protein Conformation; Protein Processing, Post-Translational; Rabbits; Recombinant Fusion Proteins; Structure-Activity Relationship; Transfection | 2011 |
Regulation of cardiac nitric oxide signaling by nuclear β-adrenergic and endothelin receptors.
Topics: Animals; Endothelin-1; Isoproterenol; Male; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Quinolines; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Adrenergic, beta; Receptors, Endothelin; Signal Transduction | 2013 |
Endocardial endothelium is a key determinant of force-frequency relationship in rat ventricular myocardium.
Topics: Action Potentials; Animals; Calcium; Calcium Signaling; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Endothelin-1; Endothelium, Vascular; Excitation Contraction Coupling; Heart; Heart Rate; Heart Ventricles; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocytes, Cardiac; Protein Kinase C; Rats; Signal Transduction; Trabecular Meshwork | 2013 |
[Effects of ATP-sensitive potassium channel opener iptakalim against ventricular remodeling and its mechanisms of endothelial protection].
Topics: Animals; Endothelin-1; Hemodynamics; Hydroxyproline; Isoproterenol; KATP Channels; Male; Myocardium; Propylamines; Prostaglandins I; Rats; Rats, Wistar; Ventricular Remodeling | 2013 |
Intrinsic-mediated caspase activation is essential for cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; Bronchodilator Agents; Cardiomegaly; Caspase 3; Caspase 9; Cells, Cultured; Cysteine Proteinase Inhibitors; Endothelin-1; Enzyme Activation; Fluorescent Antibody Technique; Hypertrophy; In Vitro Techniques; Isoproterenol; Membrane Potential, Mitochondrial; Myocardium; Myocytes, Cardiac; Oligopeptides; Phenylephrine; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstrictor Agents | 2013 |
Orphan Nuclear Receptor Nur77 Inhibits Cardiac Hypertrophic Response to Beta-Adrenergic Stimulation.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Cardiomegaly; Cells, Cultured; Endothelin-1; GATA4 Transcription Factor; Gene Expression; Gene Expression Regulation; Heart Ventricles; Isoproterenol; Myocytes, Cardiac; NFATC Transcription Factors; Nuclear Receptor Subfamily 4, Group A, Member 1; Phenylephrine; Rats, Sprague-Dawley | 2015 |
Inositol 1,4,5-trisphosphate-mediated sarcoplasmic reticulum-mitochondrial crosstalk influences adenosine triphosphate production via mitochondrial Ca2+ uptake through the mitochondrial ryanodine receptor in cardiac myocytes.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Electric Stimulation; Endothelin-1; Genotype; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoproterenol; Membrane Potential, Mitochondrial; Mice, Transgenic; Mitochondria, Heart; Myocytes, Cardiac; Phenotype; Reactive Oxygen Species; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Time Factors | 2016 |
Caveolin 1 and G-Protein-Coupled Receptor Kinase-2 Coregulate Endothelial Nitric Oxide Synthase Activity in Sinusoidal Endothelial Cells.
Topics: Animals; Caveolin 1; Endothelial Cells; Endothelin-1; G-Protein-Coupled Receptor Kinases; Humans; Isoproterenol; Liver; Male; Mice, Knockout; Models, Biological; Nitric Oxide Synthase Type III; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Domains; Rats, Sprague-Dawley; Receptor, Endothelin B | 2017 |
Connexin 43 Plays a Role in Pulmonary Vascular Reactivity in Mice.
Topics: Animals; Connexin 43; Endothelin-1; Female; Gap Junctions; Genotype; Hypertension, Pulmonary; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Muscle Relaxation; Nitric Oxide; Pulmonary Artery; Real-Time Polymerase Chain Reaction; Serotonin | 2018 |
[Effects of Scrophulariae Radix and Split Component on Isoproterenol-Induced Ventricular Remodeling in Rat].
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Endothelin-1; Isoproterenol; Myocardium; Plant Roots; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2016 |
Cardioprotective effect of the polysaccharide from Ophiopogon japonicus on isoproterenol-induced myocardial ischemia in rats.
Topics: Animals; Antioxidants; Biomarkers; Ca(2+) Mg(2+)-ATPase; Cardiotonic Agents; Catalase; Electrocardiography; Endothelin-1; Glutathione Peroxidase; Isoproterenol; Malondialdehyde; Myocardial Ischemia; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Ophiopogon; Organ Specificity; Polysaccharides; Rats, Sprague-Dawley; Serum Albumin, Human; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2020 |