isoproterenol has been researched along with cyclic gmp in 471 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 237 (50.32) | 18.7374 |
| 1990's | 154 (32.70) | 18.2507 |
| 2000's | 59 (12.53) | 29.6817 |
| 2010's | 17 (3.61) | 24.3611 |
| 2020's | 4 (0.85) | 2.80 |
| Authors | Studies |
|---|---|
| Ghanbari, H; McCarl, RL | 1 |
| O'Dea, RF; Zatz, M | 1 |
| Norwood, CW | 1 |
| Ito, M; Parrott, DM; Sless, F | 1 |
| Laudat, MH; Lecot, F; Levilliers, J; Pairault, J; Tournemolle, A | 1 |
| Brooker, G; Harper, JF | 2 |
| Hamilton, J; Horwitz, BA | 1 |
| Potter, DE; Rowland, JM | 1 |
| Andrews, JL; Webb-Johnson, DC | 1 |
| Hofbauer, KG; Konrads, A; Schwarz, K; Werner, U | 1 |
| Andersson, RG; Brundin, A; Lindgren, BR | 1 |
| Brown, BS; Krzanowski, JJ; Polson, JB | 1 |
| Fleisch, JH; Hooker, CS; Schmidt, MJ; Spaethe, SM; Truex, LL | 1 |
| Eyre, P; Perron, RJ | 1 |
| Schreiner, GF; Unanue, ER | 1 |
| Galant, SP; Remo, RA | 1 |
| Arnold, A; Butcher, FR; Fain, JN; Pointer, RH; Tolbert, ME | 1 |
| Butcher, FR | 1 |
| Estensen, RD; Goldberg, ND; Hill, HR; Hogan, NA; Quie, PG | 1 |
| Andersson, R; Johansson, S; Lundholm, L; Mohme-Lundholm, E; Nilsson, K; Wikberg, J | 1 |
| Greengard, P | 1 |
| Ackerman, NR; Beebe, JR | 1 |
| Denniss, AR; Young, JA | 1 |
| Besch, HR; Watanabe, AM | 1 |
| Byron, JW | 2 |
| Granger, GA; Prieur, AM | 1 |
| Berl, T; Harbottle, JA; McDonald, KM; Schrier, RW | 1 |
| Grand, RJ; Kimberg, DV; Wojcik, JD | 1 |
| Roukema, PA; Vreugdenhil, AP | 1 |
| Edström, A; Kanje, M; Löfgren, P; Walum, E | 1 |
| Kondo, S; Schulz, I | 1 |
| Busuttil, RW; George, WJ; Ignarro, LJ; Paddock, RJ; White, LA | 1 |
| Claus, TH; Pilkis, SJ | 1 |
| Huot, J; Jard, S; Penit, J | 1 |
| Berkowitz, BA; Cohen, ML | 1 |
| Ohkubo, H; Takagi, K; Takayanagi, I | 1 |
| Thomas, JA; Zepp, EA | 1 |
| Butcher, FR; Fain, JN; Pointer, RH | 1 |
| George, WJ; Ignarro, LJ; Kadowitz, PJ; Paddock, RJ; White, L | 1 |
| Jacob, R; Schwegler, M | 1 |
| Azuma, H; Maruyama, HB | 1 |
| Bhoola, KD; Heap, PF; Lemon, MJ | 1 |
| Goel, Z; Grieco, MH; Siegel, I | 1 |
| Birnbaum, MJ; Fain, JN; Schultz, J | 1 |
| Claycomb, WC | 1 |
| Craven, PA; DeRubertis, FR | 2 |
| Davis, BB; Zenser, TV | 1 |
| Camus, J; Christophe, J; Lambert, M | 1 |
| Albano, J; Bhoola, KD; Heap, PF; Lemon, MJ | 1 |
| Jaeger, V; Kunos, G; Mucci, L | 1 |
| Capps, MJ; Itzhaki, S | 1 |
| England, PJ | 1 |
| Christoffersen, T; Wisloff, F | 1 |
| Deth, R; van Breemen, C | 1 |
| Brascher, HK; Ferreira, GG; Javierre, MQ; Lima, AO; Sassine, WA | 1 |
| Astrup, EG; Boutwell, RK; Mufson, RA; Simsiman, RC | 1 |
| Durham, JP; Galanti, N | 1 |
| Atkins, D; Hunt, NH; Ingleton, PM; Martin, TJ | 1 |
| Hatch, GE; Hill, HR; Nichols, WK | 1 |
| Ruoff, HJ | 1 |
| Kaliner, M | 1 |
| Horn, JP; McAfee, DA | 1 |
| Corbin, JD; Keely, SL; Lincoln, T | 1 |
| Antunes, LJ; Machado, JA; Silva, EN | 1 |
| Bendtzen, K; Palit, J | 1 |
| Hadden, JW; Kurland, JI; Moore, MA | 1 |
| Brodde, OE; Endoh, M; Motomura, S; Schümann, HJ | 1 |
| Anderson, WH; Krzanowski, JJ; Lust, WD; Polson, JB; Szentivanyi, A | 1 |
| Flitney, FW; Lamb, JF; Singh, J | 1 |
| Boyse, EA; Goldstein, G; Scheid, MP | 1 |
| Brackett, NL; Kuo, JF; Tse, J | 1 |
| Haap, K; Kohlhardt, M | 1 |
| Cinader, B; Dubiski, S; Emin, M | 1 |
| Neufeld, AH | 1 |
| McNeill, JH; Meisheri, KD; Tenner, TE | 1 |
| Zatz, M | 1 |
| Breckenridge, BM; Kon, C | 1 |
| Endoh, M; Honma, M | 1 |
| Giri, SN; Hollinger, MA | 1 |
| Brown, JH | 1 |
| Endoh, M; Shimizu, T | 1 |
| Asakura, K; Kataura, A | 1 |
| Clyman, RI; Manganiello, VC; Sandler, JA; Vaughan, M | 1 |
| Costa, E; Guidotti, A; Hanbauer, I | 1 |
| Costa, E; Guidotti, A; Hanbauer, I; Kopin, IJ | 1 |
| Noma, A; Ono, K; Tareen, FM; Yoshida, A | 1 |
| Colbran, JL; Corbin, JD; Francis, SH; Jiang, H | 1 |
| Akita, H; Hirata, K; Watanabe, Y; Yokoyama, M | 1 |
| Agli, B; Giudicelli, Y; Lacasa, D | 1 |
| Miyata, N; Otomo, S; Tsuchida, K; Yamaura, H | 1 |
| Chik, CL; Girard, M; Ho, AK; O'Brien, L | 1 |
| Gray, DW; Marshall, I | 1 |
| Dokita, S; Morita, T; Tsujii, T | 1 |
| Förstermann, U; Helgren, MC; Kimber, ND; Klabunde, RE; Kuk, JE | 1 |
| Belfrage, P; Ekholm, D; Lafontan, M; Langin, D; Ridderstråle, M | 1 |
| Iga, T; Maeno, N | 1 |
| Bennett, BM; Long, PG; McDonald, BJ; Nigam, R; Simon, WC | 1 |
| Belfrage, P; Degerman, E; Manganiello, VC; Smith, CJ; Vasta, V | 1 |
| Chik, CL; Ho, AK; Young, I | 1 |
| Chik, CL; Girard, M; Ho, AK; Young, I | 1 |
| Bast, A; Leurs, R; Timmerman, H | 1 |
| Bellan, JA; Hood, JS; Kadowitz, PJ; McMahon, TJ | 1 |
| Buchan, KW; Martin, W | 1 |
| Roberts, JM; Russell, JA | 1 |
| Adolfs, MJ; Bonta, IL; Houdijk, AP; Van Leeuwen, PA | 1 |
| Ono, K; Trautwein, W | 1 |
| Sugden, D | 2 |
| Torphy, TJ; Zhou, HL | 1 |
| Lugnier, C; Muller, B; Stoclet, JC | 1 |
| Henderson, AH; Lewis, MJ; Shah, AM | 1 |
| Andersson, TL; Vinge, E | 1 |
| Sperelakis, N; Tripathi, O | 1 |
| Busse, R; Jackson, WF; Mülsch, A | 1 |
| Fineman, JR; Heymann, MA; Soifer, SJ | 1 |
| Bataille, D; Blache, P; Brechler, V; Kervran, A; Laurent, S; Le-Nguyen, D; Pavoine, C; Pecker, F | 1 |
| Haslam, RJ; Maurice, DH | 1 |
| Belfrage, P; Degerman, E; Manganiello, VC; Smith, CJ; Tornqvist, H; Vasta, V | 1 |
| Barsony, J; Marx, SJ | 1 |
| Diamond, J; Giembycz, MA | 1 |
| de Jonge, HR; de Vente, J; Esterbauer, H; Koster, JF; Steinbusch, HW; van der Kraaij, AM | 1 |
| Chik, CL; Cragoe, EJ; Ho, AK; Lalh, SS; Young, I | 1 |
| Brinker, MR; Cook, SD; Hyman, AL; Lippton, HL | 1 |
| Cherry, PD; Farrell, KA; Omar, HA; Stuart, JS; Wolin, MS | 1 |
| Stuart-Smith, K; Vanhoutte, PM | 1 |
| Koch, G; Kort, JJ | 1 |
| Hechtman, HB; Morel, NM; Petruzzo, PP; Shepro, D | 1 |
| Brückner, R; Gramann, S; Nose, M; Schmitz, W; Scholz, H | 1 |
| Alberts, P; Ogren, VR; Sellström, AI | 1 |
| Jacobson, KL; Singh, JC; Watson, EL | 1 |
| Heisler, S | 1 |
| Furchgott, RF; Jothianandan, D; Martin, W; Villani, GM | 2 |
| Cassity, N; Martinez, JR | 1 |
| Cline, WH; Nickols, GA | 1 |
| Athias, P; Ettaiche, M; Variot, N | 1 |
| Hartzell, HC; Simmons, MA | 1 |
| Ishii, K; Murad, F | 1 |
| Hyman, AL; Kadowitz, PJ; Lippton, HL | 1 |
| Briand, V; Lacolley, P; Laurent, S; Michel, JB; Schmitt, H; Vaxelaire, JF | 1 |
| Kotecha, N; Neild, TO | 1 |
| Rodger, IW; Shahid, M | 2 |
| Ishikawa, S; Sperelakis, N | 1 |
| Bassenge, E; Busse, R; Mülsch, A; Pohl, U | 1 |
| Boyes, S; Loten, EG | 1 |
| Ando, S; Hirooka, Y; Imaizumi, T; Nakamura, M; Suzuki, S; Takeshita, A; Yoshida, M | 1 |
| Flanagan, JE; Kono, T; Robinson, FW; Shibata, H; Smith, CJ | 1 |
| Bizec, JC; Klethi, J; Mandel, P | 1 |
| Johns, RA; Linden, JM; Peach, MJ | 1 |
| Anderson, NG; Houslay, MD; Kilgour, E | 1 |
| Dokita, S | 1 |
| Bkaily, G; Sperelakis, N | 1 |
| Chik, CL; Ho, AK; Klein, DC | 3 |
| Demesy-Waeldele, F; Lugnier, C; Schoeffter, P; Stoclet, JC | 1 |
| Ousterhout, JM; Sperelakis, N | 1 |
| Franco-Saenz, R; Mulrow, PJ; Takagi, M | 1 |
| Sperelakis, N; Thakkar, JK | 1 |
| Agnati, LF; Benfenati, F; Cattabeni, F; Cimino, M; Farabegoli, C | 1 |
| Clark, CL; Taylor, MJ | 1 |
| Chapnick, BM; Ohlstein, EH; Secrest, RJ | 1 |
| Frambach, DA; Valentine, JL; Weiter, JJ | 1 |
| Linz, W; Schölkens, BA; Wiemer, G | 1 |
| Dusting, GJ; Grace, GC; Macdonald, PS | 1 |
| Burman, M; Huang, LB; Torphy, TJ; Tucker, SS | 1 |
| Johnson, GV | 1 |
| Sperelakis, N; Tang, SB; Thakkar, J; Wahler, GM | 1 |
| Ecker, T; Felbel, J; Hofmann, F; Landgraf, W; Trockur, B | 1 |
| Khullar, AK; Schwarz, V; Wilson, PD | 1 |
| MacLeod, KM | 1 |
| Campbell, WB; Henrich, WL; McAllister, EA; Smith, PB | 1 |
| Kagamimori, S; Kakiuchi, H; Naruse, Y; Shimizu, T; Williams, WR | 1 |
| Levy, BD; Madaras, JG; Mecham, RP; Morris, SL; Wrenn, DS | 1 |
| Bowman, WC; Lam, FY; Rodger, IW; Shahid, M | 1 |
| Itoh, T; Kanmura, Y; Kuriyama, H; Sasaguri, T | 1 |
| Lu, DY | 1 |
| Demura, H; Inagami, T; Naruse, K; Naruse, M; Obana, K; Sakurai, H; Shizume, K | 1 |
| Butz, JJ; Hink, WF | 1 |
| Endoh, M; Iijima, T; Maruyama, M | 1 |
| Gilmour, RF; Zipes, DP | 1 |
| Chander, A; Dodia, C; Fisher, AB | 1 |
| Obara, K; Yamada, T | 1 |
| Butera, L; Dusting, GJ; Kubota, M; MacDonald, PS; Martin, TJ; Moseley, JM | 1 |
| Dobson, JG; Murray, JJ; Reed, PW | 1 |
| Connelly-Fittingoff, M; Fernandez, EI; Krall, JF | 1 |
| Klein, DC; Sugden, D; Vanecek, J; Weller, JL | 1 |
| Kimura, A; Nakagawa, H; Ohuchi, T; Oka, M | 1 |
| Klein, DC; Sugden, AL; Sugden, D | 1 |
| Barnette, MS; Burman, M; Fine, CF; Ormsbee, HS; Torphy, TJ | 1 |
| Barnette, MS; Miller, CA; Ormsbee, HS; Torphy, TJ | 1 |
| Nolte, JF; Rubin, LJ | 1 |
| Böhme, E; Jakobs, KH; Mocikat, S | 1 |
| Manganiello, VC; Stoner, JS; Vaughan, M | 1 |
| Bosch, AL; Clark, MG; Kneer, NM; Lardy, HA | 1 |
| Amer, MS; Ferguson, HC; Gomoll, AW; McKinney, GR; Perhach, JL | 1 |
| Costa, E; Guidotti, A; Mao, CC | 1 |
| Murad, F | 1 |
| Friedmann, N; Somlyo, AP; Somlyo, AV | 1 |
| Erlichman, J; Goren, EN; Rosen, OM; Rosen, SM | 1 |
| Böhme, E; Jakobs, KH; Schultz, G; Schultz, K | 1 |
| Barish, J; Ensinck, JW; Williams, RH | 1 |
| Donnelly, TE; Greengard, P; Kuo, JF; Lee, TP; Reyes, PL; Walton, KG | 1 |
| Greengard, P; Kuo, JF; Lee, TP | 1 |
| Hess, SM; Michel, IM; Weinryb, I | 1 |
| Hillman, GR; Senft, AW | 1 |
| Austen, KF; Carpenter, CB; Garovoy, MR; Kaliner, M; Merrill, JP; Strom, TB | 1 |
| Ignarro, LJ; Krassikoff, N; Slywka, J | 1 |
| Fudenberg, HH; Luong, D; Perlman, JD; Stites, DP; Webb, DR | 1 |
| Kuo, JF; Kuo, WN | 1 |
| Hoffstein, S; Kammerman, S; Tai, HH; Weissmann, G; Zurier, RB | 1 |
| Manganiello, VC; Stoner, J; Vaughan, M | 1 |
| Hoffstein, S; Weissmann, G; Zurier, RB | 1 |
| Dunham, EW; Goldberg, ND; Haddox, MK | 1 |
| Diamond, J; Hartle, DK | 1 |
| Baserga, R; Butcher, FR; Durham, JP | 1 |
| Butcher, FR; Durham, JP | 1 |
| Gale, RP; Zighelboim, J | 1 |
| Chader, GJ; Fletcher, RT; Herz, L | 1 |
| Schrier, RW | 1 |
| Pazdernik, TL; Uyeki, EM | 1 |
| Ball, JH; Broadus, AE; Hardman, JG; Kaminsky, NI; Liddle, GW; Sutherland, EW | 1 |
| Brown, JH; Masters, SB | 1 |
| Böhm, M; Brückner, R; Hackbarth, I; Haubitz, B; Linhart, R; Meyer, W; Schmidt, B; Schmitz, W; Scholz, H | 1 |
| Bellamy, PE; Tierney, DF | 1 |
| Lishmanov, IuB; Pavlenko, VS; Slepushkin, VD; Titov, MI; Zoloev, GK | 1 |
| Ishihara, Y; Kitamura, S; Kosaka, K; Yotsumoto, H | 1 |
| Catena, FB; Lombardi, L; Maiolo, AT; Peracchi, M; Polli, EE | 1 |
| D'Ascenzo, G; Gennari, C; Maioli, E; Nami, R; Nardi, PL; Pizzuti, M | 1 |
| Greengard, P; Nestler, EJ; Zata, M | 1 |
| Dowd, F; Watson, EL | 1 |
| Boat, TF; Liedtke, CM; Rudolph, SA | 1 |
| DoKhac, L; Harbon, S; Leiber, D; Tanfin, Z; Vesin, MF | 1 |
| Brown, BS; Krzanowski, JJ; Polson, JB; Wiggins, JR | 1 |
| Andersson, RG; Börjesson, S; Nilsson, KB | 1 |
| Dowd, F; Jacobson, KL; Watson, EL | 1 |
| Dowd, F; Horwitz, H; Jacobson, K; Watson, E | 1 |
| Bilan, PT; Fleming, N; Graham, KW | 1 |
| Exton, JH | 2 |
| Kuo, HS; Sanborn, BM; Sherwood, OD; Weisbrodt, NW | 1 |
| Perchellet, JP; Sharma, RK | 1 |
| Chaplin, DD; Parker, CW; Wedner, HJ | 1 |
| Ferreira, SH | 1 |
| Kuo, JF; Tse, J; Wrenn, RW | 1 |
| Carpenter, CB; Strom, TB | 1 |
| Endoh, M | 1 |
| Conolly, ME | 1 |
| Hata, S; Honma, M; Ide, H; Kunitada, S; Okada, F; Satoh, T; Ui, M | 1 |
| Cottam, GL; Ishibashi, H; McCully, V; Nagano, M | 1 |
| Allen, DO; Ingebretsen, CG; Rabin, RA | 1 |
| Ingebretsen, CG | 1 |
| Brooker, G; Linden, J | 1 |
| Brown, LA; Longmore, WJ | 1 |
| Badenoch-Jones, P; Larno, S; Rouveix, B; Turk, JL | 1 |
| Baur, S; Grant, B; Wooton, J | 1 |
| Argel, M; Chiappe, L; Cingolani, HE; Grassi, A; Vittone, L | 1 |
| Gross, SR; Kelly, M | 1 |
| Costa, E; Hanbauer, I; Onali, P; Schwartz, JP | 1 |
| Boerth, RC; Mushlin, P; Wells, JN | 2 |
| Metsä-Ketelä, T; Parantainen, J; Vapaatalo, H | 1 |
| Cailleau, J; de Moor, P; Verhoeven, G | 1 |
| Alonso, F; Mato, JM; Sánchez-Crespo, M | 1 |
| Belman, S; Garte, SJ | 1 |
| Fauci, AS; Katz, P; Zaytoun, AM | 1 |
| Endoh, M; Taira, N; Yamashita, S | 1 |
| Coutu, MD; Hartigan, PM; Pappano, AJ | 1 |
| Ciccone, J; Garay, RP | 1 |
| Wojtczak, J | 1 |
| Champion, S; Mauchamp, J | 1 |
| Eisner, GM; Jose, PA; Pelayo, JC; Slotkoff, LM; Wargo, AA | 1 |
| Lorenz, KL; Wells, JN | 1 |
| Jensen, A; Puckett, AM; Rinard, GA | 1 |
| Bijman, J; Quinton, PM | 1 |
| Giles, WR; Han, X; Shimoni, Y | 1 |
| Satoh, K; Taira, N; Yamagishi, T; Yanagisawa, T | 1 |
| Frelin, C; Lund, L; Vigne, P | 1 |
| Imai, A; Nashida, T; Shimomura, H | 1 |
| Ashikaga, T; Kishi, Y; Numano, F; Watanabe, R | 1 |
| Chik, CL; Ho, AK; Murdoch, G; Ogiwara, T | 1 |
| Chik, CL; Ho, AK | 1 |
| Armstead, WM; Devine, JO; Rebich, S | 1 |
| Noma, A; Ono, K | 1 |
| Cushman, SW; Manganiello, VC; Omatsu-Kanbe, M; Taira, M | 1 |
| Maronde, E; Mayer, B; Middendorff, R; Olcese, J | 1 |
| Boucher, RC; Davis, CW; Geary, CA; Paradiso, AM | 1 |
| Eichholtz-Wirth, H | 1 |
| Deschepper, CF; Gonçalves, J; Grove, KL | 1 |
| Abel, FL; Lader, AS; Phillips, GC; Starr, RG; Stroman, CE | 1 |
| Dietz, R; Haase, H; Karczewski, P; Krause, EG; Sabine, B; Wallukat, G; Willenbrock, R | 1 |
| Balligand, JL; Kelly, RA; Marsden, PA; Michel, T; Smith, TW | 1 |
| Eckly, AE; Lugnier, C; Stoclet, JC | 1 |
| Castresana, MR; Newman, WH; Zhang, LM | 1 |
| Inoue, M; Morikawa, M; Satake, N; Shibata, S; Zhou, Q | 1 |
| Castresana, MR; Newman, WH; Shillcutt, SD; Tao, H; Zhang, LM | 1 |
| Campbell, DN; Fullerton, DA; Grover, FL; McIntyre, RC; Mitchell, MB | 1 |
| Bénardeau, A; Fischmeister, R; Hatem, S; Kirstein, M; Mercadier, JJ; Rivet-Bastide, M | 1 |
| Agrafojo, J; Banerjee, A; Fullerton, DA; Hahn, AR; McIntyre, RC | 1 |
| Daniel, EE; Eng, R; Hipworth, S; Lu, S; McGrogan, I; Preocanin, D; Sormaz, L | 1 |
| Belhassen, L; Fischmeister, R; Méry, PF; Pavoine, C; Pecker, F | 1 |
| Banerjee, A; Fullerton, DA; Hahn, AR; Harken, AH | 1 |
| Satake, N; Shibata, S; Zhou, Q | 1 |
| Itoh, H; Kishimoto, I; Komatsu, Y; Nakagawa, O; Nakao, K; Ogawa, Y; Suga, S; Yoshimasa, T | 1 |
| Earm, YE; Han, J; Ho, W; Hong, S; Kim, E; Leem, C; So, I; Sung, H | 1 |
| de Wit, C; Pohl, U; von Bismarck, P | 1 |
| Béa, ML; Berdeaux, A; Ghaleh, B; Giudicelli, JF | 1 |
| Brown, JM; Campbell, DN; Fullerton, DA; Grover, FL; McIntyre, RC; Meng, X; Mitchell, MB | 1 |
| Klein, DC; White, BH | 1 |
| Dickinson, K; Foster, GA; Frodsham, G; Jones, RB | 1 |
| Crankshaw, D; Davidson, MM; Haslam, RJ; Jang, EK | 1 |
| Hume, JR; Ishikawa, T; Keef, KD | 1 |
| Li, KX; Sperelakis, N | 1 |
| Nakashima, Y; Ono, K; Shioya, T | 1 |
| Bartel, S; Karczewski, P; Krause, EG | 1 |
| Miyata, N; Otomo, S; Takahashi, K; Tanaka, M; Tsuchida, K; Yamaura, H | 1 |
| Haslam, RJ; Lee, RM; Maurice, DH | 1 |
| Hori, M; Karaki, H; Kwon, SC; Ozaki, H | 1 |
| Kurtz, A; Scholz, H | 1 |
| Grider, JR; Jin, JG; Makhlouf, GM; Murthy, KS | 1 |
| Grider, JR; Makhlouf, GM; Murthy, KS; Severi, C | 1 |
| Heiny, JA; Kokate, TG; Sperelakis, N | 1 |
| Boyle, JP; Challiss, RA; Ijioma, SC | 1 |
| Fullerton, DA; Jones, DN; Maki, A; McIntyre, RC; Mitchell, MB | 1 |
| Alberdi, E; Castiella, E; Cenarruzabeitia, E; Frechilla, D; Lasheras, B; Martínez de Irujo, JJ; Martinez, FJ; Monge, A; Santiago, E; Villanueva, A | 1 |
| Böhm, M; Flesch, M; Kilter, H; Kuhn-Regnier, F; La Rosée, K; Lenz, O; Mädge, M; Schwinger, RH | 1 |
| Diamond, J; MacDonell, KL; Tibbits, GF | 1 |
| Garcia, R; Lacasse, A; Thibault, G | 1 |
| Agrafojo, J; Fullerton, DA; Hahn, AR; McIntyre, RC; Sheridan, BC | 1 |
| Bell, DR; Dec, EM; Rensberger, HJ | 1 |
| Ebihara, Y; Karmazyn, M | 1 |
| Coste, H; Delpy, E; Gouville, AC | 1 |
| Anfossi, G; Cavalot, F; Hahn, AW; Massucco, P; Mattiello, L; Mularoni, EM; Trovati, M | 1 |
| Baudouin, B; Géniteau-Legendre, M; Millul, V; Prié, D; Ronco, PM; Verpont, MC | 1 |
| Guo, X; Kedem, J; Scholz, PM; Weiss, HR | 1 |
| Pappano, AJ; Shirayama, T | 1 |
| Hill, G; Spessert, R; Vollrath, L | 1 |
| Hashizume, Y; Nasa, Y; Ohaku, H; Sanbe, A; Takeo, S; Toyoshima, H | 1 |
| Balligand, JL; Colucci, WS; Hare, JM; Keaney, JF; Loscalzo, J; Smith, TW | 1 |
| Ito, H; Kurachi, Y; Tada, Y; Tsuchimochi, H | 1 |
| Ito, M; Naruse, A; Satake, N; Shibata, S; Suzuki, Y; Yamamoto, I | 1 |
| Arana, R; Bacman, S; Borda, E; Camusso, JJ; Hubscher, O; Sterin-Borda, L | 1 |
| Brizzolara-Gourdie, A; Webb, JG | 1 |
| Crilley, CT; Garcia, R | 1 |
| Alexander, SP; Hernández, F; Kendall, DA; Neil, KE | 1 |
| Cobbe, SM; Kane, KA; Martynyuk, AE; Rankin, AC | 1 |
| Cheng, K; Christodoulides, N; Durante, W; Peyton, KJ; Schafer, AI; Sunahara, RK | 1 |
| Amaral, J; Behar, J; Biancani, P; Chen, Q; Oh, S | 1 |
| Eckly-Michel, A; Lugnier, C; Martin, V | 1 |
| Naim, KL; Rabindranauth, P; Scholz, PM; Tse, J; Weiss, HR | 1 |
| Fullerton, DA; McIntyre, RC; Meldrum, DR; Sheridan, BC | 1 |
| Franklin, A; Hariawala, MD; Li, J; Sellke, FW; Stamler, A; Tofukuji, M | 1 |
| Klabunde, RE; Sadoff, JD; Scholz, PM; Weiss, HR | 1 |
| Diamond, J; MacDonell, KL | 1 |
| Förstermann, U; Gath, I; Nawrath, H; Wegener, JW | 1 |
| Earm, YE; Han, J; Ho, WK; Kim, E; Lee, SH; Yoo, S | 1 |
| Isayama, Y; Kohsaka, Y; Nasa, Y; Sanbe, A; Takeo, S; Toyoshima, H; Yamaguchi, F | 1 |
| Higuchi, S; Nakasone, C; Noguchi, K; Shigenobu, K; Shijuku, T; Takahashi, K; Tanaka, H; Tanaka, Y | 1 |
| Chik, CL; Ho, AK; Negishi, T | 1 |
| Balligand, JL; Joe, EK; Kelly, RA; Longrois, D; Mäki, T; Schussheim, AE; Smith, TW | 1 |
| Jacobson, KL; Ott, SM; Singh, JC; Storm, DR; Watson, EL; Wu, Z | 1 |
| Borda, E; Cremaschi, G; Genaro, A; Perez Leiros, C; Sterin-Borda, L; Vila Echagüe, A | 1 |
| Adachi, R; Brody, JS; Dickey, BF; Joyce-Brady, M; Oakes, SM; Panchenko, MP; Starikova, MG | 1 |
| Bianciotti, LG; di Carlo, MB; Elverdin, JC; Fernandez, BE; Negri, G; Vatta, MS | 1 |
| Ikezaki, H; Onyüksel, H; Rubinstein, I | 1 |
| Bartunek, J; Dempsey, S; Ito, N; Lorell, BH; Rohrbach, S; Tajima, M; Weinberg, EO | 1 |
| May, K; Sisson, JH; Spurzem, JR; Wyatt, TA | 1 |
| Balligand, JL; Bril, A; Gauthier, C; Khandoudi, N; Kobzik, L; Le Marec, H; Leblais, V; Trochu, JN | 1 |
| von der Weid, PY | 1 |
| Hashizume, Y; Isayama, Y; Kohsaka, Y; Koseki, Y; Nasa, Y; Takeo, S; Toyoshima, H; Yamada, T | 1 |
| Adnot, S; Eddahibi, S; Le Monnier de Gouville, AC; Raffestin, B | 1 |
| Schenda, J; Vollrath, L | 1 |
| Boev, KK; Fusi, F; Petkov, GV; Sgaragli, GP; Valoti, M | 1 |
| Makhlouf, GM; Murthy, KS | 1 |
| Chik, CL; Ho, AK; Karpinski, E; Li, B | 1 |
| Flavahan, NA; Horibe, M; Murray, PA; Smedira, NG; Yoshida, K | 1 |
| Leone, RJ; Naim, KL; Rabindranauth, P; Scholz, PM; Tse, J; Weiss, HR | 1 |
| Arai, M; Kanda, T; Nagai, R; Sekiguchi, K; Suzuki, T; Tanaka, T; Yokoyama, T | 1 |
| Fukuchi, Y; Kira, S; Muramatsu, M; Ohnishi, M; Oka, M; Sato, K | 1 |
| Diamond, J; Sandirasegarane, L | 2 |
| Potter, DE; Thompson, WJ; Zhou, L | 2 |
| Berdeaux, A; Bévérelli, F; Gauthier, C; Le Marec, H; Leblais, V; Rautureau, Y; Trochu, JN | 1 |
| Brusq, JM; Guigui, L; Kirilovsky, J; Mayoux, E | 1 |
| Berman, J; Goldstein, I; Huang, YH; Kim, NN; Moreland, RB; Traish, A | 1 |
| Tabrizchi, R | 1 |
| Dormer, RL; Lloyd Mills, C; McPherson, MA; Murray, KJ; Pereira, MM | 1 |
| Brunton, LL; Endo-Mochizuki, Y; Gonzalez, AM; Meszaros, JG; Villarreal, F; Villegas, S | 1 |
| Leone, RJ; Scholz, PM; Straznicka, M; Weiss, HR | 1 |
| Chik, CL; Ho, AK; Karpinski, E; Li, B; Negishi, T | 1 |
| He, YQ; Huang, MW; Leone, RJ; Scholz, PM; Tse, J; Weiss, HR | 1 |
| de Cingolani, GC; Mattiazzi, A; Mundiña-Weilenmann, C; Rinaldi, G; Said, M; Vittone, L | 1 |
| Berlan, M; De Glisezinski, I; Galitzky, J; Lafontan, M; Sengenès, C | 1 |
| Dissing, S; Looms, DK; Nauntofte, B; Tritsaris, K | 1 |
| Araki, M; Fujita, M; Hasegawa, K; Iwai-Kanai, E; Kakita, T; Morimoto, T; Sasayama, S; Sawamura, T; Wada, H | 1 |
| Joyner, RW; Kumar, R; Wagner, MB; Wang, Y | 1 |
| Bozzi, A; Carnicelli, V; Delle Fave, G; Di Giulio, A; Oratore, A; Romano, G; Severi, C; Strom, R | 1 |
| Drexler, H; Klein, G; Schröder, F | 1 |
| Amirmansour, C; Harding, SE; Sarkar, D; Vallance, P | 1 |
| Lee, SS; Liu, H; Song, D | 1 |
| Eckhart, A; Gaballa, MA; Goldman, S; Koch, WJ | 1 |
| Ruskoaho, H; Tavi, P; Weckström, M | 1 |
| Kakiailatu, FA | 1 |
| Gupta, BB; Rimoldi, S; Spessert, R; Vollrath, L | 1 |
| Barnes, PJ; Belvisi, MG; Birrell, MA; Giembycz, MA; Hele, DJ; Spicuzza, L | 1 |
| Argibay, J; Hoebeke, J; Nascimento, JH; Peineau, N; Sallé, L | 1 |
| Jacobson, KL; Ott, SM; Singh, JC; Watson, EL | 1 |
| Leffler, CW; Willis, AP | 1 |
| Barry, WH; Ritter, M; Shelby, J; Su, Z; Xu, S; Yao, A; Zubair, I | 1 |
| Chik, CL; Ho, AK; Mackova, M; Price, L | 1 |
| Berlan, M; Galitzky, J; Hejnova, J; Lafontan, M; Pariskova, Z; Sengenes, C; Stich, V | 1 |
| Makhlouf, GM; Murthy, KS; Zhou, H | 1 |
| Tsuchida, K; Watajima, H | 1 |
| Andreasen, D; Friis, UG; Hansen, PB; Jensen, BL; Sethi, S; Skøtt, O | 1 |
| Berlan, M; Bouloumié, A; Galitzky, J; Lafontan, M; Moulin, A; Sengenès, C; Zakaroff-Girard, A | 1 |
| Brunton, LL; Gustafsson, AB | 1 |
| Furuyama, S; Michikawa, H; Sakai, T; Sugiya, H | 1 |
| Bertel, O; Brunner-La Rocca, HP; Kiowski, W; Oechslin, E; Schad, K; Schalcher, C; Scharf, C; Schindler, R; Suetsch, G | 1 |
| Baskakov, MB; D'yakova, EY; Kapilevich, LV; Kovalev, IV; Nosarev, AV | 1 |
| Deschepper, CF; Fortin, N; Picard, S; Reudelhuber, TL; Zahabi, A | 1 |
| Ames, S; Bastein, M; Drexler, H; Fiedler, B; Gambaryan, S; Hillmer, A; Klein, G; Lohmann, SM; Schnasse, N; Schröder, F; Walter, U; Wollert, KC | 1 |
| Berlan, M; Crampes, F; De Glisezinski, I; Galitzky, J; Lafontan, M; Moro, C; Sengenes, C; Thalamas, C | 1 |
| Bi, H; Guo, HT; Lu, SY; Pei, JM; Yu, J; Zhang, B; Zhang, HF; Zhang, RH; Zhu, MZ | 1 |
| Boujaoude, M; Missen, MA; Woodman, OL | 1 |
| Aufiero, K; Belardi, D; Champion, HC; Dostmann, WR; Isoda, T; Kass, DA; Mergia, E; Mongillo, M; Montrose, DC; Moslehi, J; Smith, CJ; Takimoto, E; Zaccolo, M | 1 |
| Keung, W; Man, RY; Vanhoutte, PM | 1 |
| Engel, L; Gerhold, S; Gupta, BB; Heinrich, B; Holthues, H; Lorenzkowski, V; Schwerdtle, I; Spessert, R; Vollrath, L | 1 |
| Hirst, GD; Ito, Y; Teramoto, N; Zhu, HL | 1 |
| Krylatov, AV; Lasukova, OV; Maslov, LN; Pertwee, R; Uzhachenko, RV | 1 |
| Batts, TW; Murphy, RA; Rembold, CM; Walker, JS | 1 |
| Rodriguez, R; Scholz, PM; Weiss, HR; Zhang, S | 1 |
| Cheung, YF; Dostmann, WR; Houslay, MD; Kass, DA; Lissandron, V; Mongillo, M; Paolocci, N; Pozzan, T; Terrin, A; Tocchetti, CG; Zaccolo, M | 1 |
| Davidov, T; Lazar, MJ; Moalem, J; Molino, B; Rodriguez, R; Scholz, PM; Weiss, HR | 1 |
| Adamo, C; Angelone, T; Cerra, MC; Imbrogno, S; Pulerà, E; Tota, B | 1 |
| Smith, JM; Sondgeroth, KB; Wahler, GM | 1 |
| Gupte, SA; Rabbani, G; Sarabu, MR; Vijay, V | 1 |
| Elgin, E; Haigney, MC; Hanlon, SU; McCurley, JM; Ruknudin, AM; Schulze, DH; Shou, M; Wei, SK | 1 |
| Belardi, D; Champion, HC; Cormaci, G; Kass, DA; Ketner, EA; Moens, AL; Takimoto, E; Tocchetti, CG; Vahebi, S | 1 |
| Kaneko, K; Tsuchida, K | 1 |
| Atagi, S; Isobe-Oku, S; Iwatani, Y; Kawasaki, H; Kitamura, Y; Kosugi, K | 1 |
| Akaike, A; Ito, R; Izumi, Y; Katsuki, H; Kume, T; Niidome, T; Sugimoto, H; Taguchi, R; Takada-Takatori, Y | 1 |
| Kohr, MJ; Traynham, CJ; Wang, H; Ziolo, MT | 1 |
| Barnucz, E; Hirschberg, K; Karck, M; Korkmaz, S; Loganathan, S; Neugebauer, P; Páli, S; Radovits, T; Seidel, B; Szabó, G; Veres, G; Zöllner, S | 1 |
| Abe, J; Beavo, JA; Blaxall, BC; Cai, Y; Chen, YF; Florio, V; Li, JD; Miller, CL; Nagel, DJ; Oikawa, M; Rybalkin, SD; Wojtovich, AP; Xu, H; Xu, X; Yan, C | 1 |
| Takimoto, E | 1 |
| Chen, IJ; Dai, ZK; Hsu, JH; Liou, SF; Liu, CP; Wu, BN; Wu, JR; Wu, PJ; Yeh, JL | 1 |
| Gao, S; Gul, R; Kim, SH; Kim, UH; Oh, YB; Shah, A; Yuan, K | 1 |
| Garthwaite, J; Wilson, GW | 1 |
| Angelone, T; Gattuso, A; Mazza, R; Pasqua, T | 1 |
| Adderley, SP; Bowles, EA; Ellsworth, ML; Sprague, RS; Sridharan, M; Stephenson, AH; Thuet, KM | 1 |
| D'Ocon, P; Estrada, S; Flacco, N; Ivorra, MD; Jiménez-Altayó, F; Noguera, MA; Perez-Aso, M; Segura, V; Seller, JF; Vila, E | 1 |
| Feng, Y; Hu, J; Lin, S; Lv, Q; Wu, G; Yang, J; Yang, Q | 1 |
| Aronsen, JM; Christensen, G; Hougen, K; Levy, FO; Meier, S; Moltzau, LR; Nguyen, CH; Osnes, JB; Qvigstad, E; Sjaastad, I; Skomedal, T; Ørstavik, Ø | 1 |
| Balligand, JL; Beauloye, C; Belge, C; Bertrand, L; Dessy, C; Dubois-Deruy, E; Esfahani, H; Götz, KR; Hamelet, J; Hammond, J; Herijgers, P; Hilfiker-Kleiner, D; Iaccarino, G; Jnaoui, K; Langin, D; Lobysheva, I; Manoury, B; Markl, A; Nikolaev, VO; Pouleur, AC; Tavernier, G; Vanderper, A | 1 |
| Anoopkumar-Dukie, S; Grant, GD; Hempenstall, A; Johnson, PJ | 1 |
| Davel, AP; Delbin, MA; Fukuda, LE; Rossoni, LV; Victorio, JA | 1 |
| Abesser, M; El-Armouche, A; Hübscher, D; Lehnart, SE; Nikolaev, VO; Perera, RK; Schuh, K; Sprenger, JU; Steinbrecher, JH | 1 |
| Alexandre, EC; Alves Junior, MJ; Antunes, E; Báu, FR; Calmasini, FB; Leiria, LO; Mónica, FZ; Silva, FH | 1 |
| Kuhn, M | 1 |
| Busch, M; Busch, R; Dörr, M; Eckerle, LG; Felix, SB; Gross, S; Hertrich, I; Rauch, BH; Reinke, Y; Riad, A; Stasch, JP | 1 |
| Li, D; Li, G; Tang, B; Wang, Q; Yang, D; Yang, Y; Zhang, Y | 1 |
| Manivasagam, S; Vellaichamy, E | 1 |
| Chang, P; Chen, W; Wang, J; Wang, X; Yu, J; Zhang, J; Zhang, X; Zhu, X | 1 |
| Cachorro, E; Dobrev, D; Dybkova, N; El-Armouche, A; Firneburg, R; Heijman, J; Kämmerer, S; Klapproth, E; Klehr, J; Kuenzel, SR; Lorenz, K; Mason, FE; Richter, K; Sadek, MS; Sossalla, S; Wagner, M | 1 |
| Agis-Torres, Á; Benedito, S; Climent, B; Fernandes, VS; Hernández, M; Hernández-Martín, M; López-Oliva, ME; Navarro-Dorado, J; Pilar Martínez, M; Recio, P; Victoria Barahona, M | 1 |
| Ahn, SH; Bae, SI; Chung, S; Hwang, Y; Lee, S; Ok, SH; Park, KE; Sim, G; Sohn, JT | 1 |
7 review(s) available for isoproterenol and cyclic gmp
| Article | Year |
|---|---|
Catecholamines and renal water excretion.
Topics: Animals; Blood Pressure; Cyclic AMP; Cyclic GMP; Dogs; Humans; Isoproterenol; Kidney; Norepinephrine; Parasympathetic Nervous System; Pituitary Gland; Vasopressins; Water | 1975 |
Role of cyclic nucleotides in the induction of tyrosine hydroxylase.
Topics: Adenylyl Cyclases; Adrenal Medulla; Animals; Atropine; Carbachol; Cold Temperature; Cyclic AMP; Cyclic GMP; Dexamethasone; Dopamine; Enzyme Induction; Ganglia; Glucocorticoids; Guanylate Cyclase; Hexamethonium Compounds; Isoproterenol; Organ Specificity; Phenoxybenzamine; Rats; Receptors, Adrenergic; Reserpine; Tyrosine 3-Monooxygenase | 1975 |
Synthesis and degradation of cyclic 3',5'-adenosine monophosphate in frog erythrocytes.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Anura; Cyclic AMP; Cyclic GMP; Epinephrine; Erythrocytes; Fluorides; Isoproterenol; Norepinephrine; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Propranolol; Stimulation, Chemical; Structure-Activity Relationship; Tritium | 1970 |
Effects of adrenergic nervous system and catecholamines on systemic and renal hemodynamics, sodium and water excretion and renin secretion.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Body Water; Catecholamines; Cyclic AMP; Cyclic GMP; Diuresis; Dogs; Glomerular Filtration Rate; Hemodynamics; Humans; Isoproterenol; Kidney; Norepinephrine; Osmolar Concentration; Rats; Receptors, Adrenergic; Renin; Sodium; Sympathetic Nervous System; Vasopressins | 1974 |
Selective interactions of cyclooxygenase and lipoxygenase metabolites with the cyclic GMP systems in the myometrium.
Topics: Animals; Arachidonic Acids; Calcimycin; Carbachol; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Female; Guanylate Cyclase; Guinea Pigs; Isoproterenol; Lipoxygenase; Lipoxygenase Inhibitors; Microtubules; Myometrium; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred Strains | 1984 |
Mechanisms involved in alpha-adrenergic phenomena: role of calcium ions in actions of catecholamines in liver and other tissues.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Epinephrine; Humans; Isoproterenol; Liver; Norepinephrine; Phenylephrine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1980 |
Cyclic nucleotides in immunosuppression--neuroendocrine pharmacologic manipulation and in vivo immunoregulation of immunity acting via second messenger systems.
Topics: Animals; Cyclic AMP; Cyclic GMP; Cytotoxicity, Immunologic; Immune Tolerance; Immunity, Cellular; Isoproterenol; Lymphocyte Activation; Mice; Rats; Receptors, Cell Surface; T-Lymphocytes; Theophylline | 1980 |
3 trial(s) available for isoproterenol and cyclic gmp
| Article | Year |
|---|---|
Hormone effects upon cyclic nucleotide excretion in man.
Topics: Adrenocorticotropic Hormone; Adult; Aminophylline; Clinical Trials as Topic; Cyclic AMP; Cyclic GMP; Epinephrine; Glucagon; Hormones; Humans; Hydrocortisone; Isoproterenol; Male; Parathyroid Hormone; Phentolamine; Physical Exertion; Propranolol; Radioimmunoassay; Stimulation, Chemical; Triiodothyronine; Tritium; Vasopressins | 1972 |
Interaction of sildenafil with cAMP-mediated vasodilation in vivo.
Topics: Adrenergic beta-Agonists; Adult; Blood Pressure; Brachial Artery; Cyclic AMP; Cyclic GMP; Forearm; Heart Rate; Hemodynamics; Humans; Isoproterenol; Male; Milrinone; Nitroglycerin; Phosphodiesterase Inhibitors; Piperazines; Purines; Regional Blood Flow; Sildenafil Citrate; Sulfones; Vasodilation; Vasodilator Agents | 2002 |
Atrial natriuretic peptide contributes to physiological control of lipid mobilization in humans.
Topics: Adipocytes; Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Atrial Natriuretic Factor; Blood Glucose; Cross-Over Studies; Cyclic GMP; Double-Blind Method; Epinephrine; Exercise; Exercise Test; Extracellular Fluid; Fatty Acids, Nonesterified; Glycerol; Guanylate Cyclase; Humans; Isoproterenol; Lipolysis; Male; Microdialysis; Norepinephrine; Oxygen Consumption; Phentolamine; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Receptors, Atrial Natriuretic Factor; Subcutaneous Tissue; Sympathetic Nervous System; Thiophenes | 2004 |
461 other study(ies) available for isoproterenol and cyclic gmp
| Article | Year |
|---|---|
Involvement of cyclic nucleotides in the beating response of rat heart cells in culture.
Topics: Acetylcholine; Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Glucagon; Hydrocortisone; Isoproterenol; Myocardial Contraction; Myocardium; Rats; Theophylline | 1976 |
Catecholamine-stimulated cyclic GMP accumulation in the rat pineal: apparent presynaptic site of action.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Isoproterenol; Kinetics; Male; Melatonin; Norepinephrine; Ouabain; Pineal Gland; Potassium; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sotalol; Stereoisomerism; Synaptic Membranes | 1976 |
A review of recent advances in vascular smooth muscle pharmacology.
Topics: Adenylyl Cyclases; Animals; Blood Vessels; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Ischemic Attack, Transient; Isoproterenol; Muscle, Smooth; Nitroprusside; Phosphodiesterase Inhibitors | 1977 |
Evidence for control of complement receptor rosette-forming cells by alpha and beta-adrenergic agents.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aminophylline; Animals; B-Lymphocytes; Binding Sites; Bucladesine; Complement System Proteins; Cyclic GMP; Epinephrine; Immune Adherence Reaction; Isoproterenol; Male; Mice; Mice, Inbred CBA; Norepinephrine; Phentolamine; Propranolol; Spleen | 1977 |
Adenosine 3':5'-monophosphate and guanosine 3':5'-monophosphate: levels and cyclase activities in liver and adipose tissue from diabetic mice (db/db).
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cyclic AMP; Cyclic GMP; Diabetes Mellitus; Disease Models, Animal; Guanylate Cyclase; Heterozygote; Homozygote; Isoproterenol; Liver; Male; Mice | 1978 |
Amylase secretion from the rat parotid: refractoriness to muscarinic and adrenergic agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; alpha-Amylases; Amylases; Animals; Carbachol; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Parasympathomimetics; Parotid Gland; Rats; Sympathomimetics | 1978 |
Adrenergic- and cyclic nucleotide-induced glycerol release from brown adipocytes.
Topics: Adenosine Monophosphate; Adipose Tissue, Brown; Adrenergic beta-Agonists; Animals; Cricetinae; Cyclic AMP; Cyclic GMP; Glycerol; Isoproterenol; Male; Mesocricetus; Phenylephrine; Theophylline | 1979 |
Effects of adrenergic drugs on aqueous cAMP and cGMP and intraocular pressure.
Topics: Administration, Topical; Adrenergic Agonists; Animals; Aqueous Humor; Cyclic AMP; Cyclic GMP; Epinephrine; Intraocular Pressure; Isoproterenol; Male; Phenylephrine; Rabbits; Terbutaline | 1979 |
Drug therapy: Bronchodilator therapy (first of two parts).
Topics: Adrenergic beta-Agonists; Adult; Bronchi; Bronchial Spasm; Bronchodilator Agents; Cyclic AMP; Cyclic GMP; Ephedrine; Epinephrine; Histamine Release; Humans; Isoproterenol; Mast Cells; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Respiratory Hypersensitivity; SRS-A; Sympathomimetics | 1977 |
Role of cyclic AMP in the regulation of renin release from the isolated perfused rat kidney.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Glomerular Filtration Rate; Isoproterenol; Kidney; Male; Rats; Renin; Sodium | 1978 |
Changes in histamine and cyclic nucleotide levels after bronchoprovocation in patients with extrinsic asthma.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Allergens; Asthma; Bronchial Spasm; Cyclic AMP; Cyclic GMP; Female; Histamine; Histamine Release; Humans; Isoproterenol; Leukocytes; Male; Middle Aged; Peak Expiratory Flow Rate; Phosphodiesterase Inhibitors; Receptors, Adrenergic, beta | 1978 |
Methacholine-induced attenuation of methylisobutylxanthine- and isoproterenol-elevated cyclic AMP levels in isolated rat atria.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic GMP; Electric Stimulation; Female; In Vitro Techniques; Isoproterenol; Methacholine Compounds; Myocardium; Rats; Theophylline | 1979 |
Ethanol inhibition of antigen-induced histamine release from guinea pig lung: correlation with intracellular levels of cyclic nucleotides.
Topics: Animals; Antigens; Cyclic AMP; Cyclic GMP; Ethanol; Guinea Pigs; Histamine Release; In Vitro Techniques; Isoproterenol; Lung; Male; Metiamide; Ovalbumin; Pyrilamine; Time Factors | 1979 |
Effect of synthetic cyclic nucleotides on immunologic histamine release from calf granulocytes.
Topics: Animals; Cattle; Cyclic AMP; Cyclic GMP; Granulocytes; Histamine; Histamine Release; Isoproterenol; Male; Receptors, Adrenergic, beta | 1979 |
The modulation of spontaneous and anti-Ig-stimulated motility of lymphocytes by cyclic nucleotides and adrenergic and cholinergic agents.
Topics: Acetylcholine; Animals; Antibodies, Anti-Idiotypic; Antigen-Antibody Complex; Atropine; B-Lymphocytes; Binding Sites; Carbachol; Cell Membrane; Cell Movement; Colchicine; Cyclic AMP; Cyclic GMP; Endocytosis; Immunoglobulins; Isoproterenol; Mice; Nucleotides, Cyclic; Parasympathomimetics; Phenylephrine; Sympathomimetics; Theophylline | 1975 |
Beta-adrenergic inhibition of human T lymphocyte rosettes.
Topics: Binding Sites, Antibody; Cell Membrane; Cell Survival; Cyclic AMP; Cyclic GMP; Humans; Immune Adherence Reaction; Immunity, Cellular; Isoproterenol; Propranolol; T-Lymphocytes | 1975 |
Cyclic nucleotides and gluconeogenesis by rat liver cells.
Topics: Animals; Carbachol; Catecholamines; Cyclic AMP; Cyclic GMP; Depression, Chemical; Dihydroergotamine; Epinephrine; Glucagon; Gluconeogenesis; In Vitro Techniques; Isoproterenol; Lactates; Liver; Liver Glycogen; Phenformin; Propranolol; Pyruvates; Rats; Tetracaine | 1975 |
The role of calcium and cyclic nucleotides in alpha-amylase release from slices of rat parotid: studies with the divalent cation ionophore A-23187.
Topics: Amylases; Animals; Atropine; Biological Transport; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; Isoproterenol; Parotid Gland; Phentolamine; Potassium; Propranolol; Rats; Stimulation, Chemical; Theophylline; Time Factors | 1975 |
Modulation of human neutrophil chemotactic responses by cyclic 3',5'-guanosine monophosphate and cyclic 3',5'-adenosine monophosphate.
Topics: Acetylcholine; Adult; Atropine; Carbachol; Chemotaxis; Cyclic AMP; Cyclic GMP; Depression, Chemical; Drug Interactions; Epinephrine; Histamine; Humans; Imidazoles; Isoproterenol; Neutrophils; Norepinephrine; Phenylephrine; Prostaglandins; Stimulation, Chemical | 1975 |
Cyclic nucleotides and the contraction of smooth muscle.
Topics: Animals; Atropine; Calcium; Carbachol; Cattle; Colon; Cyclic AMP; Cyclic GMP; Diethylstilbestrol; Guinea Pigs; Histamine; Isoproterenol; Microsomes; Mitochondria, Muscle; Muscle Contraction; Muscle, Smooth; Organ Specificity; Potassium; Prostaglandins; Rabbits; Rats | 1975 |
Cyclic nucleotides, protein phosphorylation, and neuronal function.
Topics: Animals; Anura; Caudate Nucleus; Cyclic AMP; Cyclic GMP; Dopamine; Erythrocytes; Isoproterenol; Kinetics; Models, Biological; Neurons; Phosphoproteins; Protein Kinases; Synaptic Membranes; Turkeys; Urinary Bladder; Vasopressins | 1975 |
Effects of pharmacologic agents on release of lysosomal enzymes from alveolar mononuclear cells.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Bucladesine; Colchicine; Cyclic AMP; Cyclic GMP; Cytochalasin B; Dimethyl Sulfoxide; Guinea Pigs; In Vitro Techniques; Isoproterenol; Leukocytes; Lysosomes; Macrophages; Microtubules; Prostaglandins E; Prostaglandins F; Pulmonary Alveoli; Theophylline | 1975 |
The action of neurotransmitter hormones and analogues and cyclic nucleotides and theophylline on electrolyte transport by the excretory duct of the rabbit mandibular gland.
Topics: Acetylcholine; Animals; Atropine; Biological Transport; Cell Membrane Permeability; Cyclic AMP; Cyclic GMP; Electrolytes; Female; Isoproterenol; Male; Norepinephrine; Rabbits; Salivary Glands; Theophylline | 1975 |
Interaction between cyclic adenosine monophosphate and cyclic gunaosine monophosphate in guinea pig ventricular myocardium.
Topics: Acetylcholine; Animals; Cyclic AMP; Cyclic GMP; Depression, Chemical; Drug Interactions; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Ouabain; Stimulation, Chemical | 1975 |
Manipulation of the cell cycle of the hemopoietic stem cell.
Topics: Acetylcholine; Anesthetics; Animals; Bucladesine; Carbachol; Cell Division; Cells, Cultured; Cyclic GMP; DNA; Endotoxins; Hematopoietic Stem Cells; In Vitro Techniques; Isoproterenol; Mice; Neostigmine; Parathyroid Hormone; Prostaglandins E; Receptors, Adrenergic; Receptors, Cholinergic; Testosterone | 1975 |
The effect of agents which modulate levels of the cyclic nucleotides on human lymphotoxin secretion and activity in vitro.
Topics: Bucladesine; Carbachol; Concanavalin A; Cyclic AMP; Cyclic GMP; Cytotoxicity Tests, Immunologic; Humans; Imidazoles; Isoproterenol; Lymphocytes; Lymphotoxin-alpha; Theophylline | 1975 |
Amylase secretion by rabbit parotid gland. Role of cyclic AMP and cyclic GMP.
Topics: Amylases; Animals; Atropine; Carbachol; Cyclic AMP; Cyclic GMP; Epinephrine; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Parotid Gland; Phenoxybenzamine; Propranolol; Rabbits | 1975 |
Comparison of the secretory processes in the parotid and sublingual glands of the mouse. 1. Regulation of the secretory processes.
Topics: Acetylcholine; Amylases; Animals; Bucladesine; Calcium; Cyclic AMP; Cyclic GMP; Epinephrine; Female; Isoproterenol; Mice; Norepinephrine; Parotid Gland; Pilocarpine; Proteins; Sialic Acids; Sublingual Gland | 1975 |
Drug-induced alterations in morphology and level of cAMP in cultured human glioma cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Catecholamines; Cell Line; Cyclic AMP; Cyclic GMP; Dimethyl Sulfoxide; Epinephrine; Glioma; Isoproterenol; Neurons; Papaverine; Phenoxybenzamine; Prostaglandins E; Sotalol; Zeatin | 1975 |
Calcium ion uptake in isolated pancreas cells induced by secretagogues.
Topics: Animals; Biological Transport, Active; Bucladesine; Calcimycin; Calcium; Carbachol; Ceruletide; Cholecystokinin; Cyclic GMP; Epinephrine; Gastrins; Gastrointestinal Agents; In Vitro Techniques; Isoproterenol; Kinetics; Mathematics; Pancreas; Rats; Secretin; Sympathomimetics | 1976 |
Opposing regulatory influences of cyclic guanosine monophosphate and cyclic adenosine monophosphate in the control of cardiac muscle contraction.
Topics: Acetylcholine; Animals; Atropine; Cyclic AMP; Cyclic GMP; Heart Atria; Isoproterenol; Myocardial Contraction; Rabbits | 1975 |
Regulation by insulin of gluconeogenesis in isolated rat hepatocytes.
Topics: Acetates; Alanine; Animals; Cyclic AMP; Cyclic GMP; Epinephrine; Glucagon; Gluconeogenesis; In Vitro Techniques; Insulin; Isoproterenol; Kinetics; Lactates; Liver; Rats | 1976 |
Neuroblastoma cell adenylate cyclase: direct activation by adenosine and prostaglandins.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenylyl Cyclases; Cell Line; Cyclic GMP; Dopamine; Isoproterenol; Kinetics; Neoplasms, Experimental; Neuroblastoma; Norepinephrine; Papaverine; Prostaglandins E; Prostaglandins F; Theophylline | 1976 |
Decreased vascular relaxation in hypertension.
Topics: Adenosine; Animals; Aorta, Thoracic; Bucladesine; Cyclic GMP; Female; Hypertension, Renal; Isoproterenol; Male; Muscle Contraction; Nitroglycerin; Rats; Rats, Inbred Strains; Serotonin; Vasomotor System | 1976 |
Relationship between the levels of intracellular cyclic nucleotides and mechanical responses induced by drugs.
Topics: Acetylcholine; Animals; Cyclic AMP; Cyclic GMP; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Time Factors; Trachea | 1976 |
Effect of isoproterenol and acetylcholine treatment in vitro on cyclic nucleotides in mouse sex accessory organs.
Topics: Acetylcholine; Animals; Atropine; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Prostate; Rats; Seminal Vesicles; Testis | 1976 |
Studies on the role of cyclic guanosine 3':5'-monophosphate and extracellular Ca2+ in the regulation of glycogenolysis in rat liver cells.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Atropine; Calcimycin; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Dihydroergotamine; Epinephrine; Female; Glucagon; Glucose; In Vitro Techniques; Insulin; Isoproterenol; Liver; Liver Glycogen; Phenoxybenzamine; Propranolol; Rats | 1976 |
Oppositional effects of acetylcholine and isoproterenol on isometric tension and cyclic nucleotide concentrations in rabbit atria.
Topics: Acetylcholine; Animals; Atrial Function; Atropine; Cyclic AMP; Cyclic GMP; Heart Atria; Isoproterenol; Myocardial Contraction; Myocardium; Rabbits | 1975 |
Catecholamine antagonism of acetylcholine and dibutyrl guanosine 3',-5'-monophosphate in the mammalian ventricular myocardium.
Topics: Acetylcholine; Animals; Atropine; Cats; Cyclic GMP; Depression, Chemical; Dose-Response Relationship, Drug; Glycolysis; Heart Rate; Heart Ventricles; Hydroxydopamines; Isoproterenol; Kinetics; Models, Biological; Myocardium; Reserpine; Tetrodotoxin; Ventricular Function | 1975 |
Regulation of bacterial motility by cyclic nucleotides and effect of biogenic amines.
Topics: Adenosine; Biogenic Amines; Bucladesine; Cell Movement; Chlorpromazine; Cyclic AMP; Cyclic GMP; Dopamine; Escherichia coli; Histamine; Isoproterenol; Kinetics; Papaverine; Reserpine; Ribonucleotides; Spermine | 1976 |
The regulation of kallikrein secretion from isolated submandibular gland slices by neurotransmitters, cyclic nucleotides and calcium.
Topics: Acetylcholine; Animals; Atropine; Calcium; Cyclic AMP; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kallikreins; Norepinephrine; Nucleotides, Cyclic; Phentolamine; Phenylephrine; Propranolol; Submandibular Gland | 1976 |
Modulation of human T lymphocyte rosette formation by autonomic agonists and cyclic nucleotides.
Topics: Atropine; Carbachol; Cyclic AMP; Cyclic GMP; Histamine; Humans; Immune Adherence Reaction; Isoproterenol; Phentolamine; Phenylephrine; Propranolol; T-Lymphocytes | 1976 |
Hormone-stimulated glycogenolysis in isolated goldfish hepatocytes.
Topics: Adenosine Triphosphate; Animals; Cyclic AMP; Cyclic GMP; Cyprinidae; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Glucose; Goldfish; In Vitro Techniques; Isoproterenol; Liver; Liver Glycogen | 1976 |
Biochemical aspects of cardiac muscle differentiation. Possible control of deoxyribonucleic acid synthesis and cell differentiation by adrenergic innervation and cyclic adenosine 3':5'-monophosphate.
Topics: Aging; Animals; Animals, Newborn; Bucladesine; Cell Differentiation; Cyclic AMP; Cyclic GMP; DNA Replication; Heart; Isoproterenol; Muscle Proteins; Muscle, Smooth; Myocardium; Myosins; Norepinephrine; Phenylephrine; Protein Biosynthesis; Rats; Theophylline | 1976 |
Calcium-dependent regulation of guanosine 3',5'-monophosphate in renal cortex: effects of ionophore A23187 and tetracaine and evidence for independent control of adenosine 3',5'-monophosphate.
Topics: Animals; Anti-Bacterial Agents; Atropine; Calcimycin; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Glucagon; In Vitro Techniques; Isoproterenol; Kidney Cortex; Kinetics; Magnesium; Male; Parathyroid Hormone; Rats; Tetracaine; Theophylline | 1976 |
Mechanism of inhibition of organic acid transport in rabbit renal cortex by cyclic AMP.
Topics: Adenine; Animals; Biological Transport, Active; Cyclic AMP; Cyclic GMP; Iodohippuric Acid; Isoproterenol; Kidney Cortex; Kinetics; Parathyroid Hormone; Propranolol; Rabbits; Theophylline; Uric Acid | 1976 |
Phosphorylation in vitro of proteins in the pancreas and parotids of rats: effects of hormonal secretagogues and cyclic nucleotides.
Topics: Amylases; Animals; Bucladesine; Carbachol; Ceruletide; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Nucleotides, Cyclic; Pancreas; Parotid Gland; Proteins; Rats; Secretin | 1975 |
Stimulus-secretion coupling: role of cyclic AMP, cyclic GMP and calcium in mediating enzyme (kallikrein) secretion in the submandibular gland.
Topics: Acetylcholine; Animals; Atropine; Bucladesine; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kallikreins; Male; Norepinephrine; Phentolamine; Phenylephrine; Propranolol; Stimulation, Chemical; Submandibular Gland | 1976 |
Interconversion of myocardial adrenoceptors: its relationship to adenylate cyclase activation.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Cyclic GMP; Enzyme Activation; Isoproterenol; Male; Myocardial Contraction; Myocardium; Phenoxybenzamine; Phentolamine; Phenylephrine; Propranolol; Rats; Receptors, Adrenergic; Thyroid Gland | 1976 |
Non-histone-protein phosphorylation in rat salivary glands after treatment with isoproterenol, dibutyryladenosine cyclic monophosphate and dibutyrylguanosine cyclic monophosphate.
Topics: Animals; Bucladesine; Chromosomal Proteins, Non-Histone; Cyclic GMP; Isoproterenol; Phosphoproteins; Rats; Salivary Glands; Theophylline | 1976 |
Studies on the phosphorylation of the inhibitory subunit of troponin during modification of contraction in perfused rat heart.
Topics: Acetylcholine; Animals; Chromatography, Affinity; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Glucagon; In Vitro Techniques; Isoproterenol; Male; Muscle Proteins; Myocardial Contraction; Phosphates; Phosphorylases; Rats; Time Factors; Troponin | 1976 |
Role of cyclic nucleotides in human lymphocyte-mediated antibody-dependent cytotoxicity.
Topics: Acetylcholine; Antibodies; Bucladesine; Carbachol; Cyclic AMP; Cyclic GMP; Cytotoxicity Tests, Immunologic; Depression, Chemical; Drug Synergism; Histamine; Humans; Isoproterenol; Lymphocytes; Prostaglandins E; Theophylline | 1977 |
Agonist induced release of intracellular Ca2+ in the rabbit aorta.
Topics: Angiotensin II; Animals; Aorta; Biological Transport; Calcium; Cyclic GMP; Egtazic Acid; Histamine; Isoproterenol; Kinetics; Lanthanum; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Rabbits | 1977 |
Rosette formation by human T and B lymphocytes in the presence of adrenergic and cholinergic drugs.
Topics: Atropine; Autonomic Agents; B-Lymphocytes; Bucladesine; Butyrates; Carbachol; Cyclic AMP; Cyclic GMP; Humans; Immunologic Techniques; Isoproterenol; Lymphocytes; Papaverine; Pilocarpine; Propranolol; T-Lymphocytes; Theophylline | 1976 |
Dissociation of increases in levels of 3':5'-cyclic AMP and 3':5'-cyclic GMP from induction of ornithine decarboxylase by the tumor promoter 12-O-tetradecanoyl phorbol-13-acetate in mouse epidermis in vivo.
Topics: Animals; Carboxy-Lyases; Cyclic AMP; Cyclic GMP; Enzyme Induction; Female; Isoproterenol; Kinetics; Mice; Ornithine Decarboxylase; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1977 |
(3H)-isoproterenol binding to subcellular fractions of mouse parotid: relationship to cyclic nucleotide formation and the stimulation of DNA synthesis.
Topics: Adenosine Monophosphate; Animals; Binding Sites; Cell Membrane; Cyclic GMP; DNA; Isoproterenol; Kidney; Liver; Lung; Mice; Myocardium; Parotid Gland; Stimulation, Chemical; Tritium | 1976 |
Rat osteogenic sarcoma cells: isolation and effects of hormones on the production of cyclic AMP and cyclic GMP.
Topics: Adrenocorticotropic Hormone; Animals; Calcitonin; Cyclic AMP; Cyclic GMP; Glucagon; Glucose; Growth Hormone; Hormones; Insulin; Isoproterenol; Nucleotides, Cyclic; Osteosarcoma; Parathyroid Hormone; Prolactin; Prostaglandins; Rats; Theophylline; Thyroxine | 1977 |
Cyclic nucleotide changes in human neutrophils induced by chemoattractants and chemotactic modulators.
Topics: Carbachol; Chemotaxis, Leukocyte; Complement System Proteins; Cyclic AMP; Cyclic GMP; Dipeptides; Drug Synergism; Escherichia coli; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Neutrophils; Phenylephrine; Prostaglandins E; Prostaglandins F; Tetradecanoylphorbol Acetate | 1977 |
Rat gastric mucosal cAMP and cGMP after adrenergic stimulation and blockade.
Topics: Animals; Cyclic AMP; Cyclic GMP; Epinephrine; Female; Gastric Mucosa; Isoproterenol; Phenoxybenzamine; Phenylephrine; Propranolol; Rats; Sympathetic Nervous System; Time Factors | 1977 |
Human lung tissue and anaphylaxis. Evidence that cyclic nucleotides modulate the immunologic release of mediators through effects on microtubular assembly.
Topics: Anaphylaxis; Colchicine; Cold Temperature; Cyclic AMP; Cyclic GMP; Edetic Acid; Histamine Release; Humans; Isoproterenol; Lung; Microtubules; Nucleotides, Cyclic; SRS-A | 1977 |
Modulation of cyclic nucleotide levels in peripheral nerve without effect on resting or compound action potentials.
Topics: Action Potentials; Animals; Anura; Carbachol; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Rana pipiens; Sciatic Nerve; Theophylline | 1977 |
Alpha adrenergic involvement in heart metabolism: effects on adenosine cyclic 3',5'-monophosphate, adenosine cyclic 3',5'-monophosphate-dependent protein kinase, guanosine cyclic 3',5'-monophosphate, and glucose transport.
Topics: Animals; Biological Transport; Calcium; Cyclic AMP; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Glucose; In Vitro Techniques; Isoproterenol; Male; Myocardium; Phentolamine; Phenylephrine; Phosphodiesterase Inhibitors; Propranolol; Protein Kinases; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reserpine; Time Factors; Xanthines | 1977 |
["E" rosette formation in "active" T lymphocytes: phenomenon modulated by intracellular level of cyclic AMP and GMP (author's transl)].
Topics: Acetylcholine; Adenosine Triphosphate; Aminophylline; Animals; Carbachol; Cyclic AMP; Cyclic GMP; Dinitrophenols; Glucose; Isoproterenol; Levamisole; Phosphodiesterase Inhibitors; Rosette Formation; T-Lymphocytes | 1977 |
Modulation of human leucocyte migration inhibitory factor (LIF) by 3',5'-cyclic AMP, 3',5'-cyclic GMP and agents known to influence intracellular cyclic nucleotide metabolism.
Topics: Bucladesine; Cell Movement; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Dipyridamole; Humans; Isoproterenol; Leukocytes; Macrophage Migration-Inhibitory Factors; Norepinephrine; Nucleosides; Nucleotides, Cyclic; Papaverine; Phosphodiesterase Inhibitors | 1977 |
Role of cyclic nucleotides in the proliferation of committed granulocyte-macrophage progenitor cells.
Topics: Binding Sites; Bucladesine; Carbachol; Cell Division; Clone Cells; Colony-Stimulating Factors; Cyclic AMP; Cyclic GMP; Granulocytes; Hematopoiesis; Isoproterenol; Leukocytes; Macrophages; Prostaglandins; Prostaglandins E; Prostaglandins F | 1977 |
Refractoriness to muscarinic and adrenergic agonists in the rat parotid: responses of adenosine and guanosine cyclic 3', 5'-monophosphates.
Topics: Animals; Atropine; Azides; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Parasympathomimetics; Parotid Gland; Rats; Sympathomimetics; Time Factors | 1977 |
Lack of correlation between the positive inotropic effect evoked by alpha-adrenoceptor stimulation and the levels of cyclic AMP and/or cyclic GMP in the isolated ventricle strip of the rabbit.
Topics: Animals; Cyclic AMP; Cyclic GMP; Female; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Myocardium; Papaverine; Phentolamine; Phenylephrine; Pindolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stimulation, Chemical | 1978 |
A simple method for sampling murine pulmonary and cardiac tissues for analysis of cyclic nucleotide levels.
Topics: Animals; Cyclic AMP; Cyclic GMP; Energy Metabolism; Female; Freezing; Isoproterenol; Lung; Methods; Mice; Mice, Inbred ICR; Myocardium; Oxygen; Temperature; Time Factors | 1978 |
Effects of isoprenaline on contractile force and intracellular cyclic 3',5'-nucleotide levels in the hypodynamic frog ventricle.
Topics: Animals; Anura; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Heart Ventricles; Isoproterenol; Myocardial Contraction; Myocardium; Perfusion; Rana esculenta; Rana temporaria; Ventricular Function | 1978 |
The generation and regulation of lymphocyte populations: evidence from differentiative induction systems in vitro.
Topics: Animals; B-Lymphocytes; Cell Differentiation; Cell Separation; Cyclic AMP; Cyclic GMP; Endotoxins; Epinephrine; Imidazoles; Isoproterenol; Lymphocytes; Mice; Peptides; Poly A-U; Propranolol; Prostaglandins E; T-Lymphocytes; Theophylline; Thymopoietins | 1978 |
Alterations in activities of cyclic nucleotide systems and in beta-adrenergic receptor-mediated activation of cyclic AMP-dependent protein kinase during progression and regression of isoproterenol-induced cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Cyclic AMP; Cyclic GMP; Enzyme Activation; Isoproterenol; Male; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Protein Kinases; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1978 |
8-bromo-guanosine-3',5' -monophosphate mimics the effect of acetylcholine on slow response action potential and contractile force in mammalian atrial myocardium.
Topics: Acetylcholine; Action Potentials; Animals; Calcium; Cyclic GMP; Electric Conductivity; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction | 1978 |
Effect of cyclic nucleotides, isoproterenol and cholera toxin on DNA synthesis triggered by mitogens.
Topics: Animals; Cholera Toxin; Cyclic AMP; Cyclic GMP; DNA; Dose-Response Relationship, Immunologic; Isoproterenol; Lymphocyte Activation; Mitogens; Rabbits | 1978 |
Influences of cyclic nucleotides on outflow facility in the vervet monkey.
Topics: Animals; Aqueous Humor; Bucladesine; Chlorocebus aethiops; Cyclic AMP; Cyclic GMP; Epinephrine; Female; Haplorhini; In Vitro Techniques; Intraocular Pressure; Isoproterenol; Male; Sulfides; Time Factors | 1978 |
Effect of extracellular Na on isoproterenol-induced cAMP levels in depolarized uterus.
Topics: Animals; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; Gallopamil; In Vitro Techniques; Isoproterenol; Potassium; Rats; Sodium; Uterine Contraction; Uterus | 1978 |
Low concentrations of lithium inhibit the synthesis of cyclic AMP and cyclic GMP in the rat pineal gland.
Topics: Animals; Cyclic AMP; Cyclic GMP; Darkness; Fluorides; Isoproterenol; Kinetics; Light; Lithium; Magnesium; Male; Norepinephrine; Pineal Gland; Rats | 1979 |
Potentiation of guanosine 3':5'-monophosphate accumulation in C-6 glial tumor cells.
Topics: Adenylyl Cyclases; Astrocytes; Astrocytoma; Azides; Calcium; Cell Line; Cyclic AMP; Cyclic GMP; Isoproterenol; Neoplasms, Experimental; Norepinephrine; Receptors, Adrenergic, beta | 1979 |
Effects of papaverine and its interaction with isoprenaline and carbachol on the contractile force and cyclic nucleotide levels of the canine ventricular myocardium.
Topics: Animals; Carbachol; Cyclic AMP; Cyclic GMP; Dogs; Drug Interactions; Female; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Papaverine; Time Factors | 1979 |
The inhibitory effect of paraquat on histamine and isoproterenol induced changes of cyclic nucleotides in rat lung slices.
Topics: Animals; Cyclic AMP; Cyclic GMP; Histamine; In Vitro Techniques; Isoproterenol; Kinetics; Lung; Male; Paraquat; Rats | 1979 |
Cholinergic inhibition of catecholamine-stimulable cyclic AMP accumulation in murine atria.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Carbachol; Cholera Toxin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Heart; Isoproterenol; Male; Mice; Myocardium; Nitroprusside; Phosphodiesterase Inhibitors; Receptors, Muscarinic | 1979 |
Failure of dibutyryl and 8-bromo-cyclic GMP to mimic the antagonistic action of carbachol on the positive inotropic effects of sympathomimetic amines in the canine isolated ventricular myocardium.
Topics: Animals; Bucladesine; Carbachol; Cyclic GMP; Dibutyryl Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Female; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Norepinephrine; Phenylephrine; Stimulation, Chemical; Sympathomimetics | 1979 |
Metabolism of cyclic nucleotides in allergic rhinitis: studies on lymphocytes, granulocytes, and plasma level.
Topics: Adolescent; Adult; Asthma; Child; Cyclic AMP; Cyclic GMP; Granulocytes; Humans; Isoproterenol; Lymphocytes; Middle Aged; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Theophylline | 1979 |
Guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate content of human umbilical artery.
Topics: Acetylcholine; Atropine; Bradykinin; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; Histamine; Histamine H1 Antagonists; Humans; Infant, Newborn; Isoproterenol; Potassium Chloride; Pregnancy; Prostaglandins; Serotonin; Time Factors; Tritium; Umbilical Arteries | 1975 |
Induction of tyrosine hydroxylase elicited by beta adrenergic receptor agonists in normal and decentralized sympathetic ganglia: role of cyclic 3',5' - adenosine monophosphate.
Topics: Adrenal Medulla; Adrenergic beta-Agonists; Animals; Carbachol; Corticosterone; Cyclic AMP; Cyclic GMP; Decerebrate State; Enzyme Induction; Epinephrine; Ganglia, Autonomic; Hexamethonium Compounds; Isoproterenol; Male; Norepinephrine; Propranolol; Rats; Stimulation, Chemical; Tyrosine 3-Monooxygenase | 1975 |
Synergistic action of cyclic GMP on catecholamine-induced chloride current in guinea-pig ventricular cells.
Topics: Animals; Catecholamines; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Heart Ventricles; Histamine; Ion Channels; Isoproterenol; Membrane Potentials; Milrinone; Myocardium; Pyridones | 1992 |
Direct evidence for cross-activation of cGMP-dependent protein kinase by cAMP in pig coronary arteries.
Topics: Animals; Arteries; Atrial Natriuretic Factor; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Enzyme Activation; In Vitro Techniques; Isoproterenol; Nitroprusside; Protein Kinases; Second Messenger Systems; Swine | 1992 |
Impaired vasodilatory response to atrial natriuretic peptide during atherosclerosis progression.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arteriosclerosis; Atrial Natriuretic Factor; Cholesterol; Cyclic GMP; Endothelium, Vascular; Female; Hyperlipidemias; Isoproterenol; Male; Nitroglycerin; Rabbits; Triglycerides; Vasodilation | 1992 |
Hormonal activation of the cGMP-inhibited low-Km cyclic AMP phosphodiesterase of rat adipocytes from different sites: influence of ovariectomy.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Insulin; Isoproterenol; Ovariectomy; Ovary; Protein Kinases; Rats; Rats, Inbred Strains; Subcellular Fractions | 1992 |
Effects of CD-349 and 8-BrcGMP on isoproterenol-induced relaxation in rabbit aorta precontracted with endothelin-1.
Topics: Animals; Aorta; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Dihydropyridines; Drug Synergism; Endothelins; Isoproterenol; Male; Rabbits; Vasoconstriction; Vasodilation | 1992 |
Intracellular pH on protein kinase C and ionomycin potentiation of isoproterenol-stimulated cyclic AMP and cyclic GMP production in rat pinealocytes.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Cyclic AMP; Cyclic GMP; Hydrogen-Ion Concentration; Ionomycin; Isoproterenol; Male; Nifedipine; Phorbol Esters; Pineal Gland; Propionates; Protein Kinase C; Rats; Rats, Sprague-Dawley | 1992 |
Novel signal transduction pathway mediating endothelium-dependent beta-adrenoceptor vasorelaxation in rat thoracic aorta.
Topics: Albuterol; Animals; Aorta, Thoracic; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Nitroprusside; Norepinephrine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction | 1992 |
Regional difference in functional roles of cAMP and cGMP in lower urinary tract smooth muscle contractility.
Topics: Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Rabbits; Urethra; Urinary Bladder | 1992 |
NG-methyl-L-arginine decreases contractility, cGMP and cAMP in isoproterenol-stimulated rat hearts in vitro.
Topics: Animals; Arginine; Coronary Circulation; Cyclic AMP; Cyclic GMP; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1992 |
cAMP-dependent protein kinase activation mediated by beta 3-adrenergic receptors parallels lipolysis in rat adipocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Adrenergic beta-Agonists; Animals; Cyclic AMP; Cyclic GMP; Enzyme Activation; Ethanolamines; Isoproterenol; Lipolysis; Male; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1992 |
Adrenergic mechanisms associated with the movement of platelets in iridophores from the freshwater goby, Odontobutis obscura.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Platelets; Cell Movement; Cells, Cultured; Chromatophores; Colforsin; Cyclic GMP; Fishes; Isoproterenol; Norepinephrine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1992 |
Inhibition of nitrovasodilator- and acetylcholine-induced relaxation and cyclic GMP accumulation by the cytochrome P-450 substrate, 7-ethoxyresorufin.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Aorta; Biotransformation; Cyclic GMP; Cytochrome P-450 Enzyme System; Drug Interactions; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxazines; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1992 |
Hormone-sensitive cyclic GMP-inhibited cyclic AMP phosphodiesterase in rat adipocytes. Regulation of insulin- and cAMP-dependent activation by phosphorylation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Deaminase; Adipose Tissue; Animals; Cells, Cultured; Cyclic AMP; Cyclic GMP; Enzyme Activation; Insulin; Isoproterenol; Kinetics; Male; Phenylisopropyladenosine; Phosphorylation; Rats; Rats, Inbred Strains | 1991 |
Differential involvement of the arachidonic acid cascade on the alpha 1-adrenergic potentiation of vasoactive intestinal peptide- versus beta-adrenergic-stimulated cyclic AMP and cyclic GMP accumulation in rat pinealocytes.
Topics: Animals; Arachidonic Acids; Cells, Cultured; Cyclic AMP; Cyclic GMP; Indomethacin; Isoproterenol; Kinetics; Masoprocol; Phenylephrine; Pineal Gland; Prostaglandins; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasoactive Intestinal Peptide | 1991 |
Intracellular pH on adrenergic-stimulated cAMP and cGMP production in rat pinealocytes.
Topics: Ammonium Chloride; Animals; Calcium; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Extracellular Space; Hydrogen-Ion Concentration; Intracellular Membranes; Isoproterenol; Norepinephrine; Phosphodiesterase Inhibitors; Pineal Gland; Propionates; Rats; Sympathomimetics | 1991 |
Fluoride is a contractile agent of guinea pig airway smooth muscle.
Topics: Aluminum; Animals; Calcium; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Isoproterenol; Lung; Male; Muscle Contraction; Muscle, Smooth; Sodium Fluoride; Trachea | 1991 |
N omega-nitro-L-arginine methyl ester selectively inhibits pulmonary vasodilator responses to acetylcholine and bradykinin.
Topics: Acetylcholine; Alprostadil; Animals; Arginine; Bradykinin; Cats; Cyclic GMP; Female; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Pulmonary Circulation; Vasodilation | 1991 |
Modulation of agonist-induced calcium mobilisation in bovine aortic endothelial cells by phorbol myristate acetate and cyclic AMP but not cyclic GMP.
Topics: Animals; Aorta; Arginine; Bradykinin; Calcium; Calcium Channel Agonists; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Isoproterenol; Nitroarginine; Nitroprusside; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Functional antagonism in rabbit pulmonary veins contracted by endothelin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Endothelins; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Phenylephrine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Veins; Rabbits; Receptors, Cell Surface | 1991 |
GTP-related difference in cyclic AMP production between resident and inflammatory human peritoneal macrophages.
Topics: Adenylyl Cyclases; Cell Separation; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dinoprostone; Epoprostenol; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Isoproterenol; Macrophages; Peritoneal Cavity; Sodium Fluoride | 1991 |
Potentiation by cyclic GMP of beta-adrenergic effect on Ca2+ current in guinea-pig ventricular cells.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Dialysis; Drug Synergism; Guinea Pigs; Heart; Isoproterenol; Myocardium; Protein Kinases | 1991 |
Down-regulation of pinealocyte protein kinase C: effect on alpha 1-adrenergic potentiation of beta-adrenoceptor stimulation of cyclic AMP accumulation and induction of serotonin N-acetyltransferase activity.
Topics: Adrenergic alpha-Agonists; Animals; Arylamine N-Acetyltransferase; Cyclic AMP; Cyclic GMP; Down-Regulation; Enzyme Induction; Isoproterenol; Phenylephrine; Phorbol 12,13-Dibutyrate; Pineal Gland; Protein Kinase C; Rats; Rats, Inbred Strains | 1991 |
Relationship between cyclic guanosine monophosphate accumulation and relaxation of canine trachealis induced by nitrovasodilators.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic GMP; Dogs; Drug Synergism; Female; Guanylate Cyclase; Hemoglobins; Isoproterenol; Male; Methylene Blue; Muscle Relaxation; Nitroglycerin; Nitroprusside; Penicillamine; Purinones; S-Nitroso-N-Acetylpenicillamine; Time Factors; Trachea; Vasodilator Agents | 1991 |
Implication of cyclic AMP in the positive inotropic effects of cyclic GMP-inhibited cyclic AMP phosphodiesterase inhibitors on guinea pig isolated left atria.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Chloride; Cardiotonic Agents; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Milrinone; Myocardial Contraction; Myocardium; Protoveratrines; Pyrazines; Pyridones; Sodium | 1990 |
Effects of 8-bromo-cyclic GMP on contraction and on inotropic response of ferret cardiac muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Ferrets; Isoproterenol; Myocardial Contraction; Papillary Muscles | 1991 |
Interactions between isoprenaline, sodium nitroprusside, and isozyme-selective phosphodiesterase inhibitors on ADP-induced aggregation and cyclic nucleotide levels in human platelets.
Topics: Cyclic AMP; Cyclic GMP; Drug Interactions; Humans; Isoproterenol; Nitroprusside; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinones; Quinolones | 1991 |
Effects of 8-bromo-cyclic GMP on slow channel mediated action potentials of 3-days-old embryonic chick ventricle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Chick Embryo; Colforsin; Cyclic GMP; Heart Ventricles; Ion Channels; Isoproterenol; Ventricular Function | 1991 |
Rhythmic smooth muscle activity in hamster aortas is mediated by continuous release of NO from the endothelium.
Topics: Animals; Aorta; Cricetinae; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Isoproterenol; Male; Mesocricetus; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Phenylephrine; Vasoconstriction | 1991 |
N omega-nitro-L-arginine attenuates endothelium-dependent pulmonary vasodilation in lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine Triphosphate; Animals; Arginine; Binding, Competitive; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Hypertension, Pulmonary; Isoproterenol; Lung; Nitric Oxide; Nitroarginine; Nitroprusside; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Sheep; Vasodilation | 1991 |
Miniglucagon [glucagon-(19-29)] is a component of the positive inotropic effect of glucagon.
Topics: Animals; Atrial Natriuretic Factor; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic GMP; Glucagon; Heart; Heart Ventricles; Isoproterenol; Kinetics; Myocardial Contraction; Peptide Fragments; Ventricular Function | 1991 |
Nitroprusside enhances isoprenaline-induced increases in cAMP in rat aortic smooth muscle.
Topics: Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Rats; Rats, Inbred WKY | 1990 |
Beta-adrenergic regulation of cyclic GMP in rat pinealocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Cells, Cultured; Cyclic AMP; Cyclic GMP; Epinephrine; Isoproterenol; Kinetics; Norepinephrine; Pineal Gland; Prazosin; Rats; Rats, Inbred Strains; Terbutaline | 1990 |
Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Autoradiography; Cells, Cultured; Cyclic GMP; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Immunoblotting; Insulin; Isoproterenol; Kinetics; Male; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Rats; Rats, Inbred Strains | 1990 |
Immunocytology on microwave-fixed cells reveals rapid and agonist-specific changes in subcellular accumulation patterns for cAMP or cGMP.
Topics: Animals; Atrial Natriuretic Factor; Calcitonin; Cell Line; Cell-Free System; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Fibroblasts; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Humans; Immunoenzyme Techniques; Isoproterenol; Mice; Microwaves; Nitroprusside; Skin; Subcellular Fractions; Thiocyanates | 1990 |
Partial characterization of cyclic AMP-dependent protein kinases in guinea-pig lung employing the synthetic heptapeptide substrate, kemptide. In vitro sensitivity of the soluble enzyme to isoprenaline, forskolin, methacholine and leukotriene D4.
Topics: Adenosine Triphosphate; Animals; Carrier Proteins; Chromatography, DEAE-Cellulose; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Guinea Pigs; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoenzymes; Isoproterenol; Lung; Magnesium; Male; Methacholine Chloride; Methacholine Compounds; Oligopeptides; Protein Kinase Inhibitors; Protein Kinases; Solubility; SRS-A | 1990 |
Cumene hydroperoxide, an agent inducing lipid peroxidation, and 4-hydroxy-2,3-nonenal, a peroxidation product, cause coronary vasodilatation in perfused rat hearts by a cyclic nucleotide independent mechanism.
Topics: Aldehydes; Animals; Benzene Derivatives; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Lipid Peroxidation; Male; Myocardium; Rats; Rats, Inbred Strains; Vasodilation | 1990 |
Inhibitory effects of amilorides on pinealocyte adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate accumulation: possible involvement of postreceptor mechanisms.
Topics: Amiloride; Animals; Carrier Proteins; Cyclic AMP; Cyclic GMP; Drug Synergism; Hydrogen-Ion Concentration; Isoproterenol; Male; Norepinephrine; Phenylephrine; Pineal Gland; Potassium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1990 |
Pharmacological regulation of the circulation of bone.
Topics: Acetylcholine; Animals; Atropine; Bone and Bones; Bucladesine; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Isoproterenol; Methoxamine; Nitroglycerin; Peptides; Propanolamines; Prostaglandin Endoperoxides, Synthetic; Receptors, Drug; Regional Blood Flow; Tibia; Vasoconstrictor Agents; Vasodilator Agents | 1990 |
Superoxide anion inhibits cGMP-associated bovine pulmonary arterial relaxation.
Topics: Aminoquinolines; Animals; Anions; Cattle; Cyclic GMP; Ditiocarb; Hydrogen Peroxide; Hypoxia; Isoproterenol; Nitroglycerin; Oxygen; Oxygen Consumption; Pulmonary Artery; Superoxides; Vasodilation | 1990 |
Epithelium, contractile tone, and responses to relaxing agonists in canine bronchi.
Topics: Acetylcholine; Animals; Bronchi; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Epithelium; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroprusside; Serotonin | 1990 |
The Na+,K+,2Cl-cotransport system in HeLa cells: aspects of its physiological regulation.
Topics: Amino Acids; Atrial Natriuretic Factor; Biological Transport; Bumetanide; Carrier Proteins; Chlorides; Cyclic AMP; Cyclic GMP; HeLa Cells; Humans; Isoproterenol; Mannitol; Ouabain; Potassium; Rubidium; Sodium; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase | 1990 |
Inflammatory agonists that increase microvascular permeability in vivo stimulate cultured pulmonary microvessel endothelial cell contraction.
Topics: Angiotensin II; Animals; Bradykinin; Calcium; Capillary Permeability; Cattle; Cells, Cultured; Cyclic GMP; Edetic Acid; Endothelium, Vascular; Epoprostenol; Gallic Acid; Indomethacin; Intercellular Junctions; Isoproterenol; Myosin-Light-Chain Kinase; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Pulmonary Edema; Second Messenger Systems; Tetradecanoylphorbol Acetate; Thrombin; Trifluoperazine | 1990 |
Isoprenaline-like effects of the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine on mechanical, biochemical and electrophysiological parameters in the mammalian heart.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Calcium; Cyclic AMP; Cyclic GMP; Guinea Pigs; Heart; Ion Channels; Isoproterenol; Myocardial Contraction; Stimulation, Chemical; Theophylline | 1985 |
Ca2+-dependent modulation of renin release from isolated glomeruli: apparent independence from alterations in cGMP.
Topics: 1-Methyl-3-isobutylxanthine; Angiotensin II; Animals; Calcium; Calmodulin; Cyclic GMP; Female; In Vitro Techniques; Isoproterenol; Kidney Glomerulus; Nitroprusside; Ouabain; Potassium Chloride; Rats; Rats, Inbred Strains; Renin | 1985 |
Role of adenosine 3',5'-cyclic monophosphate in adrenoceptor-mediated control of 3H-noradrenaline secretion in guinea-pig ileum myenteric nerve terminals.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Male; Myenteric Plexus; Nerve Endings; Nicotinic Acids; Norepinephrine; Phosphodiesterase Inhibitors; Propranolol; Receptors, Adrenergic; Yohimbine | 1985 |
Augmentation of cholinergic-mediated amylase release by forskolin in mouse parotid gland.
Topics: Amylases; Animals; Calcimycin; Calcium; Carbachol; Colforsin; Cyclic GMP; Drug Synergism; Guanosine; Hydroxylamine; Hydroxylamines; Isoproterenol; Mice; Nitroprusside; Parasympathomimetics; Parotid Gland | 1985 |
BAY-K-8644-stimulated cyclic GMP synthesis in mouse pituitary tumor cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenocorticotropic Hormone; Animals; Azides; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Isoproterenol; Mice; Nifedipine; Nitroprusside; Pituitary Neoplasms; Sodium Azide; Stimulation, Chemical; Verapamil | 1986 |
Phosphodiesterase inhibitors induce endothelium-dependent relaxation of rat and rabbit aorta by potentiating the effects of spontaneously released endothelium-derived relaxing factor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta; Cyclic GMP; Drug Synergism; Endothelium; Hemoglobins; In Vitro Techniques; Isoproterenol; Male; Nitric Oxide; Nitroglycerin; Papaverine; Phosphodiesterase Inhibitors; Purinones; Rabbits; Rats; Rats, Inbred Strains; Vasodilation; Vasodilator Agents | 1986 |
Effects of cyclic nucleotide derivatives on acetylcholine-induced secretion from isolated, perfused rat submandibular salivary glands.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Bucladesine; Cyclic GMP; Isoproterenol; Male; Nucleotides, Cyclic; Rats; Rats, Inbred Strains; Saliva; Submandibular Gland; Theophylline | 1986 |
Parathyroid hormone-induced changes in cyclic nucleotide levels during relaxation of the rabbit [correction of rat] aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Parathyroid Hormone; Rabbits | 1987 |
Physiological effects of carbamylcholine, cyclic GMP and related agents on isolated rat ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Carbachol; Cells, Cultured; Cyclic AMP; Cyclic GMP; Electrophysiology; Heart; Heart Rate; Isoproterenol; Myocardial Contraction; Rats | 1987 |
Role of phosphodiesterase in regulation of calcium current in isolated cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Myocardium; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Ranidae | 1988 |
ANP relaxes bovine tracheal smooth muscle and increases cGMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Carbachol; Cattle; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Histamine; In Vitro Techniques; Isoproterenol; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Serotonin; Trachea | 1989 |
Methylene blue selectively inhibits pulmonary vasodilator responses in cats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Angiotensin II; Animals; Blood Pressure; Bradykinin; Cats; Cyclic GMP; Epinephrine; Female; Isoproterenol; Male; Methylene Blue; Nitroglycerin; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Circulation; Reference Values; Vasodilation | 1989 |
Atrial natriuretic peptide decreases contractility of cultured chick ventricular cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Atrial Natriuretic Factor; Calcium; Calcium Channels; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Heart; Heart Ventricles; Isoproterenol; Myocardial Contraction | 1989 |
A study of the phasic response of arterioles of the guinea pig small intestine to prolonged exposure to norepinephrine.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arterioles; Clonidine; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Intestine, Small; Isoproterenol; Membrane Potentials; Norepinephrine; Oxidation-Reduction; Propranolol; Temperature; Theophylline; Vasoconstriction; Yohimbine | 1989 |
Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition.
Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Carbamates; Cardiovascular Agents; Cyclic AMP; Cyclic GMP; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phosphodiesterase Inhibitors; Rabbits; Theophylline | 1989 |
Cyclic nucleotide regulation of neurotransmission in guinea pig mesenteric artery.
Topics: Animals; Colforsin; Cyclic GMP; Electrophysiology; Guinea Pigs; Isoproterenol; Male; Membrane Potentials; Mesenteric Arteries; Nucleotides, Cyclic; Phorbol Esters; Protein Kinase C; Second Messenger Systems; Synaptic Transmission | 1989 |
Modulation of the vasodilator action of SIN-1 by the endothelium.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Molsidomine; Nitric Oxide; Rabbits; Vasodilation; Vasodilator Agents | 1989 |
Insulin and lipolytic hormones stimulate the same phosphodiesterase isoform in rat adipose tissue.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cardiotonic Agents; Cyclic GMP; Enzyme Activation; Glucagon; Immunosorbent Techniques; Insulin; Isoenzymes; Isoproterenol; Kinetics; Lipolysis; Liver; Male; Rats; Rats, Inbred Strains | 1989 |
Biphasic forearm vascular responses to intraarterial arginine vasopressin.
Topics: Adult; Arginine Vasopressin; Biological Factors; Cyclic GMP; Forearm; Hemodynamics; Humans; Indomethacin; Infusions, Intra-Arterial; Isoproterenol; Nitric Oxide; Nitroprusside; Prostaglandins; Receptors, Angiotensin; Receptors, Vasopressin; Vasodilation | 1989 |
Cyclic GMP-dependent stimulation of the membrane-bound insulin-sensitive cAMP phosphodiesterase from rat adipocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Cyclic GMP; Dithiothreitol; Insulin; Isoproterenol; Kinetics; Male; Nucleotides, Cyclic; Rats; Rats, Inbred Strains; Ribonucleotides | 1989 |
Modulation of adenylate cyclase activity in bovine lens epithelial cells.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cattle; Cyclic AMP; Cyclic GMP; Epinephrine; Epithelial Cells; Fluorides; Insulin; Isoproterenol; Lens, Crystalline; Organ Culture Techniques; Phosphoric Diester Hydrolases | 1989 |
Endothelium-dependent relaxation and cyclic GMP accumulation in rabbit pulmonary artery are selectively impaired by moderate hypoxia.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Cyclic GMP; Endothelium, Vascular; Hypoxia; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Nitric Oxide; Nitroprusside; Pulmonary Artery; Rabbits; Receptors, Purinergic; Vasodilation | 1989 |
Subcellular localization and hormone sensitivity of adipocyte cyclic AMP phosphodiesterase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Cyclic GMP; Endoplasmic Reticulum; Enzyme Activation; Epinephrine; Glucagon; Insulin; Intracellular Membranes; Isoproterenol; Male; Protein Kinases; Rats; Rats, Inbred Strains | 1989 |
[Functional roles of cyclic AMP and cyclic GMP on rabbit urinary bladder and urethral smooth muscle contraction].
Topics: Animals; Cyclic AMP; Cyclic GMP; Female; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Rabbits; Urethra; Urinary Bladder | 1989 |
Injection of guanosine 5'-cyclic monophosphate into heart cells blocks calcium slow channels.
Topics: Action Potentials; Animals; Calcium; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic GMP; Electric Stimulation; Ion Channels; Isoproterenol; Myocardium; Nifedipine; Tetrodotoxin | 1985 |
Ethanol inhibits dual receptor stimulation of pineal cAMP and cGMP by vasoactive intestinal peptide and phenylephrine.
Topics: Alcohols; Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Female; In Vitro Techniques; Isoproterenol; Membrane Fluidity; Norepinephrine; Phenylephrine; Pineal Gland; Rats; Receptors, Adrenergic, alpha; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Vasoactive Intestinal Peptide | 1987 |
Role of cyclic AMP- and cyclic GMP-phosphodiesterases in the control of cyclic nucleotide levels and smooth muscle tone in rat isolated aorta. A study with selective inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta; Cyclic AMP; Cyclic GMP; Isoproterenol; Male; Muscle, Smooth, Vascular; Nitroprusside; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Vasoconstriction | 1987 |
Cyclic nucleotides depress action potentials in cultured aortic smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds | 1987 |
Effect of atrial natriuretic peptide on renin release in a superfusion system of kidney slices and dispersed juxtaglomerular cells.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cyclic GMP; Female; Isoproterenol; Juxtaglomerular Apparatus; Kidney Cortex; Perfusion; Rats; Rats, Inbred Strains; Renin | 1988 |
Changes in cyclic nucleotide levels during embryonic development of chick hearts.
Topics: Acetylcholine; Adenosine; Animals; Chick Embryo; Cyclic AMP; Cyclic GMP; Heart; Isoproterenol; Myocardium | 1987 |
Effects of protein kinase inhibitor (1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H7) on protein kinase C activity and adrenergic stimulation of cAMP and cGMP in rat pinealocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Isoproterenol; Isoquinolines; Norepinephrine; Pineal Gland; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic | 1988 |
Cyclic nucleotide- and calcium-dependent protein phosphorylation in rat pineal gland: physiological and pharmacological regulation.
Topics: Animals; Cyclic AMP; Cyclic GMP; Darkness; Isoproterenol; Light; Nerve Tissue Proteins; Phosphorylation; Pineal Gland; Protein Kinase C; Protein Kinases; Rats; Receptors, Adrenergic, beta | 1986 |
Inhibitory effect of analogues of cyclic nucleotides and cholera toxin on relaxin release from cultured porcine luteal cells.
Topics: Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Corpus Luteum; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprost; Female; Isoproterenol; Kinetics; Luteal Cells; Prostaglandins F; Relaxin; Swine | 1988 |
Relationship between LTD4-induced endothelium-dependent vasomotor relaxation and cGMP.
Topics: Acetylcholine; Animals; Cyclic GMP; Dogs; Endothelium, Vascular; Isoproterenol; Mesenteric Arteries; Methylene Blue; Nitroglycerin; Norepinephrine; SRS-A; Vasodilation; Vasomotor System | 1988 |
Alpha-1 adrenergic receptors on rabbit retinal pigment epithelium.
Topics: Animals; Clonidine; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Conductivity; Epinephrine; Isoproterenol; Phenylephrine; Pigment Epithelium of Eye; Prazosin; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Effects of colforsin, trequinsin and isoprenaline on norepinephrine-induced contractions and cyclic nucleotide levels of isolated vascular tissue.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Platelet Aggregation Inhibitors; Rabbits; Tetrahydroisoquinolines | 1988 |
Cyclic nucleotide interactions involved in endothelium-dependent dilatation in rat aortic rings.
Topics: Animals; Aorta, Thoracic; Biological Products; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Nitric Oxide; Nitroprusside; Nucleotides, Cyclic; Rats; Rats, Inbred Strains; Vasodilation | 1988 |
Inhibition of the low km cyclic AMP phosphodiesterase in intact canine trachealis by SK&F 94836: mechanical and biochemical responses.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bronchi; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Guanidines; Histamine; Isoproterenol; Kinetics; Methacholine Chloride; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Pyridazines; Trachea | 1988 |
The effects of aluminum on agonist-induced alterations in cyclic AMP and cyclic GMP concentrations in rat brain regions in vivo.
Topics: Aluminum; Animals; Apomorphine; Brain Chemistry; Cyclic AMP; Cyclic GMP; Drug Interactions; Isoproterenol; Male; Pilocarpine; Rats; Rats, Inbred Strains | 1988 |
Inhibition of cardiac slow action potentials by 8-bromo-cyclic GMP occurs independent of changes in cyclic AMP levels.
Topics: Action Potentials; Animals; Calcium; Cyclic AMP; Cyclic GMP; Electrophysiology; Female; Guinea Pigs; Heart; Isoproterenol; Male; Myocardium | 1988 |
Regulation of cytosolic calcium by cAMP and cGMP in freshly isolated smooth muscle cells from bovine trachea.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzofurans; Calcium; Calcium Channel Blockers; Carbachol; Cattle; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Cytosol; Fura-2; Isoproterenol; Muscle, Smooth; Pertussis Toxin; Tetradecanoylphorbol Acetate; Trachea; Virulence Factors, Bordetella | 1988 |
The human eccrine sweat gland adenylate cyclase system: response to agonists.
Topics: Adenylyl Cyclases; Adolescent; Adult; Autacoids; Bradykinin; Child; Cyclic AMP; Cyclic GMP; Eccrine Glands; Humans; In Vitro Techniques; Indomethacin; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Sweat Glands | 1985 |
Adrenergic-cholinergic interactions in left atria: interaction of carbachol with alpha- and beta-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Osmolar Concentration; Parasympathomimetics; Phenylephrine; Rabbits; Sympathomimetics | 1986 |
Guanosine 3',5'-cyclic monophosphate as a mediator of inhibition of renin release.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Atrial Natriuretic Factor; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Kidney Cortex; Kinetics; Methylene Blue; Nitroprusside; Rats; Renin | 1988 |
Effects of theophylline, beta-adrenergic stimulants and prednisolone on platelet and urine cyclic guanosine monophosphate (cGMP).
Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Aminophylline; Asthma; Blood Platelets; Cyclic GMP; Ethanolamines; Female; Humans; Isoproterenol; Male; Middle Aged; Prednisolone; Procaterol; Theophylline | 1988 |
Increased cyclic GMP levels lead to a stimulation of elastin production in ligament fibroblasts that is reversed by cyclic AMP.
Topics: Animals; Bucladesine; Calcium; Cattle; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Elastin; Female; Fibroblasts; Isoproterenol; Ligaments; Pregnancy | 1985 |
Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta.
Topics: Acetylcholine; Animals; Aorta; Blood Vessels; Calcimycin; Cyclic AMP; Cyclic GMP; Drug Interactions; Endothelium; Hemoglobins; In Vitro Techniques; Isoproterenol; Male; Methylene Blue; Nitroglycerin; Rabbits; Vasodilation | 1985 |
Cyclic nucleotides and contractility of isolated soleus muscle.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscles; Terbutaline | 1985 |
Nitroglycerine- and isoprenaline-induced vasodilatation: assessment from the actions of cyclic nucleotides.
Topics: Animals; Bucladesine; Caffeine; Calcium; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Potassium; Protein Kinases; Rabbits; Swine; Vasodilation | 1985 |
[Cyclic-nucleotides and adrenergic antiglaucoma drugs].
Topics: Animals; Aqueous Humor; Cyclic AMP; Cyclic GMP; Intraocular Pressure; Isoproterenol; Norepinephrine; Pupil; Rabbits; Timolol | 1985 |
Synthetic rat atrial natriuretic factor inhibits in vitro and in vivo renin secretion in rats.
Topics: Angiotensin I; Animals; Atrial Natriuretic Factor; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Isoproterenol; Kidney; Male; Muscle Proteins; Rats; Rats, Inbred Strains; Renin | 1985 |
Primary culture of ant venom gland cells.
Topics: Animals; Ants; Cattle; Cells, Cultured; Culture Media; Cyclic AMP; Cyclic GMP; Epidermal Growth Factor; Exocrine Glands; Fetal Blood; Fibroblast Growth Factors; Humans; Hydrogen-Ion Concentration; Insulin; Isoproterenol; Male; Osmotic Pressure; Rats; Rats, Inbred Strains; Venoms | 1985 |
Attenuation of muscarinic cholinergic inhibition by islet-activating protein in the heart.
Topics: Animals; Atrial Function; Bacterial Toxins; Carbachol; Cyclic AMP; Cyclic GMP; Drug Interactions; Electric Stimulation; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocardial Contraction; Myocardium; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Time Factors; Virulence Factors, Bordetella | 1985 |
Positive inotropic effect of acetylcholine in canine cardiac Purkinje fibers.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Calcium; Cyclic GMP; Dogs; Heart Conduction System; Isoproterenol; Membrane Potentials; Microelectrodes; Myocardial Contraction; Nitroprusside; Purkinje Fibers; Receptors, Muscarinic; Stimulation, Chemical; Verapamil | 1985 |
Beta-adrenergic mediators increase pulmonary retention of instilled phospholipids.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic GMP; Isoproterenol; Liposomes; Lung; Male; Propranolol; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Sucrose | 1985 |
Changes in cyclic AMP and cyclic GMP levels in the contraction-relaxation cycle of isolated smooth muscle cells from guinea-pig taenia caeci.
Topics: Animals; Caffeine; Colon; Cyclic AMP; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Propranolol | 1985 |
Calcitonin gene-related peptide stimulates cyclic AMP formation in rat aortic smooth muscle cells.
Topics: Animals; Atrial Natriuretic Factor; Calcimycin; Calcitonin Gene-Related Peptide; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Nerve Tissue Proteins; Nitroprusside; Phenylephrine; Rats; Rats, Inbred Strains | 1985 |
Biochemical changes accompanying enhanced cardiac contractility by ionophore A23187.
Topics: Animals; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Enzyme Activation; Guinea Pigs; Isoproterenol; Myocardial Contraction; Myocardium; Phosphates; Propranolol; Protein Kinases | 1985 |
Lymphocyte protein kinase activity in cells from young and elderly men and women.
Topics: Adult; Aged; Aging; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Propranolol; Protein Kinases; Sex Factors | 1985 |
See-saw signal processing in pinealocytes involves reciprocal changes in the alpha 1-adrenergic component of the cyclic GMP response and the beta-adrenergic component of the cyclic AMP response.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Isoproterenol; Kinetics; Light; Male; Nitroprusside; Norepinephrine; Periodicity; Phenylephrine; Pineal Gland; Quinacrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1986 |
Effect of age on the formation of cyclic nucleotides in guinea-pig tracheal smooth muscle in response to pharmacological agents.
Topics: Aging; Alprostadil; Animals; Carbachol; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Nitroprusside; Potassium; Trachea | 1986 |
Essential role of calcium influx in the adrenergic regulation of cAMP and cGMP in rat pinealocytes.
Topics: Animals; Calcimycin; Calcium; Cations; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Kinetics; Nifedipine; Norepinephrine; Ouabain; Pineal Gland; Rats; Rats, Inbred Strains | 1986 |
Lower esophageal sphincter relaxation is associated with increased cyclic nucleotide content.
Topics: Animals; Atrial Natriuretic Factor; Cyclic AMP; Cyclic GMP; Dopamine; Electric Stimulation; Esophagus; Female; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Opossums; Tetrodotoxin; Vasoactive Intestinal Peptide | 1986 |
Cyclic nucleotide-dependent protein kinases in the lower esophageal sphincter.
Topics: Adenosine Triphosphate; Animals; Cyclic AMP; Cyclic GMP; Dogs; Esophagus; Female; Humans; Isoproterenol; Kinetics; Male; Opossums; Protein Kinases | 1986 |
Cyclic nucleotide levels of the photosensitive irises of Bufo marinus and Lophius.
Topics: Animals; Bufo marinus; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Dark Adaptation; Fishes; Iris; Isoproterenol; Light | 1986 |
Protein kinase C is involved in adrenergic stimulation of pineal cGMP accumulation.
Topics: Animals; Calcimycin; Cyclic AMP; Cyclic GMP; Isoproterenol; Nifedipine; Ouabain; Pineal Gland; Potassium; Protein Kinase C; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1987 |
Proceedings: Cyclic GMP formation in human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Chromatography; Cyclic AMP; Cyclic GMP; Dithiothreitol; Dose-Response Relationship, Drug; Edetic Acid; Epinephrine; Guanylate Cyclase; Humans; In Vitro Techniques; Isoproterenol; Norepinephrine; Serotonin; Time Factors | 1974 |
Guanosine cyclic 3',5'-monophosphate and guanylate cyclase activity in guinea pig lung: effects of acetylcholine and cholinesterase inhibitors.
Topics: Acetylcholine; Animals; Chromatography, DEAE-Cellulose; Cyclic AMP; Cyclic GMP; Edrophonium; Epinephrine; Female; Guanylate Cyclase; Guinea Pigs; Isoproterenol; Lung; Neostigmine; Phentolamine; Physostigmine; Propranolol; Prostaglandins; Serotonin; Theophylline; Time Factors; Tritium | 1974 |
Glucose inhibition of epinephrine stimulation of hepatic gluconeogenesis by blockade of the alpha-receptor function.
Topics: Adrenergic alpha-Antagonists; Animals; Cyclic AMP; Cyclic GMP; Epinephrine; Fructose-Bisphosphatase; Fructosephosphates; Glucagon; Gluconeogenesis; Glucose; Guanine Nucleotides; In Vitro Techniques; Isoproterenol; Kinetics; Lactates; Liver; Phenoxybenzamine; Phosphofructokinase-1; Propranolol; Pyruvates; Rats; Stimulation, Chemical; Theophylline | 1974 |
Aberrations of cyclic nucleotide metabolism in the hearts and vessels of hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Desoxycorticosterone; Guanylate Cyclase; Hypertension; Isoproterenol; Mesenteric Arteries; Myocardium; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Rats; Stress, Physiological | 1974 |
Delayed increase of tyrosine hydroxylase activity induced by transsynaptic stimulation in chromaffin cells: role of cyclic nucleotides as second messengers.
Topics: Adrenal Glands; Adrenal Medulla; Adrenocorticotropic Hormone; Aminophylline; Animals; Carbachol; Chromaffin System; Cold Temperature; Cyclic AMP; Cyclic GMP; Dopamine beta-Hydroxylase; Electric Stimulation; Isoproterenol; Parasympathetic Nervous System; Physical Stimulation; Rats; Reserpine; Stimulation, Chemical; Stress, Physiological; Synapses; Time Factors; Tyrosine 3-Monooxygenase | 1974 |
Mechanism of action of some bronchodilators. Cyclic nucleotide metabolism in tracheal preparations.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Animals; Atropine; Bronchodilator Agents; Carbachol; Choline; Cyclic AMP; Cyclic GMP; Diphenhydramine; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Phenoxybenzamine; Phenylephrine; Practolol; Propranolol; Prostaglandins; Serotonin; Theophylline; Time Factors; Trachea | 1974 |
Cyclic adenosine monophosphate, cyclic guanosine monophosphate, and glucagon: effects on membrane potential and ion fluxes in the liver.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Glucagon; In Vitro Techniques; Isoproterenol; Liver; Membrane Potentials; Perfusion; Phentolamine; Potassium; Rats | 1971 |
[Influence of various hormones on formation of adenosine-3':5'-monophosphate and guanosine-3':5'-monophosphate by particulate preparations from rat kidney].
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Angiotensin II; Animals; Calcitonin; Cell Membrane; Cyclic AMP; Cyclic GMP; Diabetes Insipidus; Guanosine Triphosphate; Hormones; Isoproterenol; Kidney; Kidney Tubules; Magnesium; Male; Norepinephrine; Oxytocin; Parathyroid Hormone; Prostaglandins; Rats; Vasopressins; Water | 1972 |
Cyclic nucleotide-dependent protein kinases. X. An assay method for the measurement of quanosine 3',5'-monophosphate in various biological materials and a study of agents regulating its levels in heart and brain.
Topics: Acetylcholine; Animals; Bombyx; Brain; Cyclic AMP; Cyclic GMP; Depression, Chemical; Enzyme Activation; Glucagon; Heart Ventricles; Histamine; Humans; Isoproterenol; Male; Muscles; Myocardium; Nephropidae; Norepinephrine; Phosphotransferases; Proteins; Pupa; Rabbits; Rats; Stimulation, Chemical | 1972 |
Role of muscarinic cholinergic receptors in regulation of guanosine 3':5'-cyclic monophosphate content in mammalian brain, heart muscle, and intestinal smooth muscle.
Topics: Acetylcholine; Animals; Atropine; Bethanechol Compounds; Brain Chemistry; Cerebral Cortex; Cyclic GMP; Guinea Pigs; Heart; Heart Ventricles; Hexamethonium Compounds; Ileum; Isoproterenol; Muscle, Smooth; Myocardium; Parasympatholytics; Parasympathomimetics; Pilocarpine; Rabbits; Rats; Receptors, Cholinergic; Receptors, Drug; Tetraethylammonium Compounds; Tubocurarine | 1972 |
Adenylate cyclase from guinea pig lung: further characterization and inhibitory effects of substrate analogs and cyclic nucleotides.
Topics: Adenosine Triphosphatases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Bronchi; Cyclic AMP; Cyclic GMP; Drug Synergism; Fluorides; Guinea Pigs; Hydrogen-Ion Concentration; Isoproterenol; Kinetics; Lung; Magnesium; Male; Muscle, Smooth; Myocardium; Nucleosides; Nucleotides; Proteins; Purines; Sulfhydryl Compounds; Time Factors | 1973 |
Drug receptors and the haemopoietic stem cell.
Topics: Acetylcholine; Animals; Carbachol; Cell Division; Clone Cells; Cyclic GMP; DNA; Female; Hematopoietic Stem Cells; Imidazoles; Isoproterenol; Mice; Neostigmine; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Drug; Thymidine; Tritium; Tubocurarine | 1973 |
Schistosome motility measurements: response to drugs.
Topics: Amplifiers, Electronic; Animals; Carbachol; Catecholamines; Cyclic AMP; Cyclic GMP; Epinephrine; Fiber Optic Technology; Isoproterenol; Mice; Movement; Norepinephrine; Nucleotides; Pentobarbital; Physiology; Schistosoma mansoni; Serotonin; Statistics as Topic; Time Factors; Tryptophan | 1973 |
The modulating influence of cyclic nucleotides upon lymphocyte-mediated cytotoxicity.
Topics: Animals; Carbachol; Cholera; Cyclic AMP; Cyclic GMP; Cytotoxicity Tests, Immunologic; Graft Rejection; Imidazoles; Isoproterenol; Lymphocyte Depletion; Prostaglandins; Rats; T-Lymphocytes; Toxins, Biological | 1973 |
Release of enzymes from a rat liver lysosome fraction: inhibition by catecholamines and cyclic3', 5'-adenosine monophosphate, stimulation by cholinergic agents and cyclic 3', 5'-guanosine monophosphate.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Atropine; Carbachol; Catecholamines; Cyclic AMP; Cyclic GMP; Dihydroxyphenylalanine; Epinephrine; In Vitro Techniques; Isoproterenol; Liver; Lysosomes; Membranes; Methacholine Compounds; Norepinephrine; Parasympathomimetics; Phenylephrine; Phosphoric Diester Hydrolases; Phosphorus Isotopes; Rats; Reserpine; Stimulation, Chemical; Time Factors | 1973 |
Lymphocyte activation: the dualistic effect of cAMP.
Topics: Acetylcholine; Bromides; Butyrates; Cells, Cultured; Cyclic AMP; Cyclic GMP; DNA; Humans; Isoproterenol; Lectins; Lymphocytes; Prostaglandins; Time Factors; Tritium | 1973 |
Regulation by beta-adrenergic receptor and muscarinic cholinergic receptor activation of intracellular cyclic AMP and cyclic GMP levels in rat lung slices.
Topics: Acetylcholine; Animals; Cyclic AMP; Cyclic GMP; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Lung; Phenoxybenzamine; Propranolol; Protein Kinases; Rats; Receptors, Adrenergic; Receptors, Cholinergic | 1973 |
Mechanisms of lysosomal enzyme release from human leukocytes. II. Effects of cAMP and cGMP, autonomic agonists, and agents which affect microtubule function.
Topics: Atropine; Carbachol; Cholera; Colchicine; Cyclic AMP; Cyclic GMP; Cytochalasin B; Deuterium; Enterotoxins; Glucuronidase; Histamine; Humans; Isoproterenol; Leukocytes; Lysosomes; Phagocytosis; Phenylephrine; Propranolol; Prostaglandins; Zymosan | 1974 |
Effects of bradykinin and indomethacin on cyclic GMP and cyclic AMP in lung slices.
Topics: Acetylcholine; Angiotensin II; Animals; Aspirin; Bradykinin; Culture Techniques; Cyclic AMP; Cyclic GMP; Guinea Pigs; Histamine; Indomethacin; Isoproterenol; Lung; Peptides; Promethazine; Stimulation, Chemical; Theophylline | 1973 |
Leukocytes as secretory organs of inflammation.
Topics: Atropine; Blood Platelets; Bucladesine; Carbachol; Cell Survival; Cells, Cultured; Colchicine; Cyclic AMP; Cyclic GMP; Deuterium; Epinephrine; Glucuronidase; Histamine; Humans; Inflammation; Isoproterenol; Leukocytes; Lymphocytes; Monocytes; Peroxidases; Phenylephrine; Prostaglandins; Theophylline | 1973 |
Alteration of vein cyclic 3':5' nucleotide concentrations during changes in contractility.
Topics: Animals; Cattle; Cyclic AMP; Cyclic GMP; Dogs; Iodine Radioisotopes; Isoproterenol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Nucleotides, Cyclic; Phenylephrine; Prostaglandins; Radioimmunoassay; Vasoconstrictor Agents; Vasodilator Agents; Veins | 1974 |
Cyclic nucleotide levels during spontaneous uterine contractions.
Topics: Animals; Cyclic AMP; Cyclic GMP; Estrogens; Female; Isoproterenol; Muscle Contraction; Muscle, Smooth; Rats; Theophylline; Time Factors; Uterus | 1974 |
The effect of isoproterenol and its analogs upon adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate levels in mouse parotid gland in vivo. Relationship to the stimulation of DNA synthesis.
Topics: Acetylcholine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Atropine; Carbachol; Carbon Radioisotopes; Catecholamines; Cell Membrane; Chlorpromazine; Chromatography, Thin Layer; Cyclic AMP; Cyclic GMP; DNA; Enzyme Activation; Isoproterenol; Kinetics; Male; Mice; Mitosis; Nicotine; Parotid Gland; Phosphorus Radioisotopes; Propranolol; Structure-Activity Relationship; Thymidine; Time Factors; Tritium | 1974 |
The effect of catecholamine analogues upon amylase secretion from the mouse parotid gland in vivo:relationship to changes in cyclic AMP and cyclic GMP levels.
Topics: Amylases; Animals; Atropine; Cyclic AMP; Cyclic GMP; Isoproterenol; Male; Mice; Parotid Gland; Phentolamine; Propranolol; Reserpine; Structure-Activity Relationship; Time Factors | 1974 |
Modulation of polymorphonuclear leukocyte-mediated antibody-dependent cellular cytotoxicity.
Topics: Acetylcholine; Aminophylline; Animals; Antibodies; Carbachol; Cholera; Colchicine; Cyclic AMP; Cyclic GMP; Cytotoxicity Tests, Immunologic; Edetic Acid; Epinephrine; Humans; Imidazoles; Immune Adherence Reaction; Immune Sera; Isoproterenol; Leukemia, Experimental; Neutrophils; Propranolol; Rabbits; Toxins, Biological | 1974 |
Cyclic nucleotide hydrolysis: some possible natural regulators in retina and rod outer segments.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Ascorbic Acid; Calcium; Cattle; Centrifugation, Density Gradient; Cyclic AMP; Cyclic GMP; Diphosphates; Dithiothreitol; Dopamine; Epinephrine; Guanosine Triphosphate; Hydroxymercuribenzoates; Isoproterenol; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Photoreceptor Cells; Retina; Tritium | 1974 |
Enhancement of the radioprotective effects of 2-mercaptoethylamine on colony-forming cells by agents which alter cyclic nucleotide levels.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Clone Cells; Cyclic AMP; Cyclic GMP; Drug Synergism; Female; Imidazoles; In Vitro Techniques; Isoproterenol; Mercaptoethylamines; Mice; Prostaglandins; Radiation Effects; Radiation-Protective Agents; Theophylline | 1974 |
Effects of catecholamines and adrenergic-blocking agents on plasma and urinary cyclic nucleotides in man.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Catecholamines; Cyclic AMP; Cyclic GMP; Epinephrine; Heart Rate; Humans; Isoproterenol; Male; Norepinephrine; Phentolamine; Propranolol; Sympatholytics | 1972 |
Muscarinic regulation of phosphatidylinositol turnover and cyclic nucleotide metabolism in the heart.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Chickens; Cyclic AMP; Cyclic GMP; Heart; Heart Atria; Heart Ventricles; Isoproterenol; Mice; Myocardium; Parasympathomimetics; Phosphatidylinositols; Receptors, Muscarinic | 1984 |
Adenosine inhibition of catecholamine-induced increase in force of contraction in guinea-pig atrial and ventricular heart preparations. Evidence against a cyclic AMP- and cyclic GMP-dependent effect.
Topics: Adenosine; Adenylyl Cyclases; Animals; Calcium; Cyclic AMP; Cyclic GMP; Electric Stimulation; Guinea Pigs; Isoproterenol; Membrane Potentials; Myocardial Contraction | 1984 |
Cyclic nucleotide concentrations in tissue and perfusate of isolated rat lung.
Topics: Animals; Cyclic AMP; Cyclic GMP; DNA; In Vitro Techniques; Isoproterenol; Lung; Male; Perfusion; Positive-Pressure Respiration; Pulmonary Edema; Rats; Rats, Inbred Strains | 1984 |
[Biochemical aspects of enkephalin participation in the regulation of adrenergic effects on myocardium].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Creatine Kinase; Cyclic AMP; Cyclic GMP; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Heart; Isoenzymes; Isoproterenol; Magnesium; Male; Myocardium; Rabbits; Rats | 1984 |
The potentiating effect of an alpha-adrenergic blocking agent (E-643) on the action of bronchodilators.
Topics: Adrenergic alpha-Antagonists; Animals; Bronchodilator Agents; Cyclic AMP; Cyclic GMP; Drug Synergism; Epinephrine; Guinea Pigs; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Prostaglandins E; Quinazolines; Trachea | 1980 |
Patterns of cyclic nucleotides in normal and leukaemic human leucocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Carbachol; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Humans; Isoproterenol; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Serotonin; Theophylline | 1980 |
[Exogenous adrenergic stimulation by intravenous infusions of isoproterenol and blood levels of cyclic AMP before and after beta-blocking in humans].
Topics: Adrenergic beta-Antagonists; Adult; Cyclic AMP; Cyclic GMP; Ethanolamines; Female; Humans; Hypertension; Isoproterenol; Labetalol; Male; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sympathetic Nervous System | 1980 |
A diurnal rhythm in pineal protein 1 content mediated by beta-adrenergic neurotransmission.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Circadian Rhythm; Cyclic AMP; Cyclic GMP; Isoproterenol; Nerve Tissue Proteins; Norepinephrine; Organ Culture Techniques; Pineal Gland; Propranolol; Rats; Synapsins | 1982 |
Effect of sodium ions on cyclic AMP and cyclic GMP levels in mouse parotid acini.
Topics: Adrenergic beta-Agonists; Animals; Calcimycin; Carbachol; Cyclic AMP; Cyclic GMP; Isoproterenol; Kinetics; Mice; Monensin; Parotid Gland; Sodium | 1982 |
Neurohormonal receptors and cyclic AMP-binding proteins in rabbit tracheal mucosa-submucosa.
Topics: Adrenergic beta-Agonists; Animals; Carrier Proteins; Cyclic AMP; Cyclic AMP Receptor Protein; Cyclic GMP; Histamine; Isoproterenol; Kinetics; Male; Mucous Membrane; Rabbits; Receptors, Cell Surface; Receptors, Cyclic AMP; Trachea | 1982 |
Influence of isoproterenol and methylisobutylxanthine on the contractile and cyclic nucleotide effects of methacholine in isolated rat atria.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cyclic AMP; Cyclic GMP; Depression, Chemical; Drug Interactions; Female; Heart Atria; In Vitro Techniques; Isoproterenol; Methacholine Compounds; Myocardial Contraction; Ouabain; Rats; Stimulation, Chemical; Theophylline | 1980 |
Effects of isoprenaline and 1-methyl-3-isobutylxanthine on cyclic nucleotides and cyclic AMP-dependent protein kinase in rabbit colon smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colon; Cyclic AMP; Cyclic GMP; Isoproterenol; Muscle, Smooth; Protein Kinases; Rabbits; Sodium Fluoride; Theophylline | 1980 |
Cyclic nucleotides and amylase release from mouse and rabbit parotid acini.
Topics: Amylases; Animals; Carbachol; Cyclic AMP; Cyclic GMP; Isoproterenol; Mice; Parotid Gland; Rabbits; Time Factors | 1981 |
Reserpinization: effects on parotid gland function.
Topics: Amylases; Animals; Carbachol; Cyclic AMP; Cyclic GMP; Isoproterenol; Male; Mice; Mice, Inbred Strains; Parotid Gland; Rabbits; Receptors, Adrenergic, beta; Receptors, Cholinergic; Reserpine | 1984 |
Effect of substance P on exocrine secretion by rat submandibular gland cells.
Topics: Animals; Carboxylic Ester Hydrolases; Cells, Cultured; Cyclic AMP; Cyclic GMP; Isoproterenol; Male; Mucins; Norepinephrine; Rats; Rats, Inbred Strains; Submandibular Gland; Substance P | 1984 |
The interaction of relaxin with the rat uterus. I. Effect on cyclic nucleotide levels and spontaneous contractile activity.
Topics: Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Estradiol; Female; In Vitro Techniques; Isoproterenol; Kinetics; Muscle Contraction; Propranolol; Rats; Relaxin; Uterus | 1980 |
Ectopic alpha-adrenergic mediated accumulation of guanosine 3',5'-monophosphate in isolated adrenocortical carcinoma cells.
Topics: Acetylcholine; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Animals; Atropine; Cell Line; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Epinephrine; Isoproterenol; Phentolamine; Phenylephrine; Propranolol; Rats | 1980 |
Protein phosphorylation in human peripheral blood lymphocytes: mitogen-induced increases in protein phosphorylation in intact lymphocytes.
Topics: Adenosine Triphosphate; Buffers; Chemistry, Organic; Concanavalin A; Cyclic AMP; Cyclic GMP; Humans; Hydrolysis; Isoproterenol; Lymphocytes; Mitogens; Nitroprusside; Organic Chemistry Phenomena; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Prostaglandins E; Protein Kinases; Sonication; Time Factors | 1980 |
Local analgesic effect of morphine on the hyperalgesia induced by cAMP, Ca2+, isoprenaline, and PGE2.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Enkephalins; Humans; Hyperalgesia; Hyperesthesia; Isoproterenol; Morphine; Nociceptors; Prostaglandin Antagonists; Prostaglandins E; Synaptic Transmission | 1980 |
Thyroxine-induced changes in characteristics and activities of beta-adrenergic receptors and adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate systems in the heart may be related to reputed catecholamine supersensitivity in hyperthyroidism.
Topics: Adenylyl Cyclases; Animals; Cardiomegaly; Cyclic AMP; Cyclic GMP; Dihydroalprenolol; Fluorides; Heart; Hyperthyroidism; Isoproterenol; Kinetics; Male; Myocardium; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Thyroxine | 1980 |
The time course of changes in cyclic nucleotide levels during cholinergic inhibition of positive inotropic actions of isoprenaline and theophylline in the isolated canine ventricular myocardium.
Topics: Animals; Atropine; Carbachol; Cyclic AMP; Cyclic GMP; Dogs; Drug Interactions; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Pindolol; Stimulation, Chemical; Theophylline; Time Factors; Ventricular Function | 1980 |
Cyclic nucleotides, beta receptors, and bronchial asthma.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Albuterol; Asthma; Bronchi; Cyclic AMP; Cyclic GMP; Epinephrine; Humans; Hydrocortisone; Isoproterenol; Lymphocytes; Norepinephrine; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1980 |
Adrenergic and cholinergic modulation of extracellular cyclic nucleotides.
Topics: Acetylcholine; Animals; Blood Pressure; Catecholamines; Cyclic AMP; Cyclic GMP; Epinephrine; Humans; Hyperthyroidism; Hypothyroidism; Insulin; Isoproterenol; Physical Exertion; Propranolol; Rats; Stress, Physiological; Tyramine | 1980 |
Cyclic nucleotides in diabetes mellitus and obesity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Cyclic AMP; Cyclic GMP; Diabetes Mellitus; Diabetes Mellitus, Experimental; Epinephrine; Glucagon; Humans; Insulin; Isoproterenol; Liver; Male; Mice; Mice, Obese; Obesity; Rats | 1980 |
Epinephrine-stimulated phosphorylation of pyruvate kinase in hepatocytes.
Topics: Animals; Cyclic AMP; Cyclic GMP; Epinephrine; In Vitro Techniques; Isoproterenol; Kinetics; Liver; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Phosphorylation; Propranolol; Pyruvate Kinase; Rats | 1980 |
Acetylcholine modulation of phosphorylase and contractility in rat hearts exposed to anoxia or isoproterenol.
Topics: Acetylcholine; Animals; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Oxygen; Phosphorylases; Protein Kinases; Rats; Time Factors | 1980 |
Interaction between alpha and beta adrenergic receptors and cholinergic receptors in isolated perfused rat heart: effects on cAMP-protein kinase and phosphorylase.
Topics: Acetylcholine; Animals; Cyclic AMP; Cyclic GMP; Epinephrine; Isoproterenol; Male; Myocardial Contraction; Myocardium; Phentolamine; Phosphorylases; Rats; Receptors, Adrenergic; Receptors, Cholinergic | 1980 |
Properties of cardiac contractions in zero sodium solutions: intracellular free calcium controls slow channel conductance.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Egtazic Acid; Electric Stimulation; Guinea Pigs; Ion Exchange; Isoproterenol; Male; Myocardial Contraction; Rats; Sodium; Species Specificity; Strontium | 1980 |
Adrenergic and cholinergic regulation of lung surfactant secretion in the isolated perfused rat lung and in the alveolar type II cell in culture.
Topics: Acetylcholine; Alprenolol; Animals; Atropine; Cells, Cultured; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Kinetics; Lung; Male; Perfusion; Phentolamine; Phenylephrine; Pulmonary Alveoli; Pulmonary Surfactants; Rats | 1981 |
Lymphokine-induced Macrophage aggregation: the possible role of cyclic nucleotides.
Topics: Bucladesine; Carbachol; Cell Aggregation; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Humans; In Vitro Techniques; Isoproterenol; Lymphokines; Macrophages | 1980 |
Cyclic nucleotides of canine antral smooth muscle. Effects of acetylcholine, catecholamines and gastrin.
Topics: Acetylcholine; Animals; Catecholamines; Cyclic AMP; Cyclic GMP; Dogs; Female; Gastrins; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Nitroprusside; Norepinephrine; Pyloric Antrum; Sodium Fluoride | 1981 |
Relaxing effect of pharmacologic interventions increasing cAMP in rat heart.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Depression, Chemical; Glucagon; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Norepinephrine; Ouabain; Protein Kinases; Rats | 1981 |
Ca++ inhibition of isoproterenol responses in mammalian skeletal muscle.
Topics: Animals; Calcium; Cations, Divalent; Cyclic GMP; Enzyme Activation; In Vitro Techniques; Isoproterenol; Male; Mice; Muscles; Phosphorylase a; Phosphorylase Kinase | 1981 |
Regulation by a beta-adrenergic receptor of a Ca2+-independent adenosine 3',5'-(cyclic)monophosphate phosphodiesterase in C6 glioma cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calmodulin; Cell Line; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Glioma; Isoenzymes; Isoproterenol; Kinetics; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Subcellular Fractions | 1981 |
Selective phosphodiesterase inhibition and alterations of cardiac function by alkylated xanthines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic AMP; Cyclic GMP; Female; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Rabbits; Xanthines | 1981 |
Xanthine derivatives that selectively inhibit cyclic GMP hydrolysis potentiate cardiac contractile effects of isoproterenol but not those of bethanecol.
Topics: Animals; Bethanechol Compounds; Cyclic AMP; Cyclic GMP; Female; Heart; Hydrolysis; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Rabbits; Xanthines | 1981 |
Load-dependent activation of calcium turnover and cardiac performance in isolated rat atria.
Topics: Animals; Blood Pressure; Calcium; Cyclic AMP; Cyclic GMP; Heart Atria; Indomethacin; Isoproterenol; Male; Myocardial Contraction; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains | 1981 |
Hormonal control of phosphodiesterase activity in cultured rat Sertoli cells.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Follicle Stimulating Hormone; Isoproterenol; Magnesium; Male; Rats; Sertoli Cells | 1981 |
Modulatory role of cyclic AMP in the release of platelet-activating factor from human polymorphonuclear leucocytes.
Topics: Blood Coagulation Factors; Blood Platelets; Cyclic AMP; Cyclic GMP; Epinephrine; Glucuronidase; Humans; Isoproterenol; Lysophosphatidylcholines; Phosphodiesterase Inhibitors; Pilocarpine; Platelet Activating Factor; Platelet Aggregation; Zymosan | 1982 |
Phorbol myristate acetate uncouples the relationship between beta-adrenergic receptors and adenyl cyclase in mouse epidermis: a phenotypic trait in papillomas.
Topics: Adenylyl Cyclases; Animals; Cocarcinogenesis; Cyclic GMP; Enzyme Activation; Epidermis; Isoproterenol; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Mechanisms of human cell-mediated cytotoxicity. I. Modulation of natural killer cell activity by cyclic nucleotides.
Topics: Aminophylline; Atropine; Bucladesine; Carbachol; Cell Survival; Cyclic GMP; Cytotoxicity, Immunologic; Dibutyryl Cyclic GMP; Histamine; Humans; Incubators; Isoproterenol; Kinetics; Lymphocytes; Nucleotides, Cyclic; Propranolol | 1982 |
Positive inotropic effect of amrinone in relation to cyclic nucleotide metabolism in the canine ventricular muscle.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Amrinone; Animals; Carbachol; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Dogs; Drug Interactions; Female; In Vitro Techniques; Isoproterenol; Male; Myocardium; Time Factors | 1982 |
Acetylcholine inhibits positive inotropic effect of cholera toxin in ventricular muscle.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Chick Embryo; Cholera Toxin; Cyclic AMP; Cyclic GMP; Heart Ventricles; Isoproterenol; Myocardial Contraction; Stimulation, Chemical; Time Factors | 1982 |
Inhibition of the Na+/K+ cotransport system by cyclic AMP and intracellular Ca2+ in human red cells.
Topics: Biological Transport, Active; Calcium; Cyclic AMP; Cyclic GMP; Erythrocyte Membrane; Erythrocytes; Humans; Isoproterenol; Potassium; Receptors, Adrenergic; Sodium | 1982 |
Influence of cyclic nucleotides on the internal longitudinal resistance and contractures in the normal and hypoxic mammalian cardiac muscle.
Topics: Acetylcholine; Animals; Bucladesine; Cats; Cyclic GMP; Electric Conductivity; Electrophysiology; Heart; Hypoxia; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Nucleotides, Cyclic | 1982 |
Muscarinic cholinergic receptors on cultured thyroid cells. I. Biological effect of carbachol and characterization of the receptors.
Topics: Animals; Carbachol; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dinoprostone; In Vitro Techniques; Isoproterenol; Prostaglandins E; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic; Swine; Thyroid Gland; Thyrotropin | 1982 |
Cyclic nucleotide response to stimulation in isolated glomeruli from dog kidney.
Topics: Animals; Biogenic Amines; Cyclic AMP; Cyclic GMP; Dogs; Dopamine; Epinephrine; Histamine; In Vitro Techniques; Isoproterenol; Kidney Glomerulus; Norepinephrine; Propranolol | 1982 |
Potentiation of the effects of sodium nitroprusside and of isoproterenol by selective phosphodiesterase inhibitors.
Topics: Animals; Calmodulin; Cattle; Chromatography, DEAE-Cellulose; Coronary Vessels; Cyclic AMP; Cyclic GMP; Drug Synergism; Ferricyanides; Isoproterenol; Muscle Relaxation; Nitroprusside; Phosphodiesterase Inhibitors; Potassium | 1983 |
Hydrocortisone and isoproterenol effects on trachealis cAMP and relaxation.
Topics: Analysis of Variance; Animals; Cyclic AMP; Cyclic GMP; Dogs; Hydrocortisone; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Trachea | 1983 |
Forskolin, cyclic nucleotides and positive inotropism in isolated papillary muscles of the rabbit.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitroprusside; Papillary Muscles; Rabbits | 1984 |
Influence of calcium and cyclic nucleotides on beta-adrenergic sweat secretion in equine sweat glands.
Topics: Animals; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Edetic Acid; Ion Channels; Isoproterenol; Perissodactyla; Propranolol; Receptors, Adrenergic, beta; Stimulation, Chemical; Sweat; Sweat Glands; Verapamil | 1984 |
A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Arginine; Carbachol; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Heart Rate; Isoproterenol; Methylene Blue; Molsidomine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Sinoatrial Node; Thionucleotides | 1995 |
Relaxant mechanisms of cyclic AMP-increasing agents in porcine coronary artery.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Ethanolamines; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Ryanodine; Swine; Thromboxane A2; Vasodilator Agents | 1994 |
Cross talk among cyclic AMP, cyclic GMP, and Ca(2+)-dependent intracellular signalling mechanisms in brain capillary endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Capillaries; Cells, Cultured; Cerebrovascular Circulation; Colforsin; Cyclic AMP; Cyclic GMP; Endothelins; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; Intracellular Membranes; Isoproterenol; Rats; Receptors, Endothelin; Signal Transduction | 1994 |
Influence of atrial natriuretic peptide on cyclic nucleotides and amylase release in rat parotid salivary gland in vitro.
Topics: Amylases; Animals; Atrial Natriuretic Factor; Bucladesine; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Isoproterenol; Male; Nitroprusside; Parotid Gland; Rats; Rats, Wistar; Stimulation, Chemical | 1994 |
Atrial natriuretic peptide reduces cyclic AMP by activating cyclic GMP-stimulated phosphodiesterase in vascular endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclases; Animals; Aorta; Atrial Natriuretic Factor; Cattle; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Isoenzymes; Isoproterenol; Isoquinolines; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Tetrahydroisoquinolines | 1994 |
Tyrosine kinase inhibitors enhance cGMP production in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Catechols; Cyclic AMP; Cyclic GMP; Genistein; Hydroquinones; Isoflavones; Isoproterenol; Male; Nitric Oxide Synthase; Nitriles; Norepinephrine; omega-N-Methylarginine; Pineal Gland; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrphostins | 1995 |
Phosphatase inhibitors potentiate adrenergic-stimulated cAMP and cGMP production in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antifungal Agents; Cyclic AMP; Cyclic GMP; Drug Synergism; Ethers, Cyclic; Isoproterenol; Kinetics; Male; Marine Toxins; Norepinephrine; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Pineal Gland; Protein Phosphatase 2; Pyrans; Rats; Rats, Sprague-Dawley; Spiro Compounds | 1995 |
Role of nitric oxide and cAMP in beta-adrenoceptor-induced pial artery vasodilation.
Topics: Albuterol; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Dobutamine; Enzyme Activation; Female; Isoproterenol; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Pia Mater; Receptors, Adrenergic, beta; Swine; Vasodilation | 1995 |
Autonomic regulation of cardiac chloride current.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Autonomic Agents; Chloride Channels; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Isoproterenol | 1994 |
Insulin stimulates hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase in rat brown adipose cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Adipose Tissue, Brown; Amino Acid Sequence; Animals; Cyclic GMP; DNA, Complementary; Hormones; Insulin; Isoproterenol; Male; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1995 |
The effect of NO-donors in bovine and rat pineal cells: stimulation of cGMP and cGMP-independent inhibition of melatonin synthesis.
Topics: Animals; Cattle; Cells, Cultured; Cyclic GMP; Isoproterenol; Melatonin; Molsidomine; Nitric Oxide; Nitroprusside; Pineal Gland; Rats; Stimulation, Chemical | 1995 |
Role of CNP in human airways: cGMP-mediated stimulation of ciliary beat frequency.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Adolescent; Adult; Atrial Natriuretic Factor; Cells, Cultured; Cilia; Cyclic GMP; Epithelium; Female; Humans; Isoproterenol; Kinetics; Male; Middle Aged; Movement; Nasal Mucosa; Natriuretic Peptide, C-Type; Nitroprusside; Proteins; Time Factors | 1995 |
Reversal of radiation-induced cisplatin resistance in murine fibrosarcoma cells by selective modulation of the cyclic GMP-dependent transduction pathway.
Topics: Animals; Cell Survival; Cisplatin; Combined Modality Therapy; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Drug Resistance; Fibrosarcoma; Isoproterenol; Mice; Phosphodiesterase Inhibitors; Signal Transduction; Tumor Cells, Cultured | 1995 |
Generation of cyclic guanosine monophosphate in brain slices incubated with atrial or C-type natriuretic peptides: comparison of the amplitudes and cellular distribution of the responses.
Topics: Animals; Atrial Natriuretic Factor; Brain; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Microtomy; Natriuretic Peptide, C-Type; Proteins; Rats; Rats, Sprague-Dawley | 1995 |
Direct action of endotoxin on cardiac muscle.
Topics: Animals; Calcium Chloride; Cats; Cyclic GMP; Endotoxins; Female; Heart; Infusions, Intravenous; Isoproterenol; Male; Myocardial Contraction; Organ Size; Papillary Muscles | 1995 |
Cyclic GMP-mediated phospholamban phosphorylation in intact cardiomyocytes.
Topics: Animals; Atrial Natriuretic Factor; Calcium-Binding Proteins; Cells, Cultured; Cyclic GMP; Heart; Isoproterenol; Myocardium; Nitroprusside; Phosphorylation; Rats; Rats, Wistar | 1995 |
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Heart; Heart Rate; Heart Ventricles; Isoproterenol; Methylene Blue; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxyhemoglobins; Rats; Signal Transduction | 1993 |
Isoprenaline induces endothelium-independent relaxation and accumulation of cyclic nucleotides in the rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Wistar | 1994 |
Protamine does not affect the formation of cGMP or cAMP in pig vascular smooth muscle cells in response to vasodilators.
Topics: Analysis of Variance; Animals; Atrial Natriuretic Factor; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Muscle, Smooth, Vascular; Nitroprusside; Prospective Studies; Protamines; Swine; Vasodilator Agents | 1995 |
Potentiating effect of nicorandil, an antianginal agent, on relaxation induced by isoproterenol in isolated rat aorta: involvement of cyclic GMP-inhibitable cyclic AMP phosphodiesterase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Angina Pectoris; Animals; Aorta; Cyclic AMP; Cyclic GMP; Drug Synergism; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Rats; Rats, Wistar; Vasodilator Agents | 1995 |
C-natriuretic peptide but not atrial natriuretic peptide increases cyclic GMP in cerebral arterial smooth muscle cells.
Topics: Animals; Atrial Natriuretic Factor; Cells, Cultured; Cerebral Arteries; Colforsin; Coronary Vessels; Cyclic GMP; Female; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Natriuretic Peptide, C-Type; Proteins; Swine | 1995 |
Lung transplantation with cardiopulmonary bypass exaggerates pulmonary vasomotor dysfunction in the transplanted lung.
Topics: Acetylcholine; Animals; Cardiopulmonary Bypass; Cyclic AMP; Cyclic GMP; Dogs; Endothelium, Vascular; Isoproterenol; Lung Transplantation; Muscle, Smooth, Vascular; Nitroprusside; Organ Preservation; Pulmonary Artery; Time Factors; Vascular Resistance; Vasomotor System | 1995 |
Nitric oxide regulates the calcium current in isolated human atrial myocytes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anura; Calcium Channels; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Female; Heart; Heart Atria; Humans; Isoproterenol; Kinetics; Male; Membrane Potentials; Middle Aged; Milrinone; Molsidomine; Nitric Oxide; Patch-Clamp Techniques; Pyridones; Time Factors; Vasodilator Agents | 1995 |
Selective inhibition of cyclic adenosine monophosphate-mediated pulmonary vasodilation by acute hypoxia.
Topics: Acetylcholine; Acute Disease; Animals; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Hypoxia; In Vitro Techniques; Isoproterenol; Lung; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Sprague-Dawley; Vasodilation | 1995 |
Mechanisms of cyclic nucleotide-induced relaxation in canine tracheal smooth muscle.
Topics: Adenylyl Cyclases; Animals; Calcium Channels; Calcium-Transporting ATPases; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Female; Indoles; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium Chloride; Sarcoplasmic Reticulum; Trachea | 1995 |
Nitric oxide regulates cardiac Ca2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation.
Topics: Animals; Calcium Channels; Colforsin; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Heart Ventricles; In Vitro Techniques; Isoproterenol; Molsidomine; Nitric Oxide; Phosphoric Diester Hydrolases; Rana esculenta | 1993 |
Pulmonary vascular smooth muscle relaxation by cGMP- versus cAMP-mediated mechanisms.
Topics: Alprostadil; Amrinone; Analysis of Variance; Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Nitroprusside; Phosphodiesterase Inhibitors; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Prostaglandin E; Vasodilation; Vasodilator Agents | 1994 |
Inhibitory effect of sodium nitroprusside on the relaxing action of isoproterenol in isolated rat urinary bladder.
Topics: Animals; Cyclic GMP; Dobutamine; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Methylene Blue; Muscle Relaxation; Nitroprusside; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Urinary Bladder | 1994 |
Natriuretic peptide clearance receptor is transcriptionally down-regulated by beta 2-adrenergic stimulation in vascular smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Antagonists; Amino Acid Sequence; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Blotting, Northern; Blotting, Western; Cell Membrane; Cells, Cultured; Colforsin; Cyclic GMP; Down-Regulation; Gene Expression; Guanylate Cyclase; Isoproterenol; Kinetics; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Norepinephrine; Propanolamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Sodium Fluoride | 1994 |
Effects of thyroid hormone on the calcium current and isoprenaline-induced background current in rabbit ventricular myocytes.
Topics: Acetylcholine; Animals; Calcium; Cyclic AMP; Cyclic GMP; Heart Ventricles; In Vitro Techniques; Isoproterenol; Rabbits; Triiodothyronine | 1994 |
Synergistic action of vasodilators that increase cGMP and cAMP in the hamster cremaster microcirculation.
Topics: Abdomen; Animals; Cricetinae; Cyclic AMP; Cyclic GMP; Drug Synergism; Epoprostenol; Isoproterenol; Male; Mesocricetus; Microcirculation; Muscle, Smooth; Nitroprusside; Stimulation, Chemical; Vasodilator Agents | 1994 |
Lack of importance of NO in beta-adrenoceptor-mediated relaxation of large epicardial canine coronary arteries.
Topics: Animals; Arginine; Coronary Vessels; Cyclic GMP; Dogs; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptors, Adrenergic, beta; Vasodilation | 1994 |
Mechanisms of coronary vasomotor dysfunction in the transplanted heart.
Topics: Acetylcholine; Animals; Cold Temperature; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dogs; Endothelium, Vascular; Female; Heart Transplantation; Isoproterenol; Male; Myocardial Reperfusion Injury; Nitroprusside; Vasomotor System | 1994 |
Developmental appearance of pineal adrenergic-->guanosine 3',5'-monophosphate response is determined by a process down-stream from elevation of intracellular Ca2+: possible involvement of a diffusible factor.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenal Glands; Aging; Animals; Arachidonic Acid; Calcium; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cytosol; Guanylate Cyclase; Isoproterenol; Kinetics; Mice; Norepinephrine; Organ Culture Techniques; Phospholipases A; Phospholipases A2; Pineal Gland; Potassium; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1993 |
Effect of flosequinan on ischaemia-induced arrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Enzyme Activation; Isoproterenol; Male; Milrinone; Myocardial Ischemia; Myocardium; Phosphodiesterase Inhibitors; Pyridones; Quinolines; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
Synergistic inhibitory effects of atriopeptin II and isoproterenol on contraction of rat aortic smooth muscle: roles of cGMP and cAMP.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cyclic AMP; Cyclic GMP; Drug Synergism; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth, Vascular; Peptide Fragments; Rats; Rats, Inbred WKY; Vasoconstriction | 1993 |
Regulation of Ca2+ channels by cAMP and cGMP in vascular smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; Electrophysiology; Isoproterenol; Muscle, Smooth, Vascular; Nucleotides, Cyclic; Osmolar Concentration; Rabbits | 1993 |
Isoproterenol- and insulin-induced hyperpolarization in rat skeletal muscle.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Insulin; Isoproterenol; Male; Membrane Potentials; Muscles; Ouabain; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1993 |
The enhancement of catecholamine-induced Cl- current by cyclic GMP revealed using photolabile caged compounds in guinea-pig ventricular cells.
Topics: Animals; Calcium; Cells, Cultured; Chlorides; Cyclic GMP; Guinea Pigs; Heart Ventricles; Isoproterenol; Myocardium; Photochemistry | 1993 |
Protein phosphorylation and cardiac function: cholinergic-adrenergic interaction.
Topics: Animals; Calcium-Binding Proteins; Carbachol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitroprusside; Perfusion; Phosphorylase a; Phosphorylation; Proteins; Rats; Rats, Wistar; Troponin; Troponin I | 1993 |
CD-832, a new dihydropyridine derivative with both nitrate-like and Ca2+ channel antagonist vasodilator activities.
Topics: Animals; Aorta, Thoracic; Brain Chemistry; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nifedipine; Nitrates; Rabbits; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
Measurement of both cyclic [3H]AMP and cyclic [3H]GMP in cultured vascular smooth muscle cells labeled with [3H]hypoxanthine: use in studies of cardiovascular drugs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Triphosphate; Animals; Cardiovascular Agents; Cells, Cultured; Cyclic AMP; Cyclic GMP; Drug Evaluation, Preclinical; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Isoproterenol; Isotope Labeling; Muscle, Smooth, Vascular; Nitroprusside; Radioimmunoassay; Rats; Rats, Inbred WKY; Reproducibility of Results; Tritium | 1993 |
Isoproterenol changes the relationship between cytosolic Ca2+ and contraction in guinea pig taenia caecum.
Topics: Animals; Calcium; Cecum; Cyclic AMP; Cyclic GMP; Cytosol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Potassium; Receptors, Adrenergic, beta | 1993 |
Involvement of endothelium-derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney.
Topics: Acetylcholine; Angiotensin I; Animals; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Diuresis; In Vitro Techniques; Isoproterenol; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Perfusion; Pressure; Rats; Rats, Inbred Strains; Renin | 1993 |
Activation of distinct cAMP- and cGMP-dependent pathways by relaxant agents in isolated gastric muscle cells.
Topics: Aminoquinolines; Animals; Arginine; Cell Separation; Colon; Cyclic AMP; Cyclic GMP; Digestive System; Digestive System Physiological Phenomena; Enzyme Activation; Gastric Fundus; Guinea Pigs; Isoproterenol; Muscle Relaxation; Muscles; Nitrates; Nitric Acid; Nitroarginine; Nitroprusside; Protein Kinase C; SRS-A; Vasoactive Intestinal Peptide | 1993 |
Inhibition of IP3 and IP3-dependent Ca2+ mobilization by cyclic nucleotides in isolated gastric muscle cells.
Topics: Animals; Calcium; Calcium Radioisotopes; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Sincalide; Stomach; Vasoactive Intestinal Peptide | 1993 |
Stimulation of the slow calcium current in bullfrog skeletal muscle fibers by cAMP and cGMP.
Topics: Animals; Calcium Channels; Cyclic AMP; Cyclic GMP; Electric Conductivity; Electric Stimulation; Isoproterenol; Muscles; Rana catesbeiana | 1993 |
Comparative effects of activation of soluble and particulate guanylyl cyclase on cyclic GMP elevation and relaxation of bovine tracheal smooth muscle.
Topics: Animals; Atrial Natriuretic Factor; Cattle; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Histamine; In Vitro Techniques; Isoproterenol; Male; Methacholine Compounds; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Nitric Oxide; Receptors, Muscarinic; Trachea | 1995 |
Pulmonary vasomotor dysfunction is produced with chronically high pulmonary blood flow.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Arteriovenous Shunt, Surgical; Blood Vessel Prosthesis; Cyclic AMP; Cyclic GMP; Dogs; Endothelium, Vascular; Femoral Artery; Femoral Vein; Hypertension, Pulmonary; Isoproterenol; Male; Nitroprusside; Polytetrafluoroethylene; Pulmonary Artery; Pulmonary Circulation; Time Factors; Vasoconstriction; Vasodilator Agents; Vasomotor System | 1996 |
Inotropic and chronotropic effects of 4-(4'-n-butylaniline)-7,8- dimethoxy-5H-pyrimido[5,4-b]indole in guinea-pig atria.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Antagonists; Amrinone; Animals; Carbachol; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; Indoles; Isoenzymes; Isoproterenol; Male; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyrimidines | 1995 |
Evidence against a role of nitric oxide in the indirect negative inotropic-effect of M-cholinoceptor stimulation in human ventricular myocardium.
Topics: Arginine; Carbachol; Cyclic GMP; Humans; Isoproterenol; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Papillary Muscles; Receptors, Cholinergic | 1995 |
cGMP elevation does not mediate muscarinic agonist-induced negative inotropy in rat ventricular cardiomyocytes.
Topics: Animals; Carbachol; Cell Separation; Cyclic AMP; Cyclic GMP; Isoproterenol; Male; Muscarinic Agonists; Myocardial Contraction; Myocardium; Nitroprusside; Rats; Rats, Wistar; Ventricular Function | 1995 |
Specific potentiation by cyclic AMP of natriuretic peptide-mediated cyclic GMP production in adipose tissue.
Topics: 3T3 Cells; Adipose Tissue; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Cyclic GMP; Isoproterenol; Mice; Natriuretic Peptide, C-Type; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor | 1996 |
Magnesium is essential in mechanisms of pulmonary vasomotor control.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Kinetics; Magnesium; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasodilation | 1996 |
Selective effect of high arterial pressure in hypertension upon inhibition of cGMP versus cAMP mediated vascular relaxation.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Pressure; Bucladesine; Cyclic AMP; Cyclic GMP; Hypertension, Renovascular; In Vitro Techniques; Isoproterenol; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Vasodilation | 1996 |
Inhibition of beta- but not alpha 1-mediated adrenergic responses in isolated hearts and cardiomyocytes by nitric oxide and 8-bromo cyclic GMP.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium; Cell Size; Cells, Cultured; Cyclic GMP; Isoproterenol; Male; Molsidomine; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Perfusion; Phenylephrine; Propranolol; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Stimulation, Chemical; Vasodilator Agents | 1996 |
Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3.
Topics: Adrenergic beta-Agonists; Allopurinol; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Phosphodiesterase Inhibitors; Rats; Vasodilator Agents | 1996 |
Studies on the influence of insulin on cyclic adenosine monophosphate in human vascular smooth muscle cells: dependence on cyclic guanosine monophosphate and modulation of catecholamine effects.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Analysis of Variance; Arterioles; Cells, Cultured; Cyclic AMP; Cyclic GMP; Epinephrine; Humans; Insulin; Isoproterenol; Kinetics; Methylene Blue; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Propranolol; Receptors, Adrenergic, beta; Recombinant Proteins; Yohimbine | 1996 |
ANP-stimulated cGMP egression in renal principal cells: abrogation of polarity by SV40 large T.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antigens, Polyomavirus Transforming; Atrial Natriuretic Factor; Cell Line, Transformed; Cell Polarity; Cyclic AMP; Cyclic GMP; Isoproterenol; Kidney Tubules, Collecting; Probenecid; Rabbits | 1996 |
Action of acetylcholine on regional myocardial work and metabolism in vivo: association with cyclic GMP.
Topics: Acetylcholine; Animals; Cyclic GMP; Dogs; Female; Heart; Isoproterenol; Male; Myocardium; Oxygen Consumption | 1996 |
Biphasic effects of intrapipette cyclic guanosine monophosphate on L-type calcium current and contraction of guinea pig ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channels; Cyclic GMP; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Ventricular Function | 1996 |
In rat pinealocytes the cyclic GMP response to NO is regulated by Ca2+ and protein kinase C.
Topics: Animals; Calcium; Calmodulin; Cyclic GMP; Isoproterenol; Male; Nitric Oxide; Nitroprusside; Ouabain; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Monoester Hydrolases; Pineal Gland; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley | 1995 |
Impairment of cGMP- and cAMP-mediated vasorelaxations in rats with chronic heart failure.
Topics: Animals; Aorta, Thoracic; Cardiac Output, Low; Chronic Disease; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Heart; Isoproterenol; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Norepinephrine; Pulmonary Artery; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilation | 1996 |
Inhibition of nitric oxide synthase augments myocardial contractile responses to beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Animals; Coronary Vessels; Cyclic GMP; Dobutamine; Dogs; Enzyme Inhibitors; Female; Heart; Injections; Isoproterenol; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ventricular Function | 1996 |
Phosphorylation-independent inhibition by intracellular cyclic nucleotides of brain inwardly rectifying K+ current expressed in Xenopus oocytes.
Topics: Adrenergic beta-Agonists; Animals; Barium; Brain; Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dibutyryl Cyclic GMP; Guinea Pigs; Isoproterenol; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Xenopus | 1997 |
Impaired relaxing response to isoprenaline in isolated thoracic aorta of nephrotic rats: decrease in release of EDRF from endothelial cells.
Topics: Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Nephrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Vasodilation | 1997 |
Circulating antibodies against rat parotid gland M3 muscarinic receptors in primary Sjögren's syndrome.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Animals; Antibodies, Blocking; Atropine; Carbachol; Carbamates; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin G; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Parotid Gland; Phenylcarbamates; Phosphatidylinositols; Piperidines; Pirenzepine; Protease Inhibitors; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Sjogren's Syndrome | 1996 |
Angiotensin II potentiates vasodilation of rat aorta by cAMP elevating agonists.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Sprague-Dawley; Vasodilation | 1997 |
Effects of atrial natriuretic factor on glucose metabolism in isolated adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Animals; Atrial Natriuretic Factor; Carbon Dioxide; Cell Count; Cyclic AMP; Cyclic GMP; Glucose; Guanylate Cyclase; Insulin; Isoproterenol; Lipid Metabolism; Male; Natriuretic Peptide, C-Type; Peptide Fragments; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor | 1997 |
Heterogeneity of beta-adrenoceptors in guinea-pig brain: radioligand binding and cyclic nucleotide generation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Binding, Competitive; Cerebellum; Cyclic AMP; Cyclic GMP; Female; Guinea Pigs; Inositol Phosphates; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Male; Pindolol; Population; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta; Signal Transduction; Vasodilator Agents | 1997 |
Role of nitric oxide, cyclic GMP and superoxide in inhibition by adenosine of calcium current in rabbit atrioventricular nodal cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Calcium-Transporting ATPases; Cell Separation; Coloring Agents; Cyclic GMP; Isoproterenol; Methylene Blue; Nitric Oxide; Patch-Clamp Techniques; Rabbits; Superoxides; Xanthine Oxidase | 1997 |
cAMP induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle.
Topics: Animals; Aorta; Blood Platelets; Bucladesine; Carbon Monoxide; Cells, Cultured; Coculture Techniques; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Induction; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Isoproterenol; Muscle, Smooth, Vascular; omega-N-Methylarginine; Polymerase Chain Reaction; Protoporphyrins; Rats; RNA, Messenger; Transcription, Genetic | 1997 |
Gallbladder relaxation in patients with pigment and cholesterol stones.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cholelithiasis; Cholesterol; Colforsin; Cyclic AMP; Cyclic GMP; Electric Stimulation; Enzyme Activation; Gallbladder; Humans; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Pigments, Biological; Vasoactive Intestinal Peptide | 1997 |
Involvement of cyclic nucleotide-dependent protein kinases in cyclic AMP-mediated vasorelaxation.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Aorta; Calcium; Cardiotonic Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pyrazines; Pyrrolidinones; Rats; Rats, Wistar; Rolipram; Signal Transduction; Sulfonamides; Thionucleotides | 1997 |
Basal muscarinic activity does not impede beta-adrenergic activation in rabbit hearts in controls or thyroxine-induced cardiac hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Atropine; Body Weight; Cardiomegaly; Cyclic AMP; Cyclic GMP; Isoproterenol; Muscarinic Antagonists; Myocardium; Organ Size; Rabbits; Receptors, Adrenergic, beta; Receptors, Muscarinic; Thyroxine | 1997 |
KATP channels contribute to beta- and adenosine receptor-mediated pulmonary vasorelaxation.
Topics: Acetylcholine; Adenosine; Adenylyl Cyclases; Animals; ATP-Binding Cassette Transporters; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Glyburide; In Vitro Techniques; Isoproterenol; KATP Channels; Kinetics; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Tolbutamide; Vasodilation | 1997 |
Comparative effects of continuous warm blood and intermittent cold blood cardioplegia on coronary reactivity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood; Calcimycin; Colforsin; Coronary Vessels; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Guanidines; Heart Arrest, Induced; In Vitro Techniques; Isoproterenol; Microcirculation; Pinacidil; Potassium Channels; Swine; Temperature; Vasodilation; Vasodilator Agents | 1997 |
Nitric oxide reduces myocardial contractility in isoproterenol-stimulated rat hearts by a mechanism independent of cyclic GMP or cyclic AMP.
Topics: Aminoquinolines; Animals; Cyclic AMP; Cyclic GMP; Isoproterenol; Male; Myocardial Contraction; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley | 1997 |
Cyclic GMP-dependent protein kinase activation in the absence of negative inotropic effects in the rat ventricle.
Topics: Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Carbachol; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Isoproterenol; Male; Muscarinic Agonists; Myocardial Contraction; Myocardium; Nitroprusside; Rats; Rats, Wistar; Ventricular Function, Right | 1997 |
Activation of soluble guanylyl cyclase by YC-1 in aortic smooth muscle but not in ventricular myocardium from rat.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Guanylate Cyclase; Indazoles; Isoproterenol; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1997 |
cGMP facilitates calcium current via cGMP-dependent protein kinase in isolated rabbit ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Calcium Channels; Colforsin; Cyclic GMP; Electric Conductivity; Enzyme Inhibitors; Female; Heart; Isoproterenol; Male; Membrane Potentials; Protein Kinases; Rabbits; Thionucleotides | 1998 |
The effect of chronic treatment with trandolapril on cyclic AMP-and cyclic GMP-dependent relaxations in aortic segments of rats with chronic heart failure.
Topics: Acetylcholine; Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Cardiac Output, Low; Colforsin; Cyclic AMP; Cyclic GMP; Hemodynamics; Indoles; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Wistar; Vasodilator Agents | 1998 |
Possible involvement of nitric oxide-cGMP pathway in the negative chronotropic effect of CD-832, a novel dihydropyridine derivative.
Topics: Animals; Calcium Channel Blockers; Cyclic GMP; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Molsidomine; Niacinamide; Nifedipine; Nitric Oxide | 1998 |
Ceramide selectively inhibits calcium-mediated potentiation of beta-adrenergic-stimulated cyclic nucleotide accumulation in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Calcium; Ceramides; Cyclic AMP; Cyclic GMP; Drug Synergism; Genistein; Isoproterenol; Male; Meperidine; Phenylephrine; Pineal Gland; Potassium; Potassium Chloride; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
Regulation of cardiac myocyte contractile function by inducible nitric oxide synthase (iNOS): mechanisms of contractile depression by nitric oxide.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcysteine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Culture Media, Conditioned; Cyclic AMP; Cyclic GMP; Enzyme Induction; GTP-Binding Proteins; In Vitro Techniques; Isoproterenol; Lipopolysaccharides; Macrophages, Alveolar; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley | 1998 |
Capacitative Ca2+ entry is involved in cAMP synthesis in mouse parotid acini.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium; Calcium Channels; Carbachol; Cell Compartmentation; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; In Vitro Techniques; Ionomycin; Ionophores; Isoenzymes; Isoproterenol; Lanthanum; Mice; Muscarinic Agonists; Parotid Gland; Phosphodiesterase Inhibitors; Thapsigargin | 1998 |
Role of nitric oxide in cardiac beta-adrenoceptor-inotropic response.
Topics: Animals; Atrial Function; Cardiotonic Agents; Cyclic GMP; Heart Atria; Isoproterenol; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Stimulation, Chemical | 1998 |
Atrial natriuretic peptide modulates alveolar type 2 cell adenylyl and guanylyl cyclases and inhibits surfactant secretion.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Atrial Natriuretic Factor; Bronchodilator Agents; Cell Membrane; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Epithelial Cells; GTP-Binding Proteins; Guanylate Cyclase; Isoproterenol; Ligands; Pertussis Toxin; Phosphatidylcholines; Pulmonary Alveoli; Rats; Surface-Active Agents; Virulence Factors, Bordetella | 1998 |
Atrial natriuretic factor-induced amylase output in the rat parotid gland appears to be mediated by the inositol phosphate pathway.
Topics: Adrenergic beta-Agonists; Amylases; Animals; Atrial Natriuretic Factor; Cyclic GMP; Drug Synergism; Inositol Phosphates; Isoproterenol; Male; Parotid Gland; Phosphatidylinositols; Propranolol; Rats; Rats, Wistar | 1998 |
Liposomal VIP attenuates phenylephrine- and ANG II-induced vasoconstriction in vivo.
Topics: Acetylcholine; Angiotensin II; Animals; Arterioles; Calcimycin; Cheek; Cricetinae; Cyclic GMP; Drug Carriers; Indomethacin; Isoproterenol; Liposomes; Male; Mesocricetus; Mouth Mucosa; Nitroglycerin; Phenylephrine; Protein Structure, Secondary; Vasoactive Intestinal Peptide; Vasoconstriction; Vasodilator Agents | 1998 |
Chronic L-arginine treatment increases cardiac cyclic guanosine 5'-monophosphate in rats with aortic stenosis: effects on left ventricular mass and beta-adrenergic contractile reserve.
Topics: Adrenergic beta-Agonists; Animals; Aortic Valve Stenosis; Arginine; Blood Pressure; Calcium; Case-Control Studies; Cyclic GMP; Hypertension; Hypertrophy, Left Ventricular; Isoproterenol; Longitudinal Studies; Male; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Random Allocation; Rats; Rats, Wistar; Signal Transduction; Systole; Ventricular Function, Left; Ventricular Pressure | 1998 |
Regulation of ciliary beat frequency by both PKA and PKG in bovine airway epithelial cells.
Topics: Animals; Bronchi; Bucladesine; Carbazoles; Cattle; Chromatography, Ion Exchange; Cilia; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Indoles; Isoproterenol; Kinetics; Nitroprusside; Pyrroles; Time Factors | 1998 |
The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.
Topics: Adrenergic beta-Agonists; Arginine; Cyclic GMP; Ethanolamines; Female; Heart; Heart Ventricles; Humans; Isoproterenol; Kinetics; Male; Middle Aged; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3 | 1998 |
ATP-sensitive K+ channels in smooth muscle cells of guinea-pig mesenteric lymphatics: role in nitric oxide and beta-adrenoceptor agonist-induced hyperpolarizations.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Guinea Pigs; Isoproterenol; Isoquinolines; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Receptors, Adrenergic, beta; Sulfonamides | 1998 |
Modulation of cAMP-mediated vasorelaxation by endothelial nitric oxide and basal cGMP in vascular smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Cyclic GMP; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Isoproterenol; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Thoracic Arteries; Vasodilation | 1998 |
Effect of DMPPO, a phosphodiesterase type 5 inhibitor, on hypoxic pulmonary hypertension in rats.
Topics: Allopurinol; Animals; Atrial Natriuretic Factor; Cyclic GMP; Drug Interactions; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nitroprusside; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Time Factors; Vasodilation | 1998 |
Demonstration of action-potential-producing cells in the rat pineal gland in vitro and their regulation by norepinephrine and nitric oxide.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Cyclic GMP; Electrophysiology; Isoproterenol; Male; Neurons; Nitric Oxide; Nitroarginine; Nitroprusside; Norepinephrine; Penicillamine; Pineal Gland; Rats; Rats, Sprague-Dawley; Sulfhydryl Reagents; Sympathomimetics | 1998 |
Myorelaxant activity of 2-t-butyl-4-methoxyphenol (BHA) in guinea pig gastric fundus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Antihypertensive Agents; Antioxidants; Barium; Butylated Hydroxyanisole; Calcium Channel Agonists; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Indoles; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Nifedipine; Nitroprusside; Tetraethylammonium; Vasodilator Agents | 1998 |
Differential regulation of phospholipase A2 (PLA2)-dependent Ca2+ signaling in smooth muscle by cAMP- and cGMP-dependent protein kinases. Inhibitory phosphorylation of PLA2 by cyclic nucleotide-dependent protein kinases.
Topics: Alkaloids; Animals; Arachidonic Acid; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Indoles; Intestines; Isoproterenol; Isoquinolines; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Nitroprusside; Phospholipases A; Phospholipases A2; Phosphorylation; Rabbits; Signal Transduction; Sulfonamides; Thionucleotides; Vasoactive Intestinal Peptide | 1998 |
Regulation of the L-type Ca2+ channel current in rat pinealocytes: role of basal phosphorylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic beta-Agonists; Alkaloids; Animals; Antifungal Agents; Calcium Channels; Calcium Channels, L-Type; Carbazoles; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Indoles; Isoproterenol; Isoquinolines; Male; Marine Toxins; Membrane Potentials; Nerve Tissue Proteins; Norepinephrine; Okadaic Acid; Oxazoles; Patch-Clamp Techniques; Phosphoric Monoester Hydrolases; Phosphorylation; Pineal Gland; Protein Kinase C; Pyrans; Rats; Rats, Sprague-Dawley; Spiro Compounds; Sulfonamides; Sympathomimetics | 1999 |
Endothelial defect mediates attenuated vasorelaxant response to isoproterenol after lung transplantation.
Topics: Adrenergic beta-Agonists; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Endothelium, Vascular; Isoproterenol; Lung Transplantation; Oxypurinol; Pulmonary Artery; Transplantation, Autologous; Vasodilation | 1999 |
Positive inotropy due to lowering cyclic GMP is also mediated by increases in cyclic AMP in control and hypertrophic hearts.
Topics: Animals; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Dogs; Enzyme Inhibitors; Guanylate Cyclase; Heart; Hypertrophy, Left Ventricular; In Vitro Techniques; Isoproterenol; Methylene Blue; Myocardium; Oxygen Consumption | 1998 |
Tumor necrosis factor-alpha decreases the phosphorylation levels of phospholamban and troponin I in spontaneously beating rat neonatal cardiac myocytes.
Topics: Animals; Animals, Newborn; Blotting, Western; Calcium-Binding Proteins; Contractile Proteins; Culture Techniques; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Heart; Isoproterenol; Myocardium; Myosin Light Chains; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Wistar; Troponin I; Tumor Necrosis Factor-alpha | 1999 |
E4021, a selective phosphodiesterase 5 inhibitor, potentiates the vasodilator effect of inhaled nitric oxide in isolated perfused rat lungs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Inhalation; Animals; Bronchodilator Agents; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Hypertension, Pulmonary; In Vitro Techniques; Isoproterenol; Lung; Male; Nitric Oxide; Nitroprusside; Perfusion; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperidines; Pulmonary Circulation; Quinazolines; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation | 1999 |
The nitric oxide donors, SNAP and DEA/NO, exert a negative inotropic effect in rat cardiomyocytes which is independent of cyclic GMP elevation.
Topics: Animals; Cardiotonic Agents; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Penicillamine; Quinoxalines; Rats; Rats, Wistar | 1999 |
Multiple cyclic nucleotide phosphodiesterases in human trabecular meshwork cells.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cells, Cultured; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; DNA; DNA Primers; Humans; Isoenzymes; Isoproterenol; Nitroprusside; Phosphodiesterase Inhibitors; Radioimmunoassay; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Trabecular Meshwork | 1999 |
Beta 3-adrenoceptor stimulation induces vasorelaxation mediated essentially by endothelium-derived nitric oxide in rat thoracic aorta.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Nadolol; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Tetrahydronaphthalenes; Vasoconstriction; Vasodilation | 1999 |
Effects of C-type natriuretic peptide on rat cardiac contractility.
Topics: Animals; Atrial Natriuretic Factor; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Kinetics; Male; Myocardial Contraction; Natriuretic Peptide, C-Type; Papillary Muscles; Phosphorylation; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Troponin I | 1999 |
Development of human and rabbit vaginal smooth muscle cell cultures: effects of vasoactive agents on intracellular levels of cyclic nucleotides.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Alprostadil; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Female; Humans; Isoproterenol; Muscle, Smooth; Nitroprusside; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Piperazines; Purines; Rabbits; Sildenafil Citrate; Sulfones; Vagina; Vasoactive Intestinal Peptide; Vasodilator Agents | 1999 |
Influence of increase in osmotic pressure with sucrose on relaxation and cyclonucleotides levels in isolated rat aorta.
Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Hypertonic Solutions; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Osmotic Pressure; Pinacidil; Rats; Rats, Sprague-Dawley; Sucrose; Vasodilator Agents | 1999 |
A cyclic nucleotide PDE5 inhibitor corrects defective mucin secretion in submandibular cells containing antibody directed against the cystic fibrosis transmembrane conductance regulator protein.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Antibodies; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Isoproterenol; Mucins; Purinones; Pyridazines; Pyridines; Rats; Rolipram; Submandibular Gland | 1999 |
Identification of G protein-coupled signaling pathways in cardiac fibroblasts: cross talk between G(q) and G(s).
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Angiotensin II; Animals; Bradykinin; Calcium; Carbachol; Cardiotonic Agents; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Isoproterenol; Male; Myocardium; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Signal Transduction; Sympathomimetics; Type C Phospholipases; Uridine Triphosphate; Vasoconstrictor Agents | 2000 |
Cyclic GMP attenuates cyclic AMP-stimulated inotropy and oxygen consumption in control and hypertrophic hearts.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Isoproterenol; Molsidomine; Myocardial Contraction; Oxygen Consumption; Rabbits; Vasodilator Agents | 2000 |
Ceramide inhibits L-type calcium channel currents in rat pinealocytes.
Topics: Animals; Calcium Channels, L-Type; Cells, Cultured; Cyclic AMP; Cyclic GMP; Isoproterenol; Male; Membrane Potentials; Patch-Clamp Techniques; Pineal Gland; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sphingosine | 1999 |
Down regulation of myocardial beta1-adrenoceptor signal transduction system in pacing-induced failure in dogs with aortic stenosis-induced left ventricular hypertrophy.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adrenergic beta-Agonists; Analysis of Variance; Animals; Aortic Valve Stenosis; Cardiac Pacing, Artificial; Cyclic AMP; Cyclic GMP; Disease Models, Animal; Dogs; Down-Regulation; Heart Failure; Hypertrophy, Left Ventricular; Isoproterenol; Myocardium; Oxygen Consumption; Protein Binding; Receptors, Adrenergic, beta-1; Signal Transduction | 2000 |
Endoplasmic reticulum contribution to the relaxant effect of cGMP- and cAMP-elevating agents in feline aorta.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Calcium-Binding Proteins; Cats; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endoplasmic Reticulum; Enzyme Activation; In Vitro Techniques; Isoproterenol; Nitroprusside; Phosphorylation; Vasodilation | 2000 |
Natriuretic peptides: a new lipolytic pathway in human adipocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipocytes; Adrenergic beta-Agonists; Adult; Animals; Atrial Natriuretic Factor; Cell Membrane; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Female; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Lipolysis; Middle Aged; Natriuretic Peptide, Brain; Natriuretic Peptide, C-Type | 2000 |
Nitric oxide synthesis causes inositol phosphate production and Ca2+ release in rat parotid acinar cells.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cyclic GMP; Fluorescein; Indicators and Reagents; Inositol Phosphates; Isoproterenol; Male; Nitric Oxide; Parotid Gland; Rats; Rats, Wistar; Substance P | 2000 |
Functional identification of phosphodiesterase activity in human trabecular meshwork cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Cells, Cultured; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Humans; Isoproterenol; Nitroprusside; Piperidines; Quinazolines; Signal Transduction; Trabecular Meshwork | 2000 |
Endothelin-1 as a protective factor against beta-adrenergic agonist-induced apoptosis in cardiac myocytes.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Anti-Bacterial Agents; Apoptosis; Azepines; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Flavonoids; Heart; Indoles; Isoproterenol; Myocardium; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sirolimus | 2000 |
cGMP-dependent protein kinase mediates stimulation of L-type calcium current by cGMP in rabbit atrial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Alkaloids; Animals; Blotting, Western; Calcium Channels, L-Type; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Heart Atria; Indoles; Isoproterenol; Myocardium; Nitric Oxide Donors; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rabbits; Stimulation, Chemical; Time Factors | 2000 |
Regional differences in signalling transduction pathways among smooth muscle cells from rabbit colon.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Signaling; Colon; Cyclic AMP; Cyclic GMP; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Peptide Fragments; Rabbits; Tachykinins; Vasoactive Intestinal Peptide | 2000 |
Protein kinase G reverses all isoproterenol induced changes of cardiac single L-type calcium channel gating.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Analysis of Variance; Animals; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Ion Channel Gating; Isoproterenol; Male; Mice; Myocardium; Okadaic Acid; Patch-Clamp Techniques; Phosphoric Monoester Hydrolases; Second Messenger Systems | 2000 |
Positive inotropic effects of NO donors in isolated guinea-pig and human cardiomyocytes independent of NO species and cyclic nucleotides.
Topics: Animals; Cardiotonic Agents; Cells, Cultured; Cyclic AMP; Cyclic GMP; Diethylamines; Dose-Response Relationship, Drug; Glutathione; Guinea Pigs; Humans; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Penicillamine; S-Nitrosoglutathione; Stimulation, Chemical | 2000 |
Role of heme oxygenase-carbon monoxide pathway in pathogenesis of cirrhotic cardiomyopathy in the rat.
Topics: Animals; Blotting, Western; Carbon Monoxide; Cardiomyopathies; Cardiotonic Agents; Cyclic GMP; DNA Primers; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Isoproterenol; Liver Cirrhosis; Male; Methylene Blue; Myocardial Contraction; Papillary Muscles; Protoporphyrins; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2001 |
Vascular beta-adrenergic receptor system is dysfunctional after myocardial infarction.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Aorta; Aurora Kinases; Blood Pressure; Carotid Arteries; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; GTP-Binding Proteins; Heart Failure; In Vitro Techniques; Isoproterenol; Ligation; Muscle, Smooth, Vascular; Myocardial Infarction; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Ventricular Pressure | 2001 |
cAMP- and cGMP-independent stretch-induced changes in the contraction of rat atrium.
Topics: Adrenergic beta-Agonists; Animals; Atrial Function; Biomechanical Phenomena; Calcium; Cyclic AMP; Cyclic GMP; Isoproterenol; Male; Mechanoreceptors; Myocardial Contraction; Rats; Rats, Sprague-Dawley | 2000 |
The role of nitric oxide in the mechanism of penile erection.
Topics: Acetylcholine; Adenosine Triphosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenergic Fibers; Alprostadil; Animals; Atropine; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; Isoenzymes; Isoproterenol; Macaca nemestrina; Male; Microcirculation; Models, Biological; Muscarinic Antagonists; Muscle, Smooth; Muscle, Smooth, Vascular; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Penile Erection; Penis; Propranolol; Second Messenger Systems; Vasodilator Agents | 2000 |
Sulfhydryl G proteins and phospholipase A(2)-associated G proteins are involved in adrenergic signal transduction in the rat pineal gland.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Alkaloids; Animals; Arylamine N-Acetyltransferase; Benzylisoquinolines; Cyclic AMP; Cyclic GMP; Ethylmaleimide; GTP-Binding Proteins; Intercellular Signaling Peptides and Proteins; Isoproterenol; Male; Nitric Oxide; Nitroprusside; p-Methoxy-N-methylphenethylamine; Peptides; Pertussis Toxin; Phenylephrine; Phospholipases A; Phospholipases A2; Pineal Gland; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Signal Transduction; Sulfhydryl Reagents; Virulence Factors, Bordetella; Wasp Venoms | 2001 |
Evidence that the anti-spasmogenic effect of the beta-adrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Guinea Pigs; Isoenzymes; Isoproterenol; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Pyridazines; Trachea | 2001 |
cGMP-mediated inhibition of cardiac L-type Ca(2+) current by a monoclonal antibody against the M(2) ACh receptor.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Antibodies, Monoclonal; Autoantibodies; Calcium Channels, L-Type; Colforsin; Cyclic GMP; Enzyme Inhibitors; Guanosine; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Membrane Potentials; Muscle Fibers, Skeletal; Myocardium; Oxadiazoles; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Quinoxalines; Receptor, Muscarinic M2; Receptors, Muscarinic | 2001 |
Nitric oxide inhibition of cAMP synthesis in parotid acini: regulation of type 5/6 adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoenzymes; Isoproterenol; Mice; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Parotid Gland; Phosphoric Diester Hydrolases; Quinoxalines; Thapsigargin; Triazoles | 2001 |
Endothelial NO and prostanoid involvement in newborn and juvenile pig pial arteriolar vasomotor responses.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Age Factors; Animals; Animals, Newborn; Arterioles; Bradykinin; Cardiotonic Agents; Cardiovascular Agents; Cerebrovascular Circulation; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Female; Hypercapnia; Iloprost; Indomethacin; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Pia Mater; Swine; Vasodilation; Vasodilator Agents | 2001 |
Myocyte function and [Ca 2+ ]i homeostasis during early allogenic heart transplant rejection.
Topics: Animals; Arginine; Calcium; Cyclic GMP; Graft Rejection; Heart Transplantation; Homeostasis; Isoproterenol; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Myocardial Contraction; Nitric Oxide Synthase; Transplantation, Homologous | 2001 |
Potentiation of cyclic AMP and cyclic GMP accumulation by p38 mitogen-activated protein kinase (p38MAPK) inhibitors in rat pinealocytes.
Topics: Anacardic Acids; Animals; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Interleukin-1; Ionomycin; Isoproterenol; Male; Marine Toxins; Mitogen-Activated Protein Kinases; Oxazoles; p38 Mitogen-Activated Protein Kinases; Phosphoric Diester Hydrolases; Pineal Gland; Rats; Rats, Sprague-Dawley; Salicylates; Tetradecanoylphorbol Acetate | 2001 |
Increased lipolysis in adipose tissue and lipid mobilization to natriuretic peptides during low-calorie diet in obese women.
Topics: Adipocytes; Adipose Tissue; Adult; Cyclic GMP; Diet, Reducing; Female; Humans; Infusions, Intravenous; Isoproterenol; Lipid Metabolism; Lipolysis; Middle Aged; Natriuretic Agents; Natriuretic Peptide, Brain; Obesity; Women's Health | 2002 |
PKA-dependent activation of PDE3A and PDE4 and inhibition of adenylyl cyclase V/VI in smooth muscle.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dichlororibofuranosylbenzimidazole; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; Isoproterenol; Muscle, Smooth; Phosphorylation; Rabbits; Stomach; Sympathomimetics; Thionucleotides | 2002 |
Cyclic AMP-mediated increase in L-type calcium current (ICa,L) by nitroglycerin in guinea-pig ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Signaling; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dialysis; Guinea Pigs; Heart Ventricles; Isoproterenol; Methylene Blue; Nitroglycerin | 2002 |
Control of renin secretion from rat juxtaglomerular cells by cAMP-specific phosphodiesterases.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Isoproterenol; Isoquinolines; Juxtaglomerular Apparatus; Membrane Potentials; Mice; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Renin; Tetrahydroisoquinolines; Thionucleotides | 2002 |
Natriuretic peptide-dependent lipolysis in fat cells is a primate specificity.
Topics: Adipocytes; Adult; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dogs; Female; Guanylate Cyclase; Humans; Isoproterenol; Lipolysis; Macaca fascicularis; Male; Middle Aged; Natriuretic Agents; Primates; Rabbits; Rats; Rats, Wistar; Receptors, Cell Surface; RNA, Messenger; Rodentia; Species Specificity | 2002 |
Attenuation of cAMP accumulation in adult rat cardiac fibroblasts by IL-1beta and NO: role of cGMP-stimulated PDE2.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 2; Enzyme Induction; Fibroblasts; Guanylate Cyclase; Interleukin-1; Isoproterenol; Male; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley | 2002 |
Methacholine-induced cGMP production is regulated by nitric oxide generation in rabbit submandibular gland cells.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcium; Chelating Agents; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Isoenzymes; Isoproterenol; Methacholine Chloride; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Phenylephrine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Submandibular Gland; Substance P | 2002 |
Role of cyclic nucleotides in regulation of pulmonary artery tone in rabbits.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic GMP; Dipyridamole; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pulmonary Artery; Rabbits; Signal Transduction; Sympathomimetics; Theophylline; Vasodilator Agents | 2003 |
Expression of constitutively active guanylate cyclase in cardiomyocytes inhibits the hypertrophic effects of isoproterenol and aortic constriction on mouse hearts.
Topics: Adenylyl Cyclases; Animals; Aorta; Blood Pressure; Blotting, Northern; COS Cells; Cyclic GMP; DNA, Complementary; Echocardiography; Guanylate Cyclase; Hypertrophy; Isoproterenol; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocardium; Peptides; Protein Structure, Tertiary; Rats; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Tissue Distribution; Transfection; Transgenes | 2003 |
Single L-type Ca(2+) channel regulation by cGMP-dependent protein kinase type I in adult cardiomyocytes from PKG I transgenic mice.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels, L-Type; Carbachol; Cardiotonic Agents; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Hydrazines; Isoproterenol; Mice; Mice, Transgenic; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides | 2003 |
Pertussis toxin-sensitive G protein but not NO/cGMP pathway mediates the negative inotropic effect of carbachol in adult rat cardiomyocytes.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electric Stimulation; GTP-Binding Proteins; Injections, Intraperitoneal; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase; omega-N-Methylarginine; Oxadiazoles; Pertussis Toxin; Quinoxalines; Rats; Time Factors | 2004 |
[Vasonatrin peptide attenuates the enhancement of electrically-induced intracellular calcium transient by isoproterenol in rat cardiac myocytes].
Topics: Animals; Atrial Natriuretic Factor; Calcium; Calcium Channels; Cyclic GMP; Depression, Chemical; Female; Guanylate Cyclase; Isoproterenol; Male; Myocytes, Cardiac; Rats; Receptors, Atrial Natriuretic Factor | 2004 |
Daidzein and 17 beta-estradiol enhance nitric oxide synthase activity associated with an increase in calmodulin and a decrease in caveolin-1.
Topics: Acetylcholine; Animals; Aorta; Body Weight; Calmodulin; Caveolin 1; Caveolins; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Estradiol; Fulvestrant; Gene Expression; Injections, Subcutaneous; Isoflavones; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Nitroprusside; Organ Size; Phenoxybenzamine; Rats; Rats, Sprague-Dawley; Testis | 2004 |
cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenoviridae; Adrenergic beta-Agonists; Animals; Carbolines; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 5; Fluorescence Resonance Energy Transfer; Genetic Vectors; Guanylate Cyclase; Isoproterenol; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Second Messenger Systems; Sildenafil Citrate; Soluble Guanylyl Cyclase; Sulfones; Tadalafil | 2005 |
Acute impairment of contractile responses by 17beta-estradiol is cAMP and protein kinase G dependent in vascular smooth muscle cells of the porcine coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenylyl Cyclase Inhibitors; Animals; Carbazoles; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Drug Interactions; Estradiol; Indoles; Isometric Contraction; Isoproterenol; Muscle, Smooth, Vascular; Swine; Thionucleotides; Time Factors | 2005 |
Fos-related antigen 2 (Fra-2) memorizes photoperiod in the rat pineal gland.
Topics: Acetyltransferases; Adaptation, Physiological; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Blotting, Western; Cyclic AMP; Cyclic GMP; DNA-Binding Proteins; Drug Interactions; Female; Fos-Related Antigen-2; Gene Expression Regulation; Heat-Shock Proteins; Isoproterenol; Male; Organ Culture Techniques; Peptide Fragments; Phenylephrine; Photoperiod; Pineal Gland; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription Factors | 2005 |
Modulation of voltage-dependent Ba2+ currents in the guinea-pig gastric antrum by cyclic nucleotide-dependent pathways.
Topics: Animals; Barium; Bucladesine; Calcium Channels, L-Type; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocytes, Smooth Muscle; Peptides; Pyloric Antrum; Thionucleotides | 2005 |
Selective cannabinoid receptor agonist HU-210 decreases pump function of isolated perfused heart: role of cAMP and cGMP.
Topics: Adrenergic beta-Agonists; Animals; Cannabinoid Receptor Agonists; Cyclic AMP; Cyclic GMP; Dronabinol; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Radioimmunoassay; Rats | 2004 |
Absence of force suppression in rabbit bladder correlates with low expression of heat shock protein 20.
Topics: Adenylyl Cyclases; Animals; Carbachol; Carotid Arteries; Colforsin; Cyclic GMP; Enzyme Activation; HSP20 Heat-Shock Proteins; Immunologic Techniques; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Myosin Light Chains; Phosphorylation; Rabbits; Staining and Labeling; Swine; Urinary Bladder | 2005 |
Functional interaction of a beta-adrenergic agonist and cyclic GMP phosphodiesterase inhibitor in control and hypertrophic cardiomyocytes.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenergic beta-Agonists; Animals; Cardiomegaly; Cell Enlargement; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Hypertension, Renal; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocytes, Cardiac; Purinones; Rabbits | 2006 |
Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway.
Topics: Adenine; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Enzyme Activation; Isoproterenol; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide; Norepinephrine; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction | 2006 |
Heart failure reduces both the effects and interaction between cyclic GMP and cyclic AMP.
Topics: Animals; Cardiac Output, Low; Cardiotonic Agents; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Disease Models, Animal; Dogs; Hypertrophy, Left Ventricular; Isoproterenol; Myocardial Contraction; Myocardium; Oxygen Consumption | 2006 |
Beta3-adrenoceptor in the eel (Anguilla anguilla) heart: negative inotropy and NO-cGMP-dependent mechanism.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anguilla; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Depression, Chemical; Ethanolamines; GTP-Binding Proteins; Heart; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Nadolol; Nitric Oxide; Propanolamines; Receptors, Adrenergic, beta-3; Signal Transduction | 2006 |
Inhibition of nitric oxide synthase enhances contractile response of ventricular myocytes from streptozotocin-diabetic rats.
Topics: Animals; Calcium Signaling; Cyclic GMP; Diabetes Mellitus, Experimental; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Streptozocin; Time Factors | 2007 |
Regulation of human internal mammary and radial artery contraction by extracellular and intracellular calcium channels and cyclic adenosine 3', 5' monophosphate.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclases; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; Extracellular Fluid; Humans; In Vitro Techniques; Intracellular Fluid; Isoproterenol; Mammary Arteries; Milrinone; Phenylephrine; Potassium Chloride; Radial Artery; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
Muscarinic modulation of the sodium-calcium exchanger in heart failure.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Cardiac Pacing, Artificial; Cell Separation; Cells, Cultured; Cyclic GMP; Disease Models, Animal; Drug Antagonism; Female; Heart Failure; Isoproterenol; Male; Muscarinic Agonists; Myocytes, Cardiac; Niflumic Acid; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Adrenergic, beta; Receptors, Muscarinic; Sodium-Calcium Exchanger; Swine; Tachycardia | 2007 |
Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Atrial Natriuretic Factor; Cell Compartmentation; Cell Membrane; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 5; Cytosol; Enzyme Activation; Guanylate Cyclase; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Protein Kinase Inhibitors; Purines; Receptors, Adrenergic, beta; Second Messenger Systems; Sildenafil Citrate; Sulfones | 2007 |
Nitroglycerin on contractile force in canine cardiac Purkinje fibers.
Topics: Animals; Cardiotonic Agents; Cobalt; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Methylene Blue; Muscle Strength; Myocardial Contraction; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Potassium; Potassium Channel Blockers; Purkinje Fibers; Tetraethylammonium | 2007 |
Endothelium removal augments endothelium-independent vasodilatation in rat mesenteric vascular bed.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Nitroprusside; Perfusion; Peripheral Nervous System; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; Splanchnic Circulation; Vasodilation; Vasodilator Agents | 2008 |
Serofendic acid promotes stellation induced by cAMP and cGMP analogs in cultured cortical astrocytes.
Topics: Adrenergic beta-Agonists; Amides; Animals; Astrocytes; Bucladesine; Carbazoles; Cell Shape; Cells, Cultured; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Neuroprotective Agents; Pyridines; Pyrroles; Rats; Rats, Wistar; rho-Associated Kinases; Tetradecanoylphorbol Acetate; Time Factors | 2009 |
Phosphodiesterase 5 restricts NOS3/Soluble guanylate cyclase signaling to L-type Ca2+ current in cardiac myocytes.
Topics: Animals; Calcium Channels, L-Type; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 5; Enzyme Activation; Guanylate Cyclase; Indazoles; Ion Channel Gating; Isoproterenol; Mice; Models, Biological; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase Type III; Phosphodiesterase 5 Inhibitors; Purinones; Receptors, Adrenergic, beta; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase | 2009 |
Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury.
Topics: Adrenergic beta-Agonists; Animals; Benzoates; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Dogs; Female; Gene Expression; Guanylate Cyclase; Heart Function Tests; Isoproterenol; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Survival Rate; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta1 | 2009 |
Role of Ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Calcium; Calcium Signaling; Calmodulin; Cardiomegaly; Cardiotonic Agents; Cells, Cultured; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heart Ventricles; Humans; Isoproterenol; Male; Mice; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Second Messenger Systems | 2009 |
Controlling myocyte cGMP: phosphodiesterase 1 joins the fray.
Topics: Angiotensin II; Animals; Calcium; Calcium Signaling; Calmodulin; Cardiomegaly; Cardiotonic Agents; Cells, Cultured; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heart Ventricles; Humans; Isoproterenol; Male; Mice; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Second Messenger Systems | 2009 |
KMUP-1 attenuates isoprenaline-induced cardiac hypertrophy in rats through NO/cGMP/PKG and ERK1/2/calcineurin A pathways.
Topics: Animals; Calcineurin; Cardiomegaly; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Drug Delivery Systems; Fibrosis; Isoproterenol; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase; Piperidines; Rats; Rats, Wistar; Signal Transduction; Survival Rate; Xanthines | 2010 |
Angiotensin-(1-7) stimulates high atrial pacing-induced ANP secretion via Mas/PI3-kinase/Akt axis and Na+/H+ exchanger.
Topics: Angiotensin I; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiac Pacing, Artificial; Cardiotonic Agents; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Myocytes, Cardiac; Peptide Fragments; Phosphatidylinositol 3-Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sodium-Hydrogen Exchangers | 2010 |
Hyperpolarization-activated ion channels as targets for nitric oxide signalling in deep cerebellar nuclei.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Cerebellar Nuclei; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Electrophysiology; Guanylate Cyclase; Ion Channels; Isoproterenol; Neurons; Nitric Oxide; Rats; Rats, Sprague-Dawley; Signal Transduction | 2010 |
Physiological evidence for β3-adrenoceptor in frog (Rana esculenta) heart.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Blotting, Western; Cyclic AMP; Cyclic GMP; Female; Heart; Isoproterenol; Male; Myocardium; Nadolol; Nitric Oxide; Phentolamine; Propanolamines; Rana esculenta; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2010 |
Identification of cytosolic phosphodiesterases in the erythrocyte: a possible role for PDE5.
Topics: Animals; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Cytosol; Erythrocytes; Humans; Isoenzymes; Isoproterenol; Male; Phosphodiesterase Inhibitors; Purinones; Rabbits; Spermine; Vinca Alkaloids | 2011 |
Different β-adrenoceptor subtypes coupling to cAMP or NO/cGMP pathways: implications in the relaxant response of rat conductance and resistance vessels.
Topics: Animals; Aorta; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Isoproterenol; Male; Mesenteric Arteries; Myocytes, Smooth Muscle; Nitric Oxide; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; RNA, Messenger; Signal Transduction; Vasodilation | 2013 |
Effects of taurine on myocardial cGMP/cAMP ratio, antioxidant ability, and ultrastructure in cardiac hypertrophy rats induced by isoproterenol.
Topics: Animals; Antioxidants; Cardiomegaly; Creatine Kinase, MB Form; Cyclic AMP; Cyclic GMP; Glutathione; Humans; Isoproterenol; Male; Malondialdehyde; Myocardium; Myocytes, Cardiac; Rats; Rats, Wistar; Taurine | 2013 |
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium-Binding Proteins; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Heart Failure; Isoproterenol; Male; Mice; Mice, Knockout; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, C-Type; Phosphorylation; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Thionucleotides; Troponin I | 2013 |
Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.
Topics: Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Heart Ventricles; Humans; Hypertrophy; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Transgenic; Myocytes, Cardiac; Neurotransmitter Agents; Nitric Oxide Synthase; Receptors, Adrenergic, beta-3; Signal Transduction; Ventricular Remodeling | 2014 |
Pyocyanin inhibits both nitric oxide-dependent and -independent relaxation in porcine coronary arteries.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Diethylamines; Dinoprost; Female; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Pseudomonas aeruginosa; Pyocyanine; Swine; Vasodilation | 2015 |
Enhanced endothelium-dependent relaxation of rat pulmonary artery following β-adrenergic overstimulation: involvement of the NO/cGMP/VASP pathway.
Topics: Adrenergic beta-Agonists; Animals; Cell Adhesion Molecules; Cyclic GMP; Endothelium, Vascular; Isoproterenol; Male; Microfilament Proteins; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphoproteins; Pulmonary Artery; Rats; Rats, Wistar; Signal Transduction; Vasodilation | 2015 |
Microdomain switch of cGMP-regulated phosphodiesterases leads to ANP-induced augmentation of β-adrenoceptor-stimulated contractility in early cardiac hypertrophy.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Biosensing Techniques; Cardiomegaly; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 3; Disease Models, Animal; Enzyme Activation; Female; Fluorescence Resonance Energy Transfer; Guanine Nucleotide Exchange Factors; Isoproterenol; Membrane Microdomains; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Protein Transport; Receptor Cross-Talk; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Second Messenger Systems; Time Factors | 2015 |
Increased Rho-kinase-mediated prostate contractions associated with impairment of β-adrenergic-cAMP-signaling pathway by chronic nitric oxide deficiency.
Topics: Adenosine Triphosphate; Amides; Animals; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phenylephrine; Prostate; Pyridines; Rats; rho-Associated Kinases; Signal Transduction | 2015 |
Cardiac actions of atrial natriuretic peptide: new visions of an old friend.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cyclic GMP; Female; Isoproterenol; Membrane Microdomains; Myocardial Contraction; Myocytes, Cardiac; Receptors, Adrenergic, beta | 2015 |
The soluble guanylate cyclase stimulator riociguat and the soluble guanylate cyclase activator cinaciguat exert no direct effects on contractility and relaxation of cardiac myocytes from normal rats.
Topics: Animals; Benzoates; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Female; Guanylate Cyclase; Isoproterenol; Muscle Relaxation; Myocardial Contraction; Myocytes, Cardiac; Oxadiazoles; Pyrazoles; Pyrimidines; Quinoxalines; Rats; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Thionucleotides; Verapamil | 2015 |
Transgenic overexpression of transient receptor potential vanilloid subtype 1 attenuates isoproterenol-induced myocardial fibrosis in mice.
Topics: Animals; Cyclic GMP; Fibroblasts; Fibrosis; Hemodynamics; Isoproterenol; Male; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Size; Proto-Oncogene Proteins c-akt; Signal Transduction; TRPV Cation Channels; Ventricular Function | 2016 |
Suppression of Npr1, not Npr2 gene function induces hypertrophic growth in H9c2 cells in vitro.
Topics: Adrenergic beta-Agonists; Animals; Cell Line; Cell Proliferation; Cell Size; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Gene Expression Regulation; Isoproterenol; Myocytes, Cardiac; Rats; Receptors, Adrenergic, beta-1; Receptors, Atrial Natriuretic Factor; RNA, Small Interfering; Signal Transduction | 2017 |
Vasonatrin peptide, a synthetic natriuretic peptide, attenuates myocardial injury and oxidative stress in isoprenaline-induced cardiomyocyte hypertrophy.
Topics: Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cardiotonic Agents; Cyclic GMP; Humans; Isoproterenol; Mice; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Oxidative Stress; Primary Cell Culture; Rats; Signal Transduction; Superoxide Dismutase | 2021 |
Cellular Mechanisms of the Anti-Arrhythmic Effect of Cardiac PDE2 Overexpression.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Gene Expression Regulation; Guanine Nucleotide Exchange Factors; Heart; Humans; Isoproterenol; Mice; Myocytes, Cardiac | 2021 |
The bitter taste receptor (TAS2R) agonist denatonium promotes a strong relaxation of rat corpus cavernosum.
Topics: Animals; Chloroquine; Cyclic GMP; Isoproterenol; Male; Rats; Taste | 2023 |
Theophylline-induced endothelium-dependent vasodilation is mediated by increased nitric oxide release and phosphodiesterase inhibition in rat aorta.
Topics: Animals; Aorta; Aorta, Thoracic; Calcium; Cyclic GMP; Endothelium, Vascular; Isoproterenol; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Phosphoric Diester Hydrolases; Rats; Theophylline; Vasodilation | 2023 |