isoproterenol and cyclosporine

isoproterenol has been researched along with cyclosporine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (25.81)18.2507
2000's14 (45.16)29.6817
2010's9 (29.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Burton, GA; Müller, B; Schmidtke, M1
He, H; Pincus, T; Stein, CM; Wood, AJ1
Kitani, K; Machida, J; Ueda, S; Wada, Y; Yoshida, M1
Goos, M; Jakobs, KH; Nussbaum, G; Ockenfels, HM; Oeljeklaus, P; Schneck, B; Wagner, SN1
Dehpour, AR; Ghafourifar, P; Hassanzadeh, P; Samini, M1
Ichida, T; Obinata, T; Takuma, T; Tamura, S; Yokoyama, N1
Araki, W; Lee, RK; Wurtman, RJ1
Argibay, JA; Malécot, CO; Mijares, A; Peineau, N1
Honda, R; Lalli, MJ; Molkentin, JD; Tymitz, KM; Yatani, A1
Hasegawa, K; Kaburagi, S; Kakita, T; Morimoto, T; Sasayama, S; Wada, H; Yanazume, T1
Domeier, E; Grapow, M; Hakim, K; Janssen, PM; Kögler, H; Milting, H; Prestle, J; Seidler, T; Wangemann, T; Zeitz, O; Zerkowski, HR1
Cattini, PA; Jimenez, SK; Kardami, E; Meij, JT; Nickerson, PW; Sheikh, F1
Zhang, W1
Gilbert, P; Thorin, E1
El-Gowilly, SM; El-Mas, MM; Mohy El-Din, MM; Sharabi, FM1
Chase, EG; Minami, E; Murry, CE; Rossow, CF; Santana, LF1
Clements, JM; Vanhoose, AM; Winder, DG1
Bährle, SK; Christ, T; Marquetant, R; Pena, M; Ravens, U; Schoen, SP; Simonis, G; Strasser, RH1
El-Gowilly, SM; El-Mas, MM; Ghazal, AR; Gohar, EY1
Argani, H; Foroughimoghaddam, H; Ghorbanihaghjo, A; Mesgari, M; Rashtchizadeh, N; Safa, J1
Cattini, PA; Jassal, DS; Jimenez, SK; Kardami, E1
Abd-Elrahman, KS; Abdel-Galil, AG; El-Gowelli, HM; El-Gowilly, SM; El-Mas, MM; Saad, EI1
Antoons, G; Beekman, JD; Bourgonje, VJ; de Windt, LJ; Houtman, MJ; Miedema, LF; Schoenmakers, M; Sipido, K; van der Nagel, R; van Veen, TA; Vos, MA1

Reviews

2 review(s) available for isoproterenol and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Old and new tools to dissect calcineurin's role in pressure-overload cardiac hypertrophy.
    Cardiovascular research, 2002, Feb-01, Volume: 53, Issue:2

    Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Adrenergic beta-Agonists; Animals; Animals, Genetically Modified; Body Weight; Calcineurin; Calcineurin Inhibitors; Carrier Proteins; Cyclosporine; DNA-Binding Proteins; Exercise; Gene Transfer Techniques; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Intracellular Signaling Peptides and Proteins; Isoproterenol; Mice; Models, Animal; Muscle Proteins; Myocardium; Phosphoproteins; Rats; Tacrolimus

2002

Trials

1 trial(s) available for isoproterenol and cyclosporine

ArticleYear
Cyclosporine impairs vasodilation without increased sympathetic activity in humans.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:4

    Topics: Adult; Aged; Alprostadil; Cyclosporine; Dose-Response Relationship, Drug; Female; Hand; Humans; Isoproterenol; Male; Middle Aged; Muscle, Smooth, Vascular; Phenylephrine; Sympathetic Nervous System; Vasodilation; Veins

1995

Other Studies

28 other study(ies) available for isoproterenol and cyclosporine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Iloprost preserves endothelial function against cyclosporin A and sensitises microvessels towards endothelium-dependent and -independent vasodilatation.
    Agents and actions. Supplements, 1992, Volume: 37

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Cheek; Cricetinae; Cyclosporine; Endothelium, Vascular; Iloprost; Isoproterenol; Male; Mesocricetus; Microcirculation; Nitroprusside; Prostaglandin Endoperoxides, Synthetic; Vasoconstrictor Agents; Vasodilation

1992
Effect of cyclosporin A on isolated rabbit bladder and urethral smooth muscle.
    International journal of urology : official journal of the Japanese Urological Association, 1996, Volume: 3, Issue:2

    Topics: Acetylcholine; Animals; Clonidine; Cyclosporine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phenylephrine; Rabbits; Urethra; Urinary Bladder

1996
Inhibition of T cell cAMP formation by cyclosporin A and FK506.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:5

    Topics: Adult; Aged; Colforsin; Cyclic AMP; Cyclosporine; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Isoproterenol; Male; Middle Aged; Psoriasis; T-Lymphocytes; Tacrolimus

1996
The effect of cyclosporine A and trifluoperazine on amylase secretion from rat parotid glands in vitro.
    Fundamental & clinical pharmacology, 1995, Volume: 9, Issue:6

    Topics: Adrenergic beta-Agonists; Amylases; Animals; Cyclosporine; Dopamine Antagonists; Dose-Response Relationship, Drug; Immunosuppressive Agents; Isoproterenol; Male; Parotid Gland; Rats; Rats, Sprague-Dawley; Trifluoperazine

1995
Dephosphorylation of cofilin in parotid acinar cells.
    Journal of biochemistry, 1996, Volume: 120, Issue:1

    Topics: Actin Depolymerizing Factors; Amylases; Animals; Calcimycin; Calcium; Carbachol; Cyclic AMP; Cyclosporine; Enzyme Inhibitors; Exocytosis; Ionophores; Isoproterenol; Marine Toxins; Microfilament Proteins; Nerve Tissue Proteins; Oxazoles; Parotid Gland; Phosphoprotein Phosphatases; Phosphorylation; Rats; Tacrolimus; Tetradecanoylphorbol Acetate

1996
Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, May-13, Volume: 94, Issue:10

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclosporine; Isoproterenol; Kinetics; Norepinephrine; Phosphatidylinositols; Propranolol; Rats; Receptors, Adrenergic, beta; RNA, Messenger; Signal Transduction; Transcription, Genetic

1997
In vivo and in vitro inhibition of the L-type calcium current in isolated guinea-pig cardiomyocytes by the immunosuppressive agent cyclosporin A.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:8

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cyclosporine; Depression, Chemical; Guinea Pigs; Immunosuppressive Agents; Ion Channel Gating; Ion Transport; Isoproterenol; Male; Patch-Clamp Techniques; Phosphorylation; Protein Processing, Post-Translational; Receptors, Adrenergic, beta-1

1997
Enhanced Ca2+ channel currents in cardiac hypertrophy induced by activation of calcineurin-dependent pathway.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:2

    Topics: Animals; Blotting, Western; Calcineurin; Calcineurin Inhibitors; Calcium; Calcium Channels; Cardiomegaly; Cyclosporine; Electrophysiology; Isoproterenol; Kinetics; Mice; Mice, Transgenic; Myocardium; Protein Structure, Tertiary; Ryanodine

2001
Calcineurin-GATA4 pathway is involved in beta-adrenergic agonist-responsive endothelin-1 transcription in cardiac myocytes.
    The Journal of biological chemistry, 2001, Sep-14, Volume: 276, Issue:37

    Topics: Adrenergic beta-Agonists; Animals; Calcineurin; Cyclosporine; DNA-Binding Proteins; Endothelin-1; GATA4 Transcription Factor; Isoproterenol; Myocardium; NFATC Transcription Factors; Norepinephrine; Nuclear Proteins; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Transcription Factors; Transcription, Genetic

2001
FK506 does not affect cardiac contractility and adrenergic response in vitro.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Adrenergic beta-Agonists; Animals; Atrial Function; Cyclosporine; Dose-Response Relationship, Drug; Heart Atria; Heart Ventricles; Humans; Immunosuppressive Agents; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Rabbits; Tacrolimus; Ventricular Function

2001
Exacerbation of myocardial injury in transgenic mice overexpressing FGF-2 is T cell dependent.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2

    Topics: Animals; Antibodies, Monoclonal; CD3 Complex; Cyclosporine; Female; Fibroblast Growth Factor 2; Gene Expression; Heart Diseases; Immunosuppressive Agents; Isoproterenol; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Myocardium; Receptors, Antigen, T-Cell; Sympathomimetics; T-Lymphocytes

2002
Endothelin-1 limits vascular smooth muscle beta-adrenergic receptor sensitivity by a PKC-dependent pathway.
    Journal of cardiovascular pharmacology, 2003, Volume: 42, Issue:4

    Topics: Alkaloids; Animals; Aorta, Thoracic; Benzophenanthridines; Colforsin; Cyclosporine; Endothelin Receptor Antagonists; Endothelin-1; Female; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenanthridines; Phenylephrine; Protein Kinase C; Rabbits; Receptors, Adrenergic, beta; Receptors, Endothelin; Vasodilation

2003
Relative roles of endothelial relaxing factors in cyclosporine-induced impairment of cholinergic and beta-adrenergic renal vasodilations.
    European journal of pharmacology, 2004, Mar-08, Volume: 487, Issue:1-3

    Topics: Acetylcholine; Animals; Arginine; Biological Factors; Cyclooxygenase Inhibitors; Cyclosporine; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Parasympathetic Nervous System; Phenylephrine; Potassium Channel Blockers; Prostaglandins; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Renal Circulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2004
NFATc3-induced reductions in voltage-gated K+ currents after myocardial infarction.
    Circulation research, 2004, May-28, Volume: 94, Issue:10

    Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclosporine; DNA-Binding Proteins; Electric Conductivity; Isoproterenol; Kinetics; Metoprolol; Mice; Mice, Knockout; Myocardial Infarction; Myocytes, Cardiac; NFATC Transcription Factors; Potassium Channels, Voltage-Gated; Transcription Factors

2004
Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jan-25, Volume: 26, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcineurin Inhibitors; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Marine Toxins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxazoles; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperidines; Protein Phosphatase 1; Protein Phosphatase 2; Protein Processing, Post-Translational; Receptors, Adrenergic, beta-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2006
Receptor-independent sensitization of the adenylyl cylase after chronic treatment with cyclosporine A.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:3

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Arrestin; beta-Adrenergic Receptor Kinases; Cell Membrane; Cyclosporine; Gene Expression Regulation, Enzymologic; Heart; Immunosuppressive Agents; In Vitro Techniques; Isoproterenol; Lung; Male; Myocardial Contraction; Radioligand Assay; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Receptors, G-Protein-Coupled; Receptors, Muscarinic

2008
Exacerbation by nicotine of the cyclosporine A-induced impairment of beta-adrenoceptor-mediated renal vasodilation in rats.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:10

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Kidney; Kidney Function Tests; Male; Nicotine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Vasodilation; Vasodilator Agents

2008
Effect of isoproterenol on cyclosporine-induced nephrotoxicity in rat.
    Transplantation proceedings, 2008, Volume: 40, Issue:10

    Topics: Animals; Antioxidants; Creatinine; Cyclosporine; Isoproterenol; Kidney; Male; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Urea

2008
Protection by endogenous FGF-2 against isoproterenol-induced cardiac dysfunction is attenuated by cyclosporine A.
    Molecular and cellular biochemistry, 2011, Volume: 357, Issue:1-2

    Topics: Adrenergic beta-Agonists; Animals; Cyclosporine; Fibroblast Growth Factor 2; Isoproterenol; Mice; Mice, Transgenic; Ultrasonography, Doppler; Ventricular Dysfunction

2011
PPARγ dependence of cyclosporine-isoprenaline renovascular interaction: roles of nitric oxide synthase and heme oxygenase.
    Journal of cardiovascular pharmacology, 2011, Volume: 58, Issue:2

    Topics: Animals; Cyclosporine; Drug Interactions; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Isoproterenol; Kidney; Male; Nitric Oxide Synthase; Pioglitazone; PPAR gamma; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Thiazolidinediones; Vasodilation

2011
Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog.
    Heart rhythm, 2012, Volume: 9, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Atrioventricular Block; Benzylamines; Calcineurin; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomyopathy, Hypertrophic; Cyclosporine; Disease Models, Animal; Dogs; Isoproterenol; Long QT Syndrome; Myocytes, Cardiac; Patch-Clamp Techniques; Phenethylamines; Phenotype; Phosphorylation; Random Allocation; Sulfonamides; Ventricular Remodeling

2012